LOCUS       gnlProkkaHNNLDLLG_1    23225 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNNLDLLG_1.
ACCESSION   gnlProkkaHNNLDLLG_1
VERSION     gnlProkkaHNNLDLLG_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 01:46:19
            Original ID  :: gnl|Prokka|HNNLDLLG_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 927812
            Orig. end    :: 951037
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23225
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13225]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13225
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23225
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23225
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="4"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             706..1365
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 178; E-value: 3.4e-54)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_936"
                     /transl_table=11
                     /translation="MARILVIDDQKDIVQLVVKALELQNHNVTGLTSVLDLDKNSLPRF
                     DLILLDTMMPDVDGLQFCHEIRNQVDCPILFITAKTQEADIVQGLSYGADDYICKPFGV
                     KELQARVAAHLRREHRERHHKLSLGEFQFDLSAQELYIENQLLDLTKSEYGICQFLAEN
                     KGQVFSKEQIYTHLYGYEDKGSPAAVAEHIKNIRAKLKEVGQNPIETVWGIGYKWH"
     CDS             1356..2750
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 127.7; E-value: 1.2e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_937"
                     /transl_table=11
                     /translation="MALIKKREHSLRTILLSYVVSLTVLSVISSLLILYLFSLSFRFGV
                     LIPANQVESDLSAVRSDIETSKVFNPEILPDGTSYVFLTRDFKLKKSNMPVNLQEESLL
                     NYQFKNAHGEKYGYFQSFERSDGIVIVNYQLSPRYRNEWMNQHFPNADLMMIGSMFVSI
                     LIIFIILTFYYANKLSQQLKPILRVTEKISQQDLDFQTSQSTIKEFNQVLSGLDHMRIA
                     LRESLMENWKAEQDKQNQISALTHDLKTPLTVARGNAELLAMTSLDENQTDLLEHFQKG
                     IAQVDAYVKELSEFNKMSLKKTLTLEEVPVKEFVEDIYDQTLSLAQTKQINVVFDKKEI
                     AKESIGNWDKSLLNRAIMNIVSNAVEHTPSGSQLLLTARVEEDEFKFICLDSGPGFSLE
                     SLENATQLFYQEDKSRHSRNHSGLGLTIANDIIRLHYGSLSLANDNGTGGAKVTIILPL
                     LNTDDS"
     CDS             2851..4194
                     /locus_tag="ctg1_938"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
     CDS             complement(4459..5250)
                     /locus_tag="ctg1_939"
                     /transl_table=11
                     /translation="MADQKANGIDILTDGKFGRSMWHLDFVWGLKGIERYIAEHGYTFK
                     DHDGGQYETRKDIGIRITEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHAYTELA
                     IFDRLAVPGQVYETNEELKKGLINAYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPTSF
                     YSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSASEGTYEDIAKKF
                     LAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             5561..5989
                     /locus_tag="ctg1_940"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             5991..6284
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 60.2;
                     E-value: 2.8e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_941"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDASIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             6495..6836
                     /NRPS_PKS="Domain: PKS_KR (3-111). E-value: 1.4e-10. Score:
                     33.2. Matches aSDomain: nrpspksdomains_ctg1_942_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     109; E-value: 4.5e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_942"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITEEQFQRT
                     FNINIGGVI"
     aSDomain        6504..6827
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_942_PKS_KR.1"
                     /evalue="1.40E-10"
                     /label="ctg1_942_PKS_KR.1"
                     /locus_tag="ctg1_942"
                     /protein_end="111"
                     /protein_start="3"
                     /score="33.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITEEQFQRTFNI
                     NIGG"
     CDS_motif       6510..6578
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_942_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_942"
                     /protein_end="28"
                     /protein_start="5"
                     /score="11.6"
                     /tool="antismash"
                     /translation="IVTGAGQGIGFAISKRLVEDGVK"
     CDS             7112..7258
                     /locus_tag="ctg1_943"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             7646..9478
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 550.4; E-value:
                     9.1e-167)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_944"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDAIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             10001..10489
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_945"
                     /sec_met_domain="TIGR01716 (E-value: 1.8e-20, bitscore:
