LOCUS       gnlProkkaKCPIDHJJ_112  12204 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCPIDHJJ_112.
ACCESSION   gnlProkkaKCPIDHJJ_112
VERSION     gnlProkkaKCPIDHJJ_112
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-16 23:48:03
            Original ID  :: gnl|Prokka|KCPIDHJJ_112
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12204
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12204
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3674:6812]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3675..6812
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..12204
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12204
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(18..122)
                     /gene="allorf_00018_00122"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_00018_00122"
                     /protein_id="allorf_00018_00122"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIILVMMPTATFRSSSICVTTKDTLSFFPTVRLS"
     CDS_motif       complement(93..122)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MIILVMMPTA"
                     /locus_tag="allorf_00018_00122_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18..92)
                     /prepeptide="core"
                     /locus_tag="allorf_00018_00122_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.80"
                     /molecular_weight="2513.9"
                     /monoisotopic_mass="2512.4"
                     /core_sequence="TFRSSSICVTTKDTLSFFPTVRLS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIILVMMPTA"
                     /leader_location="[92:122](-)"
                     /alternative_weights="2531.9"
                     /alternative_weights="2549.9"
                     /alternative_weights="2567.9"
                     /alternative_weights="2585.9"
                     /alternative_weights="2604.0"
                     /alternative_weights="2622.0"
                     /alternative_weights="2640.0"
                     /alternative_weights="2658.0"
                     /alternative_weights="2676.0"
     CDS             complement(816..1481)
                     /locus_tag="ctg112_1"
                     /transl_table=11
                     /translation="MKKKEIVIGVSVLISASLPISVYAASNESMSSRGFIIDETNEFED
                     IVKQILDVKSKHPEWSEQQISDFMDQIHAIKKDGVIDIWNALTSSEKKLVIRYPFDALK
                     VNKAKEIATKQTERKFGKNGLGDRSDAFRHGIWNAEMTVLIGSEKAELFATAHEDKDTT
                     GNESDGYTKDEHKKMDLHNNEIGRKLGADNLSAPEEKMAEIIYDEIMREDSLFVWLHE"
     CDS             complement(1536..3632)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 257.4; E-value:
                     4.6e-78)"
                     /gene_kind="transport"
                     /locus_tag="ctg112_2"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.2e-31, bitscore:
                     97.2, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKKVHYVSQLGSMDCGIACLTMILNYYGCKSDIVDIGAEIQIG
                     RDGMTLAQMKELAEKYGFKFAAYQYNHEEKNLIEYLPAILCNDSHYVVVDKTKKKGKYI
                     LFDPANGKRVVDFLELKNGYKDILVSVIPSRNIKKIKKTKFKIEVKFSQFMIAIMLMLM
                     CQLITLAVPMVVQKVIDSLSSAHITIHIWKITLLVLLIMCAHFVLSLLRQKILLNINMK
                     LFKTMISNMIHKIFRLDVSFFEWHSAGDIGNRFNSINQLNDILTNGFINIIIQGITSLV
