LOCUS       gnlProkkaGEEOCELN_4    15641 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GEEOCELN_4.
ACCESSION   gnlProkkaGEEOCELN_4
VERSION     gnlProkkaGEEOCELN_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 00:56:05
            Original ID  :: gnl|Prokka|GEEOCELN_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 196070
            Orig. end    :: 211711
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15641
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:10641]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..10641
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..15641
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15641
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             1656..2477
                     /locus_tag="ctg4_207"
                     /transl_table=11
                     /translation="MEYPYREKFLSWAKDVKHYRESTVMLYDYTVNSFYNYFYSQSEHG
                     NDIRLVRPQDITNYLVNIQEQHHIVANTANKYYFHLKKYFTFLYSNQLIDEYPLIDLKT
                     YKVNKYTNITLGWQQYLPEIFKIAELSDDAKLELFLISQNIEPKGLLNITFGQLRNFNT
                     ENIGILLDNIEVKPDNYFVFSLKNDPEKPLNSLNSLLMRVRPDEEILNMTLAPSKLRQS
                     YIYNYLLTNKDKSEIELLDHLHLSIKSLVYYRQNLLNIDFNNFVYETPKEK"
     CDS             2513..2812
                     /locus_tag="ctg4_208"
                     /transl_table=11
                     /translation="MKKYLLFILSIVVALLTWIPNTRLFLTDSNIGTILILVLTIFVCV
                     FSVIYNKHSRSLWYIFSFILGLSPILFLIFVGIFLVIRNAFCTMINFQVETGKI"
     CDS             complement(2887..3729)
                     /locus_tag="ctg4_209"
                     /transl_table=11
                     /translation="MEEKFLNYDIPNFVKESPNYLKLFEKERIILKNKHDKWGIYFSEE
                     LGYSLEYKENLGKVDYVYDSFLEAYSQADNDGEVWFSDEIAHEVFGEPEDEDLNEKGEF
                     GNLSDDFFWTKNHLIFRHHGDYSVKNLEDEYQEWKNLDKKVKEDSFTHENFLLIYEWLR
                     THPNFWKENVHGNRVFWETSHMNLNFMDIYPTSSETSGKVEWWAEGGYHVLDDTDVPYA
                     TTYYHDIALDCGGNTYEQAVLNFAKNVWLQTHGMLKDKEARRDAIFERWVKDSGCESD"
     CDS             complement(3833..4984)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 56.4; E-value:
                     3.8e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_210"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSARFRNFSTMIIIPFTILLLVVVIFSFFGKKEI
                     TIQGAGTLEALGNNPVIQSTVNSPIEKNYLKEGKYVKKGDTLLIYNNVSIQDKGKLYNS
                     QKEILDRQLAALNLLKQGVQDNHDSFGEDDEFGYRNDLKSYLQQRNTYLTENTMIQDKS
                     KNDKAKQSSINNELKKQSGSATSIADFDSSKYDIEINNQKISDLQSSKLSSIDQEIIKI
                     KQNISELNANINENNNTNREYKVKAVRDGILHINDEYSESHYISAGANLAQILPVLKNQ
                     KTLKVKAYVSTADISSIKVGQKVRFKVTRNVSKPIILTGKIYKISISPVEIGKENYYQI
                     EAKTDIENTNKDLLKYGMQGRMVVITGKTTFFEYYKNKXXNNN"
     CDS             complement(5001..7160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 314.6; E-value:
                     2.1e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_211"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.7e-44, bitscore:
                     142.8, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1077.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRKYRKDYVSQVDESDCGVASLAMILKHYGSALSLAYLRNIAKT
                     TMEGTTALGLVKTAQALGMETQAVKADMSLFGMKDITYPFIVHVVKEETLLHYYVVLKA
                     TPRYILIADPAPDVGITKMSYERFEKEWTGITLFIVPGIEYKPTKETRQSLISLFSKLF
                     KQKQLIVNIVLAALLITIISILGSYFLQGIIDTYIPNGMHSTLAIIALGLLVIYVFNSI
                     FTYARDFLLAILGQRLSIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVVSIFLDVSIVVIMGIILAIQNLKLLGITLITLPIYTIIILTFTKAFERLNNKQMES
