LOCUS       c00065_gnlPro..        16008 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCCMOJGE_66.
ACCESSION   c00065_gnlPro..
VERSION     c00065_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 21:08:18
            Original ID  :: gnl|Prokka|MCCMOJGE_66
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16008
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16008
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[907:6008]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      908..6008
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..16008
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16008
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..703)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_1"
                     /sec_met_domain="Epimerase (E-value: 1.2e-43, bitscore:
                     142.4, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSNADVVDN
                     IEKVSGIRPVFEKLDCLDFDGLDAVFNKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGIEGIVFSSSCTVYGEPDELPVTENAPIKKATSPYGNTKQINEEIV
                     RDTVASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIR"
     CDS             complement(908..1480)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_2"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.1e-62, bitscore:
                     204.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVDTALGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLQYLQTITFILVIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQTSLVKIP
                     EGMKGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(1494..2081)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_3"
                     /sec_met_domain="Rnf-Nqr (E-value: 4.9e-70, bitscore:
                     228.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVLMNGIVKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNALSSMFDGIGMGLGFTIALTLLGAVREFLGTGKVFNLSIIP
                     EEYGMLVFVLAPGAFIALGYLIALINSLKKAN"
     CDS             complement(2099..2767)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_4"
                     /sec_met_domain="FMN_bind (E-value: 1.9e-23, bitscore:
                     76.1, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLESSLKNMLLVLTGVTAISVALLAYVNELTKGPIAEANAKTL
                     NEALKEVLPEFTNNPVAECDTVFSEKDGKKIVDFIIYPAKNGDQWVGTAVEAKSMGFGG
                     ELKVLVGFDAEGKIYNYSLLSHAETPGLGSKAADWFKEGNKGSIKGMNPGEQPLTVSKD
                     GGQVDAITASTITSRAFLNAVNAAYGAYKGDGGANGTTGASQKAVQKSETAIVDSVVIK
                     "
     CDS             complement(2764..3756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_5"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 8e-119, bitscore:
                     389.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFIVSLVYFGLGA
                     LIVTATSVIACLFFEWAIGKFLLKKETTTICDGSAVITGVLLAFNLPSNLPVWIIILGA
                     LFAIGVGKMSFGGLGNNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTAATPL
                     ALMKQAIHGDVSAFGQLPDAWSLFIGNNGGCLGEVSAAALILGLLYMLWKRIITWHIPV
                     SILVTVFVFSGIMHLANPEAYVSPVIQLLSGGLMLGAIFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(3762..5099)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-08, bitscore: 28.7,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 9.5e-16, bitscore: 50.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.3e-50, bitscore:
                     163.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1e-30, bitscore: 98.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIVTAEVPAKAVILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEANGFVSAAIHSSVSGKVAKIDSIVDASGYAKPAIFIDVDGDE
                     WEESIDRSPELVKECELTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVAILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSVAQPSNFLARIGTPMQQLIDACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNRKEAKRGEVQNCIRCAKCVSACPMGLEPYLLSALAENTEFERM
                     ESERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(5136..6008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 36.6; E-value:
                     1.8e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_7"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-11, bitscore: 38.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3e-08, bitscore: 26.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.5e-08, bitscore: 27.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 7.2e-08, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 2.9e-08, bitscore: 27.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 3e-10, bitscore: 32.8,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.6e-06, bitscore: 19.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAVLYVASKKFAVYEDPRIAQVSEVLP
                     QANCGGCGYPGCSGFADACVKAGSLEGKFCPVGGQPVMSQVASILGLDAGTAEPMVAVV
                     RCNGTCTNRPRTNMYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACVKACPKAIIELRAKGKKSRRVYVSCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDYNKCKSCRKCVEVCPQHTIIELNFPPRKPKEETPV
                     AEAAKTAEA"
     CDS             complement(6014..6433)
                     /locus_tag="ctg65_8"
                     /transl_table=11
                     /translation="MTNIITHQGIVENISGSQVFVRIIQTSACSTCSVKGHCSSADSKE
                     KVIEVTDTSSAWKIGDEVTIIGATSMGMQAVLLAFLIPLFLLIFGLFIFKTVLHSELYG
                     AFAALAVLIPYYYIIWLNRTRLKQKFSFTIKPINN"
     CDS             complement(6684..7088)
                     /locus_tag="ctg65_9"
                     /transl_table=11
                     /translation="MIKQDYLIRMIQEIISLIVNAILNKKKFRKDEWTEYDCLTRQILG
                     VSQEELLSMSLDEMIDCYEGDPNRMGKIELAAVTLLKVSDEVESDILQKSKLRQDGLSL
                     LKYVQKESSTFSIQRTNLIRMIEINESLKM"
     CDS             complement(7217..8650)
                     /locus_tag="ctg65_10"
                     /transl_table=11
                     /translation="MKTSHISTLAFAILFSSSVMAQKTNKPVSETVQSEVKADTLSETL
                     QQYLVLKLNLDGPKPKIDTVSILYNKYIGELEYLNDPSVPMRYIKTDPDYYRLFVPLTY
                     YNSPIAEYSTMHWKFKEPFVTPSLSSQLLPPYDTLQFSKAERASRLVNVALMDLYLNHP
                     NLVVNTEDHIMSRKLYHGDKKIEVPKTEVKSLFRADKVEDNVGEAEMVISKPNWWVTGG
                     NGSLQITQNYISDNWYKGGESNNAVMANLQLFANYNDREKVQFENLFEAKLGFNSSPSD
                     EYHKYLVNTDQLRLYSKLGIQAANNWYYTITGEFKTQFVKGYKANSEELVAAFLAPADV
                     IVSVGMDYKLKKKKFNLSVFMSPLTYNLRYIGNKNVDETKFGLDKGKCSKNDFGAQVQP
                     TISWTIIPSIVVDSRLNYLTNYKWVRVEWENTFNFVLNRYLSTKLFVHARFDDSAKPTT
                     GSSYFQLKELLSFGLNYKW"
     CDS             9034..10635
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_11"
                     /sec_met_domain="GATase (E-value: 8.7e-55, bitscore: 178.5,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGQNALCVHLTYVPFLSAAQELKTKPTQHSVKELQSLGVQPDILVLRTEHDLNTNL
                     RKKVALFCNVAENAVVQSIDASTIYEVPLLMQEQGLDETILQKMGLPVGERPPLGPWKD
                     FLNRRANATETVTIAMVGKYVELQDAYKSILESLSQAATYNDRKVKIEYVSSEHLTPDN
                     VDEQLGHVNGVVICPGFGSRGIEGKFVAAKYTREHNIPTFGICLGMQCMAIEFARNVLG
                     YADANSIEMDEKTKHNVIDIMEEQKAITNMGGTMRLGAYECVLKKDSKVYEAYKEEHIQ
                     ERHRHRYEFNNDYRKQFEEAGMKCVGINPESDLVEIVEIPTLKWYIGTQFHPEYSSTVL
                     HPHPLFVSFIKAAIDK"
     CDS             10684..12540
