LOCUS       c00032_gnlPro..        16486 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCPIDHJJ_32.
ACCESSION   c00032_gnlPro..
VERSION     c00032_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 16:48:00
            Original ID  :: gnl|Prokka|KCPIDHJJ_32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16486
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16486
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3471:6486]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3472..6486
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16486
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16486
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             358..726
                     /locus_tag="ctg32_1"
                     /transl_table=11
                     /translation="VEDAELRNILFSIQGSIAGFQNDMSDVKNDIADMKTDIANMKTDI
                     TNMKADITNMKSDIVQLKGSVKTIELKLENEIDRKISALFDARMDELRYRKENKETREK
                     VFELDMRVDNLEKAIMPA"
     CDS             1411..3066
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_2"
                     /sec_met_domain="HMGL-like (E-value: 8.1e-76, bitscore:
                     246.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNPSKYQRQYFMPPVKCMKWAEKEYVDKAPVWCSVDLRDGNQAL
                     VIPMSLEQKIEFFKLLVKIGFKEIEVGFPAASETEYEFLRTLIEQNLIPQDVTIQVLTQ
                     AREHIIRKTFEAVKGAPKAIVHVYNSTSVAQREQVFKKSKEEILKIAVDGAALLKKLAD
                     ETEGNFQFEYSPESFTGTEPEYALEVCNAVLDVWQPTADNKCIINLPVTVQHSMPHVYA
                     SQVEYMCENLKYRENVIVSLHPHNDRGCGVADSEMGLLAGADRIEGTLFGNGERTGNVD
                     IVTLGMNMYSQGVDPKLDFSDMPHICEIYEECTGMKVGERSPYSGALVFAAFSGSHQDA
                     IAKGMHWRDDKDPDHWNVPYLPIDPTDVGRNYDADVIRINSQSGKGGVGYILETKFGLN
                     LPPKMREAMGYATKAVSDHKHKELHPDEIFNLFKQTFENITEPYSINEVHFQQKDGGIV
                     TKVTSTFRGKTITTEASGNGRLDAVSNALKKAYELKYSLETYQEHALERSSSSKAIAYV
                     GIKKPDGTLAWGAGVDADIIRASIDALVTAINNR"
     CDS             3472..5727
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_3"
                     /sec_met_domain="Gly_radical (E-value: 3e-41, bitscore:
                     131.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.1e-268, bitscore:
                     881.3, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFEQWNGFKGNRWKEKIDVRNFIGMNYTPYDGDASFLEGPTEA
                     TNKLWGKLQALQKEERAKGGVLDMETEVVTSLTAYGPGYIDEETKDLEKVVGLQTDKPL
                     KRAFMPYGGIKMAEQACETYGYKVSDKIKDVFHNYEFKTHNQGVFDIYTPEMKVARHNK
                     ILTGLPDTYGRGRIVGDYRRVALYGIDALIEGKQKDFAACDRQGMRRYDFQLREEIADQ
                     IRALKGMKVMAESYGYDISKPAKDAREAFQWLYFGYLAAIKTQNGAAMSVGRISTFLDI
                     YIERDLQNGTLTEKEAQELVDHMVMKFRMVKFARIPSYNQLFSGDPVWATLEVAGMGQD
                     GRSMVTKNDYRFLHTLEDMGPAPEPNLTVLYSSRLPENFKKYAANISVTTSSVQYENDD
                     VMRPVWGDDYSICCCVSATETGKEMQFFGARANLAKCLLYAINGGVDEKTKQQVGPNYQ
                     PITSEYLDYDEVIAKYDKMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTKVERSF
                     ATGIAGFSHVVDSLSAIKYAKVKAIRDEDGITTDFQVEGDFPRYGNDDDRADEIATTLL
                     STFLEKLKHIHTYRDSKPTTSILTITSNVVYGKATGSLPDGRKAGEPLAPGANPSYGAE
                     QNGLLASLNSVAKLDYEDALDGISNTQTINPDALGHSDDERSENLVHVLDGYFDQGAHH
                     LNVNVFGKEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5746..6486
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 84; E-value:
                     3.9e-26)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_4"
                     /sec_met_domain="Radical_SAM (E-value: 2.6e-28, bitscore:
                     90.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNKQIKGYVHSLESFGSVDGPGVRYVIFLSGCAMRCQFCHNPDT
