LOCUS       c00048_gnlPro..        16383 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FAKHHOAB_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 02:43:58
            Original ID  :: gnl|Prokka|FAKHHOAB_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16383
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16383
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3138:6383]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3139..6383
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16383
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16383
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(1084..2016)
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVFDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAEPVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELISAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSTFEG"
     CDS             complement(2046..3014)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg48_2"
                     /sec_met_domain="LysR_substrate (E-value: 2e-27, bitscore:
                     85.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6.7e-20, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWATYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             complement(3139..3990)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_3"
                     /sec_met_domain="Radical_SAM (E-value: 3.4e-26, bitscore:
                     82.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSAERVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             complement(4122..6383)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_4"
                     /sec_met_domain="Gly_radical (E-value: 5.2e-42, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.2e-244, bitscore:
                     802.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDETKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTHNQGVFDAYTPDMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLTGDGEMTDDVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMHDKYYYEAAQLALKDTQLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADNDDYPRYGNNDDRADDIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFEEM
                     "
     CDS             complement(6635..9079)
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVINAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDRFGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNMVAIADMQPKL
                     LGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQVIAAIRASKDK
                     GDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIAEYQDILARPA
                     ARDRVIEGELKRIAKEYGDDRRSSIQAKIETLEVATTVTVADETVMVQVSRDGYVKRSS
                     LRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGE
                     HLSQTVGLGTDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTYKSKPMMA
                     MKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATGVKSMDLKPDD
                     EVVNFILVKDPTTAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAM
                     MSVDDATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTDVLGKPVFVQTKEEPADQ
                     VE"
     CDS             complement(9086..11098)
                     /locus_tag="ctg48_6"
                     /transl_table=11
                     /translation="MDKATQAYNDSSIQVLHGLEAVRKRPGMYIGSTDGRGLHHLVYEI
                     VDNSVDEALAGFGDEINVTIHADNSVTVQDHGRGMPTGMHPSGKPTIEVILTVLHAGGK
