LOCUS       c00321_gnlPro..        14981 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JAOHLMFG_432.
ACCESSION   c00321_gnlPro..
VERSION     c00321_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 17:26:16
            Original ID  :: gnl|Prokka|JAOHLMFG_432
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 10881
            Orig. end    :: 25862
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14981
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[20881:24301]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13420
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14981
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14981
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1472..2389
                     /locus_tag="ctg321_11"
                     /transl_table=11
                     /translation="LIGANCLTDGAASVAKRFRIPSIVIGLTIVAFGTSAPELTVSVSS
                     ALKGSADIAVGNVVGSNIFNTLMIVGCTALFAPIVITRNTLRKEIPLCILSSIVLLICA
                     NDVFLNKASSNILSISDGLILLCFFTIFLGYTFAIASPTNNTQPEEEIKSLPMWKSVLF
                     ILGGLAGLIFGGQWFVEGASNIARHLGVSESVIGLTLVAGGTSLPELATSIVAALKKNP
                     EIAIGNVIGSNLFNIFFVLGCSASITPLRLTGINNFDLFTLVGSGILLWFFGLFFAKRT
                     ITRIEGSILVLCYIAYTTYLIYQI"
     CDS             2592..3614
                     /locus_tag="ctg321_12"
                     /transl_table=11
                     /translation="MLNTFNKKKNAAFEFCEAEYFLAYKDGKIVGRIAGIINHRANATW
                     NKKDVRFGWIDFIDDLEVSSRLLQTVEEWGKSKGMENIQGPLGFTDFDAEGMLIEGFDQ
                     LSTMATIYNHPYYPQHMEKLGFEKDADWVEYKIYIPDAIPEKHQRISDLIQRKYNLKIK
                     KYTSSRKIAADYGQAIFELMNEAYSPLYGYSPLSQRQIDQYVKMYLPIVDLRMVTLITD
                     AEDKLIAVGISMPSLSEALQKSHGRLLPLGWYYLLKALFMKRRAKMLDLLLVAVKPEYQ
                     NKGVNALLFSDLIPVYQKLGFIFAESNPELEMNGKVQAQWEYFKTEQHKRRRAFTKKID
                     "
     CDS             3620..5491
                     /locus_tag="ctg321_13"
                     /transl_table=11
                     /translation="MEENELIPVDNNPVEYTDDNIRHLSDMEHVRTRPGMYIGKLGDGS
                     HPEDGIYVLLKEVIDNSIDEFKMQSGKKIEIRVEENLRVSVRDYGRGIPQGKLIEAVSV
                     LNTGGKYDSKAFKKSVGLNGVGVKAVNALSSNFEVRSYRDGKVRCATFTKGELVTDHTE
                     DTEEENGTYIFFEPDETLFLNYSFRPEFIETMLRNYTYLNTGLAIIYNGQRILSRNGLV
                     DLLNDNMTATGLYPIVHLKGEDIEIAFTHTGQYGEEYYSFVNGQHTTQGGTHQSAFKEH
                     IARTIKEFYNKNQDYTDIRNGLVAAIAVNVEEPMFESQTKIKLGSTNMSPGGITVNKFV
                     GDFIKQEVDNFLHKHADVAEIMLQKIQDSEKERKAIAGVTKLARERAKKANLHNRKLRD
                     CRVHLNDVKGKGLEEESCIFITEGDSASGSITKSRDVNTQAVFSLRGKPLNSFGLTKKV
                     VYENEEFNLLQAALNIEDGIEGLRYNKVIVATDADVDGMHIRLLLITFFLQFFPDLIKK
                     GHVYILQTPLFRVRNKKKTLYCYTEEERVNAIKELSPNPEITRFKGLGEISPDEFRHFI
                     GKDMRLEQVSLRKTDTVKELLEFYMGKNTMERQNFIIDNLVIEEDIA"
     CDS             5494..5946
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg321_14"
                     /sec_met_domain="CTP_transf_like (E-value: 1.8e-21,
                     bitscore: 67.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHYSVVQRTLTFMDEVVIGIGINENKNTYF
                     PIEKRVEMIRKFYKDEPRIKVESYDCLTIDFARQVDAQFIVRGIRTVKDFEYEETIADI
                     NRKLAGIETILLFTEPELTCVSSTIVRELLGYNKDISMFIPKGMEM"
     CDS             complement(5898..6071)
                     /locus_tag="ctg321_15"
