LOCUS       gnlProkkaFBEMLICP_56   12142 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FBEMLICP_56.
ACCESSION   gnlProkkaFBEMLICP_56
VERSION     gnlProkkaFBEMLICP_56
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:23:28
            Original ID  :: gnl|Prokka|FBEMLICP_56
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 99153
            Orig. end    :: 111295
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12142
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7142]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7142
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..12142
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12142
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(1429..2871)
                     /locus_tag="ctg38_98"
                     /transl_table=11
                     /translation="MEKHQMKQLYQDIDVPKAELKNVIHSAAVRAGKEGAVRRRWGRKV
                     INGLAVAAALFILYLSSGLFMPSVNTAMGNIPVAGQIYSLFQDKAGSALFKSNLVTKLN
                     EKAESRGITVTVKSVYYDSGQLVYNFTVDNLKSDEESISFQVDYKDPWNMLAEDYDNSD
                     MKKMKDGRYAGQLRLFTDGSKLKDGDKLPLVITQIKDIPGNWRFTLPIKKQKSVSLEGT
                     KAVNVNHGLYRFFDIRAENGTMGSALLYSIDFQDAAKNDAISIDEATDDAGNHYEMTMS
                     NIELGGRKNLPGGGKRIRGQTQFSKPIDPKAKTLFITGNLKSESEPGEIVPLKTKLPVS
                     YKTKHHHVGITIKKIKQQGRTVIVDYQFTGINYSKADEDQLINVGESIGLGNTKKMKTW
                     PSLNEYEKGYYLKGNKAKVTNLKTGEMESVFELDDSTDKDYSLRDFSFDSYALYVNQTV
                     MNLLADDKGITFAVPIRPADGK"
     CDS             complement(2853..3386)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 106.3;
                     E-value: 2.4e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg38_99"
                     /transl_table=11
                     /translation="MKEERLIKKAKKGDAAAFEKLITAHQDTLYKTAYLYLHHKEDTLD
                     AVQETAYKAFLHIAQLKEPKYFKTWLIRILLHTIFAMRKKHGDVIPFEPQHDTRAENKN
                     IEEYIDLRNALETLDEHIQLTIQLYYFQDFSIAMIAEQTGMAEGTVKTHLHRARKALKQ
                     ELEKEDKHIWKSIK"
     CDS             complement(3704..4936)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 254.7; E-value: 1.8e-77)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_100"
                     /transl_table=11
                     /translation="MKGIRLRIHPVGWNIILGTLFSRMSVSMSIPFLSIYLTQVKGVSP
                     ALTGIIVSVSSLAGIVMSFYGGYLSDLFGRKIVMITSVFCWALVFVSFMFADSVLAFFV
                     INALNGLCQSIFEPASRALLSDISKEENRLKMFNLRYTAINIGVVFGPLLGLRLGAAKT
                     ALPFLFAGFTYFLYGLSLVFSFRKFKLDENNRKENKTTIATAFNVTRKDKVFLITLLGV
                     ILSISGYAHFSTTLPQYFAAKIEDGVTIFSWLLALNAIVVLIVQYPIVNIMKKFPPIHS
                     IILGNALISFSLLFFSLSSNPFIWGSIVVFFTIGEVLIFSMVDMLVDEIAKPGFKGTYF
                     GAAGFNRLGNVIGPWLGGILLSFFGVNGSFYMFLIIFITTASGIPVLFLAKKHLDKCGH
                     SKVDVTESHRS"
     CDS             complement(5001..6200)
                     /NRPS_PKS="Domain: Aminotran_1_2 (32-388). E-value:
                     1.9e-69. Score: 226.3. Matches aSDomain:
                     nrpspksdomains_ctg38_101_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 287.8; E-value:
