LOCUS       c00104_gnlPro..        13528 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCPIDHJJ_104.
ACCESSION   c00104_gnlPro..
VERSION     c00104_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 16:48:00
            Original ID  :: gnl|Prokka|KCPIDHJJ_104
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13528
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..189
                     /locus_tag="ctg104_1"
                     /transl_table=11
                     /translation="GKRYAEPSKRKERGLYRDGNRTYNADAVGAYNILRKYHSVSGVKR
                     ELSVTGLKTPEIIKVAV"
     protocluster    1..13528
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[360:8607]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      361..8607
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13528
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13528
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(297..422)
                     /locus_tag="ctg104_2"
                     /transl_table=11
                     /translation="MPMTPNTEQDWKAWRNLMWSEILTESVKSYMDCKCLNAISI"
     CDS             complement(361..1878)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.3e-11, bitscore: 35.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.6e-11, bitscore: 33.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.4e-06, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLYSSKTEIRHKIFTEIARMAYEGQSPEMLEELPYKIVPGEIA
                     TYRDSIFLERAVVGERLRVAMGMSLRKVTEHAPISKGVEASVIEEKYYEPPLINVIKFA
                     CNSCPEKRVMITEGCQGCLEHPCVEVCPKKAVHMEGGRSHIDEDACIKCGKCLEACPYN
                     AIIKQERPCSKACGMNAIGSDEYGRAEIDQDKCVSCGQCLVSCPFSAIVDKGQIFQTIM
                     ALKSETPVYAIVAPAIAGQFPGMENNKIRGAFQALGFTDVREVAVGADLCTVEEAKDFL
                     EEVPEKLPFMATSCCPSWSMMAKKLFPEQAKCISMALTPMVLTARLIKQKEPDCKIVFV
                     GPCAAKKLEASRKSIRSYVDFVLTFEEVAGMFDAKGVDWKDIPEGEPLFHASADGRGFA
                     VSGGVAEAVVHAVKRIDPDREVKVMNAEGLQNCKKMLQMAKIGKYNGYLLEGMACPGGC
                     VAGAGTIQTVKKAAAALEKMKKEASFTDAYDSKYRARLESLEKFDVE"
     CDS             complement(2144..2908)
                     /locus_tag="ctg104_4"
                     /transl_table=11
                     /translation="MIFTKKYRTGQIVLTACIAAVCMFSDVHGAEVAGPPAPKSKSALT
                     QKPEATPIPASTPTPEQETETDKQNPADQGTLSKPDHPDTISADKLVFIGDSRTEGLRD
                     AVNDDSIWSCLSSMGYDWMVSTGVPQVEDQIEDNTAVIILMGVNDLYHVNDYISYINSK
                     AAEWGNRGAQTYFVSVGPVQNDPYCSNAEIESFNAAMQASLSGVTYIDVYSHLVSEGFS
                     TVDGTHYPDSVSVDIYNYILDHLEEQMSGIWG"
     CDS             complement(2886..3014)
                     /locus_tag="ctg104_5"
                     /transl_table=11
                     /translation="MAGYAAWDVSMLLFTATHSRELRYVKSNVSITAEGNDIYEKI"
     CDS             complement(2987..3241)
                     /locus_tag="ctg104_6"
                     /transl_table=11
                     /translation="MRLEKVQEALKTKKIHYEYTEENGCGSIDFMFRGLRFHIWEYEDR
                     VWGAETNVFEAGRSQDIEGDYEEIISGEILSWPDMLPGM"
     CDS             complement(3760..5400)
                     /locus_tag="ctg104_7"
                     /transl_table=11
                     /translation="MKGLLKFITCGSVDDGKSTLIGHILYDAKLLYADQEKALELDSKV
                     GSRGGAIDYSLLLDGLMAEREQGITIDVAYRYFTTDNRSFIVADTPGHEEYTRNMAVGA
