LOCUS       gnlProkkaOBCJLMGD_103   9039 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OBCJLMGD_103.
ACCESSION   gnlProkkaOBCJLMGD_103
VERSION     gnlProkkaOBCJLMGD_103
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 19:20:55
            Original ID  :: gnl|Prokka|OBCJLMGD_103
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9039
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9039
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1559:9038]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1560..9038
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9039
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9039
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             518..1042
                     /locus_tag="ctg90_1"
                     /transl_table=11
                     /translation="MSEQQKYWFAARTRDKQEFAIRDSLEKLKTELDLNYYLPTQFVIR
                     QLKYRRKRVEVPVIKNLIFIQATKQDACDISNKYNIQLFYMKDLLTRAMLIVPDKQMQD
                     FIFVMDLDPNGVSFDNDHLSVGSRVQVVKGDFCGVEGELASEANKTYVVIRIAGVLSAS
                     VKVPKSYLRVI"
     CDS             1046..1528
                     /locus_tag="ctg90_2"
                     /transl_table=11
                     /translation="MNTLTSQIEQLQSLAHELLYLGVDGAPIYTDHFRQLNKEVLEQSD
                     ALYPQRGATPEEEANICLALLMGYNATIYNQGDKEEKKQVVLNRCWDVLDQLPATLLKC
                     QLLTYCYGEVFEEELAKEAHTIIESWKDKELSEDKKEAINNLRNLEENPYPYSEME"
     CDS             1560..2453
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 268.8; E-value:
                     9.4e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.1e-14, bitscore:
                     41.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAG
                     IREILIISTPYDLPGFQRLLGDGSDFGVHFEYAEQPSPDGLAQAFIIGEKFIGSDSVCL
                     VLGDNIFYGQGFTRMLREAVHSAESENKATVFGYWVSDPERYGVAEFDQEGNVLSIEEK
                     PQIPKSHYAVVGLYFYPNKVVEIAQNIKPSPRGELEITTVNQQFLLDQELKVKLLGRGF
                     AWLDTGTHDSLSEASTFIEVIEKRQGLKVACLEGIAFRQGWISSEKMKVLAQPMLKSQY
                     GQYMLKMIDITTSNEE"
     CDS             2626..3930
                     /locus_tag="ctg90_4"
                     /transl_table=11
                     /translation="MIYMFTRMIRSLLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTA
                     AIYEGEILWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVAL
                     LGFALLPVPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKT
                     LGQFVMDNLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKD
                     RRKFLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFV
                     LVLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMG
                     YIPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRT
                     ALFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             3944..4642
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_5"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             4662..5963
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_6"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-13,
                     bitscore: 39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 8.3e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 4.1e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             5975..7111
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_7"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.4e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             7108..8232