                     FNQNSYKTSGGLHGVGSSVVNALSESLTVRVVRDKRAFEEHFINGGHPDGSLQKLGKVN
                     EPNGTTITFKPDPTIFQTTVFSYDTLAERLRESAFLLKNITINLTDERTGKHDSYHYPD
                     GLVSFVKYLNEGKDALSQVINFEGKKDGIVVDFAGQYNDGYSENLISFVNNVRTGDGGT
                     HEIGLRSGMTRAFNEFARKVGLLKERDKNLEGSDVREGFAGILSVRIPEEILQFEGQTK
                     GKLGTPQARTVVDGIVYDKLSTFLMENGEESQELVRKAVKARDAREAARKARDDSRTGR
                     KRKKDQGLLSGKLTPAQTKNPKRNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNT
                     QKAKLQDIVKNEEINTMIYTIGAGVGADFDLQQANYDKIIIMTDADTDGAHIQILLLTF
                     FYRYMRPLIDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKGYTLTRF
                     KGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGDRVEPRREWIEHNVKF
                     DMDDDGSILETPTANHEKLQFGAKQIVKQLDKKGK"
     CDS             11538..12245
                     /locus_tag="ctg48_7"
                     /transl_table=11
                     /translation="MYVRFILLTYHSKVKNAKIVSSLRGGAHLILVLCFILAYFIGAIP
                     FGVVIGKLFYHTDIRKGGSHNIGTTNAYRMLGPVGGSIVLVLDILKGTLAASLPILFGI
                     EHHWLVLIVGLAAVFGHTFSIYIRFKGGKAVATSAGILLAYNPPFFVIAFAIWFSLILL
                     TSMVSVASTLGMVLITAWSLVYHDWLLTTVACGLLVVFLIKHRANFKRIKAGDENMVPF
                     GLGQYLRQHRGRS"
     CDS             complement(12327..13205)
                     /locus_tag="ctg48_8"
                     /transl_table=11
                     /translation="MVTIANDFLTVKISRHGAELTSIKDNLTGRERLWQADPAVWGRHA
                     PVLFPIVGALADNQYHYAGKTYHMGQHGFARDRDFTVLSATPFKASFVLKDDDKTRAMY
                     PFAFRLIITFALENNNLHVTYHVDNPDKSEPLFFSIGGHPGFKVPMTPDTQFSDYYLNF
                     KPRKSLVQIPLVAGEGIDYTHRTLAATDANLALTHETFDNDALIFALLGKTTFNLVSDK
                     TKHGVSVTMTDTPYLGVWSPYPTTGDFVCIEPWWGIADTIGSTGDLTRKLGINRLEPGT
                     AFEKGYMISIF"
     CDS             complement(13241..14650)
                     /locus_tag="ctg48_9"
                     /transl_table=11
                     /translation="MAEVQTPKQIVEKLDQYVIGQDDAKRAVAVALYNRYRRMQLSPKM
                     QEEITPKNLLMIGPTGVGKTEIARRLAKIVEAPFVKVEATKFTEVGYVGRDVESMVRDL
                     AETAVAMEEEKQFSKVRIRAEKEANKRLVKILVPAIRKEKNTNPMAEMMSMLQGMQNGK
                     MPAGDDADAGGEVTDDIRNKRLSVAEQLEKGLLEDHEITVAVNDEKKGGGMGDMYGQMG
                     IDLSDTIGALMPKKKVERTMTVKEAREIFIKEESDKLVNHADIYHDAIQSAENNGIIFI
                     DEIDKIAAGNKHNSGEVSREGVQRDILPIVEGSQINTKYGPINTDHILFIGSGAFAEAK
                     PSDLIAELQGRFPIRVELKDLTEKDFVRILTEPDNALIKQYIALIGADGVKITFTKEAV
                     DRIAEIATQVNHDTDNIGARRLATILEKLLEDVLYEGPDMAMGSVTVTQQYVDDKIGHI
                     AADSNMTRYIL"
     CDS             complement(14694..15218)
                     /locus_tag="ctg48_10"
                     /transl_table=11
                     /translation="MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVV
                     IGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHD
                     LLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDI
                     FTNHNVIVESF"
     CDS             complement(15466..16362)
                     /locus_tag="ctg48_11"
                     /transl_table=11
                     /translation="MKPIAAFQEYLEVERQYSPETVTAYLSDLQEFQAFLKANGGFTDF
                     RHVDDLDVQTYLTDLNKQDLARTSIARKISSLRSFYRYLTRIDVVKRNPFELVELKKQH
                     HHLPQFFYEAEIQELFKTVAGKTPLDQRNRALLEVLYGTGIRVSECAKLTLNQVDFNTA