                     CLAVMTSISPYLTAFVLVVSIIQIAIMILLNGKNLIKTKEYIYSQSTIQGELIDTLENI
                     MEIKCMGMDNAVKSNLQNSYSKLIERFKGKTRISNLMNSFSSTLNLIFPLMIYVIGSYS
                     VKQGGLTIGQLIAYATLVGYFTAPFTTVVLLLPSINSIKEVLLRYKELMIFRENYHTGV
                     LVPGKFENLKISSVSYCYNSGQAYALNNVSLDLRRGERIAIVGLSGSGKSTLIKAILGA
                     VDINQGCIEINNYDIRSMSKEQIYKWFSVVTQNPMCLNASIRKNIDIIGDAPDEKIWKV
                     LDIVALKEEVLSMPLGLDTLVGEGGQNISGGQKQRIAIARALLSDTEVVIFDEATSNLD
                     QLTEKKIYDNLRSTNKTQIIITHRLSSIRDTDYIYVLNRGSIIEQGTHLDLMKKKGWYF
                     ESIQ"
     CDS             complement(3675..6812)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     851.2; E-value: 1.8e-257)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_3"
                     /sec_met_domain="DUF4135 (E-value: 6.4e-105, bitscore:
                     340.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.1e-58, bitscore:
                     187.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNNCDNNSYFYERNYYKDVPIKDTQILEYWNNILGKDVIELID
                     KAYGVSIEQILFSEYSLNHKYISFATLNQEYSDMCNEKAISYLTKKGTKVLFDQFVLRF
                     LGYGKRVLERKSRKGYIVKVVQDCFLKNLAERILDVSLSTLIFEMYLAKEQGELRGNDE
                     AEEYKDYNQRFLGNDKYIKELFSIYPGLKRMLIELMENLANNYILLQERMEKDTLLLED
                     KFGGKKGWTEVKNIRTSGSDSHKKGNSVFLIQFQDGRKIVYKPHGLKVEKAYQSFLEFI
                     SSNCKKDFKQFLILDCGDYGWEEFVVNLPCNSEAEVRNYYYRIGVLVFCNYILNVNDIH
                     TENLIANGGYPVVVDAETVLDNKRDKKKKSGREKIYDKIHESVLYSGVLPFYKYTKNGK
                     GINMSALNGQEGEQYPILIPRLKNAGTSNMHYEYERPITQASNNLLRLGEKVKEPNQYI
                     DEICEGFFDAYTFCLDNKKLILNYVSIFENIEVRHLVQDTQRYSMLLHTSYNPDFLQDA
                     KDRQLFLCAVLKNVEQMQGNMEIAKLEIKDMLNMDIPYFYSNTSKEDLYGSEGEVVKNY
                     FAESSIQHLRNKICSMGKKDREEQIRFIKIILTDLNDVKVEKPKKDINELCISRSDNEH
                     GQKEYKKNAILKILHTLEQKAFYGDDGQDINWIGITSIGNSENSSWNIQPLGVYLYEGL
                     GGIALFYNALQQSDFDVDLSAACKAFETMMFQYTDDMLERSTDLEKESSGAYAGEASVI
                     YVYEVLYKITGKQKYLEYAEKHCKILEYALKADENNDLIYGNAGAVIVLLNLYHLAQKD
                     IYLQLACEAGNILIKNQNKGKWCCGNGQSLSGLSHGITGIIYALTKLNNEQFHIEYQKA
                     IHSGLIYENTMYSDKYNNWLDNREEAKKEENSDNRCMAAWCHGAPGILLARSKMYNLVK
                     DSSDYITVQCDIERALFATKMYGFTDNDCLCHGNLGNTEILLEYSKECNDEEVRHMMLS
                     ARTQIAMDIINENYDCARSYLHGYKIPGFMTGISGMGYSLLRDLYPELPCILALEI"
     CDS             complement(6929..7129)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg112_4"
                     /transl_table=11
                     /translation="MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSD
                     GSQFCTSTKECNWGTIMFVCC"
     CDS_motif       complement(6989..7129)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSDGS"
                     /locus_tag="ctg112_4_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6929..6988)
                     /prepeptide="core"
                     /locus_tag="ctg112_4_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="2129.5"
                     /monoisotopic_mass="2127.9"
                     /core_sequence="QFCTSTKECNWGTIMFVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEP
                     RVSDGS"
                     /leader_location="[6988:7129](-)"
     CDS             complement(7410..8195)
                     /locus_tag="ctg112_5"
                     /transl_table=11
                     /translation="MGNIISTELLKIKRYSVVKAGLVMMSLSVLMSCFYSTASTNKVWD
                     FQYFIQQVIISNCTLFFPIIITLVAVYIISRETTDDTLKSILTVPISYKKLLIAKFWLL
                     LFLTIVFSIFNALLSICFNAFLGFSGMNIHMMLMSAAQIIVSDILVYISVLPIIIVCAF
                     AEGKSLLGVAVAFIYGYFATMEGSMLNWFPIKAAMILVDPKCGSEYGITYKIPPAAMSI
                     IGVLVVSILLFQMLNRTKKNVYMKSKRKVKVKQTRRKGW"
     CDS             complement(8201..9010)
                     /locus_tag="ctg112_6"
                     /transl_table=11
                     /translation="MLDLVRCEFTKLKRRKIALMLIVLSCFFPLIVVITTKNGMSGDLS
                     THYLKMRFDLSFTMTQGYGLVFLAPCLIGMLATILFFMERDNDTFKNIRTVPVTITKMI
                     LAKICVLFIYGTLFSLASVSFTIFFSWILKVGIIYDLAYKLGFSIIFGLVITIASLPIV
                     VIIVYFNKSYLVSTLLAFFYSILNWGIIGLFETMAVKGTAKFLNLFPVICAMDWTSGKL
                     VDHVIKDNLSKEAYIMFPSDIYAFLVLGVTLFLSLMLMIRFYKKWTR"
     CDS             complement(9003..9926)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 179.5; E-value:
                     1.4e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg112_7"
                     /transl_table=11
                     /translation="MSQYIIQTRDLTKTYGEQKSVSNLNMHVRKGKIYGLLGRNGAGKT
                     TTMKMLLNLIEPTSGSIRIFNRDIRLEEKKILPRIGSLIESPGFYPNLTGTENLRIFAK
                     LRGIPRTDAIEQALKLVNLPYKDKKLYSQYSLGMKQRLAIALAVMHDPEILILDEPING
                     LDPIGIAEIRTFIEDLSKNRGKTILISSHILSEIAVLADDIGIIDKGVLIEEGSMKELE
                     EKNGKYVHFKVSDNAQAARILSVYYKESNFKVSGNQDINVYNLSISIPDIVRSFVQEGV
                     DVMDAHLCEDTLEDYFKKVTGGEGIA"
     CDS             complement(9959..10057)
                     /gene="allorf_09959_10057"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_09959_10057"
                     /protein_id="allorf_09959_10057"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIRSSIIFFVLNKLQGSCQVSVRFLSEKYIIL"
     CDS_motif       complement(10007..10057)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MIRSSIIFFVLNKLQGS"
                     /locus_tag="allorf_09959_10057_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9959..10006)
                     /prepeptide="core"
                     /locus_tag="allorf_09959_10057_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.20"
                     /molecular_weight="1762.1"
                     /monoisotopic_mass="1761.0"
                     /core_sequence="CQVSVRFLSEKYIIL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIRSSIIFFVLNKLQGS"
                     /leader_location="[10006:10057](-)"
                     /alternative_weights="1780.1"
     CDS             complement(10066..10983)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 151; E-value: 1e-45)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg112_8"
                     /transl_table=11
                     /translation="MKLFYVVLVILLFYNLGLTLYVFKINRRLKEFNQILLEIEKGQSK
                     QKFLLKKNNRIDQVGFRVNSILYKYEKRIEESNIELEANKQLMTSLSHDVRTPMTTLIG
                     YLDALDLKLVSSDKEEQYLRLAKEKAYDLKKYIEVLFEWFRINSDEEQLEIKAVDITEE
