LOCUS       gnlProkkaMGBOLGFJ_6    16213 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MGBOLGFJ_6.
ACCESSION   gnlProkkaMGBOLGFJ_6
VERSION     gnlProkkaMGBOLGFJ_6
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 19:17:22
            Original ID  :: gnl|Prokka|MGBOLGFJ_6
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 66431
            Orig. end    :: 82644
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16213
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10736]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10736
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..16213
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16213
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             791..1378
                     /locus_tag="ctg6_52"
                     /transl_table=11
                     /translation="MSKRVITINRMLGSNGRLIGKALAEELGFAFYDKELIDIAAQKEN
                     IPFDLLAKVDEKRGSQWRFPIDHELQMDSDFHFVPMNDVLFDLQRKIILDAAEKEDCVI
                     VGRCANHILDNKCLSVFIHAPFEYRVQTVIERTGREEKSAQKLVKKVDKERRTYYEYFT
                     DKKWKDISQYHLAFDSSKFEQDKIIQMIKMAL"
     CDS             complement(1458..2558)
                     /locus_tag="ctg6_53"
                     /transl_table=11
                     /translation="MNKNEIYIKSGTNYKEMTKELLAQCGLASVISDKKMQIGIKPNLV
                     SPSEASWGATTHPEIVAGIIEYLQENGYGNIAILEGSWVGDKTIEAYEVCGYRELTEKY
                     QVPFWDMQKDKGIERDCRGMKLNVCERAANIDFLINVPVLKGHCQTKITCALKNMKGLI
                     PNTEKRHFHAMGLHEPIAHLNAGLHQDFVVVDNICGDLDFEDGGNPVVMNRIWAGTDPV
                     LIDSYVCQIMHYTTKDVPYIELAEKLGVGSTDLKNSHIVYCEENARKELPKSRKVVELQ
                     DAVEEVESCSACYGYLIPALEMLKNDGLFEKLDTKICIGQGYRGKTGKLGVGACTCKFE
                     HNVKGCPPTENQIYDFLKQYILGENK"
     CDS             complement(2656..3198)
                     /locus_tag="ctg6_54"
                     /transl_table=11
                     /translation="MATLQQLDMNILLWIQEHLRVDALTPFWRAVTFLGNGGWFWIVLC
                     VLLICFGKTRKTGVTAALSLLSGFLITNLLIKNAVARPRPFDTYTQIIPLITRPKDYSF
                     PSGHTCASFAVALVCLRMLSGKWGILPVVLAGMIAFSRLYLGVHYPGDVLAGFLVALLT
                     SSVACRLMRRTFSPQKS"
     CDS             3446..4828
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 214.6; E-value: 3.6e-65)"
                     /gene_kind="transport"
                     /locus_tag="ctg6_55"
                     /transl_table=11
                     /translation="MINTLSAGKDNFYRQMLKLTIPIIIQNLLSAAVNSADVIMLNYVG
                     QSAISAVSLAANYSNILFMVYYGLGTGASLLCAQYFGKNNMQAIHAIEGIALRFSIIIS
                     GIVALIAFTAPQLMMKIFTSDQELISIGSSYLRIMGITYLCWGISEIYLAILRSIGRVT
                     ISMALNMLAFILNIILNATFIFGLFGAPKLGATGVAIATAASRLIELAACVIVSFLSKD
                     VKLNLTFMFIRSKVLFGDFVRLSLPALGNDVSWSVAFSMYSVILGHLGTDAVAANSLVT
                     VVRNIGSVFCFAIASAGTILLGNVMGKGDLEKSKVYASRMLKMTIIAGAIGGVIVFAIT
                     PLVLRFASLSDGAMHYLKYMLLINTYYIMGSAVNTALIAGVFRAGGDTKFGLICDTIDM
                     WVYAVPLGFFAAFVLKLPVLWVYFLLCTDEFVKWPWVFHHYRQGKWAQNITREDLFEQK
                     AS"
     CDS             complement(4986..5417)
                     /locus_tag="ctg6_56"
                     /transl_table=11
                     /translation="MRKRTTSRAKETIKEATTKATEAVKETVEKTTVKASEVIEEAKDA
                     AADIAKAPVVEEAKETVKKAVKEVAKNIDIKKFAETTIELPGFAVTMSSIEEAIKKDIK
                     DKGIEGKEISVYVNVEQKAAYYTVDGQGSDDYRIDLNTL"
     CDS             complement(5445..5831)
                     /locus_tag="ctg6_57"
                     /transl_table=11
                     /translation="MGISQIQSLQISRASIGSVVDLDALTKISRQLDVSMGSMMGMVNG
                     FAIMIYMVLIYLLSKIIIEKNAQSISMVKILGYTNGEISKLYIMSTSLVVVFCLLLSLP
                     LETVIMKVLFREMMLSSISGWITL"
     CDS             complement(5770..5910)