                     SFADLAVILVDASQGVLVQTRRHARICALMGIRYFVFAVNKMDLIEYDEKRFRDIENQI
                     AALIEELKLANVTIIPVSATEGDNVTTKSDNMPWYKGEALLSHLETVDIKEDTEKGFYM
                     PVQRVCRPNHEFRGFQGQIENGAIRAGDLVTTLPSKEEAHVKSILVGDKEVQEAVQGQP
                     VTIQLDREVDVSRGCVLTIDSGAVLTDSVEADILWMDDNALTDGKNFFVKIGTKMIPGL
                     VTKINYSVDVNTGEKKSAYTLKKNEIASCTLEFSEKIVVDEFDRHRTLGELILIDRVTN
                     MTSACGVVRKTFVSQDRSQIGKVDEQVRAGLKGQTPVVVEFPIGKEGITLDFVEQVEKG
                     LTVLGKHTYLYHPAASENYAETVRHLKAAGLVVLLVLDENTAKDETLKTLDGFYANWQI
                     DGITVKDAIDFVKKKSAFTVQSVHDGNYI"
     CDS             complement(5402..6520)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAPS_reduct"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg104_8"
                     /sec_met_domain="PAPS_reduct (E-value: 2.6e-65, bitscore:
                     209.7, seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCLKNALRKMCVTICGRFCSDEGVVAGYDNRIRTKYTAKWGVQIA
                     GMIFQTRSSVFAQVRKDSEYKQTEEDNAMSNLSHLDALEAEAIYIMREVAAECEKPVML
                     YSIGKDSSVMLHLAMKAFYPEKPPFPFLHIDTTWKFHEMIEFRDRIAKKNGIDMLVYTN
                     EEGVKAGINPFDNGSAYTDIMKTQALKQALTKYGFTAAFGGGRRDEEKSRAKERIFSFR
                     NSAQAWDPKNQRPEMWKLYNTKIQKGESMRVFPISNWTEKDIWQYIQRENIEIVPLYFA
                     KERPVIYRDGNIIMVDDDRLKLRPGEKIENKKVRFRTLGCYPLTGGIESEADTLDEIID
                     ETLSAVSSERTSRVIDHEAAGSMERRKREGYF"
     CDS             complement(6551..6865)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg104_9"
                     /sec_met_domain="Fer4_9 (E-value: 2e-13, bitscore: 40.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.9e-09, bitscore: 26.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.9e-05, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRIQKSKCAGCGRCIEACPGNLIKKDKENKAFIRQVRDCWGCT
                     SCIKECRHDAIRFFLGADVGGRGASMVVSEKPDISTWTVEKPDGTKITIQVNKKDANKY
                     "
     CDS             complement(6862..8607)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 71.4; E-value:
                     2.7e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_10"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.4e-23, bitscore:
                     71.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-08,
                     bitscore: 25.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTERIRTDVLIIGGGTAGCFAAYVIGKKSGRKVLIAEKANIKRS
                     GCLAAGVNALNAYITEGRVPQDYVDYAKKDAHGIVREDLLLTMSERLNHVTKVMEDLGL
                     VILKDENGKYVARGNRNIKINGENMKPILAKAAAEQENVTVLNHVNITDYKTENKKVTG
                     AVGFSVNEDIFYDIDAKAVLCATGGAAGLYRPNNPGFSRHKMWYPPFNTGAGYAMGLLS
                     GAEMTTFEMRFIALRCKDTIAPTGTIAQGVGARQVNAHGDIYETKYGLTTSQRVYGTVM
                     ENREGNGPCYLRTEGISKEQEQDLYKAYLNMAPSQTLKWMEAGKGPSEENVEIEGTEPY
                     IVGGHTASGYWVDNNRATTIEGLYAAGDVAGGCPQKYVTGALAEGEIAAEAILEYLNGK
                     DDDRIAAENKEEALERGGEQELSQTAIAKKAEYESHLNASRSLMNAEQLEEAMQKIMDQ
                     YAGGIGTDYRYSGMSLAKADEKIAALLPVVDTLAATDTYELMQIYELRERLIVCQAVIA
                     HLAARKETRWHSFGENTDYPQQSEEWMKYVNSRMENGEIKIVYRDLITKENTGLNTAEK
                     GAGER"
     CDS             complement(8719..9777)
                     /locus_tag="ctg104_11"
                     /transl_table=11
                     /translation="MYVELKNINKTYGSYQASRNVNFGIEKGKLIGLLGPSGSGKTTIL
