LOCUS       gnlProkkaNMJOLDJH_122  13981 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NMJOLDJH_122.
ACCESSION   gnlProkkaNMJOLDJH_122
VERSION     gnlProkkaNMJOLDJH_122
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 19:23:35
            Original ID  :: gnl|Prokka|NMJOLDJH_122
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13981
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13981
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1044:3474]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1045..3474
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..13981
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13981
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(147..1040)
                     /locus_tag="ctg103_1"
                     /transl_table=11
                     /translation="MQTENFTLGKKELLILLGLTLVLPFPINWALIELNPLTLMAGADD
                     VPTWIGFGGSYIGGIIGGVISIMILNKTLQQTGVLHYDLKLLQLDTIIYTQQQDWFTGF
                     KQELAENLKSIDLYVLNMVVSSISMKNYAYAKEVLTEINKGLEYQMVAASFSFTSTHLS
                     SEEKKYMNLVRRVQTEYSSFIKDILYYIPLAETISSRKKLNYDQLMDYTLSQYDYLQGQ
                     EGESTASGAIIPRVMEIDPSDDIRKELERIMEERLTGRTYLYHLKSDLAEATHQLIIYE
                     ENRINSILHKPEREMN"
     CDS             complement(1045..3474)
                     /NRPS_PKS="Domain: AMP-binding (12-401). E-value: 4.8e-83.
                     Score: 270.8. Matches aSDomain:
                     nrpspksdomains_ctg103_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (509-568). E-value: 2.7e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_ctg103_2_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     257.4; E-value: 3.6e-78)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_2"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-87, bitscore:
                     282.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.8e-11, bitscore:
                     32.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNIQENLSRSLSTWGDKPAVVAKDGTVSYQMLERYSANIAQSI
                     RQRLSVTDPSGLRNICIGVCMERNKILVPAILAIFRLGATYLPIDPSLPDNRKRYMAEN
                     ADMVLLLTDSSNEVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPNDCAYIIYTSGTTGNP
                     KGVRISYRNLDTFTRNLVDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLIL
                     AGEDERRDISLLDELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNR
                     LKQQPYRLMNVYGPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQITLGAT
                     GELCLGGPQVSLGYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVK
                     IRGFRIELTEIAERLNRDPDVERAHVVVVERNGRQLLGAYLQPSVSGNFHPEEVKERLR
                     AELPYYMIPNLWQVVDHFQRTINDKIDVRALPAFTSLELKYVPPVHPGEVILCGILKEM
                     LGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPINVSAVYTARNLRRLLLVPRQEP
                     IYWYRQQNLKKPVIILVCGSAYFNHLYFNLADRLYPKYDFLVVDAIYDHFNKVATDIPE
                     LLEYYVRTVQPMIRERTVYALTGFCMGAELAVGLAEMLHRSMGIMPKVFALDGQAWQNP
                     ALCQNYPLLVFPGDTDEMVRERNEIINIYFRTTPNLIYQGEVIVLLSGLFHQQAGLSPE
                     ESWTEENYRIFRTEYDNCERLWNKYYPNAPVLRLPADHWHFLEGESLEQLITVFLK"
     aSDomain        complement(1771..1947)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg103_2_PP-binding.1"
                     /evalue="2.70E-10"
                     /label="ctg103_2_PP-binding.1"
                     /locus_tag="ctg103_2"
                     /protein_end="568"
                     /protein_start="509"
                     /score="32.6"
                     /tool="antismash"
                     /translation="LCGILKEMLGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPI
                     NVSAVYTARNLRRL"
     aSModule        complement(1771..3438)
                     /complete
