LOCUS       c00075_gnlPro..        16452 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JINFJOLG_75.
ACCESSION   c00075_gnlPro..
VERSION     c00075_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 03:15:44
            Original ID  :: gnl|Prokka|JINFJOLG_75
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3802
            Orig. end    :: 20254
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16452
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[13802:17015]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13213
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..16452
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16452
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             1942..2469
                     /locus_tag="ctg75_6"
                     /transl_table=11
                     /translation="MAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIATHELAEY
                     AKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKGREKLPD
                     VDIYSLVQYHGA"
     CDS             complement(2613..3542)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_7"
                     /sec_met_domain="PALP (E-value: 6.7e-69, bitscore: 223.2,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPDDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEELVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(3558..4352)
                     /locus_tag="ctg75_8"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             complement(4483..5013)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_9"
                     /sec_met_domain="PLDc_2 (E-value: 4.3e-28, bitscore: 88.7,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LFPQDLIINITASDEAEGIIAGAKKYIYIQTPYLIPEESILEALI
                     IAANSGIDVRIMVPCMPDHPFVYRATEYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNI
                     SSVGSANQDFRSYTLNFEVNSFNYNPALTQELKKIFEKDLDKCTLLTNDYFAQQSSWLK
                     FKQYFSRLLSPIF"
     CDS             complement(4964..5131)
                     /locus_tag="ctg75_10"
                     /transl_table=11
                     /translation="MDWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQIVSSGP
                     DNQHYGIRRG"
     CDS             complement(5278..5844)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_11"
                     /sec_met_domain="PLDc_2 (E-value: 2.3e-09, bitscore: 28.1,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLTVLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQ
                     RDMLKEHDLLPEKERLPRVRMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKN
                     AKKSVSLELYTFYSNQLGHRVLKALEEAAANGAKVRVIYDTSGSRGTKPSFFDHLRAAK
                     LSHLFPLQKSTGLLPHDSITTYIEN"
     CDS             6139..6603
                     /locus_tag="ctg75_12"
                     /transl_table=11
                     /translation="MLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRNATVYNRHGVKV
                     GHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVNRIKKHSFVYDE
                     NGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVTNY"
     CDS             complement(6672..8945)
                     /locus_tag="ctg75_13"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSNLSDLPDKDVLALVGSATDKRNAGII
                     DIAIDEYLKENDIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             9074..9928
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     72.5; E-value: 6.7e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg75_14"
