LOCUS       c00003_gnlPro..        24639 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ADDNNMEL_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 20:35:20
            Original ID  :: gnl|Prokka|ADDNNMEL_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 426132
            Orig. end    :: 450771
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24639
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[436132:440771]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             239..1753
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 268.7; E-value:
                     2.3e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_352"
                     /sec_met_domain="AMP-binding (E-value: 2e-81, bitscore:
                     268.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDEKIGIVAENRIETYAAILAVLAGGKTYVILHPAYPEERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKTLSEQQSHSSDEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSSLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYQLTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQTELLERFR
                     KSAPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSALVLIHRPDGQIYYRTGDLCILDGDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
     CDS             1768..2010
                     /locus_tag="ctg3_353"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRNILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFNFREVIKFKNVGDLCSALLTKME"
     CDS             2014..3396
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_354"
                     /sec_met_domain="MBOAT (E-value: 4.6e-21, bitscore: 70.5,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFSFLALFTLCFFLYYAVKGRARNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRRWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRNNLPQYI
                     GKYAADSLLIVRTYLLFALSLIFFRVQSLSDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             3415..4455
                     /locus_tag="ctg3_355"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRDSIAYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNVLIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFIIGPDYY
                     QKKTSREDIKILKAILGDSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             4560..4952
                     /locus_tag="ctg3_356"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKREDKQLVAKKEGYQTTPFVLESTFNNACLWNILFWPGFLVD
                     LGTQKMNKWDNTIINIEMEKENTENK"
     CDS             complement(5145..5774)
                     /locus_tag="ctg3_357"
                     /transl_table=11
                     /translation="MLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGVD
                     YVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALG
                     KPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDH
                     YQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(5758..6279)
                     /locus_tag="ctg3_358"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALAFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKYGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(6300..7091)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_359"
                     /sec_met_domain="F420_oxidored (E-value: 8.2e-13, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVSHYGVFYPMQTFSKQREVDFKEIPFFIEASSAEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(7088..7420)
                     /locus_tag="ctg3_360"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(7423..7920)
                     /locus_tag="ctg3_361"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(8126..8668)
                     /locus_tag="ctg3_362"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             8786..9769
                     /locus_tag="ctg3_363"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLIAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALQDAHQNGFRHMEF
                     MDAGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_364"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.1e-22, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10531..12084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_365"
                     /sec_met_domain="CT_Btheta (E-value: 1e-289, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12105..13019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_366"
                     /sec_met_domain="OAD_gamma (E-value: 6.5e-15, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             13045..13476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_367"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4e-21, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKTVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             13479..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_368"
