LOCUS       gnlProkkaCEKKKIHM_11   10412 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CEKKKIHM_11.
ACCESSION   gnlProkkaCEKKKIHM_11
VERSION     gnlProkkaCEKKKIHM_11
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 19:26:35
            Original ID  :: gnl|Prokka|CEKKKIHM_11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10412
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1125
                     /locus_tag="ctg6_1"
                     /transl_table=11
                     /translation="MYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALL
                     GFALLPVPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTL
                     GQFVMDNLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDR
                     RKFLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVL
                     VLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGY
                     IPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTA
                     LFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
     protocluster    1..10412
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1132:5412]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1133..5412
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10412
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10412
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             1133..1837
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.3e-15, bitscore:
                     47.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIER
                     IILGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLV
                     FERKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGI
                     HKLSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEAD
                     LSYAEEHIIRYC"
     CDS             1785..3158
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 213.9;
                     E-value: 4.6e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_3"
                     /sec_met_domain="CTP_transf_like (E-value: 2.1e-12,
                     bitscore: 37.4, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.6e-122, bitscore:
                     398.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 8e-65, bitscore:
                     208.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKPTFRMPRSTSSAIVKNKSFPYMNKKIYVGMTADIMHPGLIHI
                     IHEATKYGDVIVGLLTDKAIAEHKRLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNL
                     EKLKPDYIIHGDDWKTGPLREVREQVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIG
                     TTPDVRLKSLRRLIQAKPVVRILEAHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDS
                     TSKGKPDIEAVDLTTRLQDLNNILECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAV
                     IIEDKVGLKKNSLFGTDAIQTQDSIEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPM
                     SDALERAYAYVQAGADGIMIHSKDKSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHES
                     ELHEWGANVVIYANHLLRAAYPAMMNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             3170..4306
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 71.8;