                     2.2e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_101"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.9e-69, bitscore:
                     226.2, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4e-11, bitscore:
                     36.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKRLSDRVMNIKPSATMSLNAKTKIMVKEGKDIINMSVGEPDLH
                     PPLTASYAGIQAIVKGKTGYTPAAGLIELRESIVRYLLNERGLEYKPNQIIASAGGKQP
                     LYNVFQAICDQDDEVILPSPYWVSYPEQIKLSGAVPVIVSCDETTNFKITPEKLAEVIT
                     PKTKAVVITSPNNPTGSVYSENELKALGNVLKDYSEIFIISDEIYDQFVYEGKHISLPL
                     IFPELLNRTIITNGFSKVFAMTGWRLGYIAAPSDIAEAIASFQSHATGSPSTISQYAGI
                     SALNGFDKSMVEEYKKRRDILVDGLNQIEGIQCAKPNGAFYAFPNVSQFFGTMFEDQQI
                     IDAETFCHLLLEKQHVSAVPGTAFGEPNNIRLNFAIPKDLITEALKRINNFTTQLAVKV
                     "
     aSDomain        complement(5037..6104)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_101_Aminotran_1_2.1"
                     /evalue="1.90E-69"
                     /label="ctg38_101_Aminotran_1_2.1"
                     /locus_tag="ctg38_101"
                     /protein_end="388"
                     /protein_start="32"
                     /score="226.3"
                     /tool="antismash"
                     /translation="DIINMSVGEPDLHPPLTASYAGIQAIVKGKTGYTPAAGLIELRES
                     IVRYLLNERGLEYKPNQIIASAGGKQPLYNVFQAICDQDDEVILPSPYWVSYPEQIKLS
                     GAVPVIVSCDETTNFKITPEKLAEVITPKTKAVVITSPNNPTGSVYSENELKALGNVLK
                     DYSEIFIISDEIYDQFVYEGKHISLPLIFPELLNRTIITNGFSKVFAMTGWRLGYIAAP
                     SDIAEAIASFQSHATGSPSTISQYAGISALNGFDKSMVEEYKKRRDILVDGLNQIEGIQ
                     CAKPNGAFYAFPNVSQFFGTMFEDQQIIDAETFCHLLLEKQHVSAVPGTAFGEPNNIRL
                     NFAIPKDLITEALKRI"
     CDS             complement(6258..7142)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 264.8;
                     E-value: 1.5e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_102"
                     /sec_met_domain="phosphonates (E-value: 2e-109, bitscore:
                     358.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates-like (E-value: 1.2e-127,
                     bitscore: 417.8, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 8.2e-69, bitscore:
                     225.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNRKSSIFRDALNSKGLVKVAGAHDGLSAKLAEKNGFNAVWASG
                     LGISAVQTVPDASILTMTEFLEAAVIMNESCNLPVIADCDSGYGNIHNVTRMIKKYEAA
                     GIAGVCIEDKVYPKLNSFDDRQQILVSTEEFCAKIRAAKMAQQNDDFVLIARVEALIAK
                     LGQEEAYTRAKAYVHAGADAILIHSKEQSPDEIIEFVNNWDVDAPLVVVPTKYPTLSME
                     QLEKLGVKVSIYANQALRASVKAINDTFESIINNKSSLQIENDIVSVNEIFDIQDVPGM
                     KQLERLIHRQPAN"
     CDS             complement(7157..8368)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_103"
                     /sec_met_domain="ATP-grasp_3 (E-value: 9.3e-17, bitscore:
                     54.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 5.6e-07, bitscore: 22.6,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.5e-11,
