LOCUS       c00008_gnlPro..        11489 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKHFACLO_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 02:24:52
            Original ID  :: gnl|Prokka|AKHFACLO_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11489
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11489
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3259](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(2..3259)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..11489
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11489
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(2..3259)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="HGD-D (E-value: 2.4e-18, bitscore: 55.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 4.6e-40, bitscore:
                     126.8, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDTANTAAESHDSKPLRVGLDIGSTTVKAVVLDQTNALNDVLFS
                     DYRRHHANVRATVAGLLKDIHQTLVDLGRGDEPIRLAITGSGGLTLADNLHVPFIQEVI
                     AETRAIDEEYPQADVIIELGGEDAKITYLKPTPEQRMNGSCAGGTGAFIDQMATLLDTD
                     ASGLNDYAKDYKTLYPIASRCGVFAKTDLQPLINDGAAKPDLAASIFTAVATQTIAGLA
                     SGRPIHGTVIFLGGPLFFMSELREAFHRALAGKVDEFIVPTDAHLYVAYGSALIAGEPD
                     GIDVDGVHFEPRTCDDIIAALDDLKNLPANTPTMPPLFSSDQEREAFNERHHREHIHIG
                     TLEGAKGPHFLGIDAGSTTIKATLVNDDREIVWSSYATNEGSPLTAAINIVKKIQSELP
                     ESAWIARSCATGYGEGLITTGLHLDEGVVETMAHYRGAEMVSPGVTAVIDIGGQDMKYL
                     AITDGVIDSIAVNEACSSGCGSFLQTFAQSMGLTIQEFTQAALNSDHPVDLGSRCTVFM
                     NSSVKQAQKEGASMENIAAGLCYSVVRNALYKVIKLRDSGELGDTVVVQGGTFLNDAVL
                     RAFELLTEREVTRPNIAGLMGAFGAALTARMHYEDVADDAHDHDAEVSAGQSADMAGSD
                     DVSAEQDHEVVIDGVHHTASNILSGDDLDNMSMTSERDVCKLCQNHCKLTITTFADGSR
                     YVTGNRCERGGDAKKKRSDRPNLYDYKYKRCFAYRRLTDKKATRGEIGIPRVLNMYENY
                     PFWFTLLTSLGFKVMISGRSSHELFETGIESIASENICYPAKLVHGHIKWLLGKGVKNI
                     FYPCVSYENNLVPNTDNHYNCPVVANYPVVIGANMPELREDGIRYMHPYFNLANHELMV
                     DRIVEEFAWANVSREEAETAVKAAYAEDKIFKNDVQEEGFKALAYMKEHNCRGIVLAGR
                     PYHIDPEVNHGIPETICALGMVVLSEDSICELQPGENLHLSDYLSEGEEDPRKKNANGF
                     RHVGDRKVTVSRMPLRVTNQWAYHSRLYAAAHFVASYPGLELVQLNSFGCGLDAITTDQ
                     VAEILADKADVYTLLKIDEVSNLGAAKIRLRSLKAAVE"
     CDS             complement(3413..3760)
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MALLLPAFIWPRVSPLFHVMMLCFREGCSRMLGTGLGRTTLYMRG
                     VRDGVVDVFAGSSVPGPLEVSDTAAGVWPSVVAGVSAISGIWAGLGWSIALVHKTTSLL
                     ACSAHPPPNAR"
