LOCUS       gnlProkkaFIBKDMCK_41   15163 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FIBKDMCK_41.
ACCESSION   gnlProkkaFIBKDMCK_41
VERSION     gnlProkkaFIBKDMCK_41
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:33:58
            Original ID  :: gnl|Prokka|FIBKDMCK_41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1417
            Orig. end    :: 16580
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15163
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:11161]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..11161
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..15163
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15163
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             824..1090
                     /locus_tag="ctg41_3"
                     /transl_table=11
                     /translation="MDYLVIKTIIWIFFITSAILEVNYKKKHGELDKRARKQAILGTFL
                     IVTTIFDEGYENKILYIIVLIALLVYIVLVIYRLVMAIKDRKK"
     CDS             1111..1452
                     /locus_tag="ctg41_4"
                     /transl_table=11
                     /translation="MKAIYRGRKVDVWQVSRDNVQPDWVKDAFEHNGLRWLHGSGNKVR
                     IYWPAVTRAKKGIIRTILNGISASFVSIAGGSASMYDIGFEGDVIDFTNSKVVTAEKFA
                     KKYRIVSED"
     CDS             1563..2009
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 65.7; E-value: 7.9e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_5"
                     /transl_table=11
                     /translation="MIKAAIFDLDGLLVDTEIVSLKIYQELLSEYGYSFTKEEYAKHYS
                     GKTEKENIKRFIDTYNLSVSYQECLDEVLNIERKLISQGVELKVGVKSLLMYLKENNYK
                     VTLATSSTKDRAISILKGHDILSYFDEFVFSEDVTLVSLIQKFS"
     CDS             2078..2212
                     /locus_tag="ctg41_6"
                     /transl_table=11
                     /translation="MAAYNAHIPVICIPDMKRPAKEYLEKTIAVCKTLNDVIDYLKTK"
     CDS             complement(2375..3349)
                     /locus_tag="ctg41_7"
                     /transl_table=11
                     /translation="MRYIKFTLLIYSFLLTWGITTNSISADEVTPTTTSETTVTPQSQS
                     TSVDSNDEDAAIEEKFYSHDVTIDEYNQNVANFNKVNTDTVKTMVTENSNNLDQVLYIG
                     RPTCYFCRQASPHLRDFNQLINNQLYYYDIDAEPSAHDFAFKEIGIPGTPTTMRLKNGK
                     VVSAWIGGEKTGQEFYDFLFSADANKLADSYTIKKTVSTDTSNPVITNNQNVEPTVKHI
                     PTNISQLKEEKTTTELVNTTSQPFKPVKKIQNPATTTNKKNKNSVLPQLGVVPLYHQPL
                     FKLPIPKIPKQLERTIMLITFLVLYLGFLICLWLSWKEINKRK"
     CDS             3703..3900
                     /locus_tag="ctg41_8"
                     /transl_table=11
                     /translation="MNGVKAPVKISAWTNFKTLFNGASGWWATYASGYIGDYLDFTNRK
                     IISERKFKKKYKIVDTYVNK"
     CDS             complement(3939..4202)
                     /locus_tag="ctg41_9"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLFLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFEATDDKHPLNRIDFGLQLLFIFISIIKFFLISGR"
     CDS             4435..4608
                     /locus_tag="ctg41_10"
                     /transl_table=11
                     /translation="MNNNFVQIDKKELAHIIGGRNSYDYIDSGKFGYDIGCTIANTKFF
                     KRLRHSNQNICS"
     CDS             4738..4995
                     /locus_tag="ctg41_11"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEDMS
                     YLDYIQTPKMIIVAIFCLIGGSTLLYLLDTTMKVNKHMKG"
     CDS             5001..5195
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_12"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.6e-17,
                     bitscore: 53.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKEFTVLTECELAKVDGGKRGPNCVGNFLGGLFAGAAAGVPLGP
