LOCUS       gnlProkkaDHBAMGME_27    8247 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DHBAMGME_27.
ACCESSION   gnlProkkaDHBAMGME_27
VERSION     gnlProkkaDHBAMGME_27
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 00:14:27
            Original ID  :: gnl|Prokka|DHBAMGME_27
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8247
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..333
                     /locus_tag="ctg26_1"
                     /transl_table=11
                     /translation="MTKDRAWSITKDDHVPLYYMKDLYTHTLLIVPNKQMEDFKFVMDL
                     APENVTFDDLPLTIGTKVQVVKGEFCGIEGELSSLANRTYVVIRIHGVLSASVKVPKSY
                     LRILSA"
     protocluster    1..8247
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[845:7869]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      846..7869
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..8247
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8247
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             353..826
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MNQVQNLQHIARELLYLGMDGSPIYTDHFRQLNTEVFRLSEALFS
                     MKGTTSEEEAAICLSLLMGYNATIYNDGDKESKIQSILDRSFAVLDHLPASLLKCQLLT
                     YCYGEVFEEDLAQEAHQIMDSWKNRALSEEELEVMETLQTMEDNRYPCSEVED"
     CDS             846..1733
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 271; E-value:
                     1.9e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.8e-14, bitscore:
                     41.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLYPITKGISKQLLPIFDKPMIYYPISVLMLAG
                     IRKILIISTPYDLPGFQRLLGDGSDFGVHFLYAEQPSPDGLAQAFIIGEEFIGDDSVCL
                     VLGDNIFYGQSFTRMLQEAVRTVESENKATIFGYWVKDPERYGVAEFDNDGNVLSIEEK
                     PDTPKSNYAVVGLYFYPNRVVKVAKNITPSFRGELEITTVNQHFLLDQKLKVQLLGRGF
                     AWLDTGTHDSLSEASTFIEVIEKRQGLKIACLEGIALRQGWISSEKMKVLAQPMLKNQY
                     GQYLLKVIDELSVK"
     CDS             1744..2298
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_4"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 4.5e-73,
                     bitscore: 234.0, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEILKTTIEGLIIIEPKLFWDGRGYFFESFNQKEFEEKVCKIVFV
                     QDNESKSHYGVIRGLHFQKPPFAQSKLVRVIKGAVLDVAVDIRKGSPTFGKYFSVELTE
                     DNHRQFFIPRGFAHGFSVLSEEVIFQYKCDNFYHPEAEGAIVWNDTELKIDWKIPIEKI
                     TLSEKDKAYPNFMDQDFHFNY"
     CDS             2305..3588
                     /locus_tag="ctg26_5"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             3602..4300
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_6"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             4320..5621
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_7"
                     /sec_met_domain="CTP_transf_like (E-value: 2.5e-13,
                     bitscore: 39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.2e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 4.6e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             5633..6769
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_8"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             6766..7869
                     /NRPS_PKS="Domain: Aminotran_5 (30-298). E-value: 6.2e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg26_9_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_9"
