LOCUS       c00035_gnlPro..        16861 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGBEKEKM_37.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 02:19:49
            Original ID  :: gnl|Prokka|AGBEKEKM_37
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16861
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16861
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3616:6861]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3617..6861
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16861
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16861
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..410)
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="VSTQNYSKLIHTMLPALPDYIQDYYQSQKAIPIADSTLYQYLHFY
                     QEFLNWLINSSVTAASSPQTVPLTVLEHLSLRDAQAFMAYLLERPSKTHHNKRMTRRSV
                     ALRLVGIKALYRFLTEESEPHADGEPYFYRNV"
     CDS             complement(1562..2494)
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVFDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAESVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELISAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSTFEG"
     CDS             complement(2524..3492)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg35_3"
                     /sec_met_domain="LysR_substrate (E-value: 2.1e-27,
                     bitscore: 85.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 7.2e-20, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWATYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             complement(3617..4468)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_4"
                     /sec_met_domain="Radical_SAM (E-value: 3.7e-26, bitscore:
                     82.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             complement(4600..6861)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="Gly_radical (E-value: 5.5e-42, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.4e-244, bitscore:
                     802.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDETKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTHNQGVFDAYTPDMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLTGDGEMTDDVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMHDKYYYEAAQLALKDTQLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADNDDYPRYGNNDDRADDIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFEEM
                     "
     CDS             complement(7113..9557)
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVIAAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDRFGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNMVAIADMQPKL
                     LGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQVIAAIRASKDK
                     GDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIAEYQDILARPA
                     ARDRVIEGELKRIAKEYGDDRRSSIQAKIETLEVATTVTVADETVMVQVSRDGYVKRSS
                     LRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGE
                     HLSQTVGLGTDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTYKSKPMMA
                     MKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATGVKSMDLKPDD
                     EVVNFILVKDPTMAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAM
                     MSVDDATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTDVLGKPVFVQTKEEPADQ
                     VE"
     CDS             complement(9564..11576)
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MDKATQAYNDSSIQVLHGLEAVRKRPGMYIGSTDGRGLHHLVYEI