                     /sec_met_domain="OAD_beta (E-value: 2e-152, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14788..16119
                     /locus_tag="ctg3_369"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             16134..17426
                     /locus_tag="ctg3_370"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVVLQAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIKKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIGDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             17842..19692
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_371"
                     /sec_met_domain="Alpha-amylase (E-value: 2.8e-62, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVC
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWADDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             19850..20290
                     /locus_tag="ctg3_372"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGAEMEASRITECIEDLKRLHEVLNEI"
     CDS             20303..21370
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_373"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1.1e-10,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLARLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMAKLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             21375..22970
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_374"
                     /sec_met_domain="MFS_1 (E-value: 3.4e-13, bitscore: 44.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAQTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYAFVIPLLIALFIHRQRTQGKPFVSLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFSEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(23065..24069)
                     /locus_tag="ctg3_375"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 agtatcaata aagtatcgtg ttgtctatcc cattcaaagt cgtcggctat gaagccaacg
       61 ctatttcccc ttccgaaaga gggaaagcga gaccgggcac gtgcgtacca cacaattaac
      121 attctttaat cgattgtgcg tagggagatc agaccatttc actgtcatct taataaacga
      181 tctcaagaag atatataaag aacccctaaa cccaaaacat gaataaaaac taatggatat
      241 gacaacatct tcccagaagg atattatcaa tgatattctt tccgccatgc aatgttatcc
      301 cgaaaacgaa gcattcatta ttgacgataa acattatact tatgcccaac tcggtgaaat
      361 aacagcttct atcacccatt cgctatcaga aataaaagat gaaaaaatcg gaatcgtagc
      421 ggaaaaccgg attgaaacct atgctgctat tctggcagta ctagccggcg gaaagaccta
      481 tgttatcctg catcctgcct acccggaaga gcgtaatctc aaaatagccg ctctggccgg
      541 actgcgtact ttgctctgta caagtgacac tgaccggtca gcattcggca ccggacactt
      601 cagaatcatc gatacggacc ggctaccggg aaaaacactg tcagaacagc agtcccattc
      661 atcggacgaa gaaaggaacg cttatatcat ttttacatcg ggaagcacag gcgagcccaa
      721 aggagtgccc atcacacggg ctaacttgaa cgccttttac cgggcataca gttcgctcga
      781 ctggaatctg gatgaacatg atcgcatgtt gcaaatgttc gaacttacat tcgatgtatc
      841 cgtagtatct ttactgtatc ctcttacttt aggtgctgcc gtttatacgg taggccatca
      901 ggatgtaaag cacttcaagg tgtttgaact tctggagaag tatcaactga cctttgccac
      961 tgtcactccc tcactgctac aactcctttc accctacttc gacgaaatca atctgccctc
     1021 tctgaaatat ctgggagtat cggcagaagc atcgcaaacc gagctgttgg agcgattcag
     1081 aaaatcggca cccaacgcaa cgttcatcaa cctatacgga ccgaccgaag ctacgattta
     1141 ctgcacctgt taccgtattc cagcttcgga caaatgcaag cattacaacg gaatggtggc
     1201 tatcggaaaa ccatttcccg gcatccgcgc catcattgcc gacgaagaag gaaacgagct
     1261 acctcaagga gagacgggag aactttgggt atccggccgg caggtaatga aaggttatct
     1321 ggacgacccg gaaaaatcgg cattggttct gatacaccgt cccgacggac aaatctatta
     1381 ccggaccgga gacttgtgta ttctggatgg cgacggggat attatttatt gcggacgtaa
     1441 agactatcag gtaaaaatac agggtttcag gatagaactg agtgaaatag aatatactgc
     1501 ccagtcgttt ttcaagactc cctgcagcgt ggctgccgtt ccgttgctct gcgacggaat
     1561 ctgtaacgaa ttgcacctgg ccgtcgagac aactgaatgt actcaaagcg cattgataga
     1621 atatctgaaa gaaaaactgc ccaaatacat gctgccgaag cagattcatt gtatttccca
     1681 atttccggtg accaatagta ataaaacaga ccgtaaaaag attgccgaac tgataaaaga
     1741 gaagaaactc taaaaacaat aataaatatg aatcgagaag aagtattaaa acaactacaa
     1801 agcattttcc gtaatatctt aaaaaaggac aacgtatgta tcgacgaatc atctacctca
     1861 aaagatgtag atggctggga ctcgctaacc cacatgcaaa ttatagctca aatcgagaaa
     1921 catttcggag tacgtttcaa tttcagggag gtcattaagt tcaagaatgt cggcgatttg
     1981 tgcagtgcct tattaaccaa aatggaataa acgatgcagt tcctctcttt tagtttcctg
     2041 gccctgttta ccctctgttt cttcctctac tatgcagtca aaggccgtgc ccgcaacctc
     2101 atactactgg taaccagttg tattttcatc ggatggtact atctgccttt cctgttgacg
     2161 gcagtagtgg tagcactatt caccttcttt tgggcacaat ggatggaaag cagggcaaaa
