LOCUS       gnlProkkaLDKICEMA_24   16905 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LDKICEMA_24.
ACCESSION   gnlProkkaLDKICEMA_24
VERSION     gnlProkkaLDKICEMA_24
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 01:44:53
            Original ID  :: gnl|Prokka|LDKICEMA_24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16905
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16905
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3869:11905]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3870..11905
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16905
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16905
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(2..376)
                     /locus_tag="ctg21_1"
                     /transl_table=11
                     /translation="MTKYSSEFKAKVVQEYLSGRLSYKSLCTKYSIPSPKPVREWVKQA
                     QVHGLESLQRKHTKTFYSLEQKLAVVDYYQTSGEGVASVAAHFGINASQVTVWAKIFRT
                     EGVAGLRPKPRGRRSTVKHKK"
     CDS             complement(471..1826)
                     /locus_tag="ctg21_2"
                     /transl_table=11
                     /translation="MKAKDNQADRGDQPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLPKSGVNTDKLDALERFVRHFDKEYATQTVRDIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPIEMICCFVGAGIGNWLREIMIRRNWTLLACIGVSVAVACLVYFIAF
                     RGLEMGLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMVVHLRPENFVDLGLSPVLLLVYRLIASFCGVFGFSVMFNSPRRMAIQAGL
                     IGAVANTLRLELVDLNTIPPAAAAFIGALVAGLIASAINRVDGYPRISLTVPSIVIMVP
                     GLYIYRAVYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRQSD"
     CDS             complement(2006..2359)
                     /locus_tag="ctg21_3"
                     /transl_table=11
                     /translation="MDYEEELETKGYIDCLLHELHEQPQLIRQTNIEEVVERTKEEIIR
                     DGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDELRRIANGQKKEDPRRFLRI
                     WRFLAQRFQHHMQ"
     CDS             complement(2478..3857)
                     /locus_tag="ctg21_4"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLPNRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQSYHVKASASGVLHLETALEGNQYV
                     PSGSVLARILSDLSEQTDADLKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQALYYGLAGQASVITGTKTYWDYFADKMFNY
                     R"
     CDS             complement(3870..6062)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 310; E-value: 5.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_5"
                     /sec_met_domain="Peptidase_C39 (E-value: 2e-41, bitscore:
                     133.8, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1108.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQADMQLFDFEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQ
                     LQQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKL
                     QMARVANNRLNEVYLVESEFKEQRHLTERHLIEGPLRVRDVSFKYGFGQGVLKNVNLEV
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVP
                     QDPFIFSGTVLENLTLGSRSDVSEQDLTQACLVAEIAADIANLPQQWQTKLSESGSILS
                     GGQKQRLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIA
                     AKTEQIVVMDHGKIVEQGDHATLLAQDGYYARLVHE"
     CDS             6692..7987
                     /locus_tag="ctg21_6"
                     /transl_table=11
                     /translation="MTVASNITYFFITFPIFATGIYFLTVIFDSRFRVIHITFWSIFGT
                     LLSLLLSTYGEVIFFIIYTCYIVKTTSRSNIFWIFIFMEANLVVITIQSSITQALISAK
                     AHLEPWTLISDSVINLAIIIAIFWLLSNKKEQILKLRDLVQEQNKLQHSVLIYTGATCA