                     /sec_met_domain="LysR_substrate (E-value: 2.4e-28,
                     bitscore: 89.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.8e-23, bitscore: 72.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAKEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTGLRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKYSNWITHLQLVRRKDQKVTPLMKRIIDS
                     LSR"
     CDS             10001..10186
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_15"
                     /sec_met_domain="Amidinotransf (E-value: 2.1e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             10318..10728
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_16"
                     /sec_met_domain="Amidinotransf (E-value: 2.9e-28, bitscore:
                     89.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEMQNATPSLADLAENPDYPFYL
                     DPMPNVYFTRDQQATIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWCDRY
                     THGRLEGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             10958..11230
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_17"
                     /sec_met_domain="Amidinotransf (E-value: 8.6e-31, bitscore:
                     97.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLKNYLHLSEIDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVT
                     YDRNYVSNDLLRKHGILVHEIHSSELSRGRGGPRCMSCPLVREDL"
     CDS             11478..12086
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_18"
                     /sec_met_domain="OTCace (E-value: 2.1e-37, bitscore: 119.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.5e-24, bitscore:
                     77.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLTLAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHD"
     CDS             12135..12278
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_19"
                     /sec_met_domain="OTCace (E-value: 5.7e-11, bitscore: 33.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEVTDEVFNSQYAWQFTEAENRLHSIKAIMAATLGNLFIPSVDEG
                     SK"
     CDS             12281..12703
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_20"
                     /sec_met_domain="AA_kinase (E-value: 5e-13, bitscore: 39.9,
                     seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVAFGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKLIGPFYTFNEMQR"
     CDS             12872..13213
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_21"
                     /sec_met_domain="AA_kinase (E-value: 3.7e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             13230..13766
                     /locus_tag="ctg75_22"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNNGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             13887..15053
                     /locus_tag="ctg75_23"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLHEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLACMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             15069..15230
                     /locus_tag="ctg75_24"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             15233..15838
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_25"
                     /sec_met_domain="LysR_substrate (E-value: 1e-18, bitscore:
                     58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLAKKVY"
     CDS             15983..16450
                     /locus_tag="ctg75_26"