                     VDNSVDEALAGFGDEINVTIHADNSVTVQDHGRGMPTGMHPSGKPTIEVILTVLHAGGK
                     FNQNSYKTSGGLHGVGSSVVNALSESLTVRVVRDKHAFEEHFINGGHPDGSLQKLGKVN
                     EPNGTTITFKPDPTIFQTTVFSYDTLAERLRESAFLLKNITINLTDERTGKHDSYHYPD
                     GLVSFVKYLNEGKDALSQVINFEGKKDGIVVDFAGQYNDGYSENLISFVNNVRTGDGGT
                     HEIGLRSGMTRAFNEFARKVGLLKERDKNLEGSDVREGFAGILSVRIPEEILQFEGQTK
                     GKLGTPQARTVVDGIVYDKLSTFLMENGEESQELVRKAVKARDAREAARKARDDSRTGR
                     KRKKDQGLLSGKLTPAQTKNPKRNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNT
                     QKAKLQDIVKNEEINTMIYTIGAGVGADFDLQQANYDKIIIMTDADTDGAHIQILLLTF
                     FYRYMRPLIDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKGYTLTRF
                     KGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGDRVEPRREWIEHNVKF
                     DMDDDGSILETPTANHEKLQFGAKQIVKQLDKKGK"
     CDS             12010..12717
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MYVRFILLTYHSKVKNAKIVSSLRGGAHLILVLCFILAYFIGAIP
                     FGVVIGKLFYHTDIRKGGSHNIGTTNAYRMLGPVGGSIVLVLDILKGTLAASLPILFGI
                     EHHWLVLIVGLAAVFGHTFSIYIRFKGGKAVATSAGILLAYNPPFFVIAFAIWFSLILL
                     TSMVSVASTLGMVLITAWSLVYHDWLLTTVACGLLVVFLIKHRANFKRIKAGDENMVPF
                     GLGQYLRQHRGRS"
     CDS             complement(12799..13677)
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MVTIANDFLTVKISRHGAELTSIKDNLTGRERLWQADPAVWGRHA
                     PVLFPIVGALADNQYHYAGKTYHMGQHGFARDRDFTVLSATPFKASFVLKDDDKTRAMY
                     PFAFRLIITFALENNNLHVTYHVDNPDKSEPLFFSIGGHPGFKVPMTPDTQFSDYYLNF
                     KPRKSLVQIPLVAGEGIDYTHRTLAATDANLALTHETFDHDALIFALLGKTTFNLVSDK
                     TKHGVSVTMTDTPYLGVWSPYPTTGDFVCIEPWWGIADTIGSTGDLTRKLGINRLEPGT
                     AFEKGYMISIF"
     CDS             complement(13713..15122)
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="MAEVQTPKQIVEKLDQYVIGQDDAKRAVAVALYNRYRRMQLSPKM
                     QEEITPKNLLMIGPTGVGKTEIARRLAKIVEAPFVKVEATKFTEVGYVGRDVESMVRDL
                     AETAVAMEEEKQFSKVRIRAEKEANKRLVKILVPAIRKEKNTNPMAEMMSMLQGMQNGK
                     MPAGDDADAGGEVTDDIRNKRLSVAEQLEKGLLEDHEITVAVNDEKKGGGMGDMYGQMG
                     IDLSDTIGALMPKKKVERTMTVKEAREIFIKEESDKLVNHADIYHDAIQSAENNGIIFI
                     DEIDKIAAGNKHNSGEVSREGVQRDILPIVEGSQINTKYGPINTDHILFIGSGAFAEAK
                     PSDLIAELQGRFPIRVELKDLTEKDFVRILTEPDNALIKQYIALIGADGVKITFTKEAV
                     DRIAEIATQVNHDTDNIGARRLATILEKLLEDVLYEGPDMAMGAVTVTQQYVDDKIGHI
                     AADSNMTRYIL"
     CDS             complement(15166..15690)
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVV
                     IGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHD
                     LLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDI
                     FTNHNVIVESF"
     CDS             complement(15938..16834)
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MKPIAAFQEYLEVERQYSPETVTAYLSDLQEFQAFLKANGGFTDF
                     RHVDDLDVQTYLTDLNKQDLARTSIARKISSLRSFYRYLTRIDVVKRNPFELVELKKQH
                     HHLPQFFYEAEIQELFKSVAGKTPLDQRNRALLEVLYGTGIRVSECAKLTLNQVDFNTA
                     LLLIHGKGNKDRYVPFGQYAQQALRTYLKDGRQVLMAKSQAQHRYVFVNQYGRPITSRG
                     IEYILDQLIKQTTLTANIHPHMLRHSFATHMLDHGADLRTVQELLGHASLSTTQIYTHV
                     TMAHLKNEYMKYYPKHN"
ORIGIN
        1 cagacattcc gatagaaata aggctcgcca tctgcatggg gttcactttc ctccgttaaa
       61 aaccgataaa gcgccttgat cccgactaag cgcaaagcga cactgcgacg cgtcattcgc
