LOCUS       c00050_gnlPro..        24639 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LBJPHBFC_58.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 21:16:51
            Original ID  :: gnl|Prokka|LBJPHBFC_58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 217396
            Orig. end    :: 242035
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24639
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[227396:232035]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14639
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             238..1752
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 267.1; E-value:
                     7.1e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_172"
                     /sec_met_domain="AMP-binding (E-value: 3e-81, bitscore:
                     267.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSPQKDIINDILSAMQCYPENEAFIIDDKHYTYAQLGEITASI
                     THSLSEIKDERIGIVAENRIETYAAILAVLAGGKTYVILHPAYPKERNLKIAALAGLRT
                     LLCTSDTDRSAFGTGHFRIIDTDRLPGKALSEQQSHSSDEERNAYIIFTSGSTGEPKGV
                     PITRANLNAFYRAYSSLDWNLDEHDRMLQMFELTFDVSVVSLLYPLTLGAAVYTVGHQD
                     VKHFKVFELLEKYELTFATVTPSLLQLLSPYFDEINLPSLKYLGVSAEASQTELLERFR
                     KSAPNATFINLYGPTEATIYCTCYRIPASDKCKHYNGMVAIGKPFPGIRAIIADEEGNE
                     LPQGETGELWVSGRQVMKGYLDDPEKSTLVLIHRPDGQIYYRTGDLCILDSDGDIIYCG
                     RKDYQVKIQGFRIELSEIEYTAQSFFKTPCSVAAVPLLCDGICNELHLAVETTECTQSA
                     LIEYLKEKLPKYMLPKQIHCISQFPVTNSNKTDRKKIAELIKEKKL"
     CDS             1767..2009
                     /locus_tag="ctg50_173"
                     /transl_table=11
                     /translation="MNREEVLKQLQSIFRDILKKDNVCIDESSTSKDVDGWDSLTHMQI
                     IAQIEKHFGVRFYFREVIKFKNVGDLCSALLTKME"
     CDS             2013..3395
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MBOAT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_174"
                     /sec_met_domain="MBOAT (E-value: 1e-20, bitscore: 68.3,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFLSFSFLALFTLCFFLYYAVKGRSRNLILLVTSCIFIGWYYLP
                     FLLTAVVVALFTFFWAQWMESRAKAGKKTKPVYIAGIIALIGGWLLLHGTVIDDIIFPL
                     GMSFYTFQAISYLTDVYWQEQRSERNWVDFLIYMLFFMKFLSGPIERGGDLLPQLKDPR
                     PFIYSNAVTGLKYILLGLIKKLLIANQISPQTDVMFHSIHDLSGVQLLMTCLLYPIELY
                     ADFSGYTDIAIGGAYMFGIKLSPNFNRPFAARSTADFWRRWHMSLSFWVRDYLYVPLTA
                     GTRNWGQWGIYFSLLITFLALGLWHGAGLTFAIYGLIQGVLICWEMKTAAFRNNLPQYI
                     GKYAADSLLIVRTYLLFALSLIFFRVQSLNDAWYFLRNISFEVHSSWKEMNIGIRDHNC
                     IVAGSALLLVLIYEYYASKYNLMETLERQPAWLRWSVYYLLVFALLMLGKFDTETFIYL
                     QF"
     CDS             3414..4454
                     /locus_tag="ctg50_175"
                     /transl_table=11
                     /translation="MLHHSSRISPKTRFCLKLLLLILPLIPIVVVYFMFDPYRVLHPYK
                     RFDDSPMLLNEAHVGWQNYLQNRDSIAYNSFILGNSCTMAFLTGEWEKYLDKNDHAVRF
                     YDNGESLGGVRQKLQLLDSVGAPLKNILIVLDKKSLDKNAPLSGNNHLFSAEAAGISQL
                     GFQLRFLQEFLYPDRMIPYIDYLIRHKYAPYMKGVINPGDPVREPYTNNFINPREKEIA
                     QDGEIYWSRHEKEFKKRTNAGMEELPVIFASQIQVLRSIKKICDKHHTNLKFIIGPDYY
                     QKKTSREDIKILKAILGDSAVWDFTGINEYTADIHHYYEPGHYRPLLGARLLKAIYQDQ
                     DTCHRQ"
     CDS             4559..4951
                     /locus_tag="ctg50_176"
                     /transl_table=11
                     /translation="MKKILLLLSVCISFSSCCTLFSSSKQDITFTGMNGTKIYEASTKQ
                     KIAEIKEDNSVTVQIKKKREDKQLVAKKEGYQTTPFVLESTFNNACLWNILFWPGFLVD
                     LGTQKMNKWDNTIINIEMEKENTENK"
     CDS             complement(5144..5776)
                     /locus_tag="ctg50_177"
                     /transl_table=11
                     /translation="MMLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGV
                     DYVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKAL
                     GKPVGKQDAIEMLRSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVD
                     HYQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPIQKLYRELKQL"
     CDS             complement(5757..6278)
                     /locus_tag="ctg50_178"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALAFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKHGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(6299..7090)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_179"
                     /sec_met_domain="F420_oxidored (E-value: 4.2e-13, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVSHYGVFYPMQTFSKQREVDFKEIPFFIEASSAEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(7087..7419)
                     /locus_tag="ctg50_180"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFMKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(7422..7919)
                     /locus_tag="ctg50_181"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLG
                     ELSHCKEQASAFIADAALAIVVTTDPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(8124..8666)
                     /locus_tag="ctg50_182"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMITHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             8784..9767
                     /locus_tag="ctg50_183"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLTAEADKERIFGEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENTEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALRDAHQNGFRHMEF
                     MDVGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_184"
                     /sec_met_domain="Glyoxalase_4 (E-value: 5.5e-23, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10531..12084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_185"
                     /sec_met_domain="CT_Btheta (E-value: 5.3e-290, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12105..13019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_186"
                     /sec_met_domain="OAD_gamma (E-value: 3.3e-15, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTVDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             13045..13476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_187"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2e-21, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             13479..14639
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_188"
                     /sec_met_domain="OAD_beta (E-value: 1e-152, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14788..16119
                     /locus_tag="ctg50_189"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALRELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             16132..17424
                     /locus_tag="ctg50_190"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVMLRAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPKNQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIGDTKATEHYLQAFLRTKSKQNAVLQQPDDD
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             17840..19690
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_191"
                     /sec_met_domain="Alpha-amylase (E-value: 1.4e-62, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWADDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             19848..20288
                     /locus_tag="ctg50_192"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGAEMEASRITECIEDLKRLHEVLNEI"
     CDS             20301..21368
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_193"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 5.7e-11,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLAHLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATQARYNALLQQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             21373..22968
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_194"
                     /sec_met_domain="MFS_1 (E-value: 2.9e-13, bitscore: 43.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFIICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIALFIHRQRTQGKPFVSLKPLFLHKSIIGYSF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFSEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(23063..24067)
                     /locus_tag="ctg50_195"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKNPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFDVLDGV
                     MKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAE"
ORIGIN
        1 gtatcaataa agtatcgtgt tgtctatccc attcaaagtc gtcggctatg aagccaacgc
       61 tatttcccct tccgaaaaag ggaaagcgag accgggcatg tgcgtaccac acaattaaca
      121 ttctttaatc gattgtgcgt agggagatca gaccatttca ctgtcatctt aataaacgat
      181 ctcaagaaga tatataaaga acccctaaac ccaaaacatg aataaaaact aatggatatg
      241 acaacatctc cccagaagga tattatcaat gatattcttt ccgccatgca atgttatccc
      301 gaaaatgaag cattcattat tgacgataaa cattatactt acgcccaact cggtgaaata
      361 acagcttcta tcacccattc gctatcagaa ataaaagatg aaagaatcgg aatcgtagcg
      421 gaaaaccgga ttgaaaccta tgcggctatt ctggcagtac tggccggtgg aaagacctat
      481 gttatcctgc atcctgccta cccgaaagag cgtaatctca aaatagccgc tctggccgga
      541 ctgcgtactt tgctctgtac aagtgacact gaccggtcag cattcggcac cggacacttc
      601 agaatcatcg atacggaccg gctaccggga aaagcactgt cagaacagca gtcccattca
      661 tcggacgaag aaaggaacgc ttatatcatt tttacatcgg gaagcacagg cgagcccaaa
      721 ggagtgccca tcacacgggc taacttgaac gccttttacc gggcatacag ttcgctcgac
      781 tggaatctgg atgaacatga tcgcatgttg caaatgttcg aacttacatt cgatgtatcc
      841 gtcgtatcct tactgtatcc tcttacttta ggtgctgccg tttatacggt aggccatcag
      901 gatgtaaagc acttcaaggt gtttgaactt ctggagaagt atgaactgac ctttgccact
      961 gtcactccct cactgctaca actcctttca ccctacttcg acgaaatcaa tctgccctct
     1021 ctgaaatatc tgggagtatc ggcagaagca tcgcaaaccg agctgttgga gcgattcaga
     1081 aaatcggcac ccaacgcaac gttcatcaac ctatacggac cgaccgaggc tacgatttac