                     AGIVGGANLGMVGGALTCL"
     CDS             5213..5419
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_13"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 5.2e-12,
                     bitscore: 36.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLDKRFTIMTEDNLASVNGGKNGYGGSGNRWVHCGAGIVGGAL
                     IGAIGGPWSAVAGGISGGFASCH"
     CDS             5852..5971
                     /locus_tag="ctg41_14"
                     /transl_table=11
                     /translation="MKFEVLTEKKLQVIVGGKQEGGTKTYDKVCRFKFLGICK"
     CDS             5973..7265
                     /locus_tag="ctg41_15"
                     /transl_table=11
                     /translation="MTDIVDIYNRYNIIIYAVGLFISVACDYLFFYLITPINRSKKQNI
                     LFTIITFPIVFLYHGGGDLGAFCAELFEVSAFYIVYKRRKRDYQVLGRILILLLYSYLS
                     FEIEFLLSQIISQYISALPIDTIVINILEYYILMKTDIIKNLDDEYGKTFFYLIIYLLV
                     SFAGIYYLTGYLFKVDKVLYLILLVVIIVQLIFSLYIYNNSKKIRQDKLSLQQIKDLKI
                     YTQQLESSQRSLRKFKHDYQNMLVSLKLSAKKNHDKELIDKLAEYSSKILEDKVLWQFN
                     DVDNIKDELLKSLFISKLNRIFQDNIQYSFECRDVIDSLSNEYNAFDIIRILGITYDNA
                     IEESLELGDEARIDTMVYRENGELEIEIKNRCRNTDLTIQDMKKSGFTTKKNHDGLGLA
                     NIEELSQPYNDIFINYQIKDGWFTFLMVMSI"
     CDS             7279..8073
                     /locus_tag="ctg41_16"
                     /transl_table=11
                     /translation="MEEYGIIICDDEKDQVRRIHDLVKYAIWSLEDSADSKDKEFKITL
                     EANSYIEVADYLEDNKVDSGVYFLDIELSRDKADRDGIDLAEFIRQRDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDSDEVIQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDILYIITTPKSHRLEIVTVNGMGEFTGDIKKLEAENDFLEKISQSCLANPS
                     NIVEINLSTRVISFKDGYKETFPRRSKAKMKSLIERYNLKTV"
     CDS             8110..8349
                     /locus_tag="ctg41_17"
                     /transl_table=11
                     /translation="MVEIGIIILLVVGFMVISRLKVNFTKNSRYAGFLLLILLDLNGLM
                     RTPMLTVRGLILLGTLMIFVIMLIKEIRQNRKYS"
     CDS             8594..8791
                     /locus_tag="ctg41_18"
                     /transl_table=11
                     /translation="MKINKKFYKNYTFYIGLVMLSIAVGSIFLDKGYFLFTIIDILFTC
                     LGIKYVYQSLVLTKRYERNR"
     CDS             9002..11161
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 313.3; E-value:
                     5.6e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_19"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.3e-45, bitscore:
                     143.6, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1080.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKYKKYYIPQVDESDCGVASLAMILKHYGSSLSLAYLRNIAKT
                     TMEGTTALGLVKTAQTLGMETQAVKADMSLFGMKDITYPFIVHVVKEETLLHYYVVLKA
                     TPNYILIADPAPDVGITKMSYERFEKEWTGITLFIVPGIEYKPTKETRQSLISLFSKLF
                     KQKQLIVNIVLAALLITIISILGSYFLQGIIDTYIPNGMHSTLAIIAFGLLVIYVFNSI
                     FTYARDFLLAILGQRLSIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVVSIFLDVSIVVIMGIILAIQNLKLLGITLISLPIYTIIILTFTKAFERLNNKQMES
                     NAILSSSIIEDIQGIETIKALNSEQMRYRKIDSQFVDYLRKSLAYIKTDSLQQALKLFI
                     QQTLNVIVLWLGANLVISNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDRKAVHDVTQLQGNIIFQDVDYRYGYGENILDKVNLTLKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFAPVSGSIKLNNHDINNIDKHTLRSYINYIPQNPYIFAGTIE
                     DNLRLGNRSNVTDEDILMACKIAMIDTDIAKMPLQLKTKLDENANILSGGQKQRITIAR
                     ALLSPAQVLIFDESTSGLDAITEKKLIDNLMKLKSKTIIFIAHRLSIAKRTNNILVLDG