                     /sec_met_domain="Aminotran_5 (E-value: 7.7e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAVKFVK"
     aSDomain        6856..7659
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg26_9_Aminotran_5.1"
                     /evalue="6.20E-34"
                     /label="ctg26_9_Aminotran_5.1"
                     /locus_tag="ctg26_9"
                     /protein_end="298"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQS"
     CDS             7880..8245
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="MEDLNRYNKEGSDLRKLQYRMLELLEVLDKICKKHNLPYWLEGGT
                     LLGAVRHGGFIPWDDDLDVQMLRSDYKKLLKILPKELPGNIALQTFKTDKGYYRYVAKL
                     RDLNSKLISTSVDYKDCK"
ORIGIN
        1 accacgaaag accgtgcctg gtctatcacg aaggatgatc atgttcctct ttattatatg
       61 aaggatctct atacccatac tttgttgatc gttcccaaca aacagatgga agatttcaag
      121 tttgtgatgg atttagctcc ggaaaatgta acttttgatg atcttcccct taccattggt
      181 acaaaagtgc aggtcgtcaa aggagaattt tgtggcattg agggcgaatt gtccagcctt
      241 gccaaccgta cttacgtagt gattcgtatc cacggagttc tttctgccag cgtcaaagta
      301 cctaaaagtt accttcgtat tctttcagcg taattcgtaa tttcaaaatt atatgaatca
      361 agtccaaaat ctgcaacaca ttgcccgtga gttgctttat ttgggtatgg atggttctcc
      421 catctatacc gatcatttcc gtcaactgaa caccgaagtt tttcgcttgt ccgaagccct
      481 tttctctatg aaaggtacca catccgagga agaagcagcg atttgtctgt ccctgttaat
      541 gggctataat gctaccattt acaatgatgg cgacaaagaa tctaagatac aaagcatttt
      601 agatcgctct tttgccgtat tggaccatct tcctgcttct ctattgaaat gccaattgct
      661 gacttattgc tatggcgagg tattcgagga ggatttagca caagaagcac atcaaataat
      721 ggatagctgg aaaaataggg cactttcaga agaagaattg gaagtgatgg agacattgca
      781 gacaatggaa gataatcggt atccgtgtag tgaggtagaa gattgataaa ataacatata
      841 aaaaaatgaa aggtattgtt ttggcgggtg gttcaggaac acgtttatat cctattacta
      901 aaggaataag caagcagttg cttcctattt ttgataaacc gatgatttat tatcctattt
      961 cagttcttat gttagcagga attcggaaaa tattaattat ttctactccg tatgatttgc
     1021 caggatttca acgtttatta ggtgacggct ctgactttgg ggttcatttc ctttatgctg
     1081 agcaaccttc tcctgatggc ttggcgcagg cttttattat tggtgaagaa tttataggag
     1141 atgactcagt atgtttggtt ttaggagata atatttttta tgggcagagt tttactcgta
     1201 tgttacaaga ggcagtccgt acagtagagt cagaaaataa agcaaccatt ttcggttatt
     1261 gggtgaagga tcccgaacgt tacggtgtag cagagtttga caatgatggc aatgtactta
     1321 gtatagaaga aaaacctgat acacctaaat ctaattatgc cgttgtagga ctttattttt
     1381 atccaaatag agttgttaaa gtggcaaaaa atataactcc ttctttccga ggagaattag
     1441 aaataacaac tgttaatcaa cattttcttt tggatcaaaa actaaaggtt caattattag
     1501 gccgtggttt tgcttggtta gatacgggta cgcacgactc tttatctgaa gcaagtacct
     1561 ttattgaagt gatcgagaaa cgtcaaggtt taaaaatcgc ttgtttggaa gggattgcac
     1621 tgaggcaagg atggatttct tcggagaaga tgaaagtatt agcacagcca atgttgaaaa
     1681 atcaatatgg ccaatattta ttgaaagtta ttgatgaatt atcagtaaag taaatgtctt
     1741 tttatggaaa tattgaaaac gacaatagaa ggacttatta ttattgagcc taaacttttt
     1801 tgggacggtc ggggctattt ctttgaatct tttaatcaaa aagaatttga agagaaagta
     1861 tgtaagattg tgtttgttca agataacgaa tccaagtctc actatggcgt tatacgcggt
     1921 cttcatttcc agaaacctcc ttttgctcag agtaaattag ttagagttat taaaggggct