                     /transl_table=11
                     /translation="MDSLHSTMNQHIKGKHLSFEERVIIQLRLKDGYSLRAIARELNCS
                     PSTISYEVKRGTVELYHGKVKRYKATQGHDAYQAHRKNCGRKSDFLRKTQFMRYVHKHF
                     FKDGWSLDVCSNRATAVGAFSSRDVVCTKTLYKYVDQGLLDIHNYDLPEKLK"
ORIGIN
        1 agaagttgaa tacgctaaag aacatggcgt tgatactatt attacggatc accatacttt
       61 tcaagaaaat aagccagatg cttatgcaat tgttcactgt aattatcctg gtcaagaata
      121 tccttttgat gattattgtg gtgcaggtgt agcttataca atttgtcgtg agcttatgca
      181 ggatcctgta ccagaattgc tagatttagc aatgatcggt actattggtg acatggttaa
      241 agttactggt gaaggccata ttattgtaaa acgtgggtta gatgttctta atcaaaccga
      301 acgaccgggc ttaagagcgc ttatcaaaaa tgccggttta acgctagaaa cgattaatga
      361 gacagatgta ggctttaata ttgctcctag acttaatgct gttggacgtt tggctaatgc
      421 taatctggca gtagagcttt tgcttagtga tgatgatctt gaggcacaga agatcgcaga
      481 tcagattgaa gacttaaata ataagcgtaa agagctaact actgaggttt acgatcgctg
      541 catggaatta gttcgtgaaa atagttggca aaagcaaaat actttagttt tatatgatcc
      601 tgattttcat gaaggagttt tggggcttgt tgctaacaag atagtggaaa aactgcataa
      661 accaacaatt gttttaacta aaaacgatga aggggagatt aagggatcag gtcgttcact
      721 cagtggtttt aacttatttg atgctcttaa tccgttaaaa gaaagtctat tgaccaaatt
      781 tggaggtcat gattttgctt gtggtttatc catggaagaa gataaagtaa atgacctacg
      841 ggaaaagttt gaagccgatt ttcatgttga cggtggttta gagactaaag agtacgatat
      901 ggaattgcct atgcatgact tatcacctca aactttggct caaattaatc aagtgggacc
      961 atttggtact ggtgatccgc agccaatttt tagtatttcg gatccaacta ttacacactt
     1021 tttcaaaata ggaaaagata agaatcatgt taaattaata gctaataaaa aagacggcaa
     1081 tttagcaatt gtgggattta ataaggatta tttgaataat aatttgttac catttatttc
     1141 aaaaatcttt gttactctct ctttgaatac ttatcgcaaa caagtatctt tgcaaggcat
     1201 catggaagga atagcctttg catccccaaa attagctgtg ccaacatcag taattgattt
     1261 aagacaagag aaatttgtca tgggccttgc agatcgttat ttgctttttg acaaaaagaa
     1321 tattccaatt gttaagaata gccttcaaat tgatgatgat aaaattagct tggttaaaga
     1381 ttatgatcaa tcgggtgaaa cagtagcttt gcttgatgtg cctcgcaatc aagtggaatt
     1441 aaatgcagct ttaaaaaaag attatcaaca aatttattta tgctttttat tagatcagtt
     1501 acctgttgaa caaattccag caaagagtta tttcggaaaa gtgttaaagt atatttatgc
     1561 ccatccagca ttaaagcctg aagactatcg cactgtagca ccatatctag gtttggatta
     1621 tgatagtgta ttgtttattt tgcgagtatt ctttgaatta ggttttgtta aattagacga
     1681 tcaaaaatta gttggtgagt ctaatccaaa gaagcaacca ttgacagctt ctaaatattt
     1741 aatggcaacg agttcacaaa ttaaatttat taatcaacta agaacgatgc ctactcaaaa
     1801 attaattaca tatgttaata atttggtaaa aagatagata aatatcaaga tttcagtact
     1861 tttataacaa atctttggta aaatatacaa gtcaaaagtg tttgaataca aacgcacaga
     1921 attatggagg tttttcttct tatggcgatt gattttagta aatatattgc aagtgttaag
     1981 gactttccta ataagggaat tgtctttcgc gatattacac ctattttgca agatggtgaa
     2041 ttgtatcgta ttgctactca tgaattggca gaatatgcaa agagtagaaa ggcagatgta
     2101 atcgtaggtc ctgaagcacg tggctttatt gtaggctgtc ctgttgcaac tgagttaggc
     2161 ttaggttttg ttccagcaag aaagccacat aagttgccaa gagaagttga acgtgcttca
     2221 tatgacttgg aatacggttc aaatagcctt gaaatgcata aagatgcaat taagcctggc
     2281 caaagagttg ttctctgtga cgatttaatg gctactgcag gtactttaag agcttctaag
     2341 gaattaattg aaaatcttgg tggtaagctt gtaggtgctg cattttacat tgaattgcct
     2401 gatttaaagg gtagagaaaa gttgcctgat gttgatattt acagcttagt gcaatatcat
     2461 ggtgcttaaa taaattcaat attgatctaa ttagtaaagg tcattatact aaaagtgttg
     2521 taccaacatt gactggtgca caatcaacag aaataaaaat aatactccta aggaaatttt
