LOCUS       c00041_gnlPro..        13673 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NEOAMHOM_52.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 17:08:24
            Original ID  :: gnl|Prokka|NEOAMHOM_52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13673
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..117
                     /locus_tag="ctg41_1"
                     /transl_table=11
                     /translation="NVVCLLENVPDRWPLFLATVKFPGRGYLVFYSWLKETR"
     protocluster    1..13673
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[183:3673]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      184..3673
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13673
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13673
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(90..209)
                     /locus_tag="ctg41_2"
                     /transl_table=11
                     /translation="MPRKASASKEDSFLRRSTKTPGGLGCREFFYYRVSLSQE"
     CDS             complement(184..951)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_3"
                     /sec_met_domain="Fer2_3 (E-value: 1.8e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.7e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENRDAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(992..2950)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.1e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.2e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.1e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAITGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTASPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(2972..3673)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_5"
                     /sec_met_domain="SucD_FumR (E-value: 4.3e-13, bitscore:
                     40.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLGVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLVYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3838..4146
                     /locus_tag="ctg41_6"
                     /transl_table=11
                     /translation="LTRLSAQAYRLCVKRSKKEVLDADFAAARAGVLDVAAFLDRVDRG
                     EGEADFRYRALMEVLPLLSASGPGRVRAILEALSYRDDAVPETAAAKAACGAPNLSK"
     CDS             4119..4964
                     /locus_tag="ctg41_7"
                     /transl_table=11
                     /translation="MRSSEPQQIRMMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAF
                     WAGYDRSSVDGFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFAREVMKLIP
                     EFIDRPNVLGIGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMIL
                     SALKNRPDLDPCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMD
                     RVWANSAADWGDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR
                     "
     CDS             complement(4961..5224)
                     /locus_tag="ctg41_8"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLCRYFKSRKGEPRFFNKRNICLLAAASAYILTPD