                     /locus_tag="ctg65_12"
                     /transl_table=11
                     /translation="MDKNTITGLVLIGILLVGFSFLSRPSEEQIAAQKRYYDSIAVVQQ
                     QEEALRAKTEAALANEKEETAADSASLFFNATKGKEAFTTIQNNLVEITLDNKGGRVYS
                     ALLKNYMGQDKKPVVLFNGSDASMNFNFYNKKGALQTKDFYFEAVNKTDSSVTMRLAAD
                     SASYIDFIYTLKPDNYLMSFVIKATGMDGKLAASTNYVDISWSQRARQIEKGYTYENRL
                     ADLTYKYTGDDVDNLSASKDDEKSVSERLDWIAFKNQFFSSVFIAEQDFEKTTVKSKME
                     KQGSGYIKDYSAEMSTFFDPTGKQPTDMYFYFGPNHYKTLTALDKGREEKWELNNLVYL
                     GWPLIRWINKWITINVFDWLSGWGLSMGIVLLLLTIMVKIVVFPATWKTYMSSAKMRVL
                     KPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSA
                     IELRQQSFLWADDLSTYDAFITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMQQQDTG
                     AQPQMAAMKWMMYLMPIMFLFVLNDYPSGLNYYYFISTLISVVTMIILRRTTDENKLLT
                     ELEAKKKDPKQMKKTGFAARLEAMQKQQEQLAKERANKQNKK"
     CDS             12629..13960
                     /locus_tag="ctg65_13"
                     /transl_table=11
                     /translation="MTTKYTYKEIWIIAYPILISLIMEQLIGMTDTAFLGRVGEVELGA
                     SAIAGVYYLAIFMMAFGFSIGAQILIARRNGEQQYQAIGPIFYQGVYFLLSLAVVAFTL
                     SLCFSPHILKKVISSEHIYDASISYINWRVFGFFFSFVGVMFRAFFVGTTQTKTLTLNS
                     VVMVLSNVVFNYILIFGKFGAPQLGIAGAAIGSSLAEMVSVIFFVIYTWKRIDCKKYAL
                     NHLPGFRPEMLKRILNVSFWTMIQNFFSLSTWFMFFLFVEHLGERALAITNIIRNVSGI
                     PFMVTMAFAATCGSLVSNLIGAGEIKCVPGTIRQHIRIGYIFVLPLVILFALFPNLILS
                     IYTDIPDLREASIPSLWVLCSAYLILVPANVYFQAVSGTGNTRTALGLELCVLAIYLIY
                     ITYMILYLRVDVAVCWTTEHLYGICILFLSYLYIKKGNWQKKQI"
ORIGIN
        1 cacggataca tgaaccgtca ggtgtatcat aatcatcacc gaagacactc aatttttcgc
       61 gaatcccgat agcagtctga gttaaatacg gaataagatt ttgaggtacg ccattaggaa
      121 gttctcctaa caatgctgtc ggatgagcac caatcggatt aaaataacgc agtaaaattg
      181 cattaatcgg agcaccggaa gctactgtat ctctaacaat ctcttcatta atctgtttgg
      241 tatttccata aggagaagta gctttcttta tcggagcatt ctctgttaca ggcaattcat
      301 ccggttcacc atatacagta catgaagaag agaatacaat gccctcaatg ccatgtttag
      361 gcattaattc aagcaagtta attaaagaaa cgaggttgtt gcgataataa agcaatggtt
      421 tttctacaga ctcacctact gccttgctgg ccgcaaagtg gataatcgct ttaatacctt
      481 tatatttatt gaacacggca tctaaaccgt caaaatccaa gcaatccagt ttctcgaaaa
      541 caggacgaat acctgatacc ttttcgatat tatctacgac atcagcattt gaattagata
      601 aattatcaat gatgattact tcgtatccac tgttttgcag ctctaccaca gtatgagagc
      661 cgatatatcc ggttccgcct gttactaaaa ttctttcttt cataacgtgt ataatggtta
      721 gttttttcgg tttacttgta aagtgtttgc aaatgtaaca aaattaattt agataaatgc
      781 acaaaaaacg aatattattt cataacgcaa acagggatta agacaaaata acagaaaaag
      841 cggcggaaga actaccccat cggtagccta tccgccgctc catccttcag ttgtttgtcg
      901 tcaggattta tacaactccg gagaatccca taaatgccat agccagcaat ccggctgtaa
      961 ttaaagcaat cggagtacct ttcattcctt cgggaatttt cacaagactc gtctgctcac
     1021 ggagtccggc gaaaagtacc agggccagac cgaaaccaat agcagtagag aatgcatata
     1081 caacacccgt cagtaggtca taatcttttt ggataacaag aattgccaca cccaagatac
     1141 aacaattcgt tgtaatcaag ggaaggaata cgcccaatgc ctgataaagt gcgggagaaa
     1201 ctttcttcag aataatttct accatctgca ccaatgcagc gataaccaag ataaacgtga
     1261 tagtctgcaa gtactgcaac ccgaaggcat cgagtacaaa cttctggatc aggaacgtta
     1321 cgatcgtagc aatggtaagc acgaaagcta ccgctgcact catacccaat gcagtatcca
     1381 ccttcttgga aacacccaag aaaggacaga ttcccagaaa ttgcgacaac acaatgttat
     1441 taacaaagat tgccgagata aatatcaata tatattccat aatcgtttat attttaattc
