LOCUS       gnlProkkaCNNODJGE_74    8525 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CNNODJGE_74.
ACCESSION   gnlProkkaCNNODJGE_74
VERSION     gnlProkkaCNNODJGE_74
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 00:10:27
            Original ID  :: gnl|Prokka|CNNODJGE_74
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8525
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..78
                     /locus_tag="ctg65_1"
                     /transl_table=11
                     /translation="MSYNQYTKIDKERKTQFIYKNILLL"
     protocluster    1..8525
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1281:8305]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1282..8305
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..8525
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8525
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             251..769
                     /locus_tag="ctg65_2"
                     /transl_table=11
                     /translation="MSEQQEYWFAARTKKDQEFSVRNALEKLGIEYFLPTQFVIRQLKY
                     RRRRVEVPVIKNLIFVRTTKDRAWSITKDDHVPLYYMKDLYTHTLLIVPNKQMEDFKFV
                     MDLAPENVTFDDLPLTIGTKVQVVKGEFCGIEGELSSLANRTYVVIRIHGVLSASVKVP
                     KSYLRILSA"
     CDS             789..1262
                     /locus_tag="ctg65_3"
                     /transl_table=11
                     /translation="MNQVQNLQHIARELLYLGMDGSPIYTDHFRQLNTEVFRLSEALFS
                     MKGTTSEEEAAICLSLLMGYNATIYNDGDKESKIQSILDRSFAVLDHLPASLLKCQLLT
                     YCYGEVFEEDLAQEAHQIMDSWKNRALSEEELEVMETLQTMEDNRYPCSEVED"
     CDS             1282..2169
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 271; E-value:
                     1.9e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_4"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.6e-14, bitscore:
                     41.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLYPITKGISKQLLPIFDKPMIYYPISVLMLAG
                     IRKILIISTPYDLPGFQRLLGDGSDFGVHFLYAEQPSPDGLAQAFIIGEEFIGDDSVCL
                     VLGDNIFYGQSFTRMLQEAVRTVESENKATIFGYWVKDPERYGVAEFDNDGNVLSIEEK
                     PDTPKSNYAVVGLYFYPNRVVKVAKNITPSFRGELEITTVNQHFLLDQKLKVQLLGRGF
                     AWLDTGTHDSLSEASTFIEVIEKRQGLKIACLEGIALRQGWISSEKMKVLAQPMLKNQY
                     GQYLLKVIDELSVK"
     CDS             2180..2734
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_5"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 4.9e-73,
                     bitscore: 234.0, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEILKTTIEGLIIIEPKLFWDGRGYFFESFNQKEFEEKVCKIVFV
                     QDNESKSHYGVIRGLHFQKPPFAQSKLVRVIKGAVLDVAVDIRKGSPTFGKYFSVELTE
                     DNHRQFFIPRGFAHGFSVLSEEVIFQYKCDNFYHPEAEGAIVWNDTELKIDWKIPIEKI
                     TLSEKDKAYPNFMDQDFHFNY"
     CDS             2741..4024
                     /locus_tag="ctg65_6"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGSSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             4038..4736