                     EFLFDGIGKLGLLDDAAVILGAVLTVLFSGWRLTARTHRRRN"
     CDS             complement(5649..6356)
                     /locus_tag="ctg41_9"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQDQIGQLMSEIASVPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             6394..6561
                     /locus_tag="ctg41_10"
                     /transl_table=11
                     /translation="MYLCLNNEFGIRYXXXXFGIRYKLPSKRNNKYEENTDTFNRDGKL
                     CCFLGGSDRF"
     CDS             6518..7228
                     /locus_tag="ctg41_11"
                     /transl_table=11
                     /translation="MGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLSLGSSSLAPSDS
                     SSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNTGTTAAGINLT
                     FSFSSLDGSPLLLDAALTYRFLAVSQSVMGLMQDTSKTYLYAAGGTAAPTANTEGDTVT
                     ISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEMVPEPATVSLG
                     LLGLAALMMRRRRA"
     CDS             complement(7330..7767)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_12"
                     /sec_met_domain="Acetyltransf_1 (E-value: 2.1e-08,
                     bitscore: 26.1, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPIAVLPEYQRRGIGRRMIGYTRNRAREMGFRAIFLYGDPDYSS
                     HCGFVPAETLGIRTADNRYAAALQVCALQRGSLSGLKGRYVEAAVYHMDEKRAAEFDRH
                     FPVKKKLSGIASQKRFQQIAAMRRKPDTAPCPRKSRTFRRA"
     CDS             7805..7990
                     /locus_tag="ctg41_13"
                     /transl_table=11
                     /translation="MTDVASTMFPDDAAAVDGDCILLRDEGRTDAHDMEQVMFIAAGDE
                     IVSERFSRDMFRFGMV"
     CDS             complement(8034..9239)
                     /locus_tag="ctg41_14"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSAGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPTKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9263..10009)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_15"
                     /sec_met_domain="adh_short_C2 (E-value: 5.4e-75, bitscore:
                     243.5, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFLQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLALEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10138..10476)
                     /locus_tag="ctg41_16"
                     /transl_table=11
                     /translation="LAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDAL
                     IEKMKKRMEMLDNRCRQEGKRPFEARYYGSAALKDILENSDEFSGLVEPDEDGAPPNAI
                     RENEEAGQ"
     CDS             complement(10719..12266)
                     /locus_tag="ctg41_17"
                     /transl_table=11
                     /translation="MTINWGERVALVGPNGAGKSTLFRMILGEDTPDEGSISMDEYAIV
                     GYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANG
                     YQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLD
                     LLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDV
                     RFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVF
                     KFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKI
                     LAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEARSILGS
                     FLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKH
                     YEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGGITAE"
     CDS             12569..13159
                     /locus_tag="ctg41_18"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
ORIGIN
        1 aatgttgtct gtttgttaga aaatgtccct gatagatggc ctctcttcct ggccactgtc
       61 aaatttcccg gaagaggcta tctggtattt tattcctggc tcaaggaaac ccggtaataa
      121 aaaaactccc gacagccgag gccgccggga gtttttgtag agcgtcttaa gaaggagtcc
      181 tctttagaag cagaggcctt ccttggcatt ggcccgcatg aagtcgcggt tgaggcgggc
      241 gatgttgtcc acgctgatgc ctttcgggca ggcggcttcg cattcgtatt ggttcgtgca
      301 gttgccgaag ccttccgctt ccatctgctt catcatggcc aggacgcgct tggagcgttc
      361 cggctggccc tgcggcagca gattgagatg ggcgattttg gcggacgtga acagcatggc
      421 ggaggcgttt ttgcaggagg ccacgcaggc gccgcagccg atgcaggcgg cggcgtcaaa
      481 ggcggcgtcc gccttcactt tttccacggc gatgttgttg gcgttcggcg cggagccggt
      541 gcgcacgtca atgtagccgc cggcggcgat gatgcggtcc agggcggaac ggtccaccat
      601 caggtcccgc aggatcggga aagccttcgc gcggaagggt tcgatccaga cggtgtcgcc
      661 gtccttgaac ttgcgcatgt gaagctggca ggtggttacc tggcgttccg gcccgtgggg
      721 aatgccgttg atggtcaggg agcacatgcc gcagatgcct tcccggcagt cgtggtcaaa
      781 atggatgggt tccttgcctt ccttgaccag accttcattg acgatgtcca gcatttccag
      841 gaaggaggca tccaccggaa tgtccttggc ggcataggtc tcaatgcggc ccttggcgtc
      901 acggttttcc tggcgccaga ccttgagagt gagattgagt gttttagcca tgttataatc
      961 tttcttttaa gtgttaatgt attggctatc tttacttgta gctgcggatg gcaaggtgca
     1021 cgttctcgaa ggtcagcggt tccttgtgga gaacaggcag gctgtccacg ccggtgtatt
     1081 cccaggcggc tacgtaggcg tattcatcgt cgttgcgctt ggcttcgccg tccggcagct
     1141 ggtattccac gcggaagtgc gcgccgcagg attcctgacg gttcagggcg tcatagcaga
     1201 gcagctgggc gaattctagg aagtcagcca cgcggcaggc tttttccagt tccgcgttga
     1261 tgccgtccgc cgtgccggtt acgcgcacgt tttcccagaa ttccttgcgg agctggggaa
     1321 tgcgttcaat ggcgtgggtc aggctttctt ccgtgcgggc catgccgcag tcttcccaca
     1381 tgatgaggcc cagttcccgg tggaaggagt ccaccgtctt ggtgcctttc acgttcagga
     1441 gtttgttgat gcgttccttc acctcgtctt ccgcggcctt gaattccggg gaggcggtgg
     1501 tgacggcgcc cggcttggtg gtcgtcaggt aggcgggaag cgtggctggg atgacgaagt
     1561 acccgtcaga caggccctgc atcagggcgg aggctcccag gcggttggcg ccgtggtcgg
     1621 agaaattggc ttcaccgagg acgtgcagcc ccttcacgtt ggacatgagg ttgtaatcca
     1681 cccacaggcc gcccatggtg tagtgggagg cggggtagat catcatgggc gtttcatggg
     1741 ggtcgtcgtc cgtgatttct tcgtacatgt caaacaggtt gccgtactgg ccgtcaatcc
     1801 attcgcggcc catgcgcttg atttcatccg caaagtccag gaagactccc ttgccggtga