                     /locus_tag="ctg6_58"
                     /transl_table=11
                     /translation="MIIRLPCVFMPRSELNDIFDLGEDYYSGYFSDTELTDIKSQYRIC
                     S"
     CDS             complement(6124..6921)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 85; E-value: 8.5e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg6_59"
                     /transl_table=11
                     /translation="MSRTRRNFSAKFKSELVIELLKGEKDLNTIASENNIQPNLLRNWK
                     KEFLDKASVVFDDTREDNLKEKLALERKEKAEYAKKVGQLTMQVDWLKKNLKKHLDLTT
                     RVNLVQNFLKTKELPVKTGAALLDINRTSVYYKGTPISQEELDCKSIIDRLHTDNPAWG
                     ARQLSAQLKKRGHQVGRRKTRRYMNEMGIDPIYPKMNLSKRMQQAKVCPYLLRNAVIDR
                     PNQAWSIDITYIAIKHGFLYLTAVIDWYSIVVQLSRQKSKLFM"
     CDS             complement(7186..7461)
                     /locus_tag="ctg6_60"
                     /transl_table=11
                     /translation="MTFSPFLCLIEEIMQCFFVNGAKIVFNSFRYNKSLKPKKERNGNE
                     TGKSCLHSPLPGKGFVIIIEPVINEEIKECRMNFNRNQNRKRKKKT"
     CDS             complement(7519..7698)
                     /locus_tag="ctg6_61"
                     /transl_table=11
                     /translation="MATSSILTELVIEDPKKAEAFINALEMSSQDPVCSPSAPSIPILY
                     SVEEIRRFLERKNK"
     CDS             complement(7794..8426)
                     /locus_tag="ctg6_62"
                     /transl_table=11
                     /translation="MGKQQDREKIVQEIKVAADLYRKHLVGKRFLYVFEGRYIEVLYKA
                     ANFRHLTGVATNLSAKKFYSYAAKKMLQASQIFFTPQHPFSLCKRKIKHIGQIAMLAGS
                     EGFMLEEIVTDTRTYKFGTTDLNFTLCLNKEYDDKGQQKGDCFVVESLRDEDCFSKSRT
                     AYTVTHIFSAPNDAKKYTNLLFLDENATVDGLPDEIKNMLDQTLLHK"
     CDS             complement(8782..9390)
                     /locus_tag="ctg6_63"
                     /transl_table=11
                     /translation="MNVYEEIDQETMMLLLDSLCKRTVEGKQIWENMEYNPISFLQKDI
                     YEKEGTCISQMFEATTVFNNIEYELELSESIELPSGKGDIFGTVSYETEDGKENTYDFS
                     LSFDVEKYDDANAEELQGIFGNSIIVQFTDAIVGVFENSDAVAEGFAYARYYHQTGIDS
                     EWETNPLVKLGEKLMQERAMRDFHKIVLDTDYRRSLLKQ"
     CDS             complement(9578..9907)
                     /locus_tag="ctg6_64"
                     /transl_table=11
                     /translation="MQTVFPEYKSEIVLGNGKFQLDPMSYTVIYEGKEISLAPREFEVL
                     YLLAQRPNWVIPKKNIYCSVWESNYYDDQIPYKTVEHVVWKIRKKMGHDIIETLINVGY
                     RLKKM"
     CDS             complement(10001..10582)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_65"
                     /sec_met_domain="AgrB (E-value: 8.4e-35, bitscore: 112.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLSEKITRYVIDAGAVSEELYAVYQYGFQIGLEMLICLFVCMS
                     IAIYLHTIPEFLVSTGVFMFLRTYAGGVHLNSFKACFTCSVAVQVMILQINNKYPLELF
                     VAWGIILVSSICIWKLSPVENINHELEREEKEHCRKVTGKILGAILIATGCCTALGMKK
                     YISLIALTALTVFISQCIGIIKYKVEKEKN"
     CDS             complement(10587..10736)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_66"
                     /sec_met_domain="TIGR04223 (E-value: 3.9e-17, bitscore:
                     54.3, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSKNLKNQPAKVLANLSLKLGKMSADSACCYIYHQPKMPEALKK
                     MKKL"
     CDS             complement(10878..11291)
                     /locus_tag="ctg6_67"
                     /transl_table=11
                     /translation="MDSVKILLFSDDEKLYNSTERIIGKKHQLKWCTYQQLENNRYPTA
                     DVVIFHFTKEIIERERAFAAIIKIKGSLGHLTPILAISEGGSIQDIFSILKAGAYDYIE
                     TIDNTRKYKKKIENLILWNWYIKKHTSAKKRQC"
     CDS             complement(11390..12700)
                     /locus_tag="ctg6_68"
                     /transl_table=11
                     /translation="MWTNSVLMCGIDILLCLWAVYLFFFYFDIFFARKRKRYLSVIGIT