                     bitscore: 35.9, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 3e-10, bitscore: 33.2,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRLFLIGIPETHIEKAVTRAKQLGFDVLLGDTEASLKKYEHL
                     IKEADQKIALDYTNHENLFSVAKEIHDKEPLDAIFTFKEAGLFNVSKLQQAFHLKGNPP
                     SVVQACLDKYTTRRLLKKAGLNSPDFGLCRSVEDVYDFWNTSQHPIILKPRSQQGSIGV
                     IKVEKKEDIEACFKECSKHDEEKSVLAEEFIEGQEISIEAVVCQGKVDIFGVTEKLLYP
                     GTFVESGHISPYKHKEKHQDLYKNLVKEVVHAMGIVFGPLHIEGYHTNKGFVVGEVHTR
                     YGGDNIVTITEIAMKCDMHTPIFAELAGIPYQPERKHAQSEVCAVRFLETNQGVVRAIK
                     GISDLKMMGNVVDFHVNCSVGDRIRPIKNSYDRAGWMIVKGKNEREVNHALHDAIDKIK
                     IIIR"
     CDS             complement(8331..9593)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 72.2; E-value: 7.2e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_104"
                     /sec_met_domain="ATP-grasp_3 (E-value: 5.1e-14, bitscore:
                     45.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4.3e-09, bitscore:
                     29.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 6e-08, bitscore:
                     25.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHILFFNATYIKKISTLETAKNLGLTVSVVGPELPEWSRPFVD
                     HYISANTYQIDETIAVLKETAKENPFDGVITFWDRDVVPVAVTARELNLKGSPVEAAER
                     ARNKWKMRQFLNRAQVPHPKYCKFTNWTELYHASIDMEYPLIVKPVGASASKGVFRISK
                     PEDLNRAYQQLLNAAVPENDKMFSFYQNEYIVEEFMNGQEVSIEGVISDGVIHFAGVTE
                     KWTDQYFEEYQHAFPARLPEAVERELFHITSEGIKALELNNCGFHAEVMITEKGCKIIE
                     INGRLGGDFITTHLVPLAKGINITRANLLAVLGETISFEASKRRAACVRFLIADRAGVI
                     EKWEGVESIKEMPGVVEFVLEKQPGDHVGLPPEKFHDSRIAYVITEAEDTEKAIEYAEN
                     ALSEVRCFINGEEKTVPDRDS"
     CDS             complement(9974..11206)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 128.5; E-value: 7.5e-39)"
                     /gene_kind="other"
                     /locus_tag="ctg38_105"
                     /transl_table=11
                     /translation="MPKTNYQDIYQDKNGQYYYEVSLGTDKITGKRIKRKGRKSQSGKK
                     FESAKEAYAEAIRVKNDFLQTQGYSDYGMTFEQFMNNVYIPHYKTEVTEDTFESRNPPL
                     KILIGRFGKKPLRKITLHDIQFFRTWLLDKNAAGYSQSYASMVFGMLKKILEFALTLNY
                     LDKNVAQQVKPIPKVKTDVAYWTKNEFEKVISKIYTEDFYEHMCFVKLWVYYMTGIRVN
                     EGTALWWNDVDFEKKQLRVHHMLVTKSRKNYNRKNHTKTVDGKRVLALDGDTLEVLRVW
                     KERQAQHGNMDFIFSYGGLPMIKSTIARIIARYAKLAGVPVIQAKGLRHSHVSFLINEL
                     NASVLVVSKRLGHSSPEITLKHYAHLWRGIDDAVAESMAGVIKIETATSKQFTFVGNQA
                     VKQLSPKMSPR"
     CDS             complement(11209..11415)
                     /locus_tag="ctg38_106"
                     /transl_table=11
                     /translation="MSKTMVNSEDLKRAGFSPYTASNIIRQAKHYMVQQGYEFYEGRRI
                     SVVPIQAVKSVIGDVELSEKTEE"
     CDS             complement(11408..12022)
                     /locus_tag="ctg38_107"
                     /transl_table=11
                     /translation="MVKKKEQRSNKWAFILYQESAPENYLEIFEEMHIPFVLSPWHDKD
