LOCUS       gnlProkkaMEDCLNLC_254   3925 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MEDCLNLC_254.
ACCESSION   gnlProkkaMEDCLNLC_254
VERSION     gnlProkkaMEDCLNLC_254
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 19:33:35
            Original ID  :: gnl|Prokka|MEDCLNLC_254
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3925
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3925
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1623:3925]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1624..3925
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..3925
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3925
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             3..1673
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg210_1"
                     /sec_met_domain="Peptidase_S41 (E-value: 2.3e-15, bitscore:
                     44.3, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSEINLYTDSIFKEKKRIDSFVPTVFDANARLFYLCKIWGFIKY
                     YREDARLSVSQMDNLLLANIPRVKRADSKGKYCAILDSLIEYPAISQTKNKNPYPDLND
                     YALINNEWMDDTICLDYRIKKKLEAMFYSHSGRGNRFVFNKSIGNIALIDELEYASFPK
                     RDMRLVGLFQYWNLINYFYVYKNSIEGDWDRILYESIPLFEKADLPKKYHLEIYRLTNR
                     LRDTHASYPATIDGLVFGPYRPNFRMSLINDTFVINQIRIPAYDKGAFEIGDIVLKVDG
                     RDIHQLADSLKEFVCGGNYWSNQMFICNAILSQYDSATVFTLLRDGETLRTKSDNYSAY
                     DLFQKERLIDRNNEKLPLYHWVNDSIAYLNLRSASVDNIYDNYDAIKTASAIILDLRSY
                     PYTDIISPLTNMFVPPNSFFAYSTYSDTRFPGMLRYHRSSSNKIGSVNYYKGRIIILVN
                     EWTRSFSEYLTMALQVNPRSITVGNSTSGSDGNVSLFTFPGKVLTTYSGIGIYYPDFSP
                     TQRVGVRIDCIAEPSIQSIKDRIDVAYERAVIIAKGGTN"
     CDS             1624..2832
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     235.8; E-value: 1.3e-71)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_2"
                     /sec_met_domain="LANC_like (E-value: 6.1e-51, bitscore:
                     160.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRMKGLLLSQKVELTRLLQLKLDDIIQYLLNVNDEHCTSPGLLT
                     GNAGIAVLLFHYSKYKEDELYADKAMEFLSRSVDGMNDYFYPAFCGGISGICSAVLHLV
                     NEGFIDQENIELIEKFDNYLCEQALFESSNNYFDFLHGSIGVSNYLLRRSAKIGVLEVL
                     KQVVEILNYSKIIVNDTYTWEYKIGNKYNIGLAHGMSGTSLFLSNACKLGICDPVISQL
                     LEKSTSFILSQEIKNNNSISLFPTFALPQYTFCQYPVESRLGWCYGDLGVALALWKYSQ
                     VTKNTVVGNKAIEIFKFSANRKDLEDNYVIDASICHGTAGIALIFKKMYQETHLDIFRE
                     TSLYWLSETLNMSKYEDGIVGYKSDGEKKSLDLLNGVAGIGLVILSFLSEQDMFWEDLL
                     LLD"
     CDS             2834..3925
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     265.4; E-value: 1.5e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_3"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-78, bitscore:
                     252.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.7e-12,
                     bitscore: 35.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRCFNDFVLRTPLCYFDCVRDNWIVKVQDKLVLESIYLASPILY
                     DELCKLLDGSIDKGKEYNRIRYSIERYLCRMMTRCTPFGLFAGCSIGEIGSETSIQVDN
                     SLKRKTRLDMYYLSLLYNTLLRHSSISEGIYYYPNNSLYRLKHKYRYVECFHTDGNRKY
                     QLQEIDSTSYLNKILKLSSNGIKLNELIASLVCDEITNEEARHYVHELINSQILVGELY
                     QSLTGDDYFKRVISLLESTNCEVSLLNNLKGLKRRLDSMDLNESVEISTYAEIINNIKL
                     INVPYEKQYLFQVDMVKNLSQSILGEKVIVELKSTMEFLNKLTPLRQNEVLKKFQEDFF
                     YRYEEREVPLMEVLDPELGLGYPS"
ORIGIN
        1 ggtttagctc agaaataaat ttatatactg attctatatt taaagaaaaa aaaagaatag
       61 atagctttgt gccaacagtc tttgatgcta atgcccgctt gttttatttg tgtaaaattt
      121 ggggatttat aaagtattac cgtgaagatg cccgtctttc tgttagtcaa atggataacc
      181 tgttacttgc taatattccc agggtgaaaa gggcggattc taagggtaaa tattgtgcaa
      241 tattggatag tctgattgaa tacccagcga tttctcaaac gaaaaataaa aatccatatc
      301 cagatttaaa tgattatgcc ttaataaata acgaatggat ggatgatact atatgtctcg
      361 attatagaat taagaaaaaa cttgaagcta tgttttattc tcactccgga cgtgggaatc
      421 gctttgtttt taataaatct atcggtaaca ttgccttaat tgatgaattg gaatatgcct
      481 ctttccctaa aagagatatg cgtttggttg gactctttca atattggaat ttgataaact
      541 atttttatgt ttataaaaat agtattgaag gtgactggga ccgaatttta tatgagtcta