                     RMIAGLETPDSGEVIIDGKVVNDVPASQRGIGFVFQNYALFRYMTVYDNVAFGLKVQKA
                     DKKKIDARVRELIKLVGLEGLEKRYPSQLSGGQRQRVAFARALAPNPQVLLLDEPFAAI
                     DAKIRQELRSWLKEMIGKLGITSIFVTHDQDEAIEVADEIIITNAGRIEQKGTPIGVYR
                     NPETAFAASFFGQPSVLKDADDFHTFAQAEGADKIIVRPEFVKISKLDEVEKFKTSVSR
                     GVVERVSFRGDNLELQVRVNNSVVTARRSLEKADIREGETVNVFLYRIFALRGDSVQLI
                     ENEAVRDDFVII"
     CDS             complement(9779..10603)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 60.2; E-value: 7.1e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg104_12"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.7e-19, bitscore:
                     60.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNNEKTSEKITKCLLVGISVLFLAVMLLLPLITVITEALRSGWK
                     VYAAAVTDEYTIKALLLTVKATLFAVVFNTVFGVFAAWALTKFQFRGKKLLTTLIDLPV
                     TISPVIAGLIFLLIFGRQSPVYFFLMKLGMKVVFSVPGIIIATVFVTFPFISRELIPVL
                     EAEGSDEEEAAALMGAGGWTIFWKITFPHIKWALLYGVVLCTARAMGEFGAVSVLSGHL
                     RGKTNTLPLHVEILFNEFQYVPAFAVSSLLVIMAVIILVVRSLIEYKGKKEA"
     CDS             complement(10603..11439)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 82.9; E-value: 8.1e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg104_13"
                     /sec_met_domain="BPD_transp_1 (E-value: 2e-26, bitscore:
                     82.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNKSVIPGFGLSMGITISILSLVVLIPLASLVVYTAKLSFKD
                     FIETITRARVLASFYTSFVCAFAAAVINGIMGTVLAWVLVKYDFPGKRLMDGMIELPFA
                     LPTAVAGIALTSLTSDSGIVGSFFAGFGIKIAYTRIGITVAMIFVGIPFVVRSVQPVLE
                     KMDNSYSEAAGVLGAKKTTIFWKVIFPELKPAIFAGTGLAFGRCLGEYGSVVFIAGNKP
                     YYTEITPLVIMSELQEFDYSSATAIALVMLAVSFFILFLNSMIQQRNARILRGGNA"
     CDS             complement(11510..12508)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 56.3; E-value: 1.7e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg104_14"
                     /sec_met_domain="SBP_bac_1 (E-value: 4.2e-18, bitscore:
                     56.3, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKLFAFGLAVVLALMPVQAFGKTVSVTNVSYDPTREMFEQYNK
                     IFEDHWKEKTGEDVEVIQSHGGSGKQALEVANGLDADVVTLALEYDIESIENAGLIKAG
                     WKDKFDNDSSPYTSTIVFLVKKGNPRDIKDWDDLTKKGVGVVTPNPKTSGGARWNYMAA
                     WAYADKKYGGDEAQMKEFIKKLYRNVVVLDSGARGATTSFVENGQGDVLVAWENEAYLS
                     MRDYPDEYEIVTPSVSILAQPSVAVVDEVVDYRNTRDVATEYLNYLYSDEAQEIAAENY
                     FRPTNEKILKKHSDTFDLNINLANISDYGGWDKVQEKHFTDGGIFDQIYER"
     CDS             complement(12711..13199)
                     /locus_tag="ctg104_15"
                     /transl_table=11
                     /translation="MPKNKFQEVIFTIIMVFVMVYAMICYNIVLNTGTMTNETFLLAFH
                     ELTFMGPIAFILDFFIIGGLAKKIAFGIVDMRRDNPFHLVLAISAVSVAFMCPCMSFAA
                     TVLIKHAPASQIIPTWLQTTAMNFPMAFFWQIFYAGPFVRFIFGKLFPEKEKAAASAE"
ORIGIN
        1 gggaaaagat atgcagagcc gtccaaacgg aaagagagag ggttgtacag agatggaaac
       61 agaacctata acgcagatgc cgtaggcgca tataatatcc tgagaaaata tcactccgta
      121 tccggagtaa aaagagaact gtccgtaacc ggactgaaaa caccggaaat aataaaagta
      181 gctgtataac tctaaagagc aaacagtagt ggtgtcatgg atgcaccctg aaaaaaggcg
      241 gtatcccgcc ttaattcaga tgctctggta actcagttgc cgagtaattc actctgctat