                     TRRIFLDWIPIIEEHRIGYNIEIPEKAIIVEIDEDCYMRAINNIVQNIFTHSKAANISI
                     TASEGNGKFRLEIGDDGIGIAKEDLNYIFERLYQCNKGRSGKGNGLGLNISKLLLEKMG
                     GTISAFSEPGKGTVFCIEFSVIQR"
     CDS             complement(10989..11678)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 193.2; E-value: 7.7e-59)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg112_9"
                     /transl_table=11
                     /translation="MRKDIIIIDDDRDLCTLLQESLLQENICADISCNGFDGIKSVKDK
                     EYQLVVLDVMMPGISGFEVLERIRDMSNVPILMLTAKDDSTSKVKGLRAGADDYLTKPF
                     EMEEFFARVLSLIRRYTRLNNMASKAILKYGDLRIDLESGIVELSGEELKLSAKEYDVL
                     IYLAKNQGKILTKKQIYENVWNEEYVYDDDNIMAVISRLRKKIERTAENSYIQTVRGLG
                     YRFNKEL"
ORIGIN
        1 gccattgctc acagttgcta cgacagccgc accgttggga agaaagataa ggtgtccttt
       61 gttgtgacac atattgatga agaacggaat gttgctgttg gcatcattac aaggattatc
      121 aaacaaaata tctgattacc aaaagcaata tgaaaaggag ctcactacat ccatttctta
      181 ttgcgataca agatattcca tgctatactg agcgagtata gctaatcgag aaagagatgc
      241 ggatgcaatt tcgaccagcc ctctagtttt taaaggaggg tgatgcccat gaacacaatg
      301 gaagtactca cattgctttt agtagttttt gcggctctga cttacataga taatcgacat
      361 gataagaaat agcatccacg ataaaccctg agaaagtttg atggatgcta tgtcttaaca
      421 tagaaaaaaa ttaaatttta ctgagggcat cagatcttgc atctgattac ctttcttaat
      481 tagattatac actgggggat atgagaaatc aagtccccct ttattattgt tattgtcatt
      541 acttaaacta aatcgacaaa taatatgttg ataaatattt ttctacagcc ccctcattct
      601 catttgacca tcatttaaca gatttcacat ctaattcatg gctatacatt agtacttggt
      661 tctcattctg attcttcttt caaatttagt cagagcagac atttttaacg actattattt
      721 ctattcaaaa acagtcacag atatctaaac atcaataaaa tatctgcgac tgtcttagag
      781 atatatttca tttcagttca tacgttctaa ctttttcatt catgcagcca tacaaacagc
      841 gaatcttctc tcattatctc gtcatatatg atttccgcca ttttctcttc tggtgcagat
      901 aggttatctg cacctaattt cctccctatt tcattgttat gtaaatccat ttttttgtgc
      961 tcatcttttg tatatccatc gctttcgttt ccagtagtat ctttatcttc atgtgctgtc
     1021 gcaaaaagct ctgctttttc acttcctatc aaaactgtca tttcggcatt ccatattccg
     1081 tgtctaaatg cgtcactcct gtcacccaaa ccattttttc cgaattttct ttcggtttgt
     1141 ttagtggcaa tttcctttgc tttattgact tttagtgcat caaacggata tcgaatcact
     1201 aattttttct cagaagaagt aagtgcgttc caaatgtcta tgacgccatc tttcttaata
     1261 gcatgaatct gatccataaa atcacttatc tgctgttcac tccattccgg atgttttgac
     1321 ttaacatcta aaatttgctt aacgatatcc tcaaactcat tagtttcatc aattataaaa
     1381 cctctagaac tcatactttc atttgaagca gcataaactg aaatgggaag tgatgcacta
     1441 atcagtacgc tcaccccaat aactatctct ttcttcttca tctgtaatac ctccccatac
     1501 aatggctttt catatcataa tttaattcct atctgtcatt gaatactctc aaaataccat
     1561 ccctttttct tcatcaaatc caaatgtgtt ccctgttcaa tgatgcttcc cctgttcaat
     1621 acatagatat aatccgtatc tcgaatagag gaaagtctat gagtaatgat aatttgcgtt
     1681 ttattggtag accttaggtt atcataaatt ttcttttctg taagctgatc cagattactg
     1741 gtagcttcat caaaaataac tacctccgta tcgctaagca gagctcttgc tatggcaata
     1801 cgctgttttt gaccacctga aatattttgt cctccttctc caacaagtgt atccaatccc
     1861 aacggcatac ttaaaacttc ctcttttaat gctacaatgt ctagtacctt ccatattttc
