LOCUS       c00215_gnlPro..        24557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GFDDHEID_243.
ACCESSION   c00215_gnlPro..
VERSION     c00215_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 20:42:12
            Original ID  :: gnl|Prokka|GFDDHEID_243
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 34351
            Orig. end    :: 58908
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24557
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[44351:48908]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14557
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24557
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24557
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             468..662
                     /locus_tag="ctg215_27"
                     /transl_table=11
                     /translation="MKKTELALLYMPYASADVARRHLNKCIRRNRELLEALEATGWAFW
                     IHWLTPLQVELIEKYLGEP"
     CDS             complement(666..2465)
                     /locus_tag="ctg215_28"
                     /transl_table=11
                     /translation="MDRFKELGIDTHGRTSGKMKTKCPWCHAQRTDKRDKSLSVNLDTK
                     LYLCHYCGAHGSAAIYAGKGRKLGDPLVKFPTATGSNSSCPPTEKPHGDPEQGALTQKQ
                     IEWCRDVRHIPPEVLVEAGVAFASISMPISGKEKGWEKRDCLCFNFFENGELVNTKFRD
                     SQKHFKLLQGARTIPYNIDAIRDTPECILVEGEFDALSYMAVGRTDVISVPNGANSQLD
                     WLDELSESHFEQKQVIYLSVDTDRKGRELCRELSRRLGVDRCRIVTYGEAYKDANELLV
                     AEGPDALLKALEDAPIPRLEGTFTAEDLRERLHQLFEEGYTSGVELGIPNLDEIMRLET
                     GRVLTVTGIPGHGKSDFVDEIVLRLCTRQDWRAGYFSPENTPIEYHHAKLAEKLLGHRF
                     RKDFSTEEEFARVVDYLSQRVWHILPDGDFTLGNVLSKARELVHRHGIRVFVIDPYNYI
                     NHQIPAGMTETGYIGSFMNSLARFARLNSCLVILVAHPRKMNKQYGTQKTEVPTMYDIN
                     GSANFFNMTDYGIVVDRQDEMGIVYIHVEKTRFRNFGTKGNAAFCYDVTNGRYSPCTPP
                     PEPGMQVQPWKGAKDLFSSEGWI"
     CDS             complement(2494..3798)
                     /locus_tag="ctg215_29"
                     /transl_table=11
                     /translation="MTTSNSANTKQSNNASQKRKPIHNGYFNHPTSSSSNIPMSILIRE
                     QGLEIYGLYWVMLEEAHAQLKCCVNIQTMEIIANIFHAQPEHLELLYHHYFRRPGKGYN
                     SHILYADFCEESAIRSYFPHPLLAYTDNELLRMIMQDGLKAYGLYWLVMEKLYQQPQHF
                     LAPQTASFIQNLYDVSDELMESVLYNYGLFYLDEKMNLHSKAIDDYREALDNMEDEKKR
                     NTKPHVNNSLKANGNAEDFNTREMKKTSNIQKNPSPIINKEINKKNSSSEENGKEKEEE
                     NGLKVTDLNAVTPDMRPNAWEENLQEAMNDTSWYEVVAIQSGIPRLMMEEKEWFFNYLR
                     EQIILRGNESSMNSLHEIKNYFANLTRQGSHVSSTTQVALKRFLKNRQEQQQCSPYETI
                     TNGIRTYDGHPIPAYAKPRPSAAHIWNPVTNEWTR"
     CDS             4131..4547
                     /locus_tag="ctg215_30"
                     /transl_table=11
                     /translation="MKLIFFHRRAEYNPCHSTRKPFSTMHVIVWEKPVGGVFVVGAAEI
                     VFIFCQCPCNGKAGSVCSLQAEIGVVPSHPVYQFFYLVCTAHRFSQCQQCAVILFRILA
                     DNSCPTGNRQATVILHRFFHTDFLVLKCSHFSSC"
     CDS             complement(4810..5241)
                     /locus_tag="ctg215_31"
                     /transl_table=11
                     /translation="MPKWISVEKAVIKYHIEKEAILLWVEMGQFPMLYIDNVPNVDEEC
                     ILELFRRSKAGITAEYIDTLEQLCIDKTMVCEKYAHIIQLKEKEIQLQKEINTLINEIQ
                     AAMKRQNERIRDLKKAIGENNNVIRSDSWIKRLRKRFQW"
     CDS             5508..5621
                     /locus_tag="ctg215_32"
                     /transl_table=11
                     /translation="MLIYDYLRGVSVVSSLGVKKLLIFKFERQYVIYSIKE"
     CDS             complement(6228..6635)
                     /locus_tag="ctg215_33"
                     /transl_table=11
                     /translation="MEITDLKQMTKEEVFNFIRQRLSFSKELQEQFRHVNKDDLAKEHR
                     RFEMSGNESKTGQCTIFNTAILNEFADLGIYDYTSYLFLDFHNGTPTVYLKYFSENENL
                     EYTFTGYTTTEIIFAILELTIFSGKPKRNRS"
     CDS             6829..8043
                     /locus_tag="ctg215_34"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIYLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRIPRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             complement(8124..8378)
                     /locus_tag="ctg215_35"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             8812..9816
                     /locus_tag="ctg215_36"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAQ"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg215_37"
                     /sec_met_domain="OAD_beta (E-value: 5e-153, bitscore:
                     501.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLVFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFVIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11163..11594)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg215_38"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.9e-21, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             complement(11619..12539)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg215_39"
                     /sec_met_domain="OAD_gamma (E-value: 4.9e-15, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQNNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             complement(12571..14124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg215_40"
