LOCUS       c00219_gnlPro..        14292 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BGJMNBAA_291.
ACCESSION   c00219_gnlPro..
VERSION     c00219_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 17:21:08
            Original ID  :: gnl|Prokka|BGJMNBAA_291
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14292
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14292
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6624:11263]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6625..11263
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..14292
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14292
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             3..344
                     /locus_tag="ctg219_1"
                     /transl_table=11
                     /translation="TMKKYLFALTLLLPLLLGGCSSDDQSDDNNSPLIGSWISIDDDVE
                     IFYLDLKKDGTGKWTGTYAGEVENVLRLTWSATETTYHVKYENGNSETKQYRIEGNRLY
                     LGDVIYTRK"
     CDS             complement(358..1632)
                     /locus_tag="ctg219_2"
                     /transl_table=11
                     /translation="MATVKIIILKHQRREDNTWNVKIRITHERQSSYIATTHYVGGELI
                     NKKTFELKERNNPIYDQVMLDVLKIRAELSKLGHSIDLYSAKGLCELMKDKLSNKPEGI
                     NFFDFGYAYADKVLKEGRRIGENYRIAISKFEAFVGNRNLCFSDITSSLLIKFEEDLKS
                     QRSKCGIGNISDSGVRLYISKIQALFNRAKLEYNDEDAGIIRISNNPFAKYKIPKQPIT
                     RKRSLTDEQIRAIKEYRIPENMLGVIIARDVFLMSFFMVGMNTVDMFYLNPPVDDRFEY
                     ERRKTRTRRDDRAFISIKVEPELEPYLERYKDSVGDRAFNFFIRYASHKQFVHKVNLNL
                     KKIGIALGIPDLTLYAARHSWATIARNDCGISMDDVAMSLNHKSGYNVTDTYVKKDWSR
                     IDKANRKVIDFVFHPKKKDEEKAGE"
     CDS             complement(1768..2397)
                     /locus_tag="ctg219_3"
                     /transl_table=11
                     /translation="MLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGVD
                     YVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALG
                     KPVGRQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDH
                     YQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPVQKLYRELLKL"
     CDS             complement(2381..2902)
                     /locus_tag="ctg219_4"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALAFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKHGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(2923..3714)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg219_5"
                     /sec_met_domain="F420_oxidored (E-value: 2.6e-14, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVSHYGVFYPMQTFSKQREVDFKEIPFFIEASSAEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(3711..4043)
                     /locus_tag="ctg219_6"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(4046..4543)
