LOCUS       c00074_gnlPro..        13516 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DBMGEDCF_74.
ACCESSION   c00074_gnlPro..
VERSION     c00074_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 02:57:10
            Original ID  :: gnl|Prokka|DBMGEDCF_74
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13516
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13516
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1224:6926]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1225..6926
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..13516
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13516
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(267..362)
                     /locus_tag="ctg74_1"
                     /transl_table=11
                     /translation="MVHGQDHVMNAITFRDLAGEIVDLYKMLATK"
     CDS             complement(362..583)
                     /locus_tag="ctg74_2"
                     /transl_table=11
                     /translation="MNEQEQLVIMQLIMAGGNAKGSSFEAIKAAKVGDFSTAEAKLKEA
                     DSFLSDAHNAQTGMLTEEAQEKNIQYHY"
     CDS             complement(593..907)
                     /locus_tag="ctg74_3"
                     /transl_table=11
                     /translation="MGKKTIMLVCAAGMSTSMLVKKMEDAATKDGIEAKIFATSASDAH
                     DKLDSEKPDVLMLGPQVRYLEGDFKKDLSIPVQVINMQDYGLMKGENVLKTALKLIDEQ
                     "
     CDS             complement(1225..2979)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.9e-40, bitscore:
                     126.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKINAADAMIKVLEDWGIHNIYGLPGGSFDSTMNALYNRRHTI
                     NYVQVRHEEVGALAAAGEAKVTGRIGATFGSAGPGAVHLLNGLYDAQYDNVPVLALVGQ
                     VPTAAMNTNYFQEMNENPMFADVSVYNRTAMTAEQLPHVVDEAIRQAYKHNGVAVVTIP
                     KDLGWTQIDDNYVSSANLYQKPLLPDPDPDQVAAAWDILKDAKKPILYVGNGARGARDE
                     IIAFSEKTHIPIITTALAKGIVPDDYKANMGSAGRVASKPGVEVARGADTVLFLGSDFP
                     FQPYFIAPNAKYIQVDIDGSKFGRRHTVDLAVLADAKKFIKALSEKADQLPESAWYRAA
                     LANKENWREWMTSFEDDGSTPLRVEPIFKLINEMAEKDAIFQVDVGNVTINGMRYLKTN
                     DDQVFTTSGWYATMGYALPAAIGAQAEFPDRQVWSISGDGGFAMVMQDILTQVKYHMPI
                     INVVLTNESLGFIEAEQDDTQQPHSGVDLIDADYGKAAEALGAQGFEVHNLDELKAAFA
                     KAKDRKGPVVIDVKISDLRPIPVEQLVLDKQTQDPAAVDAFVKKYHAESLIPFRQLLED
                     AEKPVTNA"
     CDS             complement(3303..4469)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg74_5"
                     /sec_met_domain="ACP_syn_III (E-value: 1.9e-09, bitscore:
                     27.4, seeds: 136, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGIDAIAMDTPDFYVDLVKLAQVRGDDPDKYTIGIGQDEQAVP
                     PSSQDIVTMGANAATKLLTPAIRASLGMVLVGTESGVDASKSAALFIHDLLALPEWVRA
                     VELKEACYGGTAALMMARDYIAAHPDKTVLVIAADIARYGLATAGEVTQGAGAVAMLIK
                     AEPHIMTIEDDSVYRSESIDDFWRPVYQDTAIAQGKYSTEQYLAFFQAIWSRYQTQRHH
                     TASDFAAMTFHLPYTKMGKKALKLVLPDTDEATGERLQRRFEASTRYCRRVGNIYTGSL
                     YLGLLSLLDNDTSLKAGDRIGLFSYGSGAVAEFFSGILQPDFAAQLHAANHAKMLADRQ
                     ELTVPEYEAVFSDKVPYDPEDYRSDPTYYHGQFVLTGVIGQERQYQQR"