     1141 tgcacctgtt accgtattcc ggcttcggac aaatgcaagc attacaacgg aatggtggct
     1201 atcggaaaac catttcccgg catccgcgcc atcattgccg acgaagaagg aaacgagcta
     1261 cctcaaggag agacgggaga actttgggta tccggccggc aggtaatgaa aggttatctg
     1321 gacgacccgg aaaaatcgac attggttctg atacaccgtc ccgacggaca aatctattac
     1381 cggaccggag acttgtgtat tctggatagc gacggggata ttatttattg cggacgtaaa
     1441 gactatcagg tgaaaataca gggtttcagg atagaactga gtgaaataga atatactgcg
     1501 cagtcgtttt tcaagactcc ctgcagcgtg gctgccgttc cgttgctctg cgacggaatc
     1561 tgtaacgaat tacatctggc cgtcgagaca actgaatgta cccaaagcgc attgatagaa
     1621 tatctgaaag aaaagctgcc caaatacatg ctgccgaagc agattcattg tatttcccaa
     1681 tttccggtga ccaatagtaa taaaacagac cgtaaaaaga ttgccgaact gataaaagag
     1741 aagaaactct aaaaacaata ataaatatga atcgagaaga agtattaaaa caactacaaa
     1801 gcattttccg tgatatctta aaaaaggaca acgtatgtat cgacgaatca tctacctcaa
     1861 aagatgtaga tggctgggac tcgctgaccc acatgcaaat tatagctcaa atcgagaaac
     1921 atttcggagt acgtttctat ttcagggagg tcattaaatt caagaatgtc ggcgatttgt
     1981 gcagtgcctt attaaccaaa atggaataaa cgatgcagtt cctctctttt agtttcctgg
     2041 ccctgtttac cctctgtttc ttcctctact atgcagtcaa aggccgttcc cgcaacctta
     2101 tactactggt aaccagttgt attttcatcg gatggtacta tctgcctttc ctgttgacgg
     2161 cagtagtggt agcactgttc accttctttt gggcacaatg gatggaaagc agggcaaaag
     2221 ccggaaaaaa gaccaaaccc gtctatatcg caggaatcat agccctgatc ggcggatggc
     2281 tccttcttca tggcacggtc atagatgata tcatctttcc acttgggatg tcattttaca
     2341 catttcaagc catcagttat ctgacagacg tgtactggca agagcaacgc agcgaaagaa
     2401 actgggtgga tttcctgatc tatatgcttt tcttcatgaa gtttctctcc ggccctatcg
     2461 aacggggtgg agacctgttg ccacaattga aagatccccg cccgttcatc tactcaaacg
     2521 cggtgaccgg actgaaatat attttactcg gactgatcaa gaaactgctg atagccaatc
     2581 agatctcccc acaaacagat gtcatgtttc attcgatcca tgacctctcg ggtgtacaac
     2641 tgctaatgac ttgcctactc taccctatcg aactgtatgc cgatttttcg ggttatacgg
     2701 atattgctat cggaggggcc tatatgttcg gcatcaagtt gtcgcccaac ttcaaccgcc
     2761 cgtttgcagc acgctcgact gccgacttct ggcgccgttg gcacatgtca ctctccttct
     2821 gggtacgcga ttatctctat gtaccgctaa ccgccggtac ccgtaactgg ggacagtggg
     2881 gaatctactt cagcctcctc atcacctttc tcgcattggg tttgtggcat ggggccggat
     2941 tgactttcgc catatacggc ctgattcagg gtgtccttat ctgctgggaa atgaaaacag
     3001 ctgctttccg caataatctg ccccaatata taggaaaata tgcggccgac agcttgctga
     3061 ttgtccggac ttatctattg ttcgcactct cgcttatatt ctttcgtgta caatcgctga
     3121 acgatgcctg gtatttctta cggaacatct cgttcgaggt acattcttcc tggaaagaaa
     3181 tgaacatcgg catacgcgat cataattgca tcgtagcagg ttcggcccta ttactggtat
     3241 tgatctacga atattatgca tctaagtaca acctgatgga aacacttgaa cgccaacccg
     3301 catggttacg gtggagtgtc tactatctgt tggtattcgc tctgctgatg ttaggcaaat
     3361 ttgacacgga aactttcatc tatttacaat tttaaccgaa accctttacg cgcatgctac
     3421 atcattcatc gagaatctcc cccaagacac gtttttgcct gaagttgctt ttactgatcc
     3481 tgccgctgat cccgatagtg gttgtctatt ttatgtttga tccttatagg gtattacacc
     3541 cctacaaacg attcgacgac tctcccatgc tactcaacga agcccatgtg ggatggcaga
     3601 attatctgca gaatcgcgat tcgatagcct ataactcctt tatactcggc aactcctgta
     3661 ccatggcatt cctgacagga gaatgggaaa agtacctgga taagaacgac catgccgtac
     3721 gcttctatga caacggagaa agcctgggcg gcgtccgtca aaagcttcag ctgctcgact
     3781 ctgtaggtgc acccctgaaa aatatactga tcgttctgga taaaaaatca ctggacaaaa
     3841 acgctccttt atcgggcaac aatcatctgt tttcggccga agcagccggc atcagccaat
     3901 tgggattcca gttgagattc ctgcaggagt tcctttatcc ggacagaatg attccttaca
     3961 tagattatct gatccgacat aagtatgctc cttatatgaa aggggttata aatccgggag
     4021 atcccgtcag ggagccttac acgaacaatt ttatcaatcc cagagaaaaa gagatcgcgc
     4081 aagatggcga aatatactgg agccgtcatg aaaaagaatt caagaagcga acgaatgcgg
     4141 gtatggaaga acttcctgtt atatttgcca gccagattca ggtacttcgc tccatcaaaa
     4201 aaatctgcga taagcaccac acgaacctga agttcatcat cggtccggat tactatcaga
     4261 aaaagaccag ccgggaagac ataaaaatat tgaaggctat actgggtgat tccgctgtct
     4321 gggatttcac gggaatcaac gaatacacag ccgacataca tcattattac gaacccggtc
     4381 attatcgtcc gctgctggga gcacgcttac tgaaagccat ttatcaggat caagacacct
     4441 gccacaggca ataaaagttc ctcccataac agtagcacac acagaagaag agcatcctcg
     4501 atccgaaaga aataattaga tcaaagaaaa caattatatc acattaaaaa cttagattat
     4561 gaaaaagatt ttattattgc tatccgtctg tatttcattt tcatcatgct gtacattatt
     4621 cagcagttcc aaacaagata tcacctttac gggaatgaat ggaactaaaa tctacgaagc
     4681 atcgaccaaa cagaaaatag cggaaatcaa agaagacaat agtgtcactg tacaaatcaa
     4741 aaagaaaagg gaagacaaac aactagtagc caaaaaggaa ggataccaaa cgactccctt
     4801 tgtcctggaa tctacattta acaatgcctg cctgtggaac attctatttt ggccgggctt
     4861 tctggtagat ttgggtacgc aaaagatgaa taaatgggat aacacaatta tcaatatcga
     4921 aatggagaaa gaaaatacag aaaacaaatg atcaaactat aatttcgcat ggcactcttc
     4981 tccttccacg gagggagccg ccatacggaa tcatgcgacc tacaaggaag gcatacttca
     5041 ccacaaggca acacagagtt ttttataaaa gttctttaga gaataaatct actctgtgag
