GCA_000484655.1 - 12 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaKCPIDHJJ_2 (original name was: gnl|Prokka|KCPIDHJJ_2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS	1	35,569	dipeptide aldehydes	NRP	47%

gnlProkkaKCPIDHJJ_7 (original name was: gnl|Prokka|KCPIDHJJ_7)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	cyclic-lactone-autoinducer	81,017	93,723

gnlProkkaKCPIDHJJ_27 (original name was: gnl|Prokka|KCPIDHJJ_27)

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	lanthipeptide-class-ii	10,539	33,505	xantholipin	Polyketide	6%

gnlProkkaKCPIDHJJ_29 (original name was: gnl|Prokka|KCPIDHJJ_29)

Region	Type	From	To	Most similar known cluster		Similarity
Region 29.1	ranthipeptide	10,237	31,825

gnlProkkaKCPIDHJJ_39 (original name was: gnl|Prokka|KCPIDHJJ_39)

Region	Type	From	To	Most similar known cluster		Similarity
Region 39.1	ranthipeptide	1	20,410

gnlProkkaKCPIDHJJ_41 (original name was: gnl|Prokka|KCPIDHJJ_41)

Region	Type	From	To	Most similar known cluster		Similarity
Region 41.1	cyclic-lactone-autoinducer	1	15,664

gnlProkkaKCPIDHJJ_79 (original name was: gnl|Prokka|KCPIDHJJ_79)

Region	Type	From	To	Most similar known cluster		Similarity
Region 79.1	cyclic-lactone-autoinducer	1	15,551

gnlProkkaKCPIDHJJ_95 (original name was: gnl|Prokka|KCPIDHJJ_95)

Region	Type	From	To	Most similar known cluster		Similarity
Region 95.1	cyclic-lactone-autoinducer	1	15,111

gnlProkkaKCPIDHJJ_112 (original name was: gnl|Prokka|KCPIDHJJ_112)

Region	Type	From	To	Most similar known cluster		Similarity
Region 112.1	lanthipeptide-class-ii	1	12,204	ruminococcin A	RiPP:Lanthipeptide	14%

gnlProkkaKCPIDHJJ_142 (original name was: gnl|Prokka|KCPIDHJJ_142)

Region	Type	From	To	Most similar known cluster		Similarity
Region 142.1	cyclic-lactone-autoinducer	1	6,661

gnlProkkaKCPIDHJJ_148 (original name was: gnl|Prokka|KCPIDHJJ_148)

Region	Type	From	To	Most similar known cluster		Similarity
Region 148.1	lanthipeptide-class-ii	1	6,047

gnlProkkaKCPIDHJJ_195 (original name was: gnl|Prokka|KCPIDHJJ_195)

Region	Type	From	To	Most similar known cluster		Similarity
Region 195.1	cyclic-lactone-autoinducer	1	1,522

Compact view

gnlProkkaKCPIDHJJ_2 - Region 1 - NRPS

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Location: 1 - 35,569 nt. (total: 35,569 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 35569:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg2_9

AMP-binding (22..421): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLTDGGISK
Nearest Stachelhaus code(s):: Leu or Trp DVLTDGGISK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1035..1423): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAMFSGAIFK
Nearest Stachelhaus code(s):: Leu or Trp DAMFSGAIFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2029..2420): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAITTGGVSK
Nearest Stachelhaus code(s):: Leu or Trp DAITTGGVSK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaKCPIDHJJ_7 - Region 1 - cyclic-lactone-autoinducer

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Location: 81,017 - 93,723 nt. (total: 12,707 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKCPIDHJJ_27 - Region 1 - lanthipeptide-class-ii

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Location: 10,539 - 33,505 nt. (total: 22,967 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptide(s) for ctg27_22

ctg27_19

Leader:

MKTCSERNEQRINSLQLSESLEDEIKELDGKNVEAGDVIFT

Core:

TDTSSFLTIVCC

Core with dehydrations:

DhbDDhbDhaDhaFLDhbIVCysCys

antiSMASH-DB 4.0 matches for ctg27_19

100.0% NZ_CP102267.1and 2 others:

NZ_JADMOE010000006.1 Lanthipeptides: I2G55_RS05425_lanthipeptideNZ_LT635469.1 Lanthipeptides: BQ7352_RS14540_lanthipeptide