     2581 acttaggagt atttgtttac agaaattaag ttttaagcat taaataatgc agttgaaagg
     2641 taacgatcac cgccgtctgg aactacagta accacagcat gtcccttgcc taacttttta
     2701 gcaatttcga ttgcaccatg gatgtttgca ccagctgaaa taccaggtaa gaagccttcg
     2761 tttttagcta cttcacgagc tgtagccatt gcttcatcag tagaaactgt aattatatca
     2821 tcgtagatat ccttatctaa attcttaggg atgaaacctg cggcaatacc ttggatacca
     2881 tgtttacctg tttttccatc ttttaagagt ggagattcag ttggctcaag tgcaaatatc
     2941 ttagtggatg gattttcacg cctaagtgca tgtccaattc ctgataaagt accaccagta
     3001 ccaacaccag caacaaaggc atcaacggat ttgccgatac cattcattgc ggcaataatt
     3061 tctggaccag tagttaattc atgaatatta ggattttctg tattttcaaa ttgcattggc
     3121 atgaagtagc ctttctcttt aactaattct tcggccttag caattgaacc cttcataccg
     3181 tctgcacctg gtgtcaaaat aagttcagca ccatagccct tcattaattt acgccgctca
     3241 acgctcatag tttctggcat aacaataata atgtgatagt ccttagctgc agcaaccatg
     3301 gctaaaccga taccggtatt gcctgaagta ggttctacaa ttgtgccacc tggctttagg
     3361 ttgccttcac gttcagcttt ttcgatcata gctaaagcaa ttctgtcttt aattgaacca
     3421 gctgggtttt caaattctaa ctttacatag acatctgccg cgtcgtcagg tacaacgcga
     3481 ttcaacttaa gtaatggagt gttgccgata agttctgtaa ctgaattata aattgtagac
     3541 ataatgtatg cctcgtttta tttatctaat aatactaatt tgcttttttt aacttgagtt
     3601 agccagttat tgaaaaatgt tttctgagta tctttccatt gaaacaatag atttgataat
     3661 gaataatttt ctggcttctt ataatgtcgc tctggatgtg cagcaatctc tctttcatat
     3721 tcttttttaa ggccttttcg gccatattcg atatgagaga aaataaaatt ttgctcaggc
     3781 ttttctaaag aagagaccat aaatagatgc ccattatcgt caactgaatt aatggttaat
     3841 cgtggatctt gcataatctg tgttttatcc atttcagcgt aacgagcatg tggagcgata
     3901 aatcctttgc tgagtccatt taataaagga tgtggttcga taattaaatg aggaaaaaca
     3961 ccaaagattt ttttcgataa aattcttttt tgaatattgt aaaaataatc taaagcggcc
     4021 attgcacccc agcaaaaata taattgctgc aacttgtatt tatctaatag ttggagcaaa
     4081 catcggactt cctcgatgta ggtaacttga tcaaaatcaa gatgatctaa aggtgcgccc
     4141 gtaatgataa agccatcaaa ctctttgatt tgattaagat ctaatggctg ggaagttttt
     4201 gcaacttcag gtgggacagg acgattttga taatgcatac gtggataaaa gaaagtcagg
     4261 tctgcatctg gcaaaacgcg tgcaaatctt tgttgagtat ctaacttatc gtgcattaaa
     4321 ttcaaaacgc ctatttttac tctattagcc aagttttatc ctccttactt tttaatagtt
     4381 atcattatta tataacttat aaaaaataag taaagaaata aaactgcatt tttaaaatac
     4441 aaagtaaaac ccccatcgga tagaccgata gagggctttt cattaaaaaa taggtgataa
     4501 taatcttgag aagtattgct taaattttaa ccatgatgat tgttgagcaa agtagtcatt
     4561 agttaaaagg gtacatttat ctaagtcctt ctcaaaaatt ttctttaatt cttgagttaa
     4621 agcagggttg tagttgaatg agtttacctc aaagtttaat gtatagcttc ggaaatcttg
     4681 attggcggaa ccaactgaag aaatattaga accgctaacc atagtttttg catgaataaa
     4741 accatcatta tatttgtata ctttaacgcc atgggctact aaatacttag catagtattc
     4801 tgtagcacga taaacaaatg gatgatcggg catgcaagga accataattc gaacatcaat
     4861 accgctgtta gcagcgataa ttaaggcttc aagaattgat tcttcgggaa ttaaataagg
     4921 cgtttgaata taaatgtatt ttttagctcc tgcaataatt ccctcagcct cgtctgatgc
     4981 cgtaatgttg attatcaggt cctgaggaaa caatttgcat agcgacattt ttattatcat
     5041 tgatatcttt tcgattgaca gtaaatggtt taagttcctt taattcaaat ttaggtaaat
     5101 ttgttcttct gattgacgtg ttccagtcca ttgcaaaccg gacctccatt agaattggtg
     5161 attgcccaat tacacgtaaa tgggtatccc gccaatgacc gaattttggt gatttattga
     5221 catattgatc tccaatatta aatccgccaa tatagccaat atggtggtca ataataacta
     5281 attttctatg taagtggtaa ttgagtcgtg gggtagtaaa ccagtgcttt tttgaagtgg
