GCA_000273155.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaADDNNMEL_1 (original name was: gnl|Prokka|ADDNNMEL_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	RRE-containing	1,374,419	1,394,772	polysaccharide C	Saccharide	20%

gnlProkkaADDNNMEL_3 (original name was: gnl|Prokka|ADDNNMEL_3)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	NRPS-like	68,247	110,676

No secondary metabolite regions were found in these records:: gnlProkkaADDNNMEL_2 (original name was: gnl|Prokka|ADDNNMEL_2); gnlProkkaADDNNMEL_4 (original name was: gnl|Prokka|ADDNNMEL_4); gnlProkkaADDNNMEL_5 (original name was: gnl|Prokka|ADDNNMEL_5); gnlProkkaADDNNMEL_6 (original name was: gnl|Prokka|ADDNNMEL_6); gnlProkkaADDNNMEL_7 (original name was: gnl|Prokka|ADDNNMEL_7); gnlProkkaADDNNMEL_8 (original name was: gnl|Prokka|ADDNNMEL_8); gnlProkkaADDNNMEL_9 (original name was: gnl|Prokka|ADDNNMEL_9); gnlProkkaADDNNMEL_10 (original name was: gnl|Prokka|ADDNNMEL_10); gnlProkkaADDNNMEL_11 (original name was: gnl|Prokka|ADDNNMEL_11)

Compact view

gnlProkkaADDNNMEL_1 - Region 1 - RRE-containing

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Location: 1,374,419 - 1,394,772 nt. (total: 20,354 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaADDNNMEL_3 - Region 1 - NRPS-like

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Location: 68,247 - 110,676 nt. (total: 42,430 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 68246 - 110676:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg3_85

AMP-binding (12..401): X

nrpys: Ile, Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFLGVVLK
Nearest Stachelhaus code(s):: Leu or Ile DAIYLGVVLK (59% 8Å match); aIle DALVFGVVLK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)