                     LLLIHGKGNKDRYVPFGQYAQQALRTYLKDGRQVLMAKSQAQHRYVFVNQYGRPITSRG
                     IEYILDQLIKQTTLTANIHPHMLRHSFATHMLDHGADLRTVQELLGHASLSTTQIYTHV
                     TMAHLKNEYMKYYPKHN"
ORIGIN
        1 gggctagtgt tgatgaaaaa tgaacggtgg tgctggttca gccattgttc tgccatgtga
       61 agcagaattg aataaagttt tagctttatc caaaggtgag caaagatgtc agcaaacgcc
      121 tgttgttggt cagacaaatt ttagctggca taattctggc atgaattcgg ctattaaatg
      181 agttcacttc ggtcaatcat tcagcaaatt tattttggcc attggtcaac aaaataaatt
      241 tgctgaatgt tacgtgaccc tcaattgttg ttgagtcaat ttcaaactac acaactcaaa
      301 aaatcatcaa gcaactcgaa gccggctaac tgacgagaat ctcacaatat catgaagctt
      361 gaattgatat gcatttttct ggttttggct ggcatgacat tttcaatcaa acaaatgcat
      421 gcaactcagc gcaaacgcaa caacccaagt cataattgat tgccttggta aaaaatgcaa
      481 tcgccaccac caacattacg tccggaccac aaatttttga cagccatttg aaagagggga
      541 cacccagatt cgcagatcaa gtggcaaagc caattattta tattctagtt tacataatat
      601 atattatgcg aagtagcgtt tgaagagacg gcatcgtgcc attctcgcaa tatttacgtt
      661 ggcgattatt tgattcgcaa tttcatccag cacccgatag tcgcctcatt tttttaaccg
      721 ctgcttgcag ccaagtcttt aaaagcttct acaatcattg gaaatcattc gatatttttt
      781 tgcttgagtt ttttcgttaa gtcacttgcg acgaacaact atcaagttga attcccgaac
      841 tcgtctcaga atgcgtctct cagcatgcct caaaaccagc caaaacgacc catgacaact
      901 tgctgttgat tcgacccgcg aattgctaca caaatttcaa attcacgcat cacgaactgc
      961 tagccagctt tatatttaac agatttcgca aaaagatggc tagagacttt ttgcaaacaa
     1021 aaaagccgca actggctagc tgcgactttc cttagaacaa ttgtgtgcaa ttaaagatga
     1081 aagttaacct tcaaacgtgc tctgcattgg cggaacgacc tgctttttgc gggaaacaac
     1141 cccaggcaat gccaaacgcg cgtccttgtc gaactgttcg ttgaaagcac tagcgatttt
     1201 atcgcggtca gcaccgactg cgaaaccagt tgaattgctg tccaagatgt cagtggcaat
     1261 cagcaggaaa tcgtcgtagc ctttcgcctg cgcctctttg gtcatggcac tgatcaattc
     1321 gtcctgacgt gcgtaaatgt cgttcagatc gacggtattg acctgtccga tgcgaataga
     1381 cttgccgccc atggtgaaac tcttagcatc gccttcgata atgtccatat ctgacttggc
     1441 ggccaaatta gtacctgcct tcagcatggc aagaccatat gactgcaaat caattccggc
     1501 aatcttcgcc atttctggca aaatcttctt atccttgtcg gttgcggtcg gcgacttcaa
     1561 caacagcgtg tctgaaatca aaccagaagc catcaaacca gccaatgttg gcgaaatctt
     1621 gaagccatat tcttggaaca tctcaaaaat gacggtattg gtgctgccaa ccggttctgc
     1681 tcggtaaaac agcggcgctg ccgtgtggaa gttagcgatg cgatgatggt cgacaacaga
     1741 atcaatcgtc acgtcttcga tatcactgac actttgttga aattcgttgt gatcaaccaa
     1801 catgacatga tccgtctcgt tggctgccgt cttgataacc cgcggtgcct gaaccttgaa
     1861 gtgatcaaag acgaacttag tctcatcgtt cggttcgcct aatgctaccg cttcaacatc
     1921 cgtgttgcct gcctgtttct gaaattctgc ccagctcatg gcactcgtaa tcgcgtcggt
     1981 gtccgggttc tgatgcccaa aaatcaaagt cgtcatctta tctgatcgct cctcaactga
     2041 atagtttact tatcaagttt aacacggttt tcactgaccc gcgacaagta atctttttcc
     2101 ttcagataat cgtcaaaggt ctggaagaag ttcgagatcc gcggaatgtc agctttctct
     2161 ttgcgataaa caaaagaaat ctcaaagcga atggccggat caaacgcaat agcataggcc
     2221 ttgatttgat cagcgcgtgc ccgaacaaaa ctggttggca aggccgtgtt gacccctgac
     2281 aagttaacga attgggttaa ctgatatggc gtggtgaaat gtgcgaccac gtgcgggaaa
     2341 tcaaccattt gattcttgta cgcctcacgc agaagctgtc caaggaaata gtcgtcagga
     2401 taagttgccc aaggttcagc taaagtatct ttgaaatgga ttcgcttacg gttagccaag
     2461 gcgtcatcgt ggtgcaagaa cagcaattgt tcatcaataa ttttcttgct ggcgtatggt
     2521 ttccagttct taatggtctc atctggcaga ttcatgatag ccaaatcaat ctggttgttt
     2581 tccaaggatt cccaaatttc gtgacgggtc atcatccgta gcgttacttc aacttcagga