                     /sec_met_domain="CT_Btheta (E-value: 1.4e-289, bitscore:
                     953.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(14153..14557)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg215_41"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.3e-23, bitscore:
                     75.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAEGKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(14733..15731)
                     /locus_tag="ctg215_42"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNAFHSKELFQIYEATPGYTPLLIVA
                     TEDGRPVARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEVFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRI
                     RQIKKGLKNGARVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNNMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSGDDAYLWFSGGMRKTYALQYPGVLAVWKALEDAHQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRVNWSWLNKLLVKFYV"
     CDS             15971..18415
                     /locus_tag="ctg215_43"
                     /transl_table=11
                     /translation="MRCNAFVEAWKNYHRRASMILGLSLLAAPLSYAVYAEDGVSNTMV
                     QVVTQTKTVKGTIIDESGEPLIGVSIVVKGTSTGTITDFNGNFSIDLPAGRKELVISYI
                     GYKEQTVTVTGNGPVNVKMVSDTQALDEVVVVGYGTMKKRDLTGAITSVKSEDVVMNPS
                     SNPMQALQGKVAGLDITRESGQAGSGVKMQLRGNRSFQKDSGNPLFIIDGMPGDYSTLN
                     PNDIESIEVLKDASSTAIYGSSGANGVILITTKGGKEGKAIVNFNAYVGVNGWSRTPEM
                     RSGESYIQTLRDASVGAGDGRWSSVADDKNLFTTDAEWSAHQNGQYIDWVDALLKTSVT
                     QNYSVSVAGGTEKTKAYFSLNFSNEDGQFAQDSYKLYSSKIRVDHKIKKWMKVGIDAQL
                     SYVHQNKADSDLQTLMASNPLGSLYNEDGSINPQPVADPSSTVYNYLLNEDKSLYRNQA
                     QNLKVYFNPYLEITPLKGLTFITRAGASLGYSRSNTFTGEGSVQWYKANQTADGIKAQV
                     KDNRSYNYKWENILTYNFQIKKVHDITLTAVTSWNHNRSDVTTLYQKGVSDNKFLWHNI
                     LDGNSATSGSTSYSMSKGMGYVGRLNYSYMGRYLFAASVRHDGSSRLAEGNKWDTFPAF
                     SLGWRISDEKFMESTTNWLSNLKIRFGYGVTGSTAGIDPYSSAASLDATAVNMILGGVL
                     TPIYKFSQNIPNYLLTWEKSYNTNIGIDAAFLNNRIDVSMEYYNTKTKDVIWNKALPVI
                     NGAFSPDGGPKANYTTNLNMCETSNKGFELALNTRNIITKNFTWSSSXXXXXXXXXXGV
                     QV"
     CDS             18448..19251
                     /locus_tag="ctg215_44"
                     /transl_table=11
                     /translation="LSGGDSDVLNNGDTGYALALGEAINSYYHYKLDGVWQKGEETDAA
                     VFGAAPGDLKINIPNLVKESDGRFYKIDEETGSAAVDENGNVIYYTSDNKYTPSDADYQ
                     ILGHNSPDWSLGFQNNFTWKDFDLSVFVYARYGQMFAYDMLTSYDPKGIRNFPTYFNYW
                     TENNPSNDFPAANANKGLEQYTGYYALRYVDGSFIKIKNITLGYSLPKSILKSAGIEKC
                     RFYATITNPFVFAKSHLLKDYDPEMNGSLKYPLTKQFVFGVNVTF"
     CDS             19276..21300
                     /locus_tag="ctg215_45"
                     /transl_table=11
                     /translation="MKSTIYKIAALTFAVASMSACSLDEYNPSQKTGDEILATFDGLKG
                     LQSYCYSSLYGQLFSVYDFLSVAEGGTDCWITPAGNPDYAKQVIYYDGLATNTNATNKL
                     FGQAYSMIGNCNAVVNRAELLTDGNEKDITTLVAEARCLRAFYYSILVNTYGNVTLTLE
                     ESSQDPILTPQRNSIEELYTQIIDDLKFAANNLEDTPYDNNRARVTKKTALGLLARVYA
                     QGGGEYGLTEEGVSYWQRAKEVAEDMILAYGDCLYDDVEDVWAPANNRNNKEALFIAAG
                     PDATNLENWNAGTQCNNNFTYMYPKPNTLTIYPTPDNQNYWYGRTNNNTLAPSKYLLDC
                     FDADYDKRWEVTFTTAFVQFSAVQSGGSYLFTNKKQTLDDGTKPKIGTKHGVNDNISSF
                     TILTQNIIDTYGLDAKFHNEYIYPYGDLNYTYYDGTWAPKMIAKVWPKGENSGDPSKLQ
                     EVKNPYVIPYPVAEDDDRICFYLSKERLSDAEKAKRRYYVINIDDLFDNGQYRKTDIKV
                     TNDKNMYPGFNKYNWLSEDSYSSNLQRKTGDVFIMRMAEVYLIAAEANQQLGNGGKAAE
                     YLNVLKKRAARNDASYNAMKLSNATQNDVMDEYARELCGEYQRWVLMKRHKDSFKQRLA
                     VGNPRAAENFDENKHYLRPISFNFLSQIDNAEEYGNNGY"
     CDS             21410..21952
                     /locus_tag="ctg215_46"
                     /transl_table=11
                     /translation="MIEEILAYNKQFVENKGYESYITNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     ETMLEKMTARGINPDYIDMMRFCGVDFHVWLNGFEDTEKSVRGTVDFIVRHPLIPSDVT
                     VYGFIIDSTTGELTRIV"
     CDS             22298..22834
                     /locus_tag="ctg215_47"
                     /transl_table=11
                     /translation="MENFSELIKNRRSMRKFTDEELTQDQVVALMKAALMSPSSKRSNS
                     WQFVVVDDKEVLKELSHCKEQASSFIADAALAIVVMADPLASDVWIEDASIASIMIQLQ
                     AEDLGLGSCWVQVRERFTATGMPSDEFVHGILDIPLQLQILSVIAIGHKGMERKPFNEE
                     HLQWEKIHINKFGGK"
     CDS             22837..23172
                     /locus_tag="ctg215_48"
                     /transl_table=11
                     /translation="MGAAKANNSKDTYLATAVTFIVIGALYLIDKLIHFSSIGLPWVMN
                     KDNMLLYASICFLIFKRDKSIGFVLLGLWLVMNIGLVMSLLGSLSGYLLPLTLLIIGIV
                     LFWFAKR"
     CDS             23180..23974
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg215_49"
                     /sec_met_domain="F420_oxidored (E-value: 1.8e-13, bitscore:
                     43.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTMESAR
                     TLAEKVEAEYTTDLQAVSKDAKLYIVSLKDDALVDLLPQITEGKQASLLVHTAGSIPMS
                     VWEGHAERYGVFYPMQTFSKQREVKFQEVPFFVEAKRPEDVELLKAVAATLSEKVYEAS