                     LFVIWQFGITTIISFPAYINIAVTIMFTFLAVMMTYEGRWWNKGVFVITFNAIWMLMET
                     LCNYILITYCPQYAAVRQVGSFVSKIFFNAVILALKKVFTDDDIKELPVRYSILLVLIP
                     TGSIYIMNNIFMLGFANNNGRTRINSTFTVLILLGMNILIFYVYMKLADDLRLRRMAAV
                     YEQQLELCERHQQERELSMLQLRDIKHNMKNNLISILAYAENKEYEKMTGFIEEIMGEG
                     GMVIASISNSGNIVIDSLIGYWYVTAQNKRIIFKTDICIPMIMPFKGADLSLILGNLLE
                     NAVEAAEKVEENRYINVKMKFDKNNLLLFVDNSYKGKLLKTRDNRLKSTKSDAENHGVG
                     LASVYRAVAKYHGSVVIEDSEPGKFKIRIVLYSNVQE"
     CDS             complement(12687..13415)
                     /locus_tag="ctg6_69"
                     /transl_table=11
                     /translation="MLNIAICDDDIQITGKIERLLQDIAKRNFVDTEIEVFWNGKSLAD
                     AIAAGERYDVIYLDIEMDKEDGISAARRIRTYDKNVRIIYVTSHESYMRESFEVRPFQF
                     LVKPVTDKIMEKCFKSVYEDINSEDFYFRYSYQRMNHKVPIKDILYFESNKRKIFIVTE
                     QEILELYGKLNEIEETLKTCKISFLRVHQSFLVNYKHISGQSYDSVVMDNGQKISISED
                     RRKIISEQYCSMEDTFYVDE"
     CDS             complement(13543..13770)
                     /locus_tag="ctg6_70"
                     /transl_table=11
                     /translation="MARPRKMISLEEQIKKQEETVLKVKEKYDSEMMKLKDLHAKRNEE
                     KKKELLKAVENSTKTYEEIMAFICSDGGIN"
     CDS             complement(13774..14808)
                     /locus_tag="ctg6_71"
                     /transl_table=11
                     /translation="MKKQIRMITYLPLFYEQYPGSIVDISQLQYMLKKAEGYGYKKVGF
                     ILDRGYFGRENIRYMDECGYDFVIMVKGMSESVRRMILENKGEFENIRKYNIRKYKTFG
                     KTIRKKLYISDEKERYFHIYYSDQKACVEHEQIEAKIDRMTKYLKGLKGEKATVGDGYK
                     KYFKLEIYKDDGTIICARERTEVIQEEIDLCGYFVIVTSKQMTAEEALELYKSRDVSEK
                     LFRGDKSYLGNRSLRVQSDEAANAKIFVEFVALIVRSRMYVLLKDEMEKLDKKPNYMTV
                     PAAIRELEKIELVRQTDGKYCMDHAVTATQKIILKAFDMDADQIQDKAVGLSRLLEKYA
                     EEGK"
     CDS             14859..15200
                     /locus_tag="ctg6_72"
                     /transl_table=11
                     /translation="MNKEEKAKLWADRIQQYKTSGQTCKQWCAENDIPLSTMGYWTRRL
                     AKEDPASEPEQDLVFARLPSEREAARKLLSEETAPVRIFVSDSIRIEISDSCRPELMES
                     ILGFLQCHA"
     CDS             15700..15891
                     /locus_tag="ctg6_73"
                     /transl_table=11
                     /translation="MEPIFTDKQLNNMSREDLISLMKIVQEQTKKKDTEIQLLKDKQKE
                     LEFLNAMLSDRLTPMWST"
ORIGIN
        1 gtattcagag cttcatttgt ctccaggtca tgaagcggag tcatacatcc gatgacaaat
       61 tcgtcatcat tctccgaaat cgcatccagc cccagaccgg aaagatcaat cgctgtggat
      121 attgctctgt tgcccatttt catccagacc attcccccaa gaatacgggc tgttttcttc
      181 cggttcagtt cataagcttc cgccagactg tttaccttta catagctttt gattttcagc
      241 attatgtatc gtatcccttt cttacatact tttcatatct cttgtaatat tttgactcgg
      301 atctgtcgtc agacagccaa tttaatataa taccatagct taaagaaaaa atctataaat
      361 atcctctatt tcattctatt tcataaataa atttttcact gtaccggcgt cttctgactc
      421 ggcagtaatc ctggtcaggc ggacaatatc atccgctttg ctacttgctg taaatattac
      481 tctaattcta gcatatgaca gccaaaagtg tctattgata aaactatcca aaaaaaactt
      541 ttcaaaatat tatcggatta actgtatcat ttgtttcatt gcgaatcgtt ttttgtgcac
      601 tgtacctaaa tattttcgta atatatttgg ttttttatat attttactgg attttttcaa
      661 gtatcaatgt tataatgttc acaaataaaa gacttatcac tgttaattgc agataacagg
      721 tacaatttgc gaatatccgc ctgaatctat atcgttcaat aacagagatg tcataaagga
      781 gggtttgatt atgagtaaac gcgtgattac aataaacagg atgctcggca gtaatggccg
      841 cctgatcggt aaagctctgg cagaagagct tggatttgct ttttatgaca aagagctgat
      901 cgatattgca gctcagaaag agaatattcc ttttgatctg cttgccaagg ttgatgagaa
      961 acgtggcagc cagtggcgtt ttcccattga ccatgaactt cagatggaca gcgattttca
     1021 ctttgttccc atgaatgatg tgctctttga tcttcagcga aagattattc tggatgctgc