     2221 gccggaaaaa agaccaaacc cgtctatatc gcaggaatca tcgccctgat cggcggatgg
     2281 ctccttcttc atggcacggt catagatgat atcatctttc cacttgggat gtcattttac
     2341 acatttcaag ccatcagtta tctgacagac gtgtactggc aagagcaacg cagcgaaaga
     2401 aactgggtgg atttcctgat ctatatgctt ttcttcatga agtttctctc cggccctatc
     2461 gaacggggtg gagacctgtt gccacaattg aaagatcccc gcccgttcat ctactcaaac
     2521 gcggtgaccg gactgaaata tattttactc ggactgatca agaaactgct gatagccaat
     2581 cagatctccc cacaaacaga tgtcatgttt cattcgattc atgacctctc gggtgtacaa
     2641 ctgctaatga cttgcctact ctaccctatc gaactgtatg ccgatttttc gggttatacg
     2701 gatattgcta tcggaggggc ctatatgttc ggcatcaagt tgtctcctaa cttcaaccgc
     2761 ccgtttgcag cacgctcgac tgccgacttc tggcgccgtt ggcacatgtc actctccttc
     2821 tgggtacgcg attatctcta tgtaccgcta accgccggta cccgtaactg gggacagtgg
     2881 ggaatctact tcagcctcct catcaccttt ctcgcattgg gtttgtggca tggggccgga
     2941 ttgactttcg ccatatacgg cctgattcag ggtgtcctta tctgctggga aatgaaaaca
     3001 gctgctttcc gcaataatct gccccaatat ataggaaaat atgcggccga cagcttgctg
     3061 attgtccgga cttatctatt gttcgcactc tcgcttatat tctttcgtgt acaatcgctg
     3121 agcgatgcct ggtatttctt acggaacatc tcgttcgagg tacattcttc ctggaaagaa
     3181 atgaacatcg gcatacgcga tcataattgc atcgtagcag gttcggccct attactagta
     3241 ttgatctacg aatattatgc atctaagtac aacctgatgg aaacacttga acgccaaccc
     3301 gcatggttac ggtggagtgt ctactatctg ttggtattcg ctctgctgat gttaggcaaa
     3361 tttgacacgg aaactttcat ctatttacaa ttttaaccga aaccctttac gcgcatgcta
     3421 catcattcat cgagaatctc ccccaagaca cgtttttgcc tgaagttgct tttactgatc
     3481 ctgccgctga tcccgatagt ggttgtctat tttatgtttg atccttatag ggtattacac
     3541 ccctacaaac gattcgacga ctctcccatg ctactcaacg aagcccatgt gggatggcag
     3601 aattatctgc agaatcgcga ttcgatagcc tataactcct ttatactcgg caactcctgt
     3661 accatggcat tcctgacagg agaatgggaa aagtacctgg ataagaacga ccatgccgta
     3721 cgcttctatg acaacggaga aagcctgggc ggcgtccgtc aaaagcttca gctgctcgac
     3781 tctgtaggtg cacccctgaa aaatgtacta atcgttctgg ataaaaaatc actggacaaa
     3841 aacgctcctt tatcgggcaa caatcatctg ttttcggccg aagcagccgg catcagccaa
     3901 ttgggattcc agttgagatt cctgcaggag ttcctttatc cggacagaat gattccttac
     3961 atagattatc tgatccgaca taagtatgct ccttatatga aaggggttat aaatccggga
     4021 gatcccgtca gggagcctta cacgaacaat tttatcaatc ccagagaaaa agagatcgcg
     4081 caagatggcg aaatatactg gagccgtcat gaaaaagaat tcaagaagcg aacgaatgcg
     4141 ggtatggaag aacttcctgt tatatttgcc agccagattc aggtacttcg ctccatcaaa
     4201 aaaatctgcg ataagcacca cacgaacctg aagttcatca tcggtccgga ttactatcag
     4261 aaaaagacca gccgggaaga cataaaaata ttgaaggcta tactgggtga ttccgctgtc
     4321 tgggatttca cgggaatcaa cgaatacaca gccgacatac atcattatta cgaacccggt
     4381 cattatcgtc cgctgctggg agcacgctta ctgaaagcca tttatcagga tcaagacacc
     4441 tgccacaggc aataaaagtt cctcccataa cagtagcaca cacagaagaa gagcatcctc
     4501 gatccgaaag aaataattat atcaaagaaa acaattatat cacattaaaa acttagatta
     4561 tgaaaaagat tttattattg ctatccgtct gcatttcatt ttcatcatgc tgtacattat
     4621 tcagcagttc caaacaagat atcaccttta cgggaatgaa tggaaccaaa atctacgaag
     4681 catcgaccaa acagaaaata gcggaaatca aagaagacaa tagtgtcact gtacaaatca
     4741 aaaagaaaag ggaagacaaa caactagtag ccaaaaagga agggtaccaa acgactccct
     4801 ttgtcctgga atctacattt aacaatgcct gcctgtggaa cattctattt tggccgggct
     4861 ttctggtaga tttgggtacg caaaagatga acaaatggga taacacaatt atcaatatcg
     4921 aaatggagaa agaaaataca gaaaacaaat gatcaaacta taatttcgca tggcactctt
     4981 ctccttccac ggagggagtc gccatacgga atcatgcgac ctacaaggaa ggcataattc
     5041 accacaagtc aacacagagt tttttataaa agttctttag agaataaatc tactctgtga
     5101 gactctgtgc tactccgttg tatatacgag tttcggcaca ctctctatag ttgtttcaat
     5161 tccctgtata atttctgaat gggaagtccc attacattga agtagctgcc ggatatggat
     5221 tctactccga caaaaccgat ccactcctgc acaccatacg aaccggcttt gtccatgggc
     5281 tgatagtgat cgacataata agcgatttca tcttcatcaa gaatcgcaaa acggacatcc
     5341 gtcacggcag cgaaacattt ttgccattct cgggtagtga gacacacacc ggtaatcact
     5401 tggtgcgatt taccggagag gctccgcaac atctctatgg catcctgcct tccgacaggt
     5461 ttgccgagcg ctttgccttc atgccagaca atggtatcgg ctgtgatcaa aagctcttcc
     5521 ggtccgatca tcgactgata ggcggctgcc ttctcacggg ctatgaaaag aggaatctct
     5581 tcaccttgca acgtatcggg ataagattcg tccacatccg gcaaagtttt tactacataa
     5641 tcgacaccca agcccgtcat cagttctttg cgacgcggag aattagaggc caatacgatt
     5701 ttataacgat ctaagttagc aagcatactg ataaataaat aaggtatata ctggaaatca
     5761 ccatccgaaa gcatcatcgg acaaccattg gccttgtgct ttaagcacct gctccaccac
     5821 atcgcgtcca cagccgtatc ctccatcggc atacgaaatg taacgggcaa tcgctttcac
     5881 ctcgggaacc gcatctttgg gacagcaggg caatccgcac tcacgcatca cttccatatc