                     70.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDV"
     CDS             10486..10857
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_946"
                     /sec_met_domain="TIGR01716 (E-value: 2.7e-20, bitscore:
                     69.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERD
                     EYIDALYFEKQLNHSCFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCITAMKLA
                     NSENLAIKFENHLSGVLKM"
     CDS             10917..11717
                     /locus_tag="ctg1_947"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             11777..11926
                     /locus_tag="ctg1_948"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGRC
                     PPSV"
     CDS             12128..13225
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_949"
                     /sec_met_domain="PF04055 (E-value: 2.2e-20, bitscore: 70.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 7.2e-09, bitscore: 33.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.4e-10, bitscore:
                     37.6, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 6.4e-08, bitscore: 29.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQFSLKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKI
                     PLKVIQIEVTNKCNLRCMHCYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLL
                     QGLSEIIEEVLKEGMCTTIFTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRG
                     RGTFKRTIKNIEYFRSLGVPVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFER
                     NNRLSISDEEFNNAILCIPNIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTL
                     SSTKFCGGNINEKTLNDIWINSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGS
                     IGSPDIQECKLAYNLTGIKPKSMSL"
     CDS             13222..13965
                     /locus_tag="ctg1_950"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             13972..15144
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_951"
                     /transl_table=11
                     /translation="MKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             15398..17074
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 503.4;
                     E-value: 1.4e-152)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_952"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-50, bitscore:
                     168.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.6e-45, bitscore:
                     149.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALTQAVDGPVLIDVPIDYKDNIKLGETILPDEFY"
     CDS             17090..17809
                     /locus_tag="ctg1_953"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(17861..18490)
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 197; E-value: 8.6e-60)"
                     /gene_kind="other"
                     /locus_tag="ctg1_954"
                     /transl_table=11
                     /translation="MDMSGAYTPLARKLFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQ
                     FDKKSLPYRALKNHWRLFQKDSRKLSLNSFYSKTFRQTLAPHEVVAKTLVFSKELTDYY
                     TLYQLLLFHFQEKRVDEFFELIEENRSKVNHYFQTVFRTFLRHKQYIKNALETDYSNAK
                     LEATNKLIKDIKRLGFGFRNFINFKKRVFITLNIHKKRTYPALSRY"
     CDS             complement(18532..18732)
                     /locus_tag="ctg1_955"
                     /transl_table=11
                     /translation="MSTSTVYRKLDQFTFKEHYDKLPAVMSWDEFGFKKEELAFVAQNY
                     ETIQLIAILDNRRQTTIRNYF"
     CDS             complement(19373..20077)
                     /locus_tag="ctg1_956"
                     /transl_table=11
                     /translation="MTEKGIIISEKLADLAGISVGDEVTVQNSQDKDIKLKVAGISEMY
                     MGYFIFMNESTYKDAFGKEASQNATILTLKDHSDKNVEQTASRFMSLDGVKGDVQNTTL
                     KAQIKTIVNSLSRVMGVLISVSILLAFVVLFNLTNINVAERIRELSTIKVLGFFNKEVT
                     LYIYRETICLSIIGILVEFGLGLGLHQYMVDVIPPENIMFNPNLGWLIYAVPTLVIIII
                     LTGSGYLCEPTP"
     CDS             20329..21051
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     76.2; E-value: 4.8e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_957"
                     /transl_table=11
                     /translation="MRGRVSSYLADFSKLDNVYRFVEEIKRDFQRIDILFNNAGLYAGK
                     ERKASGENVELTFMLSVLVPYIFITELIPLLEKLPDGLVINTSSYMHHFAKVKDLDFGF
                     EKEYNPGLAYNNSKLYTIWMTRYLARDFFLKGSNTTINAYHLGLILTNLGNNSSDKKTE
                     KSLFGRLMKSLSKDLDQGIETGYYLTLSEEVSGLTGYYFDEKKVKSVSEKGYSFEKTQK
                     LMNYCQEKVKMFKEKQNV"
     CDS             complement(21228..21440)
                     /locus_tag="ctg1_958"
                     /transl_table=11
                     /translation="MLLLILLGIFTAFLSLAFALLHLMASLSELRKHKNTLGNRLLLIG
                     SNLATFSHPLLPFADCCFIPLADRS"
     CDS             complement(21479..22018)
                     /locus_tag="ctg1_959"
                     /transl_table=11