     1081 tgagaaagaa gattgtgtga tcgttggccg atgcgccaat cacatcctcg acaataaatg
     1141 cctgagcgta tttatccatg caccatttga gtatcgtgta cagactgtca tcgagcgtac
     1201 gggacgggaa gaaaaaagtg cacagaagct ggttaagaaa gtggataaag aacggcgtac
     1261 ttattatgag tactttacag ataagaaatg gaaagatatt tcccagtatc atctggcatt
     1321 tgacagcagt aaatttgagc aggataaaat tatacagatg ataaagatgg cattgtaaaa
     1381 tcaaacaggg ttccagattc aaaagtctta tcatgcaggc acgaacgact ttttgaacct
     1441 gggaccctga tatcatatta tttattttct cccagaatat actgcttcag gaaatcataa
     1501 atctgattct ctgttggagg acatcccttt acgttatgtt caaatttaca ggtgcatgca
     1561 cctacaccca gttttcctgt ttttccgcgg tatccctggc cgatgcagat tttcgtgtcc
     1621 agtttctcga aaaggccgtc atttttaagc atttccagag ccgggatgag ataaccatag
     1681 caggcactgc aggattctac ttcttctact gcatcctgaa gttctaccac ttttcttgat
     1741 ttcggaagtt ctttgcgggc attttcctca cagtatacga tgtgggaatt tttcagatca
     1801 gtacttccaa ccccaagctt ctctgccagt tcaatatacg gtacatcttt cgttgtataa
     1861 tgcataatct gacatacata agaatcgatc agtaccggat ccgtccccgc ccagatacgg
     1921 ttcatcacta ccggatttcc gccatcctcg aaatccagat ccccgcaaat gttatcaacc
     1981 acgacaaaat cctgatggag ccccgcattc agatgtgcaa tcggttcatg cagtcccatc
     2041 gcatgaaaat gacgcttctc tgtattgggg atcaatcctt tcatattttt caatgcacat
     2101 gtgatctttg tctgacaatg gcctttcaat accggaacat tgatcagaaa atcaatattt
     2161 gccgcacgtt cacagacatt cagtttcatc cccctgcaat ctctttcaat ccccttgtct
     2221 ttctgcatat cccaaaaagg cacctgatat ttttccgtta gttcacgata tccgcacact
     2281 tcgtatgctt ctatggtctt atctcccacc caggagcctt ccagaatggc aatatttcca
     2341 tatccgtttt cctgcagata ctcaataatt cccgccacaa tttccggatg tgtggtagct
     2401 ccccatgaag cctcggaagg tgatacaaga ttaggcttga taccaatctg catcttttta
     2461 tctgaaatta cagacgccag gccgcactgt gccagcagtt cttttgtcat ttctttgtaa
     2521 ttggttccgc tctttatata gatttcattt ttgttcatta caagattatc ctttacactt
     2581 tacattcgaa tatttttctg ctgatttttg catatctttt ttgtatttcc tcccggaagt
     2641 tttcttctga accggtcagc ttttctgagg tgaaaatgtt ctccgcatca gcctgcatgc
     2701 cactgaactt gtgagcaatg ccaccagaaa tcctgccaga acatcccccg gataatgtac
     2761 gcccagatag agtctggaaa aagcaatcat tccggccaga acaacaggca aaattcccca
     2821 tttcccggac agcatccgca gacaaaccag tgcaacggca aaggaagcgc aggtatggcc
     2881 ggatggaaat gaatagtctt tcggtctggt gatcagcgga atgatctgtg tataagtatc
     2941 aaaaggtctt ggacgggcta ctgcattttt tatcagcaga tttgtgatca gaaaccctga
     3001 cagcagcgag agtgccgctg tcactcctgt tttgcgtgtt ttcccgaaac agatcagaag
     3061 cacacataat acgatccaga accatcctcc gtttccgagg aaggtgactg ctctccagaa
     3121 cggagtcagg gcatccaccc ttaaatgttc ctggatccac agtaaaatat tcatatctaa
     3181 ttgctgtaat gtcgccataa acttctccca ttatattttt tatcagtcac agtatgtatt
     3241 cctctcaaaa tacatacgaa ttatatcagt ccgacttctt ttgtgcaagg tattataagc
     3301 aaagttgatt tgtttaagga ctcaaaagtc aaaataacgt agaaatcagt caaaataccg
     3361 atagcgtttt tctgccggaa ggattatgct gaaagcagac taataaaact gcctgatcgg
     3421 gcaaatactt atttcggggg taaatatgat aaacacatta tcggccggta aggataattt
     3481 ttaccggcag atgcttaaac tgacgattcc gattattatc cagaatctgc tcagtgcagc
     3541 ggttaactcc gcagatgtaa ttatgcttaa ttatgtggga cagtctgcga tttctgcggt
     3601 gtctctggct gccaattact ccaatatcct gtttatggta tattatggac ttggtacagg
     3661 cgcatctctt ctgtgtgcgc agtatttcgg aaaaaataat atgcaggcta ttcatgcgat
     3721 cgagggaatt gccctccgct tttccatcat aatctcggga atcgtagcac tgatcgcatt
     3781 tactgctcct cagcttatga tgaagatttt tacttctgat caggaactga tctctatcgg
     3841 ttcttcttat cttaggatta tgggaattac atatctctgc tggggaattt cagagattta
     3901 tctggcgatt ttgcgcagta tcggacgtgt aacgatcagt atggcattga atatgctggc
     3961 ttttatattg aatattatcc tgaatgccac ttttatcttc gggcttttcg gcgcaccgaa
     4021 gctgggggct acaggtgttg ccattgcaac tgctgcttcc agactgatcg aactggcagc