                     MNKETGEIKKAHKHGALYFDSLKSYSQVSSLISDKLNAPKHVEVVMSPKGMYEYFTHAD
                     NPGKTPYQTEDIEWGCGFELGKFLVEHNTGEFLNSIIDVIAEHDFKEFEELVMYARKND
                     YLLLELIVDKTYFFSRLLDSRRYSSERPTRKINEEMGEGDE"
ORIGIN
        1 ccggagccgt cacattcgtg gtgacaactg acagaagcgg cgagaaaaac atcgccagca
       61 aaaagagaat gcccgtcaca acagccgcga agccggagcg cgcccccgcc gcaacgcctg
      121 agctggattc aacataagaa gtcgttgtag acgtaccgag tacggctccg ataacgattg
      181 atgtcgaatc cgccagaagc gctcttcccg cacgcggaag tttgttttcc ttcatcagcc
      241 cggcctgtgt cgctacagcc accagcgttc cggccgtatc gaaaaacccg acgaacaaga
      301 aagttaaaat gacaatcagc atttgtacgg agaagatatc cggaagatgc atccacgcct
      361 gtccgaaagt cggcgcaaga ctcggcacgc tgccgacaat gtgcgtcgga accggaatca
      421 gcccgcagac catgccggca accgccgtca gaagcattcc gataaatacg ccgccgttta
      481 cgcgaagcac catcagaatg acagtcacaa taacaccgaa aaccgtcaga agcacagggc
      541 cgctgtgaat attgccgata gacaccagag tcgatgagtt cgcttcaata atgcccgaac
      601 cctgcaaacc gacaaatgtg ataaacaaac cgatacccgc gccgaccgcc aatttcagct
      661 caggcggaat cgcattaatg attttttccc gcagtcccgt cagcgaaagc gccacgaaga
      721 taattccgga aatcaagacg ccggaaagcg cagcctgcca tgaaatcccc atgccgagga
      781 cgacagagaa agcaaaaaac gcatttaatc ccatacccgg cgcaatcgcg atcggatact
      841 ttgcaatgag ccccattaaa atacagccgg ccgcagacgc caaggctgta gcggtgaaca
      901 ccgcgccctg atcaattttt aatgcttccg gaaatccctt cacaccgttt aaagacaatg
      961 tcagcggatt gacgaacaga atgtacgcca ttgacaaaaa ggtcgttaaa ccgccgatga
     1021 tttcattgcg atagcttgtc cccagctcat caaactgaaa aaattgcttc aagccaattg
     1081 cctccttcat tctctcccat ttattctgcc cgttatccgc caaataaaaa acgccccaaa
     1141 tacatttggg acgcttgact acatacgttc agtctgaata aataagaatg gattatttat
     1201 atcaaacgat tgagattgat ccgtagtcaa gccatttacg gtagcttggt agaaacttgc
     1261 gggccatatc cccgccatta tacgatatct gcatatttga tttctgagtc tattgtatca
     1321 attcaatttt gaaaactcaa taaaaaaaac gaacaatccc ggtaaaaaaa tttggtttat
     1381 tcgttaattg accaaaaatg gaagacggca aaagccgcct tccagacatc attttccgtc
     1441 cgcaggccga atcggcaccg cgaatgtgat ccccttatca tccgccagca agttcataac
     1501 cgtttgattg acgtacaaag cgtatgaatc gaatgagaaa tcgcgcaacg aatagtcttt
     1561 atcggttgaa tcatctaatt caaaaacgga ttccatttca cccgttttaa ggttcgtgac
     1621 tttcgcctta ttccctttca gataatagcc tttttcatac tcattaagcg atggccaggt
     1681 tttcattttt ttcgtattgc cgagaccgat tgactcaccg acattgatca gctgatcttc
     1741 atccgccttg ctgtaattga ttccggtgaa ttgataatcg acgattaccg ttctgccttg
     1801 ctgtttgatc tttttgatgg taatgccgac atgatgatgt ttcgttttat aactgacggg
     1861 cagttttgtt ttcagaggca cgatttctcc cggctctgat tctgatttta aattacccgt
     1921 tatgaaaagt gttttcgctt tcgggtctat cggtttgctg aattgagttt ggccgcgtat
     1981 tcttttcccg cctccgggaa gattctttct gccgccaagt tcaatattcg acatcgtcat
     2041 ttcataatgg tttccggcat catccgttgc ctcgtcaatc gagatggcat catttttagc
     2101 tgcatcttga aagtcgatag aatacaggag agccgatccc atcgttccgt tttccgcccg
     2161 gatatcgaaa aagcggtata atccgtgatt tacattcaca gctttcgttc cttcaagaga
     2221 aacggacttt tgttttttga tcggaagtgt aaaccgccag tttccgggga tatccttaat