Lanthipeptides: NQ550_RS10225_lanthipeptide

1

TDTSSFLTIVCC

12

TDTSSFLTIVCC

1

TDTSSFLTIVCC

12

50.0% NZ_CP113781.1: Lanthipeptides: GGADHKLB_RS14125_lanthipeptide

2

DTSSFLTIVCC

12

+ + FLTI+CC

2

NCTHFLTILCC

12

40.0% NZ_AP025566.1: Lanthipeptides: MWL92_RS00840_lanthipeptide

4

SSFLTIVCC

12

+SF TI+CC

7

TSFCTIICC

15

with 10 more sequence matches

33.3% NZ_CP036524.1: Lanthipeptides: LAJLEIBI_RS18025_lanthipeptide

4

SSFLTIVCC

12

++F TI+CC

7

TTFFTIICC

15

31.6% NZ_CP036170.1: Lanthipeptides: HDCHBGLK_RS18795_lanthipeptide

4

SSFLTIVCC

12

+FLTI CC

11

GTFLTIYCC

19

29.2% NZ_CP048626.1: Lanthipeptides: GXM18_RS04600_lanthipeptide

2

DTSSFLTIVCC

12

D +SF TI CC

14

DNASFFTIFCC

24

26.9% NZ_CP070036.1and 3 others:

NZ_JADMPO010000043.1 Lanthipeptides: I2I27_RS16805_lanthipeptideNZ_JADNGF010000061.1 Lanthipeptides: I2E06_RS15650_lanthipeptideNZ_JAQMLK010000037.1 Lanthipeptides: PNW18_RS16660_lanthipeptide

Lanthipeptides: I6K72_RS03970_lanthipeptide

4

SSFLTIVCC

12

S+FLTI CC

18

SAFLTIYCC

26

20.6% NZ_JADPCB010000035.1: Lanthipeptides: I4W51_RS14990_lanthipeptide

3

TSSFLTIVCC

12

T +FLTI+CC

25

TGAFLTILCC

34

17.9% NZ_CP094681.1: Lanthipeptides: K5I26_RS05295_lanthipeptide

1

TDTSSFLTIVCC

12

+D + FLTI CC

28

SDCALFLTIFCC

39

17.9% NZ_JAOQJV010000004.1: Lanthipeptides: OCV65_RS05205_lanthipeptide

4

SSFLTIVCC

12

S FLTI+CC

31

SGFLTIICC

39

17.6% NZ_MCGI01000004.1and 1 other:

NZ_MPDJ01000004.1 Lanthipeptides: BLA28_RS33805_lanthipeptide

Lanthipeptides: BEH84_RS33640_lanthipeptide

1

TDTSSFLTIVCC

12

T+++ FL+I CC

23

TESTPFLSIFCC

34

15.8% NZ_LT969517.1and 1 other:

NZ_QVLV01000012.1 Lanthipeptides: DXC51_RS29565_lanthipeptide

Lanthipeptides: C1733_RS32195_lanthipeptide

1

TDTSSFLTIVCC

12

T ++ FL+I CC

27

TASTGFLSIFCC

38

15.4% NZ_JADNBM010000025.1and 2 others:

NZ_JAQDZW010000013.1 Lanthipeptides: PGT55_RS13345_lanthipeptideNZ_QVMC01000003.1 Lanthipeptides: DWV46_RS15805_lanthipeptide

Lanthipeptides: I2A62_RS14145_lanthipeptide

4

SSFLTIVCC

12

++FLTI CC

31

TAFLTIFCC

39

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg27_19 - Class II

Cleavage pHMM score: -4.00

RODEO score: 0

Monoisotopic mass: 1198.6 Da

Molecular weight: 1199.4 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 1217.4 Da N = 1; 1235.4 Da N = 2; 1253.4 Da N = 3

gnlProkkaKCPIDHJJ_29 - Region 1 - ranthipeptide

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Location: 10,237 - 31,825 nt. (total: 21,589 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

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KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKCPIDHJJ_39 - Region 1 - ranthipeptide

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Location: 1 - 20,410 nt. (total: 20,410 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKCPIDHJJ_41 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 15,664 nt. (total: 15,664 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKCPIDHJJ_79 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 15,551 nt. (total: 15,551 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKCPIDHJJ_95 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 15,111 nt. (total: 15,111 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKCPIDHJJ_112 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 12,204 nt. (total: 12,204 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptide(s) for ctg112_3

ctg112_4

Leader:

MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSDGS

Core:

QFCTSTKECNWGTIMFVCC

Core with dehydrations:

QFCysDhbDhaDhbKECysNWGDhbIMFVCysCys

MIBiG 3.1 matches for ctg112_4

26.3% BGC0000503 (cinA): Lanthipeptide: cinnamycin

7

KECNWGTIMFVC

18

+ C++G FVC

3

QSCSFGPFTFVC

14

20.0% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

2

FCTSTKEC

9

+CT TKEC

18

WCTLTKEC

25

17.9% BGC0000517 (BAB04173.1): Lanthipeptide: haloduracin β or haloduracin α

2

FCTSTKEC

9

+CT T EC

16

YCTLTVEC

23

with 3 more sequence matches

13.6% BGC0000553 (SSGG_RS09925): Lanthipeptide: SRO15-2212

9

CNWGTIMFVCC

19

C + ++ V C

10

CEYSSLSVVLC

20

12.8% BGC0001229 (SBI_06990): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

3

CTSTKEC

9

CT +KEC

28

CTLSKEC

34

10.8% BGC0001229 (SBI_06989)and 1 other:

BGC0002110 (QKV49894.1) Lanthipeptide: birimositide

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

2

FCTSTK

7

FC +TK

27

FCPTTK

32

antiSMASH-DB 4.0 matches for ctg112_4

100.0% NZ_CP102267.1and 11 others:

NZ_FMUW01000051.1 Lanthipeptides: BLP57_RS16830_lanthipeptideNZ_JAQDBP010000004.1 Lanthipeptides: PGY07_RS07130_lanthipeptideNZ_JAQEHQ010000024.1 Lanthipeptides: PGR68_RS13915_lanthipeptideNZ_JAQESL010000043.1 Lanthipeptides: PG840_RS15980_lanthipeptideNZ_JAQESS010000001.1 Lanthipeptides: PG808_RS00050_lanthipeptideNZ_LN913006.1 Lanthipeptides: BN3261_RS01470_lanthipeptideNZ_QRPQ01000011.1 Lanthipeptides: DWZ74_RS14610_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03120_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16305_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06255_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03580_lanthipeptide

Lanthipeptides: NQ550_RS04155_lanthipeptide

1

QFCTSTKECNWGTIMFVCC

19

QFCTSTKECNWGTIMFVCC

1

QFCTSTKECNWGTIMFVCC

19

42.9% NZ_QRHZ01000008.1and 2 others:

NZ_QSRF01000021.1 Lanthipeptides: DXC87_RS15310_lanthipeptideNZ_QUEQ01000033.1 Lanthipeptides: DXA48_RS19000_lanthipeptide

Lanthipeptides: DW272_RS13830_lanthipeptide

2

FCTSTKECNWGTIMFVCC

19

FCTST ECN GT+ CC

11

FCTSTGECNMGTLNIFCC

28

40.0% NZ_JAFCGV010000005.1: Lanthipeptides: JQI09_RS04275_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT FVCC

7

TATSECYLGTFAFVCC

22

with 18 more sequence matches

40.0% NZ_WBPF01000002.1: Lanthipeptides: F8162_RS00195_lanthipeptide

1

QFCTSTKECNWGT--IMFVCC

19

QF T + EC+W T +F CC

4

QFDTISHECHWNTWQFLFTCC

24

36.0% NZ_CP045267.1and 1 other:

NZ_CP045267.1 Lanthipeptides: FDZ14_RS00155_lanthipeptide

Lanthipeptides: FDZ14_RS00155_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT F CC

7

TATSECYLGTFAFACC

22

34.6% NZ_CP117876.1: Lanthipeptides: PQ460_RS01735_lanthipeptide

4

TSTKECNWGTIMFVCC

19

T+T EC GT+ F+CC

7

TATSECYLGTVAFICC

22

33.3% NZ_CYXV01000003.1: Lanthipeptides: ARB75_RS04585_lanthipeptide

3

CTSTKECNWGTIMFVCC

19

CT T ECN GT + CC

12

CTLTGECNIGTHIKFCC

28

29.2% NC_012470.1and 42 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08895_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02930_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08675_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05705_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08735_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08985_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01075_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09255_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08770_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08920_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02160_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09650_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03445_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08815_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03175_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02475_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08475_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09585_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09025_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08485_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08495_lanthipeptideNZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS10120_lanthipeptideNZ_CP018188.1 Lanthipeptides: BSR19_RS11185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05190_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02600_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06670_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07260_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07305_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09825_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05340_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09695_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10860_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05070_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06745_lanthipeptideNZ_NWMU01000024.1 Lanthipeptides: CO197_RS09155_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04325_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05570_lanthipeptide