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_7"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.3e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             4756..6057
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_8"
                     /sec_met_domain="CTP_transf_like (E-value: 2.8e-13,
                     bitscore: 39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1e-122, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 5.1e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             6069..7205
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_9"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.7e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             7202..8305
                     /NRPS_PKS="Domain: Aminotran_5 (30-298). E-value: 6.2e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg65_10_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_10"
                     /sec_met_domain="Aminotran_5 (E-value: 8.4e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAVKFVK"
     aSDomain        7292..8095
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg65_10_Aminotran_5.1"
                     /evalue="6.20E-34"
                     /label="ctg65_10_Aminotran_5.1"
                     /locus_tag="ctg65_10"
                     /protein_end="298"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQS"
     CDS             8316..8525
                     /locus_tag="ctg65_11"
                     /transl_table=11
                     /translation="MEDLNRYNKEGSDLRKLQYRMLELLEVLDKICKKHNLPYWLEGGT
                     LLGAVRHGGFIPWDDDLDVQMLRSD"
ORIGIN
        1 tactcttata atcagtatac taaaatagat aaagaaagaa aaactcaatt tatttataaa
       61 aatattttgt tgttataaaa atgtgcctta cctttgtgtt tataaacgaa cgttttttga
      121 aacaatttca ttcgttttac cactaaaaat agtttcggaa attcttacgg tttgaatggg
      181 aaaagatgtc tcgtccaaac cgcgtagcgc acccgaaagt aacctctcga cttttaatat
      241 ccactaataa atgtctgaac aacaggagta ttggtttgcc gctcggacaa agaaggatca
      301 ggagttttct gttcgcaatg ctttagaaaa gcttggaata gaatactttc ttccaacaca
      361 atttgtcatc cgtcaactga aatatcgtcg tcgtagggta gaagttcctg ttatcaagaa
      421 tcttattttt gtccggacca cgaaagaccg tgcctggtct atcacgaagg atgatcatgt
      481 tcctctttat tatatgaagg atctctatac ccatactttg ttgatcgttc ccaacaaaca
      541 gatggaagat ttcaagtttg tgatggattt agctccggaa aatgtaactt ttgatgatct
      601 tccccttacc attggtacaa aagtgcaggt cgtcaaagga gaattttgtg gcattgaggg
      661 cgaattgtcc agccttgcca accgtactta cgtagtgatt cgtatccacg gagttctttc
      721 tgccagcgtc aaagtaccta aaagttacct tcgtattctt tcagcgtaat tcgtaatttc
      781 aaaattatat gaatcaagtc caaaatctgc aacacattgc ccgtgagttg ctttatttgg
      841 gtatggatgg ttctcccatc tataccgatc atttccgtca actgaacacc gaagtttttc
      901 gcttgtccga agcccttttc tctatgaaag gtaccacatc cgaggaagaa gcagcgattt
      961 gtctgtccct gttaatgggc tataatgcta ccatttacaa tgatggcgac aaagaatcta
     1021 agatacaaag cattttagat cgctcttttg ccgtattgga ccatcttcct gcttctctat
     1081 tgaaatgcca attgctgact tattgctatg gcgaggtatt cgaggaggat ttagcacaag
     1141 aagcacatca aataatggat agctggaaaa atagggcact ttcagaagaa gaattggaag