                     /translation="MTAQDRRITKTRKAIYQAFLYLLNQKDYEAITVQEIIDLADVGRS
                     TFYSHYESKELLLDELCQKLFHHLFERTQYLSPQDYLAHIFQHFKKNQDHVTSLLLSKN
                     DYFIRQLRKELEHDVYPMVADELIQSHPNIPHSYLKHLVITNFIETLTWWLKKGKSYSE
                     QEVVQFYLEILNVASN"
     CDS             22152..23048
                     /locus_tag="ctg1_960"
                     /transl_table=11
                     /translation="MSSKYAVWLAFFLNLSFSIVEFIAGGIFVSSAVLADSVHDLGDAL
                     AIGLSAFLETISNREEDSRYTLGYKRFSLLGALVTAVILMTGSGMVILENISKLFHPQP
                     VNDEGLLWLGIIAISVNLLASLVIRKGQTKNESILSLHFLEDTLGWLAVILMAIVLRFT
                     DWYILDPLLSLAISFFILSKAIPRFWSTLKIFLDAVPEGVDIKQVKNDLEQLDNVASIN
                     QLNLWTMDGLEKNAIVHVCLEHVKHIEVCKESIRDLLKESGFQNVTIEVDEDLATHQAH
                     KRNIEELEAESEQQHHH"
ORIGIN
        1 tgtgattgag ggttttattc atacccataa ccggaagaaa tacttcctaa agatttattc
       61 tttagcaatt gtgatgggac tgattcaatt tggattctat aattttctac atcctctagt
      121 tagaccagat ggtttctttc cacaaaatat gatgctgtcg tcattcgcaa ttttgctcgt
      181 tgctcttcaa gggattgcat ggattcaaga aaagaaatac cttaaaggga taccaacttt
      241 actttttcca ttgttgcttc catggttaat gatgcctttt tatctgctaa gtgtgaacaa
      301 acctatgttt ggttttctac taaatttact caatttcaca gtattgccag tccatacatt
      361 tatcagtgat ggaggaacgt ggttgctttt gaccggtatc gctatgtatc tttgtcatag
      421 gaatcttaag aaagaagtgc ttgcttttat gagtgttagt ctcgtttggc tgctaatggc
      481 gattgtttta agtagacctt cttttcacga tttaatattc aaatactttg aatggatgga
      541 aatattttca gcacctttaa tgctttctta taacggtcaa agagggaaag ggtcaaaata
      601 tttgttctat gttttttacc caacccatat ttatctactt tacgccttgt cagttatctt
      661 ctatagatga tatgatatgg ataactttga aggaaaggaa aggctatggc tcgaatactt
      721 gttattgatg atcaaaaaga tattgttcaa ttggttgtaa aggctttaga gctccaaaac
      781 cataatgtga cagggcttac aagtgtttta gatttggata agaactcttt acctcgattt
      841 gacctgattt tactggatac tatgatgcct gatgttgacg gtctacagtt ttgccatgag
      901 attcgaaatc aggtggattg cccaatcctc tttattacag ctaaaacgca agaagcagac
      961 attgtccaag ggttgagtta tggtgcggat gattacattt gcaaaccatt tggagttaaa
     1021 gaactccaag cgcgtgttgc agctcacttg agacgtgaac atcgtgagcg tcaccataag
     1081 ctttcacttg gggagtttca gtttgacttg tctgctcaag agctttatat tgagaatcag
     1141 ttgttagatt tgacaaagtc ggaatatggt atttgccagt ttttagctga aaataagggc
     1201 caagtctttt caaaagaaca aatctacacg catttgtacg gctatgagga taaaggcagt
     1261 ccggcagcag tggctgaaca tatcaagaat atccgtgcaa agcttaaaga agttgggcaa
     1321 aatcctattg aaacagtttg ggggattggt tacaagtggc actaataaaa aaacgagaac
     1381 actctctaag aacaatcttg ttatcttatg tcgtcagtct tacagttctc tctgtaatca
     1441 gcagtcttct tattttgtat ttgttcagct tgtcttttcg ttttggagtt ttgattccag
     1501 caaatcaagt tgagagtgat ttgtctgctg tgagaagtga tattgaaact tctaaggtct
     1561 ttaatcccga gattttacct gatggcacga gttatgtctt tttaactaga gattttaagc
     1621 ttaaaaagtc taacatgcct gttaacttgc aagaagaatc cttactaaat taccaattca
     1681 agaatgctca cggtgagaaa tacggctatt ttcagtcttt tgaacgatca gatggcatag
     1741 tcattgtcaa ttatcaacta tcacctcggt accgtaatga gtggatgaac cagcattttc
     1801 ccaatgctga tcttatgatg attggttcaa tgtttgtatc tatcttaatc atatttatta
     1861 ttttaacttt ttattatgca aataaattga gtcagcaact taaacctata ttaagggtta
     1921 ctgaaaaaat ttcccaacaa gatttggatt ttcaaacttc tcagtctaca attaaggaat
     1981 ttaatcaggt tttaagtggt ttggatcata tgcgtatagc acttcgtgag tctttgatgg
     2041 aaaattggaa ggcagagcaa gataaacaaa atcagatttc tgccctaaca catgacttaa
     2101 agacgcccct aacagttgct cgtggaaatg cggaactctt agctatgacg tccttggatg
     2161 aaaatcaaac ggacttgtta gagcattttc aaaaaggtat tgcacaggtt gatgcttatg
     2221 taaaagagtt gtcagaattc aacaaaatga gtttgaagaa gaccctgacg cttgaagaag
     2281 ttccagttaa ggaatttgtt gaagacattt acgatcaaac cttgtcatta gctcaaacga
     2341 aacaaatcaa tgtggtattt gacaagaagg aaattgcgaa agaaagcata ggcaattggg
     2401 ataagtcctt gttgaatcga gctattatga atattgtttc aaatgccgta gagcatacac
     2461 ccagtggcag tcagttgctc ctgaccgcta gggtagaaga agatgaattc aagtttatat
     2521 gccttgattc tggtcctgga ttttcccttg aatctcttga aaacgctact cagctatttt
     2581 atcaagagga taaaagcaga catagtcgca atcatagtgg ccttggtctg actattgcca
     2641 atgatattat tcgtttacac tatggtagtc tttctcttgc aaatgacaat ggcacgggtg
     2701 gtgctaaagt gactatcatt ttaccccttt taaatacaga tgactcctag tcgccagatg
     2761 aggagttttt tgctatacta ctaagagtaa aaatgaagaa agatttgtgg gagcaggatt
     2821 tcatcttgtt tccgaagagg tattagtgtc atgtctcaat caaaagcaga ttatattaac
     2881 gtgattggag ctggtttggc cggatccgag gcggcttatc agattgccaa acgtggtatt
     2941 ccagtaaaac tttatgaaat gcgtggggtc aaagcaacac cacagcataa gacaacaaat
     3001 tttgcagaat tggtttgctc taactctttc cgtggagata gcttgaccaa tgctgtaggg
     3061 cttctaaaag aagaaatgcg tcgtttggac tctatcatta tgcgtaatgg agaagctcac
     3121 cgtgtgccag caggtggtgc catggcggtg gaccgtgagg gctatgcaga agcagtgaca
     3181 gctgaaattg aaagtcatcc cttaattgaa gttatccgta aagaaatcac agaaattcct
     3241 gatgatgcta ttacagttat tgcttcaggt cccctaactt ctgatgcttt agctgaaaag