     1501 gctttcttaa ggctgttaat caacgcaatc agatatccca atgcgataaa cgcacccgga
     1561 gcaagcacaa agacaagcat accgtattct tccggaatga ttgacaagtt gaataccttg
     1621 cctgtaccca ggaactcacg aacagctccc agcaatgtaa gggcaattgt aaagcccaat
     1681 cccataccga ttccgtcgaa catagaagaa agtgcattat tcttggctgc aaatgcttct
     1741 gcacgtccca acacaatgca gttcacaaca atcaatggaa taaaaagtcc caatgtagcg
     1801 tacagtccgg gtacatatgc ttgcattacc atctgaagca aagtcacaaa agatgcaatg
     1861 actacaatga atgacggaat acgcaccatg tccggaatca agttctttat caatgaaatc
     1921 actacattgg aacagatcaa tacaaacata gtggcaagcc ccatgcccat accattaatg
     1981 gccgaggaag tcgtaccgag tgtaggacac ataccaagca ggagcacaaa tgtcggattc
     2041 tctttaacaa tcccattcat taatacttta aagttattca tatctttata ctcctttctt
     2101 atttaatgac tactgaatcg acaatcgcag tttcggactt ctgcacagct ttctgcgaag
     2161 caccggtcgt accattagca ccaccatcgc ctttataagc accataggca gcattcacag
     2221 cattcaaaaa tgcacgtgag gtgatagtag aagcagtaat ggcatctacc tgtccgccgt
     2281 ctttacttac agtcagcggt tgctcacccg gattcattcc cttaatgcta cctttgtttc
     2341 cttctttgaa ccagtcggcc gccttggaac caagtcccgg agtttcggca tgtgacaaca
     2401 aagaatagtt gtagatttta ccttcagcat caaaaccaac aagtactttc aattctccgc
     2461 caaatcccat cgacttggct tctactgctg ttcctaccca ttgatctccg tttttagccg
     2521 gataaatgat aaagtcaaca atcttcttgc catctttctc actaaacacg gtatcacact
     2581 ctgcgaccgg attatttgta aattcgggca aaacttcttt taaagcttca ttcaatgtct
     2641 tcgcattcgc ctctgcaatg ggacctttag tcaactcatt cacataagcc agcaaagcta
     2701 ccgagatagc tgttactccg gtgagtacca gcaacatatt tttcaatgat gattctaact
     2761 ttttcatttc ttcttcgcta cctccccaaa gcgttttggt ttgcaatacg tattgattag
     2821 cggagtgaat gcattcataa tcagaatagc aaacgacata ccttccggat atgcaccaaa
     2881 cagacggata acaaccgtca gcaaaccgat gcagacacca taaatcaaca tacctttttt
     2941 actcatcgga gaggtgacat agtctgttgc cataaagata gcacccagca tcagacctcc
     3001 cgaaagcaac tggatcaccg gagaaacata agcttcggga tttgccagat gcatgatacc
     3061 ggaaaataca aatacagtaa ccagaatgga tacagggata tgccatgtaa tgattctctt
     3121 ccataacata taaagaagac ccaaaatcag ggcagcagca ctcacttcac ccagacatcc
     3181 accattgtta ccaataaaca gactccaggc atcgggcagt tgaccaaagg ccgagacatc
     3241 accatgaata gcctgtttca tcaatgccaa aggagtggcg gcagtagtag catcggtata
     3301 agcagtcaac tgaccgacca ccggccagga agtcatctgt accgggaatg acaataacag
     3361 aaacacacgc cctgccagtg ccgggttaaa cggattgttc cccaagccgc caaatgacat
     3421 cttaccgaca ccaatagcaa acaaagcacc taaaataata atccatacag gtaagttaga
     3481 cggtagattg aacgccagca acactcccgt gatgacagca gaaccgtcac aaatagtagt
     3541 ggtttctttc ttcagcaaga acttaccgat tgcccattca aaaaacaaac aggctatcac
     3601 agaagtagct gtgacaatca gtgcacccag tccgaaatat acgagcgaaa cgataaaggc
     3661 aggaatcagc gcaatcagca caccgtacat attcttttgt acgctgtctc caccatgaac
     3721 gtgaggcgat aatgatacaa ttaatttatt ttccatactt attatttttt agcttgacgt
     3781 gcacgaatca tagctcctac tttcccctta cccagacgac agtagtcgag taacggacga
     3841 ttggcaggac aagtgaactg gcaagagcca cactcgatac aatccatgat tctttctgat
     3901 tccattcttt caaattctgt gttctcagcc aaagcggaaa gcagatacgg ctccagtccc
     3961 atcgggcagg cactcacaca ctttgcacaa cgaatgcagt tctgtacttc tccgcgtttt
     4021 gcctctttcc ggttcataat caaaattccg gaacttcctt tagcagtggg cacatcagta
     4081 ttaaccaatg ctttacccat catcggacca ccgccaatta tttttccggt atcctccggc
     4141 aaaccgccac aggcatcgat caactgctgc atcggagtac caatacgcgc caaaaagtta
     4201 gaaggctggg caacagactt accggtcacc gtaatgacac gctcaaacaa aggcttattt
     4261 ttctgtacag cttgatatac ggcaaatgca gtacctacat tctgcacaac tgctcctgta
     4321 gagataggta atgcgccgct tgcaacctgg cgctttgtaa tagcatcgat taactgcttc
     4381 tcaccccctt gaggatattt cactttcaaa ggaacaactt caataccggc ataactggat