                     /NRPS_PKS="Domain: Aminotran_5 (30-292). E-value: 1.7e-33.
                     Score: 107.9. Matches aSDomain:
                     nrpspksdomains_ctg90_8_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 78.9; E-value:
                     5.8e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_8"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-31, bitscore:
                     98.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIVGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYECGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAISFLKISFKNIV"
     aSDomain        7198..7983
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg90_8_Aminotran_5.1"
                     /evalue="1.70E-33"
                     /label="ctg90_8_Aminotran_5.1"
                     /locus_tag="ctg90_8"
                     /protein_end="292"
                     /protein_start="30"
                     /score="107.9"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIVGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAI"
     CDS             8235..9038
                     /NRPS_PKS="Domain: Aminotran_1_2 (37-163). E-value:
                     5.5e-07. Score: 20.8. Matches aSDomain:
                     nrpspksdomains_ctg90_9_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     231.8; E-value: 2.2e-70)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg90_9"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.9e-80,
                     bitscore: 260.0, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.9e-08, bitscore:
                     20.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEENQITVTSPLLPSLDDFLPYLEDIWKRKWITNNGYYHQELEKA
                     LCQYLKVPYISLFTNGTLPLICSLQALRITGEVITTPYSFVATTHALWWNGIKPVFVDI
                     DPKTCNIDPNKIEAAITPKTTAIMPVHVYGNPCDFIAIQDIADKYGLKVIYDAAHAFGV
                     EVDGKSLLEFGDMSTLSFHATKVYNTIEGGALVCHDRQIKERVDFLKNFGFAGETQIVA
                     PGINGKIDEIRSAYGLLNLKAVDSAIEYRHQISKRYREGLGGIDGI"
     aSDomain        8346..8723
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg90_9_Aminotran_1_2.1"
                     /evalue="5.50E-07"
                     /label="ctg90_9_Aminotran_1_2.1"
                     /locus_tag="ctg90_9"
                     /protein_end="163"
                     /protein_start="37"
                     /score="20.8"
                     /tool="antismash"
                     /translation="YHQELEKALCQYLKVPYISLFTNGTLPLICSLQALRITGEVITTP
                     YSFVATTHALWWNGIKPVFVDIDPKTCNIDPNKIEAAITPKTTAIMPVHVYGNPCDFIA
                     IQDIADKYGLKVIYDAAHAFGV"
ORIGIN
        1 ataactactt tttttcttcc ataatgttag ttattaaatg aatttatgaa aggacaaagt
       61 ttgtataaaa aaatataaat ataaaagaat accggagttt ttttagttta aagggaaaat
      121 cttgaagtgt aaggatcttg ttattagtta tttatcttaa gatataggtg ttgtttcaaa
      181 aaacgttcgt cttttgaaac agcatttttt gagttttttt cgatgaaaaa atgaatattg
      241 taaagttgct gagcagagaa ctttttttgc tctatatgtg tttgaaaatc aacaatataa
      301 aatctttgat aaaattttat ccactaaata ttttgtacat taaaacagac tccttacctt
      361 tgttcaatca aacgaacgtt ttttgaaaca cattcgttcg ttctcaactt ctaaaaatgt
      421 ttcgtaaaat ttgacggttt gaaagagaaa agatgtctcg ttcaaaccgc gaagcgcacc
      481 cgaaataaag gaaaatttcc ccaagtataa atcgtaaatg tctgaacaac agaagtattg
      541 gtttgccgcc cgtacccgag ataaacaaga gtttgctatt cgtgactctc ttgaaaaatt
      601 gaagactgaa cttgatctca attactatct tcccactcag tttgtcatcc ggcagttgaa
