LOCUS       c00162_gnlPro..        13387 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FOBPMGJP_166.
ACCESSION   c00162_gnlPro..
VERSION     c00162_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 02:29:12
            Original ID  :: gnl|Prokka|FOBPMGJP_166
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13387
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13387
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9934:13387](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9935..13387
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13387
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13387
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             2..556
                     /locus_tag="ctg162_1"
                     /transl_table=11
                     /translation="SPAGRAVSAETPAAAPQQTGFNPDGGDVRHDKTFVVFSGDLDKTI
                     AVFIMANGAAAMGRKVTIFFTFWGLNILRKPKRVRVRKTLIERMFGMMMPRGTRKLGLS
                     RMNMGGIGAKMIRWIMKSKNVESLESLMKQATDHGVRLVACQMSMDIMGIHQEELIDGV
                     ELGGVSTFLGSGETSDMSLFV"
     CDS             630..1607
                     /locus_tag="ctg162_2"
                     /transl_table=11
                     /translation="MTRKLILDLDTGIDDTLAIAYALASEQADDVRLIGITGTYGNVTV
                     ETGMRNALAVTDLLGHPEVSVYPGLDRPSTAPENFRYSPSAGTRRIHGDNGIGDMTIPD
                     SRRSPETTAAADFIIDAAHTYGKDLVIVPTGAMTTIAEVCRREPRIGELVGSITFMGGA
                     LTVPGNVTPGAEANIMQDPEAADAILRSGVETTMIGLDVTHQAVLTRRDIERWRRLGTA
                     AGDFLAGMTDFYIDAYSATQPELEGCGMHDPLAVAAALDPTLVTTLGMNLQVDLEGAYR
                     GRTIGDRAHDRLTDSHKTTQVAVRVDIARFKSQFLDRITALASH"
     CDS             complement(1733..1894)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LacI"
                     /gene_functions="regulatory (smcogs) SMCOG1013:Bacterial
                     regulatory proteins, lacI family (Score: 52.5; E-value:
                     1e-16)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg162_3"
                     /sec_met_domain="LacI (E-value: 1.7e-17, bitscore: 52.5,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATLKDVAKAAGVSPSTVSYTLRGGAYVSQETPGQVCAIIERNKN
                     TTPVDILH"
     CDS             2838..3767
                     /locus_tag="ctg162_4"
                     /transl_table=11
                     /translation="MLPEDLQALPYIPVIVSATPWFVILAVLALILSVISRRWIAMLMA
                     LACIGLQVWWQWPFFSASTKLPAAVDAAMASTRADTGDMIARVMTFNVYKGHADAKAIV
                     DIVRDQRVEVLALQETTNDFVKKLDEAGIHSYLPYSQVSSSDGVYGNGIWSATELRRPV
                     DDEVGSSASFMPGGTVTFGGGKAQLRFVSVHTTAPIPGYWSRWKRSLDELASMRSREGS
                     RYVFMGDFNATTDHTPFRNILGNRFSDAARQSGHGFTFTWPSNKLPLPRFAGIDHIVLD
                     KDIIAGQMQVKSVAGSDHAALLATIVVQ"
     CDS             complement(4072..4371)
                     /locus_tag="ctg162_5"
                     /transl_table=11
                     /translation="MTSKNASAASEPATSLTDKEREAIAQMPYEEARDKLIQAVQALEA
                     GGLNLDQSMRQWEIGEALAKRAQSLLNEVKAKLDAAQAEQANSADTAGTQSNLD"
     CDS             complement(4483..5808)