     4441 gcgactttcg tcatcagttg gatagcatcg ggtttattgt tttcgatacc tataaaagcc
     4501 ttattgactt tcaccgcctt catcagaata gccaccccta ccattacctc ctcggcatgt
     4561 tccaacatca gttgatggtc ggctgtcaag taaggttcac actctacagc gttgataatc
     4621 acgcattctg ctttaaatga aggaggcgga caaagtttga cttgagttgg gaaacaagct
     4681 cctcccaaac caacaatgcc tgcatctgct atcttcttca caatctcttc cgaagtcaat
     4741 tcgcactctt ttaccaattc aggactacga tcgatagact cttcccattc atccccgtct
     4801 acatcaataa aaatagcagg tttagcataa ccgctcgcat cgacaataga gtcaatctta
     4861 gcgactttac cactgacaga agagtgaatg gctgccgaaa caaagccatt agcttcggct
     4921 attttagtgc ccaccttcac cacatcacct tttgccacaa taggcttagc aggcgcaccg
     4981 atatgctgcc ccagcagtat cacagctttt gccggaacct ctgccgtaac aataggttga
     5041 tgtgctgaga gtttattttc gtgtggatga acaccaccaa ttgaaaatgt cttcaacata
     5101 caattctgta ttttatctgt ttattactcg tttttttaag cttcggcagt tttggcagct
     5161 tcggcaacag gcgtttcctc tttaggttta cgaggaggga aattcaactc gatgatagtg
     5221 tgctgtggac aaacttcaac gcacttgcga caagacttac atttattgta atcgatgtaa
     5281 gcgagattgt tttcaagtgt aattgcctcg aacggacaag ttttgacaca cttaccacaa
     5341 ccgatgcaac ttaccgtaca ggctttgcgt gcgacagccc ctttgtcttt gttgacacaa
     5401 gatacatata cacgacgcga tttcttacct ttggcacgaa gctcgattat cgctttcgga
     5461 caggctttta cacaagctcc gcaagccgta cacttttctt catccacctc aggaagtcct
     5521 gtttccggat tcatgtgaat agcatcgaac tggcaggcag ccacacagtc gccacatccc
     5581 aaacatccat agctacagcc ggtctctccg ccataaagcg aagcagcaat agcacagctc
     5641 tttgcaccgt catacatatt tgtacgcgga cggttcgtgc aggttccgtt acatctaacc
     5701 actgcaacca tcggttctgc agttccggcg tccaatccga gaatagaggc aacctgagac
     5761 atcacaggct gtccacccac cggacaaaac ttaccttcca gcgaaccggc tttgacgcaa
     5821 gcatcggcaa atccgctgca acccggataa ccacatccac cgcagttagc ctgaggcaac
     5881 acttcggata cctgggcaat tcgtgggtct tcgtacacgg caaatttctt agaagcaaca
     5941 tacaatactg cagccaatac aagcgcaata gctcccaaag aaatcactgc aatcagaatc
     6001 aaattcataa tttttagtta tttattggtt ttatagtaaa agaaaatttt tgtttcaacc
     6061 gagttctgtt caaccatatt atataataat aaggaataag caccgccaaa gcagcaaatg
     6121 ccccatatag ttcactatga agaactgtct tgaaaatgaa aaggccaaag attaaaagaa
     6181 agagaggaat gagaaaagcc agaagaaccg cttgcatgcc catggaggtg gcaccaataa
     6241 tcgtcacctc gtcccctatc ttccatgcag acgaagtatc ggtaacttca attaccttct
     6301 ccttgctatc tgccgaagag caatgtccct tgacactgca agtcgagcaa gccgatgtct
     6361 ggatgatcct cacaaaaacc tgagaaccac ttatgttttc cacaatacct tgatgagtta
     6421 ttatattagt cattttgcaa actgcacatt acaaattgcg gcaaatttaa gcataagttt
     6481 gaaaattacg aagtatttga atgtttttta tagtgcaata tgaagtcttt ttaaagtaat
     6541 ttttgctcta tcaatcgggt atggatacag aaaaagcagg cttttcacct gctttactaa
     6601 gaaaatgtta tcatcttctg atatttttaa agaaattaga aacaaaaacc aattctttta
     6661 tcactttctg tttatttccc cttctacatt ttaagagatt cattaatctc aatcatccga
     6721 atcaaattcg tccgctgaat tgaaaaggta ctgctttctt tctgaacata ttttagcaag
     6781 gaaagcccat cctgacgtaa tttggacttt tgcaaaatat cagattccac ctcgtccgaa
     6841 actttcaaca aagtcacggc cgccaattct atcttcccca ttctattagg atctccttca
     6901 taacagtcaa tcatttcatc caggctcata cttaacaatt cctcttgaga aactcctaaa
     6961 atctgtctcg tcaggcaatc atattcagtc cattcatcct tacggaactt ctttttattc
     7021 aatatcgcat ttacaattaa cgaaatgatt tcctgaatca tccgtatcag atagtcttgt
     7081 ttaatcataa tatcctcttt ttgaattaga acttacttac cacggggaga attaacctca
     7141 ccggaaagaa gagagccgac tgaagattcc agtcggcccc tatttcatat atttacatta
     7201 tgtcaattat tcccgattac catttataat tcagaccaaa acttagcaac tccttcagct
     7261 ggaaataact gctgcctgta gtcggcttcg cactgtcgtc aaagcgtgca tgtacaaata