     3301 attcatgagc ttaacggtgg agacgggttc tatttctatg atgccgctgc accaatcgtt
     3361 gataaagcaa ctatcgacat gaacaaggtt taccttaagt cacgctatga taagggtgaa
     3421 gcagcttatc taaactgtcc aatgaccaag gaagagttca tggccttcta tgaggccttg
     3481 actacagctg aagaagctcc tttgaattct tttgaaaaag aaaagtattt cgaagggtgt
     3541 atgcctatcg aggttatggc taaacgtggt attaaaacaa tgctctacgg tcctatgaaa
     3601 ccagttggtt tggagtatcc tgaagattat atgggtccac gtgatggtga cttcaagaca
     3661 ccttatgcgg ttgttcagct tcgtcaggac aatgcggctg gtagcctcta caatatcgtt
     3721 ggtttccaaa cccacctcaa atggggagag caaaaacgtg tcttccaaat gattccaggt
     3781 cttgaaaatg cagaatttgt tcgttatggg gtaatgcacc gtaactctta catggattcg
     3841 ccaaacttgc ttaaacagac cttccaatca aaatcaaacc ctaatctgtt ctttgctgga
     3901 caaatgactg gtgttgaagg ttatgttgaa tcagctgcct caggtttggt tgctggaatc
     3961 aatgcagccc gtctctttaa gggtgaagat gaagttattt tccctcatac aacagcaatc
     4021 ggtagccttc catattatgt gacacatgct gaaagcaaac attttcaacc aatgaatgtt
     4081 aactttggta ttatcaaaga attagaaggc ccacgtattc gtgacaagaa agagcgttat
     4141 gaaaaaatcg cagaaagagc tcttaaggat ttgcaaactt ttatagatgc ttgatgctaa
     4201 cataaaaagc cctcacaaga gtgaaggctt ttcgttttag agaggagcga atagaaatat
     4261 cgattagcca aagaatttct tagcgatttc ttgaccttgt ttgattttag cccattgttg
     4321 aggtgttgcc agctcattac ctgagtcaca tgaggcgaaa ccacattggt gaaaggggaa
     4381 gagacgtttt tttggaagga tttgactcgc tttttcaagc aaatcgagaa cacgttcttc
     4441 gtcatctagg tcagtcgttt aagaagacaa tagcccaaat acaacttcag ctttactgtc
     4501 tttaagggct tccagagctt tgatatcacc agctgtatcg ctatcccatt caaggaagaa
     4561 gcggtcatag tgttgctctg ccaagaattt cttagcgatg tcttcgtaag ttccttcaga
     4621 agcagaacgg atttcataat taccacgaca gttgtgtgtc caaaccgtta aaccaagttc
     4681 gtgagtatag tcaacaacct cattattgat agcaacaaat tcatcggcca attctgccaa
     4741 atcaccattg ccgtctgagt agaaacttgt agggtttgat gggtcaaaaa gttcccagag
     4801 gcagtcgtca aattgaacga ttttaccacc aacagccttg tattcatcca agaattcttt
     4861 ataggcatta atcaaacctt ttttgagttc ttcgtttgtt tcatagactt gtccaggaac
     4921 agccaatcga tcaaagatag caagttcagt gtaggcatga gcaggtcccc agatagtttg
     4981 tttggtatct tcatcaccag cttcagcctt aaccaatttg taaatatcta ggtagtggtg
     5041 gtttttacct gatagaggct cagtgatacg aataccgata tctttacgtg tttcatattg
     5101 accaccatca tggtctttaa aagtataacc atgctcagca atgtagcgtt caataccttt
     5161 gagtccccag acaaagtcca agtgccacat agaacgtcca aacttcccat cggtaaggat
     5221 gtcaattccg ttagcttttt ggtcagccac attcgcttaa tagatgcagt ttcagtttct
     5281 tgataaccag gaagggcatc atagaaagga tactggatgt cgtcacgatg ctcgatttcg
     5341 tccttgtatt tacggagatc cgcaggacga agaagagaac cgactaattg gaatttagat
     5401 tttgtcatta aatttacctc gaaatgtcta tttacatcta tattatttct tatgggaact
     5461 aatgaaaaat agttaatttc ttgctgtgta tatagtttta gactatacaa ggtttagctc
     5521 tgcaaaatga tacttcttat gataaaatgg aaagaaaacg atgaaggttg ggaatatgca
     5581 aaaaacattc tttattatta aaccagatgc tgttaaacgt catctaattg gtcaagtgct
     5641 tgatcgaatt gagcgacgtg gcttcgttat tgagcgtatg gagatgctga tgcttgacga
     5701 agaacgtctt aaagaacatt atgcccaatt ggctgataaa ccttttttcc ctagtatttc
     5761 tgaattcatg atgagtggtc cagcagttat tggtattatg tccggcccag gagttattaa
     5821 gtcatggcgt gatatgatgg gagcaactaa tcctggggat gctgctcctg gaacgattcg
     5881 tggagacttt gcaacagcac cagatggtga catgattcca aatatcgttc atggctctga
     5941 ttcagaagaa tctgcggctc gagaaattaa gatttggttt ggtgagtagg atggatatag
     6001 cacagattca atcagaatta gctcaggatg gactattaat tgatgtcagg actccagaag
     6061 agtacgcaga aggtcatgtt aaggatgctt tattaatacc tcacacgcag tttttcacag
     6121 ctgacattcc agctaaaaaa gacgcctcca tttacctcta ttgtaaaatg ggatctcgtg
     6181 ctgaatttgc tgcaggagta ctgaaagaac gaggatatac taaggttacc accttaggtg
     6241 gcctaggtga tatggaagca ctagggttta agtttgaaaa ataatacaca taaggtcact
     6301 agtggtgatc ttatttgctt tcaaaaagca tgacaaatta ttaacaacgc tttcataaag
     6361 tggtaagatt ctaaatgagt taagaaaaag cctatgaaaa tgactttgcc agaacttgat
     6421 taacttagca tattccaatt gagatagggc ttgtggttaa gcttgtgact acaattggta
     6481 gaggaggatt tcgtatgtca aaagttgcta ttgttacagg tgcaggtcaa ggtattggtt
     6541 ttgcgatttc aaaacgcttg gttgaagatg gtgttaaagt cggggtattg gactatgacg
     6601 ctgaaactgc tgaaaaagca gttgctgagt tgtcagaaga caaggcattt tccgttgtag
     6661 cagatgtgtc taaacaagct gaggtagcag cagctttcca aaaagtagtt gatcactttg
     6721 gcgacttgaa tgttgttgtt aataatgctg gtgtggcacc aacaaaatcc cttgacacta
     6781 ttactgaaga acagtttcaa cgtacattta acattaatat tggtggagtt atctgaggtg
     6841 cacaagctgc ccaagcacaa tttaaatcac ttggtcatgg tggtaaaatt atcaatgcaa
     6901 ctttacaagc aggtgtcgta gggaactcta acttaactgt atatggtgga actaaattcg
     6961 tagttcgtgg tattactcaa actttggcgc gtgacttagc tgattcaggt ataactgtaa
     7021 atgcttatgc accaggtatc gttaagactc caatgatgtt tgacattgcc cacgaagttg
     7081 gtaaaatgct ggtaaagatg atgagtgggg tatgcaaact tttgctaaag atattaccct
     7141 caaacgtttg tcagaacctg aagatgttgc agcagcagtt agcttcctag ctggacctga
     7201 ctcaaactac atcacaggtc aaacaatcat cgttgatggt ggtatgcaat tccattaagg
     7261 ttaaaaggga gagcgaatgg ctctcttttt ttgcttgata aaacataatg tttctgataa