                     /locus_tag="ctg162_6"
                     /transl_table=11
                     /translation="LSFLYVNLEGMNQEQDLAIATQRPSEGGGERIPKPFDQLPRLAAE
                     TTADNPWPVSVLSQKFHTAVERWPAAWIAGQITEINTRRAGSAYLTVRDDVEDIAISVS
                     GWRAFASKAASFKQGDRVVVHGKADIWVKQTRLSFIGDDIRKIGSGGGLKEQIDQLRMK
                     LKGEGLFDADRKLPLPEFPSCIGLICAPHARAEGDVITNVRLRWPTVRFNIVHAFVQGP
                     QCPQSIVEAIHRLDADPDVDVIIVARGGGSFEDLIGFSDEAVVRATAGCETPIVSAIGH
                     EDDWTLIDLAADLRASTPTDAAKKVVPDVHEQWQLIGNAIDRMRMRIDARVGNEIRLVE
                     GYANRPSLTQPLTMLEPYQRFVDDARRRMDIGLTRIVDDASLTVEKLHASLTALSPQST
                     LDRGYAVVQNADGHVIDDAGKVSAGDHLTLTLRKGVITATAQ"
     CDS             6105..8489
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NRDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg162_7"
                     /sec_met_domain="NRDD (E-value: 2e-170, bitscore: 557.6,
                     seeds: 337, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALLMNASTATSSKVLVEKRDGRVVDFDPINIISAVKSAFADLD
                     KQVGPEEEKLIRGFADQIEGEITERYNGPAKIEDIQNLVEHALIDAHLYDVARAYTNYR
                     LDKDIQRAKATDVNEAVSRFINQDPTLIHENANKDANVYATQRDLLAGAVSKAAAFNML
                     PPAVANAHMKGDIHFHDADYSPFTAQSNCSLPNFWDMLANGFTLGNAPMASPKSIAIAA
                     TQITQIMKDVASSQYGGQTANRADEHLAAYAKKDYEKFLEEARETIPDGMPVEFARRQV
                     ENAKANEPAKLHFGSREPLPMDTPFHTDVDELEQEREILAKVRTRKSIYDAMQTMEYQI
                     NSNRVSNGQTPFVTVGFGLGTDWFAREVQRAILLNRIRGLGKDHHTAIFPKLVFTVRHG
                     VNADPGDPNYDLKQLALECATKRMYPDVVFYENIVKITGSFKAPMGCRSFLQGWINPET
                     GKDEEDGRMNLGVVSVNVPRIAIESHGSKERFWKLFNERMEVAHQALQFRIMRCKQATP
                     VNAPTLFRFGAFGRLGASGNVDTLFKNERATVSLGYIGLAEATAVFYGKDWIRDHGWDP
                     QGKEFALSIVKRMSELCKQWSKAEGYHYSVYSTPAESLTDRFNRMDREKFGRIEGVTDH
                     DFYTNSFHYPVWLQPTPMEKLNYEKDFPYFASGGFINYCEYPCLQDNPKALEAVWDYAY
                     NIGIGYLGTNTPIDHCFVCGFQGDFEPTDEGFKCPECGNCDPDKCNVTKRTCGYLGNPV
                     QRPMVHGRHEEISHRVKHMSGETGHVTLADGSEREWFEEAK"
     CDS             8644..9351
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 166;
                     E-value: 1.9e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg162_8"
                     /sec_met_domain="Fer4_12 (E-value: 3.1e-52, bitscore:
                     166.0, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRKSTLHDFAAGETGRGPGVPSSLTNNPRSGQWDGRRMSKRMIA
                     DYKTFIVTDGEGVRNSLYVSGCPFHCVECFNSSIWDFQAGHEYTQKLEDKIVDDLKAPW
                     IQGITFLGGEPMLNTPVLLPLARRIRGEFGHDKDIWCWTGYTWEELMRPGETPDKLELL
                     QLIDILVDGRYLKDQHDSLLQFRGSRNQRILDVPRSLAAGRPVVWAKLHDQERDIPEMY
                     LKDREAGEGAQAS"
     CDS             9439..9699
                     /locus_tag="ctg162_9"
                     /transl_table=11
                     /translation="MALLLPAFIWPCVSPLFHVMMLGFREGCSRMLGTGLGWTTLYMRG
                     VRDGVVDVFAGSGVPGPLEVSDTAAGVWPAVVTIMAAISGI"
     CDS             9935..13387
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg162_10"