                     NAILSSSIIEDIQGIETIKALNSEQMRYRKIDSQFVDYLRKSLAYIKTDSLQQALKLFI
                     QQTLNVIVLWLGANLVISNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDRKAVHDVTQLQGDIIFKDVDYHYGYGENVLDKVNLTLKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFAPVSGSIKLNNHDINNIDKHALRSYINYIPQNPYIFTGTIE
                     DNLRLGNRSNVTDEDILMACKIAMIDIDIAKMPLQLKTELDENANILSGGQKQRITIAR
                     ALLSPAQVLIFDESTSGLDAITEKKLIDNLMKLKSKTIIFIAHRLSIAKRTNNILVLDS
                     GKIVEKGRHDELLAKKGYYYNLVNS"
     CDS             complement(7310..7549)
                     /locus_tag="ctg4_212"
                     /transl_table=11
                     /translation="MVETSIIILLIVGFMVISRLKVNFTRNSKYAGFLLLILLNLNGLM
                     RTPMLTMRGLILLGTLMIFIVMLIKEIRQNRKYN"
     CDS             complement(7585..8379)
                     /locus_tag="ctg4_213"
                     /transl_table=11
                     /translation="MEEYGIIICDDEKDQVRRIHDLVKYAIWSLEDSADSKGKKFKITL
                     EANSYIEVADYLEDNKVDSGVYFLDIELSKDKADRDGIDLAEFIRQKDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDNDEVIQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDILYIITTPKSHRLKIVTVNGMGEFTGDIKKLEVENDFLEKISQSCLANPS
                     NIVEINLSTRSISFKDGYKETFPRRSKAKMKSLIERYNLKTV"
     CDS             complement(8393..8740)
                     /locus_tag="ctg4_214"
                     /transl_table=11
                     /translation="MIENLSNKYNSFDIVRILGIVYDNAIEESLEFGDEAKIDTMIYQE
                     NGELEIEIRNRYRDTDLTIQDIKKSGFTTKKNHDGLGLANIEELSQSYNDIFINYQIKD
                     GWFTFLMVMSI"
     CDS             complement(8905..9591)
                     /locus_tag="ctg4_215"
                     /transl_table=11
                     /translation="MTPTRKSKKYNLLFILLTFPVILLINGVGDIIGFFAPFIEIFIFY
                     IVYRQLTLDYRLCGRLLMLDLFSYITFGASALFFTLFTNYYTMVSVIILDVSLNIFEYI
                     ILTKTTIIEKLDDEYGLLYFYLILYIWISSMVIYYLTTYVFNIDAVSYIIATVVVVSQL
                     FFSLFVYSINKKIRQDKLSLQQINDLKIYTQQLESSQRGLRKFKHDYQNMLLSLKLSVK
                     KVMIKS"
     CDS             complement(9678..9794)
                     /locus_tag="ctg4_216"
                     /transl_table=11
                     /translation="MKFEVLTEKKLQKIAGGATKKGGFKRWQCIFTFFGVCK"
     CDS             complement(9914..10081)
                     /locus_tag="ctg4_217"
                     /transl_table=11
                     /translation="MIFGITVIVAYSIFISIYTSLKEEGHHKLFDEKVIEKNKKISYVR
                     AWVLNFMWWL"
     CDS             complement(10226..10432)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_218"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.9e-11,
                     bitscore: 36.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLDKRFTIMTEDNLASVNGGKNGYGGSGNRWVHCGAGIVGGAL
                     IGAIGGPWSAVAGGISGGFTSCR"
     CDS             complement(10450..10641)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_219"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 6.7e-16,
                     bitscore: 52.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEFTVLTECELAKVDGGKRGPNCVGNFLGGLFAGAAAGVPLGPA
                     GIVGGANLGMVGGALTCL"
     CDS             complement(10650..10907)
                     /locus_tag="ctg4_220"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEEMS
                     YLDYIQTPKMIIVTIFCLVGGSTLLYLLDTAMKVNKHMKG"
     CDS             complement(11595..11768)
                     /locus_tag="ctg4_221"