                     SLYCFEATWELIDLNNFLSWLSLGVFLLSVVISLYSIFFILKSYKYYIELIWIKRAESS
                     QRAYYATLAQQQKRTDKLLHDYKNLLATLQLSMDQSTHDISSETRDVVSKAQQALSQVE
                     VNQETFDAIKSDSLKSLLYLKWTEALHQNIKMYVHIEGIIEPLDSSTSFAVIRALGILI
                     DNALEETSRSGNSKFSVLLINSSSYLEVNVINDVTAGFELSNLNQPGFTTKGHGRGKGL
                     TIINELIEQNKKISLKKKVKDNQLKITLFVWR"
     CDS             7992..8768
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MSKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLATIDWSAINDSIFLLDIELGDSATSGVDVATAIRKKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLD
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVLRL
                     DITNRFVYMDNQDKLEVSIRRMGELRNILTGTRALS"
     CDS             complement(8887..9147)
                     /locus_tag="ctg21_8"
                     /transl_table=11
                     /translation="MNLYYATWLIFLATLFVFKDRKFVKRMISAILDDGNLGFGIRIVI
                     WLALLGLFFVTNHTDWPSAVLILLIVSAVILIDWHKTFQEE"
     CDS             complement(10617..10916)
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MNKLKWFAGGNERAEQAIQLIDELLRDFDDSSSHSDRLRTVLRNN
                     REALIHKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             complement(11094..11252)
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLVIPVAAILGFLATDAWSHADELVAGV
                     KQGWERS"
     CDS             complement(11720..11905)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_11"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.7e-08,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEMVDKFKGN"
     CDS             complement(11965..12150)
                     /locus_tag="ctg21_12"
                     /transl_table=11
                     /translation="MTTRTRLALKEISEEKLEMTTGGNVPLSNCSVDPPNERHPPAYEA
                     AFKYKLPIVHPIKVAT"
     CDS             complement(12542..12727)
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="MPTRLTKLVDYGLIIATIIFAIYTVTSAIGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKKA"
     CDS             complement(12777..13583)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_14"
                     /sec_met_domain="Abi (E-value: 2.1e-14, bitscore: 46.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYTLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQAIVLKVTLRRPRLKPVVIWGLLLMLIGWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGGLIRAFYVAHHRHAKYQLLFCVGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEEFLARLSHS"
     CDS             complement(13904..14344)
                     /locus_tag="ctg21_15"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNSKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKISSTLKKSGILTSKTGLNGGLRLAKTPQTITVYEILTAIEGTAPLFKLHQGIDPAAF
                     VNGERVTSWLAASTNVLNQAEDAMVQVLKQTSIADLAEAAEA"
     CDS             complement(14399..15826)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 326.4; E-value:
                     3.7e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_16"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQVIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAVQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAVRYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPILTLLISAVLWVAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSRVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTASLSKIADVFGQAMLIGVGMTIV
                     GLILVVALIIPAEKAAK"
     CDS             complement(15999..16331)