                     /sec_met_domain="HGD-D (E-value: 8.9e-21, bitscore: 64.3,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.1e-39, bitscore:
                     125.8, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDTANTAAESHDSKPLRVGLDIGSTTVKAVVLDQTNALNDVLFS
                     DYRRHHANVRATVAGLLKDIHQTLVDLGRGDEPIRLAITGSGGLTLADNLHVPFIQEVI
                     AETRAIDEEYPQADVIIELGGEDAKITYLKPTPEQRMNGSCAGGTGAFIDQMATLLDTD
                     ASGLNDYAKDYKTLYPIASRCGVFAKTDLQPLINDGAAKPDLAASIFTAVATQTIAGLA
                     SGRPIHGTVIFLGGPLFFMSELREAFHRALAGKVDEFIVPTDAHLYVAYGSALIAGEPD
                     GIDVDGVHFEPRTCDDIIAALDDLKNLPANTPTMPPLFSSDQEREAFNERHHREHIHIG
                     TLEGAKGPHFLGIDAGSTTIKATLVNDDREIVWSSYATNEGSPLTAAINIVKKIQSELP
                     EGAWIARSCATGYGEGLITTGLHLDEGVVETMAHYRGAEMVSPGVTAVIDIGGQDMKYL
                     AITDGVIDSIAVNEACSSGCGSFLQTFAQSMGLTIQEFTQAALNSDHPVDLGSRCTVFM
                     NSSVKQAQKEGASMENIAAGLCYSVVRNALYKVIKLRDSGELGDTVVVQGGTFLNDAVL
                     RAFELLTEREVTRPNIAGLMGAFGAALTARMHYEDVADDAHDHDAEVSAGQSADMAGSD
                     DVSAEQDHEVVIDGVHHTASNILSGDDLDNMSMTSERDVCKLCQNHCKLTITTFADGSR
                     YVTGNRCERGGDAKKKRSDRPNLYDYKYKRCFAYRRLTDKKATRGEIGIPRVLNMYENY
                     PFWFTLLTSLGFKVMISGRSSHELFETGIESIASENICYPAKLVHGHIKWLLGKGVKNI
                     FYPCVSYEDNLVPNTDNHYNCPVVANYPVVIGANMPELREDGIRYMHPYFNLANHELMV
                     DRIVEEFAWANVSREEAETAVKAAYAEDKIFKNDVQEEGFKALAYMKEHNCRGIVLAGR
                     PYHIDPEVNHGIPETICALGMVVLSEDSICELQPGENLHLSDYLSEGEEDPRKKNANGF
                     RHVGDRKVTVSRMPLRVTNQWAYHSRLYAAAHFVASYPGLELVQLNSFGCGLDAITTDQ
                     VAEILADKADVYTLLKIDEVSNLGAAKIRLRSLKAAVEAAEKQKNAAEQPAPHSTGFRK
                     TGSEAPTPGRQVMLDTVMKSNPQLTKAVKDASRRAAQAESRLAA"
ORIGIN
        1 gtcgccggcc ggtcgggcgg tatcggccga gactcccgcc gccgcaccgc agcagaccgg
       61 cttcaacccg gatggcggcg acgtccgcca tgacaagacc ttcgtcgtgt tcagcggtga
      121 cctcgacaag accatcgccg tgttcatcat ggcgaacggc gccgccgcga tgggccgcaa
      181 ggtcacgatc ttcttcacgt tctgggggct caacatcctg cgcaagccca agcgcgtgcg
      241 tgtcaggaag acgctcatcg agcgcatgtt cggcatgatg atgccgcgcg gcacgcgcaa
      301 gctcggcctc tcgcgcatga acatgggcgg catcggcgcg aagatgatcc gctggatcat
      361 gaaatccaag aacgtggaat cactcgaatc gctgatgaag caggcgaccg atcacggcgt
      421 gcgcctggtc gcatgccaga tgtcgatgga catcatgggc atccatcagg aggagctcat
      481 cgacggggtg gagctcggcg gcgtctcaac gttcctcggc tccggcgaga ccagcgacat
      541 gagcctgttc gtctgacggg acgcggcgag gccggttgac agtcgccata ggtgtgcggc
      601 gtagaatacg gaaggcgaag gagacccgca tgacacgcaa actcattctc gatttggata
      661 ccggcatcga cgacacactg gcaatcgcgt atgcgctcgc aagcgaacag gccgatgacg
      721 tccggctgat cggcatcacc ggcacctatg gcaacgtcac cgtcgagacc ggcatgcgca
      781 acgcgctcgc cgtcaccgac ctgcttgggc atcccgaagt gtcggtgtat cccggtctcg
      841 accgcccgtc gaccgcaccg gaaaacttcc gctattcgcc gtcggcagga acgcggcgca
      901 tccacggcga caacggcatc ggcgacatga cgatccccga ttcgcggcgc tcgccggaaa
      961 cgacggccgc ggcggatttc atcatcgacg cggcgcacac gtacggcaag gacttggtca
     1021 tcgtgcccac cggcgcgatg accacgatcg ccgaagtctg ccgtcgtgag ccgcgcatcg