                     /transl_table=11
                     /translation="MANSASCNFRMAGEPKFCACSPKTEHKPISRYIILFMITWVYYIS
                     IPLGMNILISLL"
     CDS             complement(6079..6270)
                     /locus_tag="ctg321_16"
                     /transl_table=11
                     /translation="LYDEQRIFDHLKLYTYPFEIALERFIHFLHLFGIRIGGMRVELCQ
                     HFYDGRFNEFVFIDRIYI"
     CDS             6508..7584
                     /locus_tag="ctg321_17"
                     /transl_table=11
                     /translation="MIQPKIGYIRINRFGATTAEEFLKALKELQKKGMKDLILDLQGNG
                     GGYLNAAIDLANEFLGQKELIVYTEGRSAQRSEFFAKGNGNFRNGRLVVLVDEYSASAS
                     EIVTGAIQDWDRGVVVGRRSFGKGLVQRPIDLPDGSMIRLTIARYYTPAGRCIQKPYDS
                     SINEKPGKGKSSESSIEKYNQDLIDRYNHGEMVSADSIHFPDSLKCQTKKLGRTVYGGG
                     GIMPDYFVPVDTTLYTDYHRNLVAKGVVIKTTMNFIEKNRKALLDKYKTFEKFNEKFEI
                     DDQLLNYLREAADKEKIEFNEEQYNKALPLIKAQLKALIARDLWDMNEYFQVMNATNKS
                     VERALEILNDKEYEKILK"
     CDS             7917..8213
                     /locus_tag="ctg321_18"
                     /transl_table=11
                     /translation="MTGRKRRTRFMTTCIYPIRITVVGTLTVKSIFHTIRNHDCLSHTR
                     TDVNGIFQQLFIFIDTCIYSHRHRYTYRNIRCRFRKGFAIIPRKLTIKTVYFM"
     CDS             8773..9282
                     /locus_tag="ctg321_19"
                     /transl_table=11
                     /translation="MTQRITNFMKDICDYLGEQMPCGAFIDLKCQELMYLIICYYPIPQ
                     LSKFFYPISSYTESFQYFVMQNYEKVKNVEEFAHLGGYTTTTFRRLFKNMYGVPVYEWI
                     LSKKREGILEDLQHTKQRITEISNRYGFDSLSHFAHFCKASFGDSPRALRTRAARGEKI
                     TALKTE"
     CDS             10001..10654
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg321_20"
                     /sec_met_domain="SucD_FumR (E-value: 3.7e-121, bitscore:
                     392.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVTGIALVLFLTFHMAMNLVAIISAEGYNLVCEFLGANWYALVA
                     TLGLAALFVIHIIYAFWLTIQNRAARGSERYAVVDKPKTVEWASQNMLVLGIIVILGLG
                     LHLFNFWAKMQLPELVHNMGGVADTTYAADGVYHIMNTFSNPVYVVLYLVWLGALWFHL
                     THGFWSSMQSLGWNNKIWINRWKCISNIYSTIVVVCFALVVVVFFVKSLACGAC"
     CDS             complement(11208..11354)
                     /locus_tag="ctg321_21"
                     /transl_table=11
                     /translation="VSSETFDFTSYEVTGNDTARTSFNYNEVEHFVTSVKFNSTFLYLT
                     AQC"
     CDS             11754..12635
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg321_22"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.5e-15, bitscore:
                     45.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7.9e-39,
                     bitscore: 123.3, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNNTGLAVFLDFKYAIDRLGEDVVRARYGNLFDMYEEITDENPYK
                     TPMMIFPAIHYTMGGIWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQIQVPRFSTDLPEFAAAEKEVKDKIQKIKAVNGKHSVDSIHKKLGHI
                     MWDFVGMARTKESLQKALTGIEEVKKDFWTNVRIPGDVNELNVELEKALRLIDFIEVGM
                     LMARDGLNREESCGGHFRTEYQTPEGEALRDDKNFSYVACWKYTGENSEPELIKEDLNY
                     QFVKVQTRNYKS"
     CDS             13136..13420
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg321_23"