                     WKMKQGELYTADELLKKALRYKGYWGSKGGITVSGGEPLLQMDFLTEFFKKAKAEGVHT
                     NLDTSGNPFTDQEPWHSGWLELMKYTDLVMLDIKQIDEQEHIKLTGHSNKNILAMAREL
                     SDMKKPVWIRHVLVPGGSDKDEYLHRLADFIHTLSNVERVEVLPYHTLGKFKWENLGLS
                     YPLEGVNPPTQERIDNARKILGAI"
     CDS             6947..9460
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AstE_AspA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_5"
                     /sec_met_domain="AstE_AspA (E-value: 3.4e-32, bitscore:
                     102.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDLLSEIESYWTTRAEGYSEVNHKELNGMQKGAWLEVLKGQFPE
                     KAKDEIKILDIGTGPGFFPVILAEAGYKVTAVDYTQEMLDTAKRNAGNLCERISFYKMD
                     AQNLEFEDDVFDVVISRNLTWNLKDPKRAYEEWCRVLKPGGKLLNFDANWYGYLYDEEK
                     RLSYEEDRKSVESEHLDDHYLCTDIDRMEKIALQMPLSSINRPSWDRKFLKENGFESVA
                     VDTGIWQRVWSQEEKLNYHSTPMFMISAVKEEKNVWSENDGMGDSDGGYDRKRDLEDAM
                     LCAAPGMKKSGFLRLGGGEFSLPYTVICGSHPGKTVLITAAVHGGEYVGIQAAVELADK
                     LKPEKIHGRVILVKTVCRKEFEERSGSVCLEDEKNLNRVFPGNPNGTRMDRLAYEVVQK
                     LHSAADYYIDLHSGDDYEQLTPYIYYAGCADEDVVQMSRKMAEQADVPYMVKSNVASGG
                     SYNYAAACGIPSVLIERGQMGGWSPEEVHSTRKDVRNILCALGVYDGMRSYSNYYPMEI
                     EDVRYQSASVSGLWYPAKKPGDIIKVGEYLGCVKDYEGNILETSLSDLNGVVLYQAGSL
                     QVIKDGPMIAYGSFSRRKDERKEKITNYWAKRSDSFMEQRRAELHSDMADKWLKEIGTF
                     LPDGKLRILDVGCGAGFFSILLAKLGHEVTGIDLTPDMIIHSRELAKEENASCTFEVMD
                     AENPDFPDGTFDVIVSRNLTWTLPDAARAYKEWIRVLKMGGILINADANYGADDFSDTA
                     DLPANHAHFTVGDAMMQECEEIKRQLPISSYVRPAWDLETLGKLGINRFSIDLGISSRI
                     YTKKDEFYNPTPMFLICGEKNKCNN"
     CDS             9655..10491
                     /locus_tag="ctg32_6"
                     /transl_table=11
                     /translation="MKVQKKESKQSGNPARSLILVTVCTCTAIAFAAGGRIADFNGKNK
                     VYAASENRGKTFSSDADETDVLPTGIAGVVSGMNDTASPKKSVTRIGTSCEQVMVGQRI
                     KVIEDNMAEFDVSSSMESSINELDARTAALAESARMMSDEDYDTLLHIVEAEAGTEDVK
                     GRILVANVIMNRIKNKEFPDTVTEVVWQNTNGVPQFSPTYDGRINEVTVTDETREAVRQ
                     ALEGVDYSEGALFFIQKSEAESQNVSWFEKDLKRLFKYGVHEFYTYPDSAESSTGS"
     CDS             10927..12417
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_7"
                     /sec_met_domain="PALP (E-value: 2.1e-17, bitscore: 54.7,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVLYKSTRGKEETVTASMAILKGLSEDGGLFVPTEIPKLDVPMD
                     ELAKMSYQETAYEVMKCFLTDFTEEELKNCINNAYDEKFDTKEIAPLHEADGAYFLELY
                     HGATIAFKDMALSILPHLMTTAAKKNQVKNEIVILTATSGDTGKAAMAGFADVPGTKII
                     VFYPKHGVSPIQEKQMVTQKGNNTYVVGITGNFDDAQTAVKKMFNDKELEAELDAAGYQ
                     FSSANSINIGRLVPQIVYYVYAYASLVRQGKIKDGQEINVVVPTGNFGNILAAYYAKQM
                     GLPVHKLICASNDNKVLYDFFRTGTYDRKRDFILTTSPSMDILISSNLERLIYRIAGGD
                     AKKCAELMQSLTAGGEYTITEDMKAQLADFYGNYCTEDETAKTIAEIFKDSHYVIDTHT
                     AVAAGVYDKYVKDTNDTTPTVIASTASPYKFTRSVMEALGADTDGKDDFALADELSALS
                     GVKLPQAVETIRTAPVLHNRVVDAPDMPKAVKDILGIR"
     CDS             12738..12971
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="MSGRHYAAEDRRSVEDTHLAMARRQWEGNGISGTVKMSRREALFY
                     YLLDLILFYDTGGWKQWVFLKESSVYYRLGKQ"
     CDS             12920..13981
                     /locus_tag="ctg32_9"
                     /transl_table=11
                     /translation="MGVSERKFGVLQTGETVKIFHLENKSGAYAEVTDFGAILVKVCVP
                     DKDGTLTDVVLGYDDLASYEVNGCFFGSTIGRNGNRIGGAKFSVNGKEVVLAQNENDNN
                     LHSGPDGFEKKLWKVAEISDDKNSVIFNRISPDGENGFPGEFDVSVKYEFTEDNELRIH