                     SEQRKSLHLAAVFICNFTNHMYALAADLLEKYNLPFDVMLPLIDETARKVHELAPRDAQ
                     TGPAVRYDENVMSNHLAMLVDSPALQEIYKLMSKSIHEHHQL"
     CDS             23955..24476
                     /locus_tag="ctg215_50"
                     /transl_table=11
                     /translation="MSTINYDLSRIKALAFDVDGVLSSTTVPLHPSGEPMRTVNIKDGY
                     AIQLAVKKGLHIAIITGGRTEAVRIRFEGLGVKDLYMGSAVKIHDYRAFRDKYGLTDDE
                     ILYMGDDVPDIEVMCECGLPCCPKDAVPEVKSVAKYISYADGGRGCGRDVVEQVLKAHG
                     LWMVEDAFGW"
ORIGIN
        1 gcccaatcct tcgagcttca ctgtccggct gttgagcaac tgctcgcgca tcactgccat
       61 caggtttcgg atcacgttgt gcacgtcacc ggccgtcagt gatgaccgtt cggcaatcgt
      121 ttcgccaatc atttgcgtat ccactacgtt tcccatttta atcaggcagg gatgccattt
      181 cttctttttg tccttcgatg cgatattgga ctgaaccgct ttgtaaatca acatactgat
      241 ttcctccttt ttaagtgaat aaataagatt ttattgagtc agtaaacgaa cgttttctgt
      301 ctcttttaca gtagcaaaga taccccaacc ggcaggggag gaaacatgaa acggtatctg
      361 ccggtaagtg aaggcaaacg cttgaatatc tgtgtatttg cttgcatttc tacgcaaaaa
      421 acagtatctt tacatgacgt aaataataaa ttaaaagaag aaaatctatg aagaaaacgg
      481 aattggcatt actctatatg ccgtatgcaa gtgccgatgt ggcaagaaga catttaaata
      541 aatgcatccg ccgaaaccgg gagctgctgg aggctctcga agctaccggc tgggcgtttt
      601 ggatacattg gctcacaccg ttgcaggtgg agctgattga gaagtatttg ggagagcctt
      661 aatccctaaa tccatccctc tgacgagaat aagtctttgg ctcccttcca cggttgcacc
      721 tgcatgcccg gttcgggtgg cggcgtacaa ggggaatatc ttccgttggt cacatcgtag
      781 cagaacgctg cgtttccctt tgttccgaaa ttacggaaac gggttttctc gacgtgtata
      841 tacacgatcc ccatttcatc ctgacggtct accactattc cgtagtccgt catgttgaaa
      901 aagttggccg agccgttgat gtcatacatg gtgggaactt ccgttttctg cgtgccgtat
      961 tgcttgttca tctttctcgg atgcgccacc agaatgacga ggcaggagtt gagccgggca
     1021 aaacgtgcca gactattcat gaatgaaccg atataccctg tctccgtcat gcctgccggg
     1081 atctgatggt tgatgtaatt gtacgggtcg atgacaaaca cacggatgcc gtgacggtgt
     1141 accagttcgc gtgccttcga caagacgttg cccagtgtga aatccccgtc cggaagaatg
     1201 tgccagacgc gttgcgaaag ataatccact acgcgggcga attcctcctc cgtagagaaa
     1261 tctttgcgga aacggtgtcc cagcagtttt tccgccagtt tggcatgatg atactcgatt
     1321 ggcgtgttct ccggactgaa atatcccgct cgccaatctt ggcgggtgca gagccggagc
     1381 actatctcat ccacaaagtc cgatttgcca tgtccgggaa taccggtgac ggtgagcacc
     1441 cgccccgttt ccagcctcat gatttcgtcc agattcggta ttcccaattc cacgcccgaa
     1501 gtatacccct cttcaaacag ttggtgcaac cgctcccgta agtcttctgc cgtaaacgta
     1561 ccttccaggc gggggatggg tgcgtcctcc agtgccttca gtagtgcgtc cgggccttcc
     1621 gccacgagca gttcgttggc gtccttgtat gcttcgccgt aggtgacgat acggcagcgg
     1681 tctaccccca gccgtcggga gagttcccgg cacagttccc gtcccttgcg gtcggtgtcc
     1741 accgacagat aaatcacttg tttctgctcg aaatgagatt ccgacaattc gtccagccag
     1801 tccagttgac tgttggcacc gttcggcacg gaaatgacat ccgtccggcc gacagccatg
     1861 taggagaggg catcaaattc cccttccacg aggatgcact ccggcgtgtc gcggatggcg
     1921 tcgatgttgt aagggatggt gcgcgctcct tgcagtaatt tgaaatgctt ttgtgagtcg
     1981 cggaacttcg tgttcaccaa ttccccgttt tcgaaaaagt tgaagcagag acagtccctc
     2041 ttttcccagc ctttctcctt tccggatata ggcatcgaga tggaggcgaa agccacgcca
     2101 gcttccacca atacttccgg cggaatgtgg cggacgtcac gacaccattc aatttgcttc
     2161 tgtgtgagtg ccccttgctc tgggtcgccg tgcggctttt cagtgggcgg acaactggag
     2221 ttgctacctg ttgccgttgg aaatttgacc aacggatcac ccagctttct gccttttccg
     2281 gcatatatgg ctgccgaacc gtgtgcgccg cagtagtggc acaaatacag tttggtatcg
     2341 aggttgacac ttagtgattt atcacgctta tccgtccgtt gggcatgaca ccagggacat
     2401 tttgttttca ttttgccgct tgtgcgaccg tgggtatcaa tacccagttc tttgaatcta
     2461 tccatattta gtaaatgatt gagagataat atgctatcgt gtccattcgt tcgtcaccgg
     2521 attccagata tgtgccgccg aaggtcgcgg cttggcataa gcggggatgg gatgcccgtc
     2581 gtaggtacgt attccgttgg tgatggtttc gtagggcgaa cattgctgtt gctcttgccg
     2641 gtttttgaga aacctcttca gtgccacctg cgttgtggat gacacatggc ttccctgccg
     2701 ggtgagattg gcgaaatagt tttttatttc gtgcaggctg ttcatcgagc tttcattccc
     2761 ccgtaagatg atttgctccc gtaaatagtt gaagaaccat tctttttctt ccatcatcag
     2821 ccgggggatg cccgactgaa tggctacgac ttcataccag gatgtgtcgt tcattgcctc
     2881 ctgtagattt tcttcccatg cgttggggcg catatcgggt gtcacagcgt tcaagtccgt
     2941 caccttcaaa ccattttctt cttctttttc ttttccgttt tcttcagaag aagaattttt
     3001 tttgtttatt tctttattta taatggggga tggatttttc tgtatatttg acgttttttt
     3061 catttcccga gtgttaaaat cctctgcatt tccgttggct ttcagagagt tattgacgtg
     3121 cggtttcgtg ttgcgctttt tttcatcttc catgttgtca agtgcttccc tataatcgtc
     3181 tattgcttta gaatggaggt tcattttctc atccagataa aagagtccgt aattgtataa
     3241 tacactttcc atcagttcgt cgctcacatc ataaaggttc tggatgaagg aagcagtttg
     3301 cggtgccaga aaatgttgtg gctgttgata gagcttttcc atcacaagcc aatatagtcc
     3361 gtaggctttt agtccgtctt gcataatcat ccgcagcagt tcgttgtcgg tgtatgccag
     3421 tagggggtgc gggaaataac ttctgatggc agattcttcg caaaagtcgg catagagtat
     3481 atgcgagttg tatcctttgc cgggacgccg gaaataatgg tggtagagga gctcaagatg
     3541 ttcgggttgg gcatggaata tattggcgat gatttccatt gtctggatat tgacgcagca
     3601 tttaagctgt gcatgagctt cttcgagcat cacccagtat agtccgtata tttccagtcc
     3661 ttgttcccgt atcaaaatac tcatgggtat attgctggaa gaagaagtgg gatgattgaa