                     /domains="nrpspksdomains_ctg103_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg103_2_PP-binding.1"
                     /locus_tags="ctg103_2"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2245..2307)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg103_2_0004"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg103_2"
                     /protein_end="410"
                     /protein_start="389"
                     /score="36.2"
                     /tool="antismash"
                     /translation="FIGRKDTQVKIRGFRIELTEI"
     aSDomain        complement(2272..3438)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg103_2_AMP-binding.1"
                     /evalue="4.80E-83"
                     /label="ctg103_2_AMP-binding.1"
                     /locus_tag="ctg103_2"
                     /protein_end="401"
                     /protein_start="12"
                     /score="270.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LSTWGDKPAVVAKDGTVSYQMLERYSANIAQSIRQRLSVTDPSGL
                     RNICIGVCMERNKILVPAILAIFRLGATYLPIDPSLPDNRKRYMAENADMVLLLTDSSN
                     EVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPNDCAYIIYTSGTTGNPKGVRISYRNLDT
                     FTRNLVDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLILAGEDERRDISLL
                     DELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNRLKQQPYRLMNVY
                     GPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQITLGATGELCLGGPQVSL
                     GYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVKIR"
     CDS_motif       complement(2380..2466)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg103_2_0003"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg103_2"
                     /protein_end="365"
                     /protein_start="336"
                     /score="27.3"
                     /tool="antismash"
                     /translation="LGATGELCLGGPQVSLGYIGSVQLNEKSF"
     CDS_motif       complement(2968..3024)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg103_2_0002"
                     /evalue="1.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg103_2"
                     /protein_end="169"
                     /protein_start="150"
                     /score="26.8"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGNPKGVRIS"
     CDS_motif       complement(3205..3246)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg103_2_0001"
                     /evalue="3.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg103_2"
                     /protein_end="90"
                     /protein_start="76"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LAIFRLGATYLPID"
     CDS             complement(3487..5853)
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 170; E-value: 2e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg103_3"
                     /transl_table=11
                     /translation="MKRCLLYILCCFGVVQLSAQPADNIRNSFVKAETFYESGDIDEAC
                     RILEENLSSFQGTMHTEACRLAALCCLALDRFPEAEKYVSLLLKDEPYYYISLQDPERF
                     ADMVRKHRETKVTLVTASQQVETPEEAPVPVTLITEEMIRVIHARCLRDVLIAYVPGIS
                     GLSSNEEMNLAMRGVYSPEQENILIMQDGQRLNSYITNAVSPDYGISLAKVKQIEVLRG
                     PASSLYGSVALTAVINIVTKDGVDVRNGSVSVSAGNRGQLAADLLLGKHDMNMDFMAWF
                     SLYRATGESVFVPAEKQYALYPRDGFIRLDNYSGFPAMDGGIKLQRGNLLFSFSMNYAK
                     KRQPYSMWLFSSPYSYERFRTFDGSGPGYSRWSAREQAVYSRTWQRITFNTAFYTDWNK
                     NVHYETSGDTLQDYPIFPNYDYQPIIYPTRGTFQYIRWMDFNVGFNGRVNYAYDWGKLG
                     KGNMLGGVEWNRYTLYDSEYLEGMNFKEIVRTWIEKRLYTGHEMNTDAFLQIKHNLHQN
                     WIVNAGIRYDYKRRSNKRTLQAFSPRLSLIYLRNGLNIKASYSRAFVDAPYYYRNNEMD
                     TYSGGENLQAEYLSSYQVTCAYHHSPSHIDVECNLFYNRASHFLFTQPETRVYENAGSL