     2281 ttgtgtaatg acaagcggaa gcttatcacc gtctttcagc tttgagccgt ccgtgaacag
     2341 gcgaagctgt cccgcgtacc gtccgtcttt catttttttc atatcactgt tgtcataatc
     2401 ctctgctaac atattccatg gatctttata atcaacttga aaagagatgc tctcctcatc
     2461 tgatttcaaa ttgtcaacgg taaaattgta aacgagctgt ccgctgtcgt aatacacact
     2521 tttcactgtc accgtgattc cgcgtgattc cgctttctca ttcagttttg tcaccaaatt
     2581 gcttttaaac agcgcagaac ctgccttatc ctgaaacaga ctgtaaattt gtccggcaac
     2641 aggaatgttt cccatagctg tattaacgga gggcatgaat aagcctgagg acaaatacag
     2701 aataaacaaa gcagcagcaa ccgcgagtcc gtttatcact tttcgtcccc atctccgtct
     2761 gacggcgcct tcttttccgg cacggacagc ggcgctgtgt atcacatttt tcaactcagc
     2821 tttcggcacg tcaatgtcct gatacaattg cttcatttga tgcttttcca tatatgttta
     2881 tcctcctttt ccagctcctg cttcaatgct tttctcgccc tgtggagatg cgtttttaca
     2941 gtgccttccg ccataccggt ctgttcagcg atcatagcaa tcgagaaatc ttgaaaataa
     3001 taaagctgaa tggtcagctg tatatgttcg tcaagcgttt ccagggcatt ccgaagatct
     3061 atgtattctt caatgttctt attctccgcg cgcgtatcat gttgcggctc aaacgggatg
     3121 acgtctccgt gctttttcct catcgcaaaa atcgtatgaa gcaaaatccg gatcagccac
     3181 gttttaaaat atttcggctc cttcagctgc gcgatatgaa gaaaagcctt gtaagccgtt
     3241 tcctgaacag cgtccagcgt atcttccttg tgatgcaaat agagataagc tgttttatat
     3301 aaagtatcct ggtgtgctgt gatcagtttt tcaaaggctg cggcatcacc ttttttcgcc
     3361 tttttgatca gtcgttcttc cttcacctta tccacctcct atgctgttag atatgaatca
     3421 aggcaaaacg gtttcaaaaa gatgaaaaaa aacgcctcaa agtctaattt cggataacaa
     3481 cgatccgttt caaacttgaa ggtgtttttt aatttgtctc atcttatggt gtcagtccct
     3541 tagattaata ccttctttgt tcgccgttca ctctgtattc ctctccccaa aaatataaac
     3601 actcttgttt cccattctga tgggtcgttg ctgaaaagaa aaaagccttt aaacctttga
     3661 ggttcaaaga ctttgccatt aattcttcat tgtgttaaaa catttaactc ctatgagatt
     3721 ctgttacatc aacttttgaa tgtccgcact tatcaagatg tttttttgcc aaaaataaaa
     3781 ccggaattcc cgaggctgtc gttataaaaa tgatcaaaaa catatagaag gacccgttta
     3841 caccaaaaaa ggaaagaaga atccctccca gccaaggacc gattacattt cctaaacggt
     3901 taaagcctgc tgctccaaag tatgtccctt tgaagcctgg ttttgcaatt tcatccacca
     3961 gcatatcaac catcgaaaaa atcaaaactt cccctattgt gaaaaacacg acgatagagc
     4021 cccatatgaa tgggttggac gatagcgaaa aaaataataa actgaaacta attaaagcat
     4081 ttcccagaat gattgaatga atcggcggga actttttcat gatattcaca atagggtatt
     4141 gaacgattaa gacgacaatt gcattcaaag ctaaaagcca tgaaaatatg gtcaccccgt
     4201 cctctatttt ggcggcaaaa tattggggca atgttgtaga aaagtgcgca tatccggata
     4261 ttgataatat cactccaagt aatgtgataa gaaaaacctt gtctttcctt gtcacattaa
     4321 aagccgtagc aatagtcgtt ttattttctt ttcgattgtt ctcgtctaat ttaaattttc
     4381 ggaatgaaaa tacgagagat agaccataaa gaaaatatgt aaaacctgcg aacagaaatg
     4441 ggagagccgt cttggcagct cccaatctaa gacctaaaag aggaccgaaa actacgccga
     4501 tattgatcgc agtataccgc aaattaaaca tcttcaaacg attttcttct ttgcttatat
     4561 cggataataa tgctcttgac gccggttcaa agatagattg acacagcccg ttaagcgcat
     4621 tgatgacaaa aaatgcgagt acactatctg caaacataaa acttacaaaa acaagcgccc
     4681 aacaaaatac agacgttatc atcacaattt tcctgccaaa aagatcagac aaataccctc