                     GKIVEKGRHDELLAKKGYYYNLINS"
     CDS             11177..11401
                     /locus_tag="ctg41_20"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSARFRNFSTMIIIPFTILLLAVVIFSFFGKKEI
                     TIQGAGTLEALGNNPVIQSTVNSPIEKII"
     CDS             11452..12324
                     /locus_tag="ctg41_21"
                     /transl_table=11
                     /translation="MNIQDKGKLYNSQKEILDRQLAALNLLKQGVQDNHDSFGEDDEFG
                     YRNDLKSYLQQRNTYLTENTMIQDKSKNDKAKQSSINNELKKQGGSATSIADFDSSKYD
                     IDINNQKMSDLQSSKLSSIDQEIIKIKQNISELNANIDENNNTNREYKVKAVRDGILHI
                     NDEYSESHYISAGANLAQILPILKNQKTLKIKAYISTADISSIKVGQKVRFKVTRNVPK
                     PIILTGKIHKISISPVEIGKENYYQIEAKTDIQNTNRDLLKYGMQGQMVVITGKTTFFE
                     YYKDKLFNR"
     CDS             12767..12988
                     /locus_tag="ctg41_22"
                     /transl_table=11
                     /translation="MTQVTATELKNNLGKYLKKSEFEDIYITKNGVIVSVLSNPNQSKL
                     QMLDDLKGIAPDMNMTDEELRSERISNI"
     CDS             12988..13392
                     /locus_tag="ctg41_23"
                     /transl_table=11
                     /translation="MKKVLVDTCVIIDILLDREKFVDDSYSAVSKLIRKGDTICTTAKA
                     MTDIFYIVHHSLHDNDKTKEVLLKLSRVYQILDTKEKDTIMAITSDVADYEDAVMVETA
                     IANKVDFILTRNIKDYKKAKIKVISPTELN"
     CDS             13737..14366
                     /locus_tag="ctg41_24"
                     /transl_table=11
                     /translation="MFRSSSEKFKLYYYVSSLFPIHISVLVFIFSSKLENNNCENLFKV
                     SSTSSKITILIMLLSILVDLYSLVRVIQLLNNQKKLTKALGTNSVRISNEYNGGLRDFL
                     LSFIVPAITTFSADENPLTMIIFILLFQFIVYVFYKNSSDFFPNISLMFMGYSVFKVDT
                     YDLGGIEYVFGKTKNIDDIILKKVDVIMIGDKNYPNNVAIILEKKV"
     CDS             14371..14619
                     /locus_tag="ctg41_25"
                     /transl_table=11
                     /translation="MNINKIFLLNFNDTNDFNIKQVAIENDKVVSFSKSIKNISEYGMK
                     NYFDLAESLENPKKYSISLGENDEKTYHIDLLEKIRS"
     CDS             14673..15161
                     /locus_tag="ctg41_26"
                     /transl_table=11
                     /translation="MTKYTQKFKLDLIQEYLDTGCSQRCLENKYSLPKDTLKKWWTVYN
                     LKGPEGLKLRHFKRKFTVDFKLRVINYYLNNDVSMSKVAASHNLLCSQISIWLKLFMEG
                     GSEALKPKKKGRPSKMSKMTKKDARKILKKESDEIAALKSELRQVKMERDILKKSLTLF
                     "
ORIGIN
        1 acgatttggt ggtagtagaa aatttgagaa gtaaaaatat gctcaagaat cacgctttag
       61 ctatgtctat atccgatgtt ggttggagaa actttttaca gaaattggat tataaagcta
      121 atttgtataa cagaacagtt atatcggtta atcctaaaaa tacaacacag acttgttatg
      181 cttgtggctt tataatggga acaaatggaa ctgataagtt gaatctcaag gatagagaat
      241 ggacttgtcc taattgtcat gaacatcata ttagagattg gaatgcagct aaaaatattc
      301 tagctaaagg attagataag ttagaaaaac caaaaaactt agctaaagct aagtaaaggg
      361 tgcgtttggc agcttgcgcc acccgtatat tattgtatac aaagtgctgt ggtaaattga
      421 tgtgtaagac gtaagtatct ttttttggat atttatgctg tattttaccc acggaagagt
      481 gtgttagtag agccgaaagg cttgaacnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      541 ngtatctttt tttggatatt tatgctgtat tttacccacg gaagagtgtg ttagtagagc
      601 cgaaaggctt gaacactcac aagccccatg tctttagact ggggtgagtt gacatagttg
      661 ggaatagtgg caagacagcg atgttttgtc gctatttttt taacgtacat ggatatgttg
      721 ttaaccaaat aagcagaaaa gagtgttaat taagaaaata cagaattaaa tttaattagg
      781 atagtataat aatggcaaaa aatagagaat aggtggtgga ataatggatt atttagttat
      841 taaaacaatt atttggatat tttttataac atcagcaatt ttggaagtta attataagaa