     1081 gcgagctcgt cggttccatc acgttcatgg gcggtgcgct gaccgtgccg ggcaatgtga
     1141 cacccggcgc tgaagcgaac atcatgcagg acccggaggc cgccgacgcc atcctgcgca
     1201 gcggcgtgga aaccacgatg atcggccttg acgtcacgca tcaggcggtg ctcacgcggc
     1261 gcgacatcga gcgatggcgg cggctgggca ccgcggcggg tgatttcctg gcgggcatga
     1321 cggatttcta catcgacgcg tattcggcga cgcagcccga gctggagggg tgcggcatgc
     1381 acgatccgct tgccgtggcc gcggcgctcg acccgacgct ggtcaccacg ctgggcatga
     1441 acctgcaggt cgacttggag ggcgcgtatc gcggcaggac catcggcgac cgcgctcacg
     1501 accggctcac cgactcgcac aagaccacgc aggtggccgt gcgcgtcgac atcgcgcgat
     1561 tcaagagcca gttccttgac cggatcacgg cgctggcctc ccactgatcg ccgcgcggcg
     1621 cttgaccatt ccccgccctc ttcccgcgaa agtcccatgt acattggtcg tgatgggact
     1681 ttcgcgggat ggcggcggag ccgagccgag gcgagccggg tgaagggggc ggtcagtgca
     1741 ggatgtcgac cggcgtggtg ttcttgttgc gctcgatgat cgcgcagacc tgccccgggg
     1801 tctcctgcga cacgtaggcg ccgccgcgaa gcgtgtacga cacggtgctc ggcgataccc
     1861 ccgccgcctt cgccacgtct ttcagcgttg ccatgcgtca ccgtctcatc cgtcatcgtg
     1921 agagatcatc catttccccg gtggccggtt ggaatcatca tccccgctgc gctgccgccc
     1981 tcctcatgcc gccttggccc gtcctgtcgg cggcggtgct ggaggtgacg cgcacgggga
     2041 tgtcatgcat gatgccggtc ggtcactgtt ctgcacgcat gctatcgggt gtcactggaa
     2101 ggcctgtgac gacgatgtcg aaaaatggcg ctctcaaaac tcgcagagtg acggcaccct
     2161 tcaaaaccat tggaaaataa gggatttcaa caaccgtcac tgtgcgtgtg cacacgcaca
     2221 gtgacggtac cctcgcacag tgacggtata ttcccgaaat gtctcgtatg gtatggatgc
     2281 gcggggattg ggatccgggc gatagactcg atagttattc aaggatgacc gaatcgttct
     2341 gctcgggtct tccagtcgaa tgggtgcccc ggatgcgatt cgaacgcacg acacccgctt
     2401 taggagagcg gtgctctatc ccctgagcta ccggggcaac gaatgaccat tatacatgtc
     2461 gggcggatat gcgcgtatcg tgcgcagtgt gaagcccgca ggccgccgcg catacgtgcc
     2521 ggaatgggga atgattctcg ggaacgatgg cgtccgcggt tccggggcgt tatcgtatga
     2581 gcttgtatgc gcgacggctg gaagaataca tgtcgttgcg taccggttga cggacgacag
     2641 gggagtggcg aatggcaaac gcgcgaggat catcacggaa cgcctacggc tcagcggctc
     2701 ggcggtccgg cgcgtcgtcc ggcactgcga aaaggcccgc cgcgaaaaca agcgccccac
     2761 gcggccgacg ccaccgtctc cttggcgtct tgtcggtcat attcgccgct ctcgcattgg
     2821 tgtgcagcgt cctgcgcatg ctccccgagg acctgcaggc gctgccgtac atccccgtga
     2881 tcgtatccgc gacgccgtgg ttcgtgattc tcgccgtgct cgcgctgata ctgtcggtca
     2941 tctcgcgccg ctggatcgcc atgctgatgg cgctcgcctg catcggcctc caggtgtggt
     3001 ggcagtggcc gttcttcagc gcgtccacga agctgccggc ggccgtcgac gcggccatgg
     3061 catcgacccg ggcggacacc ggcgacatga tcgcccgcgt gatgaccttc aacgtctaca
     3121 aaggccatgc ggacgcgaag gccatcgtcg acatcgtgcg ggatcagcgc gtcgaagtgc
     3181 tcgcgttgca ggagacgacg aacgatttcg tcaagaagct cgacgaggcg ggcatccaca
     3241 gctatctgcc gtattcgcag gtttcgtcgt cggacggtgt ctacggcaac ggcatctggt
     3301 ccgcgaccga gctcaggcgt ccggtcgatg acgaggtcgg gtcgagcgcg tcgttcatgc
     3361 cgggcggcac cgtgacgttc ggcggcggca aggcccagct gcgattcgtc tccgtgcata
     3421 ccaccgcgcc gattcccggc tactggagcc ggtggaagcg ctcgttggac gagctggcat
     3481 ccatgcgctc gcgcgaaggt tcgcgctacg tgttcatggg cgatttcaac gccacgaccg
