GCA_000173975.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaEPMDDCDP_98 (original name was: gnl|Prokka|EPMDDCDP_98)

Region	Type	From	To	Most similar known cluster		Similarity
Region 85.1	ranthipeptide	1	15,576

gnlProkkaEPMDDCDP_147 (original name was: gnl|Prokka|EPMDDCDP_147)

Region	Type	From	To	Most similar known cluster		Similarity
Region 132.1	NRPS,cyclic-lactone-autoinducer	33,643	84,797

No secondary metabolite regions were found in these records:: gnlProkkaEPMDDCDP_1 (original name was: gnl|Prokka|EPMDDCDP_1); gnlProkkaEPMDDCDP_2 (original name was: gnl|Prokka|EPMDDCDP_2); gnlProkkaEPMDDCDP_4 (original name was: gnl|Prokka|EPMDDCDP_4); gnlProkkaEPMDDCDP_5 (original name was: gnl|Prokka|EPMDDCDP_5); gnlProkkaEPMDDCDP_6 (original name was: gnl|Prokka|EPMDDCDP_6); gnlProkkaEPMDDCDP_7 (original name was: gnl|Prokka|EPMDDCDP_7); gnlProkkaEPMDDCDP_8 (original name was: gnl|Prokka|EPMDDCDP_8); gnlProkkaEPMDDCDP_9 (original name was: gnl|Prokka|EPMDDCDP_9); gnlProkkaEPMDDCDP_10 (original name was: gnl|Prokka|EPMDDCDP_10); gnlProkkaEPMDDCDP_11 (original name was: gnl|Prokka|EPMDDCDP_11); gnlProkkaEPMDDCDP_12 (original name was: gnl|Prokka|EPMDDCDP_12); gnlProkkaEPMDDCDP_13 (original name was: gnl|Prokka|EPMDDCDP_13); gnlProkkaEPMDDCDP_14 (original name was: gnl|Prokka|EPMDDCDP_14); gnlProkkaEPMDDCDP_16 (original name was: gnl|Prokka|EPMDDCDP_16); gnlProkkaEPMDDCDP_17 (original name was: gnl|Prokka|EPMDDCDP_17); gnlProkkaEPMDDCDP_18 (original name was: gnl|Prokka|EPMDDCDP_18); gnlProkkaEPMDDCDP_20 (original name was: gnl|Prokka|EPMDDCDP_20); gnlProkkaEPMDDCDP_21 (original name was: gnl|Prokka|EPMDDCDP_21); gnlProkkaEPMDDCDP_22 (original name was: gnl|Prokka|EPMDDCDP_22); gnlProkkaEPMDDCDP_23 (original name was: gnl|Prokka|EPMDDCDP_23); gnlProkkaEPMDDCDP_24 (original name was: gnl|Prokka|EPMDDCDP_24); gnlProkkaEPMDDCDP_25 (original name was: gnl|Prokka|EPMDDCDP_25); gnlProkkaEPMDDCDP_26 (original name was: gnl|Prokka|EPMDDCDP_26); gnlProkkaEPMDDCDP_27 (original name was: gnl|Prokka|EPMDDCDP_27); gnlProkkaEPMDDCDP_28 (original name was: gnl|Prokka|EPMDDCDP_28); gnlProkkaEPMDDCDP_29 (original name was: gnl|Prokka|EPMDDCDP_29); gnlProkkaEPMDDCDP_30 (original name was: gnl|Prokka|EPMDDCDP_30); gnlProkkaEPMDDCDP_31 (original name was: gnl|Prokka|EPMDDCDP_31); gnlProkkaEPMDDCDP_32 (original name was: gnl|Prokka|EPMDDCDP_32); gnlProkkaEPMDDCDP_33 (original name was: gnl|Prokka|EPMDDCDP_33); gnlProkkaEPMDDCDP_34 (original name was: gnl|Prokka|EPMDDCDP_34); gnlProkkaEPMDDCDP_35 (original name was: gnl|Prokka|EPMDDCDP_35); gnlProkkaEPMDDCDP_36 (original name was: gnl|Prokka|EPMDDCDP_36); gnlProkkaEPMDDCDP_37 (original name was: gnl|Prokka|EPMDDCDP_37); gnlProkkaEPMDDCDP_38 (original name was: gnl|Prokka|EPMDDCDP_38); gnlProkkaEPMDDCDP_39 (original name was: gnl|Prokka|EPMDDCDP_39); gnlProkkaEPMDDCDP_40 (original name was: gnl|Prokka|EPMDDCDP_40); gnlProkkaEPMDDCDP_41 (original name was: gnl|Prokka|EPMDDCDP_41); gnlProkkaEPMDDCDP_42 (original name was: gnl|Prokka|EPMDDCDP_42); gnlProkkaEPMDDCDP_44 (original name