                     /transl_table=11
                     /translation="MNNNFVQVDKKELAHIIGGRNSYDYIDSGQFGYDIGCTIANTKFF
                     KRLRHSNQNICS"
     CDS             12001..12264
                     /locus_tag="ctg4_222"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLFLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFESTDDKHPLNRIDFGLQLLFIFISIIKFFLISGR"
     CDS             12553..13521
                     /locus_tag="ctg4_223"
                     /transl_table=11
                     /translation="MRYIKFTLLIYSFLLTWGITTNSISADEVTPTTTSETTVTPQSQS
                     TPVDSNDEDAAIEEKFYSHDVTIDKYNQNVANFNKVNTDTVKTMVTENSNNLDQVLYIG
                     RPTCYFCRQASPHLRDFNQLINNQLYYYDIDAEPNAHDFAFKEIGISGTPTTMRLKNGK
                     VVSAWIGGEKTGQEFYDFLFSADANKLADSYIIKKTVSTDTSNPVITNNQNVEPTVKPI
                     STNINQLKEEKTTPELVNTTSQSSKPVKKIHNQTTNKKNKNSVLPQLGVVPLYHXPXFK
                     LPIPRXXPKXXERXIXXXSFLVLYIGITIWTGLSLKNWDKK"
     CDS             complement(13688..14047)
                     /locus_tag="ctg4_224"
                     /transl_table=11
                     /translation="MKAIYRGRKVDVWQVSRDNVQPDWVKDAFEHNGLRWLHGSGNKVR
                     IYWPAVTRAKKGIVRTILNDISASFVGIAGGSVSMYDIGFEGDVIDFTNSKVVTAEKFA
                     KXYRXVSEXXXXXIX"
     CDS             complement(14068..14334)
                     /locus_tag="ctg4_225"
                     /transl_table=11
                     /translation="MDYLVIKAIIWIFFITSAILEVNYKKKYGELDKRARKQATLGTFL
                     IVTTIFDEGYENKILYIIVLIALLVYVVLVIYRLVMAIKDRKK"
ORIGIN
        1 gaatcatttt ttcagaaaaa tcaaacaatt ttttgccaga atattcttta ctaccaatct
       61 tcaagctaca gaaatttcct tcttcatctg caggaataca tccatggaat aagagattgc
      121 cattatatgt acggtacata ctacctttat tcatcataaa atctagatga cgttttaatt
      181 ttgtagaatg ttgaatggaa attaataatt catctacaat cgcattttct tcatctgtta
      241 attcactagg atttttaggg tctacagtgt tgaaacaagt attttgtaac ggatattctt
      301 taccatttaa actaattaca tttttcttgt aatctatctt attaagtaaa tctcgatcat
      361 ccatttccaa ttctggtctt ctagctataa ctttcccttc aagcttaaat tgcatcatcg
      421 caacagcttg atgaatttgc gtgatttgta gcttttcgcc gttgaatcta tacccatcac
      481 cattagtcaa tttaggtcta aattgaggat tatcctcata ttgctcctca gcaaatctcg
      541 aaaggtgacg taagttaatc ccataagcat cttctatgat gttcaagtta ttatatcttg
      601 cacaaattct caataaattc aacatacata gttttgagcc tgccattgca cctagccata
      661 gtaaatcatg atttccccat tgcatatcga cagaatgata attcatcaat ctatccataa
      721 ttttgtctgg ttcttctccc ctatcgtaaa catcgcccag aacatgtaag tgatctacta
      781 ctaatctttg aattgtgtaa caggtagcaa taataaattt acctgcttga tctaatttca
      841 aaatattctt caaaagttga ttaatataac ttctcttatt aaattcttgt ggatcgttat
      901 ataataattc ttctgttatg tatacaaaat taggatttag tgctttacga acctttgagc
      961 gcgtatactt gcttcctgat aattctaaaa attctaataa gtgggaaatg ttatctaagt
     1021 accattgttg tagctcattt tctgtacgta attttttctt tactagagcc aattcatctt
     1081 caggatagta gattagcaaa gcaaaatctt gcatcgtttg ttctgtcatt ctatctgaaa
     1141 agtaatcttg aattttctgt ttaatactcc cagaaccatt tcttaaaacg tgatcaaatg
     1201 ctgtatactc cccatgcaaa tcacttacaa agtgttcagt tccctttgga agatgcaaaa
     1261 ttgcttccaa gttcataatt tcggtaatca catcttgttt cgtaggatat ttttctttta
     1321 ataagttatg cgaataagca ttcatgtcaa cttgcttatt tactaattct tcattatcat
     1381 caaaattcat cgccatcaac ccctatatta tggtcatcaa tatggttttt acattacgcc
     1441 ttgaaaaggt ttttgtcaat acattttaat tatttaatta caaacactta tttataaata
     1501 ttaaaactta tttatatgta aattaaccat aactaacact taatnaaatn cnnnatnnna