                     NMGGVEVVARYKADRLSLDGNLCFQKVLNYTNFFVTDGSVNNVPGFSMNLVANYFLLKK
                     KVQSWSAHLKLNCSSHCYTQVSVLEDGLNGDATNYTIRLPGYAVFSFTTRYKYKRVEGS
                     LGIENLFNNRYECGGATVPIRQKGRWISASILYNF"
     CDS             complement(5850..6686)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 141.1; E-value: 1e-42)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg103_4"
                     /transl_table=11
                     /translation="MEKNISQEKRIEELEARLKEQEKLGSLGLLSAGIAHEIQNPLNFV
                     INFSKLSGQLLADLADRVDEAKARIPEAELEDIKDILSGLRENVDKIKEHGDRAISIIR
                     GILLYSRGKEDEFMPTQIQKLTKEYVWLAYHAMRANYKNFNIAIREDYAKDIPSIRLIP
                     QDFSRAVLNVMNNACYAVWKKWQNAPEGYSPEIMVTLEKLDKRVVLSIRDNGEGMSPEV
                     KRKLFDSFFTTKPVGQGTGLGMAIVRDIIENKHHGKVLFDSVLHEYTCFRFIIPIA"
     CDS             complement(6709..9546)
                     /locus_tag="ctg103_5"
                     /transl_table=11
                     /translation="MKKIVFLIMCLCSVYANSQEGIPFFVNYPASVYQAHNRNFDVVCD
                     SCGNVYFANFEGILHYDYNRWETIYTPGFSRVTRLFRDSEGRIWVGGYNVFGRIERDGR
                     GCITLRTLLSDLDTNSLGELEDMAEIDKRIYLKATSGRYYTVQSDSILAPVQVLPAQLQ
                     EKWRNQSSVSMNRAFSLPGGETISINSAHGLIMDDSGKKERFSVTERNGLCSNAVSGIA
                     ADGRGNLWGATDNGVFHVFIPSLFSRYTSGEGLKGEVISAVSYKGMIYTGTLQGLYVLK
                     QNTFVPVQGISQACWQLCLSPQGELYAASGDGVYVIRDYNHSEKLTDMAAYSLTFIGHT
                     NLLMGTMDGIYQYSADEERIKKISDVEKVVRLEVKKDRSVWAKTLYGEIYLREEGKSSF
                     VLQDRESEEIMTEYTDNDGCHWQTNLKGKEVQVHHSQIDTEKFNQCLYAIRNYVVRVIY
                     IEEDRAAWFGGDFGLIRMDLEKARTFTPVVPRIYLREVCLNRDSVYWGGDLPEESGGAD
                     WQINSTVPRLGNDVRSIRFSFATDAPCFTGSNEYRYRLVGYDPEWSSWDSGTVKEYANL
                     SSGTYTFCVRARDIYGTESEMKQFRFSLLPPFYLQWYCLILYTVAFGMLLFVLFKWRMR
                     SLLKEKERLEALVGQRTKQLVQQKNEIEEKSLKLEKALKELGQAQDELVRQEKMATVGK
                     LTQGLIDRILNPLNYINNFSHLTSGLLKDLYQNLESVKELLDEDTYLDSVDVINMMRDN
                     LEKIEEHGSNTTRVLKAMEEILRDRNRQLEKTELIGLCRKDMELLSSYYQKEITAMHIA
                     VRTSLPDNPLFIDGNAEQLGKTIMSLLNNGMYAIAKKYGKKAYPAEIGLALESKDGQAV
                     IRLYDNGVGIEQSILDKIFDPFFTTKTTGEAAGIGLYLSKEIILNHHGQIAVRSEKDEL
                     TEFTITLPLWEEKSV"
     CDS             complement(9543..11144)
                     /locus_tag="ctg103_6"
                     /transl_table=11
                     /translation="MIKLNENIIRWIIAVPCILLTVCLVLYRAYRHSASDRERLALSLE
                     EFRDKEKKSVLIQRVSQQMEEIAYQQKDISEKRRQEAVAQTQKANRMQQQAELARERAL
                     AAQLEAEKAYRMADEQKNLAMERQLQAEQSKRVADTLAFLALGRSLGTLSVTQYRSGNM
                     ELASLLAYTAWWFTKRYDGDVYHPAVFNALSLSCRQDQLWFGHKGAVTGIKLLSGGEEK
                     ARAGRNPLPGLVTVGKYGEMIRWKSENGQTYTSELLLNDPCYDFRDVLLRSDSQMYALS
                     YCGQLISTDSAGIVTRFLPKGEYRQLISIASNLVLAVSTTGIYSFDCINHEIQPYFQPE
                     HSITCVGQMEGYLYVFFKNGTVALLSSDGTFLRFIDSLPENSVVTAFCPLTNERYAIGC
                     REGVILICDKNGNIRQKLIGHQAAVTAISRKGNKLFSSSYDCTLRLWDLRKGKTESAVI
                     VTSPGWIHTFCFHPDGTSVFIGDEQGRLYRVPVSPDHMATVVRQGLQRDFTREEWEYYI
                     GKQIPFESYYLKTYQP"
     CDS             complement(11141..11569)
                     /locus_tag="ctg103_7"
                     /transl_table=11
                     /translation="MTLLQFRPVDGRLDEILSMLMHSREVASHPSLSYAIRLVSEEIIV
                     NILNYAYPQQAEGYLTLCLWDEDGEITLEFIDGGIPFNPLDKADPDISLPLEQREIGGL
                     GIFLVREMMDDVAYTYVNKENRLTIKKKYLQPTDEPVS"
     CDS             complement(11584..11889)
                     /locus_tag="ctg103_8"
                     /transl_table=11
                     /translation="MEKYEIHFVGSVLDSNTSGDEQAKIVALIEQGHSVALDLSGCSYV
                     SSAGLRVMLYAFKLAKAKSRDVCLVGVSQEVKDVMHMTGFDKFFRFYQTLDELSQP"