     4081 atgcgtgatc gtttctttcc tgagcaaaga tgttaaattg aacctgacct ttatgtttat
     4141 ccgcagtaag gtgctgtttg gcgacttcgt ccggctgtca cttcccgctc ttggaaatga
     4201 cgtttcctgg agtgttgctt tctccatgta ctctgtgatc ctgggacatc tcggaacaga
     4261 tgccgttgca gccaactctc tggttacggt tgtccgcaat atcggttctg tgttctgctt
     4321 tgcaattgcc agtgcgggaa cgattcttct tggaaatgta atgggaaaag gggatctgga
     4381 gaaatcgaag gtgtatgctt ccagaatgct gaagatgacc attatagccg gtgccattgg
     4441 cggtgtgatc gtatttgcca tcacgcctct ggtcctgaga tttgcatcct taagtgacgg
     4501 ggcaatgcat tatttgaagt acatgctgct tatcaatacc tattatatta tgggttctgc
     4561 ggtaaacaca gccctgatcg ccggggtatt ccgcgcaggc ggtgatacga agttcggact
     4621 gatctgcgat accattgata tgtgggtata tgcggtacct ctgggatttt ttgcggcctt
     4681 tgtcctgaag cttccggtat tgtgggtcta cttcctgctc tgtacagatg agtttgtgaa
     4741 atggccatgg gtattccatc attaccgcca ggggaaatgg gcacagaata ttacaaggga
     4801 ggatctgttt gagcagaaag cttcctgaga tatcatccat atccgccgca gtgtggttct
     4861 ataataaata agcaaaacag caggtctgtt cattctatga acaatcctgc tgtttttatg
     4921 tctgcagatt ttctttccgg atccctgcag acatccattt tcggtttata aaaaatgctt
     4981 acagattata atgtattcag gtcgattctg taatcgtcag agccctgtcc gtctactgtg
     5041 tagtaagcgg ctttctgctc aacatttaca taaacgctga tttcttttcc ttcgatgcct
     5101 ttgtctttga tgtctttttt gattgcttcc tcgatggagc tcattgtaac tgcaaaacca
     5161 ggtaattcga tagttgtttc tgcgaatttt ttgatgtcga tatttttagc cacttctttt
     5221 actgctttct ttacagtttc ttttgcttct tctacaaccg gagccttcgc aatatcagct
     5281 gcagcgtctt ttgcttcttc aattacttct gaagccttta cagttgtttt ctcaactgtc
     5341 tctttgactg cttctgtagc ctttgttgtt gcttctttaa tagtttcctt cgctcttgaa
     5401 gttgttcttt ttctcataat aatctcctat tccaactgat tggtctagag cgtgatccat
     5461 ccggaaatac tggacagcat catctcccga aacagaactt tcatgattac tgtttccagt
     5521 ggcagactca aaagcagaca gaacaccacc accaaagacg tggacataat atatagcttg
     5581 ctgatctcgc catttgtata gcccaggatt tttaccattg aaatagactg ggcatttttt
     5641 tcgataatga tcttggaaag aagatagatc agtaccatat agatcataat ggcaaatccg
     5701 tttaccatac ccatcatact tcccatggat acatccagct gtctggagat ctttgtcagt
     5761 gcatcaaggt caactacaga tcctatactg gctcttgata tctgtaagct ctgtatctga
     5821 gaaataccca ctgtaataat cctctcccaa atcaaaaata tcattcaatt cactgcgggg
     5881 cataaacaca caaggcagcc gtataatcat aagctcctgc tattttaaac gaatatttct
     5941 ctttttcgta tttttctttc agagtgatgg tatcccccac atgaagcagg aatttatccg
     6001 catatgcgct cgaaatataa actgctgcgc tttctttttc tgcatttgcc gtattcttgt
     6061 tatctgcttt ttctttattc cccgcttcat cttttttatc ttttgtatta ttaaaatcta
     6121 tcgttacata aaaagcttag atttttgtct tgacaactga accactatac tgtaccagtc
     6181 aatcacagct gttaaatata aaaatccatg tttaatggcg atatatgtga tatcgattga
     6241 ccatgcctga ttaggacggt cgataacggc gttacgcagc agatacgggc agactttagc
     6301 ctgttgcata cgtttagaaa ggttcatttt tggatagatt ggatcaatcc ccatttcatt
     6361 catataacgg cgcgttttcc ggcggccaac ctgatgccct cgtttcttca gttgagcaga
     6421 cagttgtcgt gctccccagg ccgggttatc cgtgtgtaat cgatctatga tcgatttgca
     6481 atctaactcc tcctgagata tgggtgtgcc cttgtaataa acactggtac gattgatatc
     6541 aagaagcgca gctcctgttt taactggaag ttctttagtc ttcaaaaagt tttggactaa
     6601 atttactctc gtagtcaggt ccaagtgttt cttcagattt tttttcaacc aatccacctg
     6661 catggtgagc tggccaactt ttttcgcata ttcagctttt tccttgcgct ctaaagcaag
     6721 tttttctttc agattatcct ctcgtgtgtc atcaaaaacc acggatgctt tatcgagaaa
     6781 ttctttcttc cagttgcgga gaagatttgg ctgaatattg ttttcgcttg caattgtatt
     6841 taagtctttt tctcctttga gcagttcaat cactaattct gatttgaatt tggcggagaa
     6901 atttcttctt gttcgagaca taataatgat ccttctttct gtagtgttta cagtatatca
     6961 gattcattaa gaaatgtctc ttgaagtgtc ttaaattatg ataccattat actccggctg
     7021 aaaacatcag cctgccaaaa gacaccataa ccctgatgtg ttttggcaga ctgttttctg
     7081 tctgcatttc tctttatttc tttaaccgga taatcatatc tgcccagaat tctgtgtatg