      121 ttgttgtggt gcgtcttgga aggccgttca agcaaatacg ccataaatgc ctgggcatca
      181 cgcaacgaca aatgttctaa cacggtcagc gggacggttt gcggtgagga agcggccgtc
      241 acactactgt taatcagcca gttcagaaac tcttgataaa aatgtaaata ctgatacagc
      301 gtcgaatcgg cgatcgggat cgctttttga ctctgataat agtcctgaat gtaatccggc
      361 agggcaggta gcattgtatg aattaatttc gaataatttt gtgtcgacac agatttcacc
      421 tcgaacgtat gttttctttt agataatgtt agtatacgcg aaaacaactg tccttggcga
      481 gggctagtgt tgatgaaaaa tgaacggtgg tgctggttca gccattgttc tgccatgtga
      541 agcagaattg aataaagttt tagctttatc caaaggtgag caaagatgtc agcaaacgcc
      601 tgttggtcag acaaatttta gctggcataa ttctggcatg aattcggcta ttaaatgagt
      661 tcacttcggt caatcattca gcaaacttat tttggccatt ggtcaacaaa ataaatttgc
      721 tgaatgttac gtgaccctca attgttgttg agtcaatttc aaactacaca actcaaaaca
      781 actcaaaaaa tcatcaagca actcgaagcc ggctaactga cgagaatctc acaacatcat
      841 gaagcttgaa ttgatatgca tttttctggt tttggctagc atgacatttt caatcaaaca
      901 aatgcatgca actcagcgta aacgcaaaga tccaattcat aattgactgc cttggtaaaa
      961 aatgcaatcg ccaccaccaa cattacgtcc ggaccacaaa tttttgacag ccatctgaaa
     1021 gaggggacac ccagattcgc agatcaagtg ccaaagccaa ttatttatat tctagtttac
     1081 ataatatata ttatgcgaag cagcgtttga agagacggca tcgtgccatt ctcgcaatat
     1141 ttacgttggc gattatttga ttcgcaattt catacagcac ccgatagtcg cctcattttt
     1201 tgaaccgctg cttgcagcca agtctttaaa agcttctaca atcattggat attttttgct
     1261 tgagtttttt tcgttaagtc acttgcgacg aacaacttat caagttgaat tcccgaactc
     1321 gtctcagaat gcgtctctca gcatgcctca aaatcatcca aaatgaccca tgacaacttg
     1381 ctgttgattc gacccgcgaa ttgctacaca aattttaaat tcacgcatca cgaactgcta
     1441 gccagcttta tatttaacag atttcgcaaa aagatggcta gagacttttt gcaaacaaaa
     1501 aagccgcaac cggctagctg cgactttcct taaaacaatt gtgtgcaatt aaagatgaaa
     1561 gttaaccttc aaacgtgctc tgcattggcg gaacgacctg ctttttgcgg gaaacaaccc
     1621 caggcaatgc caaacgcgcg tccttgtcga actgttcgtt gaaagcactg gcgattttat
     1681 cgcggtcagc accgactgcg aaaccagttg aattgctgtc caagatgtca gtggcaatca
     1741 gcaggaaatc gtcgtagcct ttcgcctgcg cctctttggt catggcactg atcaattcgt
     1801 cctgacgtgc gtaaatgtcg ttcagatcga cagtattgac ctgtccgatg cgaatagact
     1861 tgccgcccat ggtgaaactc ttagcatcgc cttcgataat gtccatatct gacttggcgg
     1921 ccaaattagt acctgccttc agcatggcaa gaccatatga ctgcaaatca attccggcaa
     1981 tcttcgccat ttctggcaaa atcttcttat ccttatcggt tgcggtcggc gacttcaaca
     2041 acagcgtgtc tgaaatcaaa ccagaagcca tcaaaccagc caatgttggc gaaatcttga
     2101 agccatattc ttggaacatc tcaaaaatga cggtattggt gctgccaacc gattctgctc
     2161 ggtaaaacag cggcgctgcc gtgtggaagt tagcgatgcg atgatggtcg acaacagaat
     2221 caatcgtcac gtcttcgata tcactgacac tttgttgaaa ttcgttgtga tcaaccaaca
     2281 tgacatgatc tgtctcgttg gctgccgtct tgataacccg cggtgcctga accttgaagt
     2341 gatcaaagac gaacttagtc tcatcgttcg gttcgcctaa tgctaccgct tcaacatccg
     2401 tgttgcctgc ctgtttctga aattctgccc agctcatggc actcgtaatc gcgtcggtgt
     2461 ccgggttctg atgcccaaaa atcaaagtcg tcatcttatc tgatcgctcc tcaactgaat
     2521 agtttactta tcaagtttaa cacggttttc actgacccgc gacaagtaat ctttttcctt
     2581 cagataatcg tcaaaggtct ggaagaagtt cgagatccgc ggaatgtcag ctttctcttt
     2641 gcgataaaca aaagaaatct caaagcgaat ggccggatca aacgcaatag cataggcctt
     2701 gatttgatca gcgcgtgccc gaacaaaact ggttggtaag gccgtgttga cccctgacaa
     2761 gttaacgaat tgggttaact gatatggcgt ggtgaaatgt gcgaccacgt gcgggaaatc
     2821 aaccatttga ttcttgtacg cctcacgcag aagctgtcca aggaaatagt cgtcaggata
     2881 agttgcccaa ggttcagcta aagtatcttt gaaatggatt cgcttacggt tagccaatgc