     1861 tggccacgcc gcggccgtcg tcgcaggctt ccttggcggc gcgggaggaa atgtcgcgcg
     1921 gagccaggtt gccgaaggag ggatatttgc gttccaggta gtagtcccgt tcttcttcgg
     1981 gaacatcgga aggcttgatt tcctttttgc ggattttttc cgcggtttca cgggacttgg
     2041 gcacccagat gcggccgctg ttgcggaggg attccgacat cagcgtcagc ttggactggt
     2101 agtcgccctt gaccggaatg caggtggggt gaatttgcgt gaagcagggg ttggcgaaga
     2161 aagcgccgcg cttgtaggcc ttgtaggcgg cggtgacgtt gcagcccatc gcgttggtgg
     2221 acaggaagaa cacgttgccg tagccgcccg tgcagagcag gacggtatcc cctgcgtagg
     2281 acttgatttc accggtgacc agattgcggg tgacgatgcc cttggcttct ccgtccacca
     2341 gcaccaggtc catcatttca tggcgggaga acatttcaat gtgtcccttg gccacttcct
     2401 tttccaaagc ctggtaggca cccagcagga gctgctggcc cgtctgtccg cgtgcgtaga
     2461 aggtacgctt aagctgggcg ccgccgaagg agcggttatc caggaggccg ccgtattcac
     2521 ggccgaaggg aacgccctgg gccacgcact ggtcaatgat gttggaggag acttccgcca
     2581 ggcggtaaac gttggcttca cgggcgcgga agtcgccgcc cttgacggtg tcgtaaaaca
     2641 ggcggtaaac ggagtcaccg tcgttctggt agttcttggc cgcgttgatg ccgccctggg
     2701 ccgcaatgga gtgggcgcgg cgggggctgt cctgatagca gaagcatttg acgttgtagc
     2761 caagttcggc aagcgtggcg gcagcggagg cgccagccag gccggaacct accacaagca
     2821 ccgtgtactt gcgcttgttg ttcggattga tcagtttgga ttcaagcttg tacttggacc
     2881 atttgtcctg aatagggccg gagggaattt tggcatccgg catccagtcg cttacgggaa
     2941 aattaatcat ggctttgaga ggagttgatg gttatttgat gatgcccaga agaaccgaga
     3001 ccggcacgga gatgaagccc aggcagataa tcgcgccgta ggcgatggcg ataaaattgt
     3061 agaagggccg gattttgcgg gaatcaacgc ccacagtctg gaagatggac tgtaccccgt
     3121 ggcgcagatg gctgaacagc atcagaacgg ccaggatgta gaaggcggag caccatacgt
     3181 tggagaatcc ggtcacgatc attttgtaca cgtcaaaggt ctccaccgta ccgtcggaaa
     3241 tgaaggtggt gaactgggcg gggtcgtatc ccacgcgcag ggtgtattgg tacaggtggt
     3301 agaccaggaa caccaggacg gtcaggccgg tgtaaatcat gtagcgggag gagagcgtcg
     3361 ccttgatggt gttcttgaac acatagggtt cgcgggccgc atggttttcc agcttcagct
     3421 ggatggtcag ccagacatgg atgatgaaga tcaccccaag ccccgcgcga atgccccaga
     3481 gggctgcttc cggcatggag tgcaggccgt gggcgtaggt gttgatccat tcagggcctc
     3541 cgaagatgag aaggttgcct gccaggtgtc ccgcaaggaa caagaccaaa cataaccccg
     3601 tcagagccac aatgattttg cggccgatgg aggatgtcac gaatgtacat atggttttta
     3661 ctagtgcatt cataggcgct ctaatgaaat aaatgcgtcc tcacaggatg cccggttcaa
     3721 gcccggatgg caagcctctt cttgaatttc cggcgctttt cggatttttg aaaagccggg
     3781 gaaaggcgtt gctgtttatc agtttggaat agttattatt ttgttacctg ttccggcttg
     3841 acgaggcttt ccgcacaggc gtatcgtctg tgcgtgaaaa ggagtaaaaa agaggtgctg
     3901 gacgcggatt tcgcagcggc gcgcgccggc gttctggatg tggccgcatt tctggaccgg
     3961 gtggaccgcg gggaaggaga ggcggatttc cgctaccgtg ccctgatgga ggttcttccc
     4021 cttttgtccg catccggccc cggacgcgtc cgggccattc tggaagccct ttcctacagg
     4081 gatgacgccg tgccggaaac cgccgcggcc aaagcggcat gcggagctcc gaacctcagc
     4141 aaataagaat gatggctttc atagaacctc atatacatat ggtgtgccgc accacggacg
     4201 aataccgggc catggcgcag gcaggctgcc tggcggtagg ggagccggcg ttctgggccg