     7321 gtttagtaga aagataacgg ttcaatacaa agttgaaagt attctcccac tctacacgca
     7381 cccatttata gttcgtcaga tagttcaaac gggaatcgac tacaatagac ggaataatag
     7441 tccatgaaat agtaggttga acctgtgcac cgaagtcatt cttcgagcat ttgcctttat
     7501 ccaatccaaa cttggtttcg tccacgtttt tgttacctat ataacgaagg ttataagtca
     7561 acggagacat gaatacagaa agattgaatt ttttcttttt caacttatag tccataccga
     7621 cactgactat cacatctgca ggagcaagga aagcagccac caactcttca ctgttagcct
     7681 tatatccctt tacgaactgg gttttaaact ctcctgtaat agtatagtac caattattgg
     7741 cagcctgaat acctaattta gaatacaaac gcaactggtc ggtattaacc aggtatttat
     7801 gatattcgtc tgacggagaa gaattgaatc ctaatttagc ttcgaacaga ttttcaaact
     7861 gtactttctc acggtcattg tagttagcga acaactgcag attggccatt acggcattat
     7921 tgctctcacc tcccttgtac cagttgtccg aaatatagtt ctgggtaatc tgaagcgaac
     7981 cgttacctcc tgtcacccac caattgggct tggagatcac catttccgct tcacccacat
     8041 tgtcttccac cttatccgca cggaacaggc ttttcacttc tgttttcggg acttcaatct
     8101 tcttatcgcc atgatacaac ttacggctca tgatatgatc ttcggtatta acgactaaat
     8161 taggatggtt cagatataga tccatcaaag caacattcac cagccgggaa gctctctcag
     8221 ctttagaaaa ctgcaatgtg tcatacggcg gcaataattg cgaagaaaga gagggagtaa
     8281 caaaaggttc cttaaacttc cagtgcatgg tagaatattc cgcgatggga gagttataat
     8341 aagtcagcgg tacaaacagt cggtagtaat ccggatctgt cttaatataa cgcatgggta
     8401 cagaaggatc attaagatat tccaactctc ctatatactt attatataag atggacaccg
     8461 tatctatctt aggcttcgga ccatccagat tcagtttcag gacaaggtac tgttgaagcg
     8521 tctcggaaag tgtatctgct ttcacttcac tctgcactgt ttcagaaacc ggtttgttcg
     8581 tcttctgcgc catcactgac gaagaaaaca ggatcgcaaa tgctaatgtt gagatgtgac
     8641 tagtcttcat ttttataaca aatttggggc aaatttacat taaatagttt agattacata
     8701 aaatttgctc gattttaata ggaataacct atcaaatgaa tctatacaac aattcagctg
     8761 ttttattgga acgtgcgtta tctctcagaa caatacagat cgaactgaga accgccttcc
     8821 cccggctcga tagtgcaagt tgaataaagg cgtgcttata tgccggcaaa catgtgactg
     8881 tttgtcgttc aaacatttcg gtacccggaa ttgcattttt taataaattt gttttgtaga
     8941 aagcatccgt tcttccccat ttttttgtaa ttttgcggtt tttaagattc aaatcaaagg
     9001 atttagaaac aaattattaa aacagttata gctgtgggag aaacaaagta tattttcgtc
     9061 accggtggtg ttgcctcttc tttaggaaaa ggtatcattt catcttccat cggtaaattg
     9121 ctgcaagcaa gaggttataa agtaactatc cagaagtttg acccgtacat caacattgac
     9181 ccgggaacat tgaaccctta tgaacacgga gaatgctacg tgactgtaga cggccatgaa
     9241 gccgatcttg acttaggaca ctacgaacgt ttcctgggca tccagacaac gaaggccaac
     9301 aacatcacga caggccgtat ctataagagc gtcatcgata aagaacgccg tggagattat
     9361 ttggggaaaa ccattcaggt gattcctcat atcaccgatg aaatcaaacg taacgtcaag
     9421 ttactgggta acaagtataa gttcgacttt gtaatcacag aaattggcgg aacagtaggt
     9481 gatatcgaat ctttgcctta tctggaaagt attcgtcagt tgaaatggga actgggtcag
     9541 aatgccttgt gtgtacacct gacttatgta cctttcctgt ccgccgccca agagttaaaa
     9601 accaaaccga ctcaacattc cgtaaaagag ttgcaatcac tcggtgtaca gccggatatc
     9661 ctggtgctac gtaccgaaca tgacctgaat accaacttgc gcaagaaggt cgctctgttc
     9721 tgtaatgtag ccgaaaacgc agttgttcag tcaatcgacg cttcaactat ttatgaagta
     9781 cctctgttga tgcaagagca aggcctggac gaaaccatac tccaaaagat gggtctgcct
     9841 gtaggcgaac gtccgccgtt gggtccttgg aaagacttcc tgaaccgtcg tgccaatgca
     9901 actgaaacag taaccattgc aatggtaggt aaatatgttg aattgcagga tgcctacaaa
     9961 tctattctgg aatccttgtc acaagctgct acctacaatg accgcaaagt aaaaatagaa
    10021 tatgtatcat ccgaacatct gactccggac aatgtagacg aacaattggg acatgtaaac
    10081 ggagtagtta tctgtccggg attcggttca cgcggtatcg aaggtaagtt cgtagctgcc
    10141 aaatacaccc gcgaacacaa cattccgaca ttcggtatct gtctgggtat gcaatgtatg