     2941 gtcatcgtgg tgcaagaaca gcaattgttc atcaataatt ttcttgctgg cgtatggttt
     3001 ccagttctta atggtctcat ctggcagatt catgatagcc aaatcaatct ggttgttttc
     3061 caaggattcc caaatttcgt gacgggtcat catccgtagc gtcacttcaa cttcaggatt
     3121 cagttgatag taatgagcaa tgaacgcaat aaaggcgcta tcctcgattg agcttaataa
     3181 cccaatattg atttttccga cggttgcact ggttgtttgt tgaatttcgt cggttgtctg
     3241 gttcaagatc tcgtagatct catgggttga ctttaacatg gtctgaccag cgtcagataa
     3301 atgcagtttc ttcccgacag aataaaacag cggtgccccc accgtccgtt ccaatttctt
     3361 gatctgctgt gttaaggctg gctgggtaat gccaagcaat tgggcggctt gggtgtagtt
     3421 catggtttct gccaattgca gaaaatatgt tagtgtcttt gaggaaaaaa tgcgctcttg
     3481 tttcgttttc atagggcggc ttccctttcg tttataattt aataatatcg ttcaaccatc
     3541 atcataagtg gcaatgaaaa aaaacgcaac gaatttgccg cgtttttaat cgttacgtta
     3601 agttctagct aaaaattcag ttgctcgcaa ctggtttcgg acgccagctt tgccatccgg
     3661 tataatcctt aacgtgcagc agattctctg cattcttaac gcgatcggca gacggcggtt
     3721 cgatgccttc aagcgggtac gtaatgccaa gctcgtgata ctttttaacg cctaatgtgt
     3781 gatacggcag aatctcaact ttttggacca catttttgtc caatgtcgca atataatccc
     3841 ctaaccgttt gagataaggg tcaaagtcag tgcgttccgg gaccagaacg tggcgaatcc
     3901 acatgtcatc accatgcgcc gacatatact gcaccatatc caaaatattt tcattaggaa
     3961 aaccggtgag ctttttatgc tcggccgaat caatgtgttt aatatcaact aatgagatgt
     4021 cagtaacagc catcagcttt tcaaactggc caaaccacgg ttggtcacgc gtgaaggggc
     4081 cgcctgacgt atcgaggcaa gtcgaaattc ccagtgcctt agccttggtg aagagttcga
     4141 gaatgaaatc gatttgtacc aaactctcac cgccactgca ggtaataccc ccttggtcac
     4201 cccagaatgc tttatagcgc tgggcatccg ccaaaatttg atcggccgtc atttcttcac
     4261 caaccccaat gttccaggtg tcagggttgt gacaatactg gcaacgcatg cgacaccctt
     4321 gcataaagac aacgaagcga ataccagggc catcgaccga accaaaactt tcgaccgagt
     4381 gaacataccc tttgatcggg ccatcatgat cctgaccaac ttgttctaag atatttaatg
     4441 ggctttgtga ctgatcgatg agtttcatct tattgcctcc actacaacat catgtgtcgt
     4501 tttcaattga ttttcatttc attctgccaa aaaacggcaa cagcatcgtt gccgtctttt
     4561 ggcaaaacag gaatggcttc ctgtcttgag ttaagctgct tacatttctt cgaagaaggt
     4621 ccgagcaatg acatcgtctt gttgttcctt ggtcaaatct gcgaagtaga cgcagtagcc
     4681 agaaacccga acggtcaatg ttgggtattc ttctgggtgc ttctgagcat caatcagggt
     4741 ctccttgttg aagacgttga tgttcaaatg catgccgctg ttttccatat agccgtcaac
     4801 catgtgaacc aaggtatcct tacgagtttc atcatcgtgg cccagtgtgt tcggagtaac
     4861 cccaaacgta ttactaatgc cgtcagttgc gtaatgatac ggaatcttgg cggtggacat
     4921 caaggatgcc aatgcgccgt tcttttctgc gccgtatgcc gggttggcac ctggtgagaa
     4981 tggttcgcct ttttgacgac cgtttggtgt tgtccctgta ttcttaccat aaaccacgtt
     5041 ggaggtaatg gtcaggacac tggtactcaa cttcgcgccg cgatacagat gatgcgtgtt
     5101 catcttgtta tagaaggtct taaccaacca cttagcgatg tcatcagcgc gatcatcgtt
     5161 gttaccataa cgtggatagt catcattgtc agcaacgaag tcaactgcaa caccgttttc
     5221 atcgcgaatt gccttgacat gaccatactt gattgcactg atggaatcaa ccgcgtgtga
     5281 caggccggaa atcccggttg cgaaggtccg gttcagttgg gtatccttca atgccagctg
     5341 tgcagcttca taataatact tgtcatgcat atagtgaatc acattcaaag cattgacata
     5401 cgtgtcggcc agccagtcca tcatcttgtc gaacttattc atgaattctt tgtaatcaat
     5461 gtaatcgctg gtgatcggtg catattcagg ccctacttgc gcttcctgaa tttcatcttt
     5521 cccaccgttg atcgcataca gaactgtctt agctaagtta gcacgggcac caaagtattg
     5581 aacgccatcg gcaattggtt gtgccgagac acagcaagca ataccgtagt aatcggtacc
     5641 ccattcgttg cgcatcaggt catcattttc atattgaatg gttgaacttt ggatggatac