                     /sec_met_domain="Fer4_7 (E-value: 2e-13, bitscore: 41.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.3e-07, bitscore: 22.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-07, bitscore: 22.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAAACIGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKVEAARR
                     AKAMLSKMDELGFGNCTNTRACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(13501..14631)
                     /locus_tag="ctg321_24"
                     /transl_table=11
                     /translation="MNKTFRKACAKLHLWLGLLSGIVVFIVCITGCMYAFKDEITDATQ
                     PWRFVAPLEKEFLPPSRLLAIADSVMGGASATAITYGERSDAAWVDYYQPEAGMSTVFI
                     NPYSGQVLKSVVNHNGDFDFFRLVLSGHRTLWLPREIGSPIVGYSVLIFLITLITGVIL
                     WWPRSWTRKALVQRLTLKRPFTFSRLNFDLHNVAGFYAALVLAVLCFTGLIFSLNWFSR
                     GVYSITSGGEELKPYVLPVSDTLQVVNRVTNPLDRLYTQLRLEEPAAKTFYFALPGQAD
                     GVYRVSVVHKRGSYYRTDNLFFDRYTLVSLKGAGPYAGKYTEASPADKFRRMNLEIHDG
                     RIWGLPGKIIMFLASLTGASLPVTGFIIWYRKHRKR"
     CDS             complement(14638..14979)
                     /locus_tag="ctg321_25"
                     /transl_table=11
                     /translation="LKPAHIKYIGNGLVFAEVSTISPQTSADRWGDKSLKCCIIDLNNK
                     TVRDIKEIPVHNGDGGRRFAALVDGGYVYRPVTTSEGTYIYQVDPQAATAVRGAKVSTT
                     FVGGFFRLD"
ORIGIN
        1 ccagtttaaa aggacgcata taagtaatga ccagccccgc aatcacatta ccgattaccg
       61 tgctggatcc taaagaaatg atcagaccga caaaaacaga tatcccctgg aatactccat
      121 tcttagcccc cggcaaatag ggatagatca tcgcaatcat aaaagcataa agcagaaaac
      181 ggatgatatg ataagtaggc attgcccagt cgggatagaa gccaccgaac ttgagccgcc
      241 ccgcctctac ctcacgggac aagtagtgaa ccaagcgcac cagatactta acggcaaaac
      301 agatgataag aatggcaaac aaattgggaa tataatcgac tatacctacc agtatgttct
      361 tgatcgggtt ccagatatac gaaaatatct gataggccag ccccttggtc tgtgggaaga
      421 tagcgaacaa aagggggatg gtaatcaaca attggagaag catgattaca tagcgcagca
      481 aattggaaag gaagatcaac aggttgacct gccgctgcgt atccaataac tcgtaattct
      541 gaatggagat cggcttcagc ctggtatcct tcagcttttg gatacgtacc ttcagtttac
      601 ggaacagcca gcctgtaagc caaaacaaca gatactgccc tgccaatacc aggacaaaat
      661 acagaatacg cttacccagt tgccacaaac tatgctcctc cttcaactct ttcagtttct
      721 gtactacaat cttccgctta tccgttgcca actgctcgcg cgaacgtcct tcccatagtc
      781 cgtcctggtc ggtaaacgaa gcaatgactt tattgccgta catcagatcg gttacgatat
      841 cgctgctctc gatatagaca gaatcgggat gcagggtaaa ccgtttaccc aactgcatga
      901 tggccgcatc gatcatttcg gcccgctgca aaggggtata tcccccacgc ttggtataca
      961 aataaaacaa tgtatcgcct tcgaccacta ccggtactcc cggcgtaaac tggcgaagtg
     1021 agtcgatacg tgccctttgc tgagctaatt tcacagagtc ggcagcaaaa gctttcagcc
     1081 tcatctgctc catttccata cgcatattgg cttcgctcag acgcgcctcc tccagctctt
     1141 tcttcatatc tgccatccgt acggaatccg aatcgttccg gactgcggtc cgggtagcca
     1201 cactatcacc cgtcaatatc tcacgaaccg cctttcccaa ctgtgcgcac atattgttgg
     1261 tcaccaacag aaacaacaaa aggccgaata atctgttctt tttcatatca aaaactcata
     1321 aagtaattgt caccggaatg gataaacgtg ccaaacatac agattgtttt tgacatagca
     1381 tagatcgaaa tcattatatt tgcacccgaa tccgtaattt aaaggtatag acatggatat
     1441 attactgctt attggaggat tactcctcat tttgataggt gccaactgcc tgacagatgg
     1501 tgctgcgtcc gtagccaagc gattccgtat tccttccatc gtaatcggcc tgactatcgt
     1561 agctttcgga acttccgccc cggaactgac cgttagcgta tcgtccgccc tgaaaggtag