     7141 cctgccgcat taactccaga agccgggctt cggtaattcc tttaattacg ttttcttctt
     7201 tcttttccgg ttttggttcc tgttaaagtt cattctgcat tcttttatct cctcgttgat
     7261 tacaggctct attataatta caaatccttt ccctggtaat ggactatgga ggcaagattt
     7321 cccagtttca ttaccatttc tttccttttt tggttttaga gatttattat atctgaacga
     7381 gttgaaaacg atttttgcac catttacgaa aaagcactgc attatctctt caattaggca
     7441 taaaaaagga gagaacgtca catatcgact cctctccaat agcttctatt catctaagat
     7501 atttgccaat acataggctt acttgttttt tctttccagg aacctccgta tctcttccac
     7561 actatataat atgggaatgg acggggcaga cgggctgcat acaggatctt gactggacat
     7621 ttccagtgca ttaataaatg cttctgcctt ttttgggtct tcaatcacaa gctctgtaag
     7681 gatacttgat gtagccatat agaaagcacc tcttttctct catatcttaa aaaattcttt
     7741 cgtaagaaga tcctgcagta ttttctatac gccaagacct gtactctcca tttttattta
     7801 tgtaataaag tttgatccag catgttttta atttcatctg gaagaccgtc taccgttgca
     7861 ttttcatcta aaaacagtaa atttgtatat tttttcgcat cattcggcgc tgaaaaaata
     7921 tgagttactg tatatgctgt tctactttta gaaaagcaat cttcatctcg tagcgattct
     7981 actacaaagc aatcgccctt ttgctgcccc ttatcatcat actctttatt taagcataga
     8041 gtaaaattaa gatctgttgt gccaaactta taagttctcg tgtctgtgac aatctcttcc
     8101 agcataaatc cttctgagcc agccagcatt gcaatctgtc cgatatgctt aatcttacgc
     8161 ttacacaatg aaaaagggtg ctgcggtgta aaaaatatct gcgaagcctg aagcatcttt
     8221 tttgctgcat aactataaaa cttttttgct gaaaggttcg tggccacacc tgtcaagtgc
     8281 ctaaaattgg cagctttata aagcacctca atatatctgc cttcaaatac atatagaaat
     8341 cttttaccta ctaaatgctt cctatacaga tcagcagcca ctttaatttc ctgtacaatt
     8401 ttctctctat cctgttgttt tcccatctat cttttcccaa tcatcaccat agtataaaaa
     8461 aacagcactg gacaactttt ttgttatcca gcgcccataa tcttaaaaag cggttttatg
     8521 ctggctgtca gccgcgacat ccttccgaat gtctaaaatg tcgccggtat cattgagtcc
     8581 ccggcgcgga ctcaccgtat ctccctggtg tgggcgtaat acccttccga gtatcaaata
     8641 gtcccagtaa ttaccctgcc cgggcacagt acagctttta cgtgccgcta cacgaaacct
     8701 tttggcttaa ctatattata tgcgataccc taagaaatat caatagtttc cccaaatttg
     8761 tatcctgttt tatcacgtta attactgttt taataaactc cttctataat ctgtatccaa
     8821 tactatttta tggaaatccc gcattgcacg ctcttgcatc agtttctcac caagttttac
     8881 aagaggattg gtttcccatt cagaatcaat tcctgtttga tgatagtatc ttgcataagc
     8941 aaatccctca gctaccgcat ctgaattttc aaatactccc actattgcat ctgtaaactg
     9001 tacaatgatt gagttcccaa aaataccctg caattcttcc gcattcgcat catcatattt
     9061 ctctacatca aaagataaag agaaatcata cgtattctct tttccgtctt ctgtttcata
     9121 agaaactgtt ccaaaaatat ctcctttgcc agacggaagt tcgattgact ctgaaagctc
     9181 taattcatat tcaatgttat tgaacactgt cgttgcttca aacatttgtg atatacaggt
     9241 accttctttt tcataaatat ctttctgtaa aaaggaaata ggattatact ccatattttc
     9301 ccatatctgt tttccctcca ctgtccgttt acacaaggaa tctaaaagca acatcattgt
     9361 ttcctgatct atttcttcat atacgttcat agtcagcctc ctttttcttt ggatagtcca
     9421 caaaagctct gtaagagttt atcttaattt ctagttacaa cgtgatattt agtcaaatga
     9481 cgtatgtacg cgctttctta tagttgccaa tattatatgg cgtatctccc aaaaattcaa
     9541 tcagaatata aaaactttta ctcacactat cctgccttta catctttttt agtctatacc
     9601 ctacattgat caatgtttct ataatatcat gccccatctt ttttcgtatc ttccatacta
     9661 cgtgttccac tgttttgtac ggaatctgat catcataata attactctcc cagaccgaac
     9721 aatagatatt cttctttgga ataacccaat ttggtctttg ggctaaaaga tacagaactt
     9781 caaattccct gggagctaag ctgatttctt ttccttcata aataacagta tatgacatgg
     9841 gatcaagttg aaatttacca tttcctaata caatttcaga tttatattct ggaaaaacgg
     9901 tttgcattca ttttcacctc catgattttc tatcccagca atcgtttcaa aactctacac
     9961 acaataaaaa tgcggaaata atagacccct atcattcccg ctaatttttc tctttttcaa
    10021 ctttatactt tatgataccg atacattgtg atataaaaac ggtcaacgct gtcaatgcaa
    10081 tcaaagatat atactttttc atacctaaag ctgtacaaca gcccgtagca attaaaatag