     5101 actctgtgct actccgttgt atatacgagt ttcggcacac tctctatagt tgtttcaatt
     5161 ccctgtataa tttctgaatg ggaagtccca ttacattgaa gtagctgccg gatatggact
     5221 ctactccgac aaaaccgatc cactcctgca caccatacga accggctttg tccatgggct
     5281 gatagtgatc gacataataa gcgatttcat cttcatcaag aatcgcaaaa cggacatccg
     5341 tcacggcagc gaaacatttt tgccattctc gggtagtgag acacacaccg gtaatcactt
     5401 ggtgcgattt accggagagg ctccgcaaca tctctatggc atcctgcttt ccgacaggtt
     5461 tgccgagcgc tttgccttca tgccagacaa tggtatcggc tgtgatcaaa agctcttccg
     5521 gtccgatcat cgactgatag gcggctgcct tctcacgggc tatgaaaaga ggaatctctt
     5581 caccttgcaa cgtatcggga taagattcgt ccacatccgg caaagttttt actacataat
     5641 cgacacccaa gcccgtcatc agttctttgc gacgcggaga attagaggcc aatacgattt
     5701 tataacgatc taagttagca agcatactga taaataaata aggtatatac tggaaatcac
     5761 catccgaaag catcatcgga caaccattgg ccttgtgctt taagcacctg ctccaccaca
     5821 tcgcgtccac agccgtatcc tccatcggca tacgaaatgt aacgggcaat cgctttcacc
     5881 tcgggaaccg catctttggg acagcagggc aatccgcact cacgcatcac ttccatatcg
     5941 ggaacgtcat cgcccatgta gagtatctcc tcgtccgtaa gtccgtgttt gtcacggaaa
     6001 ccacgataat cgtgtatctt caccgcagag ccgaagtaca gatcggatac ccccaaccct
     6061 ataaaacgtt tccgcacgac atcgctccgc ccacctgtaa taatagcgat acgaagccct
     6121 ttttttacgg ccaattggat ggcataaccg tctttaacat ttaccgtacg catcggttca
     6181 cccgacggat gcaaagggat gacattggcg ctcagcactc cgtctacatc aaaagcaagt
     6241 gcttttatcc gggtaaggtc gtaattgatt gtgctcattt ttatttaatg tttcgggatt
     6301 attgtctttc gtgaatactt cggctaagca actcgtataa ccgctgcatg gcaggatcat
     6361 cggcaagcat ccgcaagtga ttgccgatca cattctcgtc ataacggatg gccggcccgg
     6421 tctgggccgt cttaggttcc agttcgtgca ccttacgggc ggtttcatca atcaacggca
     6481 acatcacgtc aaacggcaga ttgtatttct taagcaactc ggcagcaagg gcatacatgt
     6541 gattggtgaa gttacatgta aacacggcag ccagatggag acttttacgc tgctccgagt
     6601 cggcatcgta cacacggttg gacagtgtag aggcaatggc tttcagaaac gcggcatctt
     6661 ctgccgaaga agcctctatg aagaaaggaa tctccttaaa atctacctcc cgctgcttgc
     6721 tgaaagtctg catgggatag aacacaccgt aatgcgagac atgtccttcc cagacattca
     6781 tcgggatgct acctgccgta tgcaccatca atgcctcttc ccgcttacct tcgacaatgc
     6841 cctgaagaag ttcggcaaag gcggaatctt tcagtgaaac aatatacagc ttcgcatacg
     6901 ggttcacctc tgcgaggtct gtcgtatatt cggcttccac tttctgtgcc agctcgcggg
     6961 ccgactcttc cgtacggcta tacacctgta cgatacgaaa acctttccga tataaggctt
     7021 ttgccagatt agtggcaaga tttccggcac cgataaatac gatcggcgta tcttctatac
     7081 ttcttttcat cgtgttgaaa tcaaatacaa tatacctccg attatcaata aagccaaagg
     7141 cagcagataa ccggacatcg aaccaagcaa cgaaacaatc aggccgatgt tcagcaccaa
     7201 ccacaatccg agcaatacca agccgacgga tttatcccgc ttcataaaca ggaaaatcac
     7261 cgcagtgtaa agcaaaagat tatccttatt catcacccag ggtatcccca aagtggaaaa
     7321 gtgtatcagt ttgtcgatca gatagagcac ccccatcaca ataagggtga ctgctgtggc
     7381 tttgtaggta tctttattgt ttgcttttac cgcactcacc gttacttacc tccgaactta
     7441 ttaatatgga ttttttccca ttgcaaatgg tcttcattaa agggtttacg ttccatccct
     7501 ttatgcccga tcgctatgac ggacaacacc tgcaactgca aaggaatgtc gagcacaccg
     7561 cgcacaaatt catcggaagg catcccggtg gcagtatatc gctcacgcac ctgcacccag
     7621 caacttccca atcccaagtc ttcggcctga agctgaatca taatagaggc aatggaagcg
     7681 tcctcaatcc atacatcgct cgccaaggga tcggtagtaa cgacaatggc caatgccgcg
     7741 tcggcaataa aggccgaagc ctgctctttg caatgtgaaa gttcaccgag caacttttta
     7801 tcatcgactg cgataaactg ccagctgtta ctgcgctttg aagtaggagc catcagggcc
     7861 gctttcagca aagcgactac atcttcctga gaaagttctt ctccggtaaa tttccgcatg
     7921 ctgcggcgat tttttattag ttcactgaaa ttttccatgt atctatactt tgcattattt
     7981 gaatataccg ccagtcacca tagaatgcac aaacacacgc gaaccgaggt accacccggc
     8041 atgcccgtct atataaggta gccctgcagg actttgcatg aatcggcgcg ctccgtggcg
     8101 attcgggcgc aaagataggc aatttattcc actctcgtca actcgccggt cagtgaatcg
     8161 atgataaaac catgcacccg gacatctttc ggaataagcg gatggttctc tatggaacga
     8221 accgtgcccc tgacggactt caccggatcg tcgaatccgc ccagccacga attaaaatcg
     8281 accccgcagt agcgtatcat gtcgattgtt tcggacttga ttccccgctt tttcatgtga
     8341 gttatcattt cgtcgctgtt catgtggcaa gcaccgcaat cggaatgggc aatgaccatc
     8401 acttcttcta ctcccaactc gatgatggcc accagcagac tacggatgac actgccgaaa
     8461 ggatgggaaa tgacggcacc ggcattcttt ataatcttta cgtctccgtt gtgaatcccc
     8521 aaagcggcgg gcaacagttc tgtcaggcgg gtatccatac aggaaaggat ggcgattttc
     8581 ttatcaggat acttgttagt gatatacttt tcgtatcccc tgttctcaac gaactttttg
     8641 ttgaattcaa gaatttcttc taacataatc aaaaacggat tttattgtag tatctccaca
     8701 aagatagtca caaaacgaca gctcaacaaa ataagccctg caaatgttgt aaagagaaat
     8761 aaaaaatgta aatttgtccc gatatgccat taaaactgac tacatattac caaggaagtg
     8821 agattccgga ttttcccgga accaatacgt ttcattcgaa agagctattt cagatctacg
     8881 aagaaactcc gggctacacc ccgcttctga ttatggcttc ggaagacgga aaacctgttg
     8941 cgcgactgct tgctgccatc cgcaaaagca tccgcatgtt tcctcccgct ttcatcaaac