     4261 gttatgaccg ttcgtccgtg gacggtttcc gggattattt cgtacagctt acggaatgcg
     4321 aacccgccag ggcggccaag ttcggcatgg accattacac atggttgtgc atcaatccca
     4381 aagaggcgca agacgtggcc tttgcacggg aggtgatgaa actcattccg gagtttattg
     4441 accggcccaa tgtccttggc atcggggaaa tagggctgaa ccggaatact tcccatgaaa
     4501 tgaccatttt tgaagagcat ctggatctgg cggtgcgcct caaccagctt gtgctgattc
     4561 acactcccca tttggaagac aagctgaagg ggaccgtaat gattctttcc gccctgaaaa
     4621 accgtccgga tctggatcct tgccgcgtgt tggtggatca ctgtgaggaa cataccttcc
     4681 cgctggtgaa ggaggccggc tactgggccg gactgaccct ttatcccacc agcaagctga
     4741 atcccaagcg ggcggcggat attctggaat tgtacggaat ggaccgtgtc tgggccaatt
     4801 ccgcggcaga ctggggggat tccgatcccc tggcgctgac ggctctggcc tgcgagctac
     4861 gcaggcgcgg tttttcccgg caggaaacgg aacgtcttct cttggaaaat ccggagacat
     4921 tcatgggaca gtctccgaag ttccggaaag tgtcgtcccg ctaattccgc ctgcggtggg
     4981 tgcgggccgt tagtctccat ccggaaaaaa gaacggtgag aacggctccc aggatgaccg
     5041 ccgcgtcatc tagaaggccc agcttgccga ttccgtcaaa caggaattcg tcgggagtca
     5101 ggatgtaggc gctggcggcg gccagaaggc atatattccg tttgttgaaa aaacgcggtt
     5161 ctccttttct gcttttgaaa taccggcaca gacgcagcaa cagctgctgt ttttgaaggt
     5221 tcatgaggaa cggggaatga aggttaaagc tcagtcattt cccctctttc cccctgtttc
     5281 agggcgagag gtcgcttcca gcggacggaa gcgcggtgac tcggatcatg cggggaaatg
     5341 aattgctgag aggatggcct gttccggatg cagagggaat ccggactttg cagggcccgg
     5401 ctccggctgt tccggcatgg gaaaaaaggg cgtgtacgga agtggggcgg ggccggaagc
     5461 tcttgaaatg accctcccgg gggagactga atgccatttc cccgtcaagt gctggccgtg
     5521 aggttgccgc agcaaatgga agcttcttcc ccctgttttt ttcggcagat gtttgagagg
     5581 ataaggaaaa ggccgactca cgattttgtg agccggcctt tgaatatagg gaggcggacg
     5641 gtacaggctt atgccctgcg gcggcgcatc atcagcgcgg ccagtcccag caggcccagg
     5701 gaggccgtgg cgggttccgg aacgctggcg atttcactca tcagctgacc gatctgatcc
     5761 tgggaaagaa gggagtcgtg gatgtagagc tgttcgatgg attcagccag tcctgcgtcc
     5821 atgagaatct gattaatttg ctggttgccg aatttcaggc cgctgttgga atagtacgta
     5881 gcgctgtcgc caaaatagat gcgggtgcca agatctccgg tgactacgga aatggtcagg
     5941 gaaccttccg tgcccagcgg ggtgtcaacg acgggcccgt tgtatgaggt gttgttccat
     6001 aatccctgga gtttccggtc cgtgttcagg cccacgcccc agcttacact gctgtttttg
     6061 gcgttaaaca gagcggtata ggcgtccgga gtgttgattt tggacaggtc aagaaccatc
     6121 gtcacagaca taacgtcgcg gttgttggca ccgtatccgt tgaaggttat cccggataac
     6181 gtcagattgc tgtcgtcaga cgtgatggaa acggaatctt tcagggtgcc gaaatccgcc
     6241 gtttgggagg caaagtccga atatcccacg atggagctat ccagcagaga ggtagccgcg
     6301 gtagcgctta ggctcatgcc ggccgaaaga atcagggtgg ataataattt attcatggtc
     6361 agtatcttaa taaaatgatg caagattcaa tgtatgtact tgtgcttgaa taacgaattt
     6421 ggaattcgct acaannnnnn nnnatttgga attcgctaca agttgccatc caaaaggaat
     6481 aataaatatg aagaaaacac tgacactttt aatcgcgatg ggaagctttg ctgtttcctc
     6541 ggaggcagcg accgttttta attattacac tcccggtacg gataattaca atagtaccat