    10201 gctatcgagt ttgcccgtaa tgtgttgggt tatgccgatg ccaactccat tgaaatggat
    10261 gaaaagacca agcacaacgt gatcgacatc atggaagagc agaaagccat caccaatatg
    10321 ggaggtacta tgcgtctggg agcttacgaa tgtgtattga agaaagactc taaggtatac
    10381 gaagcctaca aagaagaaca cattcaggag cgtcatcgcc accgctacga attcaacaac
    10441 gactatcgca aacaattcga agaggccggc atgaagtgtg taggtatcaa ccccgagtcc
    10501 gacttggtag aaattgtaga gattcctaca ttgaaatggt acatcggaac acagttccat
    10561 ccggaataca gcagtaccgt actacacccg catccgttgt tcgtgtcgtt catcaaggct
    10621 gcaatcgata agtaaagatc gttatcgtat agattattaa tcattaatca cttaaaaaag
    10681 agaatggata aaaacaccat cacaggcctc gttttaatag gtatattact ggtaggattc
    10741 agttttctga gccgtcccag cgaggagcaa atagccgctc aaaagcggta ttatgactct
    10801 atagccgtgg tacagcagca agaagaagca ctgagagcca aaaccgaagc tgcgctggct
    10861 aacgaaaaag aagaaacagc agccgactca gcatcgctct tcttcaatgc caccaaaggt
    10921 aaagaggcgt ttactactat ccagaataat ttggtagaaa tcactctgga taacaaaggc
    10981 ggccgtgttt actctgccct gttgaaaaac tacatgggac aggataagaa accggttgtg
    11041 ttgttcaacg gcagcgatgc ttccatgaac ttcaacttct ataacaagaa gggggccctc
    11101 cagacaaaag acttctattt tgaagcagtc aataaaacag atagcagtgt aacgatgcgt
    11161 ctagctgccg acagtgccag ctatatcgat ttcatttata cactgaaacc tgataactac
    11221 ctgatgagct ttgtgatcaa agctacggga atggacggaa aattggctgc cagcacaaac
    11281 tatgtggaca tctcatggtc acaacgtgcc cgccagatcg aaaagggata tacttacgaa
    11341 aaccgtttgg cagacctcac ctacaaatac accggtgatg atgtggataa cctttcggca
    11401 agtaaagacg acgaaaagtc cgtttcggag cgtctggact ggatcgcttt caagaatcag
    11461 ttcttctctt ccgtattcat cgcagaacag gatttcgaaa agactacggt taaatcgaaa
    11521 atggagaaac agggaagcgg ttacataaag gactattccg ccgagatgag tacgttcttt
    11581 gatccgaccg gcaaacaacc taccgatatg tatttctact tcggcccgaa ccactacaaa
    11641 acgttgactg cgttggataa gggacgtgaa gagaaatggg aacttaacaa cctggtatat
    11701 ctgggctggc cgctgattcg ttggattaac aaatggatca ccatcaacgt attcgactgg
    11761 ttgtccggct ggggattaag tatgggtatc gttctgttgt tactcaccat catggtgaaa
    11821 atagtcgttt tcccggcaac atggaagacc tatatgtcat cagccaaaat gcgggtgctg
    11881 aaaccgaaaa tcgatgaaat caacaagaaa taccccaaac aggaagatgc gatgaagaaa
    11941 cagcaggagg tgatgggatt gtacagccag tacggtgtaa gcccgatggg tggctgtctg
    12001 ccgatgttgt tgcaattccc tatcctgatg gcattgttca tgttcgtacc gagtgctatc
    12061 gaacttcgtc agcagagttt cctttgggcg gatgacttgt cgacttatga cgcattcatc
    12121 actttcccgt tccatattcc attcttgggt aatcacctca gtttgttctg cttgctgatg
    12181 actgttacca acatcctgaa tacgaagtac acaatgcaac agcaggatac gggtgcccag
    12241 ccgcaaatgg ctgcgatgaa gtggatgatg tacctgatgc cgatcatgtt cctcttcgtc
    12301 ttgaacgact atccttcggg attgaactat tactacttca tttcgactct gatcagtgta
    12361 gtaaccatga tcatactgcg ccggacaact gacgaaaaca aattgcttac cgaactggaa
    12421 gctaagaaga aagatccgaa acagatgaag aagaccggat ttgccgcacg cctggaagct
    12481 atgcaaaaac aacaggaaca attggcaaaa gaacgggcta ataagcagaa taagaaataa
    12541 gagatagaaa tcagcttaaa taccgaagag ccggacaagc agtgtatgtt tgtccggctt
    12601 tcttttcctt tattgaacag attacaacat gactactaaa tacacataca aagaaatatg
    12661 gattatcgcc taccccatcc tgatcagcct gatcatggaa cagctgatag gcatgaccga
    12721 cactgctttt ctgggacgtg tgggcgaagt cgaactggga gcctcggcca ttgccggtgt
    12781 atactatctg gctattttta tgatggcatt cggattcagt ataggtgcac aaatcctgat
    12841 tgcccgtcgt aacggtgaac agcaatacca ggctatcggg cccatctttt atcagggtgt
    12901 ctactttctg ctttcactcg cagtggtagc attcactctt tcgctgtgct tctcaccgca
    12961 catactgaaa aaggtcatta gctcggagca tatatacgat gcgtccatca gctacatcaa
    13021 ctggagggtc ttcggctttt tcttctcctt tgtcggggta atgtttcgtg cattcttcgt
    13081 gggtacaact cagaccaaaa ccctgacact gaactctgtg gtcatggtat tatccaatgt