     5341 aaataaatgg ctgagcttcg ccgcccttaa atggtcaaaa aagcttggct tagtgcctct
     5401 tgatccagag gtatcataaa ttactcttac cttagcacca ttagctgcag cctcttccaa
     5461 ggcttttaaa acacgatgcc ctaattggtt agaataaaaa gtatataatt ctaagctgac
     5521 agattttttg gcatttttga tatcagtaat catttggtca aaaagttctg gtccagaaat
     5581 aaatactttg acctgattat caaaagttaa aatcgcatca tcgttgttaa gatttagttc
     5641 cgaaagcatt cttactcgtg gaagacgctc tttttcaggt agaagatcgt gctctttaag
     5701 catgtcgcgt tgctcagcta aataatgtct ttgtaccttt ttttgctctt cttgaatagc
     5761 aaagatttca tcatgtgaaa gctgacgacc aaagaaaaga tataggataa aaccgatacc
     5821 gggcagaacg gttaatacaa gcatctatgc ccaagttgca acaacgctgc ggcgacttct
     5881 aaagaccgtc catacagcaa acgcaatatt gataatccat aagacttcga tagtcctacg
     5941 gattatatcc caagttaaaa tcatgaatta agtagtgtta taaataattt tagcagaatt
     6001 aagcaaatag ttataaaaca gatgagtaaa aaatgcttcc aattcgataa tttttgataa
     6061 aataagggat ggagaatggt ataaacacta cgggggtgga ttatgatgag aaaacaaatt
     6121 atttctgctg caggtataat gttagcagtt attggattag gcgcagcaac tacacaaagc
     6181 gttgatgcag ttgttactaa tccagttaga caaggtaaga gattaaatct aactagaaat
     6241 gctactgttt ataatagaca tggtgttaaa gttggacatt taagaaaggg aaagctttac
     6301 aaagtacgtg ccataaaagt aattaatggt aatacttatg taaagattcg taaaaataga
     6361 tttgttaagg aagaagcctt cttgccatat atgaagacta ctgtaaaagt agttaataga
     6421 atcaaaaagc attcctttgt ttatgatgag aatggtgaaa aaatcccagg caaattttta
     6481 aagcgtggtg ctaaggttaa ctatttaggc cataaagaaa ttaatgaaaa accatttatc
     6541 aaaattgctg atggtgaata tgttaaggct ttgaatgcct tgactacagt tactaattat
     6601 taatcaaaaa aaacactctg aaaactacat tgtagtaatt tagttttcag agtgtttttg
     6661 ttttaagtta attatctgtt tttcattact ggttgataaa tcaaatcaat aataattgct
     6721 gcaattaatg caaccacaac ggtaattaat aagttttgcc aactaatttg agccattgct
     6781 aaaccgcata aagctaaaat aaaggttaat gcgacatcgg caatttgaac aatacctaca
     6841 agtttagatg gataatcttg ccagaagtat ttacgagttc tagtaattaa tacaattaac
     6901 attgcactta gaactaagta aacatagacc atggtagaga tagaattgtg actccagcca
     6961 tgcatgttga ggtagctgaa aaaagcgata ccgataactg tccaacctgc agcaagagag
     7021 aatgcgattt tggctaacct tgccatattc caattttctg gtttgtaagt aatatgggta
     7081 cggtcggtac caatcatcat ggtaaccatg ttattcatga ttgtgtaaat aaccatagca
     7141 tttaatgcca ttggaatata gttgaagaag agatagccga aggttaaaag catagttaat
     7201 tcggcggttc tggcgagctt agcaagtgac caagtagtca ttcgttgata tacacggtga
     7261 ccagcatcaa gaattttaac aatagagctt aagccatcat ctagaagcac catcttactt
     7321 gaacgcttgg caacatcggc agcgttagaa acagcaatac caacttcagc ttgctttaaa
     7381 gcaggagagt cgttaacacc atcaccagtc ataccaacga tataaccttt ttcttggaag
     7441 aatttaacca tcttaagttt atcttcaggt aaaacatcgg caattcctgc taattcatca
     7501 atatcggtgc tttcatcaaa gtcatgaata gagataacgt taccagttaa atcaacttgt
     7561 tcagcgactg ctgcggcagt tctttgatta tcaccagtta acatgattgg acgtacgccc
     7621 cgttttttaa gttctgctaa agcagcctta gagtcctttc ttactttatc ttgtaagata
     7681 aatactcccg caagtttgtc atcaattaac acggcaactg agcgtccagc tttaaaattg
     7741 atgccttcaa ctgcttcatt tgcattctta tcgattaatg aaagttgctt aaatgaacct
     7801 aacttaacat tgtgaccatc tacttcagcc atagaatagc cagtgtcaga agtaaatggg
     7861 gtaaagtgtt caacgtccat gacagggata tcgttttctt ttaagtattc atcaatggcg
     7921 atatcaatga tacctgcatt gcgcttatca gttgcactac cgactaaagc aagtacatct
     7981 ttatctggca aatcgcttaa attgctccaa ctagcaactg cagttttgtt ttcagtgatt
     8041 gttcccgtct tatcaagtaa aagcaagttt aagttagctg catcttggat accagttaaa