     CDS             complement(4453..5733)
                     /locus_tag="ctg74_6"
                     /transl_table=11
                     /translation="MKFYELSPEKRRDQLVQEGWLTTQDAALLAGTHSLPEVTGARLIE
                     NAIGEFPLPLGVARNLLVNGQLHQVPIADEEPSVIAAASNGARLATANGGVRTHVAAHR
                     VVAEVVLTNLTDLVQARQTILAHQTDIQRVIAVAHPSMIQRGGGLDQLTVESLGAQFLK
                     IRLTLDPQQAMGANYANTVAEAVAAAVTSWVDGDVLVSILTNAPTELVTAEVSLEPVSL
                     ATKAVSGDVIAKKIVQLSDLAFVDAERAVTHNKGILNGIIGAVLATGNDTRAVAASIGA
                     FACASGRYQPLSRWYMDQGHLVGHLQLPLPMGAVGGAIGALPMAQVVRRLGGYQNLAIM
                     QQVIAALGLVQNLAAMRALAGPGIQAGHMKLQANALAIAAGATETELPMLVNALRQGSM
                     DLKHAQQYLTTIRLNKKVGQSKDENRD"
     CDS             complement(5745..6926)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_7"
                     /sec_met_domain="Thiolase_N (E-value: 1.2e-94, bitscore:
                     306.4, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 3.3e-44, bitscore:
                     139.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEVVILSAKRTPIGKLGGDLAGASAVDLGVAAAQAAIKAARIDP
                     ALLNQAIFGNVMQAGSGQNVARQIGLKSGMATSSTAMTVNEVCGSGLKAVRLGQAAIQL
                     GEADAVLVGGTESMSQVPYYAEAVRSGHKFGDTTLVDGLSRDGLNDAFSQQPMGITAEN
                     VATQFNVSRQEQDEFALRSHLRAAAAAAEGRFKSQIAPVTIAARHGDVIVDRDSAIRPD
                     TSLAKLAQLPPVFEVGGTVTAGNASGINDGAAALILMAKSKAEQLGLHYLATITGFAEV
                     GIDPAIMGYAPKLAIDKILQATGGSIAAIDQIELNEAFASQSVAVARDLGLKDEQFNIN
                     GGALALGHPLGASGARILISLLYDLAERNQRQGIAALCVGGGIGIAMQIAMHV"
     CDS             7271..7570
                     /locus_tag="ctg74_8"
                     /transl_table=11
                     /translation="MRVTDLLALLADQNKNASVLLDTKPTPSRFDDFKLTTVNDQPQLV
                     FQPNPERKAALRVWELQLLLNQPDLQQRFVYLADVDEPRALFGFVKRQIGLLLN"
     CDS             complement(7571..8401)
                     /locus_tag="ctg74_9"
                     /transl_table=11
                     /translation="MLLGLKASTDQRQIRDRLQYHPDVFEFHLTENDFTEAGWSHFVQM
                     AALVQSQVPTVVFHHPMRFRGQRNELAMNPTKYSTRYDFLMTSSVKLMNFAKKANATAL
                     IHGGYRVDTPGDYAGWTDVGKAQDVALARMIAFAQEAPGHVVFENSMSPIFRYGDPTFE
                     DRLLRWHLPLAYDTSHTFIVLHGDNDRLMASLAHLKPLIRHYHLVDSMGQTHDSLPLGR
                     GRIDWARVLPLLNQDASRIYEIGLKDQFDCREMIESHHYLESVAKRLAATKHPA"
     CDS             complement(8549..9061)
                     /locus_tag="ctg74_10"
                     /transl_table=11
                     /translation="LGLAYSFWARSFLPRQLRQYGDPASFGIISLFVVINAIMLYHHHF
                     RFRDLKMETVDIMEGEKFESFCAYLLKRNGFNHIQLTQASGDQGIDIIARKKGKTIGFQ
                     CKRYTGFVGNKAVQEVWAGHHFYQLDEAAVITNSEFSDSAIALADDLGVMLIDRKKLKR
                     LMRRLPS"
     CDS             9226..10044
                     /locus_tag="ctg74_11"
                     /transl_table=11
                     /translation="MQLSAKIFAKVGSERITQYSLVNDHQMTLRFLTFGARVQQVRLPN
                     AAGDDPNLLLGFVTLEDYLHQPGYLGAFTGPLQAADAELAPGSWQNWNWAVKTSQETDL
                     AITFTLTLPENADGQPGQRELSITHRLTNDNLWQIDMQVATTADLKIHPRLNLPWLLTA
                     DPAQTMLSAKLTADEHVTPVPKTARCETAQRYSLAAADWQLAYLSDASFTRIDSYAGIN