     5701 ttcggttgca tagcgtttga agccttctgg caagcgttcg ctccaaagca aggtgatgtt
     5761 tggttctggt gctgcgccca tgttgtccaa agtcttcagg aaacggaaag ccgtcttggt
     5821 aacgtggtga cggccatcat tgcccattcc tgccaatgac aaggttgccc agattggatc
     5881 gcctgagaac agtgagttat attcttcagt ccggatgaaa cgaaccatcc gcaatttcat
     5941 aaccaaatga tcaatcagtt cctgtgcttg ttcttcgttc aatttgccta agcgcatatc
     6001 gcgttggata taagcatcaa taaccgtatc gatccggcca acggacattg cggcaccgtt
     6061 ttgagtctta acagcagcca gatagccaaa gtagatccac tgaacagctt cttgcgcatt
     6121 agctgctgga cgcgagatgt catagccata ttccttggcc atcttcttca tgtcgtttaa
     6181 ggcacgatat tgttcattga tttcttcacg cagtttgatc acatcgtcag tcatttcgcc
     6241 gtcgccagtc aagttataat ccttgaactt ctcggccatc aaacgatcga tcccgtaaac
     6301 agcgatccgt gggaaatcag aaacaatccg gccacgacca tatgcgtctg gcaagccagt
     6361 cacgatcttg taatggcgag cctttcgcat atcaggggta taagcatcaa agacaccttg
     6421 gttatgggtc ttacgatatt cattgaaaat cttgtgttct tgaggatctg tcttgaagcc
     6481 ataagattcc aatgcatctt cagccattcg aataccgcca aatggcatga atgctcgttt
     6541 gaatggcttg tcggtctgaa caccaacaat cttttcaaga tctttgttca aataaccagg
     6601 gccgtgtgag gtgatcgtag atggaatatt gttgtcagca tccaaaacac cgccatttgc
     6661 acgttcttgc ttctttaaat ttagaacctg attgttcagg actgttgtcg cttcagtggg
     6721 gccagcaagg aaactttcgt ccccgtcata ttggttcagg ttatgctcga taaaatcgcg
     6781 cacattaatt tcttcttgcc agtcgccgcc gttaaagcct tcccaataat taggaacttt
     6841 ggtttcgtca agctgtttca tagttgtttg cctcctaaag tggattacag atgtgacagt
     6901 tcttacaaac acagtataac acgccgccaa atctatgcaa gcgttttatt gcccatataa
     6961 taggcgttat attgtttttt aagtgtgctt cgtcgcttct tttcgcccac gatttcgtca
     7021 ttttgctaaa ttgcgcacaa ctgatctgtc ctataataat caaaaacgcc accatctgta
     7081 ttagtacaga tggtggcgtc aatgatcacc atttattcga cttgatctgc tggttcttct
     7141 ttggtttgaa caaaaactgg cttgccaagg acatcagtgt caatgacaaa cgaaccattc
     7201 gaatagcggt cacctgctgg atgttgtgcc ggattaaggg tcgttacctt acccgtatcg
     7261 gtcaaaacat taaggcgggt agcgtcatcg actgacatca tcgcgacaat ccgatgcgga
     7321 tcacgcttaa gctcacgcaa gaccagtaaa ccacgacggg cacgactcat ttccccgacc
     7381 tcgcttaagg ccatcttttt gaaggcgcca cgttgggtca aaataccgac cttagccata
     7441 gttggatcct tcactagaat gaaattgaca acctcatcgt ctggctttag atccatactt
     7501 ttaacgccgg ttgcccgggc accgacagtt gacacatcgc ttaacgggaa tgtcagtccg
     7561 taagcgtggc ggctgactac aaagacatcc tgttgctgat cagtcgtgaa gtatgcattg
     7621 gtgacaatcg cggctgggtc tttcagcttc atcgccatca tcggcttact cttgtacgtc
     7681 cgttgcggct gcaaatcact taaggcagtt tgtttgatgt acccgtcact tgaccctaac
     7741 acaaaactgc cagcgccatc gagttgatca aaagcaaaca ctgccaagac tttttcgtca
     7801 gtgccaaggc caactgtttg gcttaagtgt tcgccggtgt ctttccaacg cgcatcacta
     7861 atttcatgca ctggtcgata aatgacattt ccggcatttg tcacgatgta aagatgctgc
     7921 aacgtactca gttcgccagt gaaaatggca agatcattag ccttcaaacc attgtcggcc
     7981 ggatcaaccg cctgataact gcgcagtgaa ctgcgtttaa cgtagccatc acgagaaacc
     8041 tgcaccatga cggtttcatc agccaccgtc accgttgtcg ccacttcaag cgtttcaatt
     8101 ttggcttgaa tgctgctgcg acgatcatcc ccgtactcct tggcaatccg cttcaactcg
     8161 ccttcaatca cccgatcgcg ggcagcgggg cgggccaaaa tatcttgata ctcggcgatt
     8221 gctttcgcca attgtgctgc ttctttctgt aaagccgtga tatcggtatt ggtcaatcga
     8281 tacagctgca aggaaacaat cgcttccgcc tgagcttccg aaaaatcaaa cttcttgact
     8341 aagttacgct tagcatctcc tttatccttg gaagcacgaa tcgcggcgat gacctgatcc
     8401 aaaatcgata gcattttgat caagccttcg acaatgtgct gtcgagcagc ggccttgttg
     8461 aggtcaaaac gcgttcgccg agtgaccaca tcgcgtcgat gttcgacgta tgcttccaac