     CDS             complement(3848..4555)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 166;
                     E-value: 1.9e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="Fer4_12 (E-value: 2.5e-52, bitscore:
                     166.0, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRKSTLHDFAAGETGRGPGVPSSLTNNPRSGQWDGRRMSKRMIA
                     DYKTFIVTDGEGVRNSLYVSGCPFHCVECFNSSIWDFQAGHEYTQKLEDKIVDDLKAPW
                     IQGITFLGGEPMLNTPVLLPLARRIRGEFGHDKDIWCWTGYTWEELMRPGETPDKLELL
                     QLIDILVDGRYLKDQHDSLLQFRGSRNQRILDVPRSLAAGRPVVWAKLHDQERDIPEMY
                     LKDREAGEGAQAS"
     CDS             complement(4710..7094)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NRDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="NRDD (E-value: 1.6e-170, bitscore: 557.6,
                     seeds: 337, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALLMNASTATSSKVLVEKRDGRVVDFDPINIISAVKSAFADLD
                     KQVGPEEEKLIRGFADQIEGEITERYNGPAKIEDIQNLVEHALIDAHLYDVARAYTNYR
                     LDKDIQRAKATDVNEAVSRFINQDPTLIHENANKDANVYATQRDLLAGAVSKAAAFNML
                     PPAVANAHMKGDIHFHDADYSPFTAQSNCSLPNFWDMLANGFTLGNAPMASPKSIAIAA
                     TQITQIMKDVASSQYGGQTANRADEHLAAYAKKDYEKFLEEARETIPDGMPVEFARRQV
                     ENAKANEPAKLHFGSREPLPMDTPFHTDVDELEQEREILAKVRTRKSIYDAMQTMEYQI
                     NSNRVSNGQTPFVTVGFGLGTDWFAREVQRAILLNRIRGLGKDHHTAIFPKLVFTVRHG
                     VNADPGDPNYDLKQLALECATKRMYPDVVFYENIVKITGSFKAPMGCRSFLQGWINPET
                     GKDEEDGRMNLGVVSVNVPRIAIESHGSKERFWKLFNERMEVAHQALQFRIMRCKQATP
                     VNAPTLFRFGAFGRLGASGNVDTLFKNERATVSLGYIGLAEATAVFYGKDWIRDHGWDP
                     QGKEFALSIVKRMSELCKQWSKAEGYHYSVYSTPAESLTDRFNRMDREKFGRIEGVTDH
                     DFYTNSFHYPVWLQPTPMEKLNYEKDFPYFASGGFINYCEYPCLQDNPKALEAVWDYAY
                     NIGIGYLGTNTPIDHCFVCGFQGDFEPTDEGFKCPECGNCDPDKCNVTKRTCGYLGNPV
                     QRPMVHGRHEEISHRVKHMSGETGHVTLADGSEREWFEEAK"
     CDS             7391..8716
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="LSFLYVNLEGMNQEQDLAIATQRPSEGGGERIPKPFDQLPRLAAE
                     TTADNPWPVSVLSQKFHTAVERWPAAWIAGQITEINTRRAGSAYLTVRDDMEDIAISVS
                     GWRAFASKAASFKQGDRVVVHGKADIWVKQTRLSFIGDDIRKIGSGGGLKEQIDQLRMK
                     LKGEGLFDADRKVPLPEFPSCIGLICAPHARAEGDVITNVRLRWPTVRFNIVHAFVQGP
                     QCPQSIVEAIHRLDADPDVDVIIVARGGGSFEDLIGFSDEAVVRATAGCETPIVSAIGH
                     EDDWTLIDLAADLRASTPTDAAKKVVPDVHEQWQLIGNAIDRMRMRIDARVGNEIRLVE
                     GYANRPSLTQPLTMLEPYQRFVDDARRRMDIGLTRIVDDASLTVEKLHASLTALSPQST