     2641 ttcagttgat agtaatgagc aatgaacgca ataaaggcgc tatcctcaat tgagcttaat
     2701 aacccaatat tgatttttcc gacggttgca ctggttgttt gttgaatttc gtcggttgtc
     2761 tggttcaaga tctcgtagat ctcatgggtt gactttaaca tggtctgacc agcgtcagat
     2821 aaatgcagtt tcttcccgac agaataaaac agcggtgccc ccaccgtccg ttccaatttc
     2881 ttgatctgct gtgttaaggc tggctgggta atgccaagca attgggcggc ttgggtgtag
     2941 ttcatggttt ctgccaattg cagaaaataa gttagtgtct ttgaggaaaa aatgcgctct
     3001 tgtttcgttt tcatagggcg gcttcccttt cgtttataat ttaataatat cgttcaacca
     3061 tcatcataag tggcaatgaa aaaaaacgca acgaatttgc cgcgttttta atcgttacgt
     3121 taagttctag ctaaaaattc agttgctcgc aactggtttc ggacgccagc tttgccatcc
     3181 ggtataatcc ttaacgtgca gcagattctc tgcattctta acgcgttcgg cagacggcgg
     3241 ttcgatgcct tcaagcgggt acgtaatgcc aagctcgtga tactttttaa cgcctaacgt
     3301 gtgatacggc agaatctcaa ctttttggac cacgtttttg tccaatgtcg caatatagtc
     3361 ccctaaccgt ttgagataag ggtcaaagtc agtgcgttcc gggaccagaa cgtggcgaat
     3421 ccacatgtca tcaccatgcg ccgacatata ctgcaccata tccaaaatat tctcattagg
     3481 aaaaccggtg agctttttat gctcggccga atcaatgtgt ttaatatcaa ctaatgagat
     3541 gtcagtaaca gccatcagct tttcaaactg gccaaaccac ggttggtcac gcgtgaaggg
     3601 gccacctgac gtatcgaggc aagtcgaaat tcccagtgcc ttagccttgg tgaagagttc
     3661 gagaatgaaa tcgatttgta ccaaactctc accgccactg caggtaatac ccccttggtc
     3721 accccagaat gctttatagc gctgggcatc cgccaaaatt tgatcggccg tcatttcttc
     3781 accaacccca atgttccagg tgtcagggtt gtgacaatac tggcaacgca tgcgacaccc
     3841 ttgcataaag acaacgaagc gaataccagg gccatcgacc gaaccaaaac tttcgaccga
     3901 gtgaacatac cctttgatcg ggccatcatg atcctgacca acttgttcta agatatttaa
     3961 tgggctttgt gactgatcga tgagtttcat cttattgcct ccactacaac atcatgtgtc
     4021 gttttcaatt gattttcatt tcattctgcc aaaaaacggc aacagcatcg ttgccgtctt
     4081 ttggcaaaac aggaatggct tcctgtcttg agttaagctg cttacatttc ttcgaagaag
     4141 gtccgagcaa tgacatcgtc ttgttgttcc ttggtcaaat ctgcgaagta gacgcagtag
     4201 ccagaaaccc gaacggtcaa tgttgggtat tcttctgggt gcttctgagc atcaatcagg
     4261 gtctccttgt tgaagacgtt gatgttcaaa tgcatgccgc tgttttccat atagccgtca
     4321 accatgtgaa ccaaggtatc cttacgagtt tcatcatcgt ggcccagtgt gttcggagta
     4381 accccaaacg tattactaat gccgtcagtt gcgtaatgat acggaatctt ggcggtggac
     4441 atcaaggatg ccaatgcgcc gttcttttct gcgccgtatg ccgggttggc acctggtgag
     4501 aatggttcgc ctttttgacg accgtttggt gttgtccctg tattcttacc ataaaccacg
     4561 ttggaggtaa tggtcaggac actggtactc aacttcgcgc cgcgatacag atgatgcgtg
     4621 ttcatcttgt tatagaaggt cttaaccaac cacttagcga tgtcatcagc gcgatcatcg
     4681 ttgttaccat agcgtggata gtcatcattg tcagcaacga agtcaactgc aacaccgttt
     4741 tcatcgcgaa ttgccttgac atgaccatac ttgattgcac tgatggaatc aaccgcgtgt
     4801 gacaggccgg aaatcccggt tgcgaaggtc cggttcagtt gggtatcctt caatgccagc
     4861 tgtgcagctt cataataata cttgtcatgc atatagtgaa tcacattcaa agcattgaca
     4921 tacgtgtcgg ccagccagtc catcatcttg tcgaacttat tcatgaattc tttgtaatca
     4981 atgtaatcgc tggtgatcgg tgcatattca ggccctactt gcgcttcctg aatttcatct
     5041 ttcccaccgt tgatcgcata cagaaccgtc ttagctaagt tagcacgggc accaaagtat
     5101 tgaacgccat cagcaattgg ttgtgccgag acacagcaag caataccgta gtaatcggta
     5161 ccccattcgt tgcgcatcag gtcatcattt tcatattgaa tggttgaact ttggatggat
     5221 acttcggttg catagcgttt gaagccttct ggcaagcgtt cgctccaaag caaggtgatg
     5281 tttggttctg gtgctgcgcc catgttgtcc aaagtcttca ggaaacggaa agccgtcttg
     5341 gtaacgtggt gacggccatc attgcccatt cctgccaatg acaaggttgc ccagattgga