     6601 ccatgggttt tatcttagcc tggggtcttc ttccctggct ccttccgatt cctcttctcc
     6661 ctcctccctg tccggagaga tcagactgga cagttttacg ctgcgcggag ccgccaacaa
     6721 tttgggcgct aatgtcactt acggcttcct ggtgctgaat ggctccgaca attcggtcat
     6781 cggctggagc accaatacgg gaactactgc agcagggatt aatctgacgt tcagtttttc
     6841 ttccctggat ggttctcccc tgcttcttga cgcggcattg acataccgct tcctggccgt
     6901 gagccagtcc gtgatgggct tgatgcagga tacgtctaaa acgtatttat atgctgcggg
     6961 ggggacagcc gcccctactg ctaacacgga aggagatacc gtaacgatca gcggcggatt
     7021 gactgctccc ggcatccgcg gccattatga cgccgaggga gcgcctggtg attctgttgt
     7081 tattacggga gccaacggaa ccaatacttt cagcttatta tctccgattt tcacggaaat
     7141 ccgaggggaa atggtgccgg aaccagccac ggtttccctg ggcctgctgg gactggccgc
     7201 gctgatgatg cgccgccgca gggcttgagc ttcctgatgg cgaaaaatcg gcggatgaga
     7261 gctgttcttg cggaacagct cttgtttttt atatccagag aggaagaatt actcatccgc
     7321 atgcgggatt catgccctcc ggaaggtacg ggatttccgg gggcaggggg ccgtatccgg
     7381 ttttctccgc atggcggcaa tttgctggaa acgtttttga gacgcaatac cggaaagctt
     7441 tttctttacc ggaaaatgcc ggtcaaattc ggcagcgcgc ttttcgtcca tatggtacac
     7501 ggcagcttcc acatagcggc ctttcaggcc ggatagggaa cccctttgca gcgcacagac
     7561 ctggagggcc gccgcatacc tattatccgc cgttctgatg cccagcgttt ccgcgggaac
     7621 gaatccacag tgtgaagagt agtccgggtc gccgtacagg aaaatggcac ggaagcccat
     7681 ttcacgcgcc cggttcctgg tgtagccgat catccgccgt cctattcccc ggcgctggta
     7741 ttccggaaga acggcaatgg gccccatgcc cagcacttca tattcttttc catcgtctgc
     7801 cctgatgacg gacgttgcat caacgatgtt tcccgacgat gcggctgccg tggatggcga
     7861 ctgcatcctg ctccgggatg aaggaaggac tgacgcgcat gatatggagc aggtaatgtt
     7921 cattgcagcc ggggacgaaa tagtttcaga acgcttctct cgtgacatgt tccgtttcgg
     7981 catggtctga ggattgttcc gttcttaatg caatggtcat gaaagattgt tctttacggc
     8041 tcccccttgg agaaattcca gaggcggtgc atcgtcataa tgtccggaat gttcatgggg
     8101 cgcaccacgc ggaacccgat catgcctccg tccgtcaggt accagatgct tttagggttt
     8161 tgaggatcct gacggttcca ggcgggggtg ctggcgcggc gcgcagcgct tctcaggctg
     8221 tccgggtcgt cttcccacga accgccgcga acgatgtgag gggcgccggg gatgatgacc
     8281 agggggtctt tcgtgggcaa gccgctccgt ttgccgtagg catccggaac gtaagagtcc
     8341 aaaacccatt ccgccacatt tccgtgcatg tcccggagtc cccacttatt tggtttttta
     8401 gagcctgttt tctggtagcg gtcattggaa ttgttccagt accaggcgta ctggtccaga
     8461 gaggcttccc cgtttccgta agaataggcg ccggcggaac cggcccggca ggcgtattcc
     8521 cattccgcct ccgtgggcag gcggtagtaa tgcccggtct gggcgctcag ccattcgcag
     8581 aatttgctgg cggcgtggtg ggacatggag atggcgggca ggccgtgttc atagccgtgg
     8641 cccatgccca ggttcatggc ggcgtagggg gcggtaggct gcgtgacgga gtcccacagt
     8701 tcgtcatccg gctgttcctc cagaagctgg ccgtccttgg cgcgcggacg cccgttttcc
     8761 atgaaggccg tataaagttc ccaggggatt tccgtttccg agatccagaa gggagagatg
     8821 ctcactttat gctgcggacc ttcgtccggt ttccggtgcg gctcttccgc gggactcccc
     8881 atgaggaacg ttcctcccgg tatggcgacc atgcgcaggg aagctcccgc cgcgggaacc