                     LDRGYAVVQNADGHVIDDAGKVSAGDHLTLTLRKGVITATAQ"
     CDS             8828..9127
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MTSKNASAASEPATSLTDKEREAIAQMPYEEARDKLIQAVQALEA
                     GGLNLDQSMRQWEIGEALAKRAQSLLNEVKAKLDAAQAEQANSADTAGTQSNLD"
     CDS             complement(9432..10361)
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MLPEDLQALPYIPVIVSATPWFVILAVLALILSVISRRWIAMLMA
                     LACIGLQVWWQWPFFSASTKLPAAVDAAMASTRADTGDMIARVMTFNVYKGHADAKAIV
                     DIVRDQRVEVLALQETTNDFIKKLDEAGIHSYLPYSQVSSSDGVYGNGIWSATELRRPV
                     DDEVGSSASFMPGGTVTFGGGKAQLRFVSVHTTAPIPGYWSRWKRSLDELASMRSREGS
                     RYVFMGDFNATTDHTPFRNILGNRFSDAARQSGHGFTFTWPSNKLPLPRFAGIDHIVLD
                     KDIIAGQMQVKSVAGSDHAALLATIVVQ"
     CDS             11278..11439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LacI"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_8"
                     /sec_met_domain="LacI (E-value: 3.1e-17, bitscore: 51.4,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATLKDVAKAAGVSPSTVSYTLRGGAYVSQETPGQICAIIERNKN
                     TTPVDILH"
ORIGIN
        1 cctcgacggc ggccttgagc gaacgcaggc ggatcttcgc cgctccgagg ttgctcacct
       61 catcgatctt gagcagcgtg tacacgtcgg ccttgtcggc gaggatctcg gccacctgat
      121 cggtggtgat ggcgtccagg ccgcagccga aggagttgag ctgcacgagt tcgagacccg
      181 ggtaggacgc cacgaaatgc gccgccgcgt agagccgcga atggtaggcc cactggttgg
      241 tgacgcgcag cggcatgcgg gagacggtca ccttgcggtc gccgacgtgg cggaagccgt
      301 tcgcattctt cttgcgcggg tcctcctcgc cttctgacag gtagtcgctc agatgcaggt
      361 tctcccccgg ctgcagttcg cagatcgaat cctccgagag cacgaccatg ccgagcgcgc
      421 agatcgtctc ggggatgccg tggttgacct cggggtcgat gtggtacggg cgtccggcga
      481 gcacgatgcc ccggcagtta tgctccttca tgtaggcgag cgccttgaaa ccttcctcct
      541 gcacgtcgtt cttgaagatc ttgtcctcgg cgtacgcggc cttgaccgcg gtctcggcct
      601 cctcgcggct cacgttcgcc caggcgaact cctcgacgat gcggtcgacc atgagctcgt
      661 ggttggcgag gttgaagtac gggtgcatgt agcggatgcc gtcctcgcgc agttcgggca
      721 tgttcgcgcc gatcaccacc gggtagttgg ccacgaccgg gcagttgtag tggttgtccg
      781 tgttgggcac gaggttgttc tcgtagctca cgcacgggta gaagatgttc ttgacgccct
      841 tgcccagcag ccacttgatg tggccgtgca ccagcttggc cgggtagcag atgttctcgg
      901 aggcgatcga ttcgatgccg gtctcgaaca gctcgtgcga gctgcggccg gagatcatca
      961 ccttgaagcc gagcgaggtg agcagcgtga accagaacgg gtagttctcg tacatgttga
     1021 gcacgcgcgg gatgccgatc tcgccgcggg tggccttctt gtcggtgagc ctgcggtagg
     1081 cgaagcagcg cttgtacttg tagtcgtaca ggttcggcct gtcggagcgc ttcttcttcg