                     SENNFNGILGQPNVAVGFSPEMNQDALPWLLPAGATWRHHAEFHLSSNAN"
     CDS             complement(10104..11243)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg74_12"
                     /sec_met_domain="Peptidase_M20 (E-value: 1e-35, bitscore:
                     113.3, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTEEEQVVDLLSAMVKIPSVAAKEGQVADLIETFLAPELKAGLIK
                     QERISYAPGRDNLVLTIGNPNAQRWLGVDGHMDVVDPGNVNKWQFPPFSAHVEDGKLYG
                     RGATDVKSGLAAAVMAFKQAAHEKLDHGIQLMATVGEEVDNDGARQLSAAGYGDRLTGL
                     LVAEPGNSNVDAAERGIIDYTLTAHGKAAHSSRPDLGANAIHGLFAFANAALTATAPLQ
                     AKEDPILGHATHNIDIIHGGNQINSIPESAYLRGNIRTTMIADNDAFIAALKQAAKTTV
                     PKGVRLSLSIDSVLGAAAASPDNDLIQLVQTARQRAGLNRGQVAYRTGITDAALFYHDG
                     LDLAIYGPGNETSHETDEYVTLKDVFDSVKVFKDVFMNY"
     CDS             complement(11322..11927)
                     /locus_tag="ctg74_13"
                     /transl_table=11
                     /translation="MTQRGKAYNIAIIGILGALIILQAYIPMVGYVQIFPAWPAISTIH
                     LTVIIGGIVLGYGGGASLGLLWGLTSLIRAYTSATDPVTLLLFRNPIIAIVPRVMVGLV
                     AAFIFHQLFKKKQTPLAQTVKMVFAGVVGALTNTLLVIGFTWLMFASKAAQIVPGADAT
                     NLGWLLMTALAINAVAEALLGGIVTPILGHALLRFRRK"
     CDS             12567..13031
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg74_14"
                     /sec_met_domain="Acetyltransf_1 (E-value: 8e-17, bitscore:
                     51.6, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLREAQFIDLGAIVHLYQQLTAEMATMAPETYRPLTSDNRQYFAD
                     YLQNDLARLFVTETAGTLSGFALVVLARTGDNAEFVPQHFAQLIDLYVIPAQRHQGLAK
                     QLMDAVTAFAKSHDATFIQLNVLNANQTAKQVYAKAGFEPVSLILQKPLN"
     CDS             complement(13024..13476)
                     /locus_tag="ctg74_15"
                     /transl_table=11
                     /translation="MTDQELQARVEAISLKAFHQPFRHHAVFNNRLKTTGGRFHPADMN
                     LDFNPKLFAVYPASVTDGIIKHELVHYHLYDHHRGYQHRDHDFKQLLTAVGGSRFAPPL
                     PVNGHQYVYVCTHCGRQFVRRRHIDVRRYACGVCRGKLRLQKTLAS"
ORIGIN
        1 ctcttcgcca gtacttactt acttgttcaa ccgctaccac tgcatttata acggtcaaac
       61 aaaacggtac ccatttcatc gcgccctgtg tgcccaaaac taagaaaaaa accaatataa
      121 atttgcaaag aaaaaaccgg cggtcacgta acggattaat aaatagcgat taaagtacat
      181 actagttaag cttaattctc tccgactctt gtcatatctt gctttatttt ggtctgacat
      241 gcgtgtcaca ttcctttcgc ttagacttat ttcgtagcta acattttata gaggtcaacg
      301 atttcccctg ctaagtctcg aaatgtgatt gcattcataa catgatcctg tccgtgcacc
      361 atcaataatg atactggatg tttttttcct gagcttcttc ggttaacata cctgtttgtg
      421 cattatgtgc atctgacaga aagctgtctg cctctttcag tttggcttct gcggtagaaa
      481 aatcaccgac ttttgcagct ttaattgcct caaaagaaga tccttttgca tttcccccgg
      541 ccataattag ctgcatgatc actagttgct cttgctcgtt catcctgacc tcctactgct
      601 cgtcaatcag cttaagagcc gtttttagaa cattttcgcc tttcattaag ccgtaatcct
      661 gcatattgat cacttgaact ggaatactaa gatccttttt gaaatctccc tctaaataac
      721 gcacttgtgg tccaagcatc aggacatctg gtttttctga atctaacttg tcatgggcat
      781 ctgaagctga agtagcaaag atttttgctt caataccatc tttggtcgct gcatcttcca