     8941 gtttccgtgt aggattcaaa acgtgccgga tttccggaag cttcaatgag ctgatggatt
     9001 tggcgcgtcg tgccgaccag ctcccgggac ggcaggtcat ccggaatggg aagggcagga
     9061 ccggcagcgc ggtccagttc ccgtttttgc agcgcggatc ggctttctcc ccactggcgt
     9121 gcgctggtaa tgcgcgcggc atcttccgtg gccgggcggg gggaattatt ttcttcccgg
     9181 cacccggcca gcagggcgct tcctcccaga aagcaggaaa caaggaaaat gccgcgcatg
     9241 gaatggtgaa aaccggaatg ccctacatcg tcatgcctcc gtcgcaggca atgacctgcc
     9301 cggtgatgta acgggcatcg tcagaggcaa ggaaggccgt cagggcggcg atatcttcca
     9361 cggaaccttg ttctttcaaa ggtattttct tgacgatttc ttccttgaga ttgtcgggaa
     9421 tggcattgga catttccgtg gagatgaagc cgggagcaat ggcgttgcac gtgactttgc
     9481 gcggagcgaa ttccagggcc agtgatttgg tgaagccgat gaggcccgcc ttggaagcgg
     9541 cgtaattggc ctggccgatg ttgccgacga gaccgatgac ggagctcatg ttgatgatgc
     9601 gcccggccgg ggatttcatg agaacacgct ggagggcctt gaccgtattg aacgcgcttt
     9661 tcaggttggt gtccagaacg gcatcccagt cttcctcctt catgcggagc atcagggagt
     9721 cccgcgtgat gccggcgttg ttcaccagga tgtcaatctg caggaagtct ttcaaaatgg
     9781 cggccatggt ttcctgaacg gccgcgtaat ccgctacgtc gcaggggtag gccttgcagg
     9841 aatccggaaa ttccttgttg atttcttctg cggctccccc gcagctggat ggactgcggc
     9901 tgatcaggat gaccctggct ccttccgaag cgaagcggcg cgcgacggca ttgccgattc
     9961 cgcgacccgc gccggtaacg atggctgttt tacctgctaa cttttgcatg ctgcccacag
    10021 taaacccgtt tttcacggtt ccggcaagct tgaaatggac ctggccgcgt aggaccccat
    10081 atggggaaag ggcgggccgg gaatgaaaaa agggggagaa acggggtgag ggggaggcta
    10141 ctgtccggcc tcttcatttt cccggattgc attggggggc gccccgtctt catccggttc
    10201 taccaggccg ctgaattcat ccgaattttc caaaatgtcc tttaaggcgg cggaaccgta
    10261 ataacgggcc tcaaacgggc gtttgccttc ctgcctgcag cggttgtcca gcatttccat
    10321 tcgttttttc attttttcta tcaaggcgtc ttctttctcc ttttccgcat cgttcaattt
    10381 atcctgaagc tggaggaaat gccggatgtc cttctgaatg tcctgcagcg ttttgacggc
    10441 gttgtccgcg ctttccttgt cctgaacgcc tgccaacgtc tgctggatat tgatggcaaa
    10501 ggaaaaggcc tggttgatca gggattccgc ggaaggaatt ttttccgccg gagccgctgc
    10561 tgtggggaag ccgttccggc ggccgtttca ccaaatgcaa gagaggctcc ggacagaagc
    10621 gcagaatata agagaggaac aagaaaagcc ttcatcctgt tcttttgagg caggatgaaa
    10681 tccacggcaa ggaaaaaggg gaaactgaaa aaagagcctt attccgccgt gatgccgcct
    10741 ttttcatcgt ccagaatgcc tgacttttcc agatagtagt catatccgcc tgcgtaggcg
    10801 gtgatggtcc cccggttcac atgcagggtt ttttgtgcca gggaacggat gaagtgcaca
    10861 tcgtgggaga tgaagaccag tgttccttca taatgcttca gagcctgcac cagggcttct
    10921 acggacaaaa ggtccaggtg ggtggtcggc tcgtccatca gcaggaggtt gggcggatcc
    10981 actaggaatt tgaccaagct gagccgcgat ttttccccgc cggaaagaac gctgacgcgt
    11041 ttttccacat ccagcctccg gaacaggaag gaacccagga tggaacgcgc ttcttcctcc
    11101 cggatttcag cgctgcattt catgatttcc tccagcacgg tattttccgg attcaggttt
    11161 tccgttcgcg cctgggagaa gtagccgatg cgcgtcgtgg taccgggagt gcgttgtccg
    11221 gagtcaatgg ggatgatgcc cgccaggatt ttgagaagag tggatttgcc cgcgccgttc
    11281 ggacctacaa gaacagtgcg ctccccgcgt tccaccagca ggtccaggtt ttcataaacc