     3541 accacacgcc gttccgcaac atcctgggga accggttctc ggacgccgcg cggcagtcgg
     3601 ggcacgggtt cacgttcacc tggccgtcca acaagctgcc gctgccgcgg ttcgccggca
     3661 tcgaccatat cgtgctggac aaggacatca tcgccggtca gatgcaggtc aagtcggtcg
     3721 ccggctcgga tcacgccgcg ctgctcgcca ccatcgtcgt gcagtgacgg cggtgacggc
     3781 cggctgatcg gggcggtacc ttacggcgac gttgtcatgt tgtggtaggc gtcgggtgat
     3841 gacggatgcc gcgtagtgcg actacggtgc gtggcactac ggcggtgcgt caccacgcat
     3901 atggggacat agatggtctc ggcacgccat cgttgcgtcc ataagtgctc gcccaaacga
     3961 cggctgcgcg cacatatggg cgcaaacctc gtgttttccg tccataagtt cgcgcggact
     4021 tcgccgtggc gcgtgcgctt atggacgcaa cgtcccgcgt agggtgcccc gtcagtccag
     4081 gttggattgg gtgccggcgg tgtcggcgct gttggcctgc tcggcctggg cggcgtcgag
     4141 cttggccttg acctcgttca gcaggctctg cgcacgcttg gcaagcgctt cgccgatctc
     4201 ccactggcgc atggactggt cgaggttcaa tccgccggcc tccagcgcct gcacggcctg
     4261 gatgagcttg tcgcgggcct cctcgtacgg catctgcgcg atggcctcgc gctccttgtc
     4321 ggtcaggctg gtcgccggct cgctcgccgc cgatgcgttc ttgctggtca tgatggtctc
     4381 cttctgtcgt gtatgcgtgt cgtattcgat tggataacgg tcatatatat atggttatgc
     4441 ggctgatatc tgccccgcac tctgctgccg tgcggcactc cgctactggg cggtggcggt
     4501 gatgaccccc ttgcgcagcg tcagcgtgag atggtctccc gcgctcacct ttccggcgtc
     4561 gtcgatgacg tgcccgtcgg cgttctggac gacggcgtat ccgcggtcga gcgtggattg
     4621 cgggctgagc gcggtcaggc tggcatgcag cttctccacg gtcaggctgg cgtcgtccac
     4681 gatgcgcgtc aggccgatgt ccatgcggcg gcgcgcgtcg tcgacgaacc gttggtacgg
     4741 ctccagcatg gtcagcggct gcgtcaggct gggccggttc gcgtaccctt cgaccagccg
     4801 tatctcgttg ccgacgcgcg cgtcgatgcg catgcgcatg cggtcgatgg cattgccgat
     4861 cagctgccac tgctcgtgca cgtcgggcac gaccttcttc gccgcgtcgg tcggcgtcga
     4921 ggcccgcagg tccgccgcca ggtcgatcag cgtccagtcg tcctcatgcc cgatggcgga
     4981 gacgatcggc gtctcgcatc ccgccgtggc gcgcaccacc gcctcgtccg agaatccgat
     5041 gaggtcctcg aacgagccgc cgcctcgcgc cacgatgatc acgtcgacgt ccgggtcggc
     5101 gtctagccgg tgaatcgcct cgacgatgga ttgcgggcac tgcggccctt gtacgaaggc
     5161 atggacgatg ttgaaccgca ccgtcggcca gcgcagccgc acgttggtga tgacatcgcc
     5221 ttcggcccgt gcgtgcgggg cgcatatcag tccgatgcag gaggggaatt ccggcagcgg
     5281 cagcttgcgg tccgcgtcga acaggccctc gcccttgagc ttcatgcgca actggtcgat
     5341 ctgctccttc agtccgccgc cggagccgat cttgcggatg tcgtcgccga tgaagctcaa
     5401 ccgcgtctgc ttgacccaga tgtcggcctt gccatgcacg accacgcggt cgccctgctt
     5461 gaatgaggcg gccttcgagg cgaacgcccg ccagccggac acggatatgg cgatgtcttc
     5521 cacgtcatcg cgcaccgtaa gatacgccga gccggcgcgg cgcgtgttga tctccgtgat
     5581 ctgcccggcg atccacgcgg cgggccagcg ctccaccgcg gtatggaatt tctggctcag
     5641 tacgctgacc ggccaggggt tgtccgcggt ggtctcggct gccaggcgcg gcagttggtc
     5701 gaagggcttg gggatgcgct ccccgccgcc ctccgacggc cgctgcgtcg cgattgcaag
     5761 gtcctgttcc tgattcatgc cttcaaggtt tacgtacaga aaggacaagt ttttctgcct
     5821 gcgagagcgt cgccgtcgga cggtatcatt gttggccggc ttttcggtga tggtctcgcc
     5881 gcgacacgct gacgacatac cgtgaagtag atcacacgga tgttcttttc ggctctattt
     5941 cgccgaaatg tgcatatcta ggattgtttt cggcgtttcc ccactatatc taggggtggc