     3721 gtaaccgtta tgaatcggtt ttctcttttg tgatgcgttg ttcgattgtt tggtatttgc
     3781 tgaattagat gttgtcataa taaaatatat tagtttctgt tttaaattct atttttctga
     3841 aaatacagat acgaagaatc cggccacttc tttggaaagt agcaaatatc gtactcattc
     3901 ttcatgatgg aatcggagta ttctcttcgt gtatgtaatc tgtaatatag ggaattttcg
     3961 gagcagggga gatttaattc cgaagttctg aaaaagcaat gctggaaaaa cagataactg
     4021 cctctgtcaa aaaacaagga agcagcattg acatgatttt ttctcttact tgcggttgca
     4081 aagtaactac tttatttcgt atatgtccta caactttcct tatttaatcc atgaaattaa
     4141 ttttttttca cagaagagcc gaatacaatc cctgccactc gacacgtaag ccattttcta
     4201 caatgcacgt catagtatgg gagaaacctg ttggaggggt tttcgtagta ggggcggccg
     4261 aaatagtgtt catattctgt cagtgtccct gtaatggaaa ggcaggttcc gtctgttcgt
     4321 tgcaggcaga aatcggcgtt gtcccatctc atccggtcta tcagttcttc tacttggtat
     4381 gcacggcgca tagattctcc cagtgtcaac agtgtgccgt aattctcttc cgcatcttgg
     4441 cggataatag ctgcccgacg ggaaaccgtc aggcaactgt cattcttcat cgtttttttc
     4501 atacagattt cttagtgctg aaatgctcac atttcagttc ttgttagtgg tgtaaatgta
     4561 gtgaatttac ttgactttac aaaggataaa attacttata taatggatga ttagttaaat
     4621 aaatggaata aaatattttg tatttttcat tgtctgaata taggctttaa agagcttatg
     4681 gaggagttta aagaaagctg tggagggaat ggaaataggc tgcaaagggc aaaggacggc
     4741 cctccttatc ctctgtggtg aaaaccgtgc aataatgtcc cacatggtaa ttggtacact
     4801 gataattatt caccattgaa accttttgcg cagccttttt atccaactgt cactacgtat
     4861 aacgttgtta ttctctccaa tcgctttttt caaatcccgg atccgttcat tttgtctctt
     4921 cattgctgcc tgtatttcgt ttatcaacgt atttatttcc ttctgcagct gaatttcctt
     4981 ttctttcaat tgaataatgt gggcgtattt ctcgcagacc attgttttat ctatgcacag
     5041 ttgttccagc gtatcaatat attctgctgt aatgccggct ttacttcggc gaaagagttc
     5101 cagaatacat tcttcgtcaa cattcggaac attgtctatg tataacatag ggaattgtcc
     5161 catttccacc caaagcagga tcgcttcttt ttcgatgtga tacttaatca ctgctttttc
     5221 tacactaatc cattttggca tatcgctttt gttttaatgt gttataaaaa aggagtaaat
     5281 aacgtattgt ccggagaggt gcaacgaaca cccacgattt ttatgatttc ggtcggctgg
     5341 ggaattggtt ggggtataag gattgttgaa accgaccgga tacaataaaa gcgtgagtgc
     5401 tgttgtacca ttatctaaac ttaaggctta gcaacaccct tcaccagata atgataaaca
     5461 acagacaccc acgccaaacg tttatatata acaaatctct aatcgatatg ttgatatacg
     5521 actatctacg tggagtatct gttgtatcat ctctcggtgt gaaaaaactg ctaattttta
     5581 agtttgagag acaatacgtt atttactcca ttaaggaata aaaaaacgct tttgcctgtt
     5641 tcatcacgct gatgggcaga aagcgtgtga caaagatata tgtttttttc ggaataggat
     5701 ggaaaagagg aaataaatgc aggaaatatg gtatgagaat agagagtatt gtccggagag
     5761 gtgcaacgaa cacccacgat ttttatgatt tcggtcgggt ggggtattgg ttggggtata
     5821 aggattgttg aaaccgactg gatacaataa aagcgtgagt gctgttgtac cattatctaa
     5881 atcgaggtct tagcataccg tgcaccagat aatgataaac aacagacacc cacgccaaac
     5941 gttttatata acaaatctct aatcgatatg ttgatatacg atcatctacg tggagtatct
     6001 gttgtatcat ttcccggtgc atgaaatttg ctaagtttcg atttgggaaa caatacgtta
     6061 tttactccat gaaggaataa aaaccgcctt cgcctgtttc atcacgctga tgggcagaaa
     6121 gcgtgtgaca aagatatatg ttttttcgga ataggatgga aaagaggaaa taaatgaaag
     6181 ccataaaagt cttttgacct cgcattgtct ttccgtgcaa ttctttttta gctgcgattt
     6241 cttttgggtt ttccggagaa gatagtcagt tcaagaattg caaagatgat ttccgttgtg
     6301 gtatatccgg taaatgtata ttccaaattt tcattttcgg agaagtattt gagataaacg
     6361 gttggagtgc cattgtggaa gtcgagaaaa agataagaag tataatcata gatgccaaga
     6421 tcggcaaact cgttcagaat cgctgtgttg aaaatcgtgc attggcctgt ctttgattca
     6481 tttccggaca tttcgaatct gcgatgttct tttgcgagat cgtctttatt cacatgtctg
     6541 aattgttctt gcagttcttt actgaaagaa aggcgttgtc tgatgaaatt aaaaacttct
     6601 tcctttgtca tttgttttaa atcggttatt tccatttttt attaattagt cgggtaaagg
     6661 tactttcttt atttggtaat aaatcggatt tagtcatatt tcttttattt atttttcggc
     6721 ttataaccct aaaagaatct gaatttatgg atttatttag ggttataacc ctaaaaactt
     6781 tcagaaaata gtatatcttt gtgcttataa ccctaaaaac ttttgaatat gattaatcgt
     6841 gaacagtata tggaacaaat tgttcctttt atagataagc cgtttgtaaa agtgataacg
     6901 ggtattcgtc gcagtggaaa gtcggtagtg ctgcgtctga ttcgtgacga actgttgagg
     6961 agaggagttc gtgaagaacg tatcatctat ctgaattttg aaagttttca gtggatagat
     7021 ctgaaagagg cgaaggcttt gtatgcttat attcggggac aggcgggaga tgcgggtaaa
     7081 tattatattc tcttggatga aattcaggaa gtggacggtt gggaaaaagt ggtcaactca
     7141 cttctggtag atttggatac ggatatttat gtgaccggct ccaactcacg tatgttatcg
     7201 tccgaactgg caacttattt aacgggacgg tatgtcgctt tccatgtcat gaccttgtct
     7261 tttagagaat atctgacttt ccatgacttg caggccaatg atccgacgct caaccggaag
     7321 gaggaatttc agaaatatct ccgtatggga ggatttccgg ccatacatac tgccgattat
     7381 ggatatgagg ctatctataa aattgtctac gacatctatt cttctgtcat tcttcgtgac
     7441 acggtgcagc gtcacaatat ccggaatgtg gaattgctcg aacgggtagt gaagtttgtt
     7501 tttgataata taggcaataa gctgaacgct aaaaatatag ctgattactt caaaagtcag
     7561 caacggaagg tggatatgaa taccatctat aattatctga atgcattgga aagtgctttt
     7621 atcattcaac gtattccccg gtatgatatt aaaggaaagg aaattctgca gacgaatgaa
     7681 aagtattttg taagtgacct ttctttgatt tattccgtga tgggctatcg tgaccggttg
     7741 attgcaggta tgttggagaa tctggtctgt ctggagttga aaagaagggg ttatgaagtg
     7801 tatgtaggca aacaggatga taaagaagtg gattttgtag ccatccgtcg ggaagaaaag
     7861 atttatgtgc aagtaacgta tcagttagct tcacaggcca ctgttgagag ggagtttgct