                     YQGICDEPTVANMTNHSYFNLNGEGSGTAMDQYLTIHAKYYTPVADSHSIPTGVYEEVA
                     GTPMDFRTAKQIGQDIEAEFEQLKFTGGYDHNYVTDNYAKGNRRLIATAYSDKTGIAMD
                     VTSDCPCVQFYAANFVENEHGKNGHTYNKRDAFCLETQVEPNAVNVEDFHSPILNAGEQ
                     YDSVTAYHFYIRK"
     CDS             14213..15109
                     /locus_tag="ctg32_10"
                     /transl_table=11
                     /translation="MKKKNKTRSVTGLLFGFMERVSGDHVGAYATQAAYFLIMSFIPCI
                     LFLTTLVRYTPLTYNVVRDAIVAFIPENLQSFVLGIVVDVYKRSTAIVPLSAIVALWSA
                     GKGMQSIINGLNTIYHVKETRNWLLTRIYAVFYTLSLVIAVIVSLLMLVLGNEIQKAVS
                     RYIPFLGRVLGKILGARALLVFGVLFLVFLMLYKVLPNRKATFKSQIPGALIIAVAWSI
                     FSYGFSFYFEIFPGFSNMYGNLATIIMVMVWLYICMNLLLYGAEINAYFEKEFRIAHKS
                     VQELLAHEKEKKQQENE"
     CDS             15372..16250
                     /locus_tag="ctg32_11"
                     /transl_table=11
                     /translation="MIVVYLIFLAVIQAVTEFLPVSSLGHLCILEQYMGIGHETGLLSE
                     TMLHLGSAAAIIFLFRKDLKKIGLGLLGMFMDMIGNLNLYIHNKKTGESLGYARIVTGT
                     YRKTGALLVISMIPTALLGLTGKRLALLAADSQIVPGIGFLLTGVFLLVTDLNKSGGKK
                     GPREASYDSAMWIGICQGLAVFPGISRMGFTLCAALLCGYNRKFAVRFSVFMSLPAIIG
                     AFFTEIGNFGASEMTAGLGFTYVFAMIIAGFAGCLVIRNTIAMTQNVKLRYFAYYSFIV
                     GIITLALNFAL"
ORIGIN
        1 agtgccgcca ggctgcagga ctgcaacggt gcttttaccc tttgaaacat caatacctac
       61 tgcgttgtac attctacgta cctccaaaag tgaatttgca tggattccag catttctcat
      121 tgcctattca atctcctggg gtatcaaacg aacgtgaagt agtagttcaa cctgcataaa
      181 tcgaacggct gcaatgacag gctggctgac aggctttcgt acggacgcca atggtcctag
      241 gaggtgtcgt cagaccgatg cctaatcatt atacagctta aacaatgaga ggattaagtc
      301 ccaactggct gttgggtact gaaaccctac acttatatat taggaggagg gaagaatgtg
      361 gaagatgcgg aattgagaaa tatccttttt tctatacagg gaagcattgc cggttttcaa
      421 aatgatatgt ccgatgtaaa gaacgatatc gcagatatga agacagatat tgcaaacatg
      481 aagacggata tcacgaacat gaaggcagat atcacgaaca tgaaatcaga tattgtgcaa
      541 ctcaagggaa gcgtaaaaac tatagaactc aaactggaaa atgaaattga cagaaaaata
      601 tctgccctat ttgatgcacg tatggatgag cttcgctata gaaaggagaa taaggaaact
      661 cgagagaaag tttttgaact ggatatgcgt gtagacaatt tggaaaaagc catcatgcca
      721 gcgtaactgt aacagatgat tgtaaggctt gtacatagga taaacaggaa gaaattttat
      781 aacataaaaa agtacatgaa atttcttcct gctaaatttg tataattttt gtaaattttt
      841 caaaaaacag ttgaaatcac agaaataatt tgttatacta acttgcgtta cggggtatgg
      901 cgtagcttgg tagcgcgcac ggctgggggc cgtgaggtcg caggttcaaa tcctgttgcc
      961 ccgactgaca tatggttaaa tcgtttgtag tatatttaca atgaatgatt cagacgtatg
     1021 ttcattttaa aaaagccaaa taaagttata agtaaaatgc aatgataagg aatagtacac
     1081 ccggaccgga gcacagagaa ctgctggttg ctgagaagca gtggaaggaa attgtggaac
     1141 tcgcctttga gcagctgcct gaaattatac aagagtaggt gcagacggtt tccaccgtta
     1201 tatggagagg atataagaat accggatatc cggagattcc gtatcccatg agtgtatgac
     1261 attgttcata aataagagtg gtaccgcgta agatgataat atctttcgtc tcttgcagat
     1321 aagtctgtgg agatggaaga tttttttatg tctttttaca gtcaatcccc acagtccaaa
     1381 cataatattt acataacgga ggaagaaaaa atgatgaatc caagcaaata tcagagacag
     1441 tattttatgc cgcctgttaa atgcatgaaa tgggcagaaa aagaatatgt ggacaaagca
     1501 cctgtctggt gttctgtaga ccttcgtgac ggtaatcagg cactggtgat tccgatgagt
     1561 ctggaacaga aaattgaatt ctttaaactt cttgtaaaaa tcggtttcaa agaaattgaa
     1621 gtaggtttcc cggctgcttc tgaaacagaa tatgaatttc tgcgtaccct gatcgagcag
     1681 aatttgattc cacaggatgt aactattcag gttctgactc aagccagaga gcatatcatc
     1741 cgcaaaactt ttgaagctgt caaaggcgca ccaaaggcaa ttgtacatgt gtacaattcc
     1801 acttctgtag ctcagagaga acaggtgttt aagaaatcca aagaagaaat cttaaagatt