    11341 ctgcggtcgc cataggattg gcagactttt tccagctcaa tgactttctg ggtgctgcgc
    11401 ggaggctggg ggaagttgaa tttaaatacc ttcctgcggg ctaccggttt ttgaatgatt
    11461 ttcatctttt ccagctgctt gatgcggctc tggacttgcc cggctttgga attgatggag
    11521 cggaaacggt caataaattc ctgaatgtgc gctatttcct tctgctggtt gcggtaggcc
    11581 gcctgaagct gctcgaagcg cacgtccttt tgttggagga agtccgagta attgcctcgg
    11641 tattccacca gttcttcgtt gtcgatgtcg tacacgcttt ccaccagctc atccatgaaa
    11701 tcccggtcgt gggaaatcat caggatggct ccggggtagt ttttcaggta tcgctggagc
    11761 cacagcaggg acaggaggtc caggtggttg gtaggttcgt ccagcatcag gaggtccggc
    11821 tccaggacaa ggagcttggc caggtacgcg cgcatgatcc agccgccgga catttcccgg
    11881 gcggggcggt ggaagtcgct ttcccgaaag gccagccctt tgagaatttt cttggctttg
    11941 ggctccagct ggtaaccgtt ggcggcgttg aaggtgtcaa tggcttccgc gtattccggc
    12001 gtatccgttt tgttggcgtt ttccgccgtc cggatggtgt ggatggcctg ttccatttcc
    12061 ggcgtgatgc ccagggcgat ttccaggacg gtttcatcct tcggttcgct ggcttcctgg
    12121 ggaagatagc ccacgatggc gtattcatcc atgctgatgg agccttcgtc cggcgtgtct
    12181 tctcccagaa tcatgcggaa cagggtggat ttgcctgctc cgttggggcc gaccagagcc
    12241 acccgttccc cccagttaat ggtcatttcc gtttccctga acaaggtccg tccggcgtgg
    12301 gattttgtga gatttttgat cgtcagcatg gtgaagagag gatgtattct accgggatgg
    12361 aaaggggaag gcaagagccg tcagggcgga ggcaggcatt tttgaaagct ttactggatt
    12421 tttacgcgta gtctgctagc cttggcgcgc catgccgacc acgcagacat tcaggctttt
    12481 gcttgctgcc gcccttttgt gcggatggag ttcctgctgt actcctccgg cggaggatta
    12541 tatacaacaa ccttacgtgc agcagcaaat gtccgggctg gctaatgcct tcctggcgct
    12601 gctgccgccg gatcaggcct ctcttcccgc tgccggagcg gaggccaggt ggctggcgga
    12661 cacggccgtg gtccagtccg cagcgattgc ccgggacaac aggactgtgc tgtttggctg
    12721 gctgaacaat attctggtca attccaacct gcgcgacagg gggctgtgct ggcaggtcca
    12781 gcaggatttg taccgggacc tgcgccgccg ccccgtgaag tatttccgca tagggctgac
    12841 gattcgagac cgtggaacgg gcagggagca cagttgcgtg tatgtcaatg ccgcggggaa
    12901 gggattgcag ggctccattg ttctggatgc ctggaagaac tgcgggcatc tggtgacgct
    12961 gacccagaag gaccgggaag gcggcaaatg ggaggaggac tggcgggaac catttgtttc
    13021 caaggccttt ccggagggcc attcctacgg catggaacat cacctggtct ggcccgggtg
    13081 ggccaggaaa cgccccatgc tggttcagcg gatatttcag tccgatcagc agaatgaggc
    13141 gaaggcggcc gctgaataaa ggggaagcct gatccggcaa gaaccggcac acggtgctgc
    13201 gccgcggcgg tttgcggtat ccgccgtttt taaggaaaat cccggcgaat cggcaaatgg
    13261 cggagggaat ccggactcag ggcaaataaa aacgcactca gtgcgtacac cgagtgcgga
    13321 ttaattggat aatttgctag tgttgcaggg caaaaccccg ctgcaaactt acttgccctt
    13381 ggcctgcaca accggagcgg gagcaggagc ggtggtttgc tgttgctgct gctgctggga
    13441 gcaagaagcg accaagcaag cggcgccggc gatggcgagg atagcgatgt tcttcataat
    13501 tcgaattaaa tacagtgttt gttaactact ggaacctccg catccacgga ggtttgctgg
    13561 caccaatgta aatggtggca agtagaaatc aagagatttt cttgttccat gtcacggcat
    13621 tacagaaaag agcaggaccc ccggtttctg aagtcctgct ctttttgatg cgt
//