                     /locus_tag="ctg219_7"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(4749..5291)
                     /locus_tag="ctg219_8"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             5409..6392
                     /locus_tag="ctg219_9"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRIFPPAFIKRCEIYGTGEYLIAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALQDAHQNGFRHMEF
                     MDAGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             6625..7029
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg219_10"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3.4e-24, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             7155..8708
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg219_11"
                     /sec_met_domain="CT_Btheta (E-value: 3.2e-291, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             8729..9643
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg219_12"
                     /sec_met_domain="OAD_gamma (E-value: 2e-16, bitscore: 50.6,
                     seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             9669..10100
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg219_13"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.3e-22, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             10103..11263
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg219_14"
                     /sec_met_domain="OAD_beta (E-value: 6.3e-154, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             11411..12742
                     /locus_tag="ctg219_15"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             12757..14049
                     /locus_tag="ctg219_16"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVVLQAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIEDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
ORIGIN
        1 atacaatgaa aaagtattta ttcgcattaa cattattact gcccctcctc cttggtgggt
       61 gttccagtga cgatcaatca gatgacaaca actctccgtt aatcggatct tggatatcca
      121 tagatgatga tgtcgagatt ttctatcttg acctcaaaaa agacgggaca gggaaatgga
      181 ccggaaccta cgccggagaa gtggaaaatg tactaaggct cacttggagt gcaaccgaaa
      241 ccacttacca tgtcaaatat gaaaacggca attctgaaac aaaacagtat agaatagaag
      301 gaaaccgcct ctatttagga gatgtgatat ataccaggaa gtaaagccag ccggggatca
      361 ctccccggct ttttcttcgt ccttcttttt tggatggaac acaaaatcaa ttaccttccg
      421 atttgcctta tcaatcctgc tccagtcctt tttaacataa gtatctgtga cattataccc
      481 agacttatga ttcaatgaca ttgctacatc atccatcgaa ataccgcagt cgttccttgc
      541 tattgtagcc caagagtggc gcgcagcata aagagttaaa tcgggaatac ctaaagcaat
      601 ccctatcttt ttcagattaa gattcacctt atgcacaaat tgcttatggc tcgcatatct
      661 tataaagaaa ttaaacgctc tatcccctac tgaatcctta tatctttcca aataaggctc
      721 aagctccggt tctactttaa tggaaataaa agccctatca tcccgcctgg ttcttgtctt