     8101 tcagctgtta agacgccttc tttacttaaa cgggttgctt caaatgaatt ggacaatgca
     8161 aaggttgacg gcatcgcaac cggaattgaa gcgatgaaca tcatggctaa gaatggcaac
     8221 atgttgataa acgtatcaaa attaccaccc ttaaagaatg aagcaatgat aataactaag
     8281 gtaagtacac cgtcaagtag gcaaaggtag taaataatct tagttaaaag ttgttgcaag
     8341 tgaccaggtg cagctgaatt gttgatcaag ttaatggtct taccacttct tgaatcttta
     8401 ccagttgcag taacaattgc taatccatcg ccttcaacaa cagtagtacc agcataagct
     8461 gtgtcatcaa tgttcttttt aacgggctta gattcaccgg taattgagct ttcatcacag
     8521 gcgatcttac cgctaaccat ttttacatcg gctgcaagta catctccacg ttgaagtgag
     8581 attaagtcgc ctctaactaa ttgcttagag tcaattttga tccacttacc atcgcgttct
     8641 acagccacct taggggttag cttatgtgaa atggtattta atacccgccg tgactgtttc
     8701 ttcttggatg caccgttaaa agccgcaaaa agaagcatca acaagacgaa caaagattga
     8761 atccatttgc ctaagataca ttcgaggatt aaggcacctt ctagaaccca ggcagaaaga
     8821 ttccataatt ttgatagaaa ttccttaaaa aagttgtatt cgggttcagg tgcttcgttt
     8881 aacccatctt ccttaagtct cttatctgct tcggcttgag ttaagccatg aaatttttca
     8941 gacattttat tccctccaaa tctaccttaa taaagtagca catatgttgt ttgaatgaaa
     9001 atactaaatt aaaatataag atatagaaat ttttaataag agatacaact aaaataaaaa
     9061 agatagatta ttaatgaata ttaaacaatt acgctacttt ttagtagtag ccaaagaaaa
     9121 gcaaatcact tcagcagcta aaagactata cattgcacaa ccgccgctga gttatcaatt
     9181 aaagcaacta gaaatagaac taggagcaca attatttaag cgtactgctc atggaattga
     9241 attaacagat gctggacaaa ttttgcagag ctatgctagt gaaattctct ctttatcaga
     9301 aagcgtgaaa aatcaggttc ataaaactgt ttcaggtgaa ctaggcacga ttgcaatagg
     9361 catggcttca tcatcaactg gactaattcc tatgaaaagt tttcaagatt taactaagtt
     9421 ttatccggaa atcaactttg atatttatga agataatacc tttggcatta tcgataaatt
     9481 ggaaaagaag acaatcgatt taggaattgt gcgtacgcct tataatcgta atggcttaaa
     9541 tgcaaaaact ttaactactg aaagaatgat ggcagttact gttgatccca aatttaagga
     9601 taagacggga ttaaggatta aagatctaaa tgagcagccc ctcattattt atcgaagatt
     9661 tgaagaaatt tttaaccaga cttttgctca tcatgggatt aagccgtttt atgctgttaa
     9721 atgtgatgat tctagaacag cgattacttg ggcgaagaga aaaatgggga ttgctcttgt
     9781 tcctgaatct attgcttcta cgtatgcacc tgatgatctt attcctatta aatatagtaa
     9841 ttggattacg catttgcaat tagtgaggcg caaggatcaa aaggtgacgc ctttaatgaa
     9901 aagaataata gattcactaa gccgttaaga ttgtaacttc tacctaattg atccttaatt
     9961 attgtaagct gatacataat ttgaattagg aggcgctata atgactgact taattcatgt
    10021 ttattccgaa attggcaaat tagaaacagt tatgctgcat cgaccgggaa gagaattaga
    10081 aaatctttca ccggatatct taaatcgaat gttaattgac gatattccat atttaaaaat
    10141 agctcaaaaa gagcatgact attttgccca cactttggaa aaatagggag ttcatgtcgt
    10201 ttatttagaa gatttattag ctcactcttt gactaatgaa gatgtccgta caaaatttgt
    10261 agatcaatta ttagaagaat ccaatataaa aaagaagatc cattacatca attactgatg
    10321 gactatttaa tagcaatgcc agtaaatgaa atggttaagc aaataattgc tggtattaga
    10381 aaaaatgaaa tgcaaaatgc aactccttca ttagccgatc tagctgaaaa tccagattat
    10441 ccattttatt tggatccaat gccaaatgtg tattttactc gtgatcaaca agcaactatt
    10501 ggtaatggca tgactattaa tagaatgacg tttagagcta gaagacgtga gtcattattt
    10561 atggaaaccg ttttaaagca tcatcccgac tttaaaaatg ccaatattcc tatttggtgt
    10621 gatcgttaca ctcatggacg tttagaaggt ggcgatgagc tgattttaaa caatcatgtt
    10681 tttagcaatc ggtatttctc aaagaacttc cgctgccgca atcactgacc ttgctcatag
    10741 cctgtttggt cattctagtt atgacacaat tttagcaatt aaaataccac ataatcatgc
    10801 catgatgcat ctggatacag tctttacaat gattaattat gattagtgta ctgttcatcc
    10861 ttttatttta gacaaatcag gaaagattga tatttatgtt ttagagcaag atgatcatgg