                     /locus_tag="ctg21_17"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKQAASGGLMETEAQEVVDEALDILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
ORIGIN
        1 gtttcttgtg tttcactgta gaccgccttc ctcgcggttt cggacgcaac ccagccactc
       61 cttcagtcct aaagatcttt gcccaaacag tcacctgcga agcgttgatc ccgaaatgag
      121 cagccaccga tgccacacct tcaccactgg tttgataata gtctaccacg gccaacttct
      181 gttccagaga ataaaatgtc ttcgtatgct ttcgctgaag agattcaagt ccatggactt
      241 gggcttgctt aacccactct cggactggtt tcggtgacgg gatactgtat ttagtgcaaa
      301 ggcttttata ggagagccgt ccagaaagat actcttgtac aacctttgcc ttgaactcac
      361 ttgaatattt agtcataaaa atgccccaca atcgttagag tatctgtcta acaattatgg
      421 ggcacttcat ttgaagtggg gttatttgtg ttgctaaaaa gttatactga tcaatcgctt
      481 tgccgccagc gagaatccat aatcaagcga gcggtaaaca agcccagcgg taaaaacata
      541 atgataagtg cggcacgcgt catccattcg gcaccgacgc caatattatt caatccaata
      601 ttgtaaactg cccggtaaat atacaagcca ggcaccatga tgacgatgga tggcactgtt
      661 agcgaaatcc gcggatagcc atcgacgcga ttaatcgccg acgcaatcag tccggctacc
      721 aacgcgccga taaatgccgc cgcagcaggg ggaatcgtgt tgagatccac caattcaagc
      781 cgcaacgtat tcgccactgc cccaatcaac ccggcctgga ttgccattcg gcgggggctg
      841 ttaaacatca ccgagaatcc gaagacccca caaaagctgg caatgaggcg ataaaccaaa
      901 agaaggaccg gactcaaacc taagtcgaca aagttttccg ggcgtaaatg gacaaccatc
      961 gcgaccagcc agccaaccag cgaagccaca atggtaatca tcaacgcata cagtagtcgt
     1021 tccattcccg agcgcatatc ctgcttcgaa atgtccagca tactggtgat aaacgggaaa
     1081 cccggaatca caaacaacat ggcgccgata taccccgctt catgccgcgc tgcaataccc
     1141 agtcccattt ccagtccgcg aaaagcaata aaataaacca aacaggcaac cgccacactg
     1201 acaccgatac aagccagcag tgtccagtta cgccgaatca tgatttcacg cagccaatta
     1261 ccgatccctg caccaacaaa acaacagatc atttcgatag gaccgccgcc tagcaaaaag
     1321 acgaaagcgc aacacgccaa ggctgctgcc aatccggcgc gcaacggatc gtaattgcca
     1381 gacatttttt gaatttgatc aagtcgatgg tgaatatccc ggacggtttg agtcgcatac
     1441 tctttgtcaa aatgacgcac aaaacgttcc aacgcatcca acttgtcagt attcacaccg
     1501 ctttttggca gtgaaagcac ctcagaatag gcatggttat tgctaaagca ggtatacgat
     1561 aaggaaatta ggccaatatc tgctgagcac gacatccgca atgctcgagc aacggtgttc
     1621 atcgcctcac gcacgcgcca cgccccggta ccacacgcca gcaacatgat cccgactcgg
     1681 ccgacaagtg acgcgcgctc ttcaagggtg gcatgatcgg cttgtcgctc ttcgctgaca
     1741 atcacgtcat accacgggat ctgcatatga tgtttttctg aaagcggttg gtctccccga
     1801 tccgcttggt tatcttttgc cttcataact cgtgctaatc cttcttctta tagggattgt
     1861 ctttttcaaa aaaattgaaa ataaacattc actattctag cacaattcat aacagggtgt
     1921 atttttgact ttttgaaact aacggatttg accgccttat tcatgacaag catgcacaaa
     1981 ttagcaatca tttctcggtc tcaacttatt gcatatgatg ttggaatcgc tgcgccagaa
     2041 aacgccagat tcgcaaaaag cgacggggat cttccttctt ctgtccattg gctatccgtc
     2101 gtagttcgtc aattgcatcg cgaccttctt gactcaaccg tacactttca gtcgtgagga
     2161 taaaatcaat tcttagtatc atccgaaaaa catgtcgtcg taattcatag ccatggaaac
     2221 catcgcggat aatctcttcc ttggttcttt ccacaacttc ttcaatattc gtttggcgga
     2281 tgagctgcgg ttgttcatgt aattcatgca acaggcagtc gatatagcct tttgtttcta
     2341 attcttcctc gtaatccata cgccgatcac cgcctttcat ttgactaact tgatccgcat
     2401 cgttttttta tggtcatttt cttaaataat gggcatcgca ttttcgctac taaacgacaa
     2461 aagcggtaaa taccgattca tcgatagtta aacatcttat ctgcaaagta atcccaataa
     2521 gtctttgtgc cggtgataac agatgcttga ccggctaatc cataataaag ggcctgccgc
     2581 tgcgatttag ataatttcac ccgcgccttg accgtaaaga agttgccaac tttcggatcg
     2641 cgtgtcgggg cgacgtcaat cgcataaacc cggccatcta atatggtagg ggtcggcaca
     2701 ttctcagcaa ttcgcaggcg tactttctgc ccacgcttga tgctcatgat ttctgtcggc