      901 aaaacatggt gaattagata aacgagctag aaagcaagca atattaggaa catttctaat
      961 agtaactaca atatttgatg aaggttatga gaataaaata ctatatataa tagtattaat
     1021 agcactgttg gtatatatag tattagtgat atatagatta gttatggcta ttaaggatag
     1081 gaaaaagtaa taagaaaggt gataaagcaa atgaaagcaa tctatagagg tagaaaagta
     1141 gatgtttggc aagtgagtag agataatgtc cagcctgatt gggttaaaga tgcttttgag
     1201 cataatgggt tgcgatggtt acatggtagt ggtaataaag tcagaattta ttggccagca
     1261 gttactagag caaaaaaagg aataatacga actattttga atggtatctc agcttctttt
     1321 gttagtatag ctggtggcag cgcgtcgatg tatgatattg gttttgaggg agatgttatt
     1381 gattttacca attctaaggt tgttacagcc gaaaagttcg ctaagaaata tcggatagtg
     1441 tctgaagatt gaggtaaagg tattaaattg tctatgacaa gataatcaac ttttatgtca
     1501 aaataagatt gaataattat atgatataat aaatatgtat tacgaaaggt ggttgattta
     1561 ttgtgattaa agcggctata tttgatcttg atggattact agtagataca gaaattgtat
     1621 ctttaaaaat atatcaggaa ttattatctg aatatggata tagttttact aaagaagaat
     1681 atgcaaaaca ttatagtggg aaaacagaaa aagaaaatat taaacgtttt atagatacat
     1741 ataacttatc ggtatcttat caggaatgtt tagatgaagt tttgaatatt gaacgcaaac
     1801 ttatttcaca aggtgtggaa ttaaaagtag gggtaaaatc tctacttatg tacctaaaag
     1861 agaataatta taaagtaact ttggcaacat caagtaccaa agatagagcg atttctattt
     1921 taaaggggca cgatattctc agctactttg acgaatttgt atttagtgaa gatgtaacac
     1981 tagtaagcct aatccagaag ttttcttaaa agcttgtgaa aaaacaaatg tatcaactaa
     2041 tgaagcaata gttttagaag atagtgaaaa tggtattatg gctgcctata atgcacatat
     2101 tccagttatt tgtatacctg atatgaaaag accagcaaaa gaatatttag agaaaactat
     2161 tgctgtttgt aagacgttaa atgatgtcat tgattattta aaaacaaaat aacagttacc
     2221 gcataataaa aatagtgtaa ttaaaaaagt taaatataaa gataggacca atttactaat
     2281 ttatgcaaaa atgtagtttt gaatctacaa aaatcgatta tttgcataaa ttttctaatt
     2341 ggtcctattg ctatatcgca tatttacttt ttatctattt ccttttattt atttctttcc
     2401 agctcaacca taaacatatt aagaatccca aatatagaac tagaaaagta attaacatta
     2461 tagtacgttc taattgctta ggaattttag gaataggaag tttaaataat ggctgatgat
     2521 aaagagggac aacccctaat tgtggtagaa cagaattttt gtttttctta ttagtagttg
     2581 tagctggatt ttgaattttt ttaacaggtt taaatggttg tgaagtagta ttaaccaatt
     2641 cagtagtagt tttttcctct ttaagttggc ttatatttgt tggtatatgc ttaacagttg
     2701 gttcaacatt ttgattattt gtaataacag gatttgaagt atctgtgctt acagttttct
     2761 ttatggtata ggaatctgct aacttgttag catctgcaga aaataaaaag tcataaaatt
     2821 cttgtcctgt tttttcgcca ccaatccaag cactgacaac tttaccattc tttaaacgca
     2881 tagttgtagg tgttccagga attccaattt ctttaaacgc aaagtcatga gcactaggtt
     2941 cagcatcaat atcatagtag taaagctgat tatttattag ttgattaaaa tcacgtaggt
     3001 gtggtgaagc ttgtcgacaa aaataacaag taggacgtcc aatgtaaaga acttggtcta
     3061 aattgttgct attttcagta accatggttt taacagtatc agtattaact ttattgaagt
     3121 ttgccacatt ttgattatat tcatcgattg taacatcatg agagtaaaat ttttcttcaa
     3181 ttgcagcatc ttcatcatta gaatcaacag atgtactttg actttgaggc gtaactgttg
     3241 tttcggatgt tgtagtaggt gtaacttcat ccgctgatat actattcgtg gtgattcccc
     3301 aagttagtaa aaaagaatat attagtaaag taaatttaat gtatctcatt ttttcaatcc
     3361 ccctaatcgt atatatgtaa ttattgcaaa taatgtctac atagtgtgat aaactgctgg
     3421 aatggtagca ataactactt atttggacta tttaccaaat aagtaagaaa tagtgctagt
     3481 taagaaattt agcattggat gtattatgaa aatagtataa tgaagatgta attaatagag
     3541 ctctttaatt atatgtagaa ggtgatttct atgaaagcaa tctataaagg taaagaagta
     3601 taaatatggc agataagtaa aacagcagaa caacccgaat ggataaaagc agcatttaaa
     3661 gctaactatc taaagtggtc aggtgataaa ttgttattta ttatgaatgg agttaaggca