     1921 tcatccggag catcacctat aatatcaata ttctttctta tacttgcatt taagcacata
     1981 ggattttgag taactactga aaaccattta taaatctgtt ccttcgacat tgatctgata
     2041 tcataattat ttatctcaat acatccttga ttaatatcca cggcacccag tatggctttt
     2101 atcaaggttg attttccact acccgataaa ccaacaatag caattctctc gcctcgccta
     2161 agatcaagag aaacattatt caatgcgtat gcctgcccac tattgtagca atatgaaacc
     2221 gaacttattt ttaaattttc aaattttcca ggtacaagaa ctcccgtatg ataattttct
     2281 ctaaaaatca ttagttcctt ataacgtaaa agcacttctt taatactatt gatactcggt
     2341 aacaacaata caacggtagt aaaaggtgct gtaaaatatc ccactaaggt tgcataggct
     2401 ataagttgtc ctatcgttaa ccctccttgc ttcacactat aacttccaat cacgtaaatc
     2461 attaaaggga aaatcaagtt taaggttgag gaaaaactat tcatcaaatt actaattcga
     2521 gtttttccct tgaatctttc tattaactta ctataagaat tttgtaaatt tgatttaact
     2581 gcattatcca tccccataca ttttatttcc attatattct ccagagtatc tatcagttct
     2641 ccctgtattg tactctgtga gtatatatac tctttcgtct ttatgagatt tttaccattt
     2701 aataaaatca ttatggcgat ctgtataata gaaacaacta gaacaaatgc agtcaaatat
     2761 ggagatatac tggtcataac agctaaacat accaaggatg taatcccttg gattataatg
     2821 tttataaatc cattggtaag aatgtcgttc aactgattta tactattgaa acggttccct
     2881 atgtcacctg cggaatgcca ttcaaaaaaa cttacatcca aacggaaaat tttatgaatc
     2941 atattagaaa tcattgtttt aaaaagtttc atgttaatat tcaataaaat tttctgtctt
     3001 agtaagctca atacaaaatg ggcacacata atcagaagaa ctaaaagtgt aattttccat
     3061 atatgaattg taatatgggc agaagataaa ctatctatta ctttttgcac aaccattgga
     3121 acagctaatg taataagttg acacataagc atcaacataa ttgcaatcat aaattgagag
     3181 aattttacct ctattttaaa tttggttttt tttattttct taatatttct acttggaata
     3241 acggatacaa gaatatcctt gtatccgttt tttaattcta aaaaatcgac aactcttttt
     3301 ccatttgctg gatcaaacag aatatatttt cctttcttct tagttttatc aactaccaca
     3361 tagtgggaat cattacacaa aatggctgga agatactcta ttaagttttt ttcttcatga
     3421 ttatactggt atgcagcaaa tttaaatcca tacttttctg ctaattcttt catttgagct
     3481 aaggtcatac cgtctctgcc aatctgaatc tctgccccta tgtccacgat atcactttta
     3541 cacccgtaat aattaagaat cattgtcaga catgctatgc cacaatccat gcttcctagc
     3601 tgtgaaacat aatgcacttt tttttgaaac atcaagttcc tccctttgtt aaatattact
     3661 tagcaattac gctcctaaat ctccagagcc aaaatgcatg gtaattctgg gtacaaatct
     3721 cttaatagag agtatcccat tcctgagatt cctgtcataa atcctggtat cttataccca
     3781 tgcaaataag accttgcaca atcgtaattt tcatttataa tatccatagc aatttgtgtt
     3841 ctcgcagaca acatcatatg tcttacttct tcatcattac attcttttga atattcaagt
     3901 aatatttctg tattccccaa attcccatga catagacagt cattatctgt aaatccatac
     3961 atttttgtcg caaatagtgc acgttcaata tcacattgta ctgttatata atcactactg
     4021 tctttaacca ggttatacat cttacttctt gccaataaaa tccctggtgc cccatgacac
     4081 catgctgcca tgcatctatt atcagagttt tcttcttttt ttgcctcctc ccgattgtct
     4141 aaccaattat tatatttatc agaatacatg gtattttcat atattaatcc agagtgtatt
     4201 gccttttgat attcaatatg aaattgctca ttatttaact ttgtaagagc ataaattata
     4261 cctgtaattc catgtgacag cccagataag ctctgcccgt ttccgcagca ccacttaccc
     4321 ttattctgat tttttataag aatgttccct gcttcgcacg ccaattgcaa atatatatcc
     4381 ttttgagcta agtgataaag attaagaaga acaataacgg cacctgcatt accataaatc
     4441 agatcattat tttcatctgc tttcaatgca tactctaaaa ttttgcaatg tttttctgca