     CDS             complement(11908..13077)
                     /gene_functions="other (smcogs) SMCOG1054:hypothetical
                     protein (Score: 219.1; E-value: 2.2e-66)"
                     /gene_kind="other"
                     /locus_tag="ctg103_9"
                     /transl_table=11
                     /translation="MAVKILSVDDELDLEVLLTQYFRRQIRKGEYEFAFAHNGLEALQK
                     LLETPDFDIILSDINMPEMDGLTLLAKVNELKNPAMKCIMVSAYGDMDNIRSAMNKGAF
                     DFATKPIDLDDLSRTIEKAIEQVRYIRESQQEHNQLESIKNDLAIAGEIQQTILPRSFP
                     PFPELTEVVDIYASMTPAKDVGGDFYDFFQIDDERIGLVIADVSGKGVPASLFMAVSRT
                     LLRATALRGVSSAECLTYANKLLCKESLDSMFVTVFYGIYHYKTGMMDYTNAGHNPPYL
                     LRGGRTVECLPVASNFVVGVFDDIEFESNTLTFGIGDTLLLYTDGVTEAFNDKREQFSE
                     SNLQDILASMHESSSAKEVVTSVLQSVKTFSGDYPQSDDITLLSLQRIK"
     CDS             13425..13979
                     /locus_tag="ctg103_10"
                     /transl_table=11
                     /translation="MLIILKQDDSCQVAQTTCTTNSLEIRYKDYSVLKKTLDLNTKSIN
                     SNSCIELIIYGTHGNEKEICKLTKPDIKDLSYFFKGKVCRLVLDACHSACHIPHFKEML
                     TDDGIILCHVGICQVNSIETKTGKDTYERWINGNKEGLKVWSDGIVPAIYTRKNNTLTY
                     YECSKFEVDINHPFTGTEFKTY"
ORIGIN
        1 ttttccgaat accggattat tttttctaaa actattccta tataaaagat aaatcaagtt
       61 taaagtaact tttcatccaa ataaaaacaa atataaattc atttttaata ctgaaataaa
      121 aaaataccat attatattaa tatatgtcaa ttcatttctc tctcaggttt atgcagaata
      181 gagtttatac ggttctcttc ataaataatt aattgatgcg tagcctctgc aagatctgac
      241 ttcaggtgat acaaataggt acgcccggtt aatctttctt ccattatccg ttctagttct
      301 ttccgtatat catcagatgg atcgatttcc ataacacgcg gtatgatggc tcccgaagct
      361 gtagactccc cttcctgacc ttgcaaataa tcatattggg acaaagtata gtccatcagc
      421 tgatcatagt ttagtttttt cctggaagat atcgtttctg ccaaaggaat atagtaaaga
      481 atatccttga taaaagagct atattcagtc tgtacgcggc gtaccagatt catatacttt
      541 ttttcttcgg atgataaatg cgtagaagtg aaagaaaagg atgcggcaac catctgatat
      601 tcaagccctt tattgatttc tgtcaacacc tctttggcat atgcatagtt tttcatggat
      661 atagacgaaa caaccatatt caacacatac aaatcaatag atttgagatt ctctgccagt
      721 tcttgtttga aaccggtaaa ccaatcttgt tgctgagtat aaattatggt atctaactgc
      781 aggagtttca aatcgtaatg aagtacacct gtctgctgaa gtgtcttgtt cagaatcata
      841 attgagatga cccctccgat gattcctcca atataactgc cgccgaaacc tatccaggtg
      901 ggcacatcgt ctgcacccgc catcagagtc aacggattca gttcgattaa tgcccaattg
      961 attggaaaag gcagtacaag agtcaagcca agtaaaataa gaagctcttt cttacctaaa
     1021 gtgaagtttt cagtctgcat aaatctactt caaaaacaca gttattaatt gttccaatga
     1081 ttccccttct aaaaagtgcc aatgatctgc cggcaatcgc aaaacaggag cgttcggata
     1141 atatttattc cataatcttt cgcaattgtc atattctgtc cggaatatac gatagttttc
     1201 ctccgtccac gactcttcag gagacaatcc cgcctgttga tggaacaatc cggacagcaa
     1261 aacaataacc tctccctgat aaatcagatt aggagtggtt cgaaaataaa tatttatgat
     1321 ttcgttccgt tcacgtacca tttcatctgt atctccggga aataccaaca aaggataatt
     1381 ttgacagaga gccggatttt gccaagcctg tccatccaga gcaaaaactt ttggcattat
     1441 ccccatggag cgatgtaaca tttcggccag gccgacagcc agttcagctc ccatacagaa
     1501 gccggtaagc gcatagacgg tacgctcccg gatcattggc tgaaccgtcc ggacataata
     1561 ttccaacagt tccggaatat ccgtagcaac tttattaaaa tgatcgtaga tagcatctac
     1621 aactagaaag tcatatttgg gataaaggcg gtcggccaaa ttaaagtaca aatgattaaa
     1681 ataggcagat ccacaaacca gaatgattac gggtttcttc aggttttgct gcctgtacca
     1741 atagataggt tcttgccgcg gaacgagcaa taatcggcgc agattacggg cagtataaac
     1801 tgcagatacg ttgatgggac atcctttttt attggcctcg gtaacaagcc tcaacatatc
     1861 cagcgaagtt aatcccagat catcaatcaa atcggcctca acactgactt gaggcaaacc
     1921 taacatttcc ttcaaaattc cacataagat aacctcgccc ggatgaacag gaggaacata