      841 tttttttgac taacatactg gttgacatac ctgctgcaca aactaacata attgtcttct
      901 tacccattag tttttcctcg ctttcaaaat ttcaaagtta ttgttcacca cagaatgact
      961 ttttaatatc agcatactcg ctagcttaac gagccatatc agaagtcatt cgaatgacta
     1021 ttcgttcgaa cgacttttat aataccaaga aatcgctttc ttgtaaacga tttcttgaat
     1081 tttttgaaat tttgtctcta cgccttatcg caaaaggccg gcaactgata atgaaggctt
     1141 caaatagcga taagcaaaaa aagccttcca gcaaggcata ttaattgctg gaaagctttg
     1201 taatttatat tttaagtcaa ccagttaagc atttgttacc ggtttctccg catcttccag
     1261 taactgtcgg aatggaatca gactttctgc atgatatttc ttcacaaaag catccacagc
     1321 agcaggatcc tgagtttgct tgtccaaaac aagttgttca accggaattg gccgaagatc
     1381 agaaatcttc acatcaatga caaccggacc cttacgatct tttgccttag caaatgcggc
     1441 tttcaattcg tccagattgt gcacttcaaa tccttgagca cctaacgctt cagctgcctt
     1501 accataatca gcatcaatta aatcaacccc ggagtgcggc tgttgcgtgt catcctgttc
     1561 agcttcaata aagcctaaac tctcattcgt caaaacaacg ttgatgattg gcatatgata
     1621 tttgacctgt gtcagaatat cctgcatgac catggcaaat ccaccatcac cagaaattga
     1681 ccaaacttgc cgatcaggga attccgcttg cgcaccaatc gctgctggca aggcataacc
     1741 cattgtcgca taccagccag acgtcgtgaa cacttgatca tcattggtct tcagataacg
     1801 catcccatta atggtaacat tgccaacgtc tacttggaaa atggcatctt tttcggccat
     1861 ctcattgatc aatttgaaga ttggttcaac gcgcagtggc gtggagccat catcttcaaa
     1921 tgaagtcatc cactcgcgcc aattttcctt gttggccaga gcagcccgat accaagcgct
     1981 ttctggcaat tgatcagcct tttcgctcag tgccttgatg aacttcttag catcggccaa
     2041 aacagctaag tcaacggtgt gacgacggcc aaacttgcta ccgtcaatat caacctgaat
     2101 gtatttagca tttggtgcta taaagtatgg ctggaatggg aaatccgatc ccaagaacaa
     2161 gacggtgtca gcaccgcgcg caacttcaac gccaggttta gaagccacac ggccggccga
     2221 gcccatgttt gccttataat catcaggcac gattccctta gccaaggcag tcgtgatgat
     2281 cggaatatgc gttttttctg agaaagcgat gatctcgtcg cgcgcacccc gcgcgccatt
     2341 tccaacatac aagattggct tcttcgcatc tttcaagata tcccaagctg cggcaacctg
     2401 atctgggtct ggatcaggca aaagcggctt ctggtacaga ttggctgatg atacataatt
     2461 gtcatcaatc tgggtccaac ctaaatcctt tggaattgtc acaacggcaa ccccgttatg
     2521 cttataagcc tgacgaatcg cctcgtcaac aacatgaggc aattgctcag cagtcatggc
     2581 tgtacggttg tatacagaca catcagcaaa cattgggttc tcgttcattt cttggaaata
     2641 attggtgttc atggcagcag ttggtacttg ccctaccaat gccaaaactg gcacattatc
     2701 atactgtgcg tcatacaacc cattcagaag atgaacagca ccaggaccgg cagaaccaaa
     2761 cgtcgccccg attcgacccg ttaccttagc ttcacctgca gcagccaatg cgcctacttc
     2821 ttcatggcga acctgaacat aattaatggt gtgacggcga ttgtacagcg cattcatggt
     2881 actatcaaaa gaaccgcccg gtaacccata aatattatgg ataccccagt cttcgagcac
     2941 cttgatcatt gcgtctgcgg cgtttatttt ttctgtcatg acacttgcct ccaatattat
     3001 tacttacatt ttgtaagttc tttacgatta cgagtataac aatttattga taacaatgca
     3061 agccctttca tctggtttaa gcaaccttaa cgcccaaatt gcgaccttag cgtataaaac
     3121 gcttaaacta gcaagcgacg acaccataac agtcaaacaa gtgaactaat acagcatcac
     3181 cacgccataa catgcttggt aaaccttttt cacaaattaa cttaatgatg atcaggatca
     3241 tggatcaaaa aaagggaccg tcgagggacg gtcctgttca tcatcttatt agctgtcaag
     3301 cattaccgct gctgatattg acgttcttga ccgatcacac cggtcaaaac aaactgacca