      601 taccactttt cgaaaaagcg gatttgccca agaaatatca tttggaaata tatcgattaa
      661 ccaatcggct acgtgacacc catgcttctt acccggcaac aattgatgga cttgtatttg
      721 gtccatatcg acctaatttc agaatgagtt tgattaatga tacatttgta atcaatcaaa
      781 tccggattcc ggcttacgat aaaggtgctt ttgaaatcgg tgatattgtt ttgaaagttg
      841 acggacggga tattcatcag ttagccgata gcctaaagga atttgtttgt ggaggaaact
      901 attggtctaa ccaaatgttt atttgtaatg ctattttgtc tcaatatgat tctgctactg
      961 tattcacgtt gcttagagat ggggagactt taagaactaa atcagacaac tattctgcat
     1021 acgatttatt tcaaaaagaa aggctaattg ataggaataa tgaaaagctt ccattgtatc
     1081 attgggtaaa tgatagtatt gcatatttga atttacgttc cgcttctgtt gataatattt
     1141 atgataatta tgatgccatt aaaactgcat ctgccattat tctagatttg agatcttatc
     1201 cttataccga tataatttcg ccattaacta atatgtttgt tcctcctaac tcattttttg
     1261 cctattcaac atattcggat actcgttttc caggtatgtt gaggtatcac cgatcttctt
     1321 ccaacaaaat aggtagtgtg aactattata aaggtcgaat tataatttta gtcaatgaat
     1381 ggacacgaag tttttctgaa tatttaacga tggctttaca agttaatccg cgttcaataa
     1441 cggttggcaa ttcaacttcg gggtctgatg gcaatgtttc actttttaca tttcctggaa
     1501 aggtgctaac tacttattct gggataggga tttattatcc ggatttttct ccaactcaac
     1561 gagttggagt acgtattgat tgcattgcag aacctagtat tcaaagtatt aaagatagaa
     1621 ttgatgttgc gtatgaaagg gctgttatta tcgcaaaagg tggaactaac tagacttttg
     1681 caattaaaac ttgatgatat aattcaatat ttgcttaatg ttaacgacga acattgtaca
     1741 tccccaggac tattgacagg taatgcaggg atagctgtcc ttctatttca ttattcaaag
     1801 tataaagaag acgaattata tgcagataaa gctatggagt ttttatctcg ctctgtagat
     1861 ggtatgaacg attattttta tcctgctttt tgcggtggta tcagtggaat ttgtagtgcc
     1921 gttttgcatt tggttaatga aggctttata gatcaagaga atattgaatt aattgaaaaa
     1981 tttgataatt acttgtgcga acaagctttg tttgaatctt caaataatta ttttgacttt
     2041 ttacatggct ctataggagt atctaattat ttgttgcgta gatcggctaa aataggtgtt
     2101 ttagaagtgc ttaagcaggt tgttgaaata ttgaattata gtaagataat tgtgaatgat
     2161 acatatacct gggaatataa aattggtaat aaatataata tcggattagc tcatgggatg
     2221 tctggaacca gtctgttttt atcgaatgcg tgtaagttgg ggatatgtga tccagtaatt
     2281 tctcagttgt tggaaaagag tacatcgttt attctgtctc aagaaataaa gaataataat
     2341 agtatatcat tatttcctac ttttgcttta cctcaatata ctttttgtca atatccggtt
     2401 gaaagtcgac ttggttggtg ttatggtgat ctaggtgttg ctttagctct ttggaaatat
     2461 tctcaggtta caaaaaatac tgttgtaggg aataaggcaa ttgagatttt taagttttcg
     2521 gcaaatcgaa aagacttaga agataactat gtaattgatg cgagtatatg tcatggtact
     2581 gctggaatag ccttaatctt taaaaaaatg tatcaagaaa ctcatttgga tatttttagg
     2641 gaaacttcat tatattggtt aagtgaaact ttaaatatgt caaagtatga agatggtatt
     2701 gttggttata aatcagacgg agaaaaaaaa tctttggatt tattgaatgg tgttgcaggc
     2761 ataggcttgg ttatattatc ctttttatca gaacaggata tgttttggga agatttactt
     2821 ttattagatt gaaatgtata gatgttttaa tgattttgtg ttgcgtactc ctttatgcta
     2881 ttttgattgt gtgagggata attggattgt aaaagtacag gacaagttag ttttggagtc
     2941 aatatattta gcatcgccaa ttctttatga cgaattatgt aagttgttgg atggtagtat
     3001 cgataaaggg aaagaataca atcggatcag atattctata gaacgttatt tatgtcgaat
     3061 gatgactcgt tgtactcctt ttggtttatt tgcaggctgt agtataggag agattggaag
     3121 tgagacaagt attcaagtag acaattcttt gaaacggaaa acaagattgg atatgtatta
     3181 tttgtctttg ttatataaca ctttgctgag acacagctct atttctgaag gtatttatta
     3241 ttatcctaat aatagtttat atcgtttaaa gcataaatat cgttatgtag aatgtttcca
     3301 tacggatgga aatcgtaaat atcaattgca agaaatagat agtacctctt atttgaataa
     3361 aatcttgaaa ttatcttcta atggaattaa gttgaatgaa cttattgcga gtctggtgtg
     3421 tgatgaaata acaaatgaag aggctcggca ctatgtacat gagttgatta attcgcaaat
     3481 acttgttggg gaactatatc aatcattaac cggtgatgac tattttaaac gtgttattag
     3541 tctacttgaa tcaacgaatt gcgaagtttc cttgttaaat aacctcaaag gtttaaaaag
     3601 gcgactggat tcaatggatt tgaatgagag tgtggaaatc agcacatatg ccgagattat
     3661 taataatata aaattgataa atgtacctta tgaaaaacaa tatcttttcc aagttgatat
     3721 ggtaaagaat ctatcgcagt ctatcttggg agagaaagta attgtagaat taaaatcaac
     3781 tatggagttt cttaataaac taactccttt acgtcagaat gaggtgctga agaagttcca
     3841 agaagacttt ttttacagat atgaagaaag agaagttcct ttaatggaag tattagatcc
     3901 ggagttgggc ttagggtatc catct
//