     2761 gaaacaccca attttaagtc ggcatccgtt tgttccgata agtccgacag aattcgtgcc
     2821 aacacgcttc ctgaagggac gtattgattc ccttccaagg cagtttctaa atgcaaaacg
     2881 ccactggcac ttgctttgac atgatagctt tgagtttcat cattcaaggt agctaactta
     2941 gcctcgtctg cttggacctg ttgttgaacc ttcgtctgtt ccgcaacggc tgtttgctgc
     3001 aaccgacttt gtaatgcggt tagattagcc tgagtctccc ccgctttttg agccgataca
     3061 tctgcttgtt tttgaccggc ccgttgctgc tctaaagacg tcaaattggt ttgttcctca
     3121 tccaactgtg tctgtaattg agcaaggtac tggcgtttaa ggttcgcctg tgcctccgcg
     3181 tcggtatttt ttatctcact ttcatattgt tgataaaggt agtgataggc gtggcgattg
     3241 ggcaagggtt tgttcgcctg aatcgccgct tttgcctcgg agatagcggc catttttgct
     3301 tggctcgttt ggatactggc gcttagtaac cgatcaatct ctttgttttt ttcactagcg
     3361 acggtttggg ttgcctgctc agcctctgct gtcagtgtca gcactcggcg ttgactcaga
     3421 taatcttgca cctgttgttg atagccgaat cggtctgcct ttgaaaaaag atctttgttt
     3481 tcggtaacac tttgtttcaa aacatccaat tgctgctgtt gctcttttag cgttgccagt
     3541 tgctgcttga gtaatttaat ttgtgttgga ttggcgacat cgtggtaaac aagtaaggtc
     3601 tcgcctttct tcacgcgctt gccttctttc atgcggttcg agacgatccg attggcggcc
     3661 gtcgcctgaa ccgtcacggc tgcctttacc ggttcaattt cggcagctgt cagcacagtt
     3721 acctcgcgcc gagcaaagat cagaaacaat agcaagccta agaaaagaat cgtactaggc
     3781 ataataatca ttgttgaaaa attgcgaaag cggtgctggt aatattcggt cgttgcaagt
     3841 tttttgggat ccatcatcta aagctcacct cactcatgaa ccaggcgcgc gtaataaccg
     3901 tcttgggcta acaacgtcgc atggtcacct tgttccacaa ttttgccatg atccatcacc
     3961 acaatttgtt cggttttagc cgcaatggtt aagcgatggg caacaaaaat aatggtccga
     4021 tccgtcattg ccagcaagcg atcgacaatt tttcgctctg taatggtatc cagactgctg
     4081 gtcgattcgt caaaaatgag tacttttgcc ggtgataaca aggctcgtgc aatcgccagc
     4141 cgctgcttct gaccccctga taaaatgctg ccgctttctg acagtttggt ctgccactgc
     4201 tgcggtaagt ttgcgatgtc tgcagcaatt tccgcaacca aacacgcctg cgtcaagtct
     4261 tgttccgaaa catccgaacg gctacctaac gtcaaattct ccaacaccgt ccccgaaaaa
     4321 ataaatggat cctgaggtac atattcaata tattgccgta atgttgtgag attaatatct
     4381 ttgaccggaa taccattaaa cgtgatggtt cctttatcgg catcaaccgg gtaaaagcca
     4441 actaataatt ttgctaatgt cgacttacca gaaccgctca tgccgacgat ggtatattta
     4501 gcattttccg ggacttcaag gttgacgttt ttcaacacac cttggccaaa accatattta
     4561 aacgaaacat cccgaacgcg taacgggcct tcgattaaat gccgctccgt caagtgccgc
     4621 tgttctttga attccgattc aaccagataa acctcattca aacgattgtt agcaacccgc
     4681 gccatttgta actttggctg taggttgatg atgctttcaa gcggattcgt aaagtatgac
     4741 agcagcgcat taaaggtcag catctgcccc aaactcatcc gattggcaat caccaaactt
     4801 gccccaatcc acaacaccac aacgttcaac gccagcttca acagaccttt aatcgcttgc
     4861 tgtaattgat ctgccttagt gtaactaaac gatttcttca gataagttag aaattcccga
     4921 tcaacccgtt catagctaac tcgttcgccg gtcagggact tgatggtttc aatgccattc
     4981 aaatcttcaa taatcgatga actcaagatt gcgttacttt ccatcgtctc ttggttcaac
     5041 cgatcaaacg gccgctgaaa tgcaaaaaca atcaccaaat aacacggcac ggcaatcaat
     5101 gacactaaaa acaaagtccc attttggatc cctagaacaa tgcctaatat taggacaatc
     5161 cagacatcca aaaataacgt cataatcgta ttcgccagcg catcaataat tttattcgcg
     5221 tccgcaaacc gcgacacaat ctctccggtc cgccgagttg aaaaaaacga catcggcaat
     5281 tcatataaat ggcgcacata ccctaaaatg acatcaatcg caagtcgctg ccccaacacc
     5341 gccatcaaaa aattctggcc ataagtcaac acagcttgca gcaagtaagc caccaaaagg
     5401 ccactagcaa tcatccccat cgtcgtccgc atggcattcg gtatatacgt atcaataata
     5461 gactgcaaaa aatacgaccc aacgatacta atgaccgtaa tcaataccgc ggccagaata
     5521 atgttcgcga tgatgccttt ctgcttagct agcatgggta caaacgcaaa caaactgcct