     5941 gggaacgtca tcgcccatgt agagtatctc ctcgtccgta agtccgtatt tgtcacggaa
     6001 accacgataa tcgtgtatct tcaccgcaga gccgaagtac agatcggata cccccaaccc
     6061 tataaaacgt ttccgcacga catcgctccg cccacctgta ataatagcga tacgaagccc
     6121 tttttttacg gccaattgga tggcataacc gtcttttaca tttaccgtac gcatcggttc
     6181 acccgacgga tgcaaaggga tgacattggc gctcagcact ccgtctacat cgaaagcaag
     6241 tgcctttatc cgggtaaggt cgtaattgat tgtgctcatt tttatttaat gtttcgggat
     6301 tattgtcttt cgtgaatgct tcggctaagc aactcgtata accgctgcat ggcaggatca
     6361 tcggcaagca tccgcaagtg attgccgatc acattctcgt cataacggat ggccggcccg
     6421 gtctgggccg tcttaggttc cagttcgtgc accttacggg cggtttcatc aatcaacggc
     6481 aacatcacgt caaacggcag attgtatttc ttaagcaact cggcagcaag ggcatacatg
     6541 tgattggtga agttacatgt aaacacggca gccagatgga gacttttacg ctgctccgag
     6601 tcggcatcgt acacacggtt ggacagtgta gaggcaatgg ctttcagaaa cgcggcatct
     6661 tctgccgaag aagcctctat gaagaaagga atctccttaa aatctacctc ccgctgcttg
     6721 ctgaaagtct gcatgggata gaacacaccg taatgcgaga catgtccttc ccagacattc
     6781 atcgggatgc tacctgccgt atgcaccatc aatgcctctt cccgcttacc ttcgacaatg
     6841 ccctgaagaa gttcggcaaa ggcggaatct ttcagtgaaa caatatacag cttcgcatac
     6901 gggttcacct ctgcgaggtc tgtcgtatat tcggcttcca ctttctgtgc cagctcgcgg
     6961 gccgactctt ccgtacggct atacacctgt acgatacgaa aacctttccg atataaggct
     7021 tttgccagat tagtggcaag atttccggca ccgataaata cgatcggcgt atcttctata
     7081 cttcttttca tcgtgttgaa atcaaataca atatacctcc gattatcaat aaagccaaag
     7141 gcagcagata accggacatc gaaccaagca acgaaacaat caggccgatg ttcagcacca
     7201 accacaatcc gagcaatacc aagccgacgg atttatcccg cttaataaac aggaaaatca
     7261 ccgcagtgta aagcaaaaga ttatccttat tcatcaccca gggtatcccc aaagtggaaa
     7321 agtgtatcag tttgtcgatc agatagagca cccccatcac aataagggtg actgctgtgg
     7381 ctttgtaggt atctttattg tttgctttta ccgcactcac cgttacttac ctccgaactt
     7441 attaatatgg attttttccc attgcaaatg gtcttcatta aagggtttac gttccatccc
     7501 tttatgcccg atcgctatga cggacaacac ctgcaactgt aaaggaatgt cgagcacacc
     7561 gcgcacaaat tcatcggaag gcatcccggt ggcagtatac cgctcacgca cctgcaccca
     7621 gcaacttccc aatcccaagt cttcggcctg aagctgaatc ataatagagg caatagaagc
     7681 gtcctcaatc catacatcgc tcgccaaggg atcggcagta acgacaatgg ccaatgccgc
     7741 gtcggcaata aaggccgaag cctgctcttt gcaatgtgaa agttcactga gcaacttttt
     7801 atcatcgact gcaataaact gccagctgtt actgcgcttt gaagtaggag ccatcagggc
     7861 cgctttcagc aaagcgacta catcttcctg agaaagttct tctccggtaa atttccgcat
     7921 gctgcggcga ttttttatta gttcactgaa attttccatg tatctatact ttgcattatt
     7981 tgaatatacc gccagtcacc atagaatgca caaacacacg cgaaccgagg taccgcccgg
     8041 catgcccgtc tatataaggt atgccctgca ggactttgca tgaatcggcg cgctccgtgg
     8101 cgattcgagc gcaaagatag gcaatttatt ccactctcgt caactcgccg gtcagtgaat
     8161 cgatgataaa accatgcacc cggacatctt tcggaataag cggatggttc tctatggaac
     8221 gaaccgtgcc cctgacggac ttcaccggat cgtcgaatcc gcccagccac gaattaaaat
     8281 cgaccccgca gtagcgtatc atgtcgattg tttcggactt gattccccgc tttttcatgt
     8341 gagctatcat ttcgtcgctg ttcatgtggc aagcaccgca atcagaatgg gcaatgacca
     8401 tcacttcttc tactcccaac tcgatgatgg ccaccagcag actacggatg acactgccga
     8461 aaggatggga aatgacggca ccggcattct ttataatctt tacgtctcca ttgtgaattc
     8521 ccaaagcggc gggcaacagt tctgtcaggc gggtatccat acaggaaagg atggcgattt
     8581 tcttatcagg atacttgtta gtgatatact tttcgtatcc cctgttctca acgaactttt
     8641 tgttgaattc aagaatttct tctaacataa tcaaaaacgg attttattgt agtatctcca
     8701 caaagatagt cacaaaacga cagctcaaca aaataagccc tgcaaatgtt gtaaagagaa
     8761 ataaaaaatg taaatttgtc ccgatatgcc attaaaactg actacatatt accaaggaag
     8821 tgagattccg gattttcccg gaaccaatac gtttcattcg aaagagctat ttcagatcta
     8881 cgaagaaact ccgggctaca ccccgcttct gattatggct tcggaagacg gaaaacctgt
     8941 tgcgcgactg cttgctgcca tccgcaaaag catccgcatg tttcctcccg ctttcatcaa
     9001 acgctgcgaa atctatggca cgggcgaata tctgatagcg gaagccgaca aggaaaggat
     9061 attcggcgaa atgctggagc acctcaccac ggaggctttg cggaactcgt ttctaataga
     9121 attccgcaat ctggagaacg ccatgttcgg ctacaaatat ttccggtcca acagatactt
     9181 ccctgtcaac tggctgcggg tacgaaactc gcttcacggc atcgaaaacg ccgaacagcg
     9241 tttcagcccc tcccgtatcc gccagatcaa aaaaggcctg aaaaacggag caaaagtaga
     9301 cgaggcacgt acggtagaag agatacgcga attttcgaat atgctgaggc atctctattc
     9361 gtcccgcatc cgtaaacatt ttcccaacat catctttttc caacacatgg acacccggct
     9421 gattcacagc cggcaggcaa agattttcat cgtccgctac aaagacaaaa ttatcggagg
     9481 ctctgcctgt atctattcgg gaaacgatgc ctatctctgg ttttcgggag gtatgcgaaa
     9541 gacctatgcc ttgcaatacc cgggtatact ggctgtatgg aaagccctcc aggatgccca
     9601 tcaaaacgga ttccgccaca tggagttcat ggacgccgga ctcccattta agaagcacgg