     1861 gcagtggatg gtgccgcatt attaaagaaa ctggctgatg aaacagaagg aaatttccag
     1921 tttgagtaca gccctgaaag ctttacaggc acagaaccgg aatacgctct ggaagtatgc
     1981 aatgcagttc ttgatgtatg gcagcctaca gcagataaca aatgcatcat caatctgcct
     2041 gtaactgtac agcattccat gccgcatgta tatgcaagcc aggtagaata tatgtgtgaa
     2101 aatctgaaat accgcgagaa tgtaatcgta tctctccatc cgcacaatga cagaggatgc
     2161 ggtgttgcag attctgaaat gggattactt gcaggtgcag acagaatcga gggtactctg
     2221 ttcggaaacg gtgagcgtac cggaaatgta gatattgtta cacttggtat gaatatgtat
     2281 tctcagggtg tagatccaaa acttgacttc tctgatatgc cgcatatttg tgaaatatat
     2341 gaagaatgta ccggaatgaa agtaggcgaa agaagtccgt acagtggtgc acttgtattt
     2401 gccgcatttt ccggctctca tcaggatgca attgccaagg gtatgcactg gagagatgac
     2461 aaggatccgg atcactggaa tgttccgtat cttccgatcg atccgacaga tgtgggaaga
     2521 aattatgacg cagatgttat ccgcatcaac agccagtctg gtaaaggtgg cgtgggatat
     2581 atccttgaga ccaaattcgg tcttaacctt cctccgaaaa tgcgtgaggc aatgggatat
     2641 gccacaaaag ctgtttcaga ccacaaacat aaagagcttc atcctgacga aattttcaat
     2701 ctgtttaaac agacctttga gaatatcaca gaaccgtaca gcatcaatga agtacatttc
     2761 cagcagaaag atggcggtat tgtaacaaaa gttacctcta ctttccgcgg aaagacaatc
     2821 actacagagg catccggtaa cggacgtctt gatgcagtca gcaatgcact gaagaaggca
     2881 tatgagctga aatattccct ggaaacatat caggagcatg cgctggagcg cagttcaagt
     2941 tccaaagcta ttgcttatgt cggtatcaaa aagccggatg gaacccttgc ctggggtgca
     3001 ggcgtagacg cggatatcat tcgcgcatct attgatgcac ttgtaacagc gatcaataac
     3061 cgttagattg ttccgacacg cccgattttt tcctgctgtt ttttgacttc tgcaggtcag
     3121 gctaatatcc gcttggcagg gaataatata gtttacataa aatatcaaaa atcagatacc
     3181 ggtcagattg tccagaggac ttcctgatcg gtattttttt gtatttataa aaatacaaga
     3241 aagtcttaat gtacgcgata aagtacaata aagaagcaaa ctccgatgaa aagctatcag
     3301 aattgtattt aattaaaatc ataaaggaaa ttaattgaca taacactcat gtttacgtat
     3361 actgacagcg tggacagaaa agtgtcctaa ataagtacaa tttacatttt attatctcac
     3421 tccaggccag tgagaaatgc gcggaaatat tttagagaaa gaggtaaaag aatgaaaaat
     3481 ttcgaacagt ggaatggctt taagggcaac cgttggaaag aaaaaatcga tgtacgtaac
     3541 tttattggaa tgaactatac accatatgac ggtgatgctt ctttcctgga aggacctaca
     3601 gaagctacaa acaaactgtg gggcaagctc caggcacttc agaaagaaga acgtgccaaa
     3661 ggcggagttc ttgatatgga gacagaggta gttacatctc tgacagcata tggtcccgga
     3721 tatattgatg aagaaacaaa agaccttgaa aaagttgttg gtcttcagac agataaacct
     3781 ctgaaacgtg ctttcatgcc atacggcggt atcaaaatgg cagagcaggc ttgtgaaact
     3841 tacggatata aagtaagtga caagattaaa gatgttttcc acaactatga atttaaaact
     3901 cacaaccagg gtgtatttga tatctacaca cctgagatga aagtagcacg tcacaacaag
     3961 atccttacag gtcttccgga tacttacgga cgtggacgta tcgttggcga ctacagacgt
     4021 gtggctctgt acggaatcga cgctctgatc gaaggaaaac agaaagactt cgcagcatgc
     4081 gaccgtcagg gtatgagacg ttatgacttc cagcttcgtg aagagatcgc tgatcagatc
     4141 cgtgctctga aaggcatgaa agttatggct gaatcttatg gatatgatat ctccaaaccg
     4201 gccaaagatg caagagaagc tttccagtgg ctgtacttcg gatatcttgc agccatcaaa
     4261 actcagaacg gtgctgcaat gagtgtcgga cgtatttcca cattccttga tatttatatt
     4321 gaaagagatc ttcagaacgg aactcttaca gagaaagaag ctcaggagct tgttgaccac
     4381 atggtaatga aattccgtat ggttaaattt gcacgtatcc cttcttacaa ccagttattc
     4441 tccggtgacc cggtatgggc aactctggaa gtagcaggta tgggacagga cggacgttcc
     4501 atggtaacaa agaacgacta tcgtttcctg cacacactgg aagatatggg accggctccg
     4561 gaaccaaacc ttacagtact ttattcttca agactgcctg agaacttcaa gaaatatgct
     4621 gcaaatattt ctgttacaac aagttctgtt cagtatgaga atgatgatgt tatgcgtccg
     4681 gtatggggcg atgactacag catctgctgc tgtgtatctg ctacagagac aggtaaagag