     3721 cctgttaaaa ttagtgcttg gacgaacttt aagactttat ttaatggagc ttcaggttgg
     3781 tgggcaactt atgcaagtgg gtatataggc gattacttgg atttcactaa tcgaaaaatt
     3841 atatcagaaa gaaaatttaa aaagaagtac aaaattgttg atacatatgt taataaataa
     3901 gcctatcaga tgtaatttga tacctgatag gcttattgtt atcttcctga aatcaagaaa
     3961 aatttaataa tagaaataaa gataaatagc aattgtaatc caaaatcaat tctatttagt
     4021 ggatgcttgt catcagtagc ttcaaaataa tggaaatgta gcatggttgt aaccaaagaa
     4081 gaaaaggcta gtataccaag atgaattaga tttccatcaa ctaatgtcca gatcaatagg
     4141 aataaagtaa ttagtgaaac agaaattttg ctgaaattaa tattattaga aaaactattc
     4201 ataattttta cctcaattca ttataaaagt atttttatta ttacatagaa agtaataaat
     4261 tgaggagatt tttccaattt ggtaataaat agtgcctatc tggttgaaaa aagagaataa
     4321 gaataaaatt tagcaaaatt agaagaaata atcaaaaaga gcagatgaag tgaataatca
     4381 taagtgtaaa ttatagctat aataaatttt taaaaattat gaggtgttga agttatgaat
     4441 aataattttg tacaaattga taagaaagaa ttggcacata taattggtgg aagaaattct
     4501 tatgactata tagatagtgg taagtttggt tatgatatag gatgtacaat cgctaatacc
     4561 aaatttttca aaagattgag acattcaaat caaaatattt gtagttaaaa agaaatgtaa
     4621 ccaactaggt atagaataac gtattttacg ctaaattgat atttgaatac agaatgataa
     4681 tacaataaaa gtgtaagtat atgtttcaca agtgttttag aaaggatgtg tttttacatg
     4741 ctaaaaaaac tatgggagac ttggttggat ggtggattca ttagaggaaa gaagagatat
     4801 gttattgctc cagttatttg ggcactattg attccactag gaatatggtt gtttggtaat
     4861 gaggacatgt cttatttaga ttatatccag acgcctaaaa tgataatagt tgctattttt
     4921 tgtctaatag gtggtagtac actactttat ttattagata ctacaatgaa ggtaaataaa
     4981 catatgaaag gatgattatc atgatgaagg aatttacagt attgacagaa tgtgaattag
     5041 caaaggttga tggtgggaaa cgtggaccta actgtgtagg taacttctta ggtggtctat
     5101 ttgctggagc agctgcagga gttccacttg gaccagctgg tattgtaggt ggagcaaact
     5161 taggaatggt aggcggagcg cttacttgtt tataatatag gagtgattta aaatgaaaaa
     5221 tctagataaa agattcacaa ttatgactga agataactta gcatcagtaa atggtggtaa
     5281 aaatggttat ggtggtagcg gaaatcgctg ggttcactgt ggagctggta tcgtaggtgg
     5341 agctttaatt ggagctatcg gtggaccttg gtcagccgta gcgggtggaa tttctggtgg
     5401 atttgcaagt tgccattaat ataaatataa aaaattagaa aatagatcta tttttctgca
     5461 agtagtgtca agtgtaagtt atagtatata gctaaatttg acactacttt tatttttaat
     5521 agaatataat atattttggg aattaggaaa taagtacatg ataatttagg ttacagtaat
     5581 agttgtatat attatcttta tcagtatcta tactagtaaa aaagaagata gacattacaa
     5641 gtcatttgat gagaaagcta tagaaaagaa taagaaagta ggttatgtga ggcatgggtg
     5701 ttaaacttta tgtggtggct ataggctata gttttaagaa tttcatccaa ataagcatta
     5761 aaatgaaccg aatatgataa aaaagcgaat aaagtagatt aaaaaatgtt aaactatatt
     5821 tgtaataaag ataacaaagg agagattttt tatgaaattt gaagtgttaa cagaaaagaa
     5881 gttacaagtt attgtaggtg gtaaacaaga gggaggaaca aaaacttatg ataaagtatg
     5941 taggtttaaa tttttaggaa tttgcaagta aaatgacaga tatagtggat atatataata
     6001 gatataatat tataatatat gcagttggtt tatttattag tgtagcatgt gactatctat
     6061 ttttctattt aattacaccc attaatagaa gtaaaaagca aaatattcta tttacaatta
     6121 ttacatttcc gatagttttt ttgtatcatg gaggtggaga tttaggtgct ttttgtgccg
     6181 aactttttga agtatcggct ttttatatag tatataaaag aagaaaaaga gattatcagg
     6241 tattgggaag aatattaatt ctcctactat attcatatct ttcatttgag atagaatttt
     6301 tactttcaca aataatttca caatacatca gcgcacttcc aatagacact attgttataa
     6361 atattttaga atactatatt ttaatgaaaa cagatattat aaagaattta gatgatgaat
     6421 atgggaagac attcttctat ttaattattt atttattagt cagttttgca ggaatatatt
     6481 atttgactgg ttatttattt aaagttgata aggtgttata tcttatatta ttagtagtta
     6541 ttatcgtaca attaattttc tcactatata tctacaataa tagtaaaaaa attagacaag