                     E-value: 7.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.3e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6e-21, bitscore:
                     64.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGVALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             4303..5412
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 6.4e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg6_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_5"
                     /sec_met_domain="Aminotran_5 (E-value: 1.2e-31, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMKSVNTVLVNK"
     aSDomain        4393..5181
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_5_Aminotran_5.1"
                     /evalue="6.40E-34"
                     /label="ctg6_5_Aminotran_5.1"
                     /locus_tag="ctg6_5"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             5425..6243
                     /locus_tag="ctg6_6"
                     /transl_table=11
                     /translation="MLKKRLDYSQLKVIQLNILKDVDAFCRENNITYYLTYGTLLGAVR
                     HQGYIPWDDDIDIAMPRKDYEKFLSNYNLNGSKKNVYQVVAIELNNAYPYPFGKVQDLS
                     TVLLEYSDINYPLGINIDIFPIDGLPVDLKKSDKHFLKIKWLMMIMNLKKVKITIKRSF
                     LKNLILLIGKILTLLIPYRFIVRKMSYIAQRYDYEKSDYVSNLSCPDGKHERTSKRVFE
                     NSIEILFEGNNFYAPIGYHEWLHNIYGDYMKMPPVPERVSHHKFEIYKIL"
     CDS             6246..7241
                     /locus_tag="ctg6_7"
                     /transl_table=11
                     /translation="MCSKDNFLQEVRALCIFTVILLHVPFQGHDNISFNTWLMSKQLIT
                     FPVAVFFFLSGYFYSFRNYKSRIVKLLCPFLFWNMSVHLIKFIRGESGFNIENFLLGNG
                     LPYYYLAVLLQIVLFHYIIFKYWSEMVYRVLSISISIISLMAYYYFSISYSIHFNCYLY
                     FPFWILFYTLGTFGKKYWRNLISKIPFCVILLFILISVFLMFFEANLMYYILFQEGIAG
                     SQVKFSSWVYSILIVLLLLKIDYSIDENVTRNFGTLIGDYSYGVYLIHIFILSLIYKLC
                     IVVFNDNYNVLLPFIAASITLVISVFMIYILNKCLPPFILKFLGLYVKSN"
     CDS             7225..8397
                     /locus_tag="ctg6_8"
                     /transl_table=11
                     /translation="MLKVTDECTACGACLSICPKSCISFKSNEEGFLYPHIDIEKCVDC
                     DLCSKVCFLNDHITPTFRENDISYYAAKAIERCNLSSSGGIFPLLAESVLKNDGVVIGA
                     AWDDKFNVKHILIKSKSELPLLCGSKYIQSNTEKVFKIVKEHLSIQTVLFSGTPCQVKG
                     LKTFLGKDYDNLITVELVCHGVPSPLVFRRYLNGVLKYNNLDISQCSKINFREVKDDIY
                     RFVIYNKTKIPFYEQYTNLYTKTFLQNLFLRNSCYNCKCKLENSVGDFILGDFWGCRDF
                     YPEFYDPKGVSLVIVCTERAKKIWLNLKLSRIEVKKKIVFRSNRHLLKSASYNRNRDLF
                     FKTFIHEAEISLDDILMGYTNKDIWVKVKCLIISVLRFVGLFQLVQLYRK"
     CDS             8394..9452
                     /locus_tag="ctg6_9"
                     /transl_table=11
                     /translation="MKIALLTLPFVNNYGGILQAYALKHFLELRGHSVCIIDRNSNFKI
                     SFIDILRLAKRKFLGNRIRNFAYFKKQYLLPMTSEIITNKEMLLLDEKYQFDIYIVGSD
                     QVWRAIYYRDIKYNFYLDFVSSKRKISFAASFGISSWEYTNTETDIIAKLLMDFSFVSV
                     REDTAVRLCSDYLNINAVQFLDPTFLLDKNEYCCLADCFYSSKKIDIFAYIMGPDSSKD
                     KLIKIISDYSGLSVQSITQSKFSFKKNESIQEWLQNFYKSKFVVTDSFHGLAFSLIFNK
                     PFIVCGFSNRGMGRYESLLRYFSLENRLLYSLEDLKELNLSTIWDINWKEVNAKIAENK
                     RFVLELMQTVGV"
ORIGIN
        1 ctgtatgtcc tttctgagat tatcggctac gccctttcca agttcatcgg tgttcgtatt
