LOCUS       c00166_gnlPro..         6014 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GFDDHEID_176.
ACCESSION   c00166_gnlPro..
VERSION     c00166_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 20:42:12
            Original ID  :: gnl|Prokka|GFDDHEID_176
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6014
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..651)
                     /locus_tag="ctg166_1"
                     /transl_table=11
                     /translation="MYFNLPKRMINITKLVCVIGVVSVAFSSCLQKDVYDPANSGDKEE
                     EVTLDNYFDFATTKNIQLNIDYGKECPRAYFEVYAENPLSYVAEGGQIIKKAGVSHIAT
                     GFTDIQGRYIKPASFPTTVSEVYIYSPDFGVPTLYKTKIVGSDVSAEITFENALDVTAV
                     DSSTRSAQTRSSLKFITNVIPNVLGTWNVNTGRPNYLDASKKINVDATLKSYIT"
     protocluster    1..6014
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[845:6013]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      846..6013
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..6014
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6014
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(846..1889)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_2"
                     /sec_met_domain="IlvN (E-value: 4.1e-47, bitscore: 148.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4e-42, bitscore: 132.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACEKGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYNSVKTGNEAQISIDSNSQPDYREKLNEELRQLRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(1957..2700)
                     /locus_tag="ctg166_3"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             complement(2706..3263)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_4"
                     /sec_met_domain="ALS_ss_C (E-value: 1.2e-19, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEEVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             complement(3321..5015)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-48, bitscore:
                     152.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIHRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDTDEETVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNTH
                     TEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRVFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             complement(5147..6013)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_6"
                     /sec_met_domain="ILVD_EDD (E-value: 4e-95, bitscore: 307.9,
                     seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="APNTQKYHIQDVNRAGGIIAIMDELAKGGLIDTSVRRVDGMSLAE
                     AINEYSITSPNVSEKAIKKYSSAAGNKFNLVLGSQGMYYKELDKDRANGCIRDLEHAYS
                     KDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEAACEGILGGRVVSGDVV
                     VITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHISPEAAAG
                     GNIGKIVDGDIIEIDIPARKINVRLTDEELAARPMTPVTRDRYVPKSLKAYASMVSSAD
                     KGAVRII"
ORIGIN
        1 tgttatataa ctcttaagcg ttgcatccac attaattttt ttagaagcat ccagatagtt
       61 aggtctacca gtatttacat tccaagttcc taatacattc ggaattacat ttgtaataaa
      121 tttcaaagaa gatcgtgttt gtgcacttct cgttgatgaa tccacagcag taacgtcaag
      181 agcattctca aaagtgatct ccgcactgac atccgaaccg actattttag ttttatacaa
      241 agtcggcaca ccaaaatccg gagaataaat ataaacttct gaaactgttg tcgggaaaga
      301 agcaggcttg atataacgtc cttgtatatc agtaaatccg gttgcaatgt gtgaaacccc
      361 tgctttcttt ataatctgac cgccttctgc cacataagaa agcggatttt cagcataaac