    10921 tgagattaaa attaccccag aaactgattt gatcaaagtg ttaaagaatt atttgcactt
    10981 atcggagatt gacctaattc caaccggagg tggggatgca attgcagccc caagagagca
    11041 gtggaatgat ggctcgaata ctttggctat tgcgccaggt gaagtcgtta catatgatcg
    11101 taattatgta tcaaatgatt tgttaagaaa gcatggcatt ttagttcatg aaattcattc
    11161 aagtgagctt tctcgtggcc gtggaggtcc aagatgtatg tcatgtccac ttgttcgtga
    11221 agatttgtaa gaggcgtcaa aatgaaatat ttacaaaatg tgtttcaagg cagaagttta
    11281 ttaaaatgca aagactatac tccaacggag cttaactatc taattgattt tgcacttcat
    11341 ttgaaggaac taaagaaaat attccgcatg aatatttaaa aggaaagaat atagctcttt
    11401 tatttgaaaa atcttcaaca agaacacgtt cagcctttgt agttgcatgc aatgatttag
    11461 gcgcaaatcc tgaatatatg ggtgctggtg aaattcattt aggtaaaaag gaaagtattg
    11521 aagatactgc caaggttttg ggcagtatgt ttgatgacat tgaatatcgc ggttttgctc
    11581 aaaaagatgt agaagatttg gctaaatatt ctggtgtccc tgtttggaat ggtttaacag
    11641 ataaatggca tccgacccaa atgttggctg actttatgac tattaaagaa aagtttggac
    11701 atttaaaggt acttacttta gcttatgtag gcgatggacg tgataatgtt gccgacagtc
    11761 ttttagtggc tggcagcatg cttggagtta atgtacacat agttacgcca aagcctttat
    11821 tcactcaccc tgatgtacaa aaaattgcag aaggttttgc caaagattct ggatcaagaa
    11881 atttgattac tgatgacatt gaacaaggcg ttaaaggtgc aaatattatt tatactgatg
    11941 tctgggtatc aatgggtgaa aatgactgga gtgagagaat caaattgtta aagccttaca
    12001 cggttacaat gaatatgatg tatatgacag gcaccccgga tgatcaacta atctttatgc
    12061 actgtttgcc tgcgtttcat gattgaactg ctaaagttgg caaagaaatt tatgaaaaat
    12121 atggtctaag tgaagtggaa gttacagatg aagtctttaa ctctcaatac gcttggcaat
    12181 ttactgaagc ggaaaataga ttgcattcta tcaaagcaat aatggccgct actttgggca
    12241 atttgtttat tccgtcagtt gatgaaggaa gtaaataaag atgaaaagaa tagttgtagc
    12301 tttcggtggc aatgctattg aagcaggtga taatagtgca gctgcccaag aaaagcaggt
    12361 taaaaagaca atgaaggttg ttgctaaaat gattgaaaat ggtgatcagg tagcgattgt
    12421 tcatggtaat ggcccgcagg ttggtaattt gcttttgcaa caatacaaag gttcaagtaa
    12481 agataatctc gctatgccgc ttgatacagt agtatcaatg actcaaggca gtatcggcta
    12541 ttggatgcaa aaggccttag acgatcaatt taaacataca aattatccac atcaagctgt
    12601 tgctttaatt actcagataa tagttaatgc gaatgatcca acttttaaga atccaactaa
    12661 actaattggc ccattttata catttaacga aatgcagagg taaaaaatct atcatcctga
    12721 atatacttat aagcaagata caggtcgagg ctatcgtcaa gtagtttctt ctccaaagcc
    12781 cgttaaaatt attaatgcac caggcattga cactttacta aagagcaagt ttgttcctat
    12841 tgctgccgga ggtgatggaa ttcctgttgt agtgaaagac gatagtttgc aaggcgtagc
    12901 aggagtaatt gataaagact tcagtgccgc aaaactagct gaagatattc aagcagatga
    12961 attagttatt ctaactactg ttgacaatgc ctacgtgaac tataatcaac ctgatcaagc
    13021 tcctattgga aaaataaaga ttgatcaatt aaagaagtat ctagaagctg gccaatttgc
    13081 tgcaggcagc atgaagccaa aaattgaagc tgtcattgat ttcgtagaga aaacaggaaa
    13141 gactgcaatt attacttctt taagaaatgc aagtaaactt gatgatggag taggtacaat
    13201 tgtttataat taactgcggt gagatataaa tgaacatttt tcaagaagga aatccgcaaa
    13261 atattgctca ggtattagct ggaaaagatt atcgtgtagc tttgcagcaa gctattttta
    13321 aaaagtatcc tgatgcgact ttggttgata taaacttaaa tatcccgggg ccaattaaaa
    13381 ataatcgata tttaatcaaa ttatttgatt acggaattaa acaattagaa gaaatatggc
    13441 agaataatgg atatgactat aaattagtaa aagcattaaa taatgatgct ggatgtgaaa
    13501 atttctatgt tttgcgagaa tctagcaaag tagttaaatt atctacaatt ttatttgaag
    13561 aaaataataa aataggacga ttatttgatg ccgatgtatt aattaaaggg aaaactgcac
    13621 tttcacgcca agagcttgaa tactctagtc gccgctgcta tttatgcaat cgccctgcta