     4501 tattctaaat atttttgttt tcctgttatc ttatataaaa cttcgtatac atatataaca
     4561 gaagcttccc ccgcataagc accgctactt tccttttcta aatccgtgga tcgttccaac
     4621 atatcatcgg tatattgaaa catcatggtc tcaaatgctt tgcaggctgc tgacaaatcc
     4681 acatcaaaat ctgattgctg tagtgcatta taaaaaaggg caattcctcc taatccttca
     4741 tataaataaa cccctaatgg ttggatattc caagaagaat tttcagaatt tccaatagat
     4801 gttattccta tccaatttat atcctgccca tcatcaccat aaaaagcttt ttgctctaat
     4861 gtatgtaaaa tttttaatat ggcatttttt ttatattcct tttgtccatg ttcattatcg
     4921 cttctactta tacaaagttc atttatatct tttttaggtt tctcaacttt tacatcattc
     4981 aaatctgtta aaattatttt tataaatcta atctgttctt ctctatcttt cttgcccata
     5041 gaacagatct tatttctaag atgttgaata ctagactcag caaaatagtt cttcaccact
     5101 tccccttctg atccataaag atcttctttt gaagtattgc tataaaaata tggaatatcc
     5161 atattcagca tatcctttat ttccagtttt gcaatttcca tattcccttg catctgttcc
     5221 acatttttta acactgcaca caaaaatagt tgcctatctt tcgcatcttg aagaaaatcc
     5281 ggattgtatg atgtgtgcaa tagcatggaa taccgctgag tatcttggac taaatgccta
     5341 acttcaatat tttcaaatat cgaaacatag tttaatataa gcttcttatt gtccaaacaa
     5401 aatgtatatg cgtcaaaaaa accttcgcat atctcatcta tatactgatt aggttctttt
     5461 accttttccc ccagtctcag taaattatta ctagcttgag taataggtct ttcatattca
     5521 taatgcatat ttgatgtccc agcatttttt aatcttggaa tcagtattgg atattgctct
     5581 ccctcttggc cattaagagc actcatattt ataccttttc catttttagt gtatttataa
     5641 aaaggcagta ctccagaata caacactgat tcatgtatct tatcgtaaat tttttctcta
     5701 cctgattttt tctttttgtc ccttttatta tctaagacag tctcggcatc tacaacaacc
     5761 ggatatcccc cattagcaat aagattttca gtatgtatat cattgacatt taatatataa
     5821 ttgcaaaaaa caagcactcc tatccgataa taataattcc tgacttcagc ctcactgtta
     5881 caaggaagat taactacaaa ttcttcccat ccatagtccc cacaatctaa aatcaaaaat
     5941 tgcttaaagt cctttttaca attggaagaa ataaactcca aaaatgactg atatgctttc
     6001 tccaccttca gtccgtgtgg tttataaact atttttcttc catcttgaaa ctgaattaaa
     6061 aaaacactat ttcctttctt atgtgaatct gaaccactcg ttcttatgtt ttttacttca
     6121 gtccagccct ttttcccacc aaatttatct tctaaaagta aagtatcctt ttccattctt
     6181 tcctgcaata atatataatt atttgccaaa ttttccatta attctatcag cattctttta
     6241 agacctggat atatggaaaa taattctttt atatacttat cattaccaag aaatctctga
     6301 ttatagtctt tatattcttc tgcttcatca tttcctctaa gttctccttg ttcttttgct
     6361 aaatacattt caaaaataag agtgcttaaa gaaacatcta aaatcctttc cgctaaattt
     6421 ttcaaaaaac agtcctgaac tactttaaca atatatcctt ttctactctt tctttctaaa
     6481 acccgtttcc catatcccag aaacctgaga acaaattgat caaataatac ttttgttcct
     6541 tttttagtca aataggatat agccttctca ttacacatat cagaatattc ctgatttaac
     6601 gttgcaaagc taatatattt atgatttaac gaatactctg aaaataatat ctgctctata
     6661 gaaaccccat aagccttatc tattaattca ataacatctt tacctaaaat gttattccaa
     6721 tattctaata tttgagtatc tttgattgga acatccttat aataatttct ttcataaaaa
     6781 taggaattat tgtcacaatt atttttatcc ataataatct cctccattac gtaaaaaatt
     6841 ttgaatttgc atatgatatc tatgcataga agccaaacct attcattcag tagtcatcat
     6901 acctgtggtt tcataccact ctcataaact aacagcaaac aaacataatt gttccccagt
     6961 tacattcttt tgttgatgta cagaactgag agccatcgga aactcttggt tcaccagcac
     7021 ctgcggaaaa attgtttaaa tccgcctctt taatttcctt cattacattt cctgccggat