      781 cctccgctcg tactcaaatc tatcatcaac aggaggattc aaataaaaca tatcaacggt
      841 attcattcca accataaaga acgacatcag aaacacatct ctggcaataa tgacacccaa
      901 catattttcc ggtattcgat actcttttat agctcttatc tgttcatccg ttaaagaacg
      961 ctttcttgta atcggttgct ttggaatttt gtatttagca aagggattat tggaaatgcg
     1021 gattattccg gcatcttcat cgttatattc aagctttgcc cgattaaata acgcttgtat
     1081 cttcgatatg taaagccgaa ccccagaatc agaaatattt ccaataccac attttgaccg
     1141 ttgactcttt aaatcttctt caaatttaat taagagagaa gatgtgatat ccgagaaaca
     1201 taaatttcga tttcccacga atgcctcaaa cttgctaata gcaattcgat aattttcccc
     1261 tatccgccta ccttctttca aaaccttatc cgcataagca taaccaaagt cgaagaagtt
     1321 aattccttca ggcttattag aaagtttatc tttcatcagt tcacataatc ctttagcaga
     1381 atacaaatca atagagtgac ccaattttga aagttcggct ctaattttaa gaacatcgag
     1441 cattacttgg tcataaatcg gattattcct ttcttttagc tcaaaagtct tcttgtttat
     1501 caactcacct cccacatagt gagtagtcgc aatatatgaa gattgacgtt cgtgcgtaat
     1561 ccgtatcttc acattccagg tattatcttc tcgcctttga tgcttgagga tgattatttt
     1621 aactgtagcc atcgttgtaa aacatttaat cgtgcattcc tgtttttcgt aaaacgttcg
     1681 taaaacaatt gcgcaaagat agcaaattaa tttagatatg ctatctttgc gcaatacaaa
     1741 gagaaacagt taattacatc taaaaagcta tagcttaagt agttctctat acagtttttg
     1801 caccggaagt cccattacat tgaagtagct gccggatatg gattctactc cgacaaaacc
     1861 gatccactcc tgcacaccat acgaaccggc tttgtccatg ggctgatagt gatcgacata
     1921 ataagcgatt tcatcttcat caagaatcgc aaaacggaca tccgtcacgg cagcgaaaca
     1981 tttttgccat tctcgggtag tgagacacac accggtaatc acttggtgcg atttaccgga
     2041 gaggctccgc aacatctcta tggcatcctg ccttccgaca ggtttgccga gcgctttgcc
     2101 ttcatgccag acaatggtat cggctgtgat caaaagctct tccggtccga tcatcgactg
     2161 ataggcggct gccttctcac gggctatgaa aagaggaatc tcttcacctt gcaacgtatc
     2221 gggataagat tcgtccacat ccggcaaagt ttttactaca taatcgacac ccaagcccgt
     2281 catcagctct ttccgacgcg gagaattaga ggccaatacg attttataac gatctaagtt
     2341 agcaagcata ctgataaata aataaggtat atactggaaa tcaccatccg aaagcatcat
     2401 cggacaacca ttggccttgt gctttaagca cctgctccac cacatcgcgt ccacagccgt
     2461 atcctccatc ggcatacgaa atgtaacggg caatcgcttt cacctcggga accgcatctt
     2521 tgggacagca gggcaatccg cactcacgca tcacttccat atcgggaacg tcatcgccca
     2581 tgtagagtat ctcctcgtcc gtaagtccgt gtttgtcacg gaaaccacga taatcgtgta
     2641 tcttcaccgc agagccgaag tacagatcgg atacccccaa cccgataaaa cgtttccgca
     2701 cgacatcgct ccgcccacct gtaataatag cgatacgaag cccttttttt acggccaatt
     2761 ggatggcata accgtctttt acatttaccg tacgcatcgg ttcacccgac ggatgcaaag
     2821 ggatgacatt ggcgctcagc actccgtcta catcgaaagc aagtgccttt atccgggtaa
     2881 ggtcgtaatt gattgtgctc atttttattt aatgtttcgg gattattgtc tttcgtgaat
     2941 gcttcggcta agcaactcgt ataaccgctg catggcagga tcatcggcaa gcatccgcaa