     5581 ttgtcctcct tacgcggctg atactgcggc gccggtgcaa taaagatggc cacacccgac
     5641 cattcttttt caaacacctc tcgcgaaagc caggtcatgc gcactgacgg gtcaggatcg
     5701 ccaatcagaa tactcgtgcg cgttgcctta aaaacaacat aataatgaag caattcacca
     5761 cgcttcagca catgggcaat aaacggataa ggcacatcct caaaatcaaa caactgcata
     5821 tccgcctgca ccggtttcgt ctcaaacgct agtgcttcag cggcccgaac aattcccaaa
     5881 gcagtcgtgc catcctgatt tgtcttcgct aactcgcgca agtgggctaa cgaatagtcc
     5941 gacccattgt atttaagcag catgtttaac gcagccacac cacagtcacg ctcgtcaact
     6001 tgtgcggtgt agaagcgttt gtagtaggtg atctggccta gttttggggt gtatttaacc
     6061 attaactctc ctcgcttatt aagccattag attcaggcct cttttatgaa cttatatgtc
     6121 aaaacagtta gccaaagata caggtgaagt atcgcaaact tttgcttaac agctttgatc
     6181 taagtgtcgt aagatttagt tttttgcatt taaaatatgt ggtagtatat tttaaagcag
     6241 ataaaatagc atataaaaat aaatattcat tttaaaagta cttttatatt taaatattta
     6301 ttcttatatg cttaaagcaa ttatgtgctc agctttttca aaagacgtat atggctttaa
     6361 tgctttcttt gaaactgttc tatcagccat ttttttatat tttcaaacgc ttggcttgtt
     6421 ggtcgcaaat tgccaccatg tatttgtacg agccgctcat ccgaaatcac gctgtttttc
     6481 atctgactct gaaacccctt tttgttgttc acttcaaact acctcctatg atttattctt
     6541 ctgtttttaa cctaacatgt cgtgagcttt ttggggcata caaaaaataa acgtcgtgtt
     6601 ttggccattt aacgtcattg tgtcagcaga tgacgtcatt tatcttcatt caaaacttgc
     6661 catactttca taacttgcgg aggttttcta tatgacagtg gcgtcaaaca taacctactt
     6721 ctttataact tttcctattt ttgcgactgg aatttacttt cttaccgtca ttttcgacag
     6781 ccgtttcaga gttatccaca tcactttttg gtcaatcttc ggaacccttc tgtctttgct
     6841 cctttcaact tatggcgagg tcatattctt tataatctat acgtgctata tagttaagac
     6901 cacttcacgt tctaatattt tctggatttt tatctttatg gaagccaacc ttgttgttat
     6961 cacaattcaa tcctctatta cacaagcctt gatctcagct aaagcacacc ttgagccttg
     7021 gacattaatt tccgactcag ttattaactt ggcaataatc atcgcgattt tctggttact
     7081 ttctaacaag aaagagcaaa ttttaaaact gcgcgaccta gttcaggaac agaataaact
     7141 gcaacattca gttctgatct acacaggcgc aacctgtgcg tcactatact gttttgaggc
     7201 tacttgggag ctaatcgatc tcaacaactt cttatcttgg ttaagtcttg gcgtattcct
     7261 actttcagtt gtgatcagcc tttattcaat tttctttatc ttaaaatcct ataaatatta
     7321 tatagagctc atctggatta aacgggcaga aagttcccag cgtgcttact atgcaacgtt
     7381 agcacagcaa caaaagagaa cggacaagct ccttcatgat tacaaaaact tattagccac
     7441 gttgcagttg tcaatggatc aatcaactca cgacatttct tctgagacgc gagacgttgt
     7501 ttcaaaggca caacaagcgc tatctcaagt cgaggtcaat caagaaacct tcgatgcaat
     7561 taaaagcgat tcgctgaaaa gtctactcta tttaaaatgg acagaagcgc tacatcagaa
     7621 tatcaagatg tacgttcaca tcgaagggat cattgaaccg ctcgatagca gcacttcatt
     7681 cgcggtcatt cgcgcactcg gtattttaat tgacaacgct ttagaagaaa caagccgctc
     7741 cggaaactca aagtttagtg tcttattaat caattcaagc tcgtacctgg aagttaatgt
     7801 catcaatgac gtgaccgcgg gatttgaact atcaaatctt aaccagcctg gatttaccac
     7861 caaaggccat ggtcgcggaa aggggttgac cattattaac gagctgattg aacaaaacaa
     7921 aaaaatcagc cttaagaaaa aggtcaaaga taaccagttg aaaatcacac tttttgtatg
     7981 gaggtaactt tatgtctaaa aacaaaacga tcctaaacat ttatattctc gaagacaacc
     8041 ctgactatct aacctttatc caagaaactg tgcagcagta ccttctgatt gaagaactac
     8101 ccgccaagat ccggctggca acaacgtcag caaccgaact gctcgcaact attgattggt
     8161 cagccatcaa cgatagtatc ttcctccttg atatcgagct gggagattca gcgacaagcg
     8221 gcgtagatgt agccacagcc attcggaaaa agtcatatta tgtcgatatc ctcttcatca
     8281 ctagccatgt agatgaagct ttaaggattt tagagcacaa aatcgcaccg ttggacatga
     8341 tcaataagaa ctcaccttcg aagacagaaa agaaaattcg aaataacatt ctttatgcaa