     4741 cgtaaaagct cattacaatc ccagccagcg aacttactga cacaatgatg ccggtcaaag
     4801 caggagaaac accttttact tgtgttaggt aaatagaaag gaagggaatg ctcatcgaga
     4861 ctgacattct gctaaacaag gtgcctaaaa tgatattcca gcccacaggg tgaattctta
     4921 atcgtatgcc tttcaaaaaa ccacctgcct aaacattaga tgcagatata aagaggctcg
     4981 tttaagcttt cagcgctctg ttatacctta actgccagct gagttgtaaa attattaatt
     5041 cttttcaaag cctctgtgat aagatccttt gggatggcaa aattcaaacg aatgttgttc
     5101 ggctctccga atgctgtgcc gggaacagct gacacgtgct gtttttccaa cagaagatga
     5161 caaaatgtct ccgcatcaat tatttgttga tcttcaaaca ttgttccgaa aaattgtgaa
     5221 acattcggaa acgcataaaa ggctccattt ggtttggcgc attgaatgcc ctcaatttga
     5281 tttaaaccat cgactaatat atcgcgtctt tttttgtatt cttcgaccat cgacttgtca
     5341 aaaccgttta aagcagaaat accggcatat tgagaaatag ttgacgggct gcctgtagca
     5401 tggctttgaa agctggcaat ggcttcggct atatccgatg gggctgcgat atagccgagc
     5461 ctccatccag tcattgcaaa gactttggaa aatccattcg ttatgatggt ccgattcagc
     5521 aattcgggaa aaatgagcgg cagactgata tgcttgccct catacacaaa ctgatcataa
     5581 atttcgtcgg aaatgataaa aatttcagaa taatctttca acacatttcc taaagctttc
     5641 agttcatttt ctgaataaac ggaccctgtc ggattattgg gagatgtgat aacaacagct
     5701 tttgtcttag gggtaattac ttctgcaagc ttctcgggtg tgattttaaa atttgtagtt
     5761 tcatcacagc ttacaataac aggaaccgcc cccgacagtt tgatttgttc cggataagat
     5821 acccagtaag gtgaagggag gataacttcg tcgtcttgat cacaaattgc ttgaaaaaca
     5881 ttatatagcg gctgttttcc cccggcagat gcaattattt ggtttggttt atattctaaa
     5941 cctcgttcgt taagcagata tcgcacaatg gattctctta attcaatcag ccctgctgcc
     6001 ggcgtatacc cggttttccc cttcactatt gcctgaattc ctgcatatga ggctgttaat
     6061 ggcggatgaa gatccggttc tccgacactc atatttataa tgtcttttcc ttcttttacc
     6121 attatcttcg ttttggcatt taatgacata gtggccgaag gttttatatt catgactcta
     6181 tcggataatc ttttattcaa ttcaaacgcc tccaatgtct ttatgggcca ttcttaaaat
     6241 agcacgatac aaaaacctca gttagccggc tgtctatgga tcaaacgctc cagttgcttc
     6301 atccccggaa cgtcttgaat gtcaaatatc tcattaacgc tcacgatgtc attttcaatc
     6361 tgcaaagacg atttattatt tataatgctt tcgaatgtat catttatagc cttaacagaa
     6421 gcgcgcaacg cctgattcgc atagatggaa accttcactc ccaatttctc aagctgttcc
     6481 attgagagcg tcggatattt agtcggaacc acaaccaacg gcgcatccac gtcccaattg
     6541 ttaacaaact caataatttc atcaggcgat tgttcttttg aatgaattaa aattgcatct
     6601 gctccagcat gaacataagc ttttgctctt gtataggctt cttcttgacc caatttagca
     6661 attaaagctt cgacacgggc aatcaataca aaatcgtcat tttgctgagc catctttgcg
     6721 gctctaattt ttgcgcaaaa ttcttcagta ctgacaagga tctgttgtct gtcgtcaaat
     6781 gagtttaatt ttggatatac tttatcttca atacaaactc cggcaatacc agcagcttcg
     6841 tattttttga tcatgcgggt gacattgtga atgttcccgt agccggaatc acagtcagcg
     6901 atgaccggca aattgcatga ttcattcata atgacggcgg cttcaagaaa ttcagtcatc
     6961 gttaatatac tggcatcagg tacagtttgc acagccgaga ttcccaaacc gcttgcccat
     7021 acggcattaa atccgttttt ctctgctaat ttggcgctta aaccgtcatg agctcccgca
     7081 actttcacca aacctttact gtttaaagca tctctaaaaa ttgatgattt tctgtttttc
     7141 accatcattc tccccttcac ctaatgatta tttttatttt gtcaatcgca tcatgtaatg