     3361 tgataataag tcggatcact acgataatct tctggatcat aaggcacctt atcgctgaaa
     3421 acagcttcgt attcaggaac ggttaattcc tgacgatcag ccaacatttt agcatgattg
     3481 gctgcatgca gttgtgcggc aaaatccggt tgcaagatgc cgctaaaaaa ttctgccacg
     3541 gccccggaac catacgagaa taaaccgatc cggtcacccg ctttcaagct agtatcattg
     3601 tccaacaacg acagcagacc caaatacaaa gaaccggtat aaatattgcc aactcgccgg
     3661 cagtaccgag tgcttgcctc aaagcgccgt tgcagtcgct cgccagtggc ttcatctgtg
     3721 tccggcagaa caagctttaa agctttcttg cccattttgg tatacggtaa atggaatgtc
     3781 atcgcagcaa aatcacttgc tgtgtgatgg cgttgggtct ggtatcgtga ccaaattgct
     3841 tgaaaaaaag ctaaatattg ttccgttgaa tactttcctt gtgcaattgc tgtgtcttga
     3901 taaaccggcc gccaaaaatc gtcaatagat tcagaccgat aaaccgaatc gtcttcaatg
     3961 gtcatgatgt gcggctctgc tttgattaac atggcaaccg cgcccgcacc ttgtgtgact
     4021 tctcctgctg ttgccaaacc gtaccgggcg atatccgcag caatgactaa aacggtttta
     4081 tctgggtgag cggcgatgta gtcacgcgcc atcattagtg cggcagtacc gccataacaa
     4141 gcttccttta actcaacggc ccgcacccac tcagggagtg ccaataaatc atgaataaac
     4201 aatgcagccg atttactggc atcaacacca ctttcagtac caaccaagac catgcccaag
     4261 ctagcgcgaa tcgctggcgt caacaacttt gtcgctgcat tcgcacccat cgtgacaatg
     4321 tcttggctag aaggtggtac cgcttgctcg tcttggccaa tgccaatcgt atatttgtcc
     4381 ggatcatcac ctcgaacctg cgcgagtttt actaaatcaa cgtagaaatc tggggtgtcc
     4441 atagcgattg catcaatccc gattttcatc ttttgattgg cctactttct tgtttaaacg
     4501 aatggttgtt aaatattgtt gcgcatgttt taaatccata ctaccttgac gaagtgcgtt
     4561 cacaagcatc ggcaattctg tttctgttgc cccggcagca atggcgaggg cattagcttg
     4621 caacttcatg tgaccagctt gaatccccgg tccagccaat gctcgcatcg cagcaagatt
     4681 ttgcaccaac ccgagggcgg caataacttg ctgcatgata gctaaattct gatacccacc
     4741 gagccgacgg acaacctgcg ccattggtaa agcaccgatc gccccgccaa ctgcccccat
     4801 cggcaagggc agctgtaagt gaccaactaa atggccctga tccatatacc agcgcgataa
     4861 aggctgatac ctgccagacg cacatgcaaa tgcaccgata cttgctgcga cagcgcgggt
     4921 atcattgcca gtagccaata cagcaccaat aataccgtta agaatgccct tgttgtgggt
     4981 cactgcccgc tcagcatcga caaaggctaa atcgctaagc tgaacaattt tcttagcaat
     5041 cacatctcca gaaacagctt tcgtcgctaa agaaaccggc tcaagcgaaa cctcagccgt
     5101 cacgagttct gttggcgcgt tggttagaat actgacaagc acatcaccgt ctacccagct
     5161 tgtcaccgcc gctgcgaccg cttcggcaac tgtattcgca taattggccc ccattgcctg
     5221 ttgcggatcg agcgttaaac ggattttcaa gaactgtgct cctagtgatt cgaccgttaa
     5281 ctgatcaaga ccaccgccac gttgaatcat cgaaggatgc gcaaccgcaa tgactctctg
     5341 aatatcagtc tgatgagcca aaatcgtttg ccttgcttgc actaagtccg tcaagttagt
     5401 caggactact tcagcgacca ctcgatgcgc cgctacatgg gtcctaacgc cgccgtttgc
     5461 agtcgcaagc ctggccccat tactggcagc tgcaatcaca gaaggttcct catccgctat
     5521 aggcacttga tgtagctgtc cattgaccaa caaattgcga gcaacgccta ggggtaaagg
     5581 aaactcgccg atggcatttt cgatcagacg cgctcctgtg acttcaggca agctatgcgt
     5641 accagctaac aacgcagcat cctgtgttgt taaccaccct tcttgaacca attgatcacg
     5701 gcgcttttcc ggagacaact cgtaaaattt catcacgatc tccctcagac atgcatcgcg
     5761 atttgcatgg cgataccgat gccaccgcca acgcacaatg cggcaatgcc ttggcgttga
     5821 ttacgttcag ccagatcgta caataatgag attaaaattc gggcacctga agctcccaat
     5881 ggatgaccca acgctaaggc gccaccattg atattgaatt gttcatcctt taaaccaagg