     1561 aattntnttc antaacgctt tttagagngt atctttgtat gtgatataat ttcagtagtt
     1621 atagttgcaa cgtaattttt agtgaggtgt tatatatgga gtacccttat cgtgaaaaat
     1681 ttctatcttg ggctaaagat gttaaacatt atcgtgaaag taccgtaatg ttgtacgatt
     1741 ataccgtcaa tagtttctat aactattttt atagtcaatc agaacatggt aatgatattc
     1801 gtcttgtccg acctcaagat atcactaact atcttgtaaa tattcaagaa caacatcata
     1861 ttgttgctaa tactgctaat aaatactatt ttcacttgaa aaagtatttt acttttctct
     1921 atagtaatca gttgattgat gaatatcctt taatcgattt aaaaacttac aaagtcaata
     1981 aatacactaa tattacactt ggttggcagc aatatctacc tgaaattttc aaaattgcgg
     2041 aactttctga tgatgcaaaa ttagaacttt ttctaatctc tcaaaatatc gaaccaaagg
     2101 gattacttaa tattactttt ggacagcttc gaaactttaa tacagaaaat attggaattt
     2161 tgctagataa tattgaagta aaacctgata attatttcgt attctcacta aaaaacgatc
     2221 ctgaaaaacc attgaattcg ttaaattcat tattaatgag agttagacct gatgaagaaa
     2281 ttttgaatat gacactagcc ccttcaaaat taagacaaag ttatatttac aattatctcc
     2341 ttactaataa agataaatcc gaaattgaac ttctagatca tcttcatcta tctattaagt
     2401 cattagtata ttatcgtcaa aacttgctca atattgactt taataatttt gtttatgaaa
     2461 ctccaaaaga aaagtagttt ttgccctttc tcatcataag gagataatta aaatgaaaaa
     2521 atatttatta tttattttat ctattgttgt tgcactacta acttggattc cgaacactcg
     2581 tctattttta acggattcca atataggaac tattcttata ttagttttga ctatttttgt
     2641 atgtgttttt tctgtaattt ataataaaca ctctcgttct ctttggtata tattttcttt
     2701 tatattagga ttaagtccta tactattttt aattttcgtt ggtatttttt tagtcattag
     2761 aaatgccttt tgcaccatga ttaactttca agtagaaacc ggaaaaattt aaaaaatcgc
     2821 caaagatttg cactaatcct tggcgatttt tacttggcgt aagctattaa attttatctt
     2881 aagtattcag tcagattcgc atccagaatc cttaacccat ctttcaaaga tagcgtcacg
     2941 tcttgcttct ttatccttca acattccatg tgtttgtaac caaacgtttt tcgcaaaatt
     3001 cagtactgct tgctcatatg tattaccacc acaatccaaa gcaatatcat gatagtaagt
     3061 tgttgcgtat gggacatcag tatcatctaa aacatgatat ccaccctcag cccaccattc
     3121 tacttttcca cttgtttcac tagaagttgg ataaatatcc ataaagttta aattcatgtg
     3181 tgatgtctcc cagaagactc tattcccatg aacattttct ttccagaaat taggatgtgt
     3241 cctaagccat tcataaatta atagaaaatt ttcatgcgta aaactgtctt ctttgacttt
     3301 cttatccaaa tttttccatt cttggtactc atcttctagg ttcttaacac tatagtcacc
     3361 atggtgtctg aaaattaggt gattctttgt ccaaaagaaa tcatcgctca aatttccaaa
     3421 ttctcctttt tcattaagat cttcatcttc aggttcacca aatacttcat gtgctatttc
     3481 atctgaaaac caaacttctc cgtcattatc agcttgagag taggcttcca agaaagaatc
     3541 atatacataa tctacttttc ctaaattttc cttatattcc aatgaatatc ctaattcctc
     3601 actaaagtag atcccccatt tatcatgttt attctttagg atgatacgtt ctttttcaaa
     3661 tagttttagg taattaggtg attcttttac aaaattaggt atatcataat tcaaaaattt
     3721 ttcttccatg tcattcatcc tcacttgtta atctacaata atcctaccct aatctttacg
     3781 aaataaaaat ctaccagtgg tttaatggta aagaatattc aaaaaatttt tattaattat
     3841 tattnnntan cttattctta taatattcaa aaaatgttgt ttttcctgta attacaacca
     3901 ttcgtccttg cataccatac ttcaataaat ccttattagt attttcaata tctgttttag
     3961 cttcaatttg ataataattt tcttttccta tctctactgg agaaatcgat atcttatata
     4021 tttttccagt caaaataata ggtttagata cgtttctagt tactttgaat cttacttttt
     4081 gccctacttt tatggaggaa atatctgctg tacttacata tgcctttact tttaaagttt
     4141 tttgattttt caaaactggt agtatctgag ctaaattagc ccctgcactt atataatgac
     4201 tttcactata ctcatcgtta atatgtaaaa ttccgtctct aacagccttt accttatact
     4261 ctctattagt attattattt tcattaatat tagcgttcaa ttctgaaata ttttgcttga
     4321 tttttataat ttcttgatca atagaactta acttacttga ctgtaaatca cttatttttt