     1621 cgcggacatc gccgtaggta acgtagtggg aagtaatatc ttcaatacat tgatgatcgt
     1681 cgggtgcacc gctctatttg ctcctatcgt aattacccgg aatactttgc ggaaagagat
     1741 tccgctatgc attctctcct ccatcgtcct gctgatatgc gccaatgacg tttttctgaa
     1801 taaagcttcc agcaacatac taagcatctc ggacggactg attctgctct gtttcttcac
     1861 catcttcctg ggctacacat ttgccatagc ctcacccaca aacaatactc aaccggaaga
     1921 ggaaatcaaa agcctcccga tgtggaaatc cgtacttttc attctgggcg gattggccgg
     1981 acttattttc gggggacaat ggtttgtaga gggagcaagc aacatcgcac ggcaccttgg
     2041 cgtcagcgaa tctgttatcg gactcacact ggtagccgga ggtacctccc taccggaact
     2101 tgctacatcg atagtggctg ccttgaaaaa gaatccggaa atagccatcg gtaatgtgat
     2161 cggcagtaat ctgttcaaca tcttctttgt attgggatgc agtgcttcca tcactccctt
     2221 gcggctgaca ggcatcaata acttcgacct tttcaccttg gtcggttcgg gcattctgct
     2281 ctggtttttc ggattatttt ttgccaaacg caccatcaca cggatcgaag gaagtattct
     2341 ggtgttatgc tatatagcct acaccaccta tctgatctat cagatttgat aacatcgaga
     2401 cacatagttt ttagttttcg tacgtggtaa tttaaagatt atcacgtatc tttgccccct
     2461 catcataaat acaagctatg gccattacaa ttaaaaaggt atcgacaaaa agagaactta
     2521 aaaaattcat tcgttttaat tacgaattat acaaagagaa tccttattcc gtacctgacc
     2581 tctacgacga catgctgaat acattcaata agaagaaaaa tgcggcattc gagttctgtg
     2641 aggccgagta ctttctggct tataaagacg gaaaaatcgt agggcgcatc gcaggtatta
     2701 tcaatcaccg tgccaatgcc acctggaaca aaaaagatgt ccgtttcggt tggatcgact
     2761 tcatcgacga ccttgaagta tcttccagac ttctgcaaac cgtagaagaa tggggtaaat
     2821 ccaaagggat ggagaacatt cagggacctc ttggatttac cgacttcgac gcagaaggta
     2881 tgctgatcga aggattcgac caactcagca ccatggcaac catctacaat catccctact
     2941 atccgcaaca catggagaaa ctgggatttg agaaagatgc cgactgggtg gaatacaaaa
     3001 tttatattcc tgacgccatc cctgagaagc accagcgcat atccgatctt attcagcgta
     3061 aatataacct caagataaag aaatatacct catccagaaa gattgcagcc gattacggac
     3121 aagccatctt tgagttgatg aacgaagctt atagtccgct gtacggatac tctccgcttt
     3181 cgcaacggca aattgaccaa tatgttaaaa tgtaccttcc gattgtcgac ttgcgaatgg
     3241 taaccctgat cacagatgcg gaagacaagt taattgccgt aggcatttca atgccttcac
     3301 tttcggaagc gttacagaaa tcgcatggac gccttttgcc cctcggatgg tattatctgc
     3361 taaaggcatt gttcatgaaa cgacgcgcca aaatgcttga cctgctgctt gtagccgtga
     3421 aaccggagta ccaaaacaaa ggtgttaacg ctttgttatt ttccgattta attccggttt
     3481 atcaaaaatt aggttttatc tttgcagaaa gcaaccccga actggaaatg aacggaaagg
     3541 ttcaggcaca atgggaatac tttaaaaccg aacaacataa acgtcgtcgt gcgtttacta
     3601 agaagataga ctaaaaacaa tggaagagaa cgaactgata cctgtagaca acaaccctgt
     3661 agaatataca gacgacaaca tccgccacct gagcgacatg gaacatgtgc gcacccgtcc
     3721 gggtatgtac atcggtaagc tgggcgacgg ttcgcatccc gaagacggaa tatatgtcct
     3781 tctgaaagaa gttattgaca acagtatcga cgagttcaaa atgcaatccg gcaagaagat
     3841 cgaaatcaga gtggaagaga atcttcgtgt cagtgtacgc gactacggcc gcggtatccc
     3901 acagggaaaa ctaatagagg cagtcagtgt gctgaacacc ggtggtaagt atgacagcaa
     3961 ggctttcaag aaaagtgtcg gactgaacgg tgtcggcgtg aaagctgtca atgctttgag
     4021 ctcaaacttt gaagtacgta gttaccggga tggtaaagtg cgttgcgcca cctttaccaa
     4081 aggagagctg gtgacagacc acacagaaga tacggaagaa gaaaacggta cttacatctt
     4141 cttcgaaccg gatgaaactt tattcctgaa ttatagtttc cgtcccgaat ttatcgagac
     4201 gatgctgcgc aattacacat acctgaacac cgggctggca attatctata atggccaacg
     4261 gatcctttcg cgcaatggcc tggtagattt gctgaatgat aacatgacag ctaccggcct