     5941 tcacgagcca cagcaacgct ttgtgaggca aatgcttcat tcaattcaat ttgatcaatt
     6001 gccgcgatag agccgccggt tgcctgcagt attttatcga tcgccagttt tggcgcatac
     6061 cccataattg ccggatcaat acccacctcg gcaaaaccag tgatcgtcgc taaataatgg
     6121 agccccagtt gttcggcttt cgattttgcc atcaggatca aggcggctgc gccatcatta
     6181 atgccgcttg cgttacctgc tgtaacagta ccgccgactt caaaaacagg cggtaattgg
     6241 gctaatttag ccaatgacgt atcgggccga atggctgaat cacgatctac gatgacatcc
     6301 ccgtgacggg cagcaatcgt cactggggcg atctgactct taaaccgacc ctcagctgcg
     6361 gcggccgcgg cgcgtaaatg cgaacggaga gcaaactcat cttgctcctg acgactaacg
     6421 ttaaattgtg tcgccacatt ttccgccgtg attcccattg gctgctgact gaaggcatca
     6481 tttaatccat cgcgactcaa accgtcgacc agcgttgtat cgccaaattt gtggcctgaa
     6541 cgaaccgctt cggcgtaata aggtacttga ctcatgcttt cggtaccgcc cacaagcacc
     6601 gcgtcagcct cgccgagttg aatggcagct tgcccaagcc gcactgcctt caggcctgag
     6661 ccgcagactt cattgacagt catcgccgtg ctgctagtgg ccataccgct ttttaatccg
     6721 atttgtcggg caacattctg cccagaacca gcctgcatga cattaccaaa gatcgcctga
     6781 ttgagtaacg ctgggtcaat tcgtgcagcc ttaattgccg cctgcgctgc cgcaacccct
     6841 aaatcaacgg cactggcgcc agccaaatca ccacccaact taccaatcgg cgtccgtttg
     6901 gcacttagaa tcacaacttc ttccatgatg acctcctaaa gagcgtgaac agccaaccgg
     6961 cgcataatca agaacgaggg caatggccga gccattgttc tcgtggttct gatgtgccgg
     7021 tttctgtggc tatgaacgcg tttcgacaag catatgctga gataaaccgt ttcagtttat
     7081 cacagtcgtt cagatgacgc actgatataa taagagcgtg agccaacccg gttacaccga
     7141 cttttgggtt ggcgatcgcc taaaaacgct actcatctcc gtttactaaa tagattgtat
     7201 gcgattgttc cccaaagcaa caaccatctt gaccaatcct taatgaatca tttcgaaaga
     7261 aggctacctc atgcgtgtca ccgatttgct ggctttacta gccgatcaaa ataaaaacgc
     7321 ctcggtgtta ctcgacacaa agccgacacc aagtcgtttt gacgatttta agttaacaac
     7381 cgttaatgat caaccgcaac tggtctttca gcctaatcct gagcgcaaag ccgcattgcg
     7441 cgtttgggaa ttgcaactct tactgaacca acctgattta cagcaacgat tcgtttatct
     7501 agctgatgtt gatgaaccgc gtgcgttatt tggatttgtt aaacggcaaa ttggcttgct
     7561 gctcaattga ttacgctgga tgtttggtcg cagctaaccg tttagcaacg ctttccaaat
     7621 aatgatgact ttcaatcatt tcccgacaat caaactgatc ctttaagcca atttcataaa
     7681 tccgactcgc atcttgattc aatagtggca agacccgcgc ccaatcaatc cgtccgcggc
     7741 caagcggtaa actatcatgc gtttgcccca tggaatcaac aagatgatag tgccgaatca
     7801 gcggcttcag atgcgctagg ctggccatga gccgatcatt atcgccatgt aacacaataa
     7861 acgtatgact ggtatcatag gctaaaggta aatgccagcg caacaaacgg tcttcaaagg
     7921 tgggatcacc atatcggaaa atcggtgaca tggaattttc aaacacgaca tggcccggtg
     7981 cttcctgggc aaaagcaatc atgcgcgcca aggcaacgtc ttgtgctttg cccacatctg
     8041 tccagccagc ataatcacca ggcgtgtcaa cgcggtatcc gccgtgaatc aaagccgtgg
     8101 cgttagcttt tttggcaaag ttcatgagtt taaccgaact tgtcattaaa aagtcatagc
     8161 gtgtagaata cttcgtcgga ttcatggcaa gctcattgcg ctggccgcga aaccgcatcg
     8221 gatgatgaaa aaccaccgtt ggcacctgac tctgaactaa tgctgccatc tgtacaaaat
     8281 gcgaccatcc agcttcggta aaatcatttt cggtgagatg aaattcgaat acatcaggat
     8341 gatattgcag ccgatcacga atctgccgct gatctgtact agcctttaag cctaatagca
     8401 tgtacacttt tcctccttaa ttcaaaaccc gctcatgatc ccaaaaattg cacataagaa