     9001 gctgcgaaat ctatggcacg ggcgaatatc tgacagcgga agccgacaag gaaaggatat
     9061 tcggcgaaat gctggagcac ctcaccacgg aggctttgcg gaactcgttt ctgatagaat
     9121 tccgcaatct ggagaacgcc atgttcggct acaaatattt ccggtccaac agatacttcc
     9181 ctgtcaactg gctgcgggta cgaaactcgc ttcacggcat cgaaaacacc gaacagcgtt
     9241 tcagcccctc ccgtatccgc cagatcaaaa aaggcctgaa aaatggagca aaagtagacg
     9301 aggcacgtac ggtagaagag atacgcgaat tttcgaatat gctgaggcat ctctattcgt
     9361 cccgcatccg taaacatttt cccaacatca tctttttcca gcacatggac acccggctga
     9421 ttcacagccg gcaggcaaag attttcatcg tccgctacaa agacaaaatt atcggaggct
     9481 ctgcctgtat ctattcggga aacgatgcct atctctggtt ttcgggaggt atgcggaaga
     9541 cctatgcctt gcaatacccg ggtatactgg ctgtatggaa agccctccgg gatgcccatc
     9601 aaaacggatt ccgccacatg gagttcatgg acgtcggact cccatttaag aagcacggtt
     9661 atcgtgactt cgtgctccgc ttcggtggca agcaaagcag cacccggcga tggttccgtt
     9721 tccgctggca atggctgaac gacctgctga tcaaaatata cgtctgaaca tccgcctgtc
     9781 tcagggatca gcgccaaccc tctccgcctt ttaaaccaac accccttagg ttttaaacca
     9841 acgatgcctg ccttttaaac ccatgcacct taggttttaa acctattttc accataatta
     9901 attgcagaaa aatttcttta ttaaacaaga attgattttc tttgtgctgt tttataccat
     9961 tccgaaaaga cgattaatac caaaatttaa aaatatagtt atgaagattt cacacattga
    10021 acatttgggc attgccgtaa aaagtatcga agaagccctt ccgtattatg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaactgt agaagatcaa aaagtaagaa cagccttcct
    10141 gaaagtaggt gataccaaaa tcgaattact ggaacccaca tgtccggaaa gtaccatcgc
    10201 gaaattcatc gaaaacaaag gtgcaggtgt tcatcacgtg gcattcgcca ttgaagacgg
    10261 cgtagccaat gccctagccg aagccgaaag caaagagatc cgcctgatcg acaaagctcc
    10321 gcgcaaaggt gccgaaggcc tgaacattgc tttccttcac ccgaaatcaa ctctgggcgt
    10381 actgacagaa ctctgcgaac actaaaaaga tgtacgattc ggacgatccg cgccacggac
    10441 aaacggaatt tttctttgca ttaaattccc catccgggtt gtcaatcgtc cggttgtaaa
    10501 tattataacc ctttaaatta agaaaaactc atgagtaacc agcttgaaaa agtaaaagag
    10561 cttattgaac ttcgtgctca ggctcgttta ggtggtggcg aaaaggctat tgaaaaacaa
    10621 cacgccaaag gcaaatatac agcccgcgag cgtattgcac agttgcttga cgaaggtagt
    10681 ttcgaagaac tggatatgtt tgttcaacac agatgtacca atttcggaca agagaaaaaa
    10741 catttcctcg gcgacggtgt ggtaaccggt tatggaacga tagaaggtag attagtatat
    10801 gttttcgcac aagatttcac agtattcggt ggttcactgt cggaaaccat ggcacaaaag
    10861 atctgtaaag taatggatat ggccatgaag atgggtgccc ctgtcatcgg tatcaacgac
    10921 tcgggtggcg cacgtattca ggaaggcatc aacgccctgt ccggttatgc tgaaatcttc
    10981 cagcgcaaca tcatggcttc gggtgtcatt ccacagattt caggtatttt cggtccgtgt
    11041 gccggcggtg cggtttactc tcccgccctg acagacttca cgctgatgac ggaaggtaca
    11101 tcttacatgt tcctcaccgg accggctgtt gtgaaaacag taacgggtga agacgtgtct
    11161 caggaagatc tgggtggtgc aagcgtacat gccagcaagt ccggtgtaac tcacttcact
    11221 gccgaaaccg gtgaagaagg tctggcgatt attcgcaagc ttctcagctt tattccgcaa
    11281 aacaacctgg aagaagctcc attggtgaac tgtaccgacc ccatcgaccg tatggacgac
    11341 ctgctgaacg agatcatccc cgacagcccg aacaaaccgt acgatatgta cgaagtgatc
    11401 ggcgccatca tcgataacgg agaattcctg gaagtacaga aagactatgc gaaaaatctt
    11461 attatcggtt ttgcccgtat gaacggacag tcggtaggtg tggttgccaa tcagcctaaa
    11521 tacctcgccg gagtactcga cagcaatgct tcacgcaaag gtgcacgctt cgttcgcttc
    11581 tgcgacgcat tcaacattcc gctggtgaca ttggtagacg ttccgggatt ccttccgggt
    11641 acgggtcagg aatataatgg tgtaatcctg cacggagcca agttgctgta cgcttatggt
    11701 gaagccactg tgcccaaggt aactgttacc ctgcgtaaat cttacggtgg ttcgcacatc
    11761 gtaatgagtt gcaagcaact ccgcggtgac atgaactatg catggccgac agccgaaatc
    11821 gccgtaatgg gaggtgccgg tgcagtagcg gtattgtatg ccaaagaagc taaagatcag
    11881 gaaaaccctg ctcaattcct ggcagacaag gaagccgagt acactaaact gttcgccaac
    11941 ccgtacaatg cagccaaata cggttacatc gacgacgtta tcgaaccgag aaacactcgt
    12001 ttccgcgtga tccgcgccct gcaacagctg cagaccaaaa aattaaccaa ccctgctaaa
    12061 aagcacggta atattccatt gtaacaaatt aaacatcgat tgttatgaat aagaaaagaa
    12121 tcgggatatt tatcgctctg ctggcaatgg tttgcatggg gctcagggcg caaagtgcca
    12181 ccagtctgag aatcaatgag gttttggtcg tcaacgacca gaactatcag gatgactacg
    12241 gactgcacaa tgcgtggata gagatattca acacctcttt cgcttctgta aatctggaag
    12301 gttgctttct gacgaacgat aaaaacaatc cgaccaaata tcctattccc aaaggcgacg
    12361 tgctgactct gatcaagccg cgccaacatg ctttgttctg ggcagacgga atgcctaacc
    12421 ggggtacgtt ccacgtgaac tttacgctcg acccgaacaa agagaattac attgctttgt
    12481 atgactctaa cggtaaaact ctgattgacg aagtaaccat ccccgccggt cagcttgccg
    12541 accgttcata cgctcgcgaa aaagacggaa gtgccaactg ggtagtaaaa ggtgaaggag
    12601 aacacagcta tgtcactccg agcaccaaca atatgactgt cgacaaaaac ccgaagatcg
    12661 agaacttcaa gaaacacgac tctatcggta tcggtatggc catcatcgcc atgtcggtcg
    12721 tattcatagg tttggtactc ttgtatcttt cattcaaggc ggtaggtaac gtagcggtca
    12781 gactaggtaa gaaaaacgcg atgaaagcca ccggtatcac cgacaagacg gaagcgaagg
    12841 aaaaaaacct gggtagccac acaggtgaag aaaccgccgc gatcgccatg gctttgcatg