     8521 atggccttga gtcctagcaa cttcggctgc atgtcggcaa tagcgaccat gttaaagttg
     8581 tatgcaattt gcagatcggt atttttaaat aaatagttta agatgccatg tgcatcggct
     8641 tcttttttta attcgatgac aacgctaagc ccaaaacgat cgctttcgtc acggacttcg
     8701 gcgataccgt ccactttttt gttgatgcgt aattcatcga tttttttaat catctgcgct
     8761 ttattgacat catacgggat ctcagtgacc acgatcttct cacgaccgcc acgaatggtt
     8821 tcgatgtgtg tccgagaacg aaccacgatt ttaccgcggc cggtttcgta agcttgcttg
     8881 atgccatcaa gcccttgaat aatcccacct gttggaaaat cgggaccctt gacgtattgc
     8941 attaaagtat ctaaatcagc agtgggatgc ttcagcaagt ataagacggc agcaataact
     9001 tcccgcagat tgtgcggcgg aatttcggtt gcataaccgg cagaaatacc ggtggcaccg
     9061 ttcaccagca aatttggaaa cccagctggc agcacagtcg gttcctgtgc cgtgtcatca
     9121 aagttcaaca ccatatcgac ggtttcctta tcgatgtcgg ccagcatttc cttgctgatt
     9181 ttgcttaaac gcgcttccgt gtatcgcatt gcagctggcg gatcaccatc catggaaccg
     9241 ttattcccgt gcatctgaat cagtggggcc cgtaacttcc aatcctggct tagccgaacc
     9301 atcgcttcat aaatggagct gtcgccgtgg ggatgataat tacccatgac attcccgaca
     9361 cttttagccg acttgcggaa gcccttatca tacgtattgc catcttggtt catcgcaaat
     9421 aaaatgcgac gctgaaccgg tttgaggccg tcacgcacat caggcagcgc ccgttcttga
     9481 ataatgtatt tcgagtaccg gccaaaccgg tcgcccatga cctcttctaa ggtcagttct
     9541 tgaatctgat tggccaatgg cttttacttt cctttcttgt ccagttgttt gacgatttgc
     9601 ttggcaccaa actgtaattt ttcgtgatta gcagtcgggg tttccaaaat actgccatcg
     9661 tcatccatat caaacttgac gttatgctca atccattcac gacgcggctc aacgcgatca
     9721 cccatcaaag tggtcacgcg tcgttccgcc agctgagcat cgtcaatccg aacccggatc
     9781 aaagtccgcg tctcaggatt catagtcgtt tcccaaagct ggtcggcatt catttcccca
     9841 agtcctttaa atcgggtcaa tgtgtaaccc ttgcccatgg ccttggtctc tttggccaac
     9901 tcttcatcgg tccaagcata actgatcttg gttttagcac cagcgccttt ttgcagccga
     9961 tacaatggtg gcaaagcaat gtaaattcgg cctgcgtcaa tcagcggccg catgtagcga
    10021 taaaagaagg ttagtagcaa aatctgaata tgcgcgccat cagtatccgc atcagtcata
    10081 ataatgattt tgtcgtagtt ggcctgctgc agatcaaaat ccgcaccgac accagcgccg
    10141 atggtgtaaa tcatcgtatt gatttcttcg tttttaacga tgtcctgtaa cttggccttc
    10201 tgagtattca gtactttccc tcgcaatggc aagatcgcct gaaacttccg gtctcggcct
    10261 tgtttagctg aaccaccggc agaatcccct tcgacgagat acaattcgtt acgcttaggg
    10321 ttcttggttt gcgccggggt taatttaccg gaaagcaagc cttgatcctt cttgcgcttg
    10381 cgtcccgtcc ggctatcatc gcgtgctttt cgagccgctt cccgcgcatc acgggctttg
    10441 acggctttac gaaccaactc ttgcgactct tcaccgtttt ccatcaaaaa agttgacagc
    10501 ttgtcataga caatcccatc gaccacagtg cgggcttgcg gcgtaccaag cttgcccttt
    10561 gtctggccct caaattgcaa aatttcttct ggaatgcgga cacttaaaat acctgcaaaa
    10621 ccttcacgca catcactgcc ttcaaggttc ttgtcgcgtt ccttcagcaa gccgactttt
    10681 cgggcaaatt cattgaatgc tcgcgtcatg ccgctgcgca agccaatttc atgcgtcccg
    10741 ccatcaccag tgcgaacgtt attaacaaac gaaatcaggt tttcagaata gccatcgtta
    10801 tattggccgg caaaatcaac cacgataccg tcctttttgc cttcaaaatt gatcacctgt
    10861 gacaatgcgt ctttgccttc attaaggtat ttaacaaaac tgaccaagcc atcaggatag
    10921 tgataactgt cgtgcttacc ggtgcgttca tccgtcagat taatcgtaat atttttcagt
    10981 agaaaggctg attcgcgtaa ccgttcggcc aaggtatcat aactgaaaac agtggtttga
    11041 aaaatagtcg gatccggctt aaacgtgatg gtcgtgccat taggttcatt aactttgccc
    11101 aacttctgca aactgccatc aggatgaccg ccattgataa aatgctcctc aaatgcgtgc
    11161 ttatcccgca caactcgcac agtcaatgac tccgataggg cattgacgac gcttgagcca
    11221 accccatgca aaccaccaga agttttgtaa ctattttggt taaactttcc gccggcatgt