     7921 cctttgctcg ccattaacga ccattatcct aaatatgtag ttagcatgga cagcttgtgg
     7981 caggataatg tggagggtgt caggcatcgt catatagccg atttcttgtt ggatgatgct
     8041 tgacgttaag gaatatagaa aacgaaaaag aggaaattct ctgcgagaat ctcctctttt
     8101 ttcatctttc acgaaagatc gaattatttc ttcttacggt caccgtaacg gctcatgaac
     8161 ttatcaacac gacctgcagt atctaccaat gtagatttac ctgtatagaa cgggtgagaa
     8221 gtgtttgaga tttcaatctt cagcaacgga taagtttcac cttcgaattc gatggtttct
     8281 ttagttgcta cagttgatct agacaaaaac atgtcaccat ttgacatatc tttaaatact
     8341 accggacggt atgattctgg atgaaggcct tttttcattt cagtatctgt ttttttaatt
     8401 tatattctgt tactattttg gtaagaaata gtgtaatggt cattttcaga gcgcaaagat
     8461 aatgcttttc tgtgaaatag aaaaaggttt tctaaaattt ctgatttcta atttatgatt
     8521 tctgatttgc tatgcagatt ttggtgatta aatgaatgaa aaatgaggta taaataaggt
     8581 ataaataagg agatataaat ccgaaggcat caatcagaat tcagaaatca taaatcccaa
     8641 agtttgcaag gtggacatta caatctaatg tcacactcgt attcctgcta aattttgcag
     8701 tctgatttaa acctttttct actatatttt tctttccgat gttcgttatt cgatggataa
     8761 tgcttacttt tgcgtagaat ttttattcac taacaataaa ctttaaacaa aatggtaaat
     8821 tacaaagatt taggattggt aaacacaaga gaaatgtttg ctaaggctat caaaggtgga
     8881 tatgctatcc cagcattcaa cttcaacaat atggaacaaa tgcaggctat catcaaggct
     8941 gctgttgaaa ctaaatctcc tgtgattctt caggtttcta aaggtgctcg tcagtatgct
     9001 aacgctactt tgttgcgtta catggcacag ggtgctgtag aatatgctaa agaattaggc
     9061 tgcgcacatc cggaaatcgt tcttcacctt gaccacggag atacattcga aacttgcaaa
     9121 tcttgtatcg attcaggttt ctcttcagtg atgattgacg gttctcatct tccttacgaa
     9181 gaaaacgtag cattgactaa gaaagttgtt gaatacgctc accagtttga cgtaactgta
     9241 gaaggtgaac ttggcgtatt ggctggtgta gaagatgaag tttcttccga ccatcacaca
     9301 tatactgacc ctgaagaagt aatcgacttc gctactcgca ctggttgcga ctctttggct
     9361 atctcaatcg gtacttctca cggtgcttac aagtttactc cggaacaatg ccacatcgac
     9421 ccgaagactg gccgtatggt tcctcctcca ttggctttcg aagtattgga cgctgtaatg
     9481 gaaaaacttc cgggattccc tatcgttctt cacggatcat cttcagttcc ggaagaagaa
     9541 gtggaaacta tcaacaaata tggtggtgca ctgaaagctg ctatcggcat tccggaagaa
     9601 gaattgcgta aagctgctaa gtctgctgtt tgcaaaatca acatcgactc tgactctcgt
     9661 ctggctatga ctgctgctgt acgtaaggta ttcgctgaaa aaccggctga attcgaccca
     9721 cgtaagtatc ttggtccggc tcgtgacaat atggaaaaac tgtacaagca caaaattctg
     9781 aatgtgctcg gttctgacaa caaattggca cagtaataat ctccggatta ttccataaat
     9841 aaaagaaaga ggctgctccg gtttgaacac tggtagcagc cttttttatg acgtttaatc
     9901 gtttcagaac ggagagaaga taacactatg gctgtaataa agaacacccg tgtcacaact
     9961 gaatgtaaca cgggtgttct tatctattat ataatgtttc ttacatcaag aatccaagca
    10021 gaataccggc agcaacagct gaaccgatca ctccggcaac gttcggaccc atagcgtgca
    10081 tcagcaaata gttggtcgaa tcgtattcca aaccaatcac ttgcgagata cgtgcagagt
    10141 cgggaacagc agaaacacct gcattaccga tcaacggatt gatcttatta cccttcttca
    10201 ggaagatatt gaagatctta acgaagatga caccggaggc agttgcaata acaaatgaca
    10261 atgcaccgag ggcaaagatc ttgatagagt cgagcgtcag gaattcggat gcttgtgtag
    10321 aagcacctac tgtcagaccc aacaggatag tgattgtatc aatcaacgga ccactggcag
    10381 tattagccaa acggcgggtt acaccacttt ctttcaacag gttaccgaag aacagcatac
    10441 ccagcaaagg cagaccggaa ggaaccagga aacaagtcag caacaaaccg atgatcggga
    10501 aaatcacttt ctccgtgtga gaaacggcac gcggcggttt catgcggatg acacgttcgt
    10561 tcttggtggt gagcagacgc atgataggcg gctgtatcac cggaaccaac gccatatagg
    10621 agtaggcgga caccgcaatg gctcccatca ggttaggtgc tagcttggaa gaaaggaaga
    10681 tggccgtcgg gccgtctgct ccaccaatga taccgatagc accggcttgc atcggatcga
    10741 agcccatttc tagcgcgatc atataagcac cgaagatacc gaattgtgca gctgcaccga
    10801 tcagcatcaa ttttggatta gagataagtg ccgagaagtc cgtcatggca ccgataccca
    10861 aaaagatgag tggcggatac cagccggagg tcactccctg atacaatata ttcaatacag
    10921 aaccttcttc ataaataccg actttcagcc cggcatccat attaaaaggt atattaccga
    10981 tcaatatacc gaaaccgata ggaatcagca gcatcggttc gaactctttg gctattgcca
    11041 aatagatgaa taccaagcca acgagaatca tgactacatg ccctaccgta gcattggcaa
    11101 agcctgtgta tgtccagaag tcggctaggt tatttcctaa aaagtttata aagtctccca
    11161 tattattcaa taattacgag gtcattacct tcaagaacag agtctccctt gttgacgttg
    11221 atggcagtaa tcttaccgtc cttatccgca ttgatattgt tttccatctt catggcttcc
    11281 aatatgataa tggtctgtcc tttctttaca gtatcgccta cattcacttt gatgtcgagg
    11341 atcacacccg gcagcggaga ttttactcct gattttccgg tagatggagc ggtcggtttc
    11401 actacttgag taggagcagc aggagcatta ggcatcgggc gtactgtcac gggtttcgca
    11461 acaggcttcg gctgtttctc catttctact ttatagtgtg taccgttcac ttctacatga
    11521 gcgatgttgt cttcaatatc tccgatggtt actttatatg agttaccgtt gattttatat
    11581 ttatattctt tcatcgtttt tactttttaa aaggtgactt actttctggg aggagtttca
    11641 cgcaaagtgt aaatcttcga actccatggt gagtagctgc gttttacgcg ggtgatggtc
    11701 agcaccgttt cttctacgtc gtgcacctca tcctgcattt cgtgtaatgc catagaaata
    11761 gcagcgtata cttcgcccgg agcctgtgac agttccttag cttcatgctt gtcaatgcct
    11821 ttagatttca tagcgttgcg cttgctcaaa ttaacagcta cttttcctac aatcttaaaa
    11881 gcaataaaga gaagaatcaa tccgcagaat actacgctca tggcagaaat ggacattcca
    11941 acgccatcag catcgtgttc ttcaaacttt tccatcttgg aattgctgtc aagagtcttg
    12001 ttgttggtgc tcggagtcac gtatttatca ccgcttccac tttttacttc ccattcagct