    12901 aatacctgaa tgacgctcac gacgttgaag acatgatttt gactatcaac aaagtgaaac
    12961 gcacctactc cccctggagt tcgaagatct acacactgcg tcagactccg aaaagataat
    13021 tactaaccct aataaaatga agcaatgaaa caatataaat ataaaatcaa cggcaacctt
    13081 tacaacgtta cagtgaacga tgtagaagat aacatagcca acgttgaagt gaacggaacc
    13141 tcttataaag tagagttgga caagcccgtc aaagccgctc cgaaaccggt gacccgtccg
    13201 gcagccgctc cgaaaacgga aacaggtgct ccggtagtaa ccaaacaacc gacagcttcc
    13261 aaaaaagacg gtgtgaaatc tccgcttccg ggcgttatcc tcgacataaa agtgaaagaa
    13321 ggggataccg tgaagagagg ccagacaatc atcatccttg aggctatgaa gatggaaaac
    13381 aacatcaatg ccaataaaga cggaaaagta gcagaaatta aagttaataa aggagattct
    13441 gtacttgaag gtacagacct cgtaatcatt gaataattat gggagatttc gtatcattct
    13501 tagggaataa ccttgttgac ttctggggat acaccggttt tgcgaacgcg acacccggac
    13561 atcttttcat gttgctaatc ggtctcttct ttatctacct tgccgtagcc aaagaatttg
    13621 aaccgatgct gctgatcccc attggcttcg gtattctgat cggtaatatt ccattcaata
    13681 tggaagccgg attaaaagtg ggtatttacg aagaaggttc ggtactgaac atcctttatc
    13741 aaggagtaac ctccggctgg tatccgccgc tcattttcct gggtatcgga gccatgacgg
    13801 acttctcggc gctgatctcc aaccccaaat tgatgctgat cggagctgcc gcgcaattcg
    13861 gtatcttcgg cgcgtatatc attgccctgc tcattgggtt cgaacccaac caggcgggtg
    13921 ctatcggtat cattggcggt gccgacggac cgacggccat cttcctttcg tccaaactgg
    13981 ctcccaacct gatgggtgcc atcgctgtgt cagcctattc ttacatggca ctggtgccgg
    14041 tgatacagcc acctatcatg cgtgcgctaa ccaccaaaca cgagcgtctg atccgcatga
    14101 aaccaccgag aatcgtatcg catacggaaa aagtaatctt ccccatcgtg ggtctgttgc
    14161 ttacatgctt cctggttcct tcgggtctgc ctttgctggg tatgctgttc ttcggtaacc
    14221 ttctgaaaga aagtggagta acccgtcgtt tggcaaatac ggccagtggt ccgttgatcg
    14281 atgtgatcac tatcctgttg ggactgactg tgggagcttc tacccaagct tcacaattcc
    14341 tcacctggga ttctatcttg atctttatcc tcggtgcatt ctctttcatc atcgcaacag
    14401 cgtcaggtgt catgtttgtc aaattcttca atctattctt gaagaaaggc aataagatca
    14461 atccgctgat cggtaatgca ggtgtatccg ccgtacccga ctcggcacgt atttcacagg
    14521 taatcggttt ggaatatgat ccgaccaact atctgctgat gcacgccatg ggtcctaacg
    14581 tagcgggggt tatcggttcg gctgtagctg ccggtatcct gctcggattc ctcatgtaaa
    14641 cgatattttt ttcattagta aggtagacgt ccttcttttc gcaaagaagg gcgtcttttt
    14701 tttgcgttaa tctatctaaa agatattacg aatctttcgt agaatggata tttttactaa
    14761 cttgcggaca ataaaacaat acgtcctatg agaacaagaa caatgaaacc actcttcctt
    14821 attttctgtc tttgcctcag tcccctactg atgggccaga atcaaaacaa aattcaggaa
    14881 gcaatggcaa actatgacta cgagactgcc gttgaactga taaacaagga acctcccacc
    14941 atcccactgt taatgcagaa agcaaaagcc ctgaaaggaa tcggcagcaa tgcggaagct
    15001 ctacgttcca tccgccaagt gatagcggaa gactccacca accaacaggc acacatcgaa
    15061 gcagcggaat gctgtaaagc aatggccaag tacaacgatg cgctggacta ctaccggaaa
    15121 gccatcagcc tgaatcccaa aaacaagtat gcccgtttgc aattcatcaa cctgctttgc
    15181 aacaccaaaa actatgctga ggcttttgga gaaagttcaa tgatgtccga aacggacagt
    15241 tcggccgtag tgctccacct acaggctcaa agccttgaag ggatgcaaca gatactaccg
    15301 gctatcggtt gctatgaagt cattcaggat aaatatccgg acgattatct ggctgcggcc
    15361 aaactcggaa acctgaacat tgtggctgga tatcccgaat atgccatcca agctaccgaa
    15421 cgctataggg aacgggactc caccaacctg attgtcaacc agcaaaacgc tctcgcctac
    15481 tgccacgccg aacaatatcc gacagccatc aagcgctatg aaaagctgtg ccaacagggg
    15541 gacagcagta cacagacctt atactacctg ggagtcagct attacgcgga tgaatattat
    15601 tacgaagcgc acgcgtgttt cagcaaactg caaaaagaga tggaagaaaa tcccaatctg
    15661 ctctattatc tgggacgttg ctgcgccaag acttcctgga aaaaagaagg catcgaacac
    15721 ctggagaaag ctatcgaact gaccattccc aaagacagca ccatgatccg actttacaaa
    15781 ggcttggtgg attgttgtaa actggctcag gatactccaa agcaaatcca ggctctcaga
    15841 gaactgtaca aatatgacaa gacgaaccat aaacttcttt atgacatcgc ctggaactat
    15901 tcatatcaac tcaaagacaa caaatcggcc gaacgttatc tgcaggcttt cttaaaaacc
    15961 cgaaaggcga atgccaggaa agaagaaccg gtgagtgaga aaggggaact tgtactcgga
    16021 cttgaaaatt attacaacgc tgccgaaaat tggctgaaag acttacagaa agaaaagttc
    16081 ttcaaagaag gaataccgtt agaaagtcag aaacaataga atctatcccc catgaaacat
    16141 tggatactcc tcctctatct gggcttcagc gtaatgctgc gagcccagaa caccgcctcc
    16201 gttcaagaag caatggcaaa ctatgactat aaaacggtga tcagactgat tgatgaagaa
    16261 agtgcatcac cacagttact catacagaaa gccaaagctt taaaaggttt agggcgtacc
    16321 gccgaagccc tgtccacttt gcaacatatc attatcgagc tgcccaaaaa tcagcaggca
    16381 ttggtagagg cagcagaatg ttgcaggcaa ttgagcaaat ttaacgaggc cttggggtat
    16441 tatcggaagg tgatggaact caatcccgaa catatttacg cacacttgca atacacccgc
    16501 ttgttataca actatcagcg atacggcgat gcattgcgtg agagtatcgc attggccagg
    16561 aaagacagtt ccgccaccgt attgcgactg atggcggaaa gcatggaagg agccggcatg
    16621 ccggtagaaa gtatgttttg ctatctttcc atcatcagga aatatccctc cgactatctc
    16681 tcggtagcta agctgggcag tatcttcaat acaatgaaag attacgaagg ggcaattgcc
    16741 ctgacagagg cataccgccg gacggacagc accaatgtag aagtgaaccg tcaaaacgca