     9661 ctatcgtgac ttcgtgctcc gcttcggtgg caagcaaagc agcacccggc gatggttccg
     9721 tttccgctgg caatggctga acgacctgct gatcaaaata tacgtctgaa catccgcctg
     9781 tctcagggat cagcgccaac cctctccgcc ttttaaacca cccccttagg ttttaaacca
     9841 acgatacctg ccttttaaac ccatgcacct taggttttaa acctattttc accataatta
     9901 attgcagaaa aatttcttta ttaaacaaga attgattttc tttgtgctgt tttataccat
     9961 tccgaaaaga cgattaatac caaaatttaa aaatatagtt atgaagattt cacacattga
    10021 acatttgggc attgccgtaa aaagtatcga agaagccctt ccgtattatg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaactgt agaagatcaa aaagtaagaa cagccttcct
    10141 gaaagtaggt gataccaaaa tcgaattact ggaacccaca tgtccggaaa gtaccatcgc
    10201 gaaattcatt gaaaacaaag gtgcaggtgt tcatcacgta gcattcgcca ttgaagacgg
    10261 cgtagccaat gccctggccg aagccgaaag caaagagatc cgcctgatcg acaaagctcc
    10321 gcgcaaaggt gccgaaggcc tgaacattgc tttccttcac ccgaaatcaa ctctgggcgt
    10381 actgacagaa ctctgcgaac actaaaaaga tgtacgattc ggacgatccg cgccacggac
    10441 aaacggaatt tttctttgca ttaaattccc catccgggtt gtcaatcgtc cggttgtaaa
    10501 tattataacc ctttaaatta agaaaaactc atgagtaacc agcttgaaaa agtaaaagag
    10561 cttattgaac ttcgtgctca ggctcgttta ggtggtggcg aaaaggctat tgaaaaacaa
    10621 cacgccaaag gcaaatatac agcccgcgag cgtattgcac agttgcttga cgaaggtagt
    10681 ttcgaagaac tggatatgtt tgttcaacac agatgtacca atttcggaca agagaaaaaa
    10741 catttcctcg gcgacggtgt ggtaaccggt tatggaacga tagaaggtag attagtatat
    10801 gttttcgcac aagatttcac agtattcggt ggttcactgt cggaaaccat ggcacaaaag
    10861 atctgtaaag taatggatat ggccatgaag atgggtgccc ctgttatcgg tatcaacgac
    10921 tcgggtggcg cacgtattca ggaaggcatc aacgccctgt ccggttatgc tgaaatcttc
    10981 cagcgcaaca tcatggcttc gggtgtcatc ccacagattt caggtatttt cggtccgtgt
    11041 gccggcggtg cggtttactc tcccgccctg acggacttca cgctgatgac ggaaggtaca
    11101 tcttacatgt tcctcaccgg accggctgtt gtgaaaacag taacgggtga agacgtgtct
    11161 caggaagatc tgggtggtgc aagcgtacat gccagcaagt ccggtgtaac tcacttcact
    11221 gccgaaaccg gtgaagaagg tctggcgatt attcgcaagc ttctcagctt tattccgcaa
    11281 aacaacctgg aagaagctcc attggtgaac tgtaccgacc ccatcgaccg tatggacgac
    11341 ctgctgaacg agatcatccc cgacagcccg aacaaaccgt acgatatgta cgaagtgatc
    11401 ggcgccatca tcgataacgg agaattcctg gaagtacaga aagactatgc gaaaaatctt
    11461 attatcggtt ttgcccgtat gaacggacaa tcggtaggtg tggttgccaa tcagcctaaa
    11521 tacctcgccg gagtactcga cagcaatgct tcacgcaaag gtgcacgctt cgttcgcttc
    11581 tgcgacgcat tcaacattcc gctggtgaca ttggtagacg ttccgggatt ccttccaggt
    11641 acgggtcagg aatataatgg tgtaatcctg cacggagcca agttgctgta cgcttatggt
    11701 gaagccactg tgcccaaggt aactgttacc ctgcgtaaat cttacggtgg ttcgcacatc
    11761 gtaatgagtt gcaagcaact ccgcggcgac atgaactatg catggccgac agccgaaatc
    11821 gccgtaatgg gcggtgccgg tgcagtagcg gtattgtatg ccaaagaagc caaagatcag
    11881 gaaaaccctg ctcaattcct ggcagacaag gaagccgagt acactaaact gttcgccaac
    11941 ccgtacaatg cagccaaata cggttacatt gacgatgtta tcgaaccgag aaacactcgt
    12001 ttccgcgtga tccgcgccct gcaacagctg cagaccaaaa aattaaccaa ccctgctaaa
    12061 aagcacggta atattccatt gtaacaaatt aaacatcgat tgttatgaat aagaaaagaa
    12121 tcgggatatt tatcgctctg ctggcaatgg tttgcatggg gctcagggcg caaagtgcca
    12181 ccagtctgag aatcaatgag gttttggtcg tcaacgacca gaactatcag gatgactacg
    12241 gactgcacaa tgcgtggata gagatattca acacctcttt cgcttctgta aatctggaag
    12301 gttgctttct gacgaacgat aaaaacaatc cgaccaaata tcctattccc aaaggcgacg
    12361 tgctgactct gatcaagccg cgccaacatg ctttgttctg ggcagacgga atgcctaacc
    12421 ggggtacgtt ccacgtgaac tttacgctcg acccgaacaa agagaattac attgctttgt
    12481 atgactctaa cggtaaaact ctgattgacg aagtaaccat acccgccggt cagcttgccg
    12541 accgttcata cgctcgcgaa aaagacggaa gtgccaactg ggtagtaaaa ggtgaaggag
    12601 agcacagcta tgtcactccg agcaccaata atatgactat cgacaaaaac ccgaagatcg
    12661 agaacttcaa gaaacacgac tctatcggta tcggtatggc catcatcgcc atgtcggtcg
    12721 tattcatagg tttggtactc ttgtatcttt cattcaaggc ggtaggtaac gtagctgtca
    12781 gactgggtaa gaaaaacgcg atgaaagcca ccggtatcac cgacaagacg gaagcgaagg
    12841 aaaagaacct gggtagccac acaggtgaag aaaccgccgc gatcgccatg gctttgcatg
    12901 aatacctgaa tgacgctcac gacgttgaag acatgatttt gactatcaac aaagtgaaac
    12961 gcacctactc cccctggagt tcgaagatct acacactgcg tcagactccg aaaagataat
    13021 tactaaccct aataaaatga agcaatgaaa caatataaat ataaaatcaa cggcaacctt
    13081 tacaacgtta cagtgaacga tgtagaagat aacatagcca acgttgaagt gaacggaacc
    13141 tcttataaag tagagttgga caagcccgtc aaagccgctc cgaaaacggt gacccgtccg
    13201 gcagccgctc cgaaaacgga aacaggtgct ccggtagtaa ccaaacaacc gacagcttcc
    13261 aaaaaagacg gtgtgaaatc tccgcttccg ggcgttatcc tcgacataaa agtgaaagaa
    13321 ggggataccg tgaagagagg ccagacgatc atcatccttg aggctatgaa gatggaaaac
    13381 aacatcaatg ccaataaaga cggaaaagta gcagaaatta aagttaataa aggagattct