    10141 ctcccagtat tttacctgtt acttttcggc aatgctcctt ttcttctctt tccaactcat
    10201 ggttaatgtt ttctacagga gaaagtttcc atatacaaat ggaacttacc aaaataatcc
    10261 cccaagccac aaatagctct aatggatatt tgttattaat ttgtaaaatc atgacttgaa
    10321 cagcaacaga gcatgtaaaa caagccttaa agctattcag atgtacacca ccggcatagg
    10381 ttcttaaaaa cataaaaaca ccggtagaca caaggaattc tgggattgta tgcaagtata
    10441 tcgctatact catacagacg aataggcaaa ttaacatctc taatccaatc tgaaatccat
    10501 attgatatac tgcatacaac tcctctgaaa ctgcaccggc atcaataacg tatcttgtta
    10561 ttttttccga taattttccc ataaaattaa agtttcttca tttttttcaa tgcttctggc
    10621 atctttggct gatgataaat ataacagcaa gcactgtccg ctgacatttt accaagtttc
    10681 agagataaat ttgctaatac ttttgctggc tgatttttta aatttttaga tttcataatt
    10741 aaaatctcct ttcatttgtt taccaataca ttactacaaa aaatctccca ttcggttctc
    10801 ttgtaaaaaa accgagtatt gatgtaattt ttcccaaaaa ggcagaaaaa aagaagcaat
    10861 gtttctccgg ttctttctca acattgcctc ttttttgctg atgtatgttt ttttatatac
    10921 caattccata aaatcaggtt ctctatcttt ttcttatatt ttcgtgtgtt atctattgtt
    10981 tctatataat cgtaagctcc tgctttcagt atagaaaaaa tatcctgtat tgatccccct
    11041 tcgctaatag caagaatagg cgttaaatgc cccaaactcc cttttatttt tataatagcc
    11101 gcaaatgccc tttccctctc tattatctct ttagtaaaat ggaaaatcac aacatctgcc
    11161 gttggatatc tattgttttc caactgttga taagtacacc attttaattg gtgttttttc
    11221 ccaataatcc tttcagtact gttatacagt ttctcatcat cactaaacag caatattttc
    11281 acgctatcca tatatcagtc cccataccgc ataccaaatt tatctttcca ttttaccatt
    11341 gtttcctttc tcattatttt ttatgtaatt atttcgagtg ttcatgtaat tattcctgca
    11401 cattactata taagactatc cgaattttaa attttcctgg ttctgaatcc tctattacca
    11461 ctgatccatg atattttgct actgcccgat acacagaggc taaacctact ccatgatttt
    11521 ctgcatctga ctttgtagat ttcaagcggt tatctcttgt ttttaacagc ttccctttat
    11581 aactattgtc tacgaacaat aatagattat ttttatcaaa tttcattttg acatttatat
    11641 atctattttc ttcaaccttc tctgctgctt ccactgcatt ttccagtaaa tttcccaata
    11701 tcagactcag atcagctcct ttaaaaggca ttatcatcgg aatacaaata tccgttttaa
    11761 aaattattct tttgttttgg gcagttacat accaatatcc aataagtgaa tcaatcacaa
    11821 tattcccact attcgatatt gaggcaatca ccataccgcc ctctcccata atttcttcaa
    11881 taaaacctgt cattttttca tattctttat tttctgcata agcaagaatg gaaataagat
    11941 tattcttcat attgtgtttt atatcccgca actgcaacat tgaaagttct ctttcttgct
    12001 gatgacgttc gcataattcc agttgctgtt catatactgc tgccattctc cttaaccgca
    12061 aatcatcagc caacttcata tagacataaa atatcaatat gttcatacca agtaaaataa
    12121 gtacagtaaa tgtagagttt atacgagtac gtccattatt atttgcaaat ccaagcataa
    12181 atatattgtt catgatataa atgcttcctg ttgggatcaa cacaagtaaa atactgtatc
    12241 tgaccggcaa ttccttaata tcatcatctg tgaacacttt ctttaatgca agaattactg
    12301 cattaaaaaa tatttttgaa acgaaagagc ctacttggcg aactgcagca tattgagggc
    12361 agtatgttat caaaatatag ttgcacaggg tttccatcaa catccaaatc gcattaaagg
    12421 taattacaaa tacacctttg ttccaccatc taccttcata agtcatcata actgccaaaa
    12481 acgtaaacat aatcgtcaca gcaatattga tgtaggcagg aaaactaata atcgttgtta
    12541 ttccaaattg ccaaatcacg aacagcgtta taccgatcac cgacaaatac ctttttctct
    12601 tacgagcaaa aaatatatcg aaataaaaaa agaataaata tactgcccaa aggcaaagca
    12661 atatatctat cccacacatt aatacactat tcgtccacat aaaacgtatc ctccatagaa
    12721 caatattgtt cactaattat ctttctccgg tcttcactga ttgaaatttt ttgtccatta
    12781 tccattacta cagaatcata agattgtccg gatatatgtt tataattcac cagaaaagac
    12841 tgatgaactc gcaaaaaaga aattttacat gttttaaggg tttcttcaat ctcattaagt
    12901 tttccgtaca gttcaaggat ttcttgttcc gttacaataa atatttttcg tttgttgctt
    12961 tcaaaatata aaatatcctt gattggtact ttatgattca tacgttgata actatagcga
    13021 aaataaaaat cttcactatt aatgtcttca tataccgact taaagcactt ttccattatt
    13081 ttatctgtta caggttttac aagaaactga aacggtctta cctcaaagga ttccctcata
    13141 taactttcat ggctcgtaac ataaataatt cgcacatttt tatcgtatgt tctaattctt