    12061 gccccgtcgc ttacacgagc gtatgattgg ttgggaccga gcgcgcctgc gggcactacg
    12121 atctggtcga gcaacttctt gccggagtcg aacagaccta cccagttagc tgtttccgga
    12181 ttcagcttga agctggtatg gaaagtacca cggttaggtt cgccatctgc ccagaatagt
    12241 gcatgttggc gtggtttcac taaggtaagt atatcacctt tcgggataaa ataagtaact
    12301 gtatcgcccg gttggctact tactttcagc aagcaagctg ccaggtcggc gctaccgaat
    12361 gatttattga atatttcaat ccatgcgctg tgcaatccgt agtcatcttg aaaattattc
    12421 tgattgtcta tcaggatttc gttcagtacc agcttgttgt tcgacttttg ctctccacaa
    12481 gaagtcagcc caatcagcaa cagcaaagaa aggaatattc cgattttggt tttgttcata
    12541 atcgttcttg ttttaatgtg aaaagtagga ttacaacgga atattaccat gcttcttagc
    12601 cggattactc aatttcttag tctgcaactg ctgcaaagca cggataacac ggaaacgtgt
    12661 gttgcgcggt tcaatcacat cgtcaatgta gccatattta gctgcattgt aaggattggc
    12721 gaacaatttc gtgtattctg cttctttttc agcaaggaat tgagcgggat tttcctgatc
    12781 tttggcttcg cgtgcgtaca atacttctac tgctcctgct ccacccatta ctgcgatttc
    12841 agcagtcggc catgcgtagt tcatgtcacc gcgaagttgc ttacagctca ttacgatgtg
    12901 agaaccaccg taggatttac gcaatgtaat cgtaacctta ggtacagtag cttcaccgta
    12961 agcatacaat agcttagcac catgaaggat aacgccgttg tattcctgac ctgttcccgg
    13021 aaggaatccc ggtacgtcta ccaacgatac gataggaata ttgaatgcat cgcagaaacg
    13081 aacgaaacgt gcacccttac gagatgcgtt gctgtcgagc acaccagcca gatacttagg
    13141 ctgattagca acgataccta ccgattggcc gttgaagcgg gcgaaaccga tgatgatatt
    13201 ctttgcataa tctttctgga tttcaaggaa ttcaccgttg tccacaatag cgccgatcac
    13261 ttcgtacatg tcatacggtt tagtagggct gtcggggata atatcgttca aagaatcttc
    13321 cagacggtcg attgggtctg tgcaatctac ataaggagct tcttcaaggt tgttttgagg
    13381 aatatagctc aacagtttgc gaatcagttc gaaaccttct tcttctgttt gggcggtgaa
    13441 atgagtcaca cccgatttag tggagtgaac gcttgcgcca ccgaggtttt cctggctaac
    13501 gtcttcacct gtaacggtct tcaccacttt cggtccggtg aggaacatat aagaagtgcc
    13561 ttccatcatc agtgtgaagt cggtcagagc cggagaataa acagcaccac cggcacaagg
    13621 accgaagata ccggaaatct gcggaataac acctgaagca aggatgttgc gttggaagat
    13681 ttctgcataa cctgccaaag cgttgatacc ttcctggata cgtgcaccac ccgagtcgtt
    13741 gataccgata cagggagcgc ccatcttcat ggcttgatcc atgattttac aaattttcaa
    13801 tgacatcgtt tctgacagtg aaccggcaga aacagtgaag tcttgtgcga acacatatac
    13861 cagacgtcct tcgatcgtac cgcagccagt tactacaccg tctcccgggt aatgtttttt
    13921 ctccatgccg aagttcgtgc atctgtgctc aacgaacatg tccatttctt cgaagctacc
    13981 ctcgtcaagc agcatagcca gacgctcgcg tgctgtgtat ttcccttttt cgtgttgctt
    14041 cgcaattgct ttttcaccgc ctccgatacg tgctacggca cggcgttcaa taagctcttt
    14101 aattttttca agttgattac tcatgagttc ttgttagttt tagagtttat gattaatgtt
    14161 cgcagagttc tgttaacaca cccaaagttg atttcgggtg aaggaaagcg atattcaaac
    14221 cttcagcacc tttgcgggga gctttgtcga taaggcggat ttctttgcct tctgcctctg
    14281 ccagcgcatt ggctacgcca tcttctacag caaatgcgac gtggtgaacg cctgcacctt
    14341 tgttttcaat gaatttggca atagtactct ccgggcaagt aggctccaac agttcaattt
    14401 ttgtttcgcc cacttttaaa aaagcagttc ttactttctg atcttccact gtttcaatgt
    14461 tgtaacactt cagacctaat acattttcgt agtaaggaag ggcttcttcg atgcttttta
    14521 cagcaatgcc cagatgttca atgtgtgaaa tcttcataac tatacttttt ttatttggtt
    14581 ttaaatctgt gcttataagg cataaaacag cacaaagaaa gacatttctt atctaataaa
    14641 gaaatatttc tgcatttaat tattggatta ttaaacagaa aaaatggtgg gaaaggagca
    14701 taaaacattg ttttgtaatc ttgagattac atttagacat aaaatttgac taagagttta
    14761 ttcagccaac tccaattgac gcggaaccaa cggcgggtac tgctttgttt tcctccgaag
    14821 cgaagaacga aatcacgata accgtgttta cggaacggaa gtcctacatc cataaattcc
    14881 atgtggcgga atccccgttg gtgtgcgtct tccaatgctt tccaaacggc tagcacaccc
    14941 ggatattgaa gtgcgtatgt ctttctcatt cctcccgaaa accaaaggta tgcgtcgtct
    15001 cccgaataga tacagacaga accgccaatg attttctctt tgtatttcac aacgaatatt
    15061 tttgcctgtt gtcctttgat taacatattg ttcatgtggc ggaaaaaatc gttggccggg
    15121 aaatatctgc gtatgcggga ggaataaacc ttgtgcagca tccgtgagaa atcgtgtatt
    15181 tcttccacgg tatgtgcttc ctctactctg gctccattct tgagtccttt ttttatctga
    15241 cggatgcgtg acgggctgaa ccggtcttcc gtctttttca tactgtgcag cgaattgcgt
    15301 acccgcagcc agttgacagg gaaataatca ttggcacgga aaacccggta accgaacatc
    15361 gaattattga ggttccggaa ttcgatcagg acacagctac gcgatgcttc ttgtgtgaga
    15421 tgttcgagca tatcgccaaa gacttcttct gccttttctt tgttggtcga aagcgactca
    15481 tctagaaatt caccttcgct atatactacg caatgtttca ctaaagagga gggaagccac
    15541 tttttcgctt tgcggatggc agcaagcagg cgtgccacag gtctgccgtc ttctgttgct
    15601 actattaata aaggagtata ccccggagtc gcttcataaa tctgaaataa ctctttggaa
    15661 tggaaggcgt tttttccggg caattcagga atgtccttcc catgataata tgtggttagt
    15721 ttaagtggca tctaggtaca aatttacact ttttattctt tattcaacaa caaaacagag
    15781 attttgttgg aactgcctga agtaaagtac aatatatctt tgcatattta atggaaaaaa
    15841 tgtattttat aggagaaata tggtatgaaa agtgagtacg tattaaaatt aggttcgtct
    15901 taaattaaga ttataatcga atagtttttg caaaacaacg agaattaata ttaactttaa
    15961 attagaacga atgagatgta atgcatttgt tgaagcatgg aagaattatc atagacgcgc
    16021 ttccatgatt ttagggttgt ctttattggc tgcccctctg tcatacgctg tttatgcaga
    16081 agatggagtt tctaatacta tggtgcaagt tgtcacacaa acgaaaactg tgaaaggaac
    16141 tatcattgat gaaagcgggg agccgctgat tggagtttct atcgttgtga aaggaacaag
    16201 tacaggtacg attaccgatt ttaacggtaa cttctctatc gatcttccgg cgggaagaaa