     7321 tatagttata aataattatg tttttaaagg tggattccca tatcagacat cttacactat
     7381 attgctgagc acccattttt tagtcttatt ctattgggaa ttattgtact agcctttggt
     7441 ttagctccat tttcaagtag ttcaatagag aacaagcgtt cagctattat taataagcac
     7501 tacaatgata attttaagaa ataagaagga ctaaatgcag tcataaagca gatattagag
     7561 ataggcaaat gcctgtcttt tttgtataat aggaggtgac ggttcgtttt ttaacaatca
     7621 caagtaagaa ttaggaaaga ataaaatgcc aaatattgaa gaattaaaac aaagacagga
     7681 gaagattcgc aacttctcga ttattgctca tattgaccat ggtaaatcaa cgcttgctga
     7741 ccgtatcttg gaaaagactg agactgtatc aagtcgtgag atgcaggcac aactccttga
     7801 tagtatggat cttgagcgcg aacgtggtat cactatcaaa ctgaatgcca ttgagcttaa
     7861 ctacaaagct aaagacggcg agacttatat tttccacctt atcgacacac cgggacatgt
     7921 ggactttact tatgaggtgt cacgttccct tgccgcctgt gagggtgcta tcttggtggt
     7981 agatgcagct caagggattg aagcacaaac acttgccaat gtttacttgg cacttgataa
     8041 tgacttggaa atcttaccag ttatcaataa aatcgacctt ccagcggcag atcctgagcg
     8101 tgtacgtaca gagattgaag atgttatcgg attagatgcc tcggaagctg tgcttgcatc
     8161 agctaaggct ggcattggta tcgaagagat tctcgaacaa attgttgaga aagttcctgc
     8221 gccccaaggt gatgtggaag cacctctcca agcccttatc tttgactctg tttatgatgc
     8281 gtatcgtggc gtcatactcc aagtgcgtgt ggttaacgga atggttaaaa cgggcgataa
     8341 gattcaaatg atgtctaatg gcaagacctt tgacgttact gaggttggta ttttcactcc
     8401 taaagctgtt ggccgtgact accttgcgac tggagatgtt ggttatgtag cagcttcaat
     8461 taagacagtt gcggatactc gtgtcggtga tacagtgaca cttgcggata atccagccgc
     8521 agaaccactt catggttata agcaaatgaa cccaatggtc tttgctggtc tttatccaat
     8581 tgagtcaaat aaatataacg acttgcgtga ggctcttgaa aagctccaat tgaatgatgc
     8641 cagtcttcaa tttgagcctg aaacgtctca agcccttggt tttggtttcc gttgtggttt
     8701 cttgggcctt cttcacatgg atgttatcca agagcgtttg gaacgtgagt ttaacatcga
     8761 tctcatcatg actgcaccat cagtagttta ccatgttaac actactgacg gtgaaatgct
     8821 tgaagtgtcc aacccatctg aatttccaga tcctacacgt attgatgcca ttgaagagcc
     8881 ttatgtcaaa gctcaaatta tggttcctca agagtatgtt ggtgctgtta tggagttggc
     8941 gcaacgtaaa cgtggtgatt ttgaaaccat ggaatatatt gatgataatc gtgttaacgt
     9001 tatctatcaa attccacttg ctgaaatcgt ctttgacttc tttgataaat tgaagtcatc
     9061 aactcgtggt tatgcaagtt ttgactatga attgtcagag taccgtcgtt cacaattggt
     9121 gaaaatggat attctcctta atggtgataa ggtcgatgcc cttagcttta ttgtccatag
     9181 agaatttgcc tacgaacgtg gaaaacttat cgttgataaa cttaagaaaa ttattccacg
     9241 tcaacaattt gaagttccta tccaagcggc tattggtcaa aaaattgttg cccgtacaga
     9301 tatcaaagct cttcgtaaaa acgtcttggc taaatgttac ggtggtgacg tttcacgtaa
     9361 acgtaaactc ctcgaaaaac aaaaagctgg taagaaacgt atgaaagcca ttggttcggt
     9421 ggaggtacca caagaagcct tcttgtctgt gctttcaatg gacgaagatg agaaataaga
     9481 atgatagtag aatgtgatgt tctggctatt ttagtaaaaa gttatgataa agaggatttt
     9541 aaaatttacc ttctcaaagt gacgtataga gaatggcacc actaatccaa catataaaac
     9601 attggaagaa attgccgctg caaccaatac tagattagtt gttgactttg ttccaataaa
     9661 gaactagttt ttgtatacac tcaaaaagct ctataatctc tatagtggtt ttacctacta
     9721 cagaaatcat agagtctttt ttatattata cccttattag aggacaacat cataccttaa
     9781 ctacaccaca aaagttagac atcgaaagtc taacttttgt ggtgtcttta ttttctattt
     9841 gtttagccaa cagcaattac aataatgctt tcaaaaatta gaagtaagat agctaaaaaa
     9901 ctttctttat tcatagaaat taacctccta tctcactata tgatataata cttttaagtt
     9961 tatctgggaa attctcgtat atgcaaaaga ggtgcttttt atgaaagatt atggaaaatt
    10021 atttaagaaa tttagagagt ctaggggatt agtcttaaaa gatatcgcaa agttaggcgt
    10081 atcagtatct catatttccc gctttgaacg tgaaaataca gatttgacaa ttagtaagtt
    10141 tatgtcagct ttaaatgcga taaatatgcc tattgatgag tttatgtatg cagcaaacga
    10201 ctttcagaga gatgagttta atgaaatctt agaaaagatt agtttatttg tttcagcaag
    10261 gaacgtgtca ggtatggaaa agttattaat ctctcaagta gaaaaaatcg aaaagcgtga
    10321 gactttttat actctaaata ctattttaat aaaaattcgt ttacaggact tatcagacaa
    10381 aagttactat gatgaatctg atatccaata tttatcagac tacctattct ctgtagaata
    10441 ttggggttgt tacgaactac tgttatttgc gaatactgta gatgtatgaa tcatcaaaca
    10501 atgatgcttt tatcaagaga aatgtgtaaa cgttcagaat tttacaagga tttaccaaac
    10561 taccgaaggt tacactcaac aatgctatta aattgttata tcataagtat tgaaagagat
    10621 gagtatattg atgcgttgta ttttgaaaaa cagttaaatc atagttgttt tacggaaact
    10681 gagatttacg agaaattagt gtttcattat tcaaaaaatt tatatgaatt aaagaagaat
    10741 aggagcaata aagctattct agaaatgaag aagtgtatta ctgcaatgaa gctggctaat
    10801 agtgagaatt tagctataaa atttgaaaat catttatctg gagtgttaaa aatgtagttg
    10861 gatttgtgta tatggtataa attatcagtg tcaaaattaa atgatatatt attgatatga
    10921 gaattattaa atttcctgaa cagatttcag aagatatcat tcattatacg tttctagatg
    10981 atattatctc ttataattgt gaaaagtgta gaggatcttg ttgtcatgtg aataattctt
    11041 tattacttga tgcaaagaca gcaagttttc taaaacgcac gtatcttaaa gattttattg
    11101 ttagtgatga tagtgtttca ttgttgagtt gtggtaaaaa gtgctggttt cattctgaat
    11161 tgggttgtac gataaatgat ttaggcttga acaagccatt aacttgtgaa ttatatcctt
    11221 ttcatattaa gaaaattcag aacttctata ttgtttcttt tactccttgt ccgacatttc