     6601 ataaattaag tttacagcaa attaaagatt taaagattta cactcaacag ttagaaagta
     6661 gccagcgaag tttacgcaaa tttaagcatg actaccaaaa tatgttagta agtttgaagc
     6721 tcagtgcaaa gaaaaatcat gataaagagt taatagataa actagctgaa tattcgagta
     6781 agatcttaga agataaagta ttatggcagt ttaatgatgt tgacaacatt aaagatgaat
     6841 tattaaagag tctatttatc agtaaattga atagaatctt tcaagataat attcaatact
     6901 cttttgaatg tcgggatgtg atagatagtt tatcgaatga gtataatgca tttgatataa
     6961 ttagaatatt agggattacg tatgataatg caattgaaga aagtcttgaa cttggcgatg
     7021 aagctaggat agatacaatg gtttatcgag agaatggtga gcttgaaata gaaattaaga
     7081 atcgttgtcg aaatacagac ttaacaattc aagatatgaa aaaatcgggt tttacaacta
     7141 agaagaatca tgatggatta ggattagcta atatagaaga attaagtcaa ccttataatg
     7201 atatttttat caattatcaa attaaagatg gttggtttac tttccttatg gttatgagca
     7261 tttaaggggt agtttaattt ggaagaatat ggaattatta tttgtgacga tgagaaggat
     7321 caagttagaa ggatacatga tttagttaaa tatgctattt ggtctttaga agattctgct
     7381 gacagtaaag ataaagagtt taaaataact ttggaagcta atagttatat tgaagtagct
     7441 gactatttag aagataataa agtagatagt ggagtttatt ttttagatat cgagcttagt
     7501 agggataaag cagatagaga tggaatagac ttagctgaat ttattagaca aagagatcca
     7561 aatgcacaga taatttttat tacagcttat gaaaatctag cagcaatgac ctatagacgt
     7621 cgcacaggag cgttagattt tattactaaa aatgatagtg atgaagtgat tcaaaagcga
     7681 ctaaatgaga ctttatcatt agctgcaagg agaattaggg aatctcatgc cataaagaaa
     7741 atgacattta gctataaaat gggcagaaga attattaacg aaaatattaa tgatattcta
     7801 tatattatta ccactcctaa gtcacataga ttagaaatag ttacagttaa tggtatgggt
     7861 gagtttacag gcgatattaa gaagttagag gcagaaaatg attttctaga aaaaatatca
     7921 caatcttgtt tagctaatcc aagtaatatt gttgaaatta atctgtcaac aagggttatt
     7981 tcttttaaag atggatataa agagactttt cctagaagaa gtaaggctaa aatgaaaagt
     8041 ttgattgaaa ggtataattt gaaaacagtt taatcttttg tttttattga tataggtggt
     8101 gaaaatgaca tggtagaaat aggtattatc atattactag ttgtagggtt tatggtaatt
     8161 tcaaggttga aagtaaattt tacaaaaaat agtagatatg caggcttttt attgttaata
     8221 ttactggatc taaatggact tatgcgaact cctatgttaa cagtaagagg tttaatctta
     8281 ttgggaacat tgatgatttt tgtgattatg ttgattaaag aaattagaca aaatagaaaa
     8341 tatagttaat aaagagggtt ggaacttagg gtattccaat cctctttata tgacattcat
     8401 gattatcttt gcaaatgatt attgactaat ctacatttta acaacacttt tagtatccaa
     8461 ataaatctaa aaaaagacca aatttgataa tttagacaca atgatttaag aatatgataa
     8521 attaaggcta ggaaatgaaa ttgtataatg gaaaaatcta gctgaaatta ttagtggaaa
     8581 tggggagtag tatatgaaaa taaataaaaa gttttataaa aattatactt tttatatcgg
     8641 tttagtaatg ttatcaatag cggtaggaag tatttttctt gataaaggat attttttatt
     8701 tacaattatt gacatattat ttacttgcct aggtataaaa tatgtctatc aatcattggt
     8761 gctaacaaag cgttatgaaa gaaatcgtta aaattaataa attaagaaag ctaggaaaaa
     8821 tcaaattaaa atttactcaa tgattttttt agctttttat tttaacaagt taaagaaaat
     8881 actaatacca aataagtata aaaaggacca gatttgatga tttaggcaag ataatttaag
     8941 aacatgatat gcttaataaa agagatgaaa gataataagt ttaatagggg gatattaact
     9001 tatgatacat aaatacaaaa aatattatat cccacaagta gacgagtctg attgtggcgt
     9061 agcttcgttg gctatgattt tgaaacacta tggatcatcg ctatcattag cgtatttaag
     9121 aaacattgct aagacaacaa tggaggggac tacagcttta ggtcttgtta agacagcaca
     9181 gactttagga atggaaacac aagccgtaaa agctgatatg tctctttttg gaatgaaaga
     9241 cattacatat ccatttattg tacatgtggt taaagaagag acgttattac attattatgt
     9301 agtattgaaa gcaacaccta attatatttt aattgctgat ccagctccag atgtagggat
     9361 aactaaaatg tcgtatgaac gttttgaaaa agaatggaca ggaattactt tattcatcgt
     9421 tccaggaatt gaatataagc cgacaaaaga gactagacaa tcattaatat cactatttag