     4741 atgcagttct tcggcgctcg tgcaaacctt gcaaaatgcc ttctttatgc gatcaacggc
     4801 ggtgttgatg agaagacaaa acagcaggta ggaccaaact atcagccgat cacttctgaa
     4861 tatcttgact atgatgaagt aattgcaaaa tatgacaaaa tgatggactg gctggctcat
     4921 ctgtatgtcg gaacactgaa catgatccac tacatgcatg acaaatacta ctacgaagca
     4981 gcagagatgg ctctgatcga tacaaaggtt gagcgttctt tcgcaacagg tatcgcagga
     5041 ttctctcatg tagtagactc cctgtccgct atcaaatatg caaaagttaa agctatccgt
     5101 gatgaagacg gtattacaac agatttccag gttgagggtg acttcccacg ttatggtaat
     5161 gatgatgaca gagcagacga gattgcaaca actcttctgt ctacattcct tgagaaactg
     5221 aaacacatcc atacttaccg tgattccaag ccaaccacat ctatccttac tattacttcc
     5281 aacgttgttt atggtaaggc tacaggatct cttccggatg gaagaaaagc aggggaacct
     5341 cttgcacctg gcgcaaaccc atcttacggt gcagagcaga acggtcttct tgcttccctg
     5401 aactctgttg ccaagcttga ctatgaagat gctcttgacg gtatctccaa tactcagaca
     5461 atcaatcctg atgctctggg acacagtgat gacgagcgtt cagagaatct ggtacatgta
     5521 cttgacggat actttgatca gggtgctcat cacctcaatg taaacgtatt tggtaaagag
     5581 aaactgatcg acgctatgga acatccggaa aaagaagagt atgcaaactt cacaatccgt
     5641 gtatccggat atgctgttaa gttcatcgac cttacaagag agcagcagtt agacgttatt
     5701 gccagaacct gccacgacag aatgtaatta atggatgatg atataatgga taataaacag
     5761 ataaaaggct atgttcattc tttagaaagc ttcgggtccg ttgacggacc cggagtaaga
     5821 tatgtgattt ttttaagcgg ctgtgccatg agatgtcagt tctgtcataa tccggatacc
     5881 tggaagatga agcagggaga gctttatacg gcagatgagc ttcttaagaa agctttacgt
     5941 tataagggct actggggcag caaaggcggt atcactgtaa gcggtggtga gccattgctt
     6001 cagatggatt ttcttacaga attttttaag aaggcaaagg cagagggtgt gcatacgaat
     6061 cttgatacca gtggaaatcc cttcactgat caggaaccat ggcattccgg atggctggag
     6121 cttatgaagt atacagatct tgtaatgctt gatatcaagc agattgacga gcaggagcat
     6181 attaagctta ccggtcattc caataagaat attcttgcga tggcgcggga actttctgat
     6241 atgaaaaaac ctgtatggat ccgtcatgtg cttgtgccgg gcggaagtga taaggatgaa
     6301 tatctgcacc ggttagctga ttttatccat actctttcca atgtggagag agtggaggtg
     6361 ctcccttatc atacgcttgg taagtttaaa tgggagaatc tggggctttc ttatccactg
     6421 gagggggtta atcctccgac gcaggaaagg attgataatg cccggaagat tcttggagct
     6481 atctgagtaa aaatatatag ctgtcatatc ctctttttgg gggtgtggca gctttatttg
     6541 tttaaaaaag gggacgcgaa gcaggcgtat agttgtaccg gatacggttt cggcatctaa
     6601 gagattctaa gccctcgaaa atccgctaaa agcatgagac gaaaagtccg gaattactcg
     6661 ctgtcgctca gacaagggac ttttcgtctc ataacgcaga tttccgagga ctaagaatct
     6721 ctaagatgcc tgcaaatgca tccggtacaa ctatacgcct gcttcgctgg ttttggttaa
     6781 gatataatac aaggtggagt gtgaattata agaaggactt tgtttatata aaaatgaatt
     6841 gagacgtgaa atatatcccc cgggagggct tgttgggggg agggtggatt tgatataatt
     6901 ttggtcatat atgattataa attgcatgca tggaggttgg cataaggtga aggatttatt
     6961 atcggagatt gagagttact ggactacccg ggctgagggg tattctgaag ttaatcataa
     7021 ggaattgaat gggatgcaga agggggcatg gcttgaggtg ttgaaagggc agttcccgga
     7081 gaaagcgaag gatgagatta agattttgga tatcggaaca ggacctggat tttttcctgt
     7141 tattctggct gaggcgggat ataaggtgac tgctgttgat tatacacagg agatgttgga
     7201 tactgcgaag aggaatgccg gtaatctttg tgagcggatt tctttttata agatggatgc
     7261 tcagaatctg gaatttgagg atgatgtgtt tgatgttgtg atcagcagga atctgacatg
     7321 gaatctgaag gatcccaaga gagcttatga agagtggtgt cgtgtactga aacccggcgg
     7381 aaagcttctt aatttcgatg caaactggta cggttatctt tatgatgagg agaaacgcct
     7441 gtcttatgag gaagaccgaa agagtgtgga gagtgagcat ctggatgatc attatctctg
     7501 tacggatatt gacagaatgg agaagattgc actgcagatg cctctttctt ctattaacag
     7561 accgtcctgg gacaggaagt ttctgaagga gaacgggttt gaatctgttg cagtggatac
     7621 cgggatctgg cagcgggtgt ggagtcagga agagaagctg aattatcatt ctacgccgat