     8461 cgttaagcat cgctgaccaa ggctctaagc agcttctgct aagctttcga agcgctccta
     8521 cttgcacttt caaatttcag ttgtcttttt aacttggcaa ccggcgcatt aaacgtttca
     8581 attttttacg atcaatcagc atcacaccca agtcgtcggc caaggcgatc gccgaatcag
     8641 aaaattcgct attggtgatc actgccgctt cgtcgagctg gtaaaaatga tggcccgccc
     8701 aaacttcctg cacggccttg ttgccaacga aaccggtgta gcgcttgcac tgaaaaccaa
     8761 tcgtcttacc ttttttgcgg gcaataatgt caattccttg atcacctgaa gcctgcgtca
     8821 gttgaatgtg attaaaccca ttgcgcttca acagatacgc gcaaaaagac tcaaactttt
     8881 caccctccat gatatcgaca gtttccattt tcaaatcacg aaaacgaaaa tgatgatgat
     8941 aaagcatgat ggcattgatc acaacaaaaa gactgatgat tccaaaacta gccggatcac
     9001 catattgccg cagttggcgg ggcagaaaac tgcgggccca aaagctgtaa gcgagtccca
     9061 aaataaagag cccccacaac agctgatagg ctttttttga gtaacgttct catgggtcta
     9121 cccctctctt tccttttaag cctagcagat tcaccgcgta attgcattga atctctgcca
     9181 atttttctgt acgcttaagg gattgagaga ggaagcgttt tcgtcatgca actaagtgcc
     9241 aagatctttg ccaaagtcgg tagcgaacgg attacccagt attctttagt caatgaccat
     9301 cagatgacgc tacgtttttt aacgtttggc gctcgggttc aacaggttcg cctgccaaat
     9361 gctgcaggtg acgatcctaa tctgctgctc gggttcgtca cgctggaaga ctacttacac
     9421 caacccggtt acctaggcgc ctttaccggc cctttacagg cagctgacgc tgagctagcc
     9481 ccgggttcat ggcaaaactg gaattgggcg gttaaaacca gtcaagaaac cgatctagcc
     9541 atcaccttca ccctaacatt acctgaaaat gctgacggtc agccaggtca gcgagaactc
     9601 agtattaccc accgattgac aaatgacaat ttgtggcaga ttgacatgca agtggcaacc
     9661 actgccgact tgaaaataca tcctcggctc aatttgcctt ggctgctcac tgccgaccct
     9721 gcccaaacaa tgctttcagc caagttgact gccgatgaac atgttacccc tgtccctaaa
     9781 accgcccgct gtgagactgc gcaacgctat tcccttgcag ccgccgattg gcagttggca
     9841 tatcttagcg acgcctcatt cacgagaatt gattcttacg ctggcatcaa ctccgaaaat
     9901 aattttaacg gtattctcgg ccaacccaat gtagcagtcg gcttttcgcc ggaaatgaac
     9961 caagacgctc tgccgtggct gttgccagcc ggtgcaactt ggcggcatca tgcggaattt
    10021 cacttatcca gcaacgcaaa ctaaaaaggt ttgaccccac ggtatctgtt gtggggtcaa
    10081 accttttttc caatcagtga tgattaatag ttcataaaaa catccttgaa gactttaaca
    10141 ctgtcaaaga cgtcttttaa agtgacgtat tcatccgtct catgagacgt ttcatttccc
    10201 gggccataaa tagctaaatc aagaccgtca tgatagaaca acgccgcatc cgtgatgccg
    10261 gtgcgatagg ccacttgacc acgattcagc cccgcacgtt gacgggctgt ctgtaccaac
    10321 tgaatcaaat cattatcagg tgaagccgca gctgcgccta aaacggaatc aattgacaga
    10381 ctcaaccgaa cacccttagg cactgtcgtt ttagctgctt gtttcaacgc cgcaataaac
    10441 gcatcattat ccgcaatcat ggttgtccgg atgttaccgc gcaaatatgc ggactccgga
    10501 atcgagttga tctgattgcc accatggata atatcaatat tatgcgtggc atgaccaaga
    10561 atggggtcct cttttgcctg caacggcgct gttgcagtta gcgctgcatt cgcaaatgca
    10621 aacaacccat gaatggcatt tgcccctaaa tctggccgag acgaatgtgc tgctttcccg
    10681 tgcgcggtca atgtgtaatc aataataccg cgttcagcag cgtcaacatt gctattgccg
    10741 ggttcggcca caagcagtcc agttaaacga tctccgtaac cggcggcaga cagttggcgt
    10801 gcgccgtcat tatcaacttc ttcaccaact gtcgccatca attgaatccc atgatccaat
    10861 ttttcatggg cagcttgctt gaatgccata accgctgcag ccagtccaga cttcacgtca
    10921 gttgcaccac gaccgtacaa cttgccatct tctacatgtg ctgagaatgg tggaaactgc