     3001 gtgattgccg atcacattct cgtcataacg gatggccggc ccggtctggg ccgtcttagg
     3061 ttccagttcg tgcaccttac gggcggtttc atcaatcaac ggcaacatca cgtcaaacgg
     3121 cagattgtat ttcttaagca actcggcagc aagggcatac atgtgattgg tgaagttaca
     3181 tgtaaacacg gcagccagat ggagactttt acgctgctcc gagtcggcat cgtacacacg
     3241 gttggacagt gtagaggcaa tggctttcag aaacgcggca tcttctgccg aagaagcctc
     3301 tatgaagaaa ggaatctcct taaaatctac ctcccgctgc ttgctgaaag tctgcatggg
     3361 atagaacaca ccgtaatgcg agacatgtcc ttcccagaca ttcatcggga tgctacctgc
     3421 cgtatgcacc atcaatgcct cttcccgctt accttcgaca atgccctgaa gaagttcggc
     3481 aaaggcggaa tctttcagtg aaacaatata cagcttcgca tacgggttca cctctgcgag
     3541 gtctgtcgta tattcggctt ccactttctg tgccagctcg cgggccgact cttccgtacg
     3601 gctatacacc tgtacgatac gaaaaccttt ccgatataag gcttttgcca gattagtggc
     3661 aagatttccg gcaccgataa atacgatcgg cgtatcttct atacttcttt tcatcgtgtt
     3721 gaaatcaaat acaatatacc tccgattatc aataaagcca aaggcagcag ataaccggac
     3781 atcgaaccaa gcaacgaaac aatcaggccg atgttcagca ccaaccacaa tccgagcaat
     3841 accaagccga cggatttatc ccgcttaata aacaggaaaa tcaccgcagt gtaaagcaaa
     3901 agattatcct tattcatcac ccagggtatc cccaaagtgg aaaagtgtat cagtttgtcg
     3961 atcagataga gcacccccat cacaataagg gtgactgctg tggctttgta ggtatcttta
     4021 ttgtttgctt ttaccgcact caccgttact tacctccgaa cttattaata tggatttttt
     4081 cccattgcaa atggtcttca ttaaagggtt tacgttccat ccctttatgc ccgatcgcta
     4141 tgacggacaa cacctgcaac tgcaaaggaa tgtcgagcac accgcgcaca aattcatcgg
     4201 aaggcatccc ggtggcagta tatcgctcac gcacctgcac ccagcaactt cccaatccca
     4261 agtcttcggc ctgaagctga atcataatag aggcaatgga agcgtcctca atccatacat
     4321 cgctcgccaa gggatcggca gtaacgacaa tggccaatgc cgcgtcggca ataaaggccg
     4381 aagcctgctc tttgcaatgt gaaagttcac tgagcaactt tttatcatcg actgcaataa
     4441 attgccagct gttactgcgc tttgaagtag gagccatcag ggccgctttc agcaaagcga
     4501 ctacatcttc ctgagaaagt tcttctccgg taaatttccg catgctgcgg cgatttttta
     4561 ttagttcact gaaattttcc atgtatctat actttgcatt atttgaatat accgccagtc
     4621 accatagaat gcacaaacac acgcgaaccg aggtaccgcc cggcatgccc gtctatataa
     4681 ggtatgccct gcaggacttt gcatgaatcg gcgcgctccg tggcgattcg agcgcaaaga
     4741 taggcaattt attccactct cgtcaactcg ccggtcagtg aatcgatgat aaaaccatgc
     4801 acccggacat ctttcggaat aagcggatgg ttctctatgg aacgaaccgt gcccctgacg
     4861 gacttcaccg gatcgtcgaa tccgcccagc cacgaattaa aatcgacccc gcagtagcgt
     4921 atcatgtcga ttgtttcgga cttgattccc cgctttttca tgtgagctat catttcgtcg
     4981 ctgttcatgt ggcaagcacc gcaatcagaa tgggcaatga ccatcacttc ttctactccc
     5041 aactcgatga tagccaccag cagactacgg atgacactgc cgaaaggatg ggaaatgacg
     5101 gcaccggcat tctttataat ctttacgtct ccgttgtgaa tccccaaagc ggcgggcaac
     5161 agttctgtca ggcgggtatc catacaggaa aggatggcga ttttcttatc aggatacttg
     5221 ttagtgatat acttttcgta tcccctgttc tcaacgaact ttttgttgaa ttcaagaatt