      301 atactgattg cattcaaaca cttgcaatcc atataggatt tcactgattc agtcagaatc
      361 tcactccaca tcaaatttct ccaggctttc cagtcttgct ctgtatttgg agtcataggc
      421 atctgtaaac gaagcctctt tcttcatttt ttcgagagct gctgctgctt ttttaactgt
      481 ctggatagta ccggcacctg ctacacagcc gcccggacat gccattcctt ccaaaagata
      541 tccattatat ttaccaatct tggccatctg gagcatcttc ttacagttct gcagaccttc
      601 tgcattcatt acctttactt cccgatcagg atcaatacgc ttcaccgcat ggacaaccgc
      661 ttctgccaca ccaccgctga ctgcgaaacc tcttccgtca gcactggcat gaaacagtgg
      721 ttctccttcc ggaatatctt tccagtccac gcctttggca tcaaacattc ctgctacttc
      781 ctcgaaggtc agcacaaaat ccacatagct gcggatactc ttacggctgg cttccagctt
      841 cttggctgca cagggaccta cgaaaacgat cttacaatct ggttccttct gcttgatcag
      901 ccttgcagtg agaaccatag gtgtcagtgc catagagata catttcgcct gttccgggaa
      961 taatttctta gccatcatag accaggacgg acaacaggat gtagccatga aaggaagttt
     1021 ctcaggaact tcttccaaaa agtcctttgc ctcctccact gtgcacagat ctgcaccgac
     1081 ggcaacctct cttacatctg taaagccaag tgcctgaaat gctccccgta tcttattatt
     1141 ctccataccc ggaaactggc ctgcaatggc aggcgccacg attgcataca ccggtgtttc
     1201 actttttaat gccataatag tctggaaaat ctgtcctttg tctacaatag cactgaacgg
     1261 acaacttacc agacattgtc cgcaggatac acatttatcc tgatcaatct ctgctcttcc
     1321 atattcatca gagccaatag cattcatacc acatgccttt gaacatggac gttcctgttt
     1381 gatgattgca ttatacggac aggcttccag acactttccg catttgatac aggcatcttc
     1441 atcaatatgg gatctgccgc cttccatatg cactgctttc tttggacaga cttccacaca
     1501 gggatgctcc aggcacccct gacagccctc tgtgatcatt accctttttt cagggcagga
     1561 attacaggca aacttgatca cattgataag cggcggttca taatactttt cctcaataac
     1621 gctggcctcc acacctttgg aaattggcgc atgctctgta acctttctca gtgacatccc
     1681 cattgcaacg cgaagtctct caccaactac cgctctttcc agaaaaatac tgtcacgata
     1741 agtcgcaatt tcaccgggta cgatcttgta gggaagctct tccagcatct ccggagactg
     1801 gccttcatat gccatcctcg caatttctgt aaaaattttg tgtctgattt ctgttttgga
     1861 tgaatacagt cctctcattt tttcctcctg attttcgatt cggataactg tacggcaatc
     1921 caatgcaggg acaccgaaca atttccattt ataatttcat cactgctgca atcagcacac
     1981 tcatttttcc tcctgctgaa ctttcagcca cttcacagag aaacgaaatt ccgctcattt
     2041 ccgtttcctt atctgcatat catatcacca aatgcttcca ggctcaacac aacatcagaa
     2101 ttttcgctga attgtcgccc ccgaagttgc tgttcatatg ttgttatccc cagattccac
     2161 tcatctgttc ctccagatgg tccaagatat aattataaat atctacggac acactgtccg
     2221 gatagtgggt tccgtctacg gtggaaaatc cctcagatac cagatgggaa tatacgtcta
     2281 tgtaggtaac tccactcagg cttgcctgca ttgccgcgtt aaaactttca atctccgcat
     2341 tactgcaata gggatcattc tgcaccggac ctacagacac gaaataagtc tgcgctcctc
     2401 tgttccccca ttcagcagct ttggaattaa tataactgat gtagtcattg acatgataaa
     2461 gatcattaac acccatcagg ataataaccg ctgtattgtc ctcaatctga tcttctacct
     2521 gcggcactcc tgtagatacc atccagtcat atcccataga agaaagacag gaccaaatgc
     2581 tgtcatcgtt taccgcatcc ctcaatccct ctgttctgga atctccgata aataccagtt
     2641 tatctgcgga gatagtgtcc ggatggtctg gcttgcttaa agttccctgg tctgccggat
     2701 tctgtttatc tgtctcagtt tcctgctccg gtgttggagt agatgcaggt attggtgttg
     2761 cttcaggttt ttgtgtcagt gccgatttgg atttcggtgc cggcggacct gccacttctg
     2821 ccccatggac atctgaaaac atacagacag ctgcaataca tgcggttaat acgatttgtc
     2881 cggttctata ttttttcgta aatatcattc ccttctgcag taatacttac gttacttttc