    16801 ctggcgtatt gtctgcgcaa agaatatccc accgccatca aacgttatca ggatctgacc
    16861 gcccggggag acagcacact gctgacatgt tattatctgg gagtcagcta ctacgctacg
    16921 aaagaatact ataaagcacg cgattggctg ctcaaagcaa aatcatgcca gtcacccggc
    16981 gccaacctac tctactattt gggacgttcg tgctccaaga cattatggaa acaagaggga
    17041 ataggatatc tgaaccaggc tatcgccctg actatccccg ccgacagtat catggagcgc
    17101 ttatactcag gcttggcaga ctgctacagg caaaccaagc aaacccggga ccaaatcaag
    17161 gctaccaaag aacaatacaa atatgcccct gacaagcata ttttacttta taacttggcg
    17221 ttcttatcgg acaaaatagg agatactaaa gccacagagc attacttgca ggcttttctg
    17281 cgaacaaaat ccaaacaaaa tgcagtacta cagcagccgg atgatgacga agaagaaccc
    17341 gcaccctaca tagattacta caaaagtgcc accaataaat tggaaagcat ccgaaaagag
    17401 aaattcttaa agggagaaaa gtgaattgat cggatagatg catcgtttcg gacaattcac
    17461 cactgagtgt agacagagtt tcacagaggg agaataatgg aaaataaatt tgaagatgtg
    17521 cggtagaagg cacagtggca cgtagccgaa gtcacatcgg cacgcagccg aaattacggt
    17581 gctgcgtagc cgaagttacg gtgctgtgta gccaaagtta cggtgctgcg tagccgaagc
    17641 tatgacggca tctccttttc cggacgtcac gttcacctga ttgcatcgaa aagtgctcct
    17701 tatcggttga gctccatccc ggagaattct ccaatgaaaa cgtttgcata aatagatggc
    17761 acacagtaag aaagaaaacg gaaaacaatc cgatgattta ccctatatta gcaacattaa
    17821 ataataacga gctaatatca tgaaaaaatt attgttactc ttaggttcat tcctactgtc
    17881 attaaccact tatgcagcca tgaacatatc taaaatcgat ccgcccttct ggttcaccgg
    17941 tatgaacaat ccggaactcc agttaatggt atacggtgaa ggcatcggcc aggcatccgt
    18001 atcagtaaat tatcccggtg tatcgctcag cagcgtcgtg aaactggaaa gcaacaatta
    18061 cctgcttgtc tacctacatc tcgataaaga agtaaagccg ggcaagatgc ccatcacatt
    18121 tacggtcgga aagaagaaat tggtgaaaga gtacgaattg aaagcacgca gcaaagccgg
    18181 agtcgatcac aaaggttttg acgcatcgga tgcattatac ctgctgatgc cggaccgttt
    18241 tgccaatggc aatccggata acgaccggat agaaggcatg gccgaatata aagtggaccg
    18301 caacgacccg aacgcacgtc acggaggcga cctggccggt atcgaacaaa atctggacta
    18361 ttttaccgat ttgggagtca ctgcactctg gttcaccccg gtactcgaaa ataacatgaa
    18421 aggcggctca tatcacggat atgcaacaac cgattattac aaggtagacc cacgtttcgg
    18481 cactaacgag gaatatcgct cactgatagc gaaagcccac aaccggggca ttaaggtcgt
    18541 gatggacatg atcttcaatc attgcggagt agaacatccc tggatcaagg acatgccttc
    18601 aaaggactgg ttcaaccatg cggacttcaa gaacaacttt gtgcaaactt cctacaagct
    18661 gactccacat gtagatccgt atgcctcgga gtacgatttc gaccagatga acaacggctg
    18721 gttcgtggaa gccatgcctg acctcaacca aaagaaccct cacgtataca aatacctctt
    18781 gcagaacagc ctgtggtgga ttgagtacgc cgatatcgac ggcatccgga tggacaccta
    18841 cccgtatgcc gattacgatg ccatgagcaa ctggatgaaa gaactgaacg aagaataccc
    18901 caactacaac acggtgggcg aaacctgggt taccgaaccg gcctatacag cctggtggca
    18961 gaaagactcc aagctctccg ccccgcgcaa cagtcacttg aaaacagtca tggatttcag
    19021 cttcttcgac aaagtcaaca cggccaagaa tgaacaaacg gacacttggt tcaaaggatt
    19081 ggaccgtgtc tacaacaatt ttgtatacga ttatctgtat cccaatccgg cttccgtact
    19141 ggctttcatc gagaatcatg acaccgaccg tttcctgggt gaaggcgaaa acctcgatat
    19201 gctgaaacag gcctccaccc ttttattgac cacccgacgc atcccgcaac tctattatgg
    19261 aacggaggtg atgatgaacg gagtaaagag taaaagcgac ggctatgtac gaaaggactt
    19321 cccaggcgga tgggcggacg ataaagagaa tgccctgact cccgagggac gtacccgatt
    19381 gcagaatgaa agctataact tctaccgcaa cctgctgaac tggcgtaagg gcaacgatgt
    19441 gatcgccaaa ggcagcatga aacagttcat ggtgcagcac ggcgtatatg cttatgcacg
    19501 ccaatataaa gggaaaacgg tattcgtcct gttgaacggt acggataaag aggtgaaact
    19561 tcccctgaaa tactatgccg aagtgctgaa agacaagact caaggaaaag acgtcattag
    19621 cggaaaagta acggcactca atgaagaact gacaatggca ccccgccaat cgatggttat
    19681 agagctttaa tctcacaccg gttataaccg cataagcaaa gggcacaaag gatttcaccc
    19741 gacatcctct gtgccctttg tgtagcctaa tgcgaataat aatagtcaaa cgtttgacta
    19801 ttatcgaaga atattcctac ctttgcaccg actaaaagaa tacgacgatg acaaacaacg
    19861 aatcggagcg cgagctcgtc ctacaaacct tacgaacctg gatggcattc cgccaggccg
    19921 ttcagcgggt actcaaacgt cacaacgtgg atatgacctt cgagatgctg caagtaatga
    19981 actgcctgtg gaacaaacaa ggcatcagcc agcaatccct ggctgagaaa acagcaaagg
    20041 acaaggcttg cctgaccaat ctgattaata atctggaaaa gaaaaactgg gtgatacgga
    20101 aggaaggccc ctccgaccgc cgaaaccgcc tgattttcct gacaccccaa ggcgaagaac
    20161 ttgccctcac cgtgaaaccc ctgatcaacg atatctatgc ccaaaccgga gcagagatgg
    20221 aggcaagccg gataacggaa tgcatcgaag acctgaagag actgcatgaa gtgctcaatg
    20281 agatctaaaa gaaatccgcc atgtccaccc gtcagataaa gctaaaacaa ttgagaagac
    20341 tgaagttcag gaacatcttt ctcaacacag tatgcatcct gctggcattg gcaggtattt
    20401 catggacagt aaactacttc tggaaatacg cccgctacga gataaccaat gatgccgtag
    20461 tggatcaata catcgctccg ctaaacatcc ggataccggg ctatatcaaa gaagtacgtt
    20521 ttaccgaaca ccagtatgtt catgccggcg acacgttact gatactggac gaccgggaat
    20581 accggatccg gctgaaagac gcggaagcgg ccttgatgga tgccttggga tcaaaggaag
    20641 tgttaaactc cggcatccgg acttcaggag taaatgtagc cgtgcaggaa gccaacatag