      661 atatcgtcga aaacgggtgg aagtccctgt tattaagaat cttatcttca tccaagctac
      721 caagcaagat gcttgtgata tttctaataa atacaatatc cagctttttt atatgaaaga
      781 cctgcttacc agggctatgc tgatagttcc tgataaacag atgcaggact tcatatttgt
      841 catggattta gatccgaatg gcgtcagttt cgataatgac catttatctg tcggtagcag
      901 ggttcaggta gttaaaggtg atttctgtgg tgtcgagggc gaacttgcca gcgaggccaa
      961 caaaacttat gttgttattc gtattgccgg tgtattgagc gccagcgtca aagttcctaa
     1021 aagttattta cgtgtcattt aagttatgaa tacactcact tctcaaattg aacaattaca
     1081 gagtctcgcg cacgagttac tctatttagg tgtggatggt gctcctattt ataccgatca
     1141 tttccgtcag ttgaacaaag aagttttaga acaatccgat gcgttgtatc ctcagcgtgg
     1201 tgctactccc gaagaggaag caaacatctg tctggcatta ttgatgggtt acaatgcaac
     1261 catctataat cagggtgaca aggaggagaa aaagcaagtt gttctcaatc gttgttggga
     1321 cgtgcttgac caacttcctg ctactttatt gaaatgccag ttgttgactt attgttatgg
     1381 tgaggtgttt gaagaggagt tggcgaaaga ggcgcatact atcatagaaa gttggaaaga
     1441 taaagaactt tctgaagata aaaaagaggc aatcaataat ttgagaaatt tggaagagaa
     1501 tccatatcct tatagtgaaa tggaatagaa taattctatt ttttttattt atttgactta
     1561 tgaaaggcat tgttttagct gggggatctg gtacacgttt atatcctatt actaaaggag
     1621 taagcaaaca acttcttcca attttcgata aacccatgat ttattacccc atctctgtac
     1681 ttatgttagc tgggatacga gaaatactaa ttatctctac tccttatgac ttaccgggtt
     1741 ttcaacgttt actgggcgat ggttctgatt ttggagtaca ctttgagtat gcagagcagc
     1801 cttctcctga tggtttagca caagcattta ttattggaga gaagtttatt ggaagtgatt
     1861 ctgtttgttt agttttagga gataatattt tttatgggca aggttttacg cgcatgttgc
     1921 gtgaagcggt tcattctgct gaatcagaaa acaaagcaac cgtttttggt tattgggtaa
     1981 gtgatcctga acgttatggc gttgcagagt ttgatcagga gggaaatgta ctcagtattg
     2041 aagaaaagcc tcaaatacct aaatcacatt atgctgttgt aggactttat ttctatccta
     2101 ataaagtggt ggagatagcc caaaatatca aaccttcccc tcgtggagaa ttagaaataa
     2161 ctactgttaa tcaacagttt ttgttagatc aggaactgaa ggtcaaatta ttagggcgtg
     2221 gctttgcttg gttggataca ggtacgcatg actctctgtc cgaagcgagc acttttatcg
     2281 aagtgataga aaaacgtcaa gggctgaaag ttgcttgttt agagggaatt gcttttaggc
     2341 aaggttggat ttcttccgag aagatgaaag tattggcaca accgatgtta aagagccaat
     2401 atgggcaata tatgttgaag atgattgata taacgacctc taatgaggaa tagatgcctg
     2461 aattagatag taaaaaaatt aataatactg acttcttcaa atatagctaa tccttataat
     2521 tctttattta tggataaata gatttctgag tgttttttat ttagcgaata gaatattttt
     2581 acattcagcc ctgttaaatc gtaatttgaa ttgtcgttac attggatgat ttatatgttt
     2641 acacgaatga ttcgttccct tctttcccgt tctccccttt acgttttggc tctctatgcc
     2701 agcgttttga tttttctggt ttatacctgt gcctatgcct accgtaagcc atttaccgca
     2761 gccatttatg aaggtgagat tctttgggga ttcgatgtca aaatcctgta tgtcctttct
     2821 gagattatcg gctacgccct ttccaagttc atcggtgttc gtattctgcc ttcgatgaaa
     2881 gcgggtcacc gcatctatta tataataggg ctgcttactt tttccgaagt tgctttgttg
     2941 ggttttgcac ttcttccggt tcctttgaag gtgtgttcta tttttctgag cggtcttccc
     3001 ctgggtatga tctggggtgt catttttagc tatatcgaag ggcgtcgtat cagtgaaata
     3061 ttgaatgtcg ggctgagcgt tgctttgata gtctcttccg gtttggtgaa aaccttggga
     3121 caattcgtga tggataattt gcatgtgtcg gaatattgga tgccttttac caccggtttg
     3181 ttggtatacc ctgttatgtt gctttgcagc tggcttctca atcagattcc ggctcccaat
     3241 gagcaagata tcatacagcg taccaaacgt gctccgatgg atggtaaaga caggcgtaag
     3301 tttttgaggc aattcttttg gggaatctgc atgctggttg ttttttacgg tgccctgacc
     3361 gtgttccgtg agcttcgtga ctctttcgct gccgatattt ggaaggagct ccatattgag
     3421 ggtgcaatga tctttactca gacagaggtt cccattgccg tttttgtcct tgtactgatg