     7081 tcataaaatt ttctggtctt gtcattggat ttctataatt tttcttcata aggcacgctc
     7141 ctaactgctt cttgcataga taccatatgt aaattcaaaa tgtctatatc tatacgattt
     7201 aatttttcac aaaatactgc aggaatacag aacccttcag gttcatccta agatatttat
     7261 tttttcattt ctcatttcct taaaaggttc tgttaagttc acttgactag cagtatgtat
     7321 tttctcttct ccttccttac aaacatatat taaaattgtt tatgattatg attacggaca
     7381 acatttcttt acattcaatc caccattttt taccaccctt tccgtcttgt ttgttttacc
     7441 tttacttttc tttttgattt catataaaca ttctttttgg ttctgtttag catttgaaac
     7501 aatagtatgg aaaccaccaa aaccccaatt atagacatcg ccgcaggagg aattttatat
     7561 gttattccat attcgcttcc gcatttagga tcaacaagta tcattgcagc cttgattgga
     7621 aaccaattaa gcatacttcc ttccattgtt gcaaaatatc cgtagatgaa tgcaacggca
     7681 actcccagca atgattttcc ttctgcaaaa gcacaaacaa taataatggg aagtactgat
     7741 atatacacca atatgtcaga tacaataatc tgagcggctg acatcagcat catatgaata
     7801 ttcattccag aaaatcctaa aaaagcatta aaacatattg acaaaagagc gttaaaaata
     7861 ctaaatacta tagttaaaaa taaaagcagc caaaatttag caataagtaa ctttttatat
     7921 gaaataggta ctgttaaaat agattttaat gtatcatctg ttgtttccct ggaaataatg
     7981 tacacagcga ctaatgtaat aataatcggg aaaaataatg tacaattact aataattacc
     8041 tgctgtataa aatactgaaa atcccatact ttatttgtgc ttgcagttga ataaaagcaa
     8101 ctcattaaca cagatagcga catcataact aatccagctt ttacaactga atatctttta
     8161 atttttaata actctgttga tataatattt cccatttaaa ttacctcgtc cattttttat
     8221 aaaatctaat cataagcatt aaagataaga acaatgttac tcctaatacc aaaaatgcat
     8281 aaatatctga cggaaacata atatatgctt cttttgacaa attatctttt attacatgat
     8341 ctaccagttt accgcttgtc cagtccatcg cacatataac tggaaataga tttagaaatt
     8401 ttgcggtacc tttcactgcc attgtttcaa ataaaccgat aattccccaa tttagaatcg
     8461 aataaaaaaa tgccaacaat gtagacacta aataggattt attaaaatat actattataa
     8521 ccacaatagg aagtgacgct atcgttatca caagcccaaa tataatacta aatcctagct
     8581 tgtatgctaa atcatatata ataccaacct tcaatatcca tgaaaagaat attgtaaatg
     8641 atacactcgc caggctaaaa agagtaccat atataaaaag tacacagatc tttgcaagga
     8701 tcattttggt aattgtcacg ggcactgttc taatattttt aaatgtatca ttatctcgtt
     8761 ccataaagaa caagattgtc gcaagcattc ctattaaaca aggtgcaagg aatacaagac
     8821 catagccctg tgtcatagta aaggataaat caaacctcat tttcaaataa tgtgtgctca
     8881 gatcaccaga catcccgttc ttagttgtta taaccacaat taaggggaaa aaacatgata
     8941 atacaatcag catgagcgcg attttccttc ttttcaattt tgtaaactca catctgacta
     9001 aatcaagcaa ttccttcccc tcctgtcact tttttaaaat agtcctctaa agtatcttca
     9061 cacaaatgag cgtccatcac gtctactcct tcttgaacaa aggaacgaac tatatctggt
     9121 attgatatac tgagattata cacatttata tcttggtttc ctgatacctt aaaatttgat
     9181 tctttataat acactgacag tattcttgct gcttgggcat tatcagaaac cttgaagtgt
     9241 acatattttc catttttttc ttctaattcc ttcatacttc cctcttcaat gagtacgcct
     9301 ttatcaataa taccaatatc gtctgctaaa acagcaattt ctgaaagtat atggctagag
     9361 atcaatatag ttttccctct atttttagat aaatcttcta taaatgttct tatttctgcg
     9421 attcctatcg gatctaagcc attaattggt tcatccaaaa ttaatatttc tggatcatgc
     9481 attaccgcta atgctatagc taatcgctgt ttcattccta atgaatactg cgaatataac
     9541 tttttatctt tgtagggtaa attaacaagt tttaatgcct gttcgatagc atcagttctt
     9601 gggattcctc tcaatttcgc aaaaattcta agattttccg tacctgtcaa attagggtaa