    11281 agcacggtta aaatgacttc aatcgtcggt ttgccactcg ggtgcatccc cgttggcatc
    11341 ccgcgaccat gatcctgtac ggtcacagag ttatcggcgt gaatcgtcac attgatctca
    11401 tccccaaacc ccgcgagcgc ttcatcgaca gagttgtcca cgatttcata gaccaagtga
    11461 tgcaaaccgc ggccatcggt ggatccaata tacatccccg gacgcttccg cacagcttcc
    11521 aagccatgca gcacctgaat ggatgaatca ttatatgctt gcgttgcttt atccatagta
    11581 aactcccttt tttgaacaac taagttatag aatacaccac gcgttgagat ttcagaaata
    11641 aaaaataaga gcgcgagcca gcccgattag aaaccggagc ataagcggcc ttgggtgcga
    11701 tggttggact ttgaccattg cacccaaggt ccttacacgc aggttgctgc gagtgcgttt
    11761 aggcatcaac accatcaaca gcagacctca ccgtattgct ctcaggactc ctgttttctc
    11821 ctcaaaatcg acccagctgg ctaataccat cattgttcat ttaaatttta ttagccgtgt
    11881 caatgtccca aagctcagca gaaaaccgca cttccctaag catggcacat aactatgact
    11941 tcttgacgtg aaattcatcg cccgctggca ccaaatcgcg ccacaacccg cttcacaggt
    12001 tttattcgaa tgtacgttcg ttttattcta ctgacgtatc actcaaaagt caaaaatgct
    12061 aaaatagttt ctagtttgag aggaggggca catttgatac ttgtgctttg ttttatactc
    12121 gcgtatttca taggcgccat cccgtttggt gtggtcattg gtaaactctt ttatcacacg
    12181 gatatccgca aaggcgggag tcacaatatt ggcaccacaa atgcttatcg catgttaggg
    12241 ccagtcggcg gctcaattgt cttggtgctg gatatcttaa aaggcacgtt ggctgccagc
    12301 ttacccattc tctttggcat cgagcatcat tggctggtgc tgatcgtggg tttagcggcc
    12361 gtattcggtc atacattttc gatctacatt cgctttaaag gcggtaaggc ggtggcaact
    12421 agcgctggca ttttacttgc atataatccg ccattttttg tcattgcatt tgccatctgg
    12481 tttagtttga tcttgctaac gtccatggtc agcgttgcca gcacactggg tatggtgttg
    12541 atcacagctt ggtcgcttgt ttaccatgat tggttgctga caactgttgc ctgcgggttg
    12601 ctggttgtct ttttgatcaa acatcgggca aacttcaaac gcatcaaggc cggagatgaa
    12661 aatatggtgc cctttggctt aggccaatat cttcgtcaac accggggccg ctcttagtca
    12721 ccttttgatg gcaaccaaaa agacatccga aactggatgt ctttttttca tgtacctaat
    12781 cgacaaactg atgacacctt agaaaatgct aatcatgtaa cccttctcaa atgccgtgcc
    12841 aggttcaagt cgattaatcc cgagtttgcg cgtcaggtcg ccagtgctgc caatcgtgtc
    12901 ggcgatgccc caccaaggtt cgatgcagac aaagtcgcca gtggttggat acggactcca
    12961 aacgcccaga tatggggtat cggtcatggt aacactgaca ccatgtttcg tcttgtcaga
    13021 aaccaagttg aaggttgtct taccaagcaa cgcgaaaatt aaagcatcat gatcaaatgt
    13081 ttcgtgcgtt aaggccaaat tggcatcagt tgcagccaag gtccggtgcg tgtaatcaat
    13141 gccttcacca gcaaccaatg gaatctgaac aagcgactta cgcggtttga agttcaaata
    13201 ataatcggag aattgagtat ccggcgtcat tgggaccttg aagcccggat ggccgccgat
    13261 gctaaagaac agtggctcac ttttgtccgg attgtcaacg tgatacgtga catgtagatt
    13321 gttattttct agtgcaaacg tgatgattaa acgaaaagcg aacgggtaca tcgcccgcgt
    13381 tttgtcatca tccttcagaa cgaagctcgc tttaaacggt gtcgcagaga gcaccgtgaa
    13441 atcacgatca cgggcgaaac cgtgctggcc catgtggtaa gtcttgcctg cgtaatgata
    13501 ttgattgtca gccagcgccc caacaatcgg gaacaagacc ggggcgtggc gaccccacac
    13561 cgcaggatct gcttgccaca gacgctccct gcctgtcagg ttatctttga tactggtcag
    13621 ttcagcacca tgccgactga ttttaactgt caaaaagtca tttgcaatcg ttaccataca
    13681 tcctcatcct ttacctacaa cattattgtt aactacaaaa tataccgcgt catgtttgaa
    13741 tcagccgcaa tatggccaat cttatcatcc acatattgct gggtgacggt cacagcgccc
    13801 atcgccatat ctggaccttc ataaagtacg tcttcaagca gtttttcaag aatggtcgcc
    13861 agtcgccgcg ccccaatatt atcagtgtcg tggttgacct gagtcgcaat ctctgcaatt
    13921 cgatcaaccg cttccttcgt gaaggtaatc ttcacgccat ctgcaccaat caaggcgata
    13981 tactgcttga tcaaagcatt gtctggctcg gtcaagatcc gcacaaaatc tttttcggtt
    14041 aagtccttca attcaacccg aattggaaaa cgcccttgaa gttcagcaat caaatcacta