     5281 tcttctaaca taatcaaaaa cggattttat tgtagtatct ccacaaagat agtcacaaaa
     5341 cgacagctca acaaaataag ccctgcaaat gttgtaaaga gaaataaaaa atgtaaattt
     5401 gtcccgatat gccattaaaa ctgactacat attaccaagg aagtgagatt ccggattttc
     5461 ccggaaccaa tacgtttcat tcgaaagagc tatttcagat ctacgaagaa actccgggct
     5521 acaccccact cctgattatg gcttcggaag acggaaaacc cgttgcgcga ctgcttgctg
     5581 ccatccgcaa aagcatccgc atatttcctc ccgctttcat caaacgctgc gaaatctatg
     5641 gcacgggcga atatctgata gcggaagccg acaaggaaag gatattcggc gaaatgctgg
     5701 agcacctcac cacggaggct ttgcggaact cgtttctaat agaattccgc aatctggaga
     5761 acgccatgtt cggctacaaa tatttccggt ccaacagata cttccctgtc aactggctgc
     5821 gggtacgaaa ctcgcttcac ggcatcgaaa acgccgaaca gcgtttcagc ccctcccgta
     5881 tccgccagat caaaaaaggc ctgaaaaacg gagcaaaagt agacgaggca cgtacggtag
     5941 aagagatacg cgaattttcg aatatgctga ggcatctcta ttcgtcccgc atccgtaaac
     6001 attttcccaa catcatcttt ttccaacaca tggacacccg gctgattcac agccggcagg
     6061 caaagatttt catcgtccgc tacaaagaca aaattatcgg aggctctgcc tgtatctatt
     6121 cgggaaacga tgcctatctc tggttttcgg gaggtatgcg aaagacctat gccttgcaat
     6181 acccgggtat actggctgta tggaaagccc tccaggatgc ccatcaaaac ggattccgcc
     6241 acatggagtt catggacgcc ggactcccat ttaagaagca cggctatcgt gacttcgtgc
     6301 tccgcttcgg tggcaagcaa agcagcaccc ggcgatggtt ccgtttccgc tggcaatggc
     6361 tgaacgacct gctgatcaaa atatacgtct gaacatccgc ctgtctcagg gatcagcgcc
     6421 aaccctctcc gtcttttaaa ccacccccct taggttttaa accaacgata cctgcctttt
     6481 aaacccatgc accttaggtt ttaaacctat tttcaccata attaattgca gaaaaatttc
     6541 tttattaaac aagaattgat tttctttgtg ctgttttata ccattccgaa aagacgatta
     6601 ataccaaaat ttaaaaatat agttatgaag atttcacaca ttgaacattt gggcattgcc
     6661 gtaaaaagta tcgaagaagc ccttccgtat tatgaaaacg ttttaggttt gaaatgctac
     6721 aacatcgaaa ctgtagaaga tcaaaaagta agaacagcct tcctgaaagt aggtgatacc
     6781 aaaatcgaat tactggaacc cacatgtccg gaaagtacca tcgcgaaatt cattgaaaac
     6841 aaaggtgcag gtgttcatca cgtagcattc gccattgaag acggcgtagc caatgccctg
     6901 gccgaagccg aaagcaaaga gatccgcctg atcgacaaag ctccgcgcaa aggtgccgaa
     6961 ggcctgaaca ttgctttcct tcacccgaaa tcaactctgg gcgtactgac agaactctgc
     7021 gaacactaaa aagatgtacg attcggacga tccgcgccac ggacaaacgg aatttttctt
     7081 tgcattaaat tccccatccg ggttgtcaat cgtccggttg taaatattat aaccctttaa
     7141 attaagaaaa actcatgagt aaccagcttg aaaaagtaaa agagcttatt gaacttcgtg
     7201 ctcaggctcg tttaggtggt ggcgaaaagg ctattgaaaa acaacacgcc aaaggcaaat
     7261 atacagcccg cgagcgtatt gcacagttgc ttgacgaagg tagtttcgaa gaactggata
     7321 tgtttgttca acacagatgt accaatttcg gacaagagaa aaaacatttc ctcggcgacg
     7381 gtgtggtaac cggttatgga acgatagaag gtagattagt atatgttttc gcacaagatt
     7441 tcacagtatt cggtggttca ctgtcggaaa ccatggcaca aaagatctgt aaagtaatgg