    13441 gtacttgaag gtacagacct cgtaatcatt gaataattat gggagatttc gtatcattct
    13501 tagggaataa ccttgttgac ttctggggat acaccggttt tgcgaacgcg acacccggac
    13561 atcttttcat gttgctaatc ggtctcttct ttatctacct tgccgtagcc aaagaatttg
    13621 aaccgatgct gctgatcccc attggcttcg gtattctgat cggtaatatt ccattcaata
    13681 tggaagccgg attaaaagtg ggtatttacg aagaaggttc ggtactgaac atcctttatc
    13741 aaggagtaac ctccggctgg tatccgccgc tcattttcct gggtatcgga gccatgacgg
    13801 acttctcggc gctgatctcc aaccccaaat tgatgctgat cggagctgct gcgcaattcg
    13861 gtatcttcgg cgcgtatatc attgccctgc tcattgggtt cgaacccaac caggcgggtg
    13921 ctatcggtat cattggcggt gccgacggac cgacggccat cttcctttcg tccaaactgg
    13981 ctcccaacct gatgggtgcc atcgctgtgt cagcctattc ttacatggcg ctggtgccgg
    14041 tgatacagcc acctatcatg cgtgcgctaa ccaccaaaca cgagcgtctg atccgcatga
    14101 aaccaccgag aatcgtatcg catacggaaa aagtaatctt ccccatcgtg ggtctgttgc
    14161 ttacatgctt cctggttcct tcgggtctgc ctttgctggg tatgctgttc ttcggtaatc
    14221 ttctgaaaga aagtggagta acccgtcgtt tggcaaatac ggccagtggt ccgttgatcg
    14281 atgtgatcac tatcctgttg ggactgactg tgggagcttc tacccaagct tcacaattcc
    14341 tcacctggga ttctatcttg atctttatcc tcggtgcatt ctctttcatc atcgcaacag
    14401 cgtcaggtgt catgtttgtc aaattcttca atttattctt gaagaaaggc aataagatca
    14461 atccgctgat cggtaatgca ggtgtatccg ccgtacccga ttcggcacgt atttcacagg
    14521 taatcggttt ggaatatgat ccgaccaact atctgctgat gcacgccatg ggtcctaacg
    14581 tagcgggggt tatcggttcg gctgtagctg ccggtatcct gctcggattc ctcatgtaaa
    14641 cgacattttt ttcattagta aagtagacgt ccttcttttc gcaaagaagg gcgtcttttt
    14701 tttgcgttaa tctatctaaa agatattacg aacctttcgt agaacggata tttttactaa
    14761 cttgcggaca ataaaacaat acgtcctatg agaacaagaa caatgaaacc actcttcctt
    14821 attttctgtc tttgcctcag tcccctactg atgggccaga atcaaaacaa aattcaggaa
    14881 gcaatggcaa actatgacta cgagactgcc gttgaactga taaacaagga acctcccacc
    14941 atcccactgt taatgcagaa agcaaaagcc ctgaaaggaa tcggcagcaa tgcggaagct
    15001 ctacgttcca tccgccaagt gatagcggaa gactccacca accaacaggc acacatcgaa
    15061 gcagcggaat gctgtaaagc aatggccaag tacaacgatg cgctggacta ctaccggaaa
    15121 gccatcagcc tgaatcccaa aaacaagtat gcccgtttgc aattcatcaa cctgctttgc
    15181 aacaccaaaa actatgctga ggcttttgga gaaagttcaa tgatgtccga aacggacagt
    15241 tcggccgtag tgctccacct acaggctcaa agccttgaag ggatgcaaca gatactaccg
    15301 gctatcggtt gctatgaagt cattcaggat aaatatccgg acgattatct ggctgcggcc
    15361 aaactcggaa acctgaacat tgtggctgga tatcccgaat atgccatcca agctaccgaa
    15421 cgctataggg aacgggactc caccaacctg attgtcaacc agcaaaacgc tctcgcctac
    15481 tgccacgccg aacaatatcc gacagccatc aagcgctatg aaaagctgtg ccaacagggg
    15541 gacagcagta cacagacctt atactacctg ggagtcagct attacgcgga tgaatattat
    15601 tacgaagcgc acgcgtgttt cagcaaactg caaaaagaga tggaagaaaa tcccaatctg
    15661 ctctattatc tgggacgttg ctgcgccaag acttcctgga aaaaagaagg catcgaacac
    15721 ctggagaaag ctatcgaact gaccattccc aaagacagca ccatgatccg actttacaaa
    15781 ggcttggtag attgttgtaa actggctcag gatactccaa agcaaatcca ggctctcaga
    15841 gaactgtaca aatatgacaa gacgaaccat aaacttcttt atgacatcgc ttggaactat
    15901 tcatatcaac tcaaagacaa caaatcggcc gaacgttatc tgcaggcttt cttaaaaacc
    15961 cgaaaggcga atgccaggaa agaagaaccg gtgagtgaga aaggggaact tgtactcgga
    16021 cttgaaaatt attacaacgc tgccgaaaat tggctgaaag acttacagaa agaaaagttc
    16081 ttcaaagaag gaataccgtt agaaagtcag aaacaataga atctgtcccc cccatgaaac
    16141 attggatact cctcctctat ctggggttca gcgtagtgct gcaagcccag aacaccgcct
    16201 ccgttcaaga agcaatggca aactatgact ataaaacggt gatcagactg attgatgaag
    16261 aaagtgcatc accacagtta ctcatacaga aagccaaagc tttaaaaggt ttagggcgta
    16321 ccgccgaagc cctgtccact ttgcaacata tcattatcga gctgcccgaa aatcagcagg
    16381 cattggtaga ggcagcagaa tgttgcaggc aattgagcaa atttaacgag gccttggggt
    16441 attatcggaa ggtgatggaa ctcaatcccg aacatattta cgcacacttg caatacaccc
    16501 gcttgttata caactatcag cgatacggcg atgcattgcg tgagagtatc gcattggcca
    16561 ggaaagacag ttccgccacc gtattgcgac tgatggcgga aagcatggaa ggagccggca
    16621 tgccggtaga aagtatgttt tgctatcttt ccatcatcaa gaaatatccc tccgactatc
    16681 tctcggtagc taagctgggc agtatcttca atacaatgaa agattacgaa ggggcaattg
    16741 ccctgacaga ggcataccgc aggacggaca gcaccaatgt agaagtgaac cgtcaaaacg
    16801 cactggcgta ttgtctgcgc aaagaatatc ccaccgccat caaacgttat caggatctga
    16861 ccgcccgggg agacagcaca ctgctgacat gttattacct gggagtcagc tactacgcta
    16921 cgaaagaata ctataaagcg cgcgattggc tactcaaagc aaaatcatgc cagtcacccg
    16981 gcgccaacct actctactat ttgggacgtt cgtgctccaa gacattatgg aaacaagagg
    17041 gaataggata tctgaaccag gctatcgccc tgactatccc cgccgacagt atcatggagc
    17101 gcttatactc aggcttggca gactgctaca ggcaaaccaa gcaaacccgg gaccaaatca