    13201 ctagctgccg aaataccatc ttctttatcc atttctatat ccagataaat aacatcatac
    13261 ctctcacctg ctgcgatagc atctgctaaa ctctttccat tccagaatac ttctatttca
    13321 gtatcaacaa aatttctttt agctatatcc tggagaagtc tttcgatttt tccagttatt
    13381 tgaatatcat catcacaaat tgctatattt aacattcact ccactctctt ctgcatgttt
    13441 gctgattttt tcttctcact cgttttttta ctatttgtat acgtgaactt cctgaaaaag
    13501 taacactcaa attgcccttt tctcatcaaa acagtccaaa atctaattta ttccgccatc
    13561 agaacagata aatgccatga tctcttcata tgtttttgta ctgttttcaa cagctttgag
    13621 cagttctttt ttcttctctt cgttcctttt tgcatgaaga tctttcagtt tcatcatttc
    13681 ggaatcatac ttttctttta cttttaatac cgtctcttcc tgcttcttta tctgctcttc
    13741 caaagatatc atttttctcg gtcttgccat atattatttc ccctcttctg catatttttc
    13801 aagcagtctg ctcaatccta cagctttgtc ctgtatctgg tctgcatcca tatcaaatgc
    13861 ttttaagatt attttctggg ttgctgttac tgcatgatcc atacaatatt ttccatctgt
    13921 ctgacggacc agctctatct tttccagttc acggatcgct gccggaacag tcatataatt
    13981 cggcttttta tcaagttttt ccatttcatc tttcagcagg acatacatcc tgctccttac
    14041 tatcagcgct acaaattcca cgaagatctt cgcatttgca gcctcatctg actgtacccg
    14101 caggctcctg ttcccaagat aactcttatc tcccctgaac agtttttctg atacatccct
    14161 gctcttatat agttccaaag cttcttccgc tgtcatctgt tttgacgtta ctatcacaaa
    14221 atatccgcac agatcgatct cttcctggat cacttctgtc ctctcccttg cgcatatgat
    14281 cgtcccatca tccttatata tttcaagttt aaaatacttc ttatatccat cccctacggt
    14341 cgctttttct ccctttaaac ccttaagata tttcgtcatc cggtctattt ttgcctctat
    14401 ctgttcatgt tccacacacg ctttctggtc tgaataataa atatgaaaat atctttcttt
    14461 ttcatctgat atatagagtt ttttccttat tgtctttcca aatgtcttgt acttccgtat
    14521 attgtattta cgaatattct cgaattctcc tttgttttcc aggatcatcc gcctgacaga
    14581 ttcactcata ccctttacca tgatcacaaa atcatatccg cattcatcca tataccggat
    14641 gttttccctg ccaaaatatc ccctgtccag gataaatccg accttcttat atccgtatcc
    14701 ttctgctttt tttaacatat actggagctg ggaaatatct acgatacttc caggatactg
    14761 ctcataaaac aacggtaagt aagtaatcat ccgtatctgt tttttcattt tttattctgc
    14821 tacaatctcc ttaaaactca ggaggtattc tatacactat gaacaaagaa gaaaaagcaa
    14881 aactctgggc tgaccgtatc cagcaataca aaaccagtgg acaaacgtgt aaacaatggt
    14941 gtgcagaaaa cgatatccct ttatctacga tgggatactg gacccgcaga cttgctaaag
    15001 aagatccggc atctgaacct gaacaggatc tggtctttgc cagactgcca tctgaacggg
    15061 aagctgccag aaagcttctc tctgaagaaa ctgcaccggt gcgtattttt gtctcagaca
    15121 gtatccgtat tgaaatatct gattcctgca gaccggaact gatggaatcc atactgggat
    15181 tcctgcagtg ccatgcttga cctggcagga ggaacaacgg tatatcttgc ctgcggagtc
    15241 actgatctga gaaaaagtta caatggtctg gctgccatca tcaaattaaa atttcacctc
    15301 gacccatact cacgctgcat gtttgcgttc tgcaaccgtc ggcgtacttc tataaagatc
    15361 ctccaatggg acggatccgg attctggatc ctgatgaaac ggctcgaccg taatgccttc
    15421 cactggccgg atactccgga cgaactccgc caggtgactc tgaaagagat ccactggctg
    15481 tgtgacggac tatccttaaa tcccagaggt gcatttgagg aacaccatcc aaagatcatt
    15541 ctgtaagcat acgacagcgg agctgtcaat cccgtaaaaa tcatgaaaaa tacgacatct
    15601 tcctgcatat ttcctatatc cggaaacgca gttttccata ggaaaacagc tgtgatcatg
    15661 gtatactttt gataatgata aaagccggga ggacaggaca tggaaccgat ctttacagat
    15721 aaacagctga ataacatgag ccgtgaagat ctgatctcat tgatgaagat cgtacaggaa
    15781 cagacaaaga agaaggatac ggagatccag ctgctgaagg ataaacagaa ggaactcgaa
    15841 ttcttaaatg ccatgctctc tgaccgtctt accccaatgt ggtcaactta agcccagaat
    15901 gctgaaaatt caaccattct gggcttatat tctggatttt ttatataaat atcttgacat
    15961 atcctcctaa atatgtggtt tatagattaa gcaatattac gttaccagcg aaatatttat
    16021 ctattccaat acgtaggagg tatgccatat gaatcgaact aatatttgta aaaatatcgt
    16081 ccaatccatt aaagattata tcacagatca agttaaactg gaaccccatc gggtggaaaa
    16141 acattttgta cggcgaagaa aactttccct tttgcaagtt attatttatc tgttcttctc
    16201 ttcaaaagct tcc
//