     1141 cgtcgccgcc gcgctcgcag cggttgccgg taacgtagcg cgagccgtcg gcgaacgtgg
     1201 tgatggtgag cttgcagtgg ttctggcaca gcttgcacac gtcgcgctcg gaggtcatcg
     1261 acatgttgtc gaggtcgtcg ccggacagga tgttggacgc cgtgtggtgc acgccgtcga
     1321 tgacgacctc gtggtcttgc tccgcgctga catcgtcgct gccggccata tcggcggact
     1381 ggcccgcgga gacttcggcg tcgtggtcgt gcgcgtcgtc ggccacgtcc tcgtaatgca
     1441 tgcgtgcggt cagggcggcg ccgaacgcgc ccatcaaacc ggcgatgttc gggcgggtca
     1501 cctcgcgctc ggtgagcagc tcgaaggcgc gcagcacggc gtcattgagg aacgtgccgc
     1561 cctgcacgac gacggtgtcg ccgagctcac cggagtcacg cagcttgatg accttgtaca
     1621 gcgcgttgcg cacgaccgaa tagcacaggc cggcggcgat gttctccatc gacgcgcctt
     1681 ccttctgtgc ctgcttgacg gacgagttca tgaacaccgt gcagcgcgag ccgaggtcga
     1741 ccggatggtc ggagttgagg gccgcctggg tgaactcctg gatggtcaga cccatcgact
     1801 gcgcgaaggt ctgcaggaac gagccgcaac cggacgagca cgcctcgttg acggcgatcg
     1861 agtcgatgac gccgtcggtg atggccaggt atttcatgtc ctggccaccg atgtcgatga
     1921 cagcggtgac gccggggctg accatttcgg cgccgcggta gtgcgccatg gtctcgacca
     1981 cgccctcgtc caggtgcaag ccggtggtga tcagtccctc gccgtagccg gtcgcgcagg
     2041 atcgggcgat ccacgcgctt tcgggcagct cggactggat cttcttgacg atgttgatgg
     2101 cggcggtcaa cgggctgcct tcgttggtgg cgtagctgga ccatacgatc tcgcggtcgt
     2161 cgttgacgag cgtcgccttg atggtggtcg aacccgcgtc gataccgagg aagtgcgggc
     2221 ctttcgcgcc ttcgagcgtg ccgatgtgga tgtgttcgcg atggtggcgc tcgttgaacg
     2281 cctcgcgctc ctggtcggag gagaacagcg ggggcatggt cggcgtgttc gccggcaggt
     2341 tcttcaggtc gtcgagggcg gcgatgatgt cgtcacaggt gcgcggctcg aaatgcacgc
     2401 cgtcgacgtc gatgccatcc ggctccccag cgatcagcgc ggagccgtat gcgacgtaca
     2461 ggtgggcgtc ggtcggcacg atgaactcgt cgaccttgcc ggcgagcgcg cggtggaacg
     2521 cctcgcgcag ctcggacatg aagaacagcg ggccgccgag gaagatgacc gtgccgtgga
     2581 tcgggcgtcc ggaagccaga ccggcgatgg tctgcgtggc caccgcggtg aagatcgacg
     2641 cggccagatc gggcttggcg gcgccgtcgt tgattagcgg ctgcaggtcg gtcttcgcga
     2701 acacgccgca acgcgacgcg atcgggtaca gggtcttgta gtccttggca taatcgttga
     2761 ggccggaggc gtcggtgtcg agcagcgtgg ccatctggtc gatgaatgcg ccggtgccgc
     2821 ccgcgcacga accgttcatg cgctgttcgg gagtgggctt cagatacgtg atcttggcgt
     2881 cctcgccgcc gagctcgatg atgacgtcgg cctgcgggta ttcctcgtcg atcgcgcggg
     2941 tctcggcgat gacctcttgg atgaacggca cgtgcaggtt gtcggcgagc gtcaggccgc
     3001 cggacccggt gatggcgaga cgaatgggct cgtcgccgcg gccgaggtcg acgagcgtct
     3061 gatggatgtc cttgagcagt ccagccaccg tggcgcggac gttggcgtgg tgacgccggt
     3121 agtcggagaa cagcacgtca ttgagcgcat tggtctgatc gagcaccacg gccttgaccg
     3181 tggtcgatcc gatatccaga cccacgcgca acggcttact atcgtggctt tcggccgcgg