     4321 ctaccccatc gtacatctga agggcgaaga tatcgagata gcctttaccc ataccggaca
     4381 gtacggagag gagtactact catttgtaaa cggtcagcat accactcagg gaggtaccca
     4441 tcaaagtgct ttcaaagaac acatcgcccg caccatcaaa gagttctata acaagaatca
     4501 agactatact gacatccgta acggactggt agccgccatt gctgtcaacg tggaagaacc
     4561 tatgtttgaa agccagacca aaatcaaact cggctctacc aatatgtcgc cgggaggcat
     4621 cacagtaaat aagttcgtgg gtgacttcat aaaacaggag gtagacaatt tcctccacaa
     4681 gcatgccgat gtagccgaaa tcatgttgca aaagatacag gattcggaaa aagaacgcaa
     4741 agccattgcc ggagtgacca aactggcacg tgaacgcgcc aagaaagcca acttgcacaa
     4801 ccggaagctg cgtgattgcc gcgtccacct gaacgatgtg aaaggcaaag ggctggaaga
     4861 ggaatcgtgc atcttcatca ccgagggtga ctcggcaagc ggctctatca ccaaaagccg
     4921 ggatgtaaac acacaagccg tattcagcct ccgcggtaag cctctcaact ctttcggcct
     4981 gaccaaaaaa gtagtttacg agaacgaaga attcaatctg ctgcaagctg cattgaatat
     5041 agaagacggt atcgaaggct tacgctacaa caaagtgatc gtggctaccg atgccgatgt
     5101 ggatggtatg cacatccgct tgttgctgat tactttcttc cttcagttct tccccgatct
     5161 gataaagaaa ggacatgtat atatactcca aactcctctc ttccgcgtac gcaataaaaa
     5221 gaaaacgctt tattgttata ccgaagaaga gcgtgtaaat gctattaaag agcttagccc
     5281 gaatccggaa atcacccgtt ttaaaggttt gggggaaatc tcgcccgacg aattcagaca
     5341 ctttatcggc aaagatatgc gtctcgaaca agtatcgctg cgcaaaacag acacggtaaa
     5401 agaactactc gaattttata tgggtaagaa tacaatggaa cggcaaaact ttattattga
     5461 taatctggtt atagaagaag acatcgcata aacatgagaa gagctatctt tccgggaacg
     5521 ttcgacccgt ttaccatcgg acactactcc gtagttcaac gcaccctgac attcatggac
     5581 gaagtggtca tcggtatcgg tatcaacgaa aacaagaata catattttcc gatcgagaaa
     5641 cgtgtggaaa tgattcgtaa gttctataaa gacgaacccc ggatcaaggt cgaatcttac
     5701 gattgcctga cgatcgactt tgcccgtcag gtagatgccc aattcatcgt tcgcggtatc
     5761 cgtaccgtga aagacttcga atacgaagaa acaattgccg atatcaaccg gaaactggcc
     5821 ggcattgaaa ccattctgtt atttaccgaa ccggaattga cctgtgtcag ctctaccatc
     5881 gtccgcgaac tgcttggcta taataaggat atcagtatgt tcattcccaa agggatggaa
     5941 atgtaataaa cccatgtgat catgaaaaga ataatatacc tgcttatcgg tttgtgttcc
     6001 gttttgggac tacaggcaca gaactttggc tcacccgcca tgcgaaaatt acaactggca
     6061 gagttcgcca tctctaattt atatgtagat acggtcaatg aaaacaaact cgttgaatcg
     6121 gccatcatag aaatgctggc acaactcgac cctcattcca cctattcgga tgccgaagag
     6181 gtgaagaaaa tgaatgaacc gctccaaggc aatttcgaag ggataggtgt acagtttcag
     6241 atgatcgaag atacgctgct catcgtacaa ccggtgagta atggcccgtc cgaaaaggta
     6301 ggtatcctgg caggagaccg tatcatcgcg gtgaatgaca cagccatagc aggcgtaaaa
     6361 atgggaacag aagaaatcat gggacgcctg cggggcccca aagattcgaa agtaaacctg
     6421 accattatcc gcagaggtgt gaaagaaccg cttttattta atgtaaaacg agataaaatt
     6481 ccaatcctca gcctggatgc cgcttatatg attcagccta aaataggata catccgtatc
     6541 aaccgttttg gagcaactac cgccgaagag tttttaaaag ccctgaaaga gttgcagaaa
     6601 aaagggatga aagacctgat tctggacctg caaggcaacg gaggaggtta tctgaatgcc
     6661 gccatcgatc tggcaaacga gttcctggga caaaaagaac tgattgtcta cacagaagga
     6721 cgttctgcac aacgcagtga gttttttgcc aaaggcaacg gaaacttccg taacggacgt
     6781 ctggtggtat tggtagacga atattcggct tcggcaagtg agattgtgac tggtgccatt
     6841 caggattggg acagaggagt ggtggtagga cgccgttctt tcggtaaagg actggttcaa
     6901 cgcccgatcg accttccgga cggttctatg atccgcctga ccattgcccg ctactataca