     1981 cttcaactcc aatgaagtaa aagccgggag cgcccggaca tcaatcttat catttatagt
     2041 acgctgaaaa tgatctacca cctgccataa attgggtatc atgtagtaag gaagttctgc
     2101 acgcaaacgc tctttgacct cttccggatg aaagttaccg gagactgagg gttgcaaata
     2161 agctcccaat aattgacgcc cattccgctc aacaactact acgtgggctc tctccacgtc
     2221 cggatctcta ttcaatcgtt ctgctatttc agtcaattcg atacgaaaac cacgtatctt
     2281 gacctgagta tcttttcgcc cgataaaccg tattgaaccg tccggttgct gctgtaccaa
     2341 gtcacctgtc ctgtacaacc gttctccatc gtacgagatg aatgattttt cattcagctg
     2401 aacactccca atatatccca gcgaaacctg aggtcctccc aagcaaagtt ctcctgtagc
     2461 cccaagagtt atctgttgga ggttttcaga caaaacataa cagacagttc ccttgagcgg
     2521 atagccaata tcgtcatacg atgtatcttt gcctacaatc cgtatggtac tgagtacggt
     2581 attctctgtc ggtccatata cattcatcaa ccggtaaggc tgctgtttca gcctgttaaa
     2641 taacttttca ccaatagcct ccgcaccaaa gagcagagtc ttaaaggatg gaaagtcaag
     2701 atcggcaaac atgcccagca acgaaggagg gaaaaaagca atattcacct tctcgcgcct
     2761 gatcagttcg tctagtaaag aaatatctct gcgttcgtcc tcaccggcca ggatcaatgt
     2821 tcctccgacc ggaatacaca tcatcagttc taatatggaa gcatcaaaac tgatactcgc
     2881 aaacgccaga tacctgtttg ccggatcaga caaatgatac aatttcttat ctaccagatt
     2941 cctcgtaaat gtatccagat tccgataact aatacgtaca cctttgggat tgcctgttgt
     3001 tccggaagta tatataatat aggcgcaatc attgggaaga acttcagtat agtcaccaac
     3061 aaccggttcg gatagttgct ccccattcag gtaaagttgg cggacggacg ggattccacc
     3121 tacttcattc gatgaatcgg tcaacaacaa aaccatatcc gcattttcag ccatataccg
     3181 tttacgatta tccggcagcg agggatctat cggtaaataa gttgccccta accggaaaat
     3241 agccagaatg gcaggtacta aaattttgtt tcgttccata caaactccga tacagatatt
     3301 ccgaagtccg gacggatcag ttaccgataa acgttgacgg atagattgtg ctatattggc
     3361 agagtaacgt tccagcattt gataagagac ggtaccgtct tttgcaacga ccgccggttt
     3421 gtcaccccag gtagagagtg atcgagaaag attttcttga atgtttgttt tcattattag
     3481 tttgatttag aaattataca atatactggc ggaaatccac cttcctttct ggcggatagg
     3541 aacagtcgct cctccgcatt catatcggtt attgaaaaga ttctcaatgc ccagactgcc
     3601 ttctaccctt ttatacttat atctggtagt gaaagaaaag acagcataac cgggcaaacg
     3661 gattgtgtaa ttcgtcgcat ctccattgag tccatcttcc aatacactta cctgagtgta
     3721 gcagtggcta ctgcaattca attttaaatg ggcagaccag ctctgtactt tctttttaag
     3781 taaaaagtag tttgctacaa gattcataga aaagccgggt acgttattca cagatccatc
     3841 ggtaacaaaa aaattggtat aattcaatac tttctgaaaa cacaggtttc catccaggct
     3901 cagtcggtct gccttataac gggcaacgac ctcgacacct cccatattca gagaaccggc
     3961 attttcataa acacgtgttt ccggctgtgt gaacaggaaa tgggacgccc gattataaaa
     4021 taaattacac tctacatcta tatgtgaagg tgaatgatga taagcacaag tcacctgata
     4081 tgaacttaga tattcagctt gcagattttc gccacccgaa taggtatcca tttcattgtt
     4141 tctgtaataa tagggcgcat cgacaaatgc tctggaataa ctggctttga tatttaatcc
     4201 gttcctgaga taaatcagtg acagacgggg agaaaaagcc tgtaatgtcc gcttattact
     4261 tcgccgttta tagtcatacc tgatgccggc attgacaatc caattttgat gcaggttgtg
     4321 tttaatctga agaaaggcat ccgtgttcat ctcgtgtccc gtgtaaagtc gtttttcgat
     4381 ccacgtcctg acgatctctt taaaattcat accttccaaa tactcggaat cataaagcgt
     4441 ataccgattc cattccacac cgccaagcat attgcctttc cccagcttcc cccaatcata
     4501 ggcatagttt acacgcccat taaagcctac gttaaaatcc atccaacgga tgtattgaaa
     4561 tgttccgcga gtcggataaa taataggctg ataatcatag ttaggaaaaa taggatagtc
     4621 ttgtaaagta tctcccgagg tttcataatg tacgttttta ttccaatcgg tataaaatgc
     4681 ggtattgaaa gtgatccgct gccacgtgcg gctataaaca gcctgttctc ttgccgacca
     4741 tctggaatat cccgggccgg aaccgtcaaa agtacgaaac cgctcataag aatatggaga
     4801 agaaaagagc cacatgctat aaggttgcct tttcttcgcg taattcatac tgaaactaaa
     4861 aagcaaattt ccacgttgca atttaattcc tccatccatg gcaggaaatc ccgaataatt
     4921 gtccagacgg atgaatccgt ccctagggta aagagcatat tgtttttcgg ccgggacaaa