     1201 tgatggagac attgcagaca atggaagata atcggtatcc gtgtagtgag gtagaagatt
     1261 gataaaataa catataaaaa aatgaaaggt attgttttgg cgggtggttc aggaacacgt
     1321 ttatatccta ttactaaagg aataagcaag cagttgcttc ctatttttga taaaccgatg
     1381 atttattatc ctatttcagt tcttatgtta gcaggaattc ggaaaatatt aattatttct
     1441 actccgtatg atttgccagg atttcaacgt ttattaggtg acggctctga ctttggggtt
     1501 catttccttt atgctgagca accttctcct gatggcttgg cgcaggcttt tattattggt
     1561 gaagaattta taggagatga ctcagtatgt ttggttttag gagataatat tttttatggg
     1621 cagagtttta ctcgtatgtt acaagaggca gtccgtacag tagagtcaga aaataaagca
     1681 accattttcg gttattgggt gaaggatccc gaacgttacg gtgtagcaga gtttgacaat
     1741 gatggcaatg tacttagtat agaagaaaaa cctgatacac ctaaatctaa ttatgccgtt
     1801 gtaggacttt atttttatcc aaatagagtt gttaaagtgg caaaaaatat aactccttct
     1861 ttccgaggag aattagaaat aacaactgtt aatcaacatt ttcttttgga tcaaaaacta
     1921 aaggttcaat tattaggccg tggttttgct tggttagata cgggtacgca cgactcttta
     1981 tctgaagcaa gtacctttat tgaagtgatc gagaaacgtc aaggtttaaa aatcgcttgt
     2041 ttggaaggga ttgcactgag gcaaggatgg atttcttcgg agaagatgaa agtattagca
     2101 cagccaatgt tgaaaaatca atatggccaa tatttattga aagttattga tgaattatca
     2161 gtaaagtaaa tgtcttttta tggaaatatt gaaaacgaca atagaaggac ttattattat
     2221 tgagcctaaa cttttttggg acggtcgggg ctatttcttt gaatctttta atcaaaaaga
     2281 atttgaagag aaagtatgta agattgtgtt tgttcaagat aacgaatcca agtctcacta
     2341 tggcgttata cgcggtcttc atttccagaa acctcctttt gctcagagta aattagttag
     2401 agttattaaa ggggctgttc ttgatgttgc agttgatatt cgtaaaggtt caccgacatt
     2461 tgggaaatat ttttcagtag aactaacaga agataatcat cgtcagtttt ttattccaag
     2521 aggattcgct catggcttta gtgtattaag tgaagaggtc atttttcaat ataaatgtga
     2581 taatttttat catccggaag cggaaggggc gattgtttgg aatgatacag aattgaagat
     2641 tgattggaag ataccaattg aaaaaattac attgagcgaa aaggataaag catatcctaa
     2701 tttcatggat caagactttc attttaatta ctagaagata atgattcgtt cctttctttc
     2761 ccgttctccc ctttacgttt tggctctcta tgccagcgtt ttgatttttc tggtttatac
     2821 ttgtgcctat gcctaccgta agccatttac cgcagccatt tatgaaggtg agattctttg
     2881 gggattcgat gtcaaaatcc tgtatgtcct ttctgagatt atcggctacg ccctttccaa
     2941 gttcatcggt gttcgtattc tgccttcgat gaaagcgggt caccgcatct attatataat
     3001 agggctgctt actttttccg aagttgcttt gttgggtttt gcacttcttc cggttccttt
     3061 gaaggtgtgt tctatttttc tgagcggtct tcccctgggt atgatctggg gtgtcatttt
     3121 tagctatatc gaaggacgtc gtatcagtga aatattgaat gtcgggctga gcgttgcttt
     3181 gatagtctct tccggtttgg tgaaaacctt gggacaattc gtgatggata atttgcatgt
     3241 gtcggaatat tggatgcctt ttaccaccgg tttgttggta taccctgtta tgttgctttg
     3301 cagctggctt ctcaatcaga ttccggctcc caatgagcaa gatatcatac agcgtaccaa
     3361 acgtgctccg atggatggta aagacaggcg taaatttttg aggcaattct tttggggaat
     3421 ctgcatgctg gttgtttttt acggtgccct gaccgtgttc cgtgagcttc gtgactcttt
     3481 cgctgccgat atttggaagg agctccatat tgagggtgca atgatcttta ctcagacaga
     3541 ggttcccatt gccgtttttg tccttgtact gatgttcctg attgtgtttg tccgtaataa
     3601 ccgtttggct cttaatatca tttattgcat cgccgtcaca ggcagttcct taatggtttt