     6961 cctgcaggac gttgcataca aaagccttat gacagcagca tcaacgaaaa accgggaaaa
     7021 ggaaaaagca gtgaaagcag catcgaaaaa tacaaccagg atctgatcga ccggtataat
     7081 catggcgaaa tggtcagtgc agacagcatc cacttcccgg actcactgaa atgccagact
     7141 aaaaaactgg gacgtacggt ttatggtgga ggaggtatca tgccggacta cttcgttccg
     7201 gtagacacaa cgctgtatac tgactatcac cgtaacctgg tagccaaagg agtagtcatt
     7261 aaaaccacaa tgaacttcat tgaaaagaac cgaaaggctt tattggataa atataagaca
     7321 ttcgagaaat tcaatgaaaa gtttgaaatc gacgaccagc tattgaacta cctgagagaa
     7381 gctgccgata aagaaaagat tgaattcaac gaggagcagt acaacaaagc cctgccactg
     7441 attaaagctc agctgaaagc tttgatagcc cgtgacttat gggatatgaa tgaatatttc
     7501 caagtaatga atgccaccaa taagagtgtg gagcgggcac tggaaatctt aaatgacaaa
     7561 gagtacgaaa agatattgaa ataacgtttc tataacggaa aacgatatac ggtgaatgac
     7621 gaacagacta tgcttcctgc agcctgtttg tcattcaccg tatgtcgtca ataacttatt
     7681 gtaaccttct tcttctcacc gaacaaccac ttgttaagcc agcgattcac ataaatattg
     7741 gctaccgcac aaccggcccc tatcacagct cctgctgcta catccgacgg gtaatgtact
     7801 ccttcattca ttcttgagaa tcccacagaa catgcccaga aagcagatgg agctatcaca
     7861 taccatttag gataacggat actcaaagaa gtagccagtg aaaaggctgc tgccgtatga
     7921 ccggaaggaa acgaaggact cgattcatga ctacgtgcat ctacccgatc cggataacgg
     7981 tcgtagggac gctcacggtc aaaagcatat ttcataccat acgtaatcac gactgcctca
     8041 gccacactcg taccgatgta aatggcatct ttcagcagct ctttatcttt atcgatacct
     8101 gcatatacag ccatcgccac cggtacacct accgcaatat aaggtgccga tttagaaaag
     8161 gctttgctat aattcctcgc aaacttacta tcaagactgt ttattttatg taacgtattg
     8221 atatcccagt tctgagcata tccccctacc gaagaaagca cacaaaaaca aataagcaca
     8281 aatttcttca tttttctact aatttactat tttgcagcaa agatagatta aaaagacaga
     8341 gttttcgcaa aaaaaaccta tctttgttcc ctaagtatta tttaccctga cacctaactt
     8401 taattcatgg ccagagaaac tcaatgtaat agacagacag attgtgcgca atgtcccaaa
     8461 gctacagaag gcatacttgt tcaccggaag tttcccaaag gacaacattt tccgcccgac
     8521 aaatgcacac aaaattgtat cctgtttata ctacaaggag aattactggt caacagtgaa
     8581 gagtatcccg gcaccacatt acgtgaagga caatttattc tccagtccat cggctccaaa
     8641 ttagaattac tggcactgac agacgtaaat tatgtagtgt actggttcaa cgaaccaccc
     8701 ctgatctgtg aacagcgcta tcatgagatc ctgcaacaat cagaagctcc gctaacttat
     8761 acaccattgg ttatgacaca acgcataacc aacttcatga aagatatttg tgattacctc
     8821 ggtgaacaga tgccttgcgg cgcattcatc gatctgaaat gtcaggaact gatgtatctg
     8881 atcatctgtt attacccgat accccagttg agcaagtttt tctatcccat cagcagctat
     8941 acggaaagtt tccaatattt cgtcatgcag aattacgaaa aggtgaaaaa cgtagaggag
     9001 tttgcacacc tgggaggcta taccactacc acttttcgcc gtttattcaa gaacatgtat
     9061 ggcgtacctg tatacgaatg gattctgagc aagaaaagag aaggcatcct ggaagacctc
     9121 cagcatacca aacaacggat caccgagatc agtaatcgtt acggattcga ctctttatca
     9181 cattttgcac atttctgcaa agcttccttt ggagactctc cacgtgccct tcgtacacgt
     9241 gcagccagag gtgaaaaaat tactgcttta aaaacagaat agaaaccgct ctatttaccc
     9301 gataacgggc aaagcttcat ccgaatcccc ttctcattct tcggatcagt cggatacttc
     9361 tcccacgtaa atggatttca atcttccacc ctccggacaa gagctggaat acaacacatc
     9421 atgctgatat ccaaatgtat ataactatat ttctatccat ttatatcact taaagtattt
     9481 tatttttctt gctatcttta gtgaaaatgg tcttttcttt acctcgtcct gcatatctgt
     9541 gcccatgagc ccagataaca aggctcacat aaacatatca gaaggtacag taatactctt
     9601 atttacaaag tattataaat gatgtccatt tgacttgttt tcttcttaat tcatgcacag