     7681 gtttatgatc agcgctgtga aggaagagaa aaacgtctgg tccgagaatg atggaatggg
     7741 tgattctgat ggcggatatg acaggaaaag agatttggag gatgccatgc tgtgtgctgc
     7801 tccgggtatg aaaaagagtg gatttctgag actgggcgga ggtgagtttt cgcttcctta
     7861 tacagtaatc tgcggttctc atcccggaaa gacagttctg atcaccgctg cggtccacgg
     7921 aggagaatat gtgggaatcc aggctgctgt tgagcttgcg gataagctga aaccggagaa
     7981 gatccatgga agagtgattt tggtcaagac tgtgtgcagg aaggaatttg aggagaggag
     8041 cggcagtgtc tgcctggagg atgaaaagaa tctgaatcgt gtatttccgg gaaatccgaa
     8101 tggaaccagg atggaccgtc tggcatatga ggtggttcag aagcttcaca gtgcagcaga
     8161 ttattatatt gatcttcaca gcggggatga ttatgagcag cttacgcctt atatttacta
     8221 tgccggatgt gcagatgaag atgtggttca gatgtcaagg aagatggcag agcaggcaga
     8281 tgttccctat atggtaaagt ctaatgtggc atccggtggt tcttacaatt atgctgccgc
     8341 atgtggcatt cccagtgttc tgatcgaacg tggccagatg ggaggctgga gtccggagga
     8401 ggttcattct acaagaaaag atgtgcgtaa tattctgtgt gcgctgggtg tttacgatgg
     8461 catgagaagt tacagtaatt attatcccat ggaaattgaa gatgtgcgtt atcagtctgc
     8521 cagtgtatcc gggctgtggt atcctgccaa aaaaccggga gatatcatta aggttggaga
     8581 gtatcttggc tgtgttaagg attatgaggg aaatattctg gagacaagtt tatccgattt
     8641 aaatggagtg gttctatatc aggcgggaag tcttcaggtt attaaggatg gtccgatgat
     8701 cgcatatggc agtttcagca gaagaaagga tgaacgcaag gaaaagatca caaattactg
     8761 ggcgaaaaga agcgacagtt ttatggaaca gagaagagct gagcttcaca gtgatatggc
     8821 tgataaatgg ctgaaagaga tcgggacttt tcttcctgat ggaaaattaa ggatcctgga
     8881 tgtgggatgc ggtgctggct tcttttccat tcttttagca aaactgggac atgaagttac
     8941 aggaatcgat ctgacaccgg atatgatcat tcattccagg gaactggcaa aagaagagaa
     9001 tgcctcctgt acgtttgaag taatggatgc ggaaaatccg gattttcctg atggtacctt
     9061 tgatgtgatc gtgtccagaa atcttacctg gacacttccg gatgcagcaa gagcatataa
     9121 agaatggatt cgtgtgctga aaatgggagg aatcctgatc aacgcagatg ccaattatgg
     9181 tgcagatgat ttctcagata ctgctgatct gcctgccaat catgctcatt ttacagtagg
     9241 cgatgccatg atgcaggaat gcgaggaaat taaacgccag cttcctatca gttcctatgt
     9301 acgccctgcc tgggatctgg agacactggg aaaactgggt atcaacagat tctccattga
     9361 tctgggtatc agcagcagaa tttatacaaa gaaagatgag ttttataatc caacccctat
     9421 gttcctgatc tgcggcgaaa aaaataaatg taataattga gaaaaatgaa gcatatatta
     9481 aagggagatt tcattgatgg aaccttcctt ttttcttttt tgcaagccaa aatgttacaa
     9541 aaatatgaaa aaagcttgac aaaatcaatt atattaaata taattttctt ataagttaca
     9601 gaaatgttac agccataaaa acctgtaatt aaaaaaactc aaggaatgat aagtatgaaa
     9661 gttcagaaaa aagagtcaaa acagtccggc aatccggcgc ggagtctgat actggttaca
     9721 gtgtgtacct gtacggcgat tgcgtttgca gcaggcggca gaatagcaga ttttaatgga
     9781 aaaaacaaag tatatgcagc ttctgaaaat agggggaaaa ctttttcctc tgatgctgac
     9841 gaaacagatg tattgccaac aggaattgca ggagtagtat ccggaatgaa tgatacagct
     9901 tctcccaaaa aatcagtcac acgtatcgga acttcctgtg aacaggtaat ggtcggtcag
     9961 agaatcaaag ttattgaaga taatatggca gaattcgatg tcagctcttc tatggagagc
    10021 agcatcaatg agttggatgc aaggacagcg gctcttgcag agagtgcccg gatgatgtcg
    10081 gatgaggact atgatacatt gcttcatatt gtagaagctg aagcaggtac tgaggatgtc
    10141 aagggacgta ttctggttgc caatgtgatc atgaaccgta taaagaataa ggaatttccc
    10201 gatacagtca cagaagtggt atggcagaat accaatggtg ttccgcagtt ttcaccgact
    10261 tatgacggac gtatcaatga agtaactgtt acagatgaga caagagaagc cgtcagacag
    10321 gctcttgaag gtgtggatta ttcagaagga gcactgtttt ttattcagaa atctgaagct
    10381 gaaagccaga atgtctcctg gtttgagaaa gatctgaaaa ggctgtttaa atacggcgta
    10441 catgaatttt atacctatcc ggattcagca gaaagttcca caggatcgta ataaacgata
    10501 ctcttcatat aactcattta acaggattgc ggtaatactg ctcaaaatat ggacatattc
    10561 ttcgggaaca aaagaatatg tccatatttt tgatttatag taatcgatca tagatactgt