     2941 acatatctca actccctgga gtgtgttgct gtgaacagta acatacttac atcccaggca
     3001 gcatatccgg ccatgagagg atttctccgg aaataatttc ctcgtaatct ccttcaatat
     3061 cctggcttct gcctgcttcg aacacgtttg tctccgctcc ccagacacga tcttcatatt
     3121 cccatatatg gaatctcaga ccgcgaaaca taaagtcgat gcttccgcat ccattttcct
     3181 ctgtatattc ataatgaatt ttctttgttt ttaacgcttc ctgtactttt tccaaacgca
     3241 taaaatacct cctgattatc tgtacagtac cttctgtaat ataatacaga taactttcac
     3301 tgtaaaaaaa tgttctcgtg tacacccatc aaaagtcaaa cagatattcg caatccgctt
     3361 cgctacacag ctctacatat gctcttaatc ctgacgccat tatacaaaac gaattatatc
     3421 atactctgct gcataatatg taatctgaat gccacttcac aattgcccat tctacattct
     3481 gatcgatatt cactcatctt tatttctgtc ttttcttcgt tggtatcgcc aggatgatga
     3541 ttgtagcaat tacaaacaaa gttccaagca tcatctcttt ttttggtttt gtttactttc
     3601 attgttcgtt tgcatatttc tgttatcttt cctgtctgta ttattatgga ttctgaatat
     3661 ttgaaaataa gtataatccg ctgtaacgac acttgtcaag aaaacaaaat accgcagaga
     3721 ctttctttgt ctctgcggcg atttatagcc ctgttataat cagatataat ttccatcatg
     3781 tacactctgc actgtaaatg cagatttctt tttcacgaaa tcaatcgcat ctttcacagt
     3841 gattccgtca atctgccagt tcgcatagaa accatccaga gtctttaatg tctcgtcttt
     3901 tgctgtattt tcatcaagaa caagaagtac gaccagacct gctgccttaa gatggcggac
     3961 agtttctgca tagttttcac tcgctgccgg atgatacaga taggtatgtt ttccaagtac
     4021 agtcagtccc ttttctacct gctctacaaa atcaagagtg attccttctt taccgatcgg
     4081 gaattccact actaccggtg tctgaccttt cagtcctgca cgaacctgct cgtccacttt
     4141 tccgatctgg gatctatcct gagaaacaaa ggtttttctc acaacaccgc atgcagaagt
     4201 catatttgtg acacgatcta tcaggatcag ctcacccagt gttctgtgcc tgtcaaattc
     4261 gtctacaacg atcttctctg agaattccag agtacaggaa gcaatctcat ttttctttaa
     4321 ggtatatgcg cttttctttt cacctgtatt aacatccaca gaataattga tctttgtaac
     4381 caggccgggg atcatctttg taccgatttt tacaaagaag ttcttgccat ccgtaagagc
     4441 attgtcatcc atccagagga tatctgcttc cacagagtct gtaagaactg cgccggaatc
     4501 aatggtaagt acacatccgc gggaaacatc tacttctctg tcaagctgga tggtaacagg
     4561 ctgtccctgt accgcttcct gaacttcttt atcgccaaca agaatactct ttacatgagc
     4621 ttcttcttta ctgggaagag tagtcacaag gtcgcctgcc ctgatggcac cattttcaat
     4681 ctgtccctgg aatccgcgaa actcatgatt tggtctgcag actctctgta caggcatata
     4741 gaagcccttc tctgtatctt ccttaatgtc tacggtttcc agatgggaaa gaagcgcctc
     4801 acctttatac catggcatat tgtcagattt ggttgtaacg ttatcacctt ctgtggcaga
     4861 taccggaata atagttacat tggcaagttt cagttcttct atcagtgctg cgatctgatt
     4921 ctcaatgtcg cggaaacgtt tttcatcata ttcaataaga tccattttgt ttactgcaaa
     4981 tacaaagtaa cggattccca tcaatgcgca gattcttgca tgacgtcttg tctgtaccag
     5041 tactccctgt gaagcatcca ccaggataac tgccagatct gcaaaggacg cacccactgc
     5101 catgtttctt gtatattctt catgtccggg tgtatctgca acaatgaagc ttctgttatc
     5161 tgttgtaaaa taacggtatg caacatcaat ggtaattccc tgttcacgct ctgccatcag
     5221 accgtccaga agaagagaat aatcaatggc accgcctctg cttcctactt tggaatccag
     5281 ctccagagct ttctcctgat ctgcatagag aagctttgca tcataaagaa tatgtccgat
     5341 cagagtggat tttccatcat ccacacttcc gcatgtaata aatttcaata atcctttcat
     5401 tctagaaata cccctctctc tttcttctct ccatgctgcc tgctgcctcg tggtcgatca
     5461 ccctgctggt acgttcagaa gaaacagcac ttaacgtctc atcaataatc tcatccagag
     5521 tatctgcttc agattcaata cctccagtaa gcggatagca cccaagagta cggaatctga