     3481 ttcctgattg tgtttgtccg taataatcgt ttggctctta atatcattta ttgcatcgcc
     3541 gtcacaggcg gttccttaat ggttttttcc acattgcttt atgtgtacgg ttttctttct
     3601 cctatttggt ggatgattct ttccggtctt ggtctgtata tggggtatat tcctttcact
     3661 tacctgatag aacgtctgat tgcttccctt agggtggtta gtacggctgt ttttattatt
     3721 tatttggccg attctttcgg ctatctgggc actacgggtg tgtttatggt caagaacttc
     3781 gtttctgctg acatttcctg gactgtcatg ctgatgcgta ctgccctttt ttcaggattt
     3841 gtttctgtcc tgtcgatttt tgcgatttac tgttatttca agcaacaatt gaattcactt
     3901 atattaattc cctctgaaat tcatgattaa aacagcaatg atcatggctg ccggtcttgg
     3961 tacccgcttc gggcattata ccgagcttgt gcccaaaggt tttgtggagg ttggtggaaa
     4021 acctatgatt atccgctcta tcgaaaccct tctttcctgc ggtatcgaac gtatcatcct
     4081 cggtacgggt tataaaaaag aggcttatga agcccttcag gcggatttcc cccagataga
     4141 gacctgtttc agtccccgtt atgccgatac taacagtatg tacactctgt acaatacgcg
     4201 tgacgtgata ggcgatgaca gtttcctgct gcttgaatcg gaccttgttt ttgaacgcaa
     4261 ggccatcctt tcgctactgg atgacgaatt cccggatgtg atgcttgtct cttctctgac
     4321 caagttccaa gatcagtatt atgtggaata tgaccgcaat cacatcctta cttcctgttc
     4381 ggtagacaag aacgcccttg aggcaaaagg cgagctggtc ggtatccata aactttccaa
     4441 tactttctac cgccggatgt gcgccgatta tgcgaccatc ctggagtccc agcctaaact
     4501 gggttacgag tacgaactgc tccgcatgtc ccgttccgtt tcccctgtcc gtgtgctcag
     4561 ggtggagggg cttaaatggt atgaaatcga tgatgaagcc gacctttcgt atgctgagga
     4621 gcacatcatc cgctattgtt aaaaacaaat cttttccata tatgaacaag aaaatctatg
     4681 tcggtatgac cgcggatatc atgcatccgg ggctgatcca tattattcat gaagctacta
     4741 aatacggtga tgtcatcgtc ggtctgctga cggacaaggc catcgccgaa cacaaacgcc
     4801 tcccttacct tacctatgat cagcgtaagg aggttgttga gaatatcaaa ggggtttgcg
     4861 aagttgttcc ccaggaggat tggagctatg ttccgaatct ggaaaaactc aagcctgact
     4921 atatcatcca cggtgacgac tggaaaacgg gtccgttgcg cgaggtgcgc gaacaggttt
     4981 ttgaggtgat gaacgcccag gggggcaagg taatcgagat cccttatacc cggggcatca
     5041 actcctcctc gctcgacaag gatatcaagg cgatcgggac tacccctgac gtacgtctta
     5101 agtccctccg ccgcctgatc caggccaagc ctgtggtccg tatcctggag gctcacgacg
     5161 gtctttgcgg tctgattatt gagaatcttg aagtccagaa gggtgataag cgcgaggtct
     5221 ttgacggcat gtggtccagc agcctgaccg actccacgag taagggtaaa ccggatattg
     5281 aagcggtcga ccttaccacc cgtttacagg acctgaacaa tatccttgaa tgtaccacca
     5341 agcctattat ttttgatgga gacacgggtg gcaagatcga acactttgtc tttactgtgc
     5401 gcactctgga acgtcatggc atttctgcgg taatcattga agataaagtc ggtctgaaga
     5461 agaattccct ttttggtact gacgctatcc agactcagga tagtatcgag ggtttctgcg
     5521 ataagatcag agcagggaag aatgcccagg tcaccggtga ctttatgatc attgcgcgta
     5581 tcgaaagcct tattgccggc aaacccatga gtgacgccct cgaacgtgct tatgcctatg
     5641 tacaggcggg tgcggacggc atcatgatcc acagcaagga taagtcgggg gaggatatcc
     5701 gtgagttctg ccggactttc cgcaaagaat acgcccatgt tcccattgtc gttgttccga
     5761 cgacttatga ccatgtgcac gaatccgaac ttcacgaatg gggtgccaac gtagtcattt
     5821 acgccaacca ccttctccgt gccgcttacc cggccatgat gaacgtggcc aggaccatcc
     5881 ttgaaaacga gcgcgccgag gaggtccgtc cgctttgtat gcctatcaag gaaattctgg
     5941 aattgattcc gggcactaaa taaatcagac ggttatggta agtgtagaaa agatatacga
     6001 tacgttcctt catcacggtg ttgacttctt tacgggtgtt cccgattccc ttttgaagaa
     6061 tatttgcgcc tatatcacgg atcatgctcc gcgtggtaag catatcatcg ccgccaatga
     6121 aggttccgcg gtgggcattg cctgcggtta ttatatggct tccggcaacg ttcctttggt
     6181 ttatatgcag aactccggtc tgggaaatac ggtgaatccc ctcttgtccc ttgcggacga