     6001 atgtcgtata gtcatcagag aacaaacaac ttacacacgt gtgatttcgg ctcggcgacc
     6061 gccgcaagac atgccgggaa tcacgaaagg acagggatta ggacatggat gctctgctga
     6121 tgaacgccag taccgccacc tcctccaagg tgctggtgga gaagcgtgac ggtcgcgtcg
     6181 tcgacttcga cccgataaac atcatcagcg ccgtgaagtc cgccttcgcc gaccttgaca
     6241 agcaggtcgg cccggaggag gagaagctga tccgcggctt cgccgaccag atcgaaggcg
     6301 agatcacgga gcgctacaac ggccccgcca agatcgagga catccagaac ctcgtcgagc
     6361 acgccctgat cgacgcccac ctgtacgacg tggcccgcgc ctacaccaac taccgtctcg
     6421 acaaggacat ccagcgcgcc aaggccacgg acgtcaacga ggccgtctcc cgcttcatca
     6481 accaggatcc gacgctgatc cacgagaacg cgaacaagga tgccaacgtc tacgccactc
     6541 agcgcgacct gctcgccggc gccgtctcca aggccgccgc gttcaacatg ctgcccccgg
     6601 ccgtcgcgaa cgcgcacatg aagggcgaca tccacttcca cgacgccgac tactcgccgt
     6661 tcaccgcgca gtccaactgc tcgctgccca acttctggga catgctcgcc aacggcttca
     6721 cgctcggcaa cgcgccgatg gcctccccga agtccatcgc catcgccgcc acgcagatca
     6781 cccagatcat gaaggacgtg gcctccagcc agtacggcgg ccagaccgcc aaccgtgccg
     6841 acgagcacct cgccgcctac gcgaagaagg actacgagaa gttcctcgaa gaggcccgcg
     6901 agaccatccc cgacggcatg ccggtggagt tcgcccgtcg tcaggtcgag aacgccaagg
     6961 ccaacgagcc cgccaagctg cacttcggct cccgcgagcc gctgcccatg gacacgccgt
     7021 tccacaccga cgtcgacgag ctggagcagg agcgtgagat cctcgccaag gtccgcacgc
     7081 gcaagtccat ctacgacgcc atgcaaacga tggagtacca gatcaactcc aaccgcgtct
     7141 ccaacggcca gaccccgttc gtcaccgtcg gcttcggcct gggcaccgac tggttcgccc
     7201 gcgaggtgca gcgcgcgatc ctgctcaacc gcatccgcgg cctcggcaag gatcaccaca
     7261 ccgcaatctt cccgaagctc gtgttcaccg tgcgccacgg cgtgaacgcc gaccccggcg
     7321 acccgaacta cgacctgaag cagctcgccc tggaatgcgc caccaagcgc atgtacccgg
     7381 acgtcgtgtt ctacgagaac atcgtcaaga tcaccggctc cttcaaggcg ccgatgggct
     7441 gccgctcctt cctgcagggc tggatcaacc ccgagaccgg caaggacgag gaggatggcc
     7501 gcatgaacct cggcgtcgtt tccgtgaacg tgccgcgcat cgccatcgaa tcccacggca
     7561 gcaaggagcg cttctggaag ctgttcaacg agcgcatgga ggtcgcccac caggcgctgc
     7621 agttccgcat catgcgctgc aagcaggcca ccccggtcaa cgcgcccacc ctgttccgct
     7681 tcggcgcctt cggtcgcctc ggcgcgagcg gcaacgtcga cacgctgttc aagaacgagc
     7741 gcgccaccgt gtcgctcggc tacatcggcc tggccgaggc caccgccgtc ttctacggca
     7801 aggactggat ccgcgaccac ggctgggacc cacagggcaa ggagttcgcg ctgtcgatcg
     7861 tcaagcgcat gagcgaactg tgcaagcagt ggagcaaggc cgaaggctac cattactccg
     7921 tgtactccac accggccgaa tccctcaccg accgcttcaa ccgcatggac cgcgagaagt
     7981 tcggccgcat cgagggcgtc accgaccacg acttctacac caactccttc cactacccgg
     8041 tgtggctgca gcccaccccg atggagaagc tcaactacga gaaggacttc ccatacttcg
     8101 cgtccggcgg cttcatcaac tactgcgagt acccgtgcct gcaggacaac ccgaaggcgc
     8161 tggaggccgt gtgggattac gcctacaaca tcggcatcgg ctacctcggc acaaacacgc
     8221 cgatcgacca ctgcttcgtg tgcggcttcc agggcgactt cgagccgacc gacgagggct
     8281 tcaagtgccc tgaatgcggc aactgcgacc ctgacaagtg caacgtcacc aagcgcacct
     8341 gcggctacct cggcaacccg gtgcagcgcc cgatggtgca tggccgtcac gaggagatct
     8401 cccaccgcgt caagcacatg agcggcgaga ccggtcacgt gacgctggcg gacggctccg