     3241 tattcgctgt atccaccatc tgttacctct gtcttcgatt cgggacttcc cgctacttcc
     3301 ttatgtaatg tagtccgaga cccctcctaa cgagccgtcg tatggcgtga tttcgctaac
     3361 aaacgcaaaa cggaaactcg acggtttccc cacgattgcg gcgttacccc cattatcgcg
     3421 cattcggggg ggggtgagcc gagcatgcca gcaggctggt ggtcttatgg accagcgcta
     3481 ttgaccaccc cagtcccgcc caaatccctg atatggcgga cacgccggcg acgacggagg
     3541 gccatacccc ggccgcagta tccgagacct ccagcggacc gggcacgctg ctgcccgcga
     3601 aaacgtcgac cacgccgtcc cgcacgccgc gcatatacag agtcgtccgc cccaatccgg
     3661 tgcccagcat gcgcgagcac ccttcccgga aacagagcat catcacatgg aacagcggac
     3721 tcacgcgagg ccagatgaat gcggggagaa gcaaggccat gccgatggcg ggcgagactg
     3781 tcaggatggc cgcgatcagg ccgacggcat cgaatccact ggatggatgg caaggccggc
     3841 ggcgccgtca cgacgcctgc gcgccctcgc cggcctcgcg atccttgagg tacatttcgg
     3901 ggatgtcgcg ctcctgatcg tggagcttgg cccagacgac aggcctgccg gcggccagcg
     3961 aacgcggcac gtcgaggatg cgctggtttc tggatccgcg gaactgcagg agggagtcgt
     4021 gctggtcctt gaggtagcgg ccgtcgacga ggatgtcgat gagctgcaac agttctagct
     4081 tgtccggcgt ctcaccgggg cgcatcagct cctcccacgt gtagccggtc cagcaccaga
     4141 tgtctttgtc gtggccgaac tcgccgcgga tgcgccgggc gagcggcaac aggacgggcg
     4201 tattcagcat gggttcgcca ccgaggaacg tgatgccctg gatccacggc gccttgaggt
     4261 cgtcgacgat cttgtcttca agcttctgcg tgtattcgtg gccggcctgg aaatcccaga
     4321 tcgacgagtt gaagcattcg acgcagtgga acgggcagcc ggagacgtac agcgaattgc
     4381 gtacgccttc gccgtcggtg acgatgaagg tcttgtagtc ggcgatcatg cgcttggaca
     4441 tgcgccgccc gtcccactgg ccggaacggg ggttgttggt cagtgatgac ggcactccgg
     4501 gtccgcggcc ggtctcgccg gccgcgaaat catgcagcgt cgacttcctg tccatcatca
     4561 tcctccctgt ccaaccgtaa cgttgcgcgc aacgagcgag ggtcgccggt atatgttgtc
     4621 tgaccgtaag ctcggccgaa cggccttgag tgtgtcagac aacatatacc gacgaccctc
     4681 gcggacagca caacgcgcgg taccggcagt tacttggcct cttcgaacca ctcgcgctcg
     4741 gagccgtccg ccagcgtcac gtgaccggtc tcgccgctca tgtgcttgac gcggtgggag
     4801 atctcctcgt gacggccatg caccatcggg cgctgcaccg ggttgccgag gtagccgcag
     4861 gtgcgcttgg tgacgttgca cttgtcaggg tcgcagttgc cgcactcggg gcacttgaag
     4921 ccctcgtcgg tcggctcgaa gtcgccctgg aagccgcaca cgaagcagtg gtcgatcggc
     4981 gtgttggtgc cgaggtagcc gatgccgatg ttgtaggcgt aatcccacac ggcctccagc
     5041 gccttcgggt tgtcctgcag gcacgggtac tcgcagtagt tgatgaagcc gccggacgcg
     5101 aagtacggga agtccttctc gtagttgagc ttctccatcg gggtgggctg cagccacacc
     5161 gggtagtgga aggagttggt gtagaagtcg tggtcggtga cgccctcgat gcggccgaac
     5221 ttctcgcggt ccatgcggtt gaagcggtcg gtgagggatt cggccggtgt ggagtacacg