     5581 cttttttgtt ttcaatcttt tcacccggac ggagttttaa tctgtcatca tccaccataa
     5641 tgatatttcc gtctctgtag atgaccggtc tttctttcgc aaaatataac ggtacaattt
     5701 cgatattttc acgctgaatg tactgccaga tatccttttc tgtccagttg gaaattggga
     5761 atactcgcat actctctccc ttctggatct tagtgttata aagcttccac atctccggtc
     5821 tctggttttt cggatcccat gcctgagctg aattgcggaa agaaaagatt ctttcttttg
     5881 ctctggattt ctcctcgtca cggcggccgc ctccaaatgc cgctgtaaat ccatatttgg
     5941 tcagagcctg ttttaacgcc tgtgttttca tgatatctgt atatgcagaa ccattgtcaa
     6001 atgggttgat tcctgccttt acaccctctt cattggtgta aaccagcata tcaattccgt
     6061 ttttctttgc gattctgtcg cggaattcga tcatctcatg gaatttccat gtagtatcaa
     6121 tgtgaaggaa cgggaatgga ggtttctccg ggtaaaatgc cttcatcgcc agatggagca
     6181 taacggagct gtcctttcct atagaataga gcataaccgg cttttcacac tcggctgcta
     6241 cttctcgcat aatataaatc gcctctgcct caagcgcatc aagatgagat aagttactca
     6301 ttgcattatc ctcctctgtt tgtttatact cggaatcttt tcgtacttga gcaaatacac
     6361 tagagcgtgt ctgaaaaatc attcccgcaa tctgcacgcc ccactttgcg gtatattttg
     6421 tccgaattcg gttgtcgtag cccgctacga cgccctcatc cgaacaaaat ctcccacaaa
     6481 ttgtgacgca catcttgcgt aaagcatttt tcaaacacac tctaaagact ctgagaatac
     6541 atacttatgt ttaatattta ttagcgtctt tcttattaac ctgaatagtg atcttagtgc
     6601 catccggctt ctccactgtc catgtggaaa tatccggttt ctctgataca accatacttg
     6661 cacctctgcc tcccacatca gctccaagga aaaagcggat ggcatcatgc ctgcattcct
     6721 taatacagga agtacatccc cagcagtctc ttacctgacg gataaaggct ttgttctctt
     6781 tatccttttt gatcagattt ccgggacagg cttcgataca tctgccgcat cctgcacatt
     6841 tacttttctg aatccgaatg ctcatctctc acctgctcct ttctctgctg tattcaaacc
     6901 tgtattttcc tttgtgatca ggtcacgata tacgatctta atctcgccgt tttccatacg
     6961 ggagtttaca tatttcatcc actcttcgct ctgctgcggg tagtctgtat tctctccgaa
     7021 actatgccat ctggtttcct ttctggctgc caaatgtgcg atcactgcct gacacacgat
     7081 cagtcgttcg cgaagttcat aaatctgcat cagttcataa gtatctgttg ctgccagagt
     7141 gtcaactact ggcaacaatg ctgcgatctt ttcatctgcc tttgcaagac tcatcccgct
     7201 gtatctgtag tctgtaccga ttcctcctgc gtactgatcc atgatcttct gcatggcttc
     7261 ctcaagctgc tctgcattca tcaaagaacg ggaagcattc aaatgtgatt cgtattctgc
     7321 cttcttagct attgcagttt gagacagctc ctgttctccg ccacgctcta aagcctcttc
     7381 cttattttcc gctgcgatcc ggtcatcatc tttgccattc agatattcca aaatcgcctc
     7441 tgctgcgatc tcaccttctg ccagtgcgcc ggttacatat ttctgcggac atcctcctgc
     7501 tacgtctccg gctgcatata aaccttcaat agttgtagct ctgttattat ctacccagta
     7561 accgctggct gtatgtccgc ctacaatata tggttctgtg ccctcaatct ctacattctc
     7621 ttcggatggt ccttttccgg cttccatcca tttcagagtc tgggacggtg ccatattcag
     7681 gtaagcttta taaaggtcct gctcctgttc tttggaaatg ccttccgttc tgagataaca
     7741 tggaccgttt ccttctctgt tctccatgac tgtaccgtaa actcgctggg aagttgtcag
     7801 accatatttt gtttcataaa tatcaccatg tgcattgacc tgtctggccc caacaccctg
     7861 agcaatagtt cctgtaggag caatcgtgtc cttacatctc aatgcaatga aacgcatctc
     7921 aaaggttgtc atctccgcac cggaaagaag tcccattgca tatcctgcac ctgtgttaaa
     7981 cggaggatac cacatcttat gtctggaaaa tcccggatta ttcggtctgt aaagtcccgc
     8041 tgcaccacct gtggcacaaa gaactgcttt cgcatcaatg tcatagaaaa tatcctcatt
     8101 aacgctaaat ccaactgcgc ctgtgacttt tttgttttct gttttataat ctgtaatatt
     8161 tacatgattg agaaccgtaa cattctcctg ttcagctgcc gcctttgcaa ggattggctt