     8461 agcgcgagtg gttcgaagag gccaagtaac tgccggtacc gcgcgttgtg ctgtccgcga
     8521 gggtcgccgg tatatgttgt ctgacacact caaggccgtt cggccaagct tacggtcaga
     8581 caacatatac cggcgaccct cgcccgttgc gcgcaacgtt acggttggac agggaggatg
     8641 atgatggaca ggaagtcgac gctgcatgat ttcgcggccg gcgagaccgg ccgcggaccc
     8701 ggagtgccgt catcactgac caacaacccc cgttccggcc agtgggacgg gcggcgcatg
     8761 tccaagcgca tgatcgccga ctacaagacc ttcatcgtca ccgacggcga aggcgtacgc
     8821 aattcgctgt acgtctccgg ctgcccgttc cactgcgtcg aatgcttcaa ctcgtcgatc
     8881 tgggatttcc aggccggcca cgaatacacg cagaagctcg aagacaagat cgtcgacgac
     8941 ctcaaggcgc cgtggatcca gggcatcacg ttcctcggcg gcgaacccat gctgaatacg
     9001 cccgtcctgt tgccgctcgc ccggcgcatc cgcggcgagt tcggccacga caaagacatc
     9061 tggtgctgga ccggctacac gtgggaggag ctgatgcgtc ccggtgagac gccggacaag
     9121 ctcgaactgt tgcagctcat cgacatcctc gtcgacggcc gctacctcaa ggaccagcac
     9181 gactccctcc tgcagttccg cggatccaga aaccagcgca tcctcgacgt gccgcgttcg
     9241 ctggccgccg gcaggcctgt cgtctgggcc aagctccacg accaggagcg cgacatcccc
     9301 gaaatgtacc tcaaggatcg cgaggccggc gagggcgcac aggcatcgtg acggcgccgc
     9361 cggccttgcc atccatccag tggattcgat gccgtcggcc tgatcgcggc catcctgaca
     9421 gtctcgcccg ccatcggcat ggccttgctt ctccccgcat tcatctggcc ttgcgtgagt
     9481 ccgctgttcc atgtgatgat gctcggtttc cgggaagggt gctcgcgcat gctgggcacc
     9541 ggattggggt ggacgactct gtatatgcgc ggcgtgcggg acggcgtggt cgacgttttc
     9601 gcgggcagcg gcgtgcccgg tccgctggag gtctcggata ctgcggccgg ggtatggccc
     9661 gccgtcgtca ccatcatggc cgccatatca gggatttgag cgggactggg ggcaatagca
     9721 ctagtccata agaccaccag cctgctggca tgctcggctc accccccgaa tgcgcgataa
     9781 tggggggtaa cgccgcaatc gtggggaaac cgtcgagttt ccgttttgcg tttgttagcg
     9841 aaatcacgcc atacgacggc tcgttaggag gggtctcgga ctacattaca taaggaagta
     9901 gcgggaagtc ccgaaacgaa gacagaggta acagatggtg gatacagcga ataccgcggc
     9961 cgaaagccac gatagtaagc cgttgcgcgt gggtctggat atcggatcga ccacggtcaa
    10021 ggccgtggtg ctcgatcaga ccaatgcgct caatgacgtg ctgttctccg actaccgacg
    10081 tcaccacgcc aacgtccgcg ccacggtggc tggactgctc aaggacatcc atcagacgct
    10141 cgtcgacctc ggccgcggcg acgagcccat tcgtctcgcc atcaccgggt ccggcggcct
    10201 gacgctcgcc gacaacctgc acgtgccgtt catccaggag gtcatcgccg agacccgcgc
    10261 gatcgacgag gaatacccgc aggccgacgt catcatcgag ctcggcggcg aggacgccaa
    10321 gatcacgtac ctgaagccca ctcccgaaca gcgcatgaac ggttcgtgcg cgggcggcac
    10381 cggcgcattc atcgaccaga tggccacgct gctcgacacc gacgcctccg gcctcaacga
    10441 ttacgccaag gactacaaga ccctgtaccc gatcgcgtcg cgttgcggcg tgttcgcgaa
    10501 gaccgacctg cagccgctga tcaacgacgg cgccgccaag cccgatctgg ccgcgtcgat
    10561 cttcaccgcg gtggccacgc agaccatcgc cggcctggct tccggacgcc cgatccacgg
    10621 cacggtcatc ttcctcggcg gcccgctgtt cttcatgtcc gagctgcgcg aggcgttcca
    10681 ccgcgcgctc gccggcaagg tcgacgagtt catcgtgccg accgacgccc acctgtacgt
    10741 cgcatacggc tccgcgctga tcgctgggga gccggatggc atcgacgtcg acggcgtgca
    10801 tttcgagccg cgcacctgtg acgacatcat cgccgccctc gacgacctga agaacctgcc
    10861 ggcgaacacg ccgaccatgc ccccgctgtt ctcctccgac caggagcgcg aggcgttcaa