     3661 ttccacattg ctttatgtgt acggttttct ttctcctatt tggtggatga ttctttccgg
     3721 tcttggtctg tatatggggt atattccttt cacttacctg atagaacgtc tgattgcttc
     3781 ccttagggtg gttagtacgg ctgtttttat tatttatttg gccgattctt tcggctatct
     3841 gggcactacg ggtgtgttta tggtcaagaa cttcgtttct gctgacattt cctggactgt
     3901 catgctgatg cgtactgccc ttttttcagg atttgtttct gtcctgtcga tttttgcgat
     3961 ttactgttat ttcaagcaac aattgaattc acttatatta attccctctg aaattcatga
     4021 ttaaaacagc aatgatcatg gctgccggtc ttggtacccg cttcgggcat tataccgagc
     4081 ttgtgcccaa aggttttgtg gaggttggtg gaaaacctat gattatccgc tctatcgaaa
     4141 cccttctttc ctgcggtatc gaacgtatca tcctcggtac gggttataaa aaagaggctt
     4201 atgaagccct tcaggcggat ttcccccaga tagagacctg tttcagtccc cgttatgccg
     4261 atactaacag tatgtacact ctgtacaata cgcgtgacgt gataggcgat gacagtttcc
     4321 tgctgcttga atcggacctt gtttttgaac gcaaggccat cctctcgctg ctggatgacg
     4381 aattcccgga tgtgatgctt gtctcttctc tgaccaagtt ccaggatcag tattatgtgg
     4441 aatatgaccg caatcacatc cttacttcct gttcggtaga caaggacgcc cttgaggcaa
     4501 aaggcgagct ggtcggtatc cataaacttt ccaatacttt ctaccgccgg atgtgcgccg
     4561 attatgcgac catcctggag tcccagccta aactgggtta cgagtacgaa ctgctccgca
     4621 tgtcccgttc cgtttcccct gtccgtgtgc tcagggtgga gggtcttaaa tggtatgaaa
     4681 tcgatgatga agccgacctt tcgtatgctg aggagcacat catccgctat tgttaaaaac
     4741 aaatcttttc catatatgaa caagaaaatc tatgtcggta tgaccgcgga tatcatgcat
     4801 ccggggttga tccatattat tcatgaagct actaaatacg gtgatgtcat cgtcggtctg
     4861 ctgacggaca aggccatcgc cgaacacaaa cgcctccctt accttaccta tgatcagcgt
     4921 aaggaggttg ttgagaatat caaaggggtt tgcgaagttg ttccccagga ggattggagc
     4981 tatgttccga atctggaaaa actcaagcct gactatatca tccacggcga cgactggaaa
     5041 acgggcccgt tgcgcgaggt gcgcgaacag gtttttgagg tgatgaacgc ccaggggggc
     5101 aaggtaatcg agatccctta tacccggggc atcaactcct cctcgctcga caaggatatc
     5161 aaggcgatcg ggactacccc tgacgtacgt cttaagtccc tccgccgcct gatccaggcc
     5221 aagcctgtgg tccgtatcct ggaggctcac gacggtcttt gcggtctgat tattgagaat
     5281 cttgaagtcc agaagggtga taagcgcgag gtctttgacg gcatgtggtc cagcagcctg
     5341 accgactcca cgagtaaggg taaaccggat attgaagcgg tcgaccttac cacccgttta
     5401 caggacctga acaatatcct tgaatgcacc accaagccta ttatttttga tggagacacg
     5461 ggtggcaaga tcgaacactt tgtctttact gtgcgcactt tggaacgtca cggcatttct
     5521 gcggtaatca ttgaagataa agttggtctg aagaagaatt ccctttttgg tactgacgct
     5581 atccagactc aggatagtat cgagggtttc tgcgataaga tcagagcagg gaagaatgcc
     5641 caggtcaccg gtgactttat gatcattgcg cgtatcgaaa gccttattgc cggcaaaccc
     5701 atgagtgacg ccctcgaacg tgcttatgcc tatgtacagg cgggtgcgga cggcatcatg
     5761 atccacagca aggataagtc gggggaggat atccgtgagt tctgccggac tttccgcaaa
     5821 gaatacgccc atgttcccat tgtcgttgtt ccgacgactt atgaccatgt gcacgaatcc
     5881 gaacttcacg aatggggtgc caacgtagtc atttacgcca accaccttct ccgtgccgct
     5941 tatccggcca tgatgaacgt ggccaggacc atccttgaaa acgagcgcgc cgaggaggtc
     6001 cgtccgcttt gtatgcctat caaggaaatt ctggaattga ttccgggcac taaataaatc
     6061 agacggttat ggtaagtgta gaaaagatat acgatacgtt ccttcatcac ggtgttgact