     4981 aaccgattct cccgttgcac ggtacaagga gaaccatgcc ataaagtcca tgttcatgtc
     5041 gtgctttccc aatagcaggt cagcagccaa ctggccccga ttaccggcac tgacagatac
     5101 ggaaccatta cgaacatcca ccccgtcttt agtaactata ttaatcacgg ctgtcaaagc
     5161 cacactgcca taaagcgaag aagccggtcc gcgcagcacc tctatttgtt tgacttttgc
     5221 cagactaata ccataatccg gcgaaacagc attagtaata taactgttca gacgttgtcc
     5281 atcctgcata atcaatatgt tctcctgttc gggagaatat accccgcgca tagccagatt
     5341 catctcttca ttggaagaca aaccggatat accgggcaca taagctatca gtacatcccg
     5401 caggcaccgg gcatggataa cccgtatcat ctcctccgta attaaagtaa caggcaccgg
     5461 agcttcttcc ggggtctcta cctgttgtga ggctgtgacc agagttactt tagtctccct
     5521 gtgtttcctt accatatccg caaagcgttc cggatcttga agcgagatat aataataagg
     5581 ttcgtctttc aataacagcg aaacatactt ttccgcttcc gggaagcggt ctaaagctaa
     5641 acagcataat gcagccaaac ggcacgcctc ggtatgcatc gtaccttgaa aagacgacag
     5701 attctcctcc aagatacgac aagcttcatc gatatctccg ctctcataaa atgtttccgc
     5761 ctttacaaac gaattacgga tgttatccgc cggctgagct gacagttgca caaccccaaa
     5821 acagcaaagg atatatagca gacagcgttt catgcgatag gaatgataaa ccggaaacaa
     5881 gtatattcat gcaggaccga atcaaacaat acttttccat ggtgtttgtt ttctataata
     5941 tcacgaacga ttgccatacc aaggcctgtc ccctgcccca ccggttttgt tgtgaaaaaa
     6001 gagtcaaata gttttcgttt gacctccgga ctcatgccct ctccgttatc acgaatagaa
     6061 agtacaactc ttttatccaa cttttctaag gtcaccatta tctcggggga atatccttcg
     6121 ggagcattct gccatttttt ccatactgca tagcaggcat tattcatcac attcaagact
     6181 gcccgactga aatcctgcgg gatcagccgg atcgagggga tatctttagc ataatcttca
     6241 cggatagcaa tattgaaatt cttataattg gcccgcatgg catgataagc cagccacaca
     6301 tattccttag tcaatttttg tatttgtgta ggcatgaatt cgtcttcttt ccccctggag
     6361 taaagcaaaa taccacgaat aatgctgata gcccgatcac catgctcttt gattttgtcc
     6421 acattctctc tcagcccgga aagtatatct ttgatatctt ccagttccgc ttccggaata
     6481 cgagcttttg cttcatccac cctatcggcc aggtcggcca acaattgacc ggacagttta
     6541 ctgaaattga tgacaaaatt caaaggattc tgtatctcgt gtgcaatgcc tgcactcaac
     6601 aagcccaatg atcccagctt ttcctgctct ttgagccgtg cttccaactc ttcaattcgt
     6661 ttctcttgtg aaatgttttt ttccataatc aatctgttct atgtttattt atactgactt
     6721 ttcctcccac aatggcagag tgatagtgaa ttctgtcaat tcatcttttt cagaacgtac
     6781 tgctatctgc ccatggtgat ttaatatgat ttccttactc agatacaaac cgatacctgc
     6841 tgcctctccg gttgttttgg tagtaaagaa cggatcgaag attttatcca gaatactctg
     6901 ctcgatcccc actccattgt catataggcg aatgactgcc tgtccgtcct tactttccaa
     6961 tgccaggcca atctctgccg gataggcttt cttaccgtat tttttggcta tggcatacat
     7021 accattgtta agaagactca taatggtttt tcccagttgt tcggcattcc cgtcaataaa
     7081 caacggatta tcgggcaagg aagtacgaac cgcaatgtgc atagccgtaa tctccttctg
     7141 ataataactg ctcaatagct ccatgtcttt ccggcataaa ccgattaatt ctgttttttc
     7201 cagttgcctg ttacggtctc tcaggatttc ttccatggcc ttcagtacac gagtggtgtt
     7261 acttccatgt tcctcaatct tttccagatt atctctcatc atgttgatga catctaccga
     7321 atccaagtag gtatcttcat ccaaaagttc ttttacactc tccagattct gatatagatc
     7381 cttcagtaat cctgaggtca ggtgggaaaa attattaatg taattcaacg gattcagaat
     7441 acggtcaatc aacccttgag tcagtttgcc tacagtagcc attttttctt gtcgaaccaa
     7501 ttcatcttgt gcctggccca gctccttcaa tgctttttcc aattttaagg acttttcctc
     7561 aatttcattt ttttgttgta ccaactgttt ggtacgttgg ccgacaaggg cctctaacct
     7621 ctccttctct ttcagcaaac tgcgcattct ccatttaaac aatacgaaca acagcatccc
     7681 aaaagcaacg gtatatagga tcagacaata ccattgcaaa taaaaaggag gcaataacga
     7741 aaagcggaat tgtttcattt cactctctgt accgtaaata tcacgggccc ggacacaaaa
     7801 cgtatacgta cccgacgaaa ggttggcata ctctttcaca gtcccggaat cccacgaact
     7861 ccattccgga tcataaccga ccaggcgata tctatactca ttggaaccgg tgaaacaggg
     7921 cgcatcggta gcaaatgaaa aacgaatgga acgtacatca ttccccaaac gaggtactgt