    13681 aagagtgtgc tcgatcacgg cgacactcag tagaagagat gcaaagatac atttctagtt
    13741 tatatgcgaa gtatgtaaat aattaaaacg ggatgggagg ctaatcatcc cgttttttca
    13801 tttaaatctt aaaaaaagct aacgaaaaat acataaaatg ttctaaaata taagtaaagt
    13861 tatgaatata tattgtaagg aaaactatga aattaaagaa aaaccaagac aatttaaaac
    13921 aaattgcttc attgattgaa tatgcttttt taaaagattc tgatttgact acagatagta
    13981 actttatgcc ccgatatgat catagtgatg gatatggata ttttgatcaa gaaaaattga
    14041 ccagttatat gatggtcaat aagtttaaag ctgagatatt tggtcatcat gttccactgg
    14101 caggtattgg ttatgtggca tcatatcctg aatacagagg acgtggacat atatctaaat
    14161 taatgaaaga aattcttttt gatttgcatg atcaaaaaat cccagttgca aatctagctc
    14221 cattttcaga aaaattttat cgtcattatg gttttagcaa tagtatttac caaaaagaat
    14281 atcgcttttc gggggctgca cttgcttctt tcagattacc acgcaaaggt aagataattc
    14341 gtggaaaatg gaatgatttg attgttcaaa atggtgtgat tcaattatat gaacgtcagt
    14401 tgcatactga cgatgaaaga aatacgatca tcagagaagc ttggtggtgg aatagattag
    14461 atgattatta tcatcatcga gagattgctg tttacttcga tgaagctggt cggccgatga
    14521 gctacttgat ttatcgcata attgataact gttttatggc tgatgaatta tattcaatta
    14581 cgcctcaagg attattaagc atattaggct ttatggcagc tcatataggg tcaattaaag
    14641 agttttgtat gacattgcat gagaagtctt tattggctga actttttcca gagcaaaatg
    14701 aattggatat tcaacttcat ccatatatga tgagtagaat tattgatttc caaaaagtct
    14761 tggcatgcat gcgcccattg caagagggta cttttaacat cgaagttaat tatgatgatc
    14821 agtgtccatg gaatattggc gtttggcaat taactaatta tgatcaccaa gttaagtgtg
    14881 aacgaaaaga agatgaacta gttgatttct ctggtccaat tacaacatgg actcaaatct
    14941 tattaggacg tttaactatg gaatccgcaa ttaaacttgg tttgatcaca gattatcgaa
    15001 ttaaaaagtt ggactttgta aaaggtaaag tctcatttta tgattatttt tagaagaagg
    15061 tatccaaaat gagtaagcaa aagaaagtta gattactaaa atttttaagc gtggtagtta
    15121 gtggaataaa tgtggttatt tcgctattga ttatgttcaa caaatatcaa attagaaaag
    15181 ataaaaaaca aatatcagat gaaggtcatg ccccattgga tgaaaattaa ctatgaaaaa
    15241 attgagaata gcatacttta accaacttgg tagaagacaa ttagatcgaa ttgtagacca
    15301 atttaagcaa aaacattctg atgtagaaat tgaattaatt ggaatgggac acgatgaagc
    15361 ttttgataaa ttagccaaaa atgaagttga tttagcgatt agtgatttgc gcgatgatca
    15421 gctcgatttt aagaaagaaa tcttaggtca ggaagcagta atggctattt tgcaaaaggg
    15481 tagttatcct agcggtgttc agatgatcaa taaagatgat ctagctgatt taacctgttt
    15541 tattgtagct aagcctgaag aagaggctgc agaactccat ttatttaaag atatttatca
    15601 gattagaagc ccattcattg cttcaaattc cgtagaagag gcagcattgt tagtagcttc
    15661 tggatcagga tattttttaa tgaatgaagc aaccgccagt ttaattagta atgatacttt
    15721 acaacgattg tttttattgt ctaatggaca acaaatgtgg caaaagattg cagcttttta
    15781 taccaatgaa gatgcagtaa ttaaagattt tattttgtta gctaaaaaag tatattaatc
    15841 tatcttggaa cagcaaaata ctgtaaaaat aaaaatgcgc tgattgtaaa attaagttga
    15901 acacttgata aaaaataaaa agtccattcg gacctgtttg atagaatgta gttaccacac
    15961 aacatttaga aacgaggtca aaatggactc tttacattct accatgaatc agcacattaa
    16021 aggcaagcat ttatcattcg aggaaagagt tattattcaa ttgcgtttga aagatggcta
    16081 ttctttgcgt gccatcgccc gtgaattaaa ctgttctcct tctactatca gctatgaggt
    16141 taagcgcggt actgtagaac tgtatcatgg caaagtcaaa agatataagg ctactcaagg
    16201 gcatgatgca tatcaagccc atcgtaaaaa ttgtgggcgc aaatcagact ttctcaggaa
    16261 aactcaattc atgcgctatg tccacaagca tttctttaaa gacggctggt cgcttgatgt
    16321 gtgcagtaat cgtgccactg ctgttggcgc atttagcagc agagatgttg tctgtactaa
    16381 gactctttac aagtatgtcg accaaggtct attagatata cataattacg acttgccaga
    16441 gaagcttaaa cg
//