     7201 cgtgattgac ttctcgctca tttttcccct ttacaatcat ccatcctgct ctatcgtagc
     7261 tgtttttgat cggtctgatt ctatcaccga cactgcaatt tacatgaaaa tctactacat
     7321 tccccatcat tttgagatcg ctgatccctt tgattgcgcg tacaacccct tggttcgttt
     7381 ctaaaaaacg aacggcgcat acttcgcttt gagcatgttt cctttccggt tgatatggga
     7441 tgcccgccag ttccgcaaaa ataggtgtat gcatatcaca tttcatggcg atttctgtaa
     7501 tggtcactat gttgtctccg ccatagcggg tgtgtacctc gccaaccaca aatcctttat
     7561 ttgtgtgata cccttcaata tgcaaggggc caaatacgat ccccatggca tgaacaactt
     7621 ccttgaccag attcttatac aaatcctgat gtttttcttt atgtttatac ggcgatatat
     7681 gcccagattc tacaaaagtc ccggggtata gcaacttttc ggtcacacca aatatgtcga
     7741 ccttgccttg gcagacaacg gcttctattg aaatttcctg cccttctata aattcttcgg
     7801 ctaatactga cttctcctcg tcatgttttg aacactcttt aaagcacgcc tcaatgtcct
     7861 cttttttctc aacttttatg acgcctatac tgccttgctg agatctcggc tttaaaatga
     7921 taggatgttg agatgtattc caaaaatcgt atacgtcttc cacgctcctg cacaatccaa
     7981 aatcgggaga gtttagtcct gcctttttta aaagccggcg cgttgtatat ttatcaaggc
     8041 atgcttgcac cacagacgga ggatttcctt ttaaatgaaa tgcctgctga agtttggata
     8101 cattgaataa gccggcttct ttgaaagtaa atatggcatc taaaggctct ttgtcatgga
     8161 tttctttagc gactgagaat agattctcat gattggtata atctaatgcg attttttggt
     8221 cagcttcctt tattaaatgc tcatattttt ttaatgaagc ttctgtatct cctaataaga
     8281 cgtcaaaacc aagttgtttt gccctcgtaa cggccttctc aatatgcgtt tcaggaatcc
     8341 cgatcaggaa cagtcttttc ctctccattg atgaaacacc tcacttcaga taaagcattt
     8401 tcagcatatt cgatcgcttt ttctgtatct tcagcttctg tgatgacata agcaatccgg
     8461 gaatcatgaa acttttcagg cggcaggcca acatgatcgc ccggctgctt ttctaaaaca
     8521 aattcaacga ccccgggcat ttctttgatc gattcgacac cttcccactt ttctatcaca
     8581 ccagcacggt ctgcaattaa aaacctgacg caggcagctc ttcttttcga agcttcaaag
     8641 cttattgttt ctcctaatac agccaatagg tttgcgcgcg ttatatttat acctttggct
     8701 agaggaacca aatgggtagt aataaaatcg ccgcccagac gaccgttgat ctcgataatc
     8761 ttgcaccctt tctctgtgat catgacctcg gcatgaaaac cacaattgtt cagctccaaa
     8821 gcttttatcc cttcactggt gatgtggaat aattcacgtt ccacagcctc cggcagcctg
     8881 gcgggaaatg catgctggta ttcttcgaaa tactgatccg tccatttttc agtaacacct
     8941 gcaaagtgaa tgactccgtc ggaaatcact ccctcaatgc tgacttcttg tccgttcata
     9001 aactcttcaa caatatactc gttttgataa aaagaaaaca ttttatcgtt ttccggcacc
     9061 gcagcgttta acagctgctg atatgcgcgg tttaaatctt caggctttga tattcggaat
     9121 acgcctttac tggcagaagc acccacaggt ttaacgatca atgggtattc catatcaatg
     9181 cttgcatgat ataattcggt ccaatttgta aatttgcaat attttggatg aggaacttgt
     9241 gcgcggttca aaaattgacg catcttccat ttgtttcgag cccgttctgc cgcttccacc
     9301 ggactgccct ttaagttaag ttctcgggca gttaccgcca ccggaaccac atctctatcc
     9361 cagaatgtaa tgactccatc aaaaggattt tctttggcag tttccttcag aacagctata
     9421 gtctcatcaa tctgataagt atttgcggaa atgtaatggt caacgaatgg ccgcgaccat
     9481 tcaggcagtt cagggccgac aacagaaacc gtcaagccca aatttttagc agtctccaaa
     9541 gtagaaattt ttttaatata agtagcatta aaaaataaaa tatgtttttc catccttccg
     9601 agcctctttc aacatttttt tctgcaaatt agaaaccttc tgcgtttcta aagaactgaa