     9481 taaattattt aagcaaaagc aactaatagt taatattgta ttggcagctt tgttaattac
     9541 aattattagt atattgggat catatttttt acagggaata attgatacat atattcctaa
     9601 tggtatgcat agtacactgg caattattgc ttttggatta ctagtaatat atgtgttcaa
     9661 ttcaattttt acatatgcaa gggatttttt attagcaatt ttaggacaac gactttcgat
     9721 tgaaattatt ttaagttata ttagacatat ttttgagttg cctatggaat tttttgcgac
     9781 cagaaaaact ggggaaatag tctctcgttt taatgatgct agtaaaatta tagatgcttt
     9841 agcaagcact gtagtatcta tttttttaga tgtaagcatt gtggttatta tgggaataat
     9901 cttggctatt caaaatctta aattattagg gataactctt atctcacttc caatttacac
     9961 gattattatt cttacattta caaaagcatt tgaaagattg aataataaac aaatggaaag
    10021 taatgcgata cttagttcat ctattattga agatattcaa ggaatagaaa caataaaagc
    10081 cttaaacagc gaacaaatgc gttatcgcaa aattgatagt caatttgtgg actatttgcg
    10141 taaatcgtta gcatatataa aaacagactc gttgcaacaa gcactaaagt tatttattca
    10201 acaaacatta aatgttatag tcctatggtt aggggcaaat ctggtaatta gtaatcaact
    10261 ctctatagga caattaatga cttttaacgc actattaagt tattttgtga atccgttaca
    10321 aaatatcata aatttacagc caaaattgca gagtgcaagg gtagctcaca atcgtttgaa
    10381 tgaggtttac ttagttgaaa gtgaatttaa agatagaaaa gctgttcatg atgtcactca
    10441 acttcaagga aatattatat ttcaagatgt tgactatcgc tatggatatg gtgaaaatat
    10501 tttggataag gttaatttga ctttaaaaca gggagaaaaa ctaactatag taggtatgag
    10561 tggctctggc aaatcaacgt tagttaaact attggtgaat ttttttgccc cagtttcagg
    10621 tagtataaaa ctaaataatc atgatataaa taacattgat aagcatactc tgcgttctta
    10681 tattaattac ataccacaga atccatatat ttttgctggg acaatagaag ataatcttag
    10741 actaggtaat cgatctaatg taactgatga ggatattctc atggcttgta aaatagcaat
    10801 gattgataca gatatagcga agatgccact acaattgaaa actaaactag atgaaaatgc
    10861 taatatctta tcaggtggac aaaaacaaag aattacaatt gctagagcct tattatctcc
    10921 agcacaagta ttaatttttg atgaatctac aagtggatta gatgccatta cggagaaaaa
    10981 actaattgat aatttaatga aattaaagtc aaaaactata atttttatcg cacatagatt
    11041 atctatagct aagcgaacaa ataatattct agtattagat ggcggaaaaa ttgtagaaaa
    11101 gggtagacat gatgaattat tagctaaaaa aggatattac tacaatttaa ttaatagtta
    11161 gggggagtat tgtattatgg aagataaatt tttagaaagt agcgaatttt attcagctag
    11221 atttagaaac ttttcaacta tgattattat tccttttaca attttattgt tggcggtagt
    11281 aatttttagc ttttttggaa aaaaggagat aactatccaa ggtgcaggaa cgcttgaggc
    11341 attgggaaat aatcctgtta ttcaatcaac tgtaaatagt cctattgaaa aaattattta
    11401 aaagaaggaa agtatgtaaa aaaaggagat acattacttg tttataataa tgtgaatata
    11461 caagataagg ggaaactgta taattcacaa aaagaaatct tagatagaca gttggcagct
    11521 ttgaacttac ttaaacaagg tgttcaagac aatcatgatt cttttgggga agatgatgaa
    11581 tttggttacc gtaatgattt aaagagttac ctacaacaaa ggaatacgta tttaacagaa
    11641 aatacaatga tccaggataa atctaaaaac gataaagcca aacaaagttc gattaataac
    11701 gagttgaaga aacaaggtgg gtctgctaca agtatagctg attttgattc gtctaaatac
    11761 gatattgata taaacaatca aaaaatgagt gatttacagt caagtaagtt aagttctatt
    11821 gatcaagaaa ttataaaaat caagcaaaat atatcagaat tgaacgctaa tattgatgaa
    11881 aataataata ctaatagaga gtataaggta aaggctgtta gagacggaat tttacatatt
    11941 aacgatgagt atagtgaaag tcattatata agtgcagggg ctaatttagc tcagatactg
    12001 ccgattttga agaatcaaaa aactttaaag ataaaggcat atataagtac agcagatatt
    12061 tcttccataa aagtagggca aaaagtaaga ttcaaagtaa ctagaaatgt acctaaacct
    12121 attattttga ctggaaaaat acataagata tcgatttctc cagtagagat agggaaagaa
    12181 aattattatc aaattgaagc taaaacagat attcaaaata ccaataggga tttattgaag
    12241 tatggtatgc aagggcaaat ggttgtaatt acaggtaaga caacattttt tgaatattat