     5401 tcgcctgaga acagtgagtt atattcttca gtccggatga aacgaaccat ccgcaatttc
     5461 ataaccaaat gatcaatcag ttcctgtgcc tgttcttcgt tcaatttgcc taagcgcata
     5521 tcgcgttgga tataagcatc aataaccgta tcgatccggc caacggacat tgcggcaccg
     5581 ttttgagtct taacagcagc cagatagcca aagtagatcc actgaacagc ttcttgcgca
     5641 ttagctgccg gacgcgagat gtcatagcca tattccttgg ccatcttctt catgtcgttt
     5701 aaggcacgat attgttcatt gatttcttca cgcagtttga ttacatcgtc agtcatttcg
     5761 ccgtcgccgg tcaagttata atccttgaac ttctcagcca ttaaacgatc gatcccgtaa
     5821 acagcgatcc gtgggaaatc agaaacaatc cggccacggc cgtatgcgtc tggcaagcca
     5881 gtcacgatct tgtaatggcg agcctttcgc atatcagggg tataagcatc aaagacacct
     5941 tggttatggg tcttacgata ttcattgaaa atcttgtgtt cttgaggatc tgtcttgaag
     6001 ccataagatt ccaatgcatc ttcagccatt cgaataccgc caaatggcat gaatgctcgt
     6061 ttgaatggct tgtcggtctg aacaccaaca atcttttcaa gatctttgtt caaataacca
     6121 gggccgtgtg aggtgatcgt agatggaata ttgttgtcag catccaaaac accgccattt
     6181 gcacgttctt gcttctttaa atttagaacc tgattgttca ggactgttgt cgcttcagtg
     6241 gggccagcaa ggaaactttc gtccccgtca tattggttca ggttatgctc gataaaatcg
     6301 cgcacattaa tttcttcttg ccagtcgccg ccgttaaagc cttcccaata attaggaact
     6361 ttggtttcgt caagctgttt catagttgtt tgcctcctaa agtggattac agatgtgaca
     6421 gttcttacaa acacagtata acacgccgcc aaatctatgc aagcgtttta ttgcccatat
     6481 aataggcgtt atattgtttt ttaagtgtgc ttcgtcgctt cttttcgccc atgatttcgg
     6541 cattttgtta aattgtgcac aactgatccg tcctataata atcaaaaacg ccaccatctg
     6601 tattagtaca gacggcggcg tcaatgatca ccatttattc gacttgatct gctggttctt
     6661 ctttggtttg aacaaaaact ggcttgccaa ggacatcagt gtcaatgaca aacgaaccat
     6721 tcgaatatcg gtcacctgct ggatgttgtg ccggattaag ggtcgttacc ttacccgtat
     6781 cggtcaaaac attcaggcgg gtagcgtcat cgactgacat catcgcgaca atccgatgcg
     6841 gatcacgctt aagctcacgc aagaccagta aaccacgacg ggcacgactc atttccccga
     6901 cctcgcttaa ggccatcttt ttgaaggcgc cacgttgggt caaaataccg accttagccg
     6961 tagttggatc cttcactaga atgaaattga caacctcatc gtctggcttt agatccatac
     7021 ttttaacgcc ggttgcccgg gcaccgacag ttgacacatc gcttaacggg aatgtcagtc
     7081 cgtaagcgtg gcggctgacc acaaagacat cctgttgctg atcagtcgtg aagtatgcat
     7141 tggtgacaat cgcggctggg tctttcagct tcatcgccat catcggctta ctcttgtacg
     7201 tccgttgcgg ctgcaaatca cttaaggcag tttgtttgat gtacccgtca cttgacccta
     7261 acacaaaact gccagcgcca tcgagttgat caaaagcaaa cactgccaag actttttcgt
     7321 cagtgccaag gccaactgtt tggcttaagt gttcgccggt gtctttccaa cgcgcatcac
     7381 taatttcatg cactggtcga taaatgacat ttccggcatt tgtcacgatg taaagatgct
     7441 gcaacgtact cagttcgcca gtgaaaatgg caagatcatt ggccttcaaa ccattgtcgg
     7501 ccggatcaac cgcctgataa ctgcgcagtg aactgcgttt aacgtagcca tcacgagaaa
     7561 cctgcaccat gacggtttca tcagccaccg tcaccgttgt cgccacttca agcgtttcaa
     7621 ttttggcttg aatgctgctg cgacgatcat ccccgtactc cttggcaatc cgcttcaact
     7681 cgccttcaat cacccgatcg cgggcagcgg ggcgggccaa aatatcttga tactcggcga
     7741 ttgctttcgc caattgtgct gcttctttct gtaaagccgt gatatcggta ttggtcaatc
     7801 gatacagctg caaggaaaca atcgcttccg cctgagcttc cgaaaaatca aacttcttga
     7861 ctaagttacg cttagcatct cctttatcct tggaagcacg aatcgcggcg atgacctgat
     7921 ccaaaatcga tagcattttg atcaagcctt cgacaatgtg ctgtcgagca gcggccttgt
     7981 tgaggtcaaa acgcgttcgc cgagtgacca catcgcgtcg atgttcgacg tatgcttcca
     8041 acatggcctt gagtcctagt aacttcggct gcatgtcggc aatagcgacc atgttaaagt