    11281 aactgaacct tggtgagggg cagaggtaca aggatataga ggatgtagtt ttacgatata
    11341 ttaaaactgg ggtgccagtt tttagtccgt ctttgcatgt ttcagaggaa aggctgaaat
    11401 atgagattga gtatcaaaac aattttaaaa acactttatc agagtattat cgaacaaaga
    11461 ctgccgatgg cactacagag tttaaagaat atgaaaaatg gtatatatat tatttagatt
    11521 ttagatgggg aagtataccc ttatcttata caagttcaca agcaaatcaa ttttggaatc
    11581 tttacaagag agtttgtgaa gatgtttata aaaaaatatc atatatacga acagataaca
    11641 tatactttat tattgcaaat cagtttaata agacaatttc aaagcatttt cagctaaatt
    11701 ttatagataa agaatgattt ctatgatttg ttatgggtac ttattgattc ttaaataaat
    11761 aatggaggat attacgatgc aagttagtga tgctattgca caaattgaat tagcagaaga
    11821 agaagttgtt tctagcggtc tatctattga cattatggaa attaaacctt ctgttgctac
    11881 agagttgatt gatggactca aaggtcgttg cccaccgtct gtctaataga actgattgta
    11941 ggattagagt ctatttctaa tcctttggtt tttatattaa tatttttgga agattgcagg
    12001 gaattaatat gacgagcaat gtttactcga tttttttaat tggtacaata agcaaggaat
    12061 actcaggaat aataggaata ataaactatt ttcattaaat ttagctacat ttttagcttt
    12121 aaaatttatg taccaatttt cattgaaaaa gttttctgat tcaaagagtc aggtaataaa
    12181 aaatgttata gattttctaa ataacaatga aatatcactc tctaagacca acactaaaat
    12241 tgttgaattt tcaacgaaaa taccattaaa agtgatacag attgaggtca cgaacaaatg
    12301 taacctaaga tgtatgcatt gttatttacc tgattattca aaggagctcg atagaaagaa
    12361 aatttcaagt atagtatatg aagctaagca gctaggagta atggatgttg atttcactgg
    12421 aggcgaacca ttattattac agggattaag tgaaattatc gaggaagtat taaaagaggg
    12481 aatgtgtaca acaattttta caaatgctgt atatattcct gaagatttta aaatattgat
    12541 tcaaagatat gatggtataa gactaaaagt tagtttagat ggttggaatg aaacaataca
    12601 tgattcaatt agaggaagag gtacatttaa gagaacaatt aagaatattg aatattttag
    12661 gagtttagga gtacctgtta ctgttaatgt tgttttgaat aacaagaata ttagtggagt
    12721 gaagtatttt ttggagttgt ttgatcgatt agatgtgaaa tatgcttttg ataggttttt
    12781 accttttgaa aggaataatc gactatcaat tagtgatgaa gaattcaata atgctatttt
    12841 gtgtattccc aatattcaag caaattgtaa taatatatcc gaatccacat ttgaatcatt
    12901 ttattgtggt gctggcaatt cttatgtgtt tataaattcg tcaggtgatg ttggattttg
    12961 tccgacatta tcctccacta aattttgtgg aggtaacatt aatgaaaaga ctttaaatga
    13021 tatttggatt aattcgaagt tcttcaatca tattcgaaat gtacgatgta agtattataa
    13081 tgaatgccct gcaaattatg tttgtcaagg tgggtgtaga agtcgagctc agtttttcgg
    13141 aggttctatt gggagtcccg atatacagga gtgcaagtta gcatataatt taactgggat
    13201 taagccaaag tcaatgagtt tatgaaaata ttatctatta tttatgatgg tggaagtaga
    13261 attccaggag cgagatttgc tcccacaaaa tattatcaag aagcgatgtt atatgatagg
    13321 aaagattctg atataattac aattaattta ggtaatcaag atttattttc tattgattta
    13381 gaaagtctaa gtcgaactat tgctgaatct aaagttcaga ttgctttagg aggagatcat
    13441 tcagttactt atctattagc aaaggccact gttcgagagg gagcatattt aattgtttta
    13501 gatgctcatt tagattactt caaagacttt gaaagtgttg taaaaaattg gaatttttta
    13561 agttttttaa ccgatatttt tgaaaaaata attatcattg gggaaaggaa ttttgagttt
    13621 cctagttcat ttgataataa aataatcatc ctctcaatgg aggagtattg gttaaataag
    13681 agtagagttt tgaaaaagtt agatagttat attgatgagt caaaagatat ttacttatca
    13741 atagacattg atgttttgga tccatctgtt tttgattcag tatcatatcc tattattgga
    13801 ggatttcaaa tgaacgattt tcttggaata atttccaaaa ttttatgttc tgataaggta
    13861 tatttttgtg atatagttga gtacaatccg atggttggaa gtgataatgc tcacattttt
    13921 taccaaatga ttcaatttgt taaatcaaaa ttaaggagga tataggaaat attgaaaata
    13981 aaaaaatatg cagcattgag tatttatttt aatcgtttct catcgttaat ctcagagtat
    14041 ggttatacta tcttgatcaa cattctattg tctagaattt ctgtgcaatt agttatgtat
    14101 ttttgggtgg taaagtgttt agctgcaata gttacaaata ggattaatat ctcaaatagt
    14161 aaactgagca gaaaatacct gcttattctg ttagaaatta caaaggcaat cttacttttc
    14221 ttactaggtt ttggattaaa ccatataatt gtcctattag ttgtattcat aattgaggtt
    14281 gtcaatgtat tgttttccag tttattatat agttgtgtac caattattat agacaaggat
    14341 tcattgatta agtttaacgc taggtataca agcattggtt cagtatctta ttttttagca
    14401 ccgttgtttg ttggtttatt tattaataaa agtcactttt tattgtttgc agtttatgct
    14461 cttcttttga tagtgggagc tactagtctt ttatttttac caaatatttc gactttaaat
    14521 ttgaaagaag aaagaaaaaa acaaaattta aacattacat tatttaacat tctgagatcc
    14581 aaaaaaattg cattagttct attatctgga gttattgtgg gatcaattgg agttgtttat
    14641 gatacttatg aagttgttta tttaacaaag tatctcggta ttagtgattc tatgtattcc
    14701 ttttccttat catttttagc agtttcattc ttagtaatga gcttccttct tagcttcgtg
    14761 aaacaaataa gttctcatat gaaagctttc gccttaggtc tttcatttta tgttctatat
    14821 ctacttttat ttagtacatc ttcgaacatt tatacagtac taatgagtta tgtttttcta
    14881 gcgataggtc agacaatgat ggggataatc gaaaccaatt attttcagtt gtcacttaac
    14941 atgaaagaat tacagaaact atatatttac tcggagacct tacattctgt attttcaggc
    15001 attgctgttt tagtaatagg aagttttgcc tttttaagta gtcatcttgt tttagttttc
    15061 agaagtcttg ctgtttttgc tctgtttatt cttctgtgtt attgtgtgtt tgtaaacctc
    15121 aaaaaactaa gcattgataa gtaatattta taaatcagaa aacaagcaaa tgagatagtt
    15181 aatttataaa gtagacaaac gctattttga gtgtttgtct ttttttagtc acctagtctg