     8401 taaaacggct aaaggcgcgt caggtcgcat ctcccagatt gtttagctac agcatcaact
     8461 ccagcatttt ttcacttgat atggatgagc tcatctatat tcaaactgct cccggtgtct
     8521 cagggacact ggagcttcat gcagaaaatg aaatcacaac ctttcccggc aaccttaagg
     8581 aactagcgac caaatatacc aacttatgtc gatgccataa gagtatcctg attaatcccg
     8641 cacatgtttt gcgtctggac atcacaaacc gattcgttta tatggacaat caagataaac
     8701 ttgaggtcag tattcggaga atgggcgagt tgcgcaacat cttaacaggc acacgggctt
     8761 tatcttaaga agagtgtgac tgggcaatca tcctagattt ctgttaatca acacagctga
     8821 acgcacaaat aacgcatcct caatatcaag ggtgcgttat ttggtggttt atacaggttg
     8881 gaaatactat tcctcctgaa aggttttatg ccaatcaatt aaaattactg cactaacgat
     8941 gagcagtata aggactgccg aaggccaatc agtgtgattt gtgacaaaga aaagccctaa
     9001 aagagccaac catatgacaa ttctgatacc aaatcctaaa tttccatcat ctaaaattgc
     9061 ggaaatcatt cttttgacaa atttgcgatc tttgaaaaca aacaaagttg ccaaaaagat
     9121 aagccatgtt gcgtaataaa gattcacagt gctactcctt catcagctct acttcaacca
     9181 acgcgctatc gactgacccg tttgataacc agcgtcataa atccccttta aaattcccgg
     9241 tgaaaagtac caaaacgaca ttattaaaac cccaatggcg acaagcaacg acactttctg
     9301 ttggaatgat aatcttgcaa attgatcgat tacgctcacc tcgtttacaa acagacttat
     9361 ttttacttct ttcagcaatc cattagtaac ctgttcttta tgttctccca ccttctaaga
     9421 aaaaggcaat atactaatgg ccaactgcat caattgggaa catttctccc aaaaagatgt
     9481 tcgcgcatga agccgatgtc ttaagaggtc tatcatctgc cagctgatcg cagttacaaa
     9541 tacgaatgtg aagaaaaatg ccagaatcaa aagcatagaa tataacacaa ctgtcataag
     9601 caaagctcct tgagtcttcc tttaaactta cattgaggcg gcaaattagc gagcacaggt
     9661 tcggagatac tatacgttct gctagggtcg gtcatacaag caaggagtca caaaaaatga
     9721 caccatttta gctatttaat gctgtttcct aaagcccttt tgctgtcagg gaaaaaacaa
     9781 ttgttggttt tgaaagctca tcttgtttag catctgttct gccatactca cgcgcaagat
     9841 ctcctgattt gtatttttgt ttcaatacaa atcaggagac cttttgcggt ttttggctga
     9901 tagaacatag ggtaacaaga ttctgacact aaaagcagtt tccaaatatc agtagtgtca
     9961 cctaaaatct catttgccgt catgaacagt cgacattgca ttattatggc ctggcagata
    10021 gctgtgtcac aatagttgct gtctctcggt gctgacaggc ttcctactga caatgacgct
    10081 gccgccttac caatacttcg aaatcaaaca aagaaaattt gttatttaga gcgtttatga
    10141 tctttaaccc ttgaagatgc gacacttatt ttagaaaaaa gaatcaaaac aatgaagatt
    10201 gaaagcatct caatgaacgc ccggacgatg aaaaaatcaa aacccaagca atcgacaatc
    10261 agcttgttta agctatcact gagcgagaac ccgccgaaaa agatacaaac gataatccag
    10321 aaagaagctt cattaagcca tgtgtgcata gttttaagaa tcgtcatcgt acctccgctt
    10381 tgctcatcac taaatcattt atcgaccgat cagttttggc tctgtctttt taagttagac
    10441 cgttatattc gaaactagtt tgccaaagtc gccgttataa attggacaac cttttaggca
    10501 tcatccattg acaacaagcc cataccaacc agcatcgcaa tcggagtttg atctgcacca
    10561 aatgaatcag tgaacctaac cataatcaag cgcgctcacc gttttagtag tggcttctag
    10621 tacccatatc tgatattcgc cagcgaagaa agctgctcga atttatcaga ttgttgcttg
    10681 gttaacaaaa tattgttttg caacagggca ttagagattt ctagattcat gcggcttaaa
    10741 ataaatggaa ccgctgcttg cttgtgaatt aaggcctctc tattgttcct tagcactgtc
    10801 cgtaagcgat cactatggga agaactgtca tcgaagtcgc gaagcagctc atcgataagc
    10861 tgtatcgctt gttcagctcg ttcattcccg ccagcaaacc atttcaattt gttcatcatt
    10921 cactccaaaa aacgttgtgc ttgtgcatct tcacttgtaa cacgtttggc gccgtgcatt
    10981 gccagatctg ccgtagcaat aacggtaagt gcgtgctcgc ccacagataa aaacttgttc
    11041 tggggagaga tacttttaca acggcgaaat cgctaaaaat caacgcaccg ttattacgat
    11101 cgttcccatc cttgcttgac cccagctacc agctcatcag catggctcca cgcatctgtt
    11161 gccagaaatc caagaatggc agcgacaggg attacgagcg gtccgatacc gccggaaatc