    17161 aggctaccaa agaacaatac aaatatgccc ctgacaagca tattttactt tataacttgg
    17221 cgttcttatc ggacaaaata ggagatacta aagccacaga gcattacttg caggcttttc
    17281 tgcgaacaaa atccaaacaa aatgcagtac tacagcagcc ggatgatgac gaagaagaac
    17341 ccgcacccta catagattac tacaaaagtg ccaccaataa attggaaagc atccgaaaag
    17401 agaaattctt aaagggagaa aagtgaattg atcggataga tgcatcgttt cggacaattc
    17461 accactgagt gcagacagag tttcacagag ggagaataat ggaaaataaa tttgaagatg
    17521 tgcggtagaa ggcacagtag cacgtaaccg aagtcacatc ggcacgcagc cgaaattact
    17581 gtgctgcgta gccgaagtta cggtgctgcg tagccgaagt tacggtgctg cgtagccgaa
    17641 gctatgacgg catctccttt tccggacgtc acgttcacca gattgcatcg aaaagtgctc
    17701 cttatcggtt gagctccatc ccggagaatt ctccaatgaa aacgtttgca taaatagatg
    17761 gcacacagta agaaagaaaa cggaaaacaa tccgatgatt taccctatat tagcaacatt
    17821 aaataataac gagctaatat catgaaaaaa ttattgttac tcttaggttc attcctactg
    17881 tcattaacca cttatgcagc catgaacata tccaaaatcg atccgccctt ctggttcacc
    17941 ggtatgaaca atccggaact ccagttaatg gtatgcggtg aaggcatcgg ccaggcatcc
    18001 gtatcagtaa attatcccgg tgtatcgctc agcagcgtcg tgaaactgga aagcaacaat
    18061 tacctgcttg tctacctgca tctcgataaa gaagtaaagc cgggcaagat gcccatcaca
    18121 tttacggtcg gaaagaagaa attggtgaaa gagtacgaat tgaaagcacg cagcaaagcc
    18181 ggagtcgatc acaaaggttt tgacgcatcg gatgcattat atctgctgat gccggaccgt
    18241 tttgccaatg gcaatccgga taacgaccgg atagaaggca tggccgaata taaagtggac
    18301 cgcaacgacc cgaacgcacg tcacggaggc gacctggccg gtatcgaaca aaatctggac
    18361 tattttaccg acttgggagt gaccgcactc tggttcaccc cggtactcga aaataatatg
    18421 aaaggcggct catatcacgg atatgcaaca accgattatt acaaggtaga cccacgtttc
    18481 ggcactaacg aggaatatcg ctcactgata gcgaaagccc acaaccgggg cattaaggtc
    18541 gtgatggaca tgatcttcaa tcattgcgga gtagaacatc cctggatcaa ggacatgcct
    18601 tcaaaggact ggttcaacca tgcggacttc aagaacaact ttgtacaaac ttcctacaag
    18661 ctgactccac atgtagatcc gtatgcctcg gagtacgatt tcgaccagat gaacaacggc
    18721 tggttcgtgg aagccatgcc tgacctcaac caaaagaacc ctcacgtata caaatacctc
    18781 ttgcagaaca gcctgtggtg gattgagtac gccgatatcg acggcatccg gatggacacc
    18841 tacccgtatg ccgattacga tgccatgagc aactggatga aagaactgaa cgaagaatac
    18901 cccaactaca acacggtggg cgaaacctgg gttaccgaac cggcctatac agcctggtgg
    18961 cagaaagact ccaaactctc cgccccgcgc aacagtcact tgaaaacagt catggatttc
    19021 agcttcttcg acaaagtcaa cacggccaag aatgaacaaa cggacacttg gttcaaagga
    19081 ttggaccgtg tctacaacaa ttttgtatac gattatctgt atcccaatcc ggcttccgta
    19141 ctggctttca tcgaaaatca tgacaccgac cgtttcttgg gtgaaggcga aaacctcgat
    19201 atgctgaaac aggcctccac ccttttattg accacccgac gcatcccgca actctattat
    19261 ggaacggagg tgatgatgaa cggagtaaag agtaaaagcg acggctatgt acgaaaggac
    19321 ttcccgggcg gatgggcgga cgataaagag aatgccctga ctcccgaggg acgtacccga
    19381 ttgcagaatg aaagctataa cttctaccgc aacctgctga actggcgtaa gggcaacgat
    19441 gtgatcgcca aaggcagcat gaaacagttc atggtacagc acggcgtata tgcttatgca
    19501 cgccaatata aagggaaaac ggtatttgtc ctgttgaacg gtacggataa agaggtgaaa
    19561 cttcccctga aatactatgc cgaagtgctg aaagacaaga ctcaaggaaa agacgtcatt
    19621 agcggaaaag taacggcact caatgaagaa ctgacaatgg caccccgcca atcgatggtt
    19681 atagagcttt aatctcacac cggttataac cgcataagca aagggcacaa aggatttcac
    19741 ccgacatcct ctgtgccctt tgtgtagcct aatgcgaata ataatagtca aacgtttgac
    19801 tattatcgga gaatattcct acctttgcag cgactaaaag aatacgacga tgacaaacaa
    19861 cgaatcggag cgcgagctcg tcctacaaac cttacgaacc tggatggcat tccgccaggc
    19921 cgttcagcgg gtactcaaac gtcacaacgt ggatatgacc ttcgagatgc tgcaagtaat
    19981 gaactgcctg tggaacaaac aaggcatcag ccagcaatcc ctggctgaga aaacagcaaa
    20041 ggacaaggct tgcctgacca atctgattaa taatctggaa aagaaaaact gggtgatacg
    20101 gaaagaaggc ccctccgacc gccgaaaccg cctgattttc ctgacgcccc aaggcgaaga
    20161 acttgccctc accgtgaaac ccctgatcaa cgatatctat gcccaaaccg gagcagagat
    20221 ggaggcaagc cggataacgg aatgcatcga agacctgaag agactgcatg aagtgctcaa
    20281 tgagatctaa aagaaatccg ccatgtccac ccatcagata aagctaaaac aattgagaag
    20341 actgaagttc aggaacatct ttctcaacac agtatgcatc ctgctggcat tggcaggtat
    20401 ttcatggaca gtaaactact tctggaaata cgcccgctac gagataacca atgatgccgt
    20461 agtggatcaa tacatcgctc cgctaaacat ccggataccg ggctatatca aagaagtacg
    20521 ttttaccgaa caccagtatg ttcatgccgg cgacacgtta ctgatactgg acgaccggga
    20581 ataccggatc cggctgaaag acgcggaagc ggccttgatg gatgccttgg gatcaaagga
    20641 agtgttaaac tccggcatcc ggacttcagg agtaaatgta gccgtacaag aagccaacat
    20701 agccgaaaca ctggcacgcc tttcacagca agaagcggaa ctgaaccgat atacccggct
    20761 cctgaaaaag caggccgtca gccaacagga ttatgaactg gccaaagcga acttcgaagc
    20821 gacccgggca agatacaacg ccctgttgcg acaaaaagaa gcggcccaat cgcagtattc