     8221 catattttcg ccattgatct tgatgtttcg gtttcctctg gcaacatatt ttccgttttc
     8281 gtccttcagg atgaccagcc ccagatcttc catcaccttt gtcacatgat tcagtctctc
     8341 tgacatggta agaagaaggt cttctcttac gattccatgg gcatcctttt tggcataatc
     8401 cacataatcc tgcggcactc tgccttctgt aatatatgcg ttcaatgcat tcacgcccgc
     8461 cgccagacat ccgcttcgct taatattcgc tttctctgcg atcagaactt ttctgccgct
     8521 ttttttgccg atcacatagg ctgcaaagca tcctgccgta ccgccaccga tgatcagcac
     8581 atctgtcctg attctctctg ttctcattct ctcttaccct ttcctccata ccagtgtgcc
     8641 aacaagttga tttcccgatc agtcttgcgt ctgaatttct tatttcttca ttgtcgtcag
     8701 tcgccgcagc caccgctgtc agataattac aaagtcatcc cttacagcct cattttcgat
     8761 cagctgtaca ctgtcacctc tcagtgcaaa aatcctgtaa aggaatacat tcacagtctc
     8821 accttcccgg atatctgctt tctccagact tcttctggca gttactacgg aattgttgac
     8881 tctcacctga agttccagat tatctcccct gaaagaaacc cgttcaacca ctccccggga
     8941 tacggaagtt ttgaacttct ccacctcatc cagtttggag atttttacaa attccgggcg
     9001 gacaatgatc ttgtctgctc cttctgcctg agcaaaggta tggaaatcat ccgcatcttt
     9061 caacacagat ggctgtccga agaaggacgc tgcaaaagct gtctcaggat ttctataaac
     9121 ccctatagga gttcctttct gttcgatccg tcctgcatta gtgataataa tctcatctgc
     9181 tacttcaatg gcctcatcct gatcatgagt aacgaaaata ctggtaattc ccagcttccc
     9241 gatcatctct tttaaccagc ttcgcagttc ctgacggatt tttgcatcaa tggctgcaaa
     9301 gggctcatcc agaagcagca cctggggatt tggagcaagg gctctggcaa atgccaccct
     9361 ttgcctctga ccgccggata actggcttgg atatcttttt tccagtcctt ccagccccac
     9421 cagtttgatc aactctctga ctctggcatc aattttcttc ttatcagcct tctgaacctt
     9481 caaaccaaat gcaacgttgt cataaactgt catatagcga aacaacgcat aattctgaaa
     9541 tacaaatcca atcccacgct gactggccgg aacatcattt accacttttc catcaataat
     9601 gacctctccg ctgtccgggg tttccagacc tgcgatcatt cgaagaatag ttgtttttcc
     9661 gcttccgctt ggtcccaaca gaccaatcag tttacctttc tcaattccga aattcacatt
     9721 ccttgatgcc tggtaagaac catatgtctt attgatattt tttaactcta catacatatc
     9781 aggcttcctt ctttccttta tattcaatca ggcttctgac taccagaatg ataaccgcca
     9841 tgatcacaag cagtgaagat acggcaaacg ccggaacata ctgaaactca ttaaacaaaa
     9901 tctctacatg aagaggaagt gtattggtct ttcctcttaa atgtccggaa agtacagata
     9961 ccgctccaaa ctctcccatt gctcttgccg tacagagcac aactccatac agtaatgccc
    10021 atttgatatg agggaatgtg atcttccaga aaatggtcca tccacctgct cccatcaggg
    10081 ctgccgcttc ctcctcatcg cttccttctg cttccagaac cggaatcagt tctctggaaa
    10141 taaaaggaaa ggttacaaat acagttgcaa taatgattcc cggtacagag aatacaactt
    10201 tcatccctaa cttcatgaga aaaaagtaaa caggactctg tcgtccgaaa atcagaagaa
    10261 agatcaaacc tgcaataaca ggggaaatag taaccggaag atcgatcagg gtagtgagaa
    10321 gctttttacc cctgaactga aacttcgtca gtgcccaggc tgcaaaaaca ccaaaaacag
    10381 tgttaaaaac aactgcaaag agtgttgcct tcactgtaag aagaagtgct ttgatggtgt
    10441 actcatctgt cactgcagct gcatagacct tccatccgct ccgcaatgct tctgtgatca
    10501 cagtgatcag aggaagaagg agcatgactg ccagaaacag aacactgatc ccgacaagca
    10561 gacattttgt aattttctcc gaagtctttt cattgttgtc catcaggcat ttcctcctct
    10621 taaaattctt gcatttctct gctgtatcat actgttaagg aacagaataa aaaatgaaac
    10681 tgccaacatc acaagtgcga ttgccgttgc acttgaataa tcaaattcct gaagctctga
    10741 cataataacc agcggtgtga tttctgtata atagggttta tttcctgcga taaatacaac
    10801 acttccatat tcacccagac atcttccgaa cgcaagtccg gtccctgcaa agattgcggg