    15241 ccttttttca caagattgtc tgaaaactgt gctataatga taacagaatt gtgaattgat
    15301 gaaagtttgt gaaaaaacga gcagactttg acactttgtg acttatactt gaaaggaaag
    15361 ttggctctac cattttaggg ctagaaggac tgtgttcatg tcagaagaaa agcaattgta
    15421 tggtgcagat ttagtggttg atagtttgat caaccatgat gttgagtatg tctttgggat
    15481 tccaggcgca aaaatcgata gggtttttga taccttggaa gataagggac ctgaattgat
    15541 tgttgcccgt catgagcaaa atgctgcttt tatggctcaa ggtgttggac gtattactgg
    15601 gaaaccaggt gtagtattgg taacatctgg tccaggtgtc tccaatttgg ctactggttt
    15661 ggtaacagcg acggatgaag gagaccctgt tcttgctatt ggtggtcagg ttaagcgtgc
    15721 agatctcttg aaacgtgccc accaatcaat gaataacgtt gctatgcttg agccaattac
    15781 caaatatgct gctgaagtac atgatgctaa caccctttct gaaacggttg ctaatgccta
    15841 tcgtcacgct aagtcaggga aaccaggtgc aagcttcatt tcaattcctc aagacgtgac
    15901 ggatgctccg gtcagtgtta aggctattaa gcctatgaca gatccaaaac ttggttcagc
    15961 atctgtttct gatattaact atctcgcaca agccattaaa aatgcagtgt tgccagtctt
    16021 tcttttgggg aatggtgcct catcagaagc cgtaacttac tctattcgcc aaattttgaa
    16081 gcatgttaaa ttgccagttg ttgaaacttt ccaaggtgcc ggtatcgtgt cacgtgacct
    16141 tgaagaagat actttctttg gtcgtgtagg tcttttccgt aaccaacccg gagacatgtt
    16201 gcttaaaaaa tccgacttag ttattgccat tggttatgac ccaatcgaat atgaagcacg
    16261 taactggaat gctgaaattt cagcacgtat catcgttatt gatgttgagc cggccgaggt
    16321 ggacacttac ttccaaccgg aacgtgaatt gattggtaat gtagaagcga gcttaaactt
    16381 gcttttgccc gctattcaag gttataaatt gcctgaaggt tcggttgaat atcttaaagg
    16441 tttgaaaaac aatgttgttg aggatgttaa gtttgaccgt cagcctgatg aaggtacggt
    16501 gcatccgcta gatttaatcg aagttttgca agaacaaaca gatgatgata tgactgttac
    16561 ggttgatgtt ggtagtcact atatttggat ggcacgttat ttcaaatcgt atgaaccacg
    16621 tcatttgctt ttctcaaatg ggatgcaaac gctaggtgtt gctcttccat gggctatctc
    16681 tgcagctttg gttcgtccta agacaaaagt gatttctgtt tctggtgatg gtggtttcct
    16741 cttctcagca caagaattgg aaacagcagt tcgtttgaaa ttgccaattg tccatattat
    16801 ctggaacgat ggtcattaca atatggtgga attccaggaa gaaatgaagt acggtcgttc
    16861 atctggggtt gactttggtc ctgtagattt tgtaaaatat gctgagagct ttggagccaa
    16921 aggttatcgt gcaacaagta aagcagcatt tgctagcttg cttcaagagg ctttgactca
    16981 ggctgtagat ggaccagtcc ttattgatgt tccaattgac tataaagata acattaaact
    17041 cggcgaaact attttgccag atgaatttta ctaaaaagag ggtgtagaca tgtctgaagc
    17101 cataaaatta tttcaatata atactttggg agccttgatg gctgggcttt atggaggtac
    17161 tttaaccgtt ggagagttgt tagagcatgg agacttgggt ctcggaacat tagattctat
    17221 cgatggtgag ttgattgttc ttgacggtaa agcctaccaa gctaaaggct ctgaaggtaa
    17281 agtcgaagtg gtagaagttt ctcctgatga aaaagttccc tatgcagcag tcgtacctca
    17341 ccaagctgaa gttatcttcc gtcaacgtta tgaaatgact gataaagaac ttgaggatcg
    17401 tattgaatca tactatgatg gggtcaatct tttccgttca atcaaaatca aaggtcattt
    17461 taaacacatg cacgtgcgca tgattccaaa atcaaatgcg gacattaagt ttgctgatgt
    17521 tgccactcgc caacctgagt atgaggtaga tgatatttca ggtacaatcg ttggtatctg
    17581 gacacctgaa atgttccacg gtgtgagtgt tgctggttac catctccatt ttatttcaga
    17641 tgacttgaca ttcggtggtc acgttatgga ctttgttatc gagaatggta ttattgaagt
    17701 tggaccagtt gaccaactcg atcaacgctt cccagttcaa gaccgtcaat atctctttgc
    17761 taaattcaat gttgatgaaa tgcgtaaaga tattactaag gctgaataag catataaata
    17821 agatactgtc tctttgtcaa ctatagtggg tgacgaaaag ctaatatcta gagagggccg
    17881 gataggtcct ctttttatga atgttcagag tgatgaagac acgcttctta aagttgataa
    17941 agtttctaaa accgaagccc aaacgtttga tgtctttgat caacttatta gtcgcttcaa
    18001 gtttcgcgtt tgaatagtcc gtttctagtg cgtttttgat gtattgcttg tgtctaagaa
    18061 aagtcctaaa gacagtttga aaataatgat tgaccttgct cctattttcc tctatcagtt
    18121 caaagaactc atctactctc ttctcctgaa agtgaaaaag caaaagctga taaagtgtat
    18181 agtagtcagt aagctctttt gaaaagacta gtgtcttcgc aacaacttca tgtggtgcta
    18241 aagtttggcg gaaagtcttt gaataaaaag agttgagaga tagtttacgg ctgtcctttt
    18301 ggaagagtcg ccagtgattt ttcagggctc gatagggtag tgacttctta tcaaactggt
    18361 tcataatggc aattcttgtc tttaaaaagg cacgtccaag gtgctggatg atgtggaaac
    18421 gatcaagaac gatttttgcg tttggaaaga gcttgcgagc cagtggagta taagctccag
    18481 acatatccat cgtgataaac tttacctgtt atcggacttt caatggatac ttcaaaagta
    18541 gtttcgtata gtagtttggc ggcgattatc aaggatggct atgagttgga ttgtctcata
    18601 gttctgcgcc acaaaagcca attcctcttt cttgaaccca aactcatccc aggacataac
    18661 agcagggagt ttgtcataat gttccttgaa agtaaactga tcaagcttac gatagacagt
    18721 ggacgtcgac acgcgaagtc ttcttgcaat atcagttagt gacaccttct cagttaggag
    18781 ttgtgtaact ttttgtcgga ctagattgga gatttagcag tttttctcaa cgatagatgt
    18841 ctcagctacc gtgacacttc tacaactttt acactggaaa cgacgttttt tcagacgtag
    18901 tagagttggc gttcccgctt gctcgagaag agggatttta gaaggctttt gaaagtcgta
    18961 cttgatcatc tttccttggc agtgaggaca tgatggtgca gggtaatcaa gttttgcttg
    19021 aatctcgata tgagtgtcag tttcaaaaat aagtgaaatc ttgatatttt ggtctttaat
    19081 tccgattaat tatgtggtat tcttaataag tctcataagt tcttcctaat gatggtttgg
    19141 ttgcttttca ttatagttct tatgggactt tttgtgtaca ctcaaaaagc tctataatcc
    19201 ctacagtagt tttacccact acagaaatta tagagccaag atactcccct attcgacata