Lanthipeptides: SZO_RS10260_lanthipeptide

4

TSTKECNWGTI--MFVCC

19

T + EC W ++ +F CC

7

TISAECRWNSLQAIFTCC

24

29.2% NZ_ALSD01000046.1and 5 others:

NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06795_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS10995_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS1000000113590_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03150_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS11590_lanthipeptide

Lanthipeptides: SAG0161_RS1000000124770_lanthipeptide

4

TSTKECNWGTI--MFVCC

19

T + EC W ++ +F CC

7

TISAECRWNSLQAIFSCC

24

27.6% NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

1

QFCTSTKEC

9

QFCT TKEC

15

QFCTLTKEC

23

26.3% NZ_CP059557.1: Lanthipeptides: H2Q94_RS19875_lanthipeptide

7

KECNWGTIMFVC

18

+ C+WG + VC

3

QSCSWGPVTAVC

14

25.0% NC_021362.1and 29 others:

NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide

Lanthipeptides: BALI_RS00925_lanthipeptide

1

QFCTSTKEC

9

Q+CT TKEC

15

QWCTLTKEC

23

24.1% NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

1

QFCTSTKEC

9

+FCT TKEC

15

RFCTLTKEC

23

21.6% NZ_CP016767.1: Lanthipeptides: BCV50_RS18735_lanthipeptide

1

QFCTSTKECNWGTI

14

Q+CT + EC +GTI

21

QYCTVSAEC-FGTI

33

20.6% NZ_JAESIP010000017.1and 3 others:

NZ_LT907978.1 Lanthipeptides: EHLA_RS12685_lanthipeptideNZ_QRYY01000029.1 Lanthipeptides: DWW21_RS18370_lanthipeptideNZ_SPFW01000044.1 Lanthipeptides: FGQ81_RS16590_lanthipeptide

Lanthipeptides: JMK14_RS12260_lanthipeptide

1

QFCTSTKECNWGTIM

15

+ CT T EC TI+

18

RLCTGTAECPIMTII

32

19.2% NZ_CZAY01000009.1and 12 others:

NZ_CZBA01000009.1 Lanthipeptides: ARA06_RS08755_lanthipeptideNZ_CZBB01000003.1 Lanthipeptides: ARA29_RS04330_lanthipeptideNZ_JADPDU010000003.1 Lanthipeptides: I4V06_RS02990_lanthipeptideNZ_JAOQJU010000001.1 Lanthipeptides: OCV99_RS00835_lanthipeptideNZ_JAQCSY010000025.1 Lanthipeptides: PGZ10_RS13865_lanthipeptideNZ_JAQEDC010000020.1 Lanthipeptides: PHA23_RS12680_lanthipeptideNZ_QRZZ01000001.1 Lanthipeptides: DWV87_RS01465_lanthipeptideNZ_QSUB01000001.1 Lanthipeptides: DXB81_RS03120_lanthipeptideNZ_QUCI01000019.1 Lanthipeptides: DW648_RS14740_lanthipeptideNZ_QULD01000003.1 Lanthipeptides: DXB83_RS07060_lanthipeptideNZ_QULI01000007.1 Lanthipeptides: DXB71_RS08970_lanthipeptideNZ_SLZV01000043.1 Lanthipeptides: EDD74_RS14380_lanthipeptide

Lanthipeptides: ARA07_RS06830_lanthipeptide

2

FCTSTKECNWGTIMFVCC

19

CTST EC +GT++ CC

32

LCTSTAECYFGTLLKPCC

49

17.5% NZ_CM001792.1and 1 other:

NZ_CM001792.1 Lanthipeptides: C794_RS17980_lanthipeptide

Lanthipeptides: C794_RS17980_lanthipeptide

2

FCTSTKEC

9

FCT TKEC

26

FCTITKEC

33

17.1% NZ_FQZK01000006.1and 2 others:

NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptideNZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptide

Lanthipeptides: BUE45_RS13060_lanthipeptide

1

QFCTSTKECN

10

+FCT T ECN

26

RFCTVTVECN

35

16.7% NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21845_lanthipeptide

Lanthipeptides: CN325_RS21845_lanthipeptide

1

QFCTSTKEC

9

++CT++KEC

16

KYCTASKEC

24

15.8% NZ_BMRY01000003.1and 28 others:

NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12370_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS18205_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptide

Lanthipeptides: IE140_RS12370_lanthipeptide

1

QFCTSTKEC

9

FCT+T EC

25

NFCTATAEC

33

14.7% NZ_CAKMMP010000011.1and 5 others:

NZ_CP018620.1 Lanthipeptides: BS614_RS05680_lanthipeptideNZ_CP062165.1 Lanthipeptides: JNUCC31_RS16755_lanthipeptideNZ_FMVM01000006.1 Lanthipeptides: BLQ13_RS10365_lanthipeptideNZ_RIAS01000010.1 Lanthipeptides: EC604_RS18225_lanthipeptideNZ_VEJI01000010.1 Lanthipeptides: FS576_RS22075_lanthipeptide

Lanthipeptides: L6H98_RS19925_lanthipeptide

2

FCTSTKECNWGTI

14

FCT + EC++ ++

13

FCTVSHECHYNSV

25

allorf_00018_00122

Leader:

MIILVMMPTA

Core:

TFRSSSICVTTKDTLSFFPTVRLS

Core with dehydrations:

DhbFRDhaDhaDhaICysVDhbDhbKDDhbLDhaFFPDhbVRLDha

MIBiG 3.1 matches for allorf_00018_00122

10.3% BGC0001229 (SBI_06990): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

14

TLSFFPTVRL

23

T+S TV++

1

TISPIDTVKI

10

antiSMASH-DB 4.0 matches for allorf_00018_00122

29.2% NZ_CP072827.1: Lanthipeptides: allorf_1258365_1258535_lanthipeptide

8

CVTTKDTLSFFPTVR

22

CV T D+L F R

1

CVQTSDSLRLFRRRR

15

10.5% NZ_BMJA01000007.1: Lanthipeptides: allorf_031163_031396_lanthipeptide

1

TFRSSSICVTTKDTLSFFP

19

+ S +CV+ + L+ FP

35

ALQRSRMCVSKQSVLASFP

53

allorf_09959_10057

Leader:

MIRSSIIFFVLNKLQGS

Core:

CQVSVRFLSEKYIIL

Core with dehydrations:

CysQVDhaVRFLDhaEKYIIL

antiSMASH-DB 4.0 matches for allorf_09959_10057

100.0% NZ_CP102267.1and 7 others:

NZ_JAQDBP010000004.1 Lanthipeptides: allorf_177044_177142_lanthipeptideNZ_JAQEHQ010000024.1 Lanthipeptides: allorf_20164_20253_lanthipeptideNZ_JAQESL010000043.1 Lanthipeptides: allorf_02084_02182_lanthipeptideNZ_JAQESS010000001.1 Lanthipeptides: allorf_017059_017148_lanthipeptideNZ_LN913006.1 Lanthipeptides: allorf_0097924_0098022_lanthipeptideNZ_QRPQ01000011.1 Lanthipeptides: allorf_103379_103477_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: allorf_092199_092297_lanthipeptide

Lanthipeptides: allorf_0889319_0889417_lanthipeptide

1

CQVSVRFLSEKYIIL

15

CQVSVRFLSEKYIIL

1

CQVSVRFLSEKYIIL

15

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg112_4 - Class II

Cleavage pHMM score: -6.40

RODEO score: 0

Monoisotopic mass: 2127.9 Da

Molecular weight: 2129.5 Da

Number of bridges: 4

allorf_00018_00122 - Class II

Cleavage pHMM score: -4.80

RODEO score: 0

Monoisotopic mass: 2512.4 Da

Molecular weight: 2513.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2531.9 Da N = 1; 2549.9 Da N = 2; 2567.9 Da N = 3; 2585.9 Da N = 4; 2604.0 Da N = 5; 2622.0 Da N = 6; 2640.0 Da N = 7; 2658.0 Da N = 8; 2676.0 Da N = 9

allorf_09959_10057 - Class II

Cleavage pHMM score: -5.20

RODEO score: 0

Monoisotopic mass: 1761.0 Da

Molecular weight: 1762.1 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1780.1 Da N = 1

gnlProkkaKCPIDHJJ_142 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 6,661 nt. (total: 6,661 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaKCPIDHJJ_148 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 6,047 nt. (total: 6,047 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg148_4

ctg148_3

Leader:

MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG

Core:

TIVCC

Core with dehydrations:

DhbIVCysCys

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg148_3 - Class II: Cleavage pHMM score: -5.90; RODEO score: 0; Monoisotopic mass: 519.2 Da; Molecular weight: 519.7 Da; Number of bridges: 1

gnlProkkaKCPIDHJJ_195 - Region 1 - cyclic-lactone-autoinducer

Download region GenBank file

Download region SVG

Location: 1 - 1,522 nt. (total: 1,522 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.