was: gnl|Prokka|EPMDDCDP_44); gnlProkkaEPMDDCDP_45 (original name was: gnl|Prokka|EPMDDCDP_45); gnlProkkaEPMDDCDP_46 (original name was: gnl|Prokka|EPMDDCDP_46); gnlProkkaEPMDDCDP_47 (original name was: gnl|Prokka|EPMDDCDP_47); gnlProkkaEPMDDCDP_48 (original name was: gnl|Prokka|EPMDDCDP_48); gnlProkkaEPMDDCDP_52 (original name was: gnl|Prokka|EPMDDCDP_52); gnlProkkaEPMDDCDP_53 (original name was: gnl|Prokka|EPMDDCDP_53); gnlProkkaEPMDDCDP_54 (original name was: gnl|Prokka|EPMDDCDP_54); gnlProkkaEPMDDCDP_55 (original name was: gnl|Prokka|EPMDDCDP_55); gnlProkkaEPMDDCDP_56 (original name was: gnl|Prokka|EPMDDCDP_56); gnlProkkaEPMDDCDP_57 (original name was: gnl|Prokka|EPMDDCDP_57); gnlProkkaEPMDDCDP_58 (original name was: gnl|Prokka|EPMDDCDP_58); gnlProkkaEPMDDCDP_59 (original name was: gnl|Prokka|EPMDDCDP_59); gnlProkkaEPMDDCDP_60 (original name was: gnl|Prokka|EPMDDCDP_60); gnlProkkaEPMDDCDP_62 (original name was: gnl|Prokka|EPMDDCDP_62); gnlProkkaEPMDDCDP_63 (original name was: gnl|Prokka|EPMDDCDP_63); gnlProkkaEPMDDCDP_64 (original name was: gnl|Prokka|EPMDDCDP_64); gnlProkkaEPMDDCDP_65 (original name was: gnl|Prokka|EPMDDCDP_65); gnlProkkaEPMDDCDP_67 (original name was: gnl|Prokka|EPMDDCDP_67); gnlProkkaEPMDDCDP_68 (original name was: gnl|Prokka|EPMDDCDP_68); gnlProkkaEPMDDCDP_70 (original name was: gnl|Prokka|EPMDDCDP_70); gnlProkkaEPMDDCDP_71 (original name was: gnl|Prokka|EPMDDCDP_71); gnlProkkaEPMDDCDP_72 (original name was: gnl|Prokka|EPMDDCDP_72); gnlProkkaEPMDDCDP_73 (original name was: gnl|Prokka|EPMDDCDP_73); gnlProkkaEPMDDCDP_74 (original name was: gnl|Prokka|EPMDDCDP_74); gnlProkkaEPMDDCDP_75 (original name was: gnl|Prokka|EPMDDCDP_75); gnlProkkaEPMDDCDP_76 (original name was: gnl|Prokka|EPMDDCDP_76); gnlProkkaEPMDDCDP_79 (original name was: gnl|Prokka|EPMDDCDP_79); gnlProkkaEPMDDCDP_81 (original name was: gnl|Prokka|EPMDDCDP_81); gnlProkkaEPMDDCDP_82 (original name was: gnl|Prokka|EPMDDCDP_82); gnlProkkaEPMDDCDP_83 (original name was: gnl|Prokka|EPMDDCDP_83); gnlProkkaEPMDDCDP_84 (original name was: gnl|Prokka|EPMDDCDP_84); gnlProkkaEPMDDCDP_85 (original name was: gnl|Prokka|EPMDDCDP_85); gnlProkkaEPMDDCDP_86 (original name was: gnl|Prokka|EPMDDCDP_86); gnlProkkaEPMDDCDP_87 (original name was: gnl|Prokka|EPMDDCDP_87); gnlProkkaEPMDDCDP_88 (original name was: gnl|Prokka|EPMDDCDP_88); gnlProkkaEPMDDCDP_89 (original name was: gnl|Prokka|EPMDDCDP_89); gnlProkkaEPMDDCDP_90 (original name was: gnl|Prokka|EPMDDCDP_90); gnlProkkaEPMDDCDP_91 (original name was: gnl|Prokka|EPMDDCDP_91); gnlProkkaEPMDDCDP_92 (original name was: gnl|Prokka|EPMDDCDP_92); gnlProkkaEPMDDCDP_93 (original name was: gnl|Prokka|EPMDDCDP_93); gnlProkkaEPMDDCDP_94 (original name was: gnl|Prokka|EPMDDCDP_94); gnlProkkaEPMDDCDP_95 (original name was: gnl|Prokka|EPMDDCDP_95); gnlProkkaEPMDDCDP_96 (original name was: gnl|Prokka|EPMDDCDP_96); gnlProkkaEPMDDCDP_97 (original name was: gnl|Prokka|EPMDDCDP_97); gnlProkkaEPMDDCDP_99 (original name was: gnl|Prokka|EPMDDCDP_99); gnlProkkaEPMDDCDP_100 (original name was: gnl|Prokka|EPMDDCDP_100); gnlProkkaEPMDDCDP_101 (original name was: gnl|Prokka|EPMDDCDP_101); gnlProkkaEPMDDCDP_102 (original name was: gnl|Prokka|EPMDDCDP_102); gnlProkkaEPMDDCDP_104 (original name was: gnl|Prokka|EPMDDCDP_104); gnlProkkaEPMDDCDP_105 (original name was: gnl|Prokka|EPMDDCDP_105); gnlProkkaEPMDDCDP_106 (original name was: gnl|Prokka|EPMDDCDP_106); gnlProkkaEPMDDCDP_107 (original name was: gnl|Prokka|EPMDDCDP_107); gnlProkkaEPMDDCDP_108 (original name was: gnl|Prokka|EPMDDCDP_108); gnlProkkaEPMDDCDP_109 (original name was: gnl|Prokka|EPMDDCDP_109); gnlProkkaEPMDDCDP_110 (original name was: gnl|Prokka|EPMDDCDP_110); gnlProkkaEPMDDCDP_111 (original name was: gnl|Prokka|EPMDDCDP_111); gnlProkkaEPMDDCDP_112 (original name was: gnl|Prokka|EPMDDCDP_112); gnlProkkaEPMDDCDP_113 (original name was: gnl|Prokka|EPMDDCDP_113); gnlProkkaEPMDDCDP_114 (original name was: gnl|Prokka|EPMDDCDP_114); gnlProkkaEPMDDCDP_115 (original name was: gnl|Prokka|EPMDDCDP_115); gnlProkkaEPMDDCDP_116 (original name was: gnl|Prokka|EPMDDCDP_116); gnlProkkaEPMDDCDP_117 (original name was: gnl|Prokka|EPMDDCDP_117); gnlProkkaEPMDDCDP_118 (original name was: gnl|Prokka|EPMDDCDP_118); gnlProkkaEPMDDCDP_119 (original name was: gnl|Prokka|EPMDDCDP_119); gnlProkkaEPMDDCDP_120 (original name was: gnl|Prokka|EPMDDCDP_120); gnlProkkaEPMDDCDP_121 (original name was: gnl|Prokka|EPMDDCDP_121); gnlProkkaEPMDDCDP_122 (original name was: gnl|Prokka|EPMDDCDP_122); gnlProkkaEPMDDCDP_123 (original name was: gnl|Prokka|EPMDDCDP_123); gnlProkkaEPMDDCDP_124 (original name was: gnl|Prokka|EPMDDCDP_124); gnlProkkaEPMDDCDP_125 (original name was: gnl|Prokka|EPMDDCDP_125); gnlProkkaEPMDDCDP_126 (original name was: gnl|Prokka|EPMDDCDP_126); gnlProkkaEPMDDCDP_127 (original name was: gnl|Prokka|EPMDDCDP_127); gnlProkkaEPMDDCDP_128 (original name was: gnl|Prokka|EPMDDCDP_128); gnlProkkaEPMDDCDP_129 (original name was: gnl|Prokka|EPMDDCDP_129); gnlProkkaEPMDDCDP_130 (original name was: gnl|Prokka|EPMDDCDP_130); gnlProkkaEPMDDCDP_132 (original name was: gnl|Prokka|EPMDDCDP_132); gnlProkkaEPMDDCDP_133 (original name was: gnl|Prokka|EPMDDCDP_133); gnlProkkaEPMDDCDP_134 (original name was: gnl|Prokka|EPMDDCDP_134); gnlProkkaEPMDDCDP_135 (original name was: gnl|Prokka|EPMDDCDP_135); gnlProkkaEPMDDCDP_136 (original name was: gnl|Prokka|EPMDDCDP_136); gnlProkkaEPMDDCDP_137 (original name was: gnl|Prokka|EPMDDCDP_137); gnlProkkaEPMDDCDP_138 (original name was: gnl|Prokka|EPMDDCDP_138); gnlProkkaEPMDDCDP_139 (original name was: gnl|Prokka|EPMDDCDP_139); gnlProkkaEPMDDCDP_140 (original name was: gnl|Prokka|EPMDDCDP_140); gnlProkkaEPMDDCDP_141 (original name was: gnl|Prokka|EPMDDCDP_141); gnlProkkaEPMDDCDP_142 (original name was: gnl|Prokka|EPMDDCDP_142); gnlProkkaEPMDDCDP_143 (original name was: gnl|Prokka|EPMDDCDP_143); gnlProkkaEPMDDCDP_144 (original name was: gnl|Prokka|EPMDDCDP_144); gnlProkkaEPMDDCDP_145 (original name was: gnl|Prokka|EPMDDCDP_145); gnlProkkaEPMDDCDP_146 (original name was: gnl|Prokka|EPMDDCDP_146); gnlProkkaEPMDDCDP_148 (original name was: gnl|Prokka|EPMDDCDP_148); gnlProkkaEPMDDCDP_149 (original name was: gnl|Prokka|EPMDDCDP_149); gnlProkkaEPMDDCDP_150 (original name was: gnl|Prokka|EPMDDCDP_150); gnlProkkaEPMDDCDP_151 (original name was: gnl|Prokka|EPMDDCDP_151); gnlProkkaEPMDDCDP_152 (original name was: gnl|Prokka|EPMDDCDP_152); gnlProkkaEPMDDCDP_153 (original name was: gnl|Prokka|EPMDDCDP_153); gnlProkkaEPMDDCDP_154 (original name was: gnl|Prokka|EPMDDCDP_154); gnlProkkaEPMDDCDP_155 (original name was: gnl|Prokka|EPMDDCDP_155); gnlProkkaEPMDDCDP_156 (original name was: gnl|Prokka|EPMDDCDP_156); gnlProkkaEPMDDCDP_157 (original name was: gnl|Prokka|EPMDDCDP_157); gnlProkkaEPMDDCDP_158 (original name was: gnl|Prokka|EPMDDCDP_158); gnlProkkaEPMDDCDP_159 (original name was: gnl|Prokka|EPMDDCDP_159); gnlProkkaEPMDDCDP_160 (original name was: gnl|Prokka|EPMDDCDP_160); gnlProkkaEPMDDCDP_161 (original name was: gnl|Prokka|EPMDDCDP_161); gnlProkkaEPMDDCDP_163 (original name was: gnl|Prokka|EPMDDCDP_163); gnlProkkaEPMDDCDP_164 (original name was: gnl|Prokka|EPMDDCDP_164); gnlProkkaEPMDDCDP_165 (original name was: gnl|Prokka|EPMDDCDP_165); gnlProkkaEPMDDCDP_166 (original name was: gnl|Prokka|EPMDDCDP_166); gnlProkkaEPMDDCDP_167 (original name was: gnl|Prokka|EPMDDCDP_167); gnlProkkaEPMDDCDP_168 (original name was: gnl|Prokka|EPMDDCDP_168); gnlProkkaEPMDDCDP_169 (original name was: gnl|Prokka|EPMDDCDP_169); gnlProkkaEPMDDCDP_170 (original name was: gnl|Prokka|EPMDDCDP_170); gnlProkkaEPMDDCDP_171 (original name was: gnl|Prokka|EPMDDCDP_171); gnlProkkaEPMDDCDP_172 (original name was: gnl|Prokka|EPMDDCDP_172); gnlProkkaEPMDDCDP_173 (original name was: gnl|Prokka|EPMDDCDP_173); gnlProkkaEPMDDCDP_174 (original name was: gnl|Prokka|EPMDDCDP_174); gnlProkkaEPMDDCDP_175 (original name was: gnl|Prokka|EPMDDCDP_175)

Compact view

gnlProkkaEPMDDCDP_98 - Region 1 - ranthipeptide

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Location: 1 - 15,576 nt. (total: 15,576 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaEPMDDCDP_147 - Region 1 - NRPS,cyclic-lactone-autoinducer

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Location: 33,643 - 84,797 nt. (total: 51,155 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 33642 - 84797:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Cys) + (Cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg132_39

Search NORINE for peptide: strict or relaxed

AMP-binding (25..431): diOH-Bz

nrpys: diOH-Bz

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVLSK
Nearest Stachelhaus code(s):: diOH-Bz PLPAQGVLCK (79% 8Å match); Sal PLPAQGVLNK (74% 8Å match)
Stachelhaus code match:: 90% (moderate)

ctg132_40

Search NORINE for peptide: strict or relaxed

AMP-binding (553..948): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSMIWK
Nearest Stachelhaus code(s):: Cys DLYNMSMIWK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg132_42

Search NORINE for peptide: strict or relaxed

AMP-binding (524..918): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code(s):: Cys DLYNLSLIWK (91% 8Å match)
Stachelhaus code match:: 100% (strong)