    12301 aaggataagt tgtttaatag atagattaat ttgtacgcct ttactggata aaatatttgt
    12361 gagagctgga atatcttcag ctctttttaa gatgagggtg gagataattt aaattttgaa
    12421 atattagatt ttttcttttt atcaatagga attataatat tttttagtat atatcaattc
    12481 aaaaaaatta atgtagttgc attaatgaat atagcaacat cacattatac aaaggaagtt
    12541 attatcatgg aaagtatttg gttttattct taatattatt ggtagaggta atgttgataa
    12601 ataaaaagtt catggtagta gatactgatg ggattttttt gatgggtgtt gtttttaagc
    12661 aatagttaat ataattcgta tttagctaat tttatattta gtattagctg tttttactat
    12721 atgattagct aatttgtggt ataattaatt tgtggaggtg gtttaaatga cacaagttac
    12781 agcaactgaa ttaaagaata atctcggtaa gtatttaaaa aagtcagaat ttgaagatat
    12841 atacattact aaaaatggag taattgtatc agttttatct aatccaaatc aaagtaaact
    12901 gcaaatgtta gatgacttaa aaggaattgc accagatatg aatatgacag atgaggaact
    12961 aagaagtgaa aggattagta atatctgatg aaaaaagttt tagttgatac gtgtgttatt
    13021 attgatattc ttttggatag agaaaaattt gttgatgata gttatagcgc tgtttctaag
    13081 ttaataagga agggcgatac tatttgtacg acagctaagg caatgacaga tattttttat
    13141 attgtacatc attcattaca cgataatgat aaaactaaag aagtcttgtt aaagttaagt
    13201 agagtctatc agatccttga taccaaagaa aaagatacca taatggcaat cacttctgac
    13261 gtagctgatt atgaggacgc tgttatggtt gaaacggcca tcgctaacaa ggtggatttt
    13321 attttaacga gaaatattaa agattataag aaagctaaaa taaaagtgat tagtccaaca
    13381 gagcttaatt aaatttatcc taaaaagaaa tgcagaatct ccttttaaat gaagagattt
    13441 tttattgtct ataagtaacc gttttactat ctaacagtta tctaacttat cattataaag
    13501 ataacttcca gagtttctct ctaaagaaac gttttctgca agttactttt taatttttcg
    13561 ctatctagta tagcatatcg ggtatatagt tgtctttgtc acttctttgt aggagtggca
    13621 ttttttagat tttaattgat taaatttgtg ttacaaaaag taatactatt ttgttatact
    13681 tattgtatat ttagtactgt ttaatgtttt gaagaaagga gggcaattaa aaaactatgt
    13741 ttagatcctc tagtgagaaa tttaagctct attattatgt gtcctcgttg tttccgatac
    13801 atatctcagt attagtattt atattttctt ctaaactaga aaataacaat tgtgagaatt
    13861 tgtttaaagt gtcatctacc tcgtcaaaaa ttacaatatt aataatgttg ttgtcaatat
    13921 tagtagattt atattcgtta gttcgtgtta ttcagttatt gaataaccaa aagaaattaa
    13981 ctaaagcatt aggtactaat agtgttagaa tttctaatga atataatggt ggattaaggg
    14041 attttctgct tagttttatt gtacctgcaa taacaacatt ttcagctgat gagaatccat
    14101 taactatgat tatatttatt ttactttttc aatttatcgt atatgtattt tacaaaaatt
    14161 cttccgactt ttttccaaat atttcattaa tgtttatggg atattctgtt tttaaagttg
    14221 atacatatga tttgggaggt atagagtatg tttttggaaa gacaaaaaat attgatgata
    14281 ttattttaaa aaaagtagat gtgattatga taggtgataa aaactaccct aataatgtag
    14341 caattattct tgaaaaaaag gtgtgattac atgaacataa ataaaatatt tttgctaaat
    14401 ttcaacgata caaatgactt taatataaag caagttgcga tagaaaatga caaagtagtt
    14461 tctttttcta aatcaattaa gaatatttca gaatatggaa tgaagaacta ttttgattta
    14521 gctgaatctt tagagaatcc taaaaaatat tctataagtt taggcgaaaa tgatgaaaaa
    14581 acatatcata ttgacttatt agaaaaaata aggtcttgaa gtgccttaca attgttagac
    14641 aaagtctagc gattgtgagg tgcttttttc atatgactaa atatactcaa aaattcaaat
    14701 tagatcttat tcaagaatac ttagatactg gctgttcaca acgatgtcta gaaaataagt
    14761 attctttacc aaaggatacc ttaaaaaaat ggtggactgt atacaattta aaaggacccg
    14821 aagggttgaa attacgacat ttcaaacgta aatttactgt tgattttaaa cttcgtgtga
    14881 taaactacta cctaaataat gatgtttcaa tgtccaaagt ggcggcttcc cataatcttt
    14941 tgtgttcaca gatatctatc tggttgaagt tgtttatgga aggtggatct gaggccttga
    15001 aacccaagaa gaaaggtagg ccaagtaaga tgtcaaaaat gacaaagaag gatgcacgta
    15061 aaattttaaa aaaggaaagt gatgaaattg cggcactaaa gagtgaatta cgtcaagtca
    15121 aaatggagcg tgatatctta aaaaaatcgt tgaccctgtt cgg
//