     8101 tgtatgcaat ttgcagatcg gtatttttaa ataaatagtt taagatgcca tgtgcatcgg
     8161 cttctttttt taattcgatg acaacgctaa gcccaaaacg gtcgctttcg tcacggactt
     8221 cggcaatacc gtccactttt ttgttgatgc gtaattcatc gattttttta atcatctgcg
     8281 ctttattgac atcatacggg atctcagtga ccacgatctt ctcacgaccg ccacgaatgg
     8341 tttcgatgtg tgtccgagaa cgaaccacga ttttaccgcg gccggtttcg taagcttgct
     8401 tgataccatc aagcccttga ataatcccac ctgttggaaa atcgggaccc ttgacgtatt
     8461 gcattaaagt atctaaatca gcagtgggat gcttcagcaa atataagacc gcattgatca
     8521 cttcgcgcaa gttatgcggc ggaatttcgg tcgcgtaacc tgcagagatg cccgttgcac
     8581 cattcaccag caaattcgga aatcctgcgg gcaacacagt tggctcctgt gccgtgtcat
     8641 caaagttcaa caccatatcg acggtttcct tatcgatatc ggccagcatt tccttgctga
     8701 ttttgcttaa acgcgcttcc gtatatcgca ttgcagctgg cggatcacca tccatggaac
     8761 cgttattccc gtgcatctga atcagtgggg cccgtaactt ccaatcctgg ctcagccgaa
     8821 ccatcgcttc ataaatggag ctgtcgccgt ggggatgata attacccatg acattcccga
     8881 cacttttagc cgacttgcgg aagcccttat catacgtatt gccatcttgg ttcatcgcaa
     8941 ataaaatgcg acgctgaacc ggtttgaggc cgtcacgcac atcaggcagc gcccgttctt
     9001 gaataatgta tttcgagtac cggccaaacc ggtcgcccat gacctcttct aaggtcagtt
     9061 cttgaatctg attggccaat ggcttttact ttcctttctt gtccagttgt ttgacgattt
     9121 gcttggcacc aaactgtaat ttttcgtgat tagcagtcgg ggtttccaaa atactgccgt
     9181 cgtcatccat atcaaacttg acgttatgct caatccattc acgacgcggc tcaacgcgat
     9241 cacccatcaa agtggtcacg cgtcgttccg ccagctgagc atcgtcaatc cgaacccgga
     9301 tcaaagtccg cgtctcagga ttcatagtcg tttcccaaag ctggtcggca ttcatttccc
     9361 caagtccttt aaatcgggtc aatgtgtaac ccttgcccat ggccttggtt tctttggcca
     9421 actcttcatc ggtccaagca taactgatct tggttttagc accagcgcct ttttgcagcc
     9481 gatacaatgg tggcaaagca atgtaaattc ggcctgcgtc aatcagcggc cgcatgtagc
     9541 gataaaagaa ggttagtagc aaaatctgaa tatgcgcgcc atcagtatcc gcatcagtca
     9601 taataatgat tttgtcgtag ttggcctgct gcagatcaaa atccgcaccg acaccagcgc
     9661 cgatggtgta aatcatcgta ttgatttctt cgtttttaac gatgtcctgt aacttggcct
     9721 tctgggtatt cagtactttc cctcgcaatg gcaagatcgc ctgaaacttt cggtctcggc
     9781 cttgtttagc tgaaccaccg gcagaatccc cttcgacgag atacaattcg ttacgcttag
     9841 ggttcttggt ttgcgccggg gtcaatttac cggaaagcaa accttggtcc ttcttgcgct
     9901 tgcgtcccgt ccggctatcg tcgcgcgctt ttcgagccgc ttcccgcgca tcacgggctt
     9961 tgacggcttt acgaaccaac tcttgcgact cttcaccgtt ttccatcaaa aaagttgaca
    10021 gcttgtcata gacaatccca tcgaccacag tgcgggcttg cggcgtacca agcttgccct
    10081 ttgtctggcc ctcaaattgc aaaatttctt ctggaatgcg gacacttaaa atacctgcaa
    10141 aaccttcacg cacatcactg ccttcaaggt tcttgtcgcg ttccttcagc aagccgactt
    10201 ttcgggcaaa ttcattgaat gctcgcgtca tgccgctgcg caagccaatt tcatgcgtcc
    10261 cgccatcacc agtgcgaacg ttattaacaa acgaaatcag attttcagaa tagccatcgt
    10321 tatattggcc ggcaaaatca accacgatac cgtccttttt gccttcaaaa ttaataacct
    10381 gcgacaatgc atctttgcct tcgttgaggt atttaacaaa gctgaccaaa ccatcaggat
    10441 agtgataact gtcgtgctta ccggtgcgtt catccgtcag attaatcgtg atatttttca
    10501 gtagaaaggc tgattcgcgt aaccgttcgg ccaaggtatc ataactgaaa acagtggttt
    10561 gaaaaatagt cggatccggc ttaaacgtga tggtcgtgcc attcggttcg ttgactttgc
    10621 ccaacttctg caaactgcca tcaggatgac cgccattgat gaaatgttct tcaaatgcgc
    10681 gcttatcccg cacaactcgc acggttaatg attccgatag ggcattgacg acgcttgagc
    10741 caaccccatg caaaccacca gaagttttgt aactattttg gttaaacttt ccgccggcat
    10801 gtagcacggt taaaatgact tcaatcgtcg gtttgccgct cgggtgcatc cccgttggca