     4381 gattgtttat ctcaatatcg tatttagacg aatcaaaatc agctatactt gtagcagacc
     4441 cactttgttt cttcaactca ttattaatcg aactttgttt ggctttgtcg tttttagatt
     4501 tatcctggat cattgtattt tctgttaaat acgtattcct ttgctgtagg taactcttta
     4561 aatcattacg ataaccaaat tcatcatctt ctccaaaaga atcatgattg tcttgaacac
     4621 cttgtttaag taagttcaaa gctgccaact gtctatctaa gatttctttt tgtgaattat
     4681 acagtttccc cttatcttgt atactcacat tattataaat aagtaatgta tctccttttt
     4741 ttacatactt tccttctttt aaataatttt tttcaatagg actatttaca gttgattgaa
     4801 taacaggatt atttcccaat gcctcaagtg ttcctgcacc ttggatagtt atctcctttt
     4861 ttccaaaaaa gctaaaaatt actaccacca acaataaaat tgtaaaagga ataataatca
     4921 tagttgaaaa gtttctaaat ctagctgaat aaaattcgct gctttctaaa aatttatctt
     4981 ccataataca atactccccc ctaactatta actaaattgt agtagtatcc ttttttagct
     5041 aataattcat catgtctacc cttttctaca atttttccgc tatctaatac tagaatatta
     5101 tttgttcgct tagctataga taatctatgt gcaataaaaa ttatagtttt tgactttaat
     5161 ttcattaaat tatcaattag ttttttctcc gtaatagcat ctaacccact tgtagattca
     5221 tcaaaaatca atacttgtgc tggagataat aaggctctag caattgtaat tctttgtttt
     5281 tgtccacctg ataaaatatt agcattttca tctaattcag tttttaattg tagtggcatc
     5341 ttcgctatat ctatatcaat cattgctatt ttacaagcca taagaatatc ctcatcagtc
     5401 acattagatc gattacctag tctaagatta tcttctattg tcccggtaaa aatatatgga
     5461 ttctgtggta tataattaat ataggaacgc agtgcatgct tatcaatatt attaatatca
     5521 tgattattta gttttatact ccctgaaact ggagcaaaaa aattcaccaa tagtttaact
     5581 aacgttgatt tgccagagcc actcatacct actatagtta gtttttctcc ctgttttaaa
     5641 gtcaaattaa ccttatccaa aacattttca ccataaccat agtgataatc aacatcttta
     5701 aatataatgt ctccttgaag ttgagtaaca tcatgaacag cctttctatc tttaaattca
     5761 ctttcaacca agtaaacctc attcaaacga ttgtgagcta cccttgcact ctgcaatttt
     5821 ggctgtaaat ttatgatatt ttgtaatgga ttcacaaaat aacttaatag tgcgttaaaa
     5881 gtcattaatt gtcctataga gagttgatta ctaattacca gatttgcccc taaccatagg
     5941 actataacat ttaatgtttg ttgaataaat aactttaatg cttgttgcaa cgagtctgtt
     6001 tttatatatg ctaacgattt acgcaaatag tccacaaatt gactatcaat tttgcggtaa
     6061 cgcatttgtt cgctgtttaa ggcttttatt gtttctattc cttgaatatc ttcaataata
     6121 gatgaactaa gtatcgcatt actttccatt tgtttattat tcaatctttc aaatgccttt
     6181 gtaaatgtaa gaataataat cgtgtaaatt ggaagtgtga taagagttat tcctagtaat
     6241 ttaagatttt gaatagccaa gattattccc ataataacta caatacttac atctaaaaaa
     6301 atagatacca cagtacttgc taaagcatct ataattttac tagcatcatt gaaacgagaa
     6361 actatttccc cagtttttct ggtcgcaaaa aattccatag gcaactcaaa aatatgtcta
     6421 atataactta aaataatttc aatcgaaagt cgttgtccta aaattgctaa taaaaaatcc
     6481 cttgcatatg taaaaattga attgaacaca tatattacta gtaatcccaa agcaataatt
     6541 gccagtgtac tatgcatacc attaggaata tatgtatcaa ttattccctg taaaaaatat
     6601 gatcccaata tactaataat tgtaattaac aaagctgcca atacaatatt aactattagt
     6661 tgcttttgct taaataattt actaaatagt gatattaatg attgtctagt ctcttttgtc
     6721 ggcttgtatt caattcctgg aacgatgaat aaagtaatcc ctgtccattc tttttcaaaa
     6781 cgttcatacg acattttagt tatccctaca tctggagctg gatcagcaat taaaatatat
     6841 ctaggcgttg ctttcaatac tacataataa tgtaataacg tctcttcttt aaccacatgt
     6901 acaataaatg gatatgtaat gtctttcatt ccaaaaagag acatatcagc ttttacggct
     6961 tgtgtttcca ttcctaaagc ctgtgctgtc ttaacaagac ctaaagctgt agtcccctcc
     7021 attgttgtct tagcaatgtt ccttaaatac gctaatgata gtgctgatcc atagtgtttc
     7081 aaaatcatag ccaacgaagc cacgccacaa tcagattcgt ctacttgtga aacgtaatct
     7141 tttcgatact ttcttaacaa gaaaaatccc ccttattttc tattattatt tttataccaa