    11221 ttactcaatt cagcttcatt caacttagtc attaaaatta cccccttgta tttgtagaaa
    11281 ctactcgcca gttgatccaa aagtccttgt tatggatatc gtggcgataa aacactcatc
    11341 aaccgcacaa ctttttgcaa atacaaccat tgagtcatca tcggcatgcc tggattaagg
    11401 ccacttgacc ttcaccatcg aaattcgact actggatttg tatggcagca ttacagcgta
    11461 cggcttaggc attgaacgga acactcaaag tttaagcgta ggtaataaac cagatggcat
    11521 tcaaaatata agcacgttta aaggctatct gatgcccact gtcgagatat ttatcattcc
    11581 caacgcgata gtgaccatct tttttacagc acgtatatac caaaacacct aatagatata
    11641 ccaagataaa cgtagctaac attaaaagat ttatcttatt catacgttcg cccgttcgag
    11701 tgcctattca tcgcggatgc taattgcctt tgaacttgtc aaccatctct ttggcaggac
    11761 caatggctgg tgcaaacatg gcgccttcag cccaagaacg cgcggttgaa ccaatagcct
    11821 tcccgataaa ggtccacaga ttaccattat cgccaccaga aatgcttgct aagtcagctg
    11881 tgtttaaagt ttttaaatga tccatgtttt tcctcctttt ttctttatga gcctgtcaat
    11941 gtattaatca gcccaggtta ttgcttaagt cgccacctta attggatgaa caatcggcag
    12001 tttatactta aatgccgctt cgtaagctgg cggatggcgt tcgtttggtg gatccacact
    12061 gcaattggat aaaggaacat tcccaccggt cgtcatttca agcttttctt ctgagatttc
    12121 tttcaaagct agccgcgttc gtgtggtcat cccatttttc tcctttccct ttgttagaag
    12181 gacttccctt cttcctcatc aatataaagt agacagccag gtttgtggga atgaattttt
    12241 taacgtcgat ttttgcaaga aaatcgtcgt aaaaaaccta attttgacgt ttatcgttaa
    12301 aaacccggcg attatttgat attgccgcct tctcttcaaa actcaagcaa ctgcaactgt
    12361 aactgtattt acttttaccc atgtcttttt cgccactgtg agcatccagt cttaagccaa
    12421 cttagaaagg cgatcaggct cgcggccagc atgtgcatcc attcaccggg aaagtgataa
    12481 caaactgcac acatataacc gacaaaaaat gttaataaac agcgccaaaa tcttttttga
    12541 ttcacgcttt cttctgcttt tcctcccgct cactcaacag catcaacaac gtcatcaaaa
    12601 tcaacattgg cgtcacaaaa ctgccgtgat tggtccaccc aattgccgat gtgaccgtat
    12661 aaatggcgaa aataatggta gcgattatca acccataatc gactagttta gtcagtcgcg
    12721 taggcatcgt ttttctcctt aaactcgttc tatcataatt gatacagaca gccgcgctac
    12781 gaatgcgata accgtgccag aaactcttca ttgttttggc cacggcgaaa aagtcgcagt
    12841 gcaatcgcta ggtaaatccc ggcaataagg aatgcgtgaa caatcgtcat cgttatagcg
    12901 ttgggatcac taggcgcttc tttcggatac ggtccactaa ccaaagtgat aacaaaatca
    12961 atcaaaaaat ggatcaatat tggcataagc aacgatccgt agcgaatata aagtgctgca
    13021 aaaatagccc ccatgccaaa tgcctggatc acttgggcaa ttgttatcac aagcccttga
    13081 gcaggcaaat tactcaggtg agccaatgaa aaaaccaagc tgcttaaccc tacgcaaaat
    13141 aagagttggt atttggcatg gcgatgatgg gcaacataaa acgcccgaat caaaccgcca
    13201 agcatgacgc cacgaaacaa atactcttct ggaacagcgg caatggtacc aatcacagct
    13261 gcttgcaaga cgtcaatcgg tgttcgattt gtaaccgtga accacccgat aagcatcaag
    13321 agcagtcccc agatgacaac cggcttcaat cgtggccgcc taagtgtcac tttcaagacg
    13381 atagcttgtt tcagcagcag ccagttaagt gcgatcatca ccagtaaaat gatggcttta
    13441 aataagatat tcccagccca gaagtccaat ttcagcgtgt aaactgctgg aattaaaagc
    13501 agctggctga ttagcacaac caaaagcaag atatataaaa cgcaaaatcc tggcgacaat
    13561 agcaaatgac gttttctttc catttattca ccttcactcg cacgtttcaa tgcaaagcag
    13621 cttcgatatc gctacccaca atataccgag tcttcgcatg ttacggatca ttaactttta
    13681 aacgtcgggt tttcaccgat aatcgttgtg ttttgaaact tgacaacgcg ttaatcgtcc
    13741 ccatttccga aaaggtcggc aaatggaggc gcacttgctg actatttact gactgcccca
    13801 cagttgcacg atcctgaaaa tgccgtaagc aaaatcgcct catccaatgc caacgcgcca
    13861 acgtcagtct tggatgaggc gatgaaaagt tagagttcga tatttacgct tctgcggctt
    13921 cagccaaatc agcaatgctc gtctgcttta gcacttgcac catagcatct tcggcttggt
    13981 ttaaaacatt ggtgcttgcc gctaaccagc tcgtgacgcg ctcgccgttg acaaacgcag
    14041 ctggatcgat tccctgatga agcttaaata acggtgccgt cccttcaata gccgttaaga