     7981 actatttatc tgccagtccg ctcccccgga ctcttccggc aaatctcctc cccaatagac
     8041 agaatcacgg ttcagacaaa cttcacgaag atagatgcgg ggaacaaccg gagtaaatgt
     8101 ccgggccttt tcaaggtcca tccgaattaa accaaaatca ccgccaaacc atgccgccct
     8161 gtcttcttca atataaatca ccctcacgac ataattccga atggcataca ggcattggtt
     8221 gaatttctcc gtatcaattt gcgaatgatg tacctgtacc tcttttcctt tcagatttgt
     8281 ctgccaatga cagccatcgt tgtccgtata ctcggtcatt atttcttcac tctctctgtc
     8341 ttgaagtaca aaagagcttt tgccctcttc ccgcaaatag atttctccgt acaacgtttt
     8401 agcccataca gaacgatctt tcttcacttc cagacgaacg actttttcga catcggaaat
     8461 tttctttatc cgttcctcat ctgccgaata ttgataaatc ccatccatag tgcccatcag
     8521 aaggttcgta tgcccaatga atgtcaatga ataagctgcc atatctgtga gtttttccga
     8581 atgattataa tcccggatca catacacacc atcgccggac gctgcatata attctccttg
     8641 tggagaaaga cacagttgcc aacatgcttg cgaaattccc tgaacaggaa caaaagtgtt
     8701 ttgcttcaat acgtataatc cctgtaaggt cccggtatat atcattcctt tgtaagagac
     8761 agccgatatt acctctccct tcagaccttc accagaggta taacggctga acaaagaggg
     8821 aataaaaaca tgaaacacac cgttatccgt agctccccag aggttgccac gcccatcggc
     8881 cgcaataccc gaaacagcgt tactgcataa gccatttctc tcagttacgg aaaaccgttc
     8941 ttttttccca ctgtcatcca ttattaatcc atgggcagag tttatcgaga ttgtttctcc
     9001 tccgggtaga gaaaacgccc gattcattga gactgaggat tgatttctcc acttttcctg
     9061 caattgggcc ggaagtacct gaaccggtgc caaaatggaa tctgactgaa ccgtataata
     9121 tcttcctgat gtagctttca gataaatgcg tttatctatt tctgccatat cttccaattc
     9181 gcccaaagag tttgtgtcca gatcggaaag aagggttctc aacgtaatac atccgcgtcc
     9241 atcacgctct atccgtccga acacgttata tcctcccacc catatcctac cttccgaatc
     9301 acgaaacaaa cgggtgacac gggaaaaacc cggtgtataa atagtttccc aacggttata
     9361 gtcataatga aggatacctt cgaaattagc aaaatagaca tttccacaac tgtcgcaaac
     9421 gacatcgaaa ttacgattgt gcgcctgata aaccgaagcc ggatagttta caaaaaacgg
     9481 gataccttct tgtgaatttg catataccga gcaaagacac attatcaaaa agactatctt
     9541 tttcatggct gatacgtttt taggtaatag gattcaaatg gaatttgctt accgatataa
     9601 tactcccatt cttctcgagt aaaatcacgc tgtaacccct gacggacaac agtagccatg
     9661 tgatcgggtg aaacaggcac ccgatacaac cgcccctgtt cgtctcctat aaagacagat
     9721 gtaccgtccg gatgaaagca aaaagtatgg atccaaccgg ggcttgtcac aataacggcc
     9781 gactcggtct ttcctttacg aagatcccac agacgcagcg tacaatcgta actactcgaa
     9841 aacagtttgt tccctttccg ggaaatagca gtaaccgcag cctgatgccc tatcaacttc
     9901 tgccggatat ttccattctt atcacaaatc aggatgactc cttcacgaca gccaatggca
     9961 tatctttcat tggtaagagg acagaatgca gtaaccacac tattctcggg caagctgtct
    10021 ataaatctga gaaatgtacc atccgacgaa agtaaagcta ctgtcccatt cttaaaaaaa
    10081 acatagagat agccttccat ttgaccgaca caagttatcg aatgttccgg ctgaaaataa
    10141 ggttgtatct catggttgat acagtcaaaa gaataaatac cggttgtgga aactgccaat
    10201 accaagttag aggcaatcga aatcaattgc cgatattctc ctttaggcaa aaagcgggta
    10261 acgataccgg cggaatccgt ggagataagc tgcccgcagt atgacaaggc atacatctgt
    10321 gaatcggacc gcaacagcac atcccgaaaa tcataacagg gatcattcaa cagtaattcg
    10381 gaggtatagg tctgcccatt ttccgatttc caacgtatca tctcaccgta cttgccgaca
    10441 gtgaccaatc ccggcagagg attccgaccg gctcttgctt tttcctcgcc tccggataac
    10501 agtttgatcc cggtaacagc tcctttatgc ccgaaccaaa gctgatcttg cctacaagac
    10561 aaagacaatg cattgaaaac agccggatga tatacatcgc catcatatcg cttggtaaac
    10621 caccaggcgg tatatgccaa cagagaagct aattccatgt tgcccgaccg atattgagta
    10681 acagaaagtg tccccaatga acgtcccaaa gccagaaaag ccaatgtatc ggcaaccctc
    10741 ttcgactgtt cggcctgtag ttgccgttcc atcgccagat tcttttgttc atctgccatc
    10801 cgatacgctt tctcagcctc caattgtgca gcaagcgctc tttcccgtgc caactctgcc
    10861 tgctgttgca ttcggttggc cttttgagtt tgcgcaacgg cttcctgtct tctcttttcg
    10921 gaaatatcct tttgttgata agcaatctcc tccatttgtt gactgacccg ttgtataaga