      421 ttcaaaataa gctctaggac attcctttcc ataatcaata ttcaattgaa tatttttagt
      481 agtagcaaag tcgaaatagt tatctaaagt aacctcctct tctttatctc ctgaattagc
      541 aggatcatat acatctttct gcaaacagct ggagaaagca acagaaacaa caccaataac
      601 acatactaat ttagtaatgt taatcattct tttgggcaag ttaaaataca tcatacttct
      661 cgtttatttt atttgatggt gcaaatataa acataaactt gcatatttta gtcatattat
      721 agatatattt ttctaaaaaa agcaatttaa aggattcact cctcctttta tacaatgtat
      781 ttccaataaa aaaggagaga actatttgct ctctcccctc ttaaaacttg tataatttat
      841 ccagtttaat tattctccgg acgaagttta cgaacagtta cagcagtctg ccacatttcg
      901 ctctcgcgta attgacggag ttcttcgttc aatttttcac gataatcagg ttgtgaatta
      961 ctgtcgatag aaatctgtgc ttcattacca gtcttcacac tgttatacaa cttttcaact
     1021 accggtttga tagcatcgtg gaatgggccc atccaatcga gagcaccacg ttgagcagta
     1081 gtagagcagt tagcgtacat ccagtccata ccgttctttg caaacaacgg catcaacgac
     1141 tgtgtcagtt cttccactgt ttcattgaat gcttcagaag gactatgacc gttttcacgc
     1201 aatacttcgt actgtgccag caacaaacct tggatagcac ccatcaatga accacgttca
     1261 cctgtcaagt cagaagtagc ttcacgttgg aaagttgttt cgaacagata accggaaccg
     1321 ataccgatac ctagtgcgat agttctttcg taagccttgc ctgtagcatc ctgatagata
     1381 gcataagaag agttcaagcc acgtccttcg aggaacatag tacgcaaaga tgtacccgaa
     1441 cctttaggag caaccatgat aacgtcgata tcagcaggag gaactacacc tgtacggtcg
     1501 ttccaagtga tagcaaaacc gtgtgagaaa taaagagctt ttccggcagt caggtaaggc
     1561 ttgatagtag gccatactga cattactgct gcgtcagaca acagacacat tacaatagta
     1621 cctttctcac aagcttcttc gataccgaac aaagtttcac ccggaaccca tccgtctgct
     1681 actgccttat cgtatgtttt tccttcacgt tgaccaacga ttacattgaa accgttatca
     1741 cgcaagttca gtgcctgtcc aggaccctgt acgccataac cgattacagc gattgtttca
     1801 tttttcaata cttcacgagc tttttccaat ggaaattcgt cacggattac tacagtttca
     1861 gtagtacctc caaaattcaa ctgtgccatt ttctttttgt ttttagtttt tgatgactta
     1921 cgccatctgt tattaattga ttttatattc tcacatttat tcaaatatca ctttcgagcg
     1981 gcaaacaact tcgttgccat tcttcttcac ttctacgtga aactcgtttg cgttcacttc
     2041 atcgcagaag aaagagagtt catcaccaaa atagctttcc gccacatacg ccatttcaaa
     2101 acgacggata cgtttggtct tatacaattc aatcgggaac aaatcaagga tatgctcgat
     2161 gtaacggatg ctgtttacat gaccgttgat atctatatca ctgtattttg ccgtcagggt
     2221 agctatcggc tgatcgcttg tcactttgat gcgtgaaggc ttttcaatcg ggcaaggctc
     2281 atcacagaca tagtctacga tacttccccc atgcaaagtc aacaagtcgg caggcttgcg
     2341 ggtattaaga ttaatcattg cccatacgga acgtgcgtag ccaatcttct tcccatcctt
     2401 atcaataata gcaaaattac ggtccgtaaa caagcggtag acattttcca cccacgtctg
     2461 aaccgagaaa ttctcatact gataaggcat ttcatccaac tcaatagcca gacgtgaaag
     2521 cacccatgta taattgtcct cattcagcgt tgcaatacca aaaccacggt cattggcgtg
     2581 aaaacctgca caattcagca gatgatttcc cagtaccccc atagtcagac gtccgttgaa
     2641 gtcaacatgg aacggttctg ccacaaactg ataagtccct attctatttt cttcactcat
     2701 tattcttatt ggtttttact ttggttatac atagcttccc gtccatcgag aaactcattc
     2761 acccgttcaa agcagctggt agtaatcgct acacgtcccg aacgaacaaa ctgcaaaaca
     2821 caattcaaag ccttcagttc accatagagc gaagttatat cttcgctcat tccatttttc
     2881 tcgacaatag aaaataccgg attgacttcc actatacgtg cattgtatct acgaatcagc
     2941 ttggatgctt ccggattctc ctgaaaagca ggagtagaca ccttatataa tgcaatctcg
     3001 tggaaataaa tctcatcctc tgtgaaataa tgtgcctgaa tcacgtcgat cttcttttcg
     3061 atctgtttca ctacctcctc aatgatgtcc ttatcagtcc aggctgttat tgtatactta
     3121 tgtacacctt taatagaaga agcagataca ttcagactct caatatttat ttgccgacgg
     3181 gtaaatacag cagttacctg attcagcaac ccagctatat tctccgaatg aacaatgatt