     7201 aaatatcatt tctctcttat cttatgtatt agttatcaaa tttggcgatt tttaatacat
     7261 atttggttaa taaagagggt tggaataccc taagttccaa ccctctttat taattatatt
     7321 ttctattttg tctaatttct ttaatcaaca taactataaa aatcattaat gttcccaata
     7381 agattaaacc tctcattgtt aacataggag ttcgcataag cccatttaaa ttcagtaata
     7441 ttaacaatag aaaccctgca tacttactat ttctcgtaaa attcactttc aaccttgaaa
     7501 ttaccataaa ccctacaatt agcaatataa taatacttgt ttctaccatg atcattcacc
     7561 acctacacta ataaacacaa aaaattaaac tgttttcaaa ttataccttt caatcaaact
     7621 tttcatttta gccttacttc tcctaggaaa agtctcctta tatccatctt taaaagaaat
     7681 actccttgtt gacaggttaa tttcaacaat attactagga ttagctaaac aagattgtga
     7741 tattttttct agaaaatcat tttctacctc taacttctta atatcgcctg taaactcacc
     7801 cataccatta actgtaacta ttttcaatct atgtgactta ggagtggtaa taatatatag
     7861 aatatcattg atattttcgt taataattct tctgcccatt ttatagctaa atgtcatttt
     7921 ctttatggca tgagattccc taattctcct tgcagctaat gataaagtct catttagtcg
     7981 tttttgaatc acttcatcat tatcattttt agtaataaaa tccaatgctc cagtacgacg
     8041 tcgataagtc attgctgcta gattttcata agctgtaata aaaattatct gtgcatttgg
     8101 atctttttgt ctaataaatt cagctaaatc tatcccatct ctatctgctt tatctttact
     8161 aagttcaata tctaaaaaat aaactccact atctactttg ttatcttcca aataatcggc
     8221 tacttcaata taactattag cttccaaagt tattttaaat tttttacctt tactgtcagc
     8281 agaatcttct aaagaccaaa tagcatattt aactagatca tgtatccttc taacttgatc
     8341 cttctcatcg tcacaaataa taattccata ttcttccaaa ttaaactacc ccttaaatgc
     8401 tcataaccat aaggaaagta aaccaaccat ctttaatttg ataattaata aaaatatcat
     8461 tataagattg acttaattct tctatattag ctaatcctaa tccgtcatga ttcttcttag
     8521 ttgtaaaacc tgattttttt atatcttgaa ttgttagatc ggtatctcga taacgatttc
     8581 taatctcaat ttcaagttca ccattttctt gataaatcat agtatctatc ttagcttcat
     8641 caccaaactc aagactttct tcaattgcat tatcgtacac aattcctaat attctaacaa
     8701 tgtcaaacga gttatactta ttcgacaagt tttctatcac aattcgacat tcaaaagaat
     8761 attgaatatt gttttgaaag attctattca acttactgat aaatagactc tttaataatt
     8821 catctttaac attgtcaaca tcattaaact gccataatac tttatcttct aaagtcttac
     8881 ttgaatattc agctagttta tctattaact ctttatcatg acttttttta cactgagttt
     8941 caagcttaat agcatatttt gataatcgtg cttaaattta cgtaaacctc gctggctact
     9001 ttctaactgt tgtgtataaa tttttagatc attaatttgt tgtaaactta atttatcctg
     9061 ccgtattttc ttattaatgg aatatacaaa taatgaaaag aacaattggc taacaacaac
     9121 taccgtagct ataatatacg atactgcatc tatattaaat acatatgttg ttagatagta
     9181 aataaccatt gaactaatcc atatgtataa aattaaataa aaatacaata atccatactc
     9241 atcatctagt ttctctatta tagtcgtctt tgttaaaatt atatattcaa aaatgtttaa
     9301 tgacacatct aatattatca cactgaccat tgtgtaataa tttgtaaata atgtaaaaaa
     9361 taatgctgaa gcaccgaatg ttatatagga aaataaatct agcattaaca accttccaca
     9421 taatctgtaa tccaaagtta gttgtctgta tacaatataa aaaataaaaa tttcaataaa
     9481 tggtgcaaaa aaaccaataa tatctccaac accattaatt aaaagaatta caggaaaagt
     9541 aagaagtata aataataaat tatacttctt acttttccta gtaggggtca aaagataaaa
     9601 aaactatatc tacaaaaagt atttataaaa taatagtgta gctactatat aaccagatgt
     9661 tgaatttaaa ttaaccatta tttacaaaca ccaaaaaatg tgaatataca ttgccatctt
     9721 ttaaagccac cctttttggt tgctccccca gctattttct gtaacttctt ttctgttaac
     9781 acttcaaact tcataaaaaa tctctccttt gttatcttta ttacaaatat agtttaacat
     9841 tttttaatct actttattcg ttttttatca tattcggttc attttaatgc ttatttggat
     9901 gaaattctta aaactatagc caccacataa aatttaacac ccacgctctc acataactta
     9961 ttttcttatt cttttctatg actttctcat caaataactt atgatgcccc tcttctttta