    10981 accgatttct tttctttatc ccggaattcc tccagagaca gagcaagacg ctccctgtcc
    11041 gatgccgaat gacgatatgc ccggtatagg accagacata ctgtcaaaag tatacaagga
    11101 acggcaatga tccaacggat gatattttcg tttaacttga tcatgataca ggttcatcag
    11161 tgggttgcag atatttcttt ttaatggtca accgattctc cttattcacg tacgtatacg
    11221 ctacgtcatc catcatttca cgtaccagga aaatgcccaa tcctcctatt tcacgttgtt
    11281 ctaacggtaa tgaaatatca ggatcggctt tatccaaagg attgaatgga ataccaccat
    11341 ctataaactc caaagtaatc tctccgtctt catcccataa gcacagagtc agataacctt
    11401 ctgcctgctg cggataagcg taattgagaa tattgacaat gatctcctca ctgaccaaac
    11461 ggatggcata agacagggaa ggatgtgaag caacttcacg actatgcatc agcatactaa
    11521 gaatttcatc taacctccca tcgacagggc gaaactgaag taacgtcatt gctcaggtaa
    11581 tttttagggt tgtgataatt catcgagagt ctgataaaaa cgaaagaatt tatcgaatcc
    11641 ggtcatgtgc atcacgtctt taacctcttg tgacacaccg acaaggcaaa catctctact
    11701 tttagctttc gccagcttaa aggcataaag catgactctc aatccggcac tggatacata
    11761 agaacagccg ctgagatcta atgcaacaga atgtccttgc tcgataagag ctacaatttt
    11821 tgcttgttcg tcaccgcttg tatttgaatc caagacggaa cctacaaaat gaatttcata
    11881 cttttccatc gttcttttat tttaatatta tttgattcgt tgaagagaaa gcagggttat
    11941 gtcatcggac tgaggatagt ctccggagaa agtcttaaca gactgcaata cactcgtaac
    12001 aacctctttt gcggaactac tttcgtgcat agacgccaat atatcctgta agttactttc
    12061 cgagaattgt tcccgcttgt cgttaaaagc ctctgtgaca ccatccgtat acagaagtaa
    12121 agtgtcaccg atgccgaacg tcaatgtatt actctcaaat tcaatatcat cgaacacgcc
    12181 taccacaaaa ttagaagcga caggcaagca ttcaacagtc cgtccgccgc gaaggagata
    12241 agggggatta tgcccggcat tggtatagtc catcatgccg gttttataat gataaatccc
    12301 ataaaagacc gtaacaaaca tagagtccag gctctcttta cacagtaact tattggcata
    12361 agtaaggcat tctgccgacg aaacaccccg aagagcagtt gcacggagca gggtccgact
    12421 aaccgccatg aacaaggatg ccggcacccc tttcccagat acgtcagcaa tcaccagccc
    12481 gatacgttca tcgtcaatct ggaagaaatc ataaaaatcg ccacctacat cttttgccgg
    12541 agtcatggaa gcataaatat caaccacttc cgtcagttcc ggaaaaggag gaaaggaacg
    12601 gggaagaatc gtttgctgga tttctcccgc aatggccagg tcatttttga tagattccag
    12661 ttggttgtgc tcctgctgtg actcacggat atagcgaacc tgttcgatcg ccttttcaat
    12721 agtccgcgac agatcatcca aatcgatcgg tttggttgca aaatcaaacg ctcccttgtt
    12781 catagcagaa cgtatgttat ccatgtctcc ataagcagag accattatac acttcattgc
    12841 cggatttttc agttcattga ccttagccaa tagggtcaac ccatccatct ccggcatatt
    12901 aatatcactc aggatgatat cgaaatcggg agtttccaga agtttctgta aagcttccaa
    12961 cccgttatgg gcaaaagcga actcatattc accttttcgt atttgtcgcc tgaagtactg
    13021 ggtaagtaat acttctaaat cgagttcatc atctacactc aatattttta ctgccatatc
    13081 tattgttatt tatgaatttc aaccgtttgt tctgacgttt atgatggcaa aaatagagag
    13141 tgatcgaccc ggttacaatt ttatatttta aacaggaaga atgtttttcc gaatggacga
    13201 tattgtctta taagcataca ggtatattgc tttcgtggct tagaagacag cacttgaaag
    13261 attgatttac actcctgaaa gaaactattc cgtattcaga atttatattt ttaagatgga
    13321 acttttcttc tcacttttgt caccgtaagc ttacaaagaa taaatagaaa cggcggattc
    13381 cgaaaagccg aagaaagagt aggaactttt tacaaatcac tattatgctt attattttaa
    13441 aacaagatga tagttgtcaa gttgcacaaa cgacatgtac aacaaactct ttagaaatcc
    13501 gatacaaaga ttatagtgta ctgaaaaaaa ctctggattt gaacacaaaa tctattaata
    13561 gcaatagctg tatagagtta attatttacg gaacacacgg aaatgaaaag gaaatttgca
    13621 aactaaccaa accagacata aaagatctga gctatttctt caaaggaaaa gtttgtagat
    13681 tagttcttga tgcttgccat agcgcctgcc atattccaca tttcaaagag atgttaacag
    13741 atgatggaat catattatgt catgtaggta tctgccaagt aaacagcatc gaaactaaaa
    13801 caggtaaaga cacctatgaa cggtggataa atggcaataa ggaaggatta aaagtatggt
    13861 cggatggaat cgttccagct atctatactc gaaagaataa cactttaact tactacgaat
    13921 gtagcaaatt cgaagtagat attaatcacc cttttaccgg aactgaattt aagacttatt
    13981 g
//