    16261 agaactggtc atttcttata tcggttacaa agaacaaacg gtgactgtga caggcaacgg
    16321 accggtcaat gtgaaaatgg tttcggacac acaggcattg gatgaagtag ttgttgtggg
    16381 ttacggtacg atgaaaaaac gcgatttgac aggagctatc acttctgtaa aaagtgaaga
    16441 tgtagtgatg aatccaagtt caaatccgat gcaggcttta caaggtaagg tggcaggatt
    16501 ggatattacg cgtgaatcgg gacaggccgg ttcgggagta aagatgcagt tgcgtggtaa
    16561 ccggtcattc cagaaggatt ccggaaatcc tttatttata attgatggta tgccggggga
    16621 ttattctaca ttgaatccga atgatattga aagcattgaa gttttaaaag atgcttcttc
    16681 gacagctatt tatggttcaa gtggtgcgaa cggtgttatt ttaattacta ctaaaggtgg
    16741 taaggaaggc aaagcaattg ttaattttaa tgcatacgta ggtgtaaacg gctggtcaag
    16801 gactccggag atgcgtagtg gagaaagtta tatacaaacc ttgagagatg catctgttgg
    16861 tgctggcgat ggacgttgga gctcggttgc tgatgataaa aatctgttta ctactgatgc
    16921 tgaatggagt gcacatcaaa atggccaata tatagattgg gtggatgctt tgttgaaaac
    16981 cagtgtaaca cagaattatt ctgtttctgt ggctggtgga acggaaaaga caaaggcata
    17041 tttttctctg aacttctcta atgaggatgg gcagtttgca caagatagct ataaacttta
    17101 ttcatctaaa atccgggtag atcataagat taaaaagtgg atgaaggtgg gcattgatgc
    17161 tcaactgtct tatgtacatc aaaataaagc tgattctgat ttacagactt tgatggcgtc
    17221 aaatcctctt ggatcgttgt ataatgaaga tggaagcatc aatccgcaac ctgttgccga
    17281 tccttcatct acagtatata attatctttt aaatgaggat aaaagtttgt accgcaatca
    17341 ggctcaaaac cttaaggtct attttaatcc ttacttggaa atcactcctc ttaaagggct
    17401 gacttttatt actcgtgctg gtgctagttt gggatattca cgtagtaaca ctttcacagg
    17461 agaggggtct gttcaatggt ataaggcaaa tcaaacggca gacggcatta aggcgcaagt
    17521 taaggacaac cgttcgtata attataagtg ggaaaatata cttacttaca atttccaaat
    17581 taagaaagtg catgatataa ctcttactgc agttacatct tggaatcaca atcgtagtga
    17641 tgtcactact ttgtatcaaa aaggtgtttc tgataataaa ttcttatggc ataatattct
    17701 tgatggtaat tctgcaactt cgggaagtac ttcttatagt atgtctaagg ggatgggata
    17761 tgtcggccgt ttgaactatt catatatggg taggtattta tttgctgcat ctgtccgcca
    17821 tgacggctct tccagactgg cagaaggtaa taaatgggat actttcccgg ctttttcttt
    17881 gggatggaga atttctgatg aaaaatttat ggagagtacg actaactggt tgagtaatct
    17941 gaaaattcgc ttcggatatg gtgttacggg tagtacagcg ggtattgatc cgtattcgtc
    18001 tgctgcatca ttggatgcta ctgctgtaaa tatgatatta ggaggtgttc tgacgccgat
    18061 ttataaattc tcacagaata ttccgaacta tttgcttaca tgggaaaagt cgtataacac
    18121 gaatattggt attgacgctg cattcttaaa taatcgcatt gatgtcagta tggaatatta
    18181 taatacaaaa acaaaagatg ttatatggaa caaggcactt cctgttatta atggagcatt
    18241 ctccccggat ggcggaccta aagcgaatta tactactaat ttaaatatgt gtgagactag
    18301 caataaaggt tttgagttgg ctcttaatac acgtaatatt ataacaaaga actttacctg
    18361 gagttcaagt nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt ggagttcaag tgtaactttc
    18421 aatcataata aagagaaaat aaccaaattg tccggtggag attcagatgt gcttaataat
    18481 ggtgacaccg gttatgcatt ggcattggga gaagctatta actcttatta tcattataag
    18541 ttggatggtg tatggcaaaa aggtgaggaa actgatgcgg cggtatttgg tgctgcacct
    18601 ggtgatttga aaatcaatat acctaattta gtaaaagaat ctgatggtag attctataaa
    18661 atagatgaag aaacgggtag tgctgctgtg gatgaaaatg gtaatgttat ttattacact
    18721 tctgataata aatatactcc aagtgatgca gattatcaaa ttctgggtca caactctccg
    18781 gattggtctt taggattcca gaataatttt acctggaagg attttgattt aagtgtgttt
    18841 gtttatgcac gttacggaca gatgtttgct tatgatatgt tgacgtctta tgacccgaag
    18901 ggtatacgta acttcccgac ctatttcaat tattggactg aaaacaaccc ttcaaatgat
    18961 tttcctgccg ccaatgctaa taaaggtctc gaacaatata cgggatatta cgcattacgc
    19021 tatgtagacg gttcgtttat aaagattaag aacattacat tgggatatag tctgccgaaa
    19081 tctatcttaa aatcagccgg tatagagaag tgtcgtttct atgctaccat tacaaatccg
    19141 tttgtatttg cgaaaagcca tttgctgaaa gactatgatc cggaaatgaa tggttctctg
    19201 aagtacccat tgaccaaaca atttgtattt ggtgtaaatg ttacattcta gtttttcact
    19261 aaaaaaagta ttgaaatgaa aagtacaatc tataaaatag cagcgcttac attcgctgtg
    19321 gcttcaatgt ctgcctgctc gcttgatgag tataatccaa gccaaaaaac aggagatgaa
    19381 attcttgcaa cgttcgatgg gcttaaagga ttacagtctt attgttattc atcactttac
    19441 gggcagttat tcagtgtcta tgatttcttg tctgtggctg aaggtggtac ggactgctgg
    19501 ataactcctg ccggtaatcc ggattatgcc aagcaggtga tttattatga tggtttagct
    19561 acgaatacga atgctacaaa taaattattc ggtcaggctt attctatgat cggtaattgt
    19621 aatgcagtag taaacagggc tgaattacta acggatggca atgaaaaaga tataacgact
    19681 ttagtggctg aagcccgctg tcttcgtgcg ttttattatt ccatattggt gaatacgtat
    19741 gggaatgtaa cgttaacatt ggaagaatcg tctcaagatc ctattttgac tccgcagcgt
    19801 aactctattg aagaactata tacgcagata attgatgatt tgaaatttgc ggccaataat
    19861 cttgaagata ctccttatga taataatcgt gcgcgtgtga ctaagaaaac cgcgttagga
    19921 cttttggctc gcgtttatgc tcaaggtggt ggcgaatatg ggctgacaga agagggagta
    19981 tcttattggc aacgtgctaa agaagtggca gaggacatga ttttagcgta tggtgactgt
    20041 ctgtatgatg atgtggaaga tgtttgggct ccggcaaata atcgaaataa taaagaagct
    20101 ttatttattg ctgccggtcc ggatgctacg aatttggaga actggaatgc tggaacacaa
    20161 tgtaataaca actttactta tatgtatcca aagccaaata ctctcactat ttatcctact
    20221 ccggataatc aaaattattg gtatggacgt actaataata atacgttggc accttccaaa
    20281 tatttgctgg attgttttga tgctgattat gataagcggt gggaagtaac ctttactacg
    20341 gcttttgtac agttttctgc cgtacagtca ggaggtagtt atttatttac taataagaag