    10921 cgagcgccac catcgcgaac acatccacat cggcacgctc gaaggcgcga aaggcccgca
    10981 cttcctcggt atcgacgcgg gttcgaccac catcaaggcg acgctcgtca acgacgaccg
    11041 cgagatcgta tggtccagct acgccaccaa cgaaggcagc ccgttgaccg ccgccatcaa
    11101 catcgtcaag aagatccagt ccgagctgcc cgaaggcgcg tggatcgccc gatcctgcgc
    11161 gaccggctac ggcgagggac tgatcaccac cggcttgcat ctggacgagg gcgtggtcga
    11221 gaccatggcg cactaccgcg gcgccgaaat ggtcagcccc ggcgtcaccg ctgtcatcga
    11281 catcggtggc caggacatga aatacctggc catcaccgac ggcgtcatcg actcgatcgc
    11341 cgtcaacgag gcgtgctcgt ccggttgcgg ctcgttcctg cagaccttcg cgcagtcgat
    11401 gggtctgacc attcaggagt tcacccaagc ggccctcaac tccgaccatc cggtcgacct
    11461 cggctcgcgc tgcacggtgt tcatgaactc gtccgtcaag caggcacaga aggaaggcgc
    11521 gtcgatggag aacatcgccg ccggcctgtg ctattcggtc gtgcgcaacg cgctgtacaa
    11581 ggtcatcaag ctgcgtgact ccggtgagct cggcgacacc gtcgtcgtgc agggcggcac
    11641 gttcctcaat gacgccgtgc tgcgcgcctt cgagctgctc accgagcgcg aggtgacccg
    11701 cccgaacatc gccggcttga tgggtgcatt cggcgccgcc ctgaccgcac gcatgcatta
    11761 cgaggacgtg gccgacgacg cgcacgacca cgacgccgaa gtctccgcgg gccagtccgc
    11821 cgatatggcc ggcagcgacg atgtcagcgc ggagcaagac cacgaggtcg tcatcgacgg
    11881 cgtgcaccac acggcgtcca acatcctgtc cggcgacgac ctcgacaaca tgtcgatgac
    11941 ctccgagcgc gacgtgtgca agctgtgcca gaaccactgc aagctcacca tcaccacgtt
    12001 cgccgacggc tcgcgctacg ttaccggcaa ccgctgcgag cgcggcggcg acgcgaagaa
    12061 gaagcgctcc gacaggccga acctgtacga ctacaagtac aagcgctgct tcgcctaccg
    12121 caggctcacc gacaagaagg ccacccgcgg cgagatcggc atccctcgcg tgctcaacat
    12181 gtacgagaac tacccgttct ggttcacgct gctcacctcg ctcggcttca aggtgatgat
    12241 ctccggccgc agctcgcacg agctgttcga gaccggcatc gaatcgatcg cctccgagaa
    12301 catctgctac ccggccaagc tggtgcacgg ccacatcaag tggctgctgg gcaagggcgt
    12361 caagaacatc ttctacccgt gcgtgagcta cgaggacaac ctcgtgccca acacggacaa
    12421 ccactacaac tgcccggtcg tggccaacta cccggtggtg atcggcgcga acatgcccga
    12481 actgcgcgag gacggcatcc gctacatgca cccgtacttc aacctcgcca accacgagct
    12541 catggtcgac cgcatcgtcg aggagttcgc gtgggcgaac gtgagccgcg aggaggccga
    12601 gaccgcggtc aaggccgcgt acgccgagga caagatcttc aagaacgacg tgcaggagga
    12661 aggtttcaag gcgctcgcct acatgaagga gcacaactgc cggggcatcg tgctcgccgg
    12721 gcgcccgtac cacatcgacc ccgaggtcaa ccacggcatc cccgagacga tctgcgcgct
    12781 cggcatggtc gtgctctcgg aggattcgat ctgcgaactg cagccggggg agaacctgca
    12841 tctgagcgac tacctgtcgg aaggcgagga ggacccgcgc aagaagaacg cgaacggctt
    12901 ccgccacgtc ggcgaccgca aggtgaccgt ctcccgcatg ccgctgcgcg tcaccaacca
    12961 gtgggcctac cattcgcggc tctacgcggc ggcgcatttc gtggcgtcct acccgggtct
    13021 cgaactcgtg cagctcaact ccttcggctg cggcctggac gccatcacca ccgatcaggt
    13081 ggccgagatc ctcgccgaca aggccgacgt gtacacgctg ctcaagatcg atgaggtgag
    13141 caacctcgga gcggcgaaga tccgcctgcg ttcgctcaag gccgccgtcg aggccgcgga
    13201 gaagcagaag aacgccgccg agcagccggc cccgcattcc acgggcttcc gcaagaccgg
    13261 atccgaggcg cccacgcccg gccgtcaggt catgctcgac acggtgatga agagcaaccc
    13321 gcagctcacc aaggccgtca aggacgcctc ccgccgcgcg gcgcaggccg agtcgcggct
    13381 cgccgcc
//