     6241 gaaagtgtac agccttcctc ttcttttgct ggtcggctgg cgcggtgagc ccggcacgaa
     6301 agacgaaccc cagcataaga agcagggcga ggttaccctt gatcttctga aagccatgaa
     6361 aattcctttt ataattctgg atacggatga agacgaggcc ctggcgcaga tccatgatgc
     6421 ggttgtctcg gcgaagagcc ggtcgattcc ccatgcgatt gtcatccgta aagatacgtt
     6481 tggaaaatat aaattgcgtc aggaagcctt gaatgactat cctctgtccc gtgaggaggc
     6541 gctaatgcag gttgtcgacc acctcgggga caatgacatt gtggtttcca ccacgggcaa
     6601 gctctcccgt gagcttttcg agtaccgtga atcgaaaggg caggggcacg caagggattt
     6661 cctaactgtg ggttccatgg gtcacagttc ttccattgcc ctggggattg cccttgagaa
     6721 gcctgaccgc cgtgtctact gtcttgacgg tgacggtgcc tttatcatgc acatgggtgc
     6781 tgtcagcaat atcggcgatc tttctcccaa gaattacagg cacgtccttt tcaacaacgg
     6841 tgcccatgaa tctgtcggcg gtcaacccac gctcggtttc cgtctggata tcgcctcgat
     6901 agcgaaaggt tgcggttatg cgcatgtact gactgcctcc gacaaggaag ggctttcgtg
     6961 tgcgcttgag aagctgtccg gcctgtccgg cccggttctt cttgaaatta aggtccggat
     7021 cgattcacgt gatgatctgg gtcgccctac gactactccg gtagagaata aagagcattt
     7081 tatggcattt ttaaaagata cgcattcatg aatatcgaaa gaaagatcct tttgaatccg
     7141 ggtcccgcca ccacgacgga tacggtgaag ctggcgcagg ttgttcccga tatctgtccg
     7201 cgtgagaaag agtttgcggg tatgatgaaa cagttacgtg acgacctggt ccgcgttgcg
     7261 catggagacc tctccaaaca tacggccgtc ctgttttgcg gctcggggac gatcaatatc
     7321 gatatctgcc tgaactctct tcttcctgcg gataagaaag ttctggttgt caataacggt
     7381 gcctacagca cccgtgcggt ggaagtctgc gaatattacg gtcttcccca tatcgatttg
     7441 aagttttccg tttacgaact tcccgacctg tcggtaatcg aaaagacgct ttccgacaat
     7501 ccggacatcg ctttggtcta taccacgcac catgaaacgg gtacgggtat cttgaacccc
     7561 atccgtgaga tcggaaaaat agcccattcg cacggtgccg tttttgttgt cgacaccact
     7621 tcttccctgg gtatgattcc ttttgatatc gggaaggata atgttgactt ttgtatggct
     7681 tcggctcaga aaggccttca ggccatgacg ggtctttcct ttatcgtagg tgatgaatcc
     7741 ctgatacgtg cttcaaggga ttatccgaaa cgttcctact attgtaacct ctatttacaa
     7801 tacgattact ttgagaagac gggtgagatg cattttactc ctcctgttca aaccgtttac
     7861 gctgcccgtc aggctcttga tgaatatttt gcagtaggtg aagaggctaa attcgcccgt
     7921 cacaagaggg tctttgaagc catccataaa ggtttgcaag agcttggtct tcagtatgcg
     7981 atcaaacgtg aatggcagtc gggtcttgtt gtttctgtat tgtatcctga tgatcccctc
     8041 tgggattttg ataaggttca tgattactgc tatgaatgtg gctttacgat ctacccgggt
     8101 aagatttcca caacgaatac attccggctt tgtgcgttgg gagagattga tgtggaggat
     8161 attgagaggt tctttgaggt gatgagggaa gcaatttcat ttctcaaaat cagttttaaa
     8221 aatatagttt aattatggaa gagaatcaaa taactgtaac ttcgccttta ttgccttctt
     8281 tagacgattt tttaccatat ttagaggata tatggaagcg taaatggatt accaataatg
     8341 ggtattatca tcaagaattg gagaaagctt tgtgccaata cttgaaagta ccatacatct
     8401 ctttgtttac aaatggtact ttgcctttaa tttgctcttt acaagctttg agaattactg
     8461 gtgaagttat aacaacacca tacagctttg tagcaacaac gcatgcttta tggtggaatg
     8521 gcattaagcc tgtgtttgtg gatattgatc ctaaaacttg caatattgat ccgaataaga
     8581 ttgaagcagc tattactcct aagacgacag ctattatgcc agttcatgtc tatggaaatc
     8641 cttgcgattt tattgctatc caggatattg cagataaata tggactaaaa gttatttatg
     8701 atgcggctca tgcttttgga gtagaggtag atggaaaatc tcttctagag tttggagata
     8761 tgtccacact aagttttcat gcaactaagg tttataatac aattgagggg ggagcattag
     8821 tttgtcatga ccggcagatt aaagagagag ttgatttttt gaagaatttt ggttttgctg
     8881 gtgaaactca aattgtggct cctggaatca atgggaaaat agacgagatt cgttctgcat
     8941 acggactact taatttaaaa gctgttgatt ctgctattga ataccgacat caaatatcta
     9001 aaagatatcg tgagggatta ggaggtattg atggtatta
//