     9661 aaaagagaat tagaggaaac ctcggaaaac ggccaattaa atataagcat gataacgact
     9721 ccaaaagcta acttcttaaa gacaaagatt ttactattct aacagattca caacaaatcc
     9781 tttatacccc taaccgatcg tcccgtttac cccatcctct ccggacattc aggattaaag
     9841 aattatttct ttaattcttt ggttaatcaa tgtatttcgt gtacttttgc acaatgagaa
     9901 agaaggctcg taaaacagaa attatagttc taacaattaa ataatttaaa atcaatcatt
     9961 tatgtggtta agtaattcat ctgtaggaag gaaagtggtg atgagcgtta ccggtatcgc
    10021 ccttgtcctg tttctaacgt ttcacatggc gatgaacctt gttgcgatca tctcggctga
    10081 gggttacaac ttggtttgtg agttcctggg agcaaactgg tatgcgttgg tagctacgct
    10141 gggcctggct gccctcttcg tgattcacat tatctacgct ttctggctga caatacagaa
    10201 tcgcgcagca cgtggtagcg aacgttacgc cgtagttgac aaacctaaaa ccgtggaatg
    10261 ggcatcacaa aacatgttgg tgctgggtat catcgttatc ttaggtttgg gccttcacct
    10321 ctttaacttc tgggctaaaa tgcagttacc tgaattggtg cacaacatgg gaggagtagc
    10381 agacacaact tatgctgctg atggtgttta tcacatcatg aacactttct ctaaccctgt
    10441 atatgtagtg ctgtacctcg tttggctggg cgccctttgg ttccacctga ctcatggttt
    10501 ctggagctct atgcaatctt tgggctggaa caacaagatt tggatcaacc gctggaaatg
    10561 catctccaac atctattcaa ccatcgttgt tgtatgcttt gctctggtag tagtcgtatt
    10621 cttcgttaaa tcgttggcat gcggtgcttg ctaaattgta aattgtaaat gattaaattg
    10681 taaatagcat tatgactaag atagattcaa aaattcctga aggccagctc gccgaaaaat
    10741 ggagtaacta taaggctcat caaaaacttg ttaaccctgc caacaaacgt cgccttgaca
    10801 ttatcgttgt aggtaccgga cttgccggag catctgctgc cgcttctcta ggcgaaatgg
    10861 gtttcagagt attcaatttc tgtattcagg attcaccccg ccgtgctcac tctattgcag
    10921 cacagggtgg tatcaacgca gctaaaaact atcaaaatga tggtgactcg gtttaccgtc
    10981 ttttctacga tacaatcaaa ggcggtgact accgtgcacg cgaagccaac gtttaccgtc
    11041 tggctgaggt atcaaacgct atcatcgacc aatgcgtagc acagggtgta cctttcgcac
    11101 gcgattacgg tggcacactt gacaaccgtt cattcggtgg tgcacaggta tcccgtacgt
    11161 tctatgcccg cggccagacc ggacagcagc tgttgctggg cgcttattca gcattgagcc
    11221 gtcaggtaca aaaaggtact gttaaacttt acactcgtta cgaaatgctc gacctcgttg
    11281 taattgaagg acgtgcgcgc ggtatcattg cccgtaacct cgtaactggt gaaatcgaac
    11341 gtttcgctgc tcacgctgta gttatcggta caggtggtta cggaaacgca ttcttccttt
    11401 ctaccaacgc tatgggttcc aacggttcag ttgccatcca gtgctataag aaaggtgctt
    11461 attttgctaa tccttgtttc gctcagattc acccgacttg tatccccgta cacggtgaca
    11521 agcagtctaa gctgacattg atgtctgaat cacttcgtaa cgacggtcgc atctgggttc
    11581 cgaagaagat tgaagatgcc aaagcattgc aggcaggcac taaaaagccg accgaaattc
    11641 ctgatgaaga ccgtgacttc tatttggaac gccgttaccc ggcattcggt aaccttgttc
    11701 cgcgtgacgt tgcttcacgt gcagccaaag aacgttgtga tgccggtttc ggtgtgaaca
    11761 ataccggttt ggccgtcttc ctcgatttca aatatgctat cgatcgtctg ggtgaggacg
    11821 tggttcgtgc ccgttatggt aacctcttcg acatgtacga agaaatcact gacgagaacc
    11881 cgtacaagac tccgatgatg atattccccg ctatccacta caccatgggt ggtatctggg
    11941 ttgattatga attgatgact tctatcccgg gtctgttcgc tatcggtgaa gccaacttct
    12001 ccgaccacgg tgctaaccgc ttgggtgcat ctgcattgat gcagggtctg gctgacggat
    12061 acttcgtatt gccttacacc atccagaact acctggccga tcagattcag gttccgcgct
    12121 tctctaccga cctgccggaa tttgctgcag ccgaaaagga agtgaaagat aagatccaga
    12181 agatcaaagc cgtaaacgga aaacactctg ttgactctat ccacaagaaa ctgggtcaca
    12241 tcatgtggga cttcgtaggt atggcccgta caaaagaatc tctgcagaaa gccctgacag