     6121 tctttacggg tgttcccgat tcccttttga agaatatttg cgcctatatc acggatcatg
     6181 ctccgcgtgg taagcatatc atcgccgcca atgaaggttc cgcggtgggc attgcctgcg
     6241 gttattatat ggcttctggc aacgttcctt tggtttatat gcagaactcc ggtctgggaa
     6301 atacggtgaa tcccctcttg tcccttgcgg acgagaaagt gtacagcctt cctcttcttt
     6361 tgctggtcgg ttggcgcggt gagcccggca cgaaagacga accccagcat aagaagcagg
     6421 gcgaggttac ccttgatctt ctgaaagcca tgaaaattcc ttttataatt ctggatacgg
     6481 atgaagacga ggccctggcg cagatccatg acgcggttgt ctcggcgaag agccggtcga
     6541 ttccccatgc gattgtcatc cgtaaagata cgtttggaaa atataaattg cgtcaggaag
     6601 ccttgaatga ctatcctctg tcccgcgagg aggcgctaat gcaggttgtc gaccacctcg
     6661 gggacaatga cattgtggtt tccaccacgg gcaagctctc ccgtgagctt ttcgagtacc
     6721 gtgaatcgaa agggcagggg cacgcaaggg atttcctaac tgtgggttcc atgggtcaca
     6781 gttcttccat tgccctgggg attgcccttg agaagcctga ccgccgtgtc tactgtcttg
     6841 acggtgacgg tgcctttatc atgcacatgg gtgctgtcag caatatcggc gatctttctc
     6901 ccaagaatta caggcacgtc cttttcaata acggtgccca tgaatctgtc ggcggtcaac
     6961 ccacgctcgg tttccgtctg gatatcgcct cgatagcgaa aggttgcggt tatgcgcatg
     7021 tactgactgc ctccgacaag gaagggcttt cgtgtgcgct tgagaagctg tccggcctgt
     7081 ccggcccggt tcttcttgaa attaaggtcc ggatcgattc acgtgatgat ctgggtcgcc
     7141 ctacgactac tccggtagag aataaagagc attttatggc atttttaaaa gatacgcatt
     7201 catgaatatc gaaagaaaga tccttttgaa tccgggtccc gccaccacga cggatacggt
     7261 gaagctggcg caggttgttc ccgatatctg tccgcgtgag aaagagtttg cgggtatgat
     7321 gaaacagtta cgtgacgacc tggtccgcgt tgcgcatgga gacctctcca aacatacggc
     7381 cgtcctgttt tgcggctcgg ggacgatcaa tatcgatatc tgcctgaact ctcttcttcc
     7441 tgcggataag aaagttctgg ttgtcaataa cggtgcctac agcacccgtg cggtggaagt
     7501 ctgcgaatat tacggtcttc cccatatcga tttgaagttt tccgtttacg aacttcccga
     7561 cctgtcggta atcgaaaaga cgctttccga caatccggac atcgctttgg tctataccac
     7621 gcaccatgaa acgggtacgg gtatcttgaa ccccatccgt gagatcggaa aaatagccca
     7681 ttcgcacggt gccgtttttg ttgtcgacac cacttcctcc ctgggtatga ttccttttga
     7741 tatcgggaag gataatgttg acttttgtat ggcttcggct cagaaaggcc ttcaggccat
     7801 gacggggctt tcctttatca taggtgatga atccctgata cgtgcttcaa gggattatcc
     7861 gaaacgttcc tactattgta acctctattt acaatacgat tactttgaga agacgggcga
     7921 gatgcatttt actcctcctg ttcaaaccgt ttacgctgcc cgtcaggctc ttgatgaata
     7981 ttttgcagta ggtgaagagg ctaaattcgc ccgtcacaag agggtctttg aagccatcca
     8041 taaaggtttg caagagcttg gtcttcagta tgcgatcaaa cgtgaatggc agtcgggtct
     8101 tgttgtttct gtattgtatc ctgatgatcc cctctgggat tttgataagg ttcatgatta
     8161 ctgctatgaa cgtggcttta cgatctaccc gggtaagatt tccacaacga atacattccg
     8221 gctttgtgcg ttgggagaga ttgatgtgga ggatattgag aggttctttg aggtgatgag
     8281 agaagctgtg aaatttgtta aataaatttg tattaatgga agacttaaat agatataata
     8341 aagagggttc agatttaaga aagcttcaat accgtatgct ggaattattg gaagttttag
     8401 ataagatatg taaaaagcat aaccttccat attggctaga gggagggacc ttattaggtg
     8461 cagtaaggca tggaggattt attccttggg acgatgattt agatgttcaa atgcttcgtt
     8521 ctgat
//