    19261 ggggagtatc ttgttttaaa acgacgaagt ggtcctaact cttccgtttt atttattaag
    19321 ttatagcata tctcactcaa cagattttag agcctcgagc atattgactt tcttaaggtg
    19381 ttggttcaca aagataccca gaacctgtca gaatgataat gattactagt gttggaacag
    19441 cgtagatgag ccagccaaga tttggattga acataatatt ttcaggtggg ataacatcta
    19501 ccatgtattg atgcagtccc aaaccaagtc cgaattcaac caagatacca atgatagaaa
    19561 gacaaattgt ttctcgatag atgtagagcg tcacttcttt attaaagaaa cctagaacct
    19621 taatggttga taattcgcgg atacgctctg ccacattgat attcgttaaa ttgaagagaa
    19681 caacaaaagc aagaagaata gaaacactaa tcaaaactcc cataacacgg ctaagtgagt
    19741 tgacgatggt cttgatttgt gcctttagag tagtattttg gacatcccct tttacaccat
    19801 caagagacat aaatcgactg gctgtttgct caacattttt gtctgaatga tctttcagtg
    19861 taagtatcgt agcattttgg ctagcctctt ttccgaaagc atccttataa gtagattcgt
    19921 tcataaagat gaagtacccc atgtacatct cagaaatacc agcaactttg agtttgatgt
    19981 ctttgtcctg gctattttga acggttactt catcacctac agaaatacca gctaggtccg
    20041 ccaatttctc tgagataata atgccttttt cagtcaaatc aagcttctga ccagtttcac
    20101 gatgattgag tttgatgtaa ttttgaagtg ttttttgatc tttatcattg acaacaagtg
    20161 ttgtgatatc ttgacgatcg ttattacttc ctacatctaa caggtgctac ggacggtatc
    20221 ggtaagcatc tagcaaagaa accgtctagt gaaggctatc atatcatcct ccacggtcgc
    20281 aatcctcaaa agctggaatt ggctactcag gaggttcggg cagtctcctt gagaggcaga
    20341 gtgtctagct acttggctga tttttcaaaa ttagataatg tttatcgatt tgtggaggaa
    20401 atcaagcgag actttcaaag gattgatatc ttatttaaca atgcaggtct gtatgcaggg
    20461 aaagagcgaa aagcgagtgg tgaaaatgtc gaactaactt tcatgttatc cgttctggtt
    20521 ccctatattt ttataacaga gctaatcccc ttgttagaaa aattgcctga tggccttgtt
    20581 atcaatacct cttcctatat gcaccatttt gcgaaagtga aggatttgga ctttggcttt
    20641 gagaaagaat acaatcccgg tttggcctac aataattcca agctctacac catttggatg
    20701 acacgctatc tagcaagaga tttcttttta aaaggttcaa ataccactat taatgcctac
    20761 catctcggct tgattttaac caacttaggg aataattcta gtgataaaaa gacggaaaag
    20821 tctctcttcg gacgcttgat gaagtctctt tcaaaagatc tagatcaggg aatcgaaaca
    20881 ggctattatc tcaccttatc agaggaagtc agtggcttga ctggctacta ctttgatgaa
    20941 aagaaagtca agtcggtatc tgaaaaaggc tactcatttg aaaaaacaca gaaattaatg
    21001 aattactgcc aagaaaaggt caaaatgttt aaagaaaagc agaatgttta atatcataaa
    21061 tataagaaaa aagctcaagt tttcattaat aaaacttgat cttttcttat acaagagtta
    21121 ataaaatcgt aattaccaga gcgattccga tccgaatcag gtagtgggct actagatgga
    21181 aatttccttt atgcttgcca ttccaatagg ctccgtagca aatcaagcta actccgatca
    21241 gccaaaggaa taaagcaaca atcggcaaaa ggaagtaaag gatgagagaa ggtcgcaagg
    21301 ttgcttccga taaggagaag ccgatttcct agagtattct tgtgctttct taattctgaa
    21361 agactggcca ttaaatgaag aagagcaaaa gcaagggata agaaagctgt gaaaatacca
    21421 agaagaatga gaaggagcat agttttcctt tctatgatac atgatgtaaa gtcgcacctt
    21481 agttagaagc gacgtttaaa atctccaaat aaaactggac tacttcctgc tcgctgtagg
    21541 acttgccttt tttcaaccac caggtcaggg tttcaatgaa gttggttata accaggtgct
    21601 tgagatatga gtgaggaatg ttggggtgtg attgaatcag ttcatcagct accattggat
    21661 agacgtcatg ttccagttct tttcgcagct gccggataaa ataatcgttt tttgaaagca
    21721 agagactggt tacatggtct tgatttttct tgaaatgttg aaagatatgg gccaggtagt
    21781 cttgtggaga gaggtattga gtacgctcaa acaaatggtg aaagagcttt tggcagagct
    21841 catccagtag taactctttg ctctcataat ggctgtaaaa ggtcgaacgc cccacatcag
    21901 ccaagtcaat aatctcctga acggtgatgg cctcataatc tttttggtta agtaagtaca
    21961 agaaagcttg atagatggct tttctagtct tggtaatgcg acgatcttgt gcagtcatat
    22021 ggacactatg aacaaactgt tcagtaacgt acacagcgaa cggtttgccc ctatcctttc
    22081 tgttggtagt attggataat agatattgaa tatgatgttc gtgaatctat tataccaaag
    22141 gaaggtaaaa aatgagttca aaatatgcag tctggttggc ttttttcttg aatctaagct
    22201 tttccattgt tgagtttatt gcagggggaa tctttgtttc cagtgctgtt ctcgctgact
    22261 ctgtccatga cttgggggat gctctagcca ttggcctctc ggcctttcta gaaacaatct
    22321 ccaatcgtga agaagatagt cgctataccc taggctacaa gcgttttagc ttattagggg
    22381 ctttggtaac ggcagtcatt ctgatgacag ggtctggtat ggtgatttta gaaaatataa
    22441 gcaagctttt ccacccacaa cccgtcaatg acgaagggct tctttggttg ggaattattg
    22501 ctatcagtgt caatctgctg gctagtctgg tcattcgtaa gggtcagacc aagaatgagt
    22561 ctattctcag cctgcatttt ttggaagata ccttaggttg gttggctgtc atcctgatgg
    22621 ccattgtcct ccgatttacg gactggtata tcctagatcc cctcttgtct cttgctattt
    22681 ccttctttat tctgtccaaa gccattccac gtttttggag cacgctcaag attttcctgg
    22741 atgctgtgcc agaaggggta gatatcaagc aagttaagaa tgacttagag cagttggata
    22801 atgttgctag tatcaatcag cttaatcttt ggaccatgga cggcttggag aaaaatgcta
    22861 ttgtccatgt ttgtctggag catgtcaaac atatcgaggt ctgtaaagag tctatccgag
    22921 acttgctcaa agagagtggc tttcaaaatg tcaccatcga agttgatgaa gacttggcaa
    22981 cccaccaagc tcacaagcga aatatcgaag agctagaagc agaaagtgag cagcaacacc
    23041 atcattaagg tttgttttta aactcttaga gtctaccttt aagagttatt ttgataccaa
    23101 gttccctaaa gtgatccttt tcatgataaa atagaacaaa tgtagaacaa ggattaatta
    23161 tgagtaagag agctgtgttg atgatgacct ttgggtcacc agaagagatt acctatgaag
    23221 gagta
//