     7501 atatggccat gaagatgggt gcccctgtta tcggtatcaa cgactcgggt ggcgcacgta
     7561 ttcaggaagg catcaacgcc ctgtccggtt atgctgaaat cttccagcgc aacatcatgg
     7621 cttcgggtgt catcccacag atttcaggta ttttcggtcc gtgtgccggc ggtgcggttt
     7681 actctcccgc cctgacggac ttcacgctga tgacggaagg tacatcttac atgttcctca
     7741 ccggaccggc tgttgtgaaa acagtaacgg gtgaagacgt gtctcaggaa gatctgggtg
     7801 gtgcaagcgt acatgccagc aagtccggtg taactcactt cactgccgaa accggtgaag
     7861 aaggtctggc gattattcgc aagcttctca gctttattcc gcaaaacaac ctggaagaag
     7921 ctccattggt gaactgtacc gaccccatcg accgtatgga cgacctgctg aacgagatca
     7981 tccccgacag cccgaacaaa ccgtacgata tgtacgaagt gatcggcgcc atcatcgata
     8041 acggagaatt cctggaagta cagaaagact atgcgaaaaa tcttattatc ggttttgccc
     8101 gtatgaacgg acaatcggta ggtgtggttg ccaatcagcc taaatacctc gccggagtac
     8161 tcgacagcaa tgcttcacgc aaaggtgcac gcttcgttcg cttctgcgac gcattcaaca
     8221 ttccgctggt gacattggta gacgttccgg gattccttcc gggtacgggt caggaatata
     8281 atggtgtaat ccttcacgga gccaagttgc tgtacgctta tggtgaagcc actgtgccca
     8341 aggtaactgt taccctgcgt aaatcttacg gtggttcgca catcgtaatg agttgcaagc
     8401 aactccgcgg cgacatgaac tatgcatggc cgacagccga aatcgccgta atgggcggtg
     8461 ccggtgcagt agcggtattg tatgccaaag aagccaaaga tcaggaaaac cctgctcaat
     8521 tcctggcaga caaggaagcc gagtacacta aactgttcgc caacccgtac aatgcagcca
     8581 aatacggtta catcgacgat gttatcgaac cgagaaacac tcgtttccgc gtgatccgcg
     8641 ccctgcaaca gctgcagacc aaaaaattaa ccaaccctgc taaaaagcac ggtaatattc
     8701 cattgtaaca aattaaacat cgattgttat gaataagaaa agaatcggga tatttatcgc
     8761 tctgctggca atggtttgca tggggctcag ggcgcaaagt gccaccagtc tgagaatcaa
     8821 tgaggttttg gtcgtcaacg accagaacta tcaggatgac tacggactgc acaatgcgtg
     8881 gatagagata ttcaacacct ctttcgcttc tgtaaatctg gaaggttgct ttctgacgaa
     8941 cgataaaaac aatccgacca aatatcctat tcccaaaggc gacgtgctga ctctgatcaa
     9001 gccgcgccaa catgctttgt tctgggcaga cggaatgcct aaccggggta cattccacgt
     9061 gaactttacg ctcgacccga acaaagagaa ttacattgct ttgtatgact ctaacggtaa
     9121 aactctgatt gacgaagtaa ccatacccgc cggtcagctt gccgaccgtt catacgctcg
     9181 cgaaaaagac ggaagtgcca actgggtagt aaaaggtgaa ggagaacaca gctatgtcac
     9241 tccgagcacc aacaatatga ctatcgacaa aaacccgaag atcgagaact tcaagaaaca
     9301 cgactctatc ggtatcggta tggccatcat cgccatgtcg gtcgtattca taggtttggt
     9361 actcttgtat ctttcattca aggcggtagg taacgtagct gtcagattgg gtaagaaaaa
     9421 cgcgatgaaa gccaccggta tcaccgacaa gacggaagcg aaggaaaaga acctgggtag
     9481 ccacacaggt gaagaaaccg ccgcaatcgc catggctttg catgaatacc tgaatgacgc
     9541 tcacgacgtt gaagacatga ttttgaccat caacaaagtg aaacgcacct actcaccctg
     9601 gagttcgaag atctacacac tgcgtcagac tccgaaaaga taattactaa ccctaataaa
     9661 atgaagcaat gaaacaatat aaatataaaa tcaacggcaa cctttacaac gttacagtga
     9721 acgatgtaga agataacata gccaacgttg aagtgaacgg aacctcttat aaagtagagt