    10861 tcccgcgacc atgatcctgt acggtcacag agttatcggc gtgaatcgtc acattgatct
    10921 catccccaaa ccccgcgagc gcttcatcga cagaattgtc cacgatttca tagaccaagt
    10981 gatgcaaacc gcggccatcg gtggatccaa tatacatccc tggacgcttc cgcacagctt
    11041 ccaagccatg cagcacctga atggatgaat cattatatgc ttgcgttgct ttatccatag
    11101 taaactccct tttttgaaca actaagttat agaatacacc acgcgttgag atttcagaaa
    11161 taaaaaataa gagcgcgagc aggggcggtt agcaaccgga gtgtaagcgg ccttggacgt
    11221 gatggtcggg ctttgaccat tgcggccaag gtccttacac gcaggttgct gcgactgtga
    11281 gcgcgtttag gcatcaacac catcaacagc agacctcacc gtattgctct caggactcct
    11341 gttttctcct caaaatcgac ccagctggct aataccatca ttgttcattt aaattttatt
    11401 agccgtgtca atgtcccaaa gctcagcaga aaaccgcact tccctaagca tggcacataa
    11461 ctatgacttc ttgacgtgaa attcatcgcc cgctggcacc aaatcgcgcc acaacccgct
    11521 tcacaggttt tattcgaatg tacgttcgtt ttattctact gacgtatcac tcaaaagtca
    11581 aaaatgctaa aatagtttct agtttgagag gaggggcaca tttgatactt gtgctttgtt
    11641 ttatactcgc gtatttcata ggcgccatcc cgtttggtgt ggtcattggt aaactctttt
    11701 atcacacgga tatccgcaaa ggcgggagtc acaatattgg caccacaaat gcttatcgca
    11761 tgttagggcc agtcggcggc tcaattgtct tggtgctgga tatcttaaaa ggcacgttgg
    11821 ctgccagctt acccattctc tttggcatcg agcatcattg gctggtgctg atcgtgggtt
    11881 tagcggccgt attcggtcat acattttcga tctacattcg ctttaaaggc ggtaaggcgg
    11941 tggcaactag cgctggcatt ttacttgcat ataatccgcc attttttgtc attgcatttg
    12001 ccatctggtt cagtttgatc ttgctaacgt ccatggtcag cgttgccagc acactgggta
    12061 tggtgttgat cacagcttgg tcgcttgttt accatgattg gttgctgaca actgttgcct
    12121 gcgggctgct ggttgtcttt ttgatcaaac atcgggcaaa cttcaaacgc atcaaggccg
    12181 gagatgaaaa tatggtgccc tttggcttag gccaatatct tcgtcaacac cggggccgct
    12241 cctagtcacc ttttgatggc aaccaaaaag acatccgaaa ctggatgtct ttttttcatg
    12301 tacctaatcg acaaactgat gacaccttag aaaatgctga tcatgtaacc cttctcaaat
    12361 gccgtgccag gttcaagtcg attaatcccg agtttgcgcg tcaggtcgcc agtgcttcca
    12421 atcgtgtcgg cgatgcccca ccaaggttcg atgcagacaa agtcgccagt ggttggatac
    12481 ggactccaaa cgcccagata tggggtatcg gtcatggtaa cactgacacc atgtttcgtc
    12541 ttgtcagaaa ccaagttgaa ggttgtcttg ccaagcaacg cgaaaattaa agcatcatta
    12601 tcaaatgttt cgtgcgttaa ggccaaattg gcatcagttg cagccaaggt ccggtgcgtg
    12661 taatcaatgc cttcaccagc aaccaatgga atctgaacaa gcgacttacg cggtttgaag
    12721 ttcaaataat aatcggagaa ttgagtatcc ggcgtcattg ggaccttgaa gcccggatgg
    12781 ccgccgatgc taaagaacag tggctcactt ttgtccggat tgtcaacgtg atacgtgaca
    12841 tgtagattgt tattttctag tgcaaacgtg atgattaaac gaaaagcgaa cgggtacatc
    12901 gcccgcgttt tgtcatcatc cttcagaacg aagctcgctt taaacggtgt cgcagagagc
    12961 accgtgaaat cacgatcacg ggcgaaaccg tgctggccca tgtggtaagt cttgcctgcg
    13021 taatgatatt gattgtcagc cagcgcccca acaatcggga acaagaccgg ggcgtggcga
    13081 ccccacaccg caggatctgc ttgccacaga cgctccctgc ctgtcaggtt atctttgata
    13141 ctggtcagtt cagcaccatg ccgactgatt ttaactgtca aaaagtcatt tgcaatcgtt
    13201 accatacatc ctcatccttt acctacaaca ttattgttaa ctacaaaata taccgcgtca
    13261 tgtttgaatc agccgcaata tggccaatct tgtcatccac atattgctgg gtgacggtca
    13321 cactgcccat cgccatatct ggaccttcat aaagtacgtc ttcaagcagt ttttcaagaa
    13381 tggtcgccag tcgccgcgct ccaatattat cagtgtcgtg gttgacctga gtcgcaatct
    13441 ctgcaattcg atcaaccgct tccttcgtga aggtaatctt cacgccatct gcaccaatca
    13501 aggcgatata ctgcttgatc aaagcattgt ctggctcggt caagatccgc acaaagtctt
    13561 tttcggttaa gtccttcaat tcaacccgaa ttggaaaacg cccttgaagt tcagcaatca