    13141 ggtgttcaac tacatactga ttttcggtaa gttcggtgct ccacagttag gtatcgccgg
    13201 agccgccatc ggttcgtcac tggccgaaat ggtttcggtc atcttcttcg tcatctacac
    13261 ctggaaacgg atagactgta aaaagtatgc cttgaatcat ctgcccggat tccggccgga
    13321 gatgctgaaa cggatcctga acgtatcctt ttggacaatg attcagaact ttttctcact
    13381 gtccacttgg ttcatgttct tcctatttgt cgaacactta ggcgaacgtg cactggccat
    13441 aaccaatatc atccgtaacg tatcgggcat cccgtttatg gtcaccatgg catttgcagc
    13501 tacttgcggc tccctggtga gtaacctgat cggtgcgggc gaaatcaagt gtgttcccgg
    13561 aacgatccgc cagcacatcc gtatcggtta tattttcgtg ctgccgctgg ttatactctt
    13621 cgcactgttt cctaacctga tattgagtat ctatacggat attcccgatt tgcgggaggc
    13681 ctccatccct tctttatggg tactatgctc cgcttatctg atactcgtac ctgccaacgt
    13741 ctattttcag gcagtatccg gaacgggcaa cacacgtacg gcattgggat tggaactctg
    13801 tgtactggcc atttatctga tctatatcac ctatatgatt ctctatctga gagtggatgt
    13861 agccgtctgc tggactacgg aacatctgta cggaatctgt atcctgttcc tttcatacct
    13921 ttatataaag aaaggaaact ggcagaaaaa gcagatttga cctgattttt gcttatcttc
    13981 gcagcactat tatggaagag aacacaagta aattactaat tattaaaata actatgagac
    14041 aagtaaacct atttattatg tcggcagcaa tgatgttagc atcttgtggt ggaaccaaag
    14101 atgcaggcaa aacagatcag gcgctgatcg gtaaatccga tatcaagatc gaaggaaagc
    14161 ggatgactcc cgaagcgctt tgggcgatgg gacgtatcgg cggactggcc gtatcgcctg
    14221 acggaaagca aatagcctat actgtggctt attacagtgt ccccgagaac aagagcaacc
    14281 gggaagtttt tgtgatgaac gcggatggaa cggataatcg acagattacc cacactcctt
    14341 atcaggaaaa tgaagtgact tgggcggcag acggaagcaa gctgctcttc ctgagcaatg
    14401 acaacggcag cagccaactg tatgaaatga atccggacgg tagcggacgc aagcagatct
    14461 ccaagtatga cggagacatc gagggatatt ccatctcacc ggacggtaaa aaaatactct
    14521 tcatcgctca agtgaaaaca gtaaagagca cggctgataa ataccccgac ctggataaag
    14581 cgaccggaat catcatcacc gacctgatgt ataaacattg ggacgaatgg gtgaccaccg
    14641 ctccacatcc tttcatcgcc gactttgatg gcaaatcaat ctccaacatc atagatgtgc
    14701 tggaaggaga accttacgaa agcccgatga aaccttgggg aggtatcgaa caactggctt
    14761 ggaatacgac ttcggacaag gtggcttata cctgccgcaa aaaaacggga ctggcttatg
    14821 ccatatctac caactcggat atctatgtat atgacctgaa taccaagaaa acagtaaaca
    14881 tcaccgaagg tatgatgggt tatgatacaa acccgcaata ttctccggat ggaaaaagca
    14941 ttgcctggca aagcatggag cgcgacggtt acgaagctga ccagaaccgc ctcttcgtca
    15001 tgaacctgga aacgggcgag aaacgttttg taagtaaagc tttcgattcg aatgtagatg
    15061 cattcgtatg gagccgggat gccaagacga tctacttcac cggtgtatgg catggcgaga
    15121 cacaaattta ttcactcgat ctggctaacg attccgtacg ccccgtcact tcgggtatgt
    15181 acgactacga aggcgttgcc ctctttggag acaaactgat tgccaaacgc cattcaatga
    15241 gtatgggtga cgaaatttac gcaatagctt tggacggaca aaccacgcaa ctgacccaag
    15301 agaacaagca aatctatgac cagatcgaaa tgggtaaagt agaaggccgc tggatgaaaa
    15361 caactgacag caaagagatg ctgacatggg tcatctatcc gcctcaattc gatccgaata
    15421 agaagtaccc gacactgctc ttctgcgaag gtggtcctca gagtccggta agccagttct
    15481 ggagttatcg ttggaacatg cagattatgg ccgccaacgg ttatatcgtc gtagctccga
    15541 atcgtcgcgg acttccgggc ttcggattgg aatggaacga ggctatcagc ggtgattacg
    15601 gtggtcaatg tatgaaggat tatttcacgg ctatcgacga aatggccaaa gagccgtttg
    15661 tggatagtga tcgtctgggt tgtgtaggtg ccagcttcgg aggattttct gtgtattggt
    15721 tggccggaca tcacgacaag cgcttcaagg catttattgc ccacgacggt atcttcaata
    15781 tggaaatgca atatctggag acagaagaaa aatggtttgc caactgggat atgggcggcg
    15841 cttactggga aaaacagaac ccgacagccc aacgtacatt tgccaattct ccccatttgt
    15901 ttgtcgaaaa atgggatact ccaattctct gtatccacgg tgagaaagac taccgcatcc
    15961 ttgccaacca ggcaatggct gcattcgatg ctgccgtgat gcgtggtg
//