    10621 tcactggaaa tatcccgcga ggtgtttttt gtgagcgaag gtcacagaaa aaccaagaca
    10681 tactgcgcga atttatgcga ttagcataaa ttctgtgcat cgcgaagcgt gttgctgtga
    10741 acagagtgaa cagtaatcaa tcataaaaag atagaaaaag agaaataatt taggatagta
    10801 ttttgctaaa gtatatgcta taatgtgctc aattggcgaa atgaataact gtaactgttc
    10861 agcggtttat tattactgcc aatatactga acagttacga ataactttgg aaaggcagga
    10921 aatatcatgc aggtattata caaaagcaca agaggaaaag aagaaaccgt aacagcttct
    10981 atggctattt taaaggggct ttctgaggat ggcggcttat ttgtgccgac agagattccg
    11041 aagctggatg tcccaatgga tgagctggca aagatgagct atcaggagac agcatatgaa
    11101 gtaatgaaat gtttccttac tgattttaca gaagaagaat taaagaactg catcaacaat
    11161 gcctatgatg aaaaatttga tacaaaagag attgcaccgc ttcatgaagc agacggagct
    11221 tatttccttg agctgtatca tggtgcgacc attgcgttta aggatatggc attatcaatt
    11281 cttccacatc ttatgactac agctgctaag aagaatcagg taaaaaatga gattgttatt
    11341 cttaccgcta cttccggaga tacaggtaaa gcggcaatgg ccggatttgc agatgttccg
    11401 ggaaccaaga tcatcgtttt ctatccgaaa catggtgtaa gtcctatcca ggagaaacag
    11461 atggtaactc agaaaggcaa caatacatat gttgtgggaa ttaccggaaa ctttgacgat
    11521 gcacagactg ccgtaaagaa aatgttcaat gataaggaac tggaagcaga acttgatgct
    11581 gcaggatatc agttctcatc tgcgaactct atcaatatcg gacgtctggt accgcagatc
    11641 gtttattatg tatatgcata tgcatcactt gtacgtcagg gcaagatcaa agacggtcag
    11701 gagatcaatg tggtagtacc taccggaaac tttggaaata tcctggctgc ttattatgca
    11761 aaacagatgg gacttccggt tcacaaactt atctgtgcct ccaatgataa caaggttctg
    11821 tatgatttct tccgtacagg aacttatgac agaaagcgtg actttatcct tacaacctca
    11881 ccgtccatgg atattctgat ctccagcaat ctggaacgtc tgatctaccg tatcgcaggc
    11941 ggtgatgcaa aaaaatgtgc agagctgatg cagtctctta ctgcaggcgg cgagtatacc
    12001 atcacagaag acatgaaggc acagcttgca gacttctatg gcaattactg tacagaagac
    12061 gaaacagcaa aaacaatcgc agaaatcttc aaagacagtc attatgtgat agatacccat
    12121 actgcagttg cagcaggtgt ttatgacaaa tatgtaaaag ataccaatga taccacacca
    12181 actgtcattg catccacagc aagcccatat aaatttacaa gaagtgtaat ggaagcactt
    12241 ggagcagata cagacggtaa ggatgatttt gcattggctg atgaactgag tgcgctttcc
    12301 ggagtgaaac ttccacaggc agttgagacg atccgcacag caccggtgct tcataaccgg
    12361 gtggtagatg cgccggatat gccaaaggca gtaaaagata tccttggaat ccgataatcg
    12421 ttactgttca ctccgttcac agtaacgtag ccaaaattca ttccagattg cctgcggcaa
    12481 tggaattttg gcttgtatgt ctcgggattt tggcatattc atgccaaaac acctcgcggg
    12541 atagtggtgt gtgaacatta accgataatc tccatattat aaaaaatata attaattcta
    12601 cattttatgt tgaaaaagaa catatactgg agtataataa aaatcagtta aaaacagtga
    12661 atatcctgaa atgtacgagg ccccttcttt ttttgaacct acatcgactt taacgggaac
    12721 ccaacatcgc aggccggatg tcaggccgtc attatgcagc ggaagacaga aggtctgttg
    12781 aggataccca cctagctatg gctaggcgtc aatgggaagg gaacggcatt tcgggaactg
    12841 taaaaatgag ccgtagagag gctctttttt attatctttt ggatttaata ttattttatg
    12901 atacgggagg ttggaaacaa tgggtgtttc tgaaagaaag ttcggtgtat tacagactgg
    12961 ggaaacagta aaaatttttc atctggaaaa caaatccggg gcatatgcgg aagtgacaga
    13021 ttttggagca atcctggtta aggtctgcgt acctgataaa gatggtactt taacagacgt
    13081 agtacttgga tatgatgatc tggcatctta tgaagtaaat ggatgctttt tcggttcaac
    13141 catcggcaga aacggaaacc gcatcggcgg tgcgaaattc tctgtcaatg gcaaagaagt
    13201 agttcttgct cagaatgaga atgacaataa tcttcacagc ggtcctgacg gatttgaaaa
    13261 aaagctctgg aaagtggctg agatttccga tgataaaaac agtgttatat ttaaccgtat
    13321 aagtccggat ggcgagaatg gtttcccggg agaatttgat gtgtctgtaa aatatgagtt
    13381 tacggaagac aacgaactga ggatccatta tcagggaatc tgcgatgagc cgacagttgc
    13441 caatatgaca aatcattctt atttcaatct gaatggtgag ggaagcggaa ccgccatgga
    13501 tcagtatctt acaatccatg caaaatatta tacacctgta gccgacagtc attccattcc