    10021 gactagtata aatactgata aaaatactat atgcaactat tacagtaatc ccaaatatca
    10081 tatactcact tcctaatccc aaaatatatt atgttctatt aaaaataaaa gtagtgtcaa
    10141 atttagctat atactataac ttacacttga cactacttga agaaaaatag atttatttct
    10201 tattttctaa ttcattagac ttattctaac ggcaacttgt aaagccacca gaaattccac
    10261 ccgctacggc tgaccagggt ccaccgatag ctccaattaa agctccacct acgatgccag
    10321 ctccacagtg aacccagcga tttccactac caccataacc atttttacca ccatttactg
    10381 atgctaagtt atcttcagtc ataattgtga atcttttatc tagatttttc attttaaatt
    10441 actcctatat tataaacaag taagtgctcc gcctaccatt cctaagtttg ctccacctac
    10501 aataccagct ggtccaagtg gaactcctgc agctgctcca gcaaatagac cacctaaaaa
    10561 gttacctaca cagttaggac cacgtttccc accatcaacc tttgctaact cacattctgt
    10621 caatactgta aattccttca tcatgataat catcctttca tatgtttatt tactttcatc
    10681 gcagtatcta ataagtaaag tagtgtacta ccacctacta gacaaaaaat agtaactatt
    10741 atcattttag gcgtttgaat ataatctaaa taagacattt cctcattacc aaacagccat
    10801 attcctagtg gaatcaatag tgcccaaata actggagcaa taacatatct cttctttcct
    10861 ctaatgaatc caccatccaa ccaagtctcc catagttttt ttagcatgta agaacacacc
    10921 ctttctaaaa cacttgtgaa acatatactt acacttttat tgtattatca ttccgtattc
    10981 aaatatcgat ttagcgtaaa atacnttatt ntatnccnag ttggttatct aatataaatt
    11041 ctattgtaac tataaatatt catcatctac gtggcttact tgtaactata agtactatcc
    11101 ctacagacat tagaaaaatc gaatatatta tgccactccc tagaagcaca ttgattaacc
    11161 ctataagtat ctaacctata cctatgcaat acataaatat tctatctgtc ttcttcatct
    11221 catatattta tttactttca tcgcggtatc taacaagtaa agtagtgtac tgccacctac
    11281 tagacaaaaa acagcaaata ttatccattt aggcatttaa atatagtcta aataagacat
    11341 tccttcattg tcggatagcc acatcgatag gggaagaaat attgcaaaaa taattggaat
    11401 gattacatat ctcttccttc ctctaattaa tccgccatct aaccagatat tccataattt
    11461 tttcagcann taagaacaca ncctntctaa aacacttgtg aaacatatnc ttacactttt
    11521 attgtattat cattccgtat tcaaatatcn atttagcnta aatatgttnt atacctagtt
    11581 ggttacattt ctttttaact acaaatattt tgatttgagt gtcttaatct tttaaaaaat
    11641 ttagtattag caattgtaca gcctatatcg taaccaaact gtccgctatc tatataatca
    11701 taagaatttc ttccaccaat tatatgtgcc aattctttct tatcaacttg tacaaaatta
    11761 ttattcataa cttcaacacc tcataatttt aaaaatttat tatagctata atttacactt
    11821 ataattattc acttcatctg ctctttttga ctatttcttc taattttgct aaattttatt
    11881 cttattctct tttttcaacc agataggcac cgcttactac caaattggaa aaatcccctc
    11941 aattcatcac tttctatgtg ataataaaaa tacttttata atgaattgag gtaaaaattt
    12001 atgaatagtt tttctaataa tattaatttc agcaaaattt ctgtttcact aattacttta
    12061 ttcctgttga tctggacatt agttgatgga aatctaattc atcttggtat attggctttt
    12121 tcttctttgg ttacaaccat gctacatttt cactattttg aatctactga tgacaaacat
    12181 ccattaaata gaattgattt tggattacaa ttactattta tctttatttc tattattaag
    12241 tttttcttga tttcaggaag ataacaataa gcctatcagg tatcaaatta cacctgatag
    12301 gcttatttat taacatatnt atcaacaatt ttgtacttct ttttaaattt tctttctggt
    12361 ataattttgc gattagnnnn atnnnantat tttcataata catccaatgc taaatttctt
    12421 aactagcact atttcttact tatttggtaa atagtccaaa taagtagtta ttgctaccat
    12481 tccagcagtt tatcacacta tgtagacatt atttgcaata attacatata tacgattagg
    12541 gggattgaaa aaatgagata cattaaattt actttactaa tatattcttt tttactaact
    12601 tggggaatca ccacgaatag tatatcagcg gatgaagtta cacctactac aacatctgaa
    12661 acaacagtta cgcctcaaag tcaaagtaca cctgttgatt ctaatgatga ggatgctgca
    12721 attgaagaaa aattttactc tcatgatgtt acaatcgata aatataatca aaatgtggca
    12781 aacttcaata aagttaatac tgatactgtt aaaaccatgg ttactgaaaa tagcaacaat