     5281 gagtaatggt agccttcggc cttgctccac tgcttgcaca gttcgctcat gcgcttgacg
     5341 atcgacagcg cgaactcctt gccctgcggg tcccagccgt ggtcgcggat ccagtccttg
     5401 ccgtagaaga cggcggtggc ctcggccaag ccgatgtagc cgagcgacac ggtggcgcgc
     5461 tcgttcttga acagcgtgtc gacgttgccg ctcgcgccga ggcggccgaa ggcgccgaag
     5521 cggaacaggg tgggcgcgtt gaccggggtg gcctgcttgc agcgcatgat gcggaactgc
     5581 agcgcctggt gggcgacctc catgcgctcg ttgaacagct tccagaagcg ttccttgctg
     5641 ccgtgggatt cgatggcgat gcgcggcacg ttcacggaaa cgacgccgag gttcatgcgg
     5701 ccatcctcct catccttgcc ggtctcgggg ttgatccagc cctgcaggaa ggagcggcag
     5761 cccatcggcg ccttgaagga gccggtgatc ttgacgatgt tctcgtagaa cacgacgtcc
     5821 gggtacatgc gcttggtggc gcattccaag gcgagctgct tcaggtcgta gttcgggtcg
     5881 ccggggtcgg cgttcacacc gtggcgcacg gtgaacacga gcttcgggaa gattgcggtg
     5941 tggtggtcct tgccgaggcc gcggatgcgg ttgagcagga tcgcgcgctg cacctcgcgg
     6001 gcgaaccagt cggtgcccag gccgaagccg acggtgacga acggggtctg gccgttggag
     6061 acgcggttgg agttgatctg gtactccatc gtttgcatgg cgtcgtagat ggacttgcgc
     6121 gtgcggacct tggcgaggat ctcacgctcc tgctccagct cgtcgacgtc ggtgtggaac
     6181 ggcgtgtcca tgggcagcgg ctcgcgggag ccgaagtgca gcttggcggg ctcgttggcc
     6241 ttggcgttct cgacctgacg acgggcgaac tccaccggca tgccgtcggg gatggtctcg
     6301 cgggcctctt cgaggaactt ctcgtagtcc ttcttcgcgt aggcggcgag gtgctcgtcg
     6361 gcacggttgg cggtctggcc gccgtactgg ctggaggcca cgtccttcat gatctgggtg
     6421 atctgcgtgg cggcgatggc gatggacttc ggggaggcca tcggcgcgtt gccaagcgtg
     6481 aagccgttgg cgagcatgtc ccagaagttg ggcagcgagc agttggactg cgcggtgaac
     6541 ggcgagtagt cggcgtcgtg gaagtggatg tcgcccttca tgtgcgcgtt cgcgacggcc
     6601 gggggcagca tgttgaacgc ggcggccttg gagacggcgc cggcgagcag gtcgcgctga
     6661 gtggcgtaga cgttggcatc cttgttcgcg ttctcgtgga tcagcgtcgg atcctggttg
     6721 atgaagcggg agacggcctc gttgacgtcc gtggccttgg cgcgctggat gtccttgtcg
     6781 agacggtagt tggtgtaggc gcgggccacg tcgtacaggt gggcgtcgat cagggcgtgc
     6841 tcgacgaggt tctggatgtc ctcgatcttg gcggggccgt tgtagcgctc cgtgatctcg
     6901 ccttcgatct ggtcggcgaa gccgcggatc agcttctcct cctccgggcc gacctgcttg
     6961 tcaaggtcgg cgaaggcgga cttcacggcg ctgatgatgt ttatcgggtc gaagtcgacg
     7021 acgcgaccgt cacgcttctc caccagcacc ttggaggagg tggcggtact ggcgttcatc
     7081 agcagagcat ccatgtccta atccctgtcc tttcgtgatt cccggcatgt cttgcggcgg
     7141 tcaccgagcc gaaatcacac gtgtgtaagt tgtttgttct ctgatgacta tacgacatgc
     7201 cacccctaga tatagtgggg aaacgccgaa aacaatccta gatatgcaca tttcggcgaa
     7261 atagagccga aaagaacatc cgtgtgattt acttcacggt atgtcgtcag cgtgtcgcgg
     7321 cgagaccatc accgaaaagc cggccaacaa tgataccgtc cgacggcgac gctctcgcag