    13561 tacaggagtg tatgaggaag ttgcagggac tcccatggat ttcagaactg ccaaacagat
    13621 cgggcaggat attgaagcag aatttgagca gctgaaattc acaggcggat atgaccacaa
    13681 ttatgtgaca gacaattatg caaaaggaaa cagaagacta atcgcaaccg catacagtga
    13741 taaaaccgga attgccatgg atgtcacttc cgactgtcca tgtgtacagt tttacgcagc
    13801 aaattttgtc gaaaatgaac atggtaaaaa tggtcatact tacaataagc gggatgcttt
    13861 ctgtctggaa acgcaggttg aaccgaatgc ggtcaatgtt gaagatttcc actccccgat
    13921 tcttaatgca ggtgaacagt atgattctgt gactgcttat catttctaca tcagaaagta
    13981 aaaatctgac cataaaacta attacatatt gatccggttt ttttcatatc tacagcgttc
    14041 cagcatgaaa agaaccggat tttattatcc ataattcatg tttgtcataa cggcagtttc
    14101 atggtatgat agtaaacaga gatattcgaa acagttatct ttataattac agcaatcacc
    14161 ataaatgcat tatctaaaat gactgctgta aaataacaga atggagacat atatgaaaaa
    14221 gaaaaataaa acccggtctg ttacagggct tttattcggg tttatggaac gtgtatccgg
    14281 agatcacgta ggagcttatg cgacacaggc agcgtatttt ctgatcatgt cttttattcc
    14341 ctgtattctg tttctgacta cactggtacg gtatacacct ctgacctata atgtagtcag
    14401 ggatgcgatt gttgctttta ttccggagaa tctgcagagt tttgttctgg gaatcgtggt
    14461 agatgtatac aaaagaagta ctgcaattgt ccctttgtca gcaattgtgg cactgtggtc
    14521 tgccggaaaa ggaatgcagt ctatcatcaa tggattaaat accatttatc acgtaaaaga
    14581 aacccgtaac tggctgttaa ccagaattta tgcagtattc tatactttat cactggtgat
    14641 tgcggtaatc gtgtctctgc ttatgcttgt actcggaaac gaaatacaga aagctgtatc
    14701 aagatatatt ccttttcttg gaagagttct gggaaaaata ctgggggcaa gagcactgtt
    14761 ggtatttggt gtgttgtttc tggtttttct tatgttgtat aaggttcttc cgaacagaaa
    14821 agccacattc aaaagccaga ttcccggagc cttgatcata gcagttgcat ggtcgatatt
    14881 ttcatacgga ttctcttttt attttgagat ttttccgggg ttcagtaata tgtacggaaa
    14941 ccttgcgacg atcatcatgg tcatggtgtg gttgtatatc tgtatgaatc ttctgttata
    15001 cggtgcagag atcaatgctt attttgaaaa agaattccgg attgcacata aatcggtaca
    15061 ggaactgctg gcacatgaaa aagaaaaaaa acagcaggaa aatgaatgaa atttggctgt
    15121 tactgttcac tggtaatatc ccgcgaggtg ttttttgtga gcgaaggtca cagaaaaccc
    15181 gagacatact gcgcgaattt atgcgattag cataaattct gtgcatcgcg aagcgtgttg
    15241 ctgggaacgg agtgaacagt aacttttggc tacgttgtga acatgacagt cagggggctt
    15301 tttattgtaa agcctttctg agtgtgctat aataaaccac aattttggag aaacaaaaag
    15361 gaatcagttc tatgatcgtt gtatatttga tatttttggc tgtcattcag gctgtgacgg
    15421 aatttcttcc tgtcagcagc ctgggacatt tatgcatatt ggaacaatat atgggaatcg
    15481 gtcacgaaac cggattgctg tcagaaacga tgctccatct tggaagtgcg gcagcaatta
    15541 tatttttgtt ccgcaaagat ttaaaaaaaa tcggactggg acttctgggg atgtttatgg
    15601 atatgatcgg taatctgaat ctatatatcc ataacaagaa gacaggggaa agtttgggct
    15661 atgccagaat agtcaccgga acatatcgga aaacaggtgc acttcttgtg atttccatga
    15721 tcccaacagc acttctggga cttacaggaa aacggctggc tcttctggcc gcggactctc
    15781 agattgttcc gggaatcgga tttttactta caggcgtatt tcttctggta acagatctga
    15841 ataaatccgg tggaaaaaag ggaccgagag aggcttctta tgacagcgcc atgtggattg
    15901 gaatttgtca ggggcttgct gtctttccgg ggatttccag aatgggattt acgttatgtg
    15961 ctgcactgtt atgcggatat aaccgcaaat ttgcggttcg tttttctgtt tttatgagtc
    16021 tgcctgctat cataggtgct ttttttacgg aaatcggaaa ttttggtgct tctgaaatga
    16081 cggcaggact tgggtttacc tatgtatttg caatgatcat cgccggtttt gcgggatgtc
    16141 ttgttatccg aaatacaata gccatgactc agaatgtaaa attacgctat tttgcatatt
    16201 attcatttat agtcggtatt attacactgg cattaaattt tgccctgtaa agggaagata
    16261 tttacgagaa gatcaaggag gggagcctta gaatggcagc atcaaagagt aagaataccg
    16321 ggcattcggg aagaaataca aaaaagaaga cagcaatgga acaggaagtc ggcagatttc
    16381 agacagaaat catattattt gtgattttgg ccgcatgtgt gatcctgatg gcaagcaatt
    16441 ttggagcagg tggttttgtg ggagatgcga tcagtaattt ctgttt
//