    20401 cagacattgg atgatggtac aaaaccaaaa attggaacaa aacatggcgt aaatgataat
    20461 attagttcat ttacaattct tactcaaaat ataatcgata cttatggatt ggatgcaaaa
    20521 ttccataatg agtatattta tccttatggt gatttgaatt atacatatta tgatggaact
    20581 tgggcgccca aaatgatagc caaggtttgg ccgaaaggtg aaaatagcgg tgatccttcc
    20641 aaattgcagg aagtgaagaa cccctatgtg ataccttacc ctgtagctga agatgatgat
    20701 agaatctgtt tctacttatc aaaggaaaga ctttcggatg cggagaaagc gaaacgtaga
    20761 tattatgtaa tcaatattga tgatttgttt gataacggac aatatcgtaa aacagatata
    20821 aaagttacta atgacaaaaa tatgtaccct ggtttcaaca aatacaattg gttgtcggaa
    20881 gattcatata gtagcaattt gcaacgtaag acaggtgatg tgttcattat gcgtatggct
    20941 gaagtatatc tgattgcagc tgaagctaac caacaattag gaaatggcgg aaaagctgct
    21001 gaatatttaa atgtactgaa aaagcgtgcc gctcgcaatg atgcatctta caatgctatg
    21061 aaattgagta atgctacaca gaatgatgtt atggacgaat atgctcgtga attatgtgga
    21121 gaatatcaac gttgggtatt gatgaagcgt cacaaagatt cttttaaaca acgtcttgct
    21181 gttggtaatc ctcgtgcagc tgaaaatttt gatgaaaaca agcattattt gcgtccgatt
    21241 tcttttaact tcttgagtca gattgataat gcagaagaat atggaaacaa tgggtattag
    21301 tactcttaca gattaaattt agattaaaga ggggatatgt cgtgatgata tgtccctttt
    21361 ttctatatct ttgtatcatc aaacagagct ttataattta agcggaacta tgatagaaga
    21421 aattttagct tacaacaagc aatttgttga gaacaaggga tacgaatcgt atattaccaa
    21481 taaatatccc gataagaaaa tagctattct ttcctgtatg gacacccgac tgacagcttt
    21541 gcttccagcc gcattaggaa ttaagaatgg cgatgtaaaa atgataaaga atgcaggtgg
    21601 cgttatttcc catccttttg gtagcgtgat ccggagttta ctcgtagcta tctttgaact
    21661 gggtgtggag gagataatgg tgattgctca ttctgattgt ggagcttgtc acatgcatag
    21721 tgaaacgatg cttgaaaaga tgacggcgcg ggggataaat ccggattata ttgacatgat
    21781 gcgcttctgc ggagttgatt ttcatgtctg gctgaatggc ttcgaagata cggaaaagtc
    21841 cgtgagggga acagtcgatt ttatcgtgcg tcatcctttg attccttcag atgtgacagt
    21901 ttacggattt attatcgatt ctacaactgg agaattaaca cggattgtat aataaactat
    21961 ctttttaatt cctctaaata tagtgacgct atcttgatga caaaaaaata aggcagcttt
    22021 ttatcggctg cctttatctt tctgcggtta tatactttct ttgactggtg cactcgttgg
    22081 tgacaaatag ggtgcccgta catctctatt tctgcctcac ggctagcttt acgattcgct
    22141 ttaatgtaat cgtcttgtgt aattcgcttt ttcataatga aattatttct ctgtgcaaag
    22201 atacaatata ttcttcattt agtataaact tttatttcct attacgctcg gtttgcatta
    22261 tctttgcata cattaatcaa atgaaaccgg aaataatatg gaaaatttca gtgaattaat
    22321 aaagaaccgt cgtagtatgc ggaagttcac cgatgaagaa ttgacacaag atcaggtagt
    22381 tgcgttgatg aaagcagctt tgatgtcccc ttcttccaaa cgtagtaata gttggcagtt
    22441 tgtagtggtt gatgataaag aggtattgaa agaattgtct cattgcaagg aacaggcttc
    22501 ttcgttcatt gccgatgcag ctttggcgat tgttgtaatg gccgatccgt tggccagcga
    22561 tgtttggatt gaagacgctt ccattgcttc catcatgata cagttgcagg ctgaagatct
    22621 tggcttggga agttgttggg tgcaggttcg cgaacgtttc actgccaccg gaatgccttc
    22681 cgatgaattt gtccatggaa ttttggatat tcccttgcaa cttcagattc tttctgtcat
    22741 tgctatcgga cataaaggga tggaacgtaa acctttcaat gaagaacatc ttcaatggga
    22801 gaaaattcat attaacaagt tcggaggaaa ataagtatgg gagctgctaa agcgaataat
    22861 agtaaagata cctatctggc tactgctgtt acctttatcg ttatcggagc actttatctg
    22921 attgataaac tgattcattt ctcttccatt ggactgcctt gggtgatgaa taaggacaat
    22981 atgctattgt acgcctcgat ctgtttcctt attttcaaac gcgataaatc aattggtttt
    23041 gtgttgcttg ggctttggct agtgatgaat atcggtttgg tcatgtcctt attgggttcg
    23101 ttatccggat atctgttgcc attgacactg ctcatcatcg gaatcgtttt attctggttt
    23161 gcaaaacgat aagagaataa tgaaaagaag tatagaagat acaccgatcg tgtttatcgg
    23221 tgcaggtaac ttggctacta atctggcgaa agctctttat cgtaaaggtt tccgcattgt
    23281 acaggtatat agccggacta tggaatctgc ccgtacctta gccgagaaag tagaagctga
    23341 atatacaaca gatttacagg cagtctccaa agatgcaaaa ttgtatatcg tatcgttgaa
    23401 agatgatgct ttagtagatt tgttaccgca gataacagaa ggaaagcaag cgtctttgtt
    23461 ggtgcatacg gcaggaagca ttccgatgag cgtttgggaa gggcatgcag aacgttacgg
    23521 agtattttat ccgatgcaga cattcagcaa acaacgtgaa gttaaatttc aggaagtgcc
    23581 tttctttgtt gaagcgaaaa ggccggaaga cgtggaattg ttgaaggctg ttgccgccac
    23641 actttcggaa aaggtctacg aggcttcttc cgagcaacgt aagagccttc atttggctgc
    23701 tgtttttatc tgtaacttca ccaatcacat gtatgcatta gcagctgatt tgcttgaaaa
    23761 atacaacttg cctttcgatg tcatgcttcc gctgatagat gaaacagcac gtaaagtcca
    23821 cgaattggcg ccacgtgatg cacagaccgg acccgctgtt cgttacgatg agaatgtgat
    23881 gagtaatcat cttgccatgt tggtagattc tccggcattg caggaaatat ataaactaat
    23941 gagcaaaagt atccatgagc accatcaatt atgatttatc ccgtatcaag gctttagctt
    24001 ttgatgtaga cggagtattg agttcgacaa ccgtaccttt gcatccttcc ggagaaccga
    24061 tgcgcacggt gaatatcaaa gatgggtacg ccatccagtt ggctgtgaaa aaaggacttc
    24121 acatagctat catcaccggt ggccggacag aagcggtacg tatccgtttt gagggactgg
    24181 gagtgaagga tttatacatg ggttctgctg tgaagataca tgattatcgt gcttttcgtg
    24241 ataagtacgg attgaccgat gatgaaattc tatatatggg tgatgacgtg ccggatattg
    24301 aagtgatgtg tgagtgcgga ctgccatgct gcccgaaaga tgccgtgccg gaagtgaaat
    24361 ccgttgcaaa gtatatttct tatgcagacg gtggtcgtgg atgcggacgt gatgtagtgg
    24421 agcaggtgct gaaggctcac ggtctatgga tggtggaaga cgccttcggt tggtaactta
    24481 atcataaata atcgttgttt aataacgaat aaaaccatgc ttgataactt aaataaatat
    24541 cagattatat tagcttc
//