     7381 gcagaaaaac ttgtcctttc tgtacgtaaa ccttgaaggc atgaatcagg aacaggacct
     7441 tgcaatcgcg acgcagcggc cgtcggaggg cggcggggaa cgcatcccca agcccttcga
     7501 ccaactgccg cgcctggcag ccgagaccac cgcggacaac ccctggccgg tcagcgtact
     7561 gagccagaaa ttccataccg cggtggagcg ctggcccgcc gcgtggatcg ccgggcagat
     7621 cacggagatc aacacgcgcc gcgccggctc ggcgtatctt acggtgcgcg atgacatgga
     7681 ggacatcgcc atatccgtgt ccggctggcg ggcgttcgcc tcgaaggccg cctcattcaa
     7741 gcagggcgac cgcgtggtcg tgcatggcaa ggccgacatc tgggtcaagc agacgcggtt
     7801 gagcttcatc ggcgacgaca tccgcaagat cggctccggc ggcggactga aggagcagat
     7861 cgaccagttg cgcatgaagc tcaagggcga gggcctgttc gacgcggacc gcaaggtgcc
     7921 gctgccggaa ttcccctcct gcatcggact gatatgcgcc ccgcacgcac gggccgaagg
     7981 cgatgtcatc accaacgtgc ggctgcgctg gccgacggtg cggttcaaca tcgtccatgc
     8041 cttcgtacaa gggccgcagt gcccgcaatc catcgtcgag gcgattcacc ggctagacgc
     8101 cgacccggac gtcgacgtga tcatcgtggc gcgaggcggc ggctcgttcg aggacctcat
     8161 cggattctcg gacgaggcgg tggtgcgcgc cacggcggga tgcgagacgc cgatcgtctc
     8221 cgccatcggg catgaggacg actggacgct gatcgacctg gcggcggacc tgcgggcctc
     8281 gacgccgacc gacgcggcga agaaggtcgt gcccgacgtg cacgagcagt ggcagctgat
     8341 cggcaatgcc atcgaccgca tgcgcatgcg catcgacgcg cgcgtcggca acgagatacg
     8401 gttggtcgaa gggtacgcga accggcccag cctgacgcag ccgctgacca tgctggagcc
     8461 gtaccaacgg ttcgtcgacg acgcgcgccg ccgcatggac atcggcctga cgcgcatcgt
     8521 ggacgacgcc agcctgaccg tggagaagct gcatgccagc ctgaccgcgc tcagcccgca
     8581 atccacgctc gaccgcggat acgccgtcgt ccagaacgcc gacgggcacg tcatcgacga
     8641 cgccggaaag gtgagcgcgg gagaccatct cacgctgacg ctgcgcaagg gggtcatcac
     8701 cgccaccgcc cagtagcgga gtgccgcacg gcagcagagt gcggggcaga tatcagccgc
     8761 ataaccatat atatatgacc gttatccaat cgaatacgac acgcatacac gacagaagga
     8821 gaccatcatg accagcaaga acgcatcggc ggcgagcgag ccggcgacca gcctgaccga
     8881 caaggagcgc gaggccatcg cgcagatgcc gtacgaggag gcccgcgaca agctcatcca
     8941 ggccgtgcag gcgctggagg ccggcggatt gaacctcgac cagtccatgc gccagtggga
     9001 gatcggcgaa gcgcttgcca agcgtgcgca gagcctgctg aacgaggtca aggccaagct
     9061 cgacgccgcc caggccgagc aggccaacag cgccgacacc gccggcaccc aatccaacct
     9121 ggactgacgg ggcaccctac gcgggacgtt gcgtccataa gcgcacgcgc cacggcgaag
     9181 tccgcgcgaa cttatggacg gaaaacacga ggtttgcgcc catatgtgcg cgcagccgtc
     9241 gtttgggcga gcacttatgg acgcaacgat ggcgtgccga gaccatctat gtccccatat
     9301 gcgtggtgac gcaccgccgt agtgccacgc accgtagtcg cactacgcgg catccgtcat
     9361 cacccgacgc ctaccacaac atgacaacgt cgccgtaagg taccgcccca atcagccggc