       61 ctgccttcga tgaaagcggg tcaccgcatc tattatataa tagggctgct tactttttcc
      121 gaagttgctt tgttgggttt tgcacttctt ccggttcctt tgaaggtgtg ttctattttt
      181 ctgagcggtc ttcccctggg tatgatctgg ggtgtcattt ttagctatat cgaaggacgt
      241 cgtatcagtg aaatattgaa tgtcgggctg agcgttgctt tgatagtctc ttccggtttg
      301 gtgaaaacct tgggacaatt cgtgatggat aatttgcatg tgtcggaata ttggatgcct
      361 tttaccaccg gtttgttggt ataccctgtt atgttgcttt gcagctggct tctcaatcag
      421 attccggctc ccaatgagca agatatcata cagcgtacca aacgtgctcc gatggatggt
      481 aaagacaggc gtaaattttt gaggcaattc ttctggggaa tctgcatgct ggttgttttt
      541 tacggtgccc tgaccgtgtt ccgtgagctt cgtgactctt tcgctgccga tatttggaag
      601 gagctccata ttgaaggtgc aatgatcttt actcagacag aggttcccat tgccgttttt
      661 gtccttgtac tgatgttcct gattgtgttt gtccgtaata accgtttggc tcttaatatc
      721 atttattgca ttgccgttac aggcggttcc ttaatggttt tttccacatt gctttatgtg
      781 tacggttttc tttctcctat ttggtggatg attctttccg gtcttggtct gtatatgggg
      841 tatattcctt tcacttacct gatagaacgc ctgattgctt cccttagggt ggttagtacg
      901 gctgttttta ttatttattt ggccgattct ttcggctatc tgggcactac gggtgtgttt
      961 atggtcaaga acttcgtttc tgctgacatt tcttggactg tcatgctaat gcgtactgcc
     1021 cttttttcag gatttgtttc tgtcctgtcg atttttgcga tttactgtta tttcaagcaa
     1081 caattgaatt cacttatatt aattccctct gaaattcatg attaaaacag caatgatcat
     1141 ggctgccggt cttggtaccc gcttcgggca ttataccgag cttgtgccca aaggttttgt
     1201 ggaggttggt ggaaaaccta tgattatccg ctctatcgaa acccttcttt cctgcggtat
     1261 cgaacgtatc atcctcggta cgggttataa aaaagaggct tatgaagccc ttcaggcgga
     1321 tttcccccag atagagacct gtttcagtcc ccgttatgcc gatactaaca gtatgtacac
     1381 tctgtacaat acgcgtgacg tgataggcga tgacagtttc ctgctgcttg aatcggacct
     1441 tgtttttgaa cgcaaggcca tcctctcgct actggatgac gaattcccgg atgtgatgct
     1501 tgtctcttct ctgaccaagt tccaggatca gtattatgtg gaatatgacc gcaatcacat
     1561 ccttacttcc tgttcggtag acaagaacgc ccttgaggca aaaggcgagc tggtcggtat
     1621 ccataaactt tccaatactt tctaccgccg gatgtgcgcc gattatgcga ccatcctgga
     1681 gtcccagcct aaactgggtt acgagtacga actgctccgc atgtcccgtt ccgtttcccc
     1741 tgtccgtgtg ctcagggtgg agggtcttaa atggtatgaa atcgatgatg aagccgacct
     1801 ttcgtatgcc gaggagcaca tcatccgcta ttgttaaaaa caaatctttt ccatatatga
     1861 acaagaaaat ctatgtcggt atgaccgcgg atatcatgca tccggggctg atccatatta
     1921 ttcatgaagc tactaaatac ggtgatgtca tcgtcggtct gctgacggac aaggccatcg
     1981 ccgaacacaa acgcctccct taccttacct atgatcagcg taaggaggtt gttgagaata
     2041 tcaagggggt ttttgaggtt gttccccagg aggactggag ctatgttccg aatctggaaa
     2101 aactcaagcc tgactatatc atccacggcg acgactggaa aacgggcccg ttgcgcgagg
     2161 tgcgcgaaca ggtttttgag gtgatgaacg cccagggggg caaggtaatc gagatccctt
     2221 atacccgggg catcaactcc tcctcgctcg acaaggatat caaggcgatc gggactaccc
     2281 ctgacgtacg tcttaagtcc ctccgccgcc tgatccaggc caagcctgtg gtccgtatcc
     2341 tggaggctca cgacggtctt tgcggtctga ttattgagaa tcttgaagtc cagaagggtg
     2401 ataagcgcga ggtctttgac ggcatgtggt ccagcagcct gaccgactcc acgagtaagg
     2461 gtaaaccgga tattgaagcg gtcgacctta ccacccgttt acaggacctg aacaatatcc
     2521 ttgaatgtac caccaagcct attatttttg atggagacac gggtggcaag atcgaacact
     2581 ttgtctttac tgtgcgcact ctggaacgtc acggcatttc tgcggtaatc attgaagata