    13621 aatcactagg cttagcctcg gcaaacgcac ctgagccaat gaacaagatg tgatccgtat
    13681 tgataggacc atacttagtg ttaatctgcg atccttctac aatcggtaaa atatctcgct
    13741 gcacaccttc acgcgaaact tcgccgctat tatgcttgtt tcccgcagca attttatcga
    13801 tttcgtcgat gaaaatgatc ccgttattct cggcactttg aatggcgtcg tgataaatgt
    13861 cggcatgatt gaccagtttg tcagattcct ctttgatgaa gatttcgcga gcttctttga
    13921 cggtcatggt ccgctcaacc tttttcttag gcattaaagc gccaatggtg tcgcttagat
    13981 caatgcccat ctgaccgtac atgtcaccca tgccaccgcc ttttttctca tcattgacag
    14041 caacagtgat ttcatgatct tcaagtaatc ctttttccag ttgctctgcc acactcaaac
    14101 gcttattgcg aatatcatcg gtcacttcgc cgcctgcatc tgcatcatcg ccagctggca
    14161 ttttgccatt ttgcatccct tgcaacatgc tcatcatctc ggccatcgga ttggtattct
    14221 tttccttacg aatggccggc actaaaattt taaccaaacg cttattagct tctttttcgg
    14281 cacgtatgcg aacctttgaa aattgcttct cttcttccat ggcaacggca gtttcggcaa
    14341 gatctcggac catggattcg acgtcacggc caacgtagcc aacttccgta aacttagtcg
    14401 cttccacctt cacaaatggc gcctcaacta ttttcgccag tcgtcgtgca atttcggttt
    14461 tcccgacacc ggttggtccg atcataagta agtttttcgg ggtaatctct tcttgcattt
    14521 ttggcgataa ttgcattcgc cgataacggt tatacaaggc aaccgcgacg gcccgttttg
    14581 catcatcttg tccaatgaca tattgatcga gtttttcaac gatctgtttt ggggtttgta
    14641 cttctgccat cataagcctc ctgtaggtca atgtaattgc cgacggttac aaactaaaag
    14701 ctttcgacaa taacattgtg gtttgtgaaa atatcgatat tccctgcgat attcactgct
    14761 tctttggcaa tgtcagctgg tgtcatatct ggggcatgcc gcagcatcgc gattgccgcg
    14821 gcttgcgcaa agttgccgcc ggagccgatc gctaccacgt cttcatctgg atctatcact
    14881 tcgccagatc cggatacgag taacaggtca tgctcatcca tcacgatcat catggcctca
    14941 agtttctgca aggtcggatc cttgcgccaa tcttgagcca gcgcaactgc ggaacgtcgc
    15001 aagttgcccg cataatgctc cagcttcttt tcaaaccagt cttgcagggt gaaagcatct
    15061 gccaccccgc cggcaaaccc gatgacgact tgatcatgat agatccggcg aactttctgc
    15121 gcgttgcctt tcatgatgac cttttcgcca agggttacct gaccgtcacc ggccaaagcg
    15181 gtcacaccat cttttcttac tgctgcaatt gttgtcatag tcatgctcct ttttaagtga
    15241 gcgcgagcag aagcgcttag aaaccggagc ataagtgggc cggaagccta aatggctgaa
    15301 ttttggctat ttcggcttcc aggtcattat gtgtaggttt ctgcgactgc gagcgcgtta
    15361 tctgcgtatc tcgtcggata aaaacagcta aagtagcgat taatctgtta tcgccaatgt
    15421 tcttagctta aaaaactcag actgcttttg catcatgctt tagtcttaat tatgtttcgg
    15481 ataatatttc atatactcat tttttaaatg tgccatggtg acatgcgtgt agatttgtgt
    15541 ggttgataaa cttgcatgac ccagtagctc ttgaacagtt cgcaggtcag caccatgatc
    15601 cagcatatgg gttgcaaaac tatgccgcag catgtgggga tgaatgttag ctgtcagcgt
    15661 cgtctgcttg atgagctgat ccaaaatata ttcaatgcca cgcgaggtaa tcggacgtcc
    15721 atactggttc acaaatacat atcgatgctg tgcctgactt ttagccatca agacttgtcg
    15781 gccatctttt aaataagttc ggagtgcttg ctgagcgtac tgtccaaagg gcacatacct
    15841 atctttgttg cctttaccat gaatcaacag taatgccgta ttgaaatcga cctgattcaa
    15901 tgtcagcttg gcacactcgg aaactcgaat accggtgcca tacaaaactt ccaacaaagc
    15961 gcgattacgt tgatccagcg gggttttgcc agcaactgtc ttgaacagtt cctgaatctc
    16021 ggcttcatag aaaaattgtg gtaaatgatg atgctgcttt tttaattcaa ccagctcaaa
    16081 tgggttgcgt ttgacgacat caattcgtgt caaataacgg taaaagcttc gcaaactgct
    16141 gatttttcgg gcaatcgatg tccgtgccaa atcctgtttg ttaagatcag tcaaataagt
    16201 ttgaacgtct aaatcatcca catgccgaaa gtcagtaaac ccgccgttgg ccttgagaaa
    16261 cgcctgaaat tcttgaagat cactcaaata agccgtcact gtttccggtg aatactgccg
    16321 ttcaacttca agatactctt gaaacgctgc aattggcttc attgaatccc tccgataata
    16381 cat
//