    20881 cgaaaccagc aaacgcagta caggcgccga agccaatatc ctccggaagg aggccgacct
    20941 ggagatggcc aaactaaacc tgtcgtatac cgttgtcacc gcaccctatg acggatacac
    21001 gggacgacgt acacttgaac cgggacagtt cgtacaaggc ggacaaactc tttcctacct
    21061 ggtacggggc aatgacaagt gggtgacagc caattataaa gagacacaaa tagcccatat
    21121 ctatatcggg caaaaagtcc gcatcaaagt agatgctttc agcggacgca cttttcacgg
    21181 gaccgtaacc gccatttccg aagccaccgg atcgaaatac tccctggtac cgaccgacaa
    21241 ttcggcaggg aacttcgtca aagtgcagca acgcattccg gtccgcatcg atctcaatga
    21301 cgcctcaccc gaagagatgg aatgcctccg tgcagggatg atggtagaaa cggaagcggt
    21361 ccgcccttag gcttatggtg aagctcaatc tgcctacccg tccctgggtg cctcaatggt
    21421 tgggcatcgt gaccatgttt attgtcatct ttcccatcac cctgctcaac ggtgcctaca
    21481 caggaagtat ggtcgaagta tcgaacacgc tgggagtatt gagcgaagat attaccatgg
    21541 cttactattc agcttcggta gggatggctg ttgcctatcc catcgtaccg aaaatacgca
    21601 ccatagccac tccgaaaacc ttactgctta ccgacctgct gctacagata ttcttcagcc
    21661 tggtatgcgc ccaaaccggt agtatggacg tcatcatggt atgcagtttc tgtatgggat
    21721 ttctcaaagc cttcgtcatg ttggagttca tcatcctgat ccgcccgctc ttcagtccga
    21781 aaaacgtacg aagtgaattc tatgcctact tctaccccat cgttttctcc ggaggtcagc
    21841 tatcgatggc tatcaccgct caactggcct atcactacca atggcagcac atgtactatt
    21901 ttgtcaccat cctcttgctg atcgccattc tgttcgtcat ctgtttcttc cgctatgcaa
    21961 ggcgtcccat gcacattccg ttcaaagaga tggacggaag aagcatgttc atcatcgcca
    22021 ccgctttcct gctaacgctc tatacattta cctacgggaa aacactcgat tggttcgcat
    22081 ccccgaagat cagagtatat gcattcgtca tcccgctcct gatagctctt ttcatccatc
    22141 ggcagcgtac acaaggcaaa ccctttgtca gcctgaaacc actctttctg cataaatcca
    22201 tcatcggata tggcttcatg gtactcgcca tgttcctgac agccaccagt tcactggtaa
    22261 ccaactatat gaacagcatc atccgggtag acagcataca cgccaattcg ctgagcctgt
    22321 ggctattgcc cggatatgtg gtaggagccg tcatttgctt ctggtggttc cgatggcaac
    22381 gatggcggtt tcgcttcctc atttcaggag gtatgttctg ctacgtcatc tatctggcta
    22441 tcctctactt tggtatcacc ccttatggaa cctatgaaat gctctacctc cctatcctgt
    22501 tccggggagt ggggatgatg gtcatattca ttgcgttcgg tgtgtttgtt gtcgaagatt
    22561 tagacccgcg cctgacgttg tccaatgcct tcttcctgat ttcattccgc tcagtattgg
    22621 ctccggtcct gtccgcttcg ttctttaaca acatgcttta ctatctgcag gcaaagggga
    22681 tgaacattct ttcggaaaac atgacgctga ccaatccgct ggccgaacaa aaatacaatc
    22741 aggcattgag caatgccctg gcgcaagggc acgaattcag cgaggccgga caattggcag
    22801 ccaacagtct gtactccact ttgcagcagc aatccctgct gcttgccctg aaaaccctaa
    22861 tcggctatgt actgatactg gcactggtga ttgctgtcat cgcagcgttc attcctttcc
    22921 ataaaacgct gaaggtggct gttgtgaaga cgggtgacga tatggtataa tgagaaggga
    22981 tacaaaaaag ccactcaatt gcttgagtgg cttcttaaaa tataaattaa atcaagtaaa
    23041 acttttaaat actagatttg gaatttattc agctaacttg ttgtcagaac ccagcacgtt
    23101 gataattttg tgcttgtaga gtttttccat attgtcgcga gccggtccca gatatttacg
    23161 cgggtcgaac tcagccggtt tttctgcgaa taccttacgg atagcagcag tcatagccag
    23221 gcgagagtct gagtcgatgt tgattttgca aacagcagac ttagcggctt tacgcagttc
    23281 ctcttcagga ataccgatag cagctttcag tgcaccacca aactggttga tagttgcaac
    23341 ctcttcttca ggaactgaag atgatccgtg aagaacgata gggaatcccg gaagttcttt
    23401 cattacaccg tccaatacgt cgaatgccaa cggaggagga accatacggc ctgtcttcgg
    23461 atcgatgtgg cactgttccg gagtaaattt gtaagcaccg tgagaagtac cgatagagat
    23521 agccaatgaa tcgcaacctg tcttggtaac gaaatcaact acttcgtccg gttcagtata
    23581 tgtgtggtgg tcagaagaaa cttcgtcttc tacacctgcc aatacgccaa gttcaccttc
    23641 tacagttaca tcgaactggt gagcgtattc aacaactttc ttagtcagag caacgttttc
    23701 gtcgtaagga aggtgagaac cgtcgatcat tacagaagag aagcctgagt cgatacagct
    23761 tttgcaagtt tcgaaagtat ctccgtggtc gaggtgcaaa acgatttcag gatttttgca
    23821 gccgagttct tttgcatatt ctacagcacc ctgagccatg taacgcaaca atgtagcgtt
    23881 agcatactga cgagcacctt ttgatacctg caaaataacc ggagacttag tttctacagc
    23941 agccttgatg atagcctgca tctgttccat attgttgaag ttgaatgcag ggattgcata
    24001 tccacccttg atagccttag caaacatatc tctagtgttt accagaccta aatctttgta
    24061 attaaccatt ttgtttaaaa gtttattgtt agtgaattaa aaattctatg caaaagtaag
    24121 aataatcctt tgaatagaga aaccctcggg cggaaatatc cgtttgagga gcgtaattca
    24181 attctatttc aaattatttc ccatccttta agagctgttt gtaatgtcta cgtagcaaat
    24241 aaaggttttt tattgtttcc tcatatatat aatggtaggc aaatgatcgc tgtaaccatc
    24301 caaccacact ctgccaccat atgtacgcag gggtgcaccc ttatatttac catcctgctg
    24361 aaacaggtaa tcgcgcatga aaacttcatt gtgatcatat ttcaatcctt ttgtggcttg
    24421 aagcagcgtg ggcgaaagga tgatctgatc gaacagattc catttgccgc gatagagcaa
    24481 agtgcccact cccttatctt ccagcgtcac ccaccagggg ttgtaaaggt catcttcagt
    24541 catatcttcg acgtgtttct ttgcccccag tacggcaagg ctcaagtcca tcggatcatc
    24601 gttgaggtcg cccatgataa tcagcttcaa gtccggatc
//