    20701 ccgaaacact ggcacacctt tcacagcaag aagcggaact gaaccgatat acccggctct
    20761 tgaaaaagca ggccgtcagc caacaggatt atgaactggc caaagcgaac ttcgaagcga
    20821 ctcaggcaag atacaacgcc ctgttgcaac aaaaagaagc ggcccaatcg cagtattccg
    20881 aaaccagcaa acgcagtaca ggcgccgaag ccaatatcct ccggaaggag gccgacctgg
    20941 agatggcccg actaaacctg tcgtataccg ttgtcaccgc accctatgac ggatacacgg
    21001 gacgacgtac acttgaaccg ggacagttcg tacaaggcgg acaaactctt tcctacctgg
    21061 tacggggcaa tgacaagtgg gtaacagcca attataaaga gactcaaata gcccatatct
    21121 atatcgggca aaaagtccgc atcaaagtag atgctttcag cggacgcact tttcacggga
    21181 ccgtaaccgc catttccgaa gccaccggat cgaaatactc cctggtacca accgacaatt
    21241 cggcaggaaa cttcgtcaaa gtacagcaac gcattccggt ccgcatcgat ctcaatgacg
    21301 cctcacccga agagatggaa tgcctccgtg cagggatgat ggtagaaacg gaggcggtcc
    21361 gcccttaggc ttatggtgaa gctcaatctg cctacccgtc cctgggtgcc tcaatggttg
    21421 ggcatcgtga ccatgtttat tgtcatcttt cccatcaccc tgctcaacgg tgcctacaca
    21481 ggaagtatgg tcgaagtatc gaacacgctg ggagtattga gcgaagatat taccatggct
    21541 tactattcag cttcggtagg gatggctgtt gcctatccca tcgtaccgaa aatacgcacc
    21601 atagccactc cgaaaacctt actgcttacc gacctgctgc tacagatatt cttcagcctg
    21661 gtatgcgcca aaaccggtag tatggacgtc atcatggtat gcagtttctg tatgggattt
    21721 ctcaaagcct tcgtcatgtt ggagttcatc atcctgatcc gcccgctctt cagtccgaaa
    21781 aacgtacgaa gtgaattcta tgcctacttc taccccatcg ttttctccgg aggtcagcta
    21841 tcgatggcta tcaccgctca actggcctat cactaccaat ggcagcacat gtactatttt
    21901 gtcaccatcc tcttgctgat cgccattctg ttcatcatct gtttcttccg ctatgcaagg
    21961 cgtcccatgc acattccgtt caaagagatg gacggaagaa gcatgttcat catcgccacc
    22021 gctttcctgc taacgctcta tacatttacc tacgggaaaa cactcgattg gttcgcatcc
    22081 ccgaagatca gagtatatgt attcgtcatc ccgctcctga tagctctctt catccatcgg
    22141 cagcgtacac aaggcaaacc ctttgtcagc ctgaaaccac tctttctgca taaatccatc
    22201 atcggatata gcttcatggt actcgccatg ttcctgacag ccaccagttc actggtaacc
    22261 aactatatga acagcatcat ccgggtagac agcatacacg ccaattcgct gagcctgtgg
    22321 ctattgcccg gatatgtggt aggggccgtc atttgcttct ggtggttccg atggcaacga
    22381 tggcggtttc gcttcctcat ttcaggaggt atgttctgct acgtcatcta tctggctatc
    22441 ctctactttg gtatcacccc ttatggaact tatgaaatgc tctacctccc catcctgttc
    22501 cggggagtgg ggatgatggt catattcatt gcgttcggtg tgtttgttgt cgaagattta
    22561 gacccgcgcc tgacgttgtc caatgccttc ttcctgattt cattccgctc agtattagct
    22621 ccggtcctgt ccgcttcgtt ctttaacaac atgctttact atctgcaggc aaaggggatg
    22681 aacattcttt cggaaaacat gacgctgacc aatccgctgg ccgaacaaaa atacaatcag
    22741 gcattgagca atgccctggc gcaagggcac gaattcagcg aggccggaca attggcagcc
    22801 aacagtctgt actccacttt gcagcagcaa tccctgctgc ttgccctgaa aaccctaatc
    22861 ggctatgtac tgatactggc actggtgatt gctgtcatcg cagcgttcat tcctttccat
    22921 aaaacgctga aggtggctgt agtgaagacg ggtgacgata tggtataatg agaagggata
    22981 ccaaaaagcc acccaattgc ttgagtggct tcttaaaata taaattaaat caagtaaaac
    23041 ttttaaatac tagatttgga atttattcag ctaacttgtt gtcagaaccc agcacgttga
    23101 taattttgtg cttgtagagt ttttccatat tgtcgcgagc cggtcccaga tatttacgcg
    23161 ggtcgaactc agccggtttt tctgcgaata ccttacggat agcagcagtc atagccagac
    23221 gagagtctga gtcgatgttg attttgcaaa cagcagactt agcggcttta cgcagttcct
    23281 cttcaggaat accgatagca gctttcagtg caccaccaaa ctggttgata gttgcaacct
    23341 cttcttcagg aactgaagat gatccgtgaa gaacgatagg gaatcccgga agttctttca
    23401 ttacaccgtc caatacgtcg aatgccaacg gaggaggaac catacggcct gtcttcggat
    23461 cgatgtggca ctgttccgga gtaaatttgt aagcaccgtg agaagtaccg atagagatag
    23521 ccaatgaatc gcaacctgtc ttggtaacga aatcaactac ttcgtccggt tcagtatatg
    23581 tgtggtggtc agaagaaact tcgtcttcta cccctgccaa tacgccaagt tcaccttcta
    23641 cagttacatc gaactggtga gcgtattcaa caactttctt agtcagagca acgttttcgt
    23701 cgtaaggaag gtgagaaccg tcgatcatta cagaagagaa gcctgagtcg atacagcttt
    23761 tgcaagtttc gaaagtatct ccgtggtcga ggtgcaaaac gatttcagga tttttgcagc
    23821 cgagttcttt tgcatattct acagcaccct gagccatgta acgcaacaat gtagcgttag
    23881 catactgacg agcacctttt gatacctgca aaataaccgg agacttagtt tctacagcag
    23941 ccttgatgat agcctgcatc tgttccatat tgttgaagtt gaatgcaggg attgcatatc
    24001 cacccttgat agccttagca aacatatctc tagtgtttac cagacctaaa tctttgtaat
    24061 taaccatttt gtttaaaagt ttattgttag tgaattaaaa attctatgca aaagtaagaa
    24121 taatcctttg aatagagaaa ccctcgggcg gaaatatccg tttgaggagc gtaattcaat
    24181 tctatttcaa attatttccc atcctttaag agctgtttgt aatgtctacg tagcaaataa
    24241 aggtttttta ttgtttcctc atatatataa tggtaggcaa atgatcgctg taaccatcca
    24301 accacactct gccaccatat gtacgcaggg gtgcaccctt atatttacca tcctgctgaa
    24361 acaggtaatc gcgcatgaaa acttcattgt gatcatattt caatcctttt gttgcttgaa
    24421 gcagagtggg tgaaaggatg atctgatcga acagattcca tttgcctcga tagagcaaag
    24481 tgcccactcc cttatcttcc agcgtcaccc accaggggtt gtaaaggtca tcttcagtca
    24541 tatcttcgac gtgtttcttt gcccccagta cggcaaggct caagtccatc ggatcgtcgt
    24601 tgaggtcgcc catgataatc agtttcaagt ccggatccg
//