     9661 aatccaggac tttcaatcag tgatcctatt cgaggtaata tttttttctc ttcaagcctt
     9721 atatctctat taaaaatacg tatggaacct gatgtcggtt ctatgaggtt tagcagcatt
     9781 ttcatagttg tggtttttcc agctccattt ctccctaaga gtccatatat ctttcctttt
     9841 cttacatgca tatttagatt ggaaacactt ttctgttctc catatgtttt agttaaatca
     9901 cgtgtttgta taatgtattg tgacatttgg tttttctcct ttcagaatct tctatgtttt
     9961 acagtataat atatttttct gacaggaacc tgacagaaac ctgacaagaa ccttgtaatt
    10021 tatttaatac gaaaaagatg atactcgaac gtatcatctt ttttgttacc tttgtataac
    10081 tgaaaattca atacaaaata ctgttccttt acccggttca ctaaatgcac taattgtccc
    10141 acccattttc tctagcaata attttgaaat atttaatccc agtccattcc cttttccgga
    10201 tcttccttta ttacactggt ataatctttc aaaaatataa ttcaaatctt cctttgctat
    10261 ccctatccca tcatcaccta tctcgagtct aaatttacca ttcccctctg atgctgttat
    10321 tgatatgttt gctgctttgc tatgagtaaa aatattctgc acaatattat ttatagccct
    10381 catataacaa tcctcatcaa tctcaacaat tatagctttc tcaggaattt ctatattata
    10441 tcctattcga tgttcttcta ttatagggat ccaatccaaa aaaatccttc tggtttcttc
    10501 agtaatgtca actgctttta tttccaactg ttcctcatct gaattaatcc taaaccactc
    10561 gaataacact tcgatatatt tttttaagtc atacgccttt tctttcgcta gtcttagata
    10621 ttgttcctct ttatctgaac ttaccagttt taaatctaga gcgtccaaat accctattaa
    10681 ggttgtcatg ggtgttctga catcatgtga taaacttgtc atgagttgct tatttgcttc
    10741 caactctatg ttactctctt cgatcctttt ttcatattta tacaatatag aatttactct
    10801 aaatccaact tgatctatcc tattattttt tttcaataga aacttttgtt tgctttgacc
    10861 tttctctatt tctaaaagta tttgattgaa ctcttttagt cttctattaa ttttaaacac
    10921 ataaagtgtc aatcccaaat tataaaataa aagtatgact agcaccacat aaaataattt
    10981 catttatctc ataactcctt attgaatcta tatccaagac ctcttacagt ctgaatatac
    11041 gaattttctg ctgttcgctc tattttcttt ctcaatctgc taataactgc cattatgtta
    11101 tcatcatcat atacatactc ttcgttccaa acattttcgt atatttgttt cttcgtgaga
    11161 atttttcctt gattttttgc aagatatata agtacatcat attcttttgc agataattta
    11221 agctcttcac cagacaattc tactatgcca ctttctaagt caattcttaa atcgccatat
    11281 ttcaaaattg ctttactagc catattattt aaacgtgtgt aacgtcttat tagagataat
    11341 actcttgcaa aaaactcttc catttcaaaa ggttttgtca aataatcatc agctcccgcc
    11401 cgcaaccctt ttacttttga ggtgctgtca tctttcgctg taagcattag tattggtaca
    11461 ttactcatgt ctcgtattct ttctaaaact tcaaaaccac tgattcctgg catcatcaca
    11521 tccaatacaa ctaattgata ttccttatct tttactgatt ttatcccatc aaaaccgttg
    11581 catgaaatat ctgcacaaat attttcttgc aaaagactct cttgcaagag tgtacataaa
    11641 tccctatcat catcaataat tataatatct tttctcatct caagcctcca gtaatatgta
    11701 tatctcttca aattgattgc aacaattata ttggtaatta ttttatcact atattaaccg
    11761 tttgtatctt acaatattct tgtaattcat atatcgaacc attttggcta actctttata
    11821 tatcaaattt ttatttcttc atctcaactt gacaaacctc tacaattaaa aaaaattcac
    11881 ccatactaga ataatctgac aacgattcca ggtaggggaa catattctgg tccgaatctt
    11941 aactatcccg ggagattccc cagaaacgct ctccatccat gcagatgtaa aaatcgtgga
    12001 aggcaacacc agcaaagaaa atctgaaaag ttgtcgggta cagggaaaat atgccggaac
    12061 ggtggaagac atccacaaag gaactgtttt tgtccggtta gaattgggcg tcaacgccat
    12121 tgctcacagt tgctacgaca gccgcaccgt tgggaagaaa gataaggtgt cctttgttgt
    12181 gacacatatt gatgaagaac ggaa
//