     3241 gtatataacg ttttatcact cataactcta attttttaaa tgcgaactct caactctcca
     3301 ttctcaactc tcaacttctc ctagcactcc agcaacatct ggtttaccga accacccgga
     3361 ggagtcatcg gcaaaacatt gccttcttcc accacgcagg cttcgagcag gaacggaccg
     3421 tccgttgcca gcatttcagc aatagcttcc ttcagttctt cacgagtgaa aacacgcttg
     3481 gaaggaatat cataagccga ggccactttc atataatccg gattcaacat cggggtgaac
     3541 gaatagcgac ggttgaaaaa catagcttgc cactgacgta cgtttccgag gtaattattg
     3601 ttcaagcaga taatcttcac cggagccttc tgctccataa tcgtacccag ttcctgaata
     3661 ttcatttgca gtccgccatc tcccataaat acgcatacgg tacgttccgg tgctccgaaa
     3721 gttgccccga tagctgcggg aagcccgaag cccattgttc caagtcctcc ggaagtaatg
     3781 atactgcgtt ctttcgtata tttaaagtag cgtgcagata tcatctgatt ttgacctaca
     3841 tctgttacca aaacagcttc atggtgagta gcgtcactta ccgcacgtac cacttccccc
     3901 atactcaaag agtttgtggc aggatgaagt tcaggacgga ttactttttc ctcctctact
     3961 ttctcatatt ctttgaagct atcaatccat tcggtatgag tgttcttttt cagaagtttc
     4021 gtcacagaag ccagtgtttc cttgcaatct cccaatacag ctacatctac ctttacattc
     4081 ttattaactt ccgcaggatc gatatcaaaa tgaatcactt ttgcctgttt ggcataagta
     4141 gccaaattac cggtcacacg gtcgtcaaaa cgcataccga cagcaatcag cacatcacat
     4201 ttattggtat tgatattcgg tcccagattg ccgtgcatac ccaacatacc tttattcaac
     4261 ggatgttctg tcggcaaagc cgaaagtccg agcagcgtac aacccgcagg catatccgct
     4321 ttttcgataa actcgcgcaa ttcgctctgt gcatttccca gttcaacacc ttgtccaacc
     4381 aatacaagcg gacgttcagc gttattaatc agttcggcag cagcctgtac agtctcctcg
     4441 tccgtatcgg gaacaggaac ataactacgg ataaaatcga ctttcgtcgg ttcgtatttc
     4501 gttttctcta cttgcgcatt tttggcaaag tccaatacca ccggccccgg acgaccacta
     4561 cgagcaatgt aaaacgcacg tgctaccgcc caggctacat cttccgcacg gtgaatctga
     4621 taactccatt tagtgattgg ctgggtgata cctaccaagt caacttcctg aaaagcatcc
     4681 gtcccaagaa agcctgttcc tacctgtccg gcaatcacca cgataggcgt actatcgatc
     4741 atcgcatccg caatgcctgt taccgtattg gttgctccgg gaccgctcgt caccaggcaa
     4801 acacctacat cacccgatac acgggcataa ccttgtgcgg catgggcggc tccctgctcg
     4861 tgacgaacca agatatggtt caatatattt tgatgatcgt acaaggcatc gaataccggc
     4921 ataatagaac caccggggta accaaagatg gtagtcactc cctgatgttc caaggagcgc
     4981 atcaaagcct ctgcacctgt tattaaatct ttcatattag ttgatagttg ataaatgata
     5041 aatgataaat gatagttgag aaatgacagt tgaaaatgaa tggtttacaa tcattgcgct
     5101 aagtgctgcg cagctaacta ttacctatca actatcacca actatattat ataattctca
     5161 ctgctccctt atcggcagag cttaccatgc tggcatacgc cttcaggctc ttcggtacat
     5221 aacggtcacg agtgacagga gtcatcggac gggccgccag ttcttcatcc gtcagtcgca
     5281 cgttaatctt ccgggccgga atatcgattt cgataatgtc tccgtctaca atttttccga
     5341 tattgcctcc agctgccgct tcaggagaaa tatgtccgat actcaatccg gaagttccac
     5401 cgctgaaacg tccgtcggta atcaaagcac attcttttcc gagatgacgg gattttatat
     5461 aagaggtagg ataaagcatt tcctgcatac cgggaccacc cttcggacct tcgtgcgtaa
     5521 tgacgacgac gtcgccactg acgactcgac ctccgaggat accttcacag gctgcttctt
     5581 gcgaatcaaa tactttggca ggtccggtaa acttccagat actttcgtct acacctgctg
     5641 tttttactac acaaccatct tgagcaatat tgcctttcaa tacggccagt ccgccgtctt
     5701 tgctgtaagc atgttccaag tcacggatac atccgtttgc acggtcctta tccagttcct
     5761 tatagtacat accttgtgaa ccaagtacga gattaaattt atttccggct gcgctcgaat
     5821 atttcttaat tgctttttcg ctcacattcg ggctggtgat tgaatattcg ttaatggctt
     5881 ctgccagtga cattccgtct acccggcgaa cggatgtatc tatcaaaccg ccctttgcca
     5941 gttcgtccat aatggcaatg ataccaccgg cacggtttac atcctgaata tgatatttct
     6001 gtgtattggg agcc
//