     2641 aagtcggtct gaagaagaat tccctttttg gtactgacgc tatccagact caggatagta
     2701 tcgagggttt ctgcgataag atcagagcag ggaagaatgc ccaggtcacc ggtgacttta
     2761 tgatcattgc gcgtatcgaa agccttattg ccggcaaacc catgagtgac gccctcgaac
     2821 gtgcttatgc ctatgtacag gcgggggcgg acggcatcat gatccacagc aaggataagt
     2881 cgggggagga tatccgtgag ttctgccgga ctttccgcaa agaatacgcc catgttccca
     2941 ttgtcgttgt tccgacgact tatgaccatg tgcacgaatc cgaacttcac gaatggggtg
     3001 ccaacgtagt catttacgcc aaccaccttc tccgtgccgc ttacccggcc atgatgaacg
     3061 tggccaggac catccttgaa aacgagcgcg ccgaggaggt ccgtccgctt tgtatgccta
     3121 tcaaggaaat tctggaattg attccgggca ctaaataaat cagacggtta tggtaagtgt
     3181 agaaaagata tacgatacgt tccttcatca cggtgttgac ttctttacgg gtgttcccga
     3241 ttcccttttg aagaatattt gcgcctatat cacggatcat gctccgcgtg gtaagcatat
     3301 catcgccgcc aatgaaggtt ccgcggtggg cattgcctgc ggttattata tggcttctgg
     3361 caacgttcct ttggtttata tgcagaactc cggtctggga aatacggtga atcccctctt
     3421 gtcccttgcg gacgagaaag tgtacagcct tcctcttctt ttgctggtcg gctggcgcgg
     3481 tgagcccggc acaaaagacg aaccccagca taagaagcag ggcgaggtta cccttgatct
     3541 tctgaaagcc atgaaaattc cttttataat tctggatacg gatgaagacg aggccctggc
     3601 gcagatccat gacgcggttg tctcggcgaa gagccggtcg attccccatg cgattgtcat
     3661 ccgtaaagat acgtttggaa aatataaatt gcgtcaggaa gccttgaatg actatcctct
     3721 gtcccgcgag gaggcgctaa tgcaggttgt cgaccacctc ggggacaatg acattgtggt
     3781 ttccaccacg ggcaagctct cccgtgagct tttcgagtac cgtgaatcga aagggcaggg
     3841 gcacgcaagg gatttcctaa ctgtgggttc catggggcac agttcttcca ttgccctggg
     3901 ggttgccctt gagaagcctg accgccgtgt ctactgtctt gacggtgacg gtgcctttat
     3961 catgcacatg ggtgctgtca gcaatatcgg cgatctttct cccaagaatt acaggcacgt
     4021 ccttttcaac aacggtgccc atgaatctgt cggcggtcaa cccacgctcg gtttccgtct
     4081 ggatatcgcc tcgatagcga aaggttgcgg ttatgcgcat gtactgactg cctccgacaa
     4141 ggaagggctt tcgtgtgcgc ttgagaagct gtccggcctg tccggtccgg ttcttcttga
     4201 aattaaggtc cggatcgatt cacgtgatga tctgggtcgc cctacgacta ctccggtaga
     4261 gaataaagag cattttatgg catttttaaa agatacgcat tcatgaatat cgaaagaaag
     4321 atccttttga atccgggtcc cgccaccacg acggatacgg tgaagctggc gcaggttgtt
     4381 cccgatatct gtccgcgtga gaaagagttt gcgggtatga tgaaacagtt acgtgacgac
     4441 ctggtccgcg ttgcgcatgg agacctctcc aaacatacgg ccgtcctgtt ttgcggctcc
     4501 ggtacgatca atatcgatat ctgcctgaac tctcttcttc ctgcggataa gaaagttctg
     4561 gttgtcaata acggtgccta cagcacccgt gcggtggaag tctgcgaata ttacggtctt
     4621 ccccatatcg atttgaagtt ttccgtttac gaacttcccg acctgtcggt aatcgaaaag
     4681 acgctttccg acaatccgga catcgctttg gtctatacca cgcaccatga aacgggtacg
     4741 ggtatcttga accccatccg tgagatcgga aaaatagccc attcgcacgg tgccgttttt
     4801 gttgtcgaca ccacttcctc cctgggtatg attccttttg atatcggaaa ggataatgtt
     4861 gacttttgta tggcttcggc tcagaaaggc cttcaggcca tgacggggct ttcctttatc
     4921 ataggtgatg aatccctgat acgtgcttca agggattatc cgaaacgctc ctactattgt
     4981 aacctctatt tacaatacga ttactttgag aagacgggtg agatgcattt tactcctcct
     5041 gttcaaaccg tttacgctgc ccgtcaggct cttgatgaat attttgcagt aggtgaagag
     5101 gctaaattcg cccgtcacaa gagggtcttt gaagccatcc ataaaggttt gcaagagctt
     5161 ggtcttcagt atgcgatcaa acgtgaatgg cagtcgggtc ttgttgtttc tgtattgtat