     9781 tggacaagcc cgtcaaagcc gctccgaaac cggtgacccg tccggcagcc gctccgaaaa
     9841 cggaaacagg tgctccggta gtaaccaaac aaccgacagc ttccaaaaaa gacggtgtga
     9901 aatctccgct tccgggcgtt atcctcgaca taaaagtgaa agaaggggat accgtgaaga
     9961 gaggccagac gatcatcatc cttgaggcta tgaagatgga aaacaacatc aatgccaata
    10021 aagacggaaa agtagcagaa attaaagtta ataaaggaga ttctgtactt gaaggtacag
    10081 acctcgtaat cattgaataa ttatgggaga tttcgtatca ttcttaggga ataaccttgt
    10141 tgacttctgg ggatacaccg gttttgcgaa cgcgacaccc ggacatcttt tcatgttgct
    10201 aatcggtctc ttctttatct accttgccgt agccaaagaa tttgaaccga tgctgctgat
    10261 ccccattggc ttcggtattc tgatcggtaa tattccattc aatatggaag ccggattaaa
    10321 agtgggtatt tacgaagaag gttcggtact gaacatcctt tatcaaggag taacctccgg
    10381 ctggtatccg ccgctcattt tcctgggtat cggagccatg acggacttct cggcgctgat
    10441 ctccaacccc aaattgatgc tgatcggagc tgccgcgcaa ttcggtatct tcggcgcgta
    10501 tatcattgcc ctgctcattg gattcgaacc caaccaggcg ggtgctatcg gtatcattgg
    10561 cggtgccgac ggaccgacgg ccatcttcct ttcgtccaaa ctggctccca acctgatggg
    10621 tgccatcgct gtgtcagcct attcttacat ggcgctggtg ccggtgatac agccacctat
    10681 catgcgtgcg ctaaccacca aacacgagcg tctgatccgc atgaaaccac cgagaatagt
    10741 atcgcatacg gaaaaagtaa tcttccccat cgtgggtctg ttgcttacat gcttcctggt
    10801 tccttcgggt ctgcctttgc tgggtatgct gttcttcggt aatcttctga aagaaagtgg
    10861 agtaacccgt cgtttggcaa atacggccag tggtccgttg atcgatgtga tcactatcct
    10921 gttgggactg actgtgggag cttctaccca agcttcacaa ttcctcacct gggattctat
    10981 cttgatcttt atcctcggtg cattctcttt catcatcgca acagcgtcag gtgtcatgtt
    11041 tgtcaaattc ttcaatctat tcttgaagaa aggcaataag atcaatccgc tgattggtaa
    11101 tgcaggtgta tccgccgtac ccgactcggc acgtatttca caggtaatcg gtttggaata
    11161 tgatccgacc aactatctgc tgatgcacgc catgggtcct aacgtagcgg gggttatcgg
    11221 ttcggctgta gctgccggta tcctgctcgg attcctcatg taaacgatat tttttcatta
    11281 gtaaggtaga cgtccttctt ttcgcaaaga agggcgtctt ttttttgcgt taatctatct
    11341 aaaagatatt acgaaccttt cgtagaatgg atatttttac taacttgcgg acaataaaac
    11401 aatacgtcct atgagaacaa gaacaatgaa accactcttc cttattttct gtctttgcct
    11461 cagtccccta ctgatgggcc agaatcaaaa caaaattcag gaagcaatgg caaactatga
    11521 ctacgagact gccgttgaac tgataaacaa ggaacctccc accatcccac tgttaatgca
    11581 gaaagcaaaa gccctgaaag gaatcggcag caatgcggaa gctctacgtt ccatccgcca
    11641 agtgatagcg gaagactcca ccaaccaaca ggcacacatc gaagcagcgg aatgctgtaa
    11701 agcaatggcc aagtacaacg atgcgctgga ctactaccgg aaagccatca gcctgaatcc
    11761 caaaaacaag tatgcccgtt tgcaattcat caacctgctt tgcaacacca aaaactatgc
    11821 tgaggctttt ggagaaagtt caatgatgtc cgaaacggac agttcggccg tagtgctcca
    11881 cctacaggct caaagccttg aagggatgca acagatacta ccggctatcg gttgctatga
    11941 agtcattcag gataaatatc cggacgatta tctggctgcg gccaaactcg gaaacctgaa
    12001 cattgtggct ggatatcccg aatatgccat ccaagctacc gaacgctata gggaacggga