     9421 cgtcaccgcc gtcactgcac gacgatggtg gcgagcagcg cggcgtgatc cgagccggcg
     9481 accgacttga cctgcatctg accggcgatg atgtccttgt ccagcacgat atggtcgatg
     9541 ccggcgaacc gcggcagcgg cagcttgttg gacggccagg tgaacgtgaa cccgtgcccc
     9601 gactgccgcg cggcgtccga gaaccggttc cccaggatgt tgcggaacgg cgtgtggtcg
     9661 gtcgtggcgt tgaaatcgcc catgaacacg tagcgcgaac cttcgcgcga gcgcatggat
     9721 gccagctcgt ccaacgagcg cttccaccgg ctccagtagc cgggaatcgg cgcggtggta
     9781 tgcacggaga cgaatcgcag ctgggccttg ccgccgccga acgtcacggt gccgcccggc
     9841 atgaacgacg cgctcgaccc gacctcgtca tcgaccggac gcctgagctc ggtcgcggac
     9901 cagatgccgt tgccgtagac accgtccgac gacgaaacct gcgaatacgg cagatagctg
     9961 tggatgcccg cctcgtcgag cttcttgatg aaatcgttcg tcgtctcctg caacgcgagc
    10021 acttcgacgc gctgatcccg cacgatgtcg acgatggcct tcgcgtccgc atggcctttg
    10081 tagacgttga aggtcatcac gcgggcgatc atgtcgccgg tgtccgcccg ggtcgatgcc
    10141 atggccgcgt cgacggccgc cggcagcttc gtggacgcgc tgaagaacgg ccactgccac
    10201 cacacctgga ggccgatgca ggcgagcgcc atcagcatgg cgatccagcg gcgcgagatg
    10261 accgacagta tcagcgcgag cacggcgaga atcacgaacc acggcgtcgc ggatacgatc
    10321 acggggatgt acggcagcgc ctgcaggtcc tcggggagca tgcgcaggac gctgcacgcc
    10381 aatgcgagag cggcgaatat gaccgacaag acgccaagga gacggtggcg tcggccgcgt
    10441 ggggcgcttg ttttcgcggc gggccttttc gcagtgccgg acgacgcgcc ggaccgccga
    10501 gccgccgagc cgtaggcgtt ccgtgatgat cctcgcgcgt ttgccattcg ccactcccct
    10561 gtcgtccgtc aaccggtacg caacgacatg tattcttcca gccgtcgcgc atacaagctc
    10621 atacgataac gccccggaac cgcggacgcc atcgttcccg agaatcattc cccattccgg
    10681 cacgtatgcg cggcggcctg cgggcttcac actgcgcacg atacgcgcat atccgcccga
    10741 catgtataat ggtcattcgt tgccccggta gctcagggga tagagcaccg ctctcctaaa
    10801 gcgggtgtcg tgcgttcgaa tcgcatccgg ggcacccatt cgactggaag acccgagcag
    10861 aacgagcgga actgtgcccg ctgatatcaa cgggcacggt ttaccggatc attcggtcat
    10921 ccttgaataa ctatcgagtc tatcgcccgg atcccaatcc ccgcgcatcc ataccatacg
    10981 agacatttcg ggaatatacc gtcactgtgc gagggtgccg tcactctgcg agttttgaga
    11041 gcgccatttt tcgacatcgt cgtcacagac cttccagcga cgcccgatag catgcgtgca
    11101 gaacagtgac cgaccggcat catgcatgac atccccgtgc gcgtcacctc cagcaccgcc
    11161 gccgacagga cgggccaagg cggcatgagg agggcggcag cgcagcgggg atgatgattc
    11221 caaccggcca ccggggaaat ggatgatctc tcacgatgac ggatgagacg gtgacgcatg
    11281 gcaacgctga aagacgtggc gaaggcggcg ggggtatcgc cgagcaccgt gtcgtacacg
    11341 cttcgcggcg gtgcctacgt gtcgcaggag accccggggc agatctgcgc gatcatcgag
    11401 cgcaacaaga acaccacgcc ggtcgacatc ctgcactgac cgcccccttc acccggctcg
    11461 cctcggctcg gctccgccgc cctcccccg
//