    10861 cttcagttcc ggaaaaatga ccttccagaa gatagttgtt ttctttgctc ccaacactcc
    10921 tgctgcctcg ctgtaagaat tatccatctt ttccagaacc ggctgtacac ttcgcacaac
    10981 gaacggtatc cctacaaata tcatggccac tgtaatgccg attcttgtgt atgcaatctt
    11041 gataccgaat cctgcaaaaa agctgcctac aattccggaa tctgaggtca gggatgtcag
    11101 tgcaatacct gctaccgctg tgggaagagc aaagggaagt tcgatcatcc catccataag
    11161 tctcttgccc ggaaaatcat atttcacaag cacccacgca agaacagttc ccataattcc
    11221 atttattact gctgctgcaa aagcacatac aaaactggta taaaaggatg ccagcactct
    11281 ggctcttgtg atggtttcga taaaatcttt aaaactcagc ttcgctgtgt agaccaccag
    11341 acttgccagg ggaatcagaa ctaccagact caatatggaa atggtaattc ccatggagag
    11401 cccaaaccct ggaatcaccg atttatttct ttttttcata atcaattacc acctctcctg
    11461 tctcatatat tctgtctgtg cttatgctct tgcttcatct tgtcttcctt tatctctcat
    11521 aaatctgatc gaaaattccg ccatctgtga aatgtttctc ctgcacttta tcccatccgc
    11581 cataatcact gatatttgcc agatttatat tcagatcaaa cgtatcactg tgcttcttca
    11641 ggattttctc attagtgggg cggaaataat tctctgctgc gatctcctgt gcttcgtcgg
    11701 aatacaaata attcaaatac tcagttgcca catctcttgt atttctgtaa tccaccactt
    11761 catctaccac cgccacagaa ggctgtgcca gaatacttac gcttggagta acaatctcat
    11821 actcatccgg ataatcccgc atggatagat aagcttcatt ttcccacgca accagcacat
    11881 ctccttgtcc gttctccacg aaagaggtcg ttgcgcctct tgcgcctgag tcaagaacca
    11941 ccacattccg gtaaagtttc ttgataaatt ccttcatctg tgcttcatcg ccaccatact
    12001 ttttatctgc gtaagcccac gctgccatgt agttccatct ggcaccgccg gaggttttcg
    12061 gatttggtgt tactactccc actccttttt tcgtcagatc gtcccagtct ttgatatccc
    12121 tgggatttcc tttcttcacc agaaatacga tagtggatgt ataaggagaa ctgtcattgt
    12181 caaatttatc tttccatcct gccttgatca gccctgcgtt ttcaatagac tcaatatcat
    12241 attccagtgc cagggttacc acatctgcat ccagaccatt ggctacctca agtgcctgtt
    12301 tccctgaacc gccatgggac tgtatcactt ccacatcttc ccccgtcttc tccttccagt
    12361 ggtcttcaaa tattttatta tactgttcaa acatctctct ggtaggatca taggaaacat
    12421 tggtgacaga caccgttttt ccaaaagcct gtaccggcat cagggccagt acaactgcaa
    12481 gaccaaaggc aaataatttt ctgatcatgt ttcatctcct ttaaagtacc agtagttttt
    12541 tgcattctct acttttcata gttattcgat atgttttata tgatattaca agaaatgaca
    12601 gaatttgtca atagtgtatt aaaataagta caatttatgt tgtgtagata agaacacaaa
    12661 aaaagcagca tcctgaaata cagaatgctg cagtcaaaat tacatatttt ttattcggca
    12721 gaagctgctg ccttttcttt ctccgggaaa agctttccga aaataaatct tacgaatggt
    12781 ccggcataaa agatctgcca gaagaatgcc atcgggaagt tcattgctgt tgtctggagc
    12841 catgtgggaa tgatctgact tgccggtgca tgtttgatca gcacagttgc cgcaaagctc
    12901 atacatggac acataaatgc aacggatact gctgagattg caagtacaag gtggaacgga
    12961 ttatctcttc tcatatccac aataccaaat gcaatcttct ttgcaagacc accgatgata
    13021 aagaaatcaa gaataaatgc aatcggtccc ataaatgtta attcatgaaa agctaacaga
    13081 aatgtctcat ttgtcattgt ccctgtgttc agtacaatgt tgtagcagat catggcataa
    13141 accattacaa acaccatgat aattgtaaaa ataacttcct gaaacttgtt tttaggcata
    13201 aaaaatcctc cttagatagt atgaataaca tcaattagag atttgtgttg ttcataacca
    13261 tccaggagga tgtaccgttt ccaataatac caaatatctg tttcttaaat ttaccgttgg
    13321 ttattatacg gactgtttta aaaaaagtca aggatttttt cagtacctgc agtgtgaatc
    13381 aggaaacaaa ggttactgtt cacacaccac tgtcccgcga ggtgttttgg catgaatatg
    13441 ccaaaatccc gagacataca agccaaaatt ccattgccgc aggcaatctg gaatgaattt
    13501 tggctacgtt actgtgaacg gagtgaac
//