    12061 ctccaccaac ctgattgtca accagcaaaa cgctctcgcc tactgccacg ccgaacaata
    12121 tccgacagcc atcaagcgct atgaaaagct gtgccaacag ggggacagca gtacacagac
    12181 cttatactac ctgggagtca gctattacgc agatgaatat tattacgaag cgcacgcgtg
    12241 tttcagcaaa ctgcaaaaag agatggaaga aaatcccaat ctgctctatt atctgggacg
    12301 ttgctgcgcc aagacttcct ggaaaaaaga aggcatcgaa cacctggaga aagctatcga
    12361 actgaccatt cccaaagaca gcaccatgat ccgactttac aaaggcttgg tggattgttg
    12421 taaactggct caggatactc caaagcaaat ccaggctctc agagaactgt acaaatatga
    12481 caagacgaac cataaacttc tttatgacat cgcctggaac tattcatatc aactcaaaga
    12541 caacaaatcg gccgaacgtt atctgcaggc tttcttaaaa acccgaaagg cgaatgccag
    12601 gaaagaagaa ccggtgagtg agaaagggga acttgtactc ggacttgaaa attattacaa
    12661 cgctgccgaa aattggctga aagacttaca gaaagaaaag ttcttcaaag aaggaatacc
    12721 gttagaaagt cagaaacaat agaatctgtc ccccccatga aacattggat actcctcctc
    12781 tatctggggt tcagcgtagt gctgcaagcc cagaacaccg cctccgttca agaagcaatg
    12841 gcaaactatg actataaaac ggtgatcaga ctgattgatg aagaaagtgc atcaccacag
    12901 ttactcatac agaaagccaa agctttaaaa ggtttagggc gtaccgccga agccctgtcc
    12961 actttgcaac atatcattat cgagctgccc gaaaatcagc aggcattggt agaggcagca
    13021 gaatgttgca ggcaattgag caaatttaac gaggccttgg ggtattatcg gaaggtgatg
    13081 gaactcaatc ccgaacatat ttacgcacac ttgcaataca cccgcttgtt atacaactat
    13141 cagcgatacg gcgatgcatt gcgtgagagt atcgcattgg ccaggaaaga cagttccgcc
    13201 accgtattgc gactgatggc ggaaagcatg gaaggagccg gcatgccggt agaaagtatg
    13261 ttttgctatc tttccatcat caggaaatat ccctccgact atctctcggt agctaagctg
    13321 ggcagtatct tcaatacaat gaaagattac gaaggggcaa ttgccctgac agaggcatac
    13381 cgccggacgg acagcaccaa tgtagaagtg aaccgtcaaa acgcactggc gtattgtctg
    13441 cgcaaagaat atcccaccgc catcaaacgt tatcaggatc tgaccgcccg gggagacagc
    13501 acactgctga catgttatta tctgggagtc agctactacg ctacgaaaga atactataaa
    13561 gcacgcgatt ggctgctcaa agcaaaatca tgccagtcac ccggcgccaa cctactctac
    13621 tatttgggac gttcgtgctc caagacatta tggaaacaag agggaatagg atatctgaac
    13681 caggctatcg ccctgactat ccccgccgac agtatcatgg agcgcttata ctcaggcttg
    13741 gcagactgct acaggcaaac caagcaaacc cgggaccaaa tcaaggctac caaagaacaa
    13801 tacaaatatg cccctgacaa gcatatttta ctttataact tggcgttctt atcggacaaa
    13861 attgaagata ctaaagccac agagcattac ttgcaggctt ttctgcgaac aaaatccaaa
    13921 caaaatgcag tactacagca gccggatgat gacgaagaag aacccgcacc ctacatagat
    13981 tactacaaaa gtgccaccaa taaattggaa agcatccgaa aagagaaatt cttaaaggga
    14041 gaaaagtgaa ttgatcggat agatgcatcg tttcggacaa ttcaccactg agtgcagaca
    14101 gagtttcaca gagggagaat aatggaaaat aaatttgaag atgtgcggta gaaggcacag
    14161 tggcacgtaa ccgaagtcac atcggcacgc agccgaaatt acggtgctgt atagctaaag
    14221 ttacggtgct gtgtagataa agttacggtg ctgcgtagcc aaagttacgg tgctgcgtag
    14281 ataaagttac gg
//