    10981 catttattga cgttcccagg gtcaaccaca tccatatggc catccacacc gagccagcgc
    11041 tgggcattag gattaccgat cgtcagcacc aaattatcac gaccgggcgc ataactgatg
    11101 cgttcctgtt taatcaatcc ggctttcaac tcaggggcta aaaaggtttc aatcaggtct
    11161 gctacctgac cttcttttgc tgccacactt ggtatcttta ccatggcact gagtaaatca
    11221 acgacttgtt cttcttctgt caagataagg cctccactta tgatcgtttg tattctgctt
    11281 ttgtttggct tcggacagcc gctcagcaca acatttaacg cttatttccg tctgaatcgt
    11341 aataatgcat gacccaaaat tggtgtcacg ataccgccca acaaggcctc ggctacggcg
    11401 ttaatcgcca aagccgtcat caataaccat cctaggttgg tcgcatccgc acccggcaca
    11461 atttgcgctg ctttactggc aaacatcaac catgtaaacc caatgaccag caaggtgttc
    11521 gtcaaagcac cgacaacacc ggcgaaaacc attttaactg tttgcgccaa cggtgtttgt
    11581 tttttcttga acaattgatg aaaaataaat gcagccacca aaccaaccat gacacgcggc
    11641 acgatggcga taatcggatt tctaaacagc agcagggtca ctggatcagt cgctgatgta
    11701 tacgcccgaa tcagactggt taacccccat aataagccaa ggctggcacc gccgccatag
    11761 cctaatacaa taccaccaat gatgactgtc aaatgaatcg ttgaaatcgc aggccaagcc
    11821 ggaaaaatct gcacatatcc gaccattgga atataagcct gaagaataat caaagcacca
    11881 agaataccaa taatcgcaat attataagct tttccgcgtt gcgtcatgcg ctgctacctc
    11941 caaattgtct aagtttgatt ttatcaaatt atacacgttc gaggaaagtg atgctgggag
    12001 gaagactttt actggaaacg ctagggaaaa ggttggctgt taaagggttc ccgcgatggc
    12061 gttgcacaaa acacgctcgt agttggagaa gactacacat aaagacctca taaataaatg
    12121 actgaaaacc ggtcattgac ttatccgccg gtttctaaac gcgttcgcca ccccagaaac
    12181 ctgcgtgtaa ggaccttgac cggaatgacc aaacccaggc catcacggtc aagtccgcct
    12241 acactccggt ttctaaccgg ggtggcgaac gctcttgaaa aataaagttt gactttaaat
    12301 ccctaatttc ctataatatt tcttgtgctt aattagccat gcgggcatgg cggaattggt
    12361 agacgcgcaa gattaaggat cttgtgagca ttattgctca tggaagttcg agtcttcttg
    12421 cccgcatcac aaaagacccg accaacagga catcttgttg gtcgggtctt ttgtgccacc
    12481 ttagattttc taactaccgg caaggctctc tagcagctgt tttaatcaat tatcatgtca
    12541 cacaagtcat tgaaaggagt ttctctatgc ttcgcgaagc tcaatttatc gatctcggtg
    12601 ccattgttca cctctatcaa caactaaccg ctgaaatggc gacgatggcc cctgaaactt
    12661 atcgtccatt aactagcgac aatcgtcaat attttgccga ctacttgcaa aatgaccttg
    12721 ctcggctttt cgtgaccgaa acggctggta ctttaagtgg gtttgcactt gtcgttttgg
    12781 ctcgcactgg cgacaatgcg gaatttgttc cgcaacattt tgcccagctg attgatcttt
    12841 atgtgatccc tgcgcaacgg catcagggat tggctaaaca gcttatggac gcggttacgg
    12901 cttttgccaa aagccatgat gccactttca ttcagttaaa cgttttgaat gccaatcaga
    12961 ctgccaaaca agtctatgcc aaagctgggt ttgaaccggt aagtctgatt ttgcaaaaac
    13021 cgcttaacta gccaacgtct tttgcaggcg caatttaccg cgacagacac cacacgcgta
    13081 ccgccgaaca tcaatgtgcc ggcgacgaac gaattggcga ccgcaatggg tgcatacata
    13141 cacgtactga tggccgttca ctggcaacgg tggcgcaaaa cgtgacccgc caactgcagt
    13201 caagagctgc ttaaagtcgt gatcgcgatg ctgatagccg cgatggtgat catataggtg
    13261 gtaatgcacc agttcatgtt taataatgcc atcggtgaca ctcgcaggat aaaccgcaaa
    13321 tagcttgggg ttgaagtcta agttcatatc agccggatga aagcggccac ccgtcgtttt
    13381 tagccgatta ttaaaaacag cgtgatggcg aaaaggttga tggaatgctt tcaacgaaat
    13441 cgcctcaacg cgggcctgta attcttgatc tgtcatatct acctccgagc caatagttta
    13501 ctccaagtca cccgta
//