     9661 tgcagaagat aaaaaacccc ttggaaaact caaaccatca tatgttttat ttgtatatat
     9721 tcataataac atacattatt tgttattaaa tgaatatttt aagaattcag tttcattaga
     9781 aaaattgaaa ttatagggag aatatcttct ccggtgttaa tgataaaagg ccctttattc
     9841 ctagaaccat gtaaattaaa aaagcctcaa atctttataa ataaaagatt tgaggctttt
     9901 ctcattattc ccactcaata gtgcgggtaa gacttatgaa gcctgttgtt gccacttttc
     9961 taaggtgtct ccattacctt ggagacattt ttggagacaa ttgtttcacc gcttggttac
    10021 cgacaaatgt aaattgctta ctcgttgcag tttcaatttt gataacacct gccattgatt
    10081 cggcgacagc atcatcaatc ccacgccaca aatgtgcata gtgttttaga gtaatttctg
    10141 gcgaactatg cccgagacgt tttgagacaa ctaagaccga agcatttaat tcattgatga
    10201 gaaagcttac atgagaatgg cgtagtcctt ttgcctgtat tactggaaca cctgcaagct
    10261 tcgcataacg agcaataatt cgtgcaatcg ttgatttaat catgggtaag ccaccatagg
    10321 agaaaatgaa atccatattt ccgtgttgtg cttgtcgttc tttccataca cgcaacactt
    10381 caagcgtatc cccatctaaa gcgagcaccc gttttccatc gactgttttt gtgtggttct
    10441 tccgattgta attcttgcga ctcttagtaa ctagcatatg atgaacacga agctgttttt
    10501 tttcaaaatc aacatcgttc caccagagag ctgttccttc attcacacga atgcctgtca
    10561 tatagtaaac ccacaacttt acgaagcaca tatgctcata aaagtcttcg gtgtaaatct
    10621 ttgagattac tttctcaaat tcgtttttcg tccagtaagc aacatctgtt ttcactttag
    10681 gaattggttt cacttgttga gcaacattct tatcaaggta attgagagtt aaggcaaatt
    10741 cgagaatttt tttcaacatt ccaaagacca ttgaagcgta tgactgtgaa tatcctgccg
    10801 catttttatc taaaagccac gttctgaaaa attgaatatc gtgcaaagta atcttccgta
    10861 atggtttttt tccaaaacgt cctatcagaa ttttcaaagg cggattccgt gactcgaacg
    10921 tatcttccgt cacctccgtc ttataatgtg gaatgtagac attgttcatg aattgttcaa
    10981 aggtcatgcc ataatctgaa taaccttgag tttgcaaaaa gtcatttttt acacggatag
    11041 cttccgcata agcttctttt gctgactcaa atttctttcc agattgcgac ttgcgacctt
    11101 tacgcttgat acgttttcca gtgattttgt ccgtacctaa gcttacctcg taatagtatt
    11161 gcccattttt atcttgatag atatcttgat agttagtttt tggcaaagtt attcctccgt
    11221 tttttcggac aactcaacat caccgataac ggattttact gcctgtatgg ggacaacgga
    11281 aatccgtcgt ccctcgtaaa actcataccc ttgttgtacc atatagtgtt ttgcttgtct
    11341 aatgatattg gaagccgtgt aaggtgagaa gccagcacgc tttaagtctt ctgagttcac
    11401 cattgtttta ctcatcgccc tcccccattt cttcattaat ttttctagtg ggtctttctg
    11461 aactgtaacg ccttgagtct agtaaccttg agaagaaata cgttttatct acgatcaact
    11521 caagcaacaa ataatcattt tttcttgcgt acataacaag ttcttcaaat tctttaaaat
    11581 catgttccgc tatcacatca ataatgctgt ttaaaaattc accagtatta tgctcaacaa
    11641 gaaactttcc aagttcaaat ccacaccccc actcaatatc ttctgtttgg tagggtgtct
    11701 tacctggatt atcagcgtga gtgaaatact catacattcc ctttggagac atcacaacct
    11761 caacatgctt tggagcgttc aacttatcac taatcaggct cgaaacctgc gaatagcttt
    11821 tcaaagaatc aaagtatagc gcaccatgtt tgtgtgcctt tttaatttcc ccggtctctt
    11881 tattcatgtc cttatcgtgc caaggactca acacaaaagg tatatgcatt tcttcaaaaa
    11941 tttccaaata gttttctggg gcactctctt gatagaggat gaacgcccat ttattgcttc
    12001 tctgctcttt ttttttcacc atatttcata cccctcgatt attgattatt gattccacgg
    12061 gggtcgtagt aaccccgtgg aatatttttc cgccagtttt aaaaaatcga agcttatttg
    12121 cttctgccaa ggcaggcaaa ag
//