    12301 gcattgaaga ggtgaagaaa gatttctgga ccaacgttcg catcccgggt gatgtaaacg
    12361 aactgaacgt agaactggaa aaagcacttc gtctgatcga cttcattgaa gtaggtatgc
    12421 tgatggctcg cgacggtttg aaccgtgaag aatcttgcgg tggacacttc cgtaccgaat
    12481 accaaacccc ggaaggtgaa gcgttacgtg acgataagaa cttctcatac gtagcttgct
    12541 ggaaatacac cggtgaaaat tcagaaccgg agttgatcaa ggaagatttg aactaccagt
    12601 tcgtaaaagt tcagactcgt aactacaagt cataattcgg ctaatcaatt aaaggaaaac
    12661 aaaaatggat aaaaatatat cattcacact gaaggtatgg cgccagaaag gcccgaaagc
    12721 aaaaggtgct tttgaaacat atcaaatgaa agatatcccg ggcgatacgt cgttcctcga
    12781 aatgctggat atcctgaacg aacagattat taatgacggt ggcgaaccta tcgtattcga
    12841 ccatgactgc cgcgaaggta tctgcggtat gtgttctctt tacatcaacg gacacccgca
    12901 cggacctgcg acaggtgcta ctacctgcca gatgtatatg cgtcgcttca aagatggaga
    12961 caccatcaca gttgaacctt ggcgttctgc cggtttcccg gtaatccgtg acttgatggt
    13021 tgaccgttcg gcttatgaca agatcatgca ggccggtggt tacgtaagcg taaacacagg
    13081 tgctcctcaa gatgccaacg ctatccttat ctctaaggat atcgccgacg aggctatgga
    13141 tgccgctgca tgtatcggtt gcggtgcttg tgtagctgct tgtaagaatg gttctgccat
    13201 gttgttcgta tcagctaagg tcagccagct gaacctcctt ccacaaggaa aagtagaagc
    13261 agcacgccgt gcaaaagcta tgctttctaa gatggacgaa ctgggattcg gtaactgtac
    13321 aaacacacgt gcttgtgaag cagagtgtcc gaagaacatt tcaatcagca acatcgctcg
    13381 tttgaaccgc gatttcatca tcgcaaaact gaaagactaa gcacaactta gcatttgatt
    13441 aataagtagg aaaattcccc accggtatcg gtggggaatt tttgtatatg gagagcagtg
    13501 ttatctctta cggtgcttac gataccagat gataaagccg gtcacaggaa gtgaagcacc
    13561 cgtcaggctc gcaaggaaca ttataatttt accaggaagc ccccagatgc gcccgtcatg
    13621 aatctccaga ttcatacgac ggaacttatc ggcgggagag gcctcggtat atttaccggc
    13681 ataaggaccg gctcctttca aagaaaccag tgtataccgg tcaaaaaaca aattatcggt
    13741 acggtagtaa gaccctcttt tatgtacaac actgacccgg taaacaccat cggcttgtcc
    13801 gggtaaagca aaataaaagg tcttggcagc aggttcttca agccgtagct gagtataaag
    13861 tctgtccaaa gggtttgtca cacgattgac aacctgcaat gtatcggata ccggtaaaac
    13921 gtagggcttc aactcttcac cacccgaagt gatgctgtac acgcctctgc taaaccaatt
    13981 caggctaaat atcaatccgg taaaacataa tacggccagc accaatgcag cataaaaacc
    14041 cgcaacatta tgcaggtcga agttaagcct tgaaaaggta aaggggcgtt tcagagtcaa
    14101 ccgttgcaca agtgccttgc gcgtccagct tctgggccac caaagtatca ctcccgttat
    14161 cagggtgatg aggaaaatca atacactgta accaacaatc ggactcccga tctccctggg
    14221 gagccataaa gtgcgatgcc cgctaagcac caaccggaag aaatcgaaat caccgttatg
    14281 attcactacc gacttcaata cctgtccgct atacggattg ataaaaacag tactcatccc
    14341 tgcttccggc tgatagtagt ccacccaggc cgcatccgat ctttcaccgt aagtgatggc
    14401 tgtggccgaa gctcctccca tgacagaatc cgctatcgca agtaagcggg aaggcggcaa
    14461 aaactctttc tccaatggag ctacaaagcg ccaaggttgt gtggcatcgg taatttcgtc
    14521 tttaaatgca tacatgcagc cggtgatgca gactatgaat accacaatac ccgaaagcaa
    14581 tccaagccat aaatgaagtt tcgcacaagc cttccgaaaa gtcttattca tctcctatca
    14641 atccagacgg aagaaaccgc cgacaaacgt ggttgaaact ttagctcccc tgaccgcagt
    14701 agccgcctga ggatctacct gataaatgta agtcccctct gaagtagtga ccggacgata
    14761 aacataacct ccgtctacca gagcggcaaa acgccgtccg ccatctccgt tatgcaccgg
    14821 aatctcttta atgtcacgta ccgttttatt attaagatcg ataatgcagc atttcaaact
    14881 cttatctccc caacggtcgg cggatgtctg cggactgatg gtgctgacct cggcaaatac
    14941 cagaccatta ccgatatatt tgatatgggc aggtttcaat c
//