    14101 ggcttagcct cggcaaacgc acctgagcca atgaacaaga tgtgatccgt attgatagga
    14161 ccatacttag tgttaatctg cgatccttct acaatcggta aaatatctcg ctgcacacct
    14221 tcacgcgaaa cttcgccgct attatgcttg tttcccgcag caattttatc gatttcgtcg
    14281 atgaaaatga tcccgttatt ctcggcactt tgaatggcgt cgtgataaat gtcggcatga
    14341 ttgaccagtt tgtcagattc ctctttgatg aagatttcgc gagcttcttt gacggtcatg
    14401 gtccgctcaa cctttttctt aggcattaaa gcgccaatgg tgtcgcttag atcaatgccc
    14461 atctgaccgt acatgtcacc catgccaccg ccttttttct catcattgac agcaacggtg
    14521 atttcatgat cttcaagtaa tcccttttcc agttgctctg ccacgctcaa acgcttattg
    14581 cgaatatcat cggtcacttc gccgcctgcg tctgcatcat cgccagctgg cattttgcca
    14641 ttttgcatcc cttgcaacat gctcatcatc tcggccatcg gattggtatt cttttcctta
    14701 cgaatggccg gcactaaaat tttaaccaaa cgcttgttgg cttctttttc ggcacgtatg
    14761 cgaacctttg aaaattgctt ctcttcttcc atggcaacgg cagtttcggc aagatctcga
    14821 accatggatt cgacgtcacg gccaacgtag ccaacttccg taaacttagt cgcttccacc
    14881 ttcacaaatg gcgcctcaac tattttcgcc agtcgtcgtg caatttcggt tttcccgaca
    14941 ccggttggtc cgatcatcag taagtttttc ggggtaatct cttcttgcat ttttggcgat
    15001 aattgcattc gccgataacg gttatacaag gcaaccgcaa cggcccgttt tgcatcatct
    15061 tgtccaatga catattgatc gagtttttca acgatctgtt ttggggtttg tacttctgcc
    15121 atcataagcc tcctgtaggt caatgtaatt gccgacggtt acaaactaaa agctttcgac
    15181 aataacattg tggtttgtga aaatatcgat attccctgcg atattcactg cttctttggc
    15241 aatgtcagct ggtgtcatat ctggggcatg ccgcagcatc gcgattgccg cggcttgcgc
    15301 aaagttgccg ccggagccga ttgctaccac gtcttcatct ggatctatca cttcgccaga
    15361 cccggatacg agtaacaggt catgctcatc catcacgatc atcatggctt caagtttctg
    15421 caaggtcgga tccttgcgcc aatcttgagc cagcgcaact gcggaacgtc gcaagttgcc
    15481 cgcataatgc tccagcttct tttcaaacca gtcttgcagg gtgaaagcat ctgccacccc
    15541 gccggcaaac ccgatgacga cttgatcatg atagatccgg cgaactttct gcgcgttgcc
    15601 cttcatgatc accttttcgc caagggttac ctgaccgtca ccggccaaag cggtcacacc
    15661 atcttttctt actgctgcaa ttgttgtcat agtcatgctc ctttttaagt gagcgcgagc
    15721 agaagcactt agaaaccgga gcataagtgg gctggaagcc taaatggctg aattttggct
    15781 atttaggctt ccaggtcatt atgtgtaggt ttctgcgact gcgagcgcgt tatctgcgta
    15841 tttcgtcgga taaaaactgc taaagtagcg attaatctgt tatcgccaat gttcttagct
    15901 taaaaaactc agactgcttt tgcatcatgc tttagtctta attatgcttc ggataatatt
    15961 tcatatactc attttttaaa tgtgccatgg tgacatgcgt gtagatttgt gtggttgata
    16021 aacttgcatg acccagcagc tcttgaacag ttcgcaggtc agcaccatga tccagcatat
    16081 gggttgcaaa actatgccgc agcatgtggg gatgaatgtt agctgtcagc gtcgtctgct
    16141 taatgagctg atccaaaata tattcaatgc cacgcgaggt aatcggacgc ccatactggt
    16201 tcacgaatac atatcgatgc tgtgcctgac ttttagccat caagacttgt cggccatctt
    16261 ttaaataagt tcgtagtgct tgctgagcgt actgtccaaa gggcacatac ctatctttgt
    16321 tgcctttacc atgaatcaac agtaatgccg tattgaaatc gacctgattc aatgtcagct
    16381 tggcacactc ggaaactcga ataccggtgc catacaaaac ttccaacaaa gcgcgattac
    16441 gttgatccag cggggttttg ccagcaactg acttgaacag ttcctgaatc tcggcttcat
    16501 agaaaaattg tggtaaatga tgatgctgct tttttaattc aaccagctca aatgggttgc
    16561 gtttgacgac atcaattcgt gtcaaataac ggtaaaagct tcgcaaacta ctgatttttc
    16621 gggcaatcga tgtccgtgcc aaatcctgtt tgttaagatc agtcaaataa gtttgaacgt
    16681 ctaaatcatc cacatgccga aagtcagtaa acccgccgtt ggccttgaga aacgcctgaa
    16741 attcttgaag atcactcaaa taagccgtca ctgtttccgg tgaatactgc cgttcaactt
    16801 caagatactc ttgaaacgct gcaattggct tcattgaatc cctccgataa tacattaaca
    16861 t
//