    14101 tttcgtaaac tgtaatcgtt tgtggcgttt tggctaatcg caaaccgcca ttgagaccgg
    14161 ttttcgacgt taaaatacca ctttttttaa gtgtagacga aattttttta atgctaggaa
    14221 ccggaatgtt tagcatttcg gaaatctttt gaattgataa atagtcttcg tgttgtgctt
    14281 gggactttga gttgacataa gccgtaattt caagtgcttg cgagaatgcg actgaaaaag
    14341 ccatcgaata tacctcccat taggcgattg tgtatattct attataccaa tgataccgtt
    14401 acttggcggc tttttctgcc ggaataatga gcgcgacgac aagtattaag ccaacaatgg
    14461 tcatgccaac gccaatcaac attgcctgtc cgaatacatc ggcaatttta gataagctgg
    14521 cggtcgaggc cgcaaaaatt gccagtccta aagcgccgcc aaattgtcgg gcggtgttgt
    14581 agacgcctga tgcagctccc gaaatttccg gccgaattct agccaaacct gaagtagcga
    14641 gtgtggcaaa tgccagcgcg aatcctaccg caaatccgag tgttccgagt aacaaaaacc
    14701 agtaattggc aaaccgtgat gccactgcca gttcagccaa tgaaagtagc accgtgacaa
    14761 atccgaagat catgaccctt gagttacgcc accgatcaac gaaggtccgg gccttgactg
    14821 ccacaatgaa cagtaggatg gccattggca ccatgcctaa cgcagtcata aatggcgtta
    14881 atcctaagac gccttgcata aactgaggtg tgtagaacca aaagccgatt gcagcggcac
    14941 taaacaacag agaactgaca taagaagcca tccgttccct atccgtaaag atttccagtg
    15001 gcattgtcgg gtgggcaacg cgaccttgac tagcaatgaa tgcaacccaa agaactgctg
    15061 aaatcagcaa cgtgaggatt ggccatggac tgccatctaa cccatatgag attgaagtca
    15121 tcgctaatac tgacaagatc gtaccaatcc agtcaatctt tccggtttgg cgttttgcac
    15181 taggtaaata tcttaccgca ataccaacca tgattaacgc gatcggacca ttcatgtaga
    15241 aaccgacccg ccatgacgca aatgttgcaa agaagccgcc aatgactaaa ccaaccgctg
    15301 caccggctcc aatcacagag gcgtagtagc caatcgcccg ctgccgtgct tttccttgaa
    15361 aggtgtcggt taacaatgct aaacagttcg gtgcaagaat ggccgcgccc acgccttgca
    15421 cagcgcgaaa gctaatcatg acaagcgcat tagtagctgc cccgactgcc agactgccaa
    15481 ccccgaaaat agctaaactc gcaatgaata atggcttgcg tccgtatata tcgcctaatt
    15541 taccgcctac tagcatcagc ccagcataag ttagcgcata ggccacctgc acccaagaca
    15601 acgcgccagc attcaaatgc aattgtaccg ccattttgac ggtacctgtg taaacaatcg
    15661 atgtgtcaag cacacctaga aaagccccaa tcagtgccag acctaaaata atgacttgag
    15721 tcgctgacat gcgctgcgat tgggtgattg ccgcatctgt ttcctcaatg acggtgtcgt
    15781 cagccaggcc atcattgatt aattccttgt cttcttcttt gctcatatga gatgcccctt
    15841 tctatggttc acttagtata ttccgtttat actaatatgg caaatctttt ttgagcaaaa
    15901 aaaccacgtg ttccttaatt ctgtggaaac acgcggctac aagcgaattc ttttcgggcc
    15961 ggttactgga atcagaccat ggcttgggca acaactgtct aaataataaa gtgcggcccg
    16021 cctacctgac tcaattcgcc atgaatgtca ttttccataa agtcttttac cgcctgccac
    16081 cactgattgg cctctgctga aagtttcatt ccttgcaagc cgattaatcg cgtaaaccgt
    16141 gcgtatagtc gcgacaaggc gtaatctgcg gctcgattct tgagcacatt aggccgcttt
    16201 aaaatatcta aggcctcatc cacaacttcc tgtgcttctg tctccatcaa gccaccacta
    16261 gccgcttgtt tcagactcag gtttaatccg gtcaaaataa acagaatctg atttcgttgc
    16321 accatattca tgagcgatcc tccatgtctg gtagataaat gtttgcaatg agataatgtt
    16381 ttcttgaatt gctaactgca atataccaaa tctatcaagc ttcgggtcaa actttcgata
    16441 aacgtcgcct tttcgccgat taacgttatt gcggacatga atcgcccggt ccaaagcaca
    16501 tagaaaaagc cgtggtgcat taaccacgac taatcggaag cgcgtatttc agcatagtcg
    16561 taaaaaggct gaaatgacac agttcatcag catcaaacaa attcatattc catccggcta
    16621 cttaatgtcc gccaccccag acaattggaa aggcgacgag cccagcagcc agcgcctgat
    16681 cgcgataacg cttggcattg acctgatctg ccggcacatc cgccttgatc gcattgaaaa
    16741 tggcgatcat ctcgtctgga atcgtgtgat gaatgagata atacttggaa atatcatgcg
    16801 atagctgggt cacgactgcg acataagttg ttttatcctc tgcatcttcc agttgtttcg
    16861 cgttggattc gattatttgc tttaatttgg catcagcttt cacgg
//