    12841 ctagaccaag ttctttacat tggacgtcct acttgttatt tttgtcggca agcttctcca
    12901 catctacgtg attttaacca actaataaat aatcagcttt actactatga tattgatgct
    12961 gaacctaatg ctcatgattt tgcatttaaa gaaattggaa tttctggaac cccaacaact
    13021 atgcgtttaa agaatggtaa agttgtcagt gcttggattg gtggcgaaaa aacaggacaa
    13081 gaattttatg actttttatt ttctgcagat gctaacaagt tagcagattc ctatatcata
    13141 aagaaaactg taagcacgga tacttcaaat cctgttatta caaataatca aaatgttgaa
    13201 ccaactgtta agcctatatc aacaaatata aatcagctta aagaggaaaa aactactcct
    13261 gaattggtta atactacttc acaatcatct aaacctgtta aaaaaattca taatcaaact
    13321 actaataaga aaaacaaaaa ttctgttcta ccacaattag gggttgtccc tctttatcat
    13381 canccantat ttaaacttcc tattccncga nttatnccta agcnantaga acgtantata
    13441 nngttnntct cttttctagt tctatatatt ggtatcacta tatggacagg gttgagttta
    13501 aaaaattggg ataaaaaata aaatatctaa tatagcaata ggaccaattt tttaatttat
    13561 gcaaaattat cgttttgatt tagaaaaatc aattatttgc ataaattttc taattggtcc
    13621 tatctttata tttaactttt ttcaaaattt gcaactttat ttctcacatt aatttttggg
    13681 gctaacttca nntaatacnn ntanntnant cttcaganac tanccgatan ttcttggcga
    13741 acttttcggc tgtaacgacc ttagaattgg taaaatcgat aacatctccc tcaaagccaa
    13801 tgtcatacat cgacacgctg ccaccagcta taccaacaaa agaagctgaa atatcattca
    13861 aaatagttcg tactattccc ttttttgccc tagtaactgc tggccaataa attctgactt
    13921 tattaccact gccatgtagc catcgcaacc cattatgctc aaaagcatct ttaacccaat
    13981 caggttggac attatctcta ctcacttgcc aaacatctac ttttctacct ctatagattg
    14041 ctttcatttg ctttatcacc tttcttatta ctttttccta tccttaatag ccataactaa
    14101 tctatatatc actaatacta catataccaa cagtgctatt aatactatta tatatagtat
    14161 tttattctca taaccttcat caaatattgt agttactatt agaaatgttc ctaatgttgc
    14221 ttgctttcta gctcgtttat ctaattcacc atattttttc ttataattaa cttccaaaat
    14281 tgctgatgtt ataaaaaata tccaaataat tgccttaata actaaataat ccatcattcc
    14341 accacctatt ctctattttt gccattatta tactatttta attaaattta attctatatt
    14401 ttcttaatta atactatttt ctgcttattt ggttaacaat ttatctattt caaaaaaata
    14461 gcgacaaaaa catcgctgtc ttgccactat tcccaactat ttaaataaat taagttttgc
    14521 gattctatca actgcctctt ctaaacgttc tggttcaatt aacaaaccaa ttcgtacata
    14581 accttctcca tattcgccaa aaccattccc aggagctact gctactccag cttcatttaa
    14641 aagcagatct gcaaattctt cactactata tccctttggt acttccatcc aagcgtagaa
    14701 cgttccctta ggtacaaaag ctttccatcc gattttttca gcagcttgga tgaacgcatt
    14761 tcttctagtt tcgtaacgat ctacaatctt actgatttca gcatcgcgtt ctggggcttt
    14821 caaagcatca attcctgcat attgtagagc tggaaagata cttacaaata aatgatcttg
    14881 gataagattt aaagcatcaa tgatatcagc atttcctacc gcaaaagcaa ctcgccagcc
    14941 tgccatgtta aaagtcttag agaaggtata aaattcgata ccaacatcct tagctcctgg
    15001 aatctccata aaacttaatg gtcgctctcc atcaaaacca attgcaccat atgcaaaatc
    15061 gctgatgata cctacttcat atttctttgc ccaagcaact aattcttcgt aaaattctcg
    15121 agttgcggtc gcacccgttg gattattagg gtagttaata tagaagaatt tagcctttct
    15181 agcaagttct tctggaatag atttcaaatc tggtaagaaa ttattctctt tcaaaagcgg
    15241 aactttctca aaagtgacct gcccaagtgt agctccagac caataatctg gataaccagg
    15301 atcaggtaat aaaaatacat caccaggatt catcaaagct agtggtagtt cgactaggcc
    15361 agttttagag ccaccaagaa ctgcaacttc tttttctggg tcgaatgtag tttgatactt
    15421 ttcttgatag aagtctgcta cagcttgttt aaattctggc tgtccacgaa acaatgagta
    15481 cttgtgactt tgcggactag ctacccattt ttgtgtgctc ttgacgatat attcaggagt
    15541 ttgtttatca ggattacctt gtcctagatt gataacatct actccttctg caattttttt
    15601 gttaactttg attaccaaat tagcaaagaa ttgctttggt a
//