     5221 cctgatgatc ccctctggga ttttgataag gttcatgatt actgctatga acgtggcttt
     5281 acgatctacc cgggtaagat ttccacaacg aatacattcc ggctttgtgc gttgggagag
     5341 attgatgtgg aggatattga gaggttcttt gaggtgatga aaagcgtaaa tacggtatta
     5401 gttaataaat aatttagctc attcatgttg aaaaaaaggt tggactattc ccaattaaag
     5461 gttatacagt tgaatatatt aaaagatgta gatgcttttt gtcgtgaaaa taatataact
     5521 tattatttaa cttatgggac tttgttgggg gctgtaagac atcaaggata tattccttgg
     5581 gatgacgata ttgatattgc tatgccgagg aaagattatg aaaagttttt atcaaattat
     5641 aatctaaatg gaagtaaaaa aaatgtgtat caagttgttg ctatagagtt aaataatgct
     5701 tatccttatc cttttggaaa ggttcaagat ttatcaactg ttttattaga atattcagat
     5761 attaattatc cgttggggat aaatattgat attttcccta ttgatggatt acctgtagac
     5821 cttaaaaaat cagacaaaca ttttttgaag ataaagtggt taatgatgat aatgaatctt
     5881 aaaaaagtaa aaatcacaat aaaacgttct tttttgaaga acttaatatt attaataggg
     5941 aagattttga cacttttgat tccatatcga tttatagtgc gcaaaatgtc ttatattgca
     6001 cagaggtatg attatgagaa atctgattat gtttctaact tgtcttgtcc agatgggaaa
     6061 catgaacgga cgtctaaaag agtttttgaa aatagtatag agattttatt tgaaggtaat
     6121 aatttctatg ctcctatagg atatcatgaa tggcttcata atatttatgg agattatatg
     6181 aaaatgcctc cagttccgga aagagtatct catcataaat ttgaaattta taagatactg
     6241 taatcatgtg ttctaaggat aattttcttc aagaagttcg tgcattatgt atatttactg
     6301 taatattgtt acatgtacca tttcagggac atgataatat aagttttaat acttggctaa
     6361 tgtcaaagca gttgattact ttccctgttg ctgtgttctt ctttttatct ggatattttt
     6421 attcttttag aaattataag agtagaattg ttaaattgct ttgtcctttt ttattttgga
     6481 atatgagtgt acatctaatt aagtttatta gaggggaaag cggatttaat attgaaaatt
     6541 ttttattagg taatggatta ccttattatt atttagcagt acttcttcag attgtgttat
     6601 ttcattacat aatctttaaa tattggagcg aaatggtata tagagtattg tccataagta
     6661 ttagtattat aagtttgatg gcctattatt atttttccat ttcttattct atccatttta
     6721 attgttatct ctattttccc ttttggatat tattctatac tttaggaaca tttgggaaaa
     6781 aatattggcg taatttaata tctaaaatac ctttttgtgt aattctattg tttattttaa
     6841 tatctgtctt tttgatgttt tttgaagcta atttaatgta ttatattttg tttcaagagg
     6901 gaattgccgg ctctcaggtt aagttctctt cctgggtgta ttctatacta attgtgttgc
     6961 ttttacttaa aatagattat tcaatagacg aaaatgttac tcgaaatttt ggtacactta
     7021 taggtgacta ttcatatgga gtctatttaa ttcatatatt tatattatct ttaatttata
     7081 aattatgtat tgtcgttttt aatgataatt ataatgtatt attgcctttt atcgcagctt
     7141 ctataacatt ggttatttca gtttttatga tttatatttt aaataaatgt cttcctccct
     7201 ttatacttaa atttttagga ttgtatgtta aaagtaactg atgaatgtac ggcttgtgga
     7261 gcttgcttgt ctatatgtcc aaagagctgt atttctttta aaagtaatga agaaggtttt
     7321 ttatatccac atattgatat agaaaaatgt gtagattgcg atttgtgttc taaagtttgt
     7381 tttttaaatg atcatattac tccgactttt agggaaaatg atatcagtta ttatgcggct
     7441 aaggctattg aacgatgtaa tttgagctct tctggaggaa tattcccatt gcttgcagaa
     7501 tcagttttga agaatgacgg cgtagtaata ggagctgctt gggacgataa atttaatgtc
     7561 aaacatattc ttattaaatc aaaaagtgaa ctgccattat tatgtggttc aaaatacata
     7621 cagagtaata cagaaaaggt cttcaagata gttaaagaac atctgtctat tcaaactgtt
     7681 cttttctcag gaacaccttg tcaagtgaaa ggacttaaaa catttttggg aaaagattat
     7741 gataatttga ttacggtcga attggtttgt catggagttc cttcaccatt ggtttttaga
     7801 cggtatttga atggggtttt gaaatataat aatttagata tttcacagtg tagtaaaatt
     7861 aattttaggg aagtaaaaga tgatatctat agatttgtga tatataataa gaccaaaata
     7921 ccattttatg aacaatatac aaatctttat actaaaacat ttcttcaaaa tttattctta
     7981 cgtaattctt gttataactg taaatgtaaa ttggaaaatt ccgtaggaga ttttatctta
     8041 ggagactttt ggggatgtag ggatttctat cctgaatttt atgatccaaa aggagttagc
     8101 ttagttattg tttgtactga acgtgcaaaa aaaatatggt taaatttaaa attatcaaga
     8161 atagaagtta agaaaaagat tgtttttaga agtaataggc atttattaaa atctgcatct
     8221 tataatagaa atagagactt gttctttaaa acttttattc atgaggctga gatatcacta
     8281 gatgatattt tgatgggata cacaaataag gatatttggg ttaaggttaa atgtttgata
     8341 attagtgttt tacgttttgt ggggcttttc caattagttc aattgtatag aaaatgaaaa
     8401 tagcattact tactttacca tttgttaata attatggagg aatattacaa gcttatgctt
     8461 taaaacattt tttagagtta agagggcata gtgtttgcat tatagataga aattcaaatt
     8521 ttaaaataag ttttattgat atattacgtc ttgcaaaaag gaagtttctg ggaaatagaa
     8581 ttcgtaactt tgcttatttt aagaagcaat atttattacc aatgacatct gagattataa
     8641 ctaataaaga aatgttattg cttgatgaaa aatatcaatt tgatatttat attgttggta
     8701 gtgaccaggt ttggagagca atatattata gagatattaa atataatttt tatttggatt
     8761 ttgtgtcgag taagaggaag atatcctttg ccgcttcttt tggcatatct tcttgggaat
     8821 atacaaacac tgaaactgat attattgcaa aactgttaat ggatttttct tttgtttctg
     8881 ttagagaaga tacagcagta aggttatgtt ctgattactt gaatattaat gctgtgcaat
     8941 tcctagatcc aactttctta ttggataaaa acgaatattg ttgtcttgct gattgttttt
     9001 atagttctaa aaagattgat atttttgctt atataatggg gcctgattca tctaaagata
     9061 aattaattaa aataataagc gattattctg gcttgagtgt tcaatctata actcaaagta
     9121 aattctcttt taaaaagaat gaaagtattc aagaatggct acaaaatttt tataagtcga
     9181 aatttgttgt aacagactct tttcatggtt tagctttttc tttaatattt aataaacctt
     9241 ttattgtttg tggctttagt aatagaggaa tggggagata tgaatcttta ttgagatatt
     9301 tctctttgga aaatagactt ttatattcat tggaagattt aaaagaacta aatttatcta
     9361 ctatttggga tataaattgg aaggaagtta atgctaaaat tgctgagaat aaaaggtttg
     9421 tattggagtt aatgcagacg gtaggtgtat aatgtcactt aaagaaaata caatttatgg
     9481 tgtactgtgg agttcatttg agaaatttgg aactttatcg atacaattta tttacatgat
     9541 tgtgatggca agattgctat ctccttctga ttttggtata gttggcatgt tgacaatttt
     9601 tatttctgta ggccaagtta tacttgatag tggttttgga caggctttaa taagattaca
     9661 aaaatatgat gatttacatt tttcttcaat ttttataatt aatgttatta tgggagttct
     9721 actctatgga atattatttt atatggctcc atatatttct ttattctata gagaacctag
     9781 cttaacatta atttcaagaa tatctttttt gatttttccc atcaattcac taagtatagt
     9841 ccaatatact ttattagtga aaaaaatgga ttttaaatct atttctaaaa tatctttatt
     9901 ctcgataatt ttatctacaa tttcaggtat tacatatggg tatttttacc ctaatatatt
     9961 tgcactatta attcaaaatg tctcatttta tttttatagg ctacttttat tatggtatta
    10021 tggaaactgg aaattatcat gtcgaatttc atggagtaaa ttacaagatt tgatgccatt
    10081 ctcttttacg ttattagcta caggctttat ttctactgtc gtaggagagt tgtattcatt
    10141 gtctattggt aagttctttt cttcatctgt tttaggttta tattctcaag cagaaaggtt
    10201 ttcgaaaatt ccatcttttt ctataacaga tgttgttcaa cgtgtgactt atcctgcatt
    10261 atcagtgtta caagacgatg atcaaaaatt aaagcattca tatagaatgg ttattatgtg
    10321 cacattcttt atagtattgc ctgtaatgct ttttcttttt attagcgctg gcgaaatttt
    10381 tgaattatta tttactgaaa aatgggaaca gg
//