     1981 gttcttgatg ttgcagttga tattcgtaaa ggttcaccga catttgggaa atatttttca
     2041 gtagaactaa cagaagataa tcatcgtcag ttttttattc caagaggatt cgctcatggc
     2101 tttagtgtat taagtgaaga ggtcattttt caatataaat gtgataattt ttatcatccg
     2161 gaagcggaag gggcgattgt ttggaatgat acagaattga agattgattg gaagatacca
     2221 attgaaaaaa ttacattgag cgaaaaggat aaagcatatc ctaatttcat ggatcaagac
     2281 tttcatttta attactagaa gataatgatt cgttcctttc tttcccgttc tcccctttac
     2341 gttttggctc tctatgccag cgttttgatt tttctggttt atacttgtgc ctatgcctac
     2401 cgtaagccat ttaccgcagc catttatgaa ggtgagattc tttggggatt cgatgtcaaa
     2461 atcctgtatg tcctttctga gattatcggc tacgcccttt ccaagttcat cggtgttcgt
     2521 attctgcctt cgatgaaagc gggtcaccgc atctattata taatagggct gcttactttt
     2581 tccgaagttg ctttgttggg ttttgcactt cttccggttc ctttgaaggt gtgttctatt
     2641 tttctgagcg gtcttcccct gggtatgatc tggggtgtca tttttagcta tatcgaagga
     2701 cgtcgtatca gtgaaatatt gaatgtcggg ctgagcgttg ctttgatagt ctcttccggt
     2761 ttggtgaaaa ccttgggaca attcgtgatg gataatttgc atgtgtcgga atattggatg
     2821 ccttttacca ccggtttgtt ggtataccct gttatgttgc tttgcagctg gcttctcaat
     2881 cagattccgg ctcccaatga gcaagatatc atacagcgta ccaaacgtgc tccgatggat
     2941 ggtaaagaca ggcgtaaatt tttgaggcaa ttcttttggg gaatctgcat gctggttgtt
     3001 ttttacggtg ccctgaccgt gttccgtgag cttcgtgact ctttcgctgc cgatatttgg
     3061 aaggagctcc atattgaggg tgcaatgatc tttactcaga cagaggttcc cattgccgtt
     3121 tttgtccttg tactgatgtt cctgattgtg tttgtccgta ataaccgttt ggctcttaat
     3181 atcatttatt gcatcgccgt cacaggcggt tccttaatgg ttttttccac attgctttat
     3241 gtgtacggtt ttctttctcc tatttggtgg atgattcttt ccggtcttgg tctgtatatg
     3301 gggtatattc ctttcactta cctgatagaa cgtctgattg cttcccttag ggtggttagt
     3361 acggctgttt ttattattta tttggccgat tctttcggct atctgggcac tacgggtgtg
     3421 tttatggtca agaacttcgt ttctgctgac atttcctgga ctgtcatgct gatgcgtact
     3481 gccctttttt caggatttgt ttctgtcctg tcgatttttg cgatttactg ttatttcaag
     3541 caacaattga attcacttat attaattccc tctgaaattc atgattaaaa cagcaatgat
     3601 catggctgcc ggtcttggta cccgcttcgg gcattatacc gagcttgtgc ccaaaggttt
     3661 tgtggaggtt ggtggaaaac ctatgattat ccgctctatc gaaacccttc tttcctgcgg
     3721 tatcgaacgt atcatcctcg gtacgggtta taaaaaagag gcttatgaag cccttcaggc
     3781 ggatttcccc cagatagaga cctgtttcag tccccgttat gccgatacta acagtatgta
     3841 cactctgtac aatacgcgtg acgtgatagg cgatgacagt ttcctgctgc ttgaatcgga
     3901 ccttgttttt gaacgcaagg ccatcctctc gctgctggat gacgaattcc cggatgtgat
     3961 gcttgtctct tctctgacca agttccagga tcagtattat gtggaatatg accgcaatca
     4021 catccttact tcctgttcgg tagacaagga cgcccttgag gcaaaaggcg agctggtcgg
     4081 tatccataaa ctttccaata ctttctaccg ccggatgtgc gccgattatg cgaccatcct
     4141 ggagtcccag cctaaactgg gttacgagta cgaactgctc cgcatgtccc gttccgtttc
     4201 ccctgtccgt gtgctcaggg tggagggtct taaatggtat gaaatcgatg atgaagccga
     4261 cctttcgtat gctgaggagc acatcatccg ctattgttaa aaacaaatct tttccatata
     4321 tgaacaagaa aatctatgtc ggtatgaccg cggatatcat gcatccgggg ttgatccata
     4381 ttattcatga agctactaaa tacggtgatg tcatcgtcgg tctgctgacg gacaaggcca
     4441 tcgccgaaca caaacgcctc ccttacctta cctatgatca gcgtaaggag gttgttgaga
     4501 atatcaaagg ggtttgcgaa gttgttcccc aggaggattg gagctatgtt ccgaatctgg
     4561 aaaaactcaa gcctgactat atcatccacg gcgacgactg gaaaacgggc ccgttgcgcg
     4621 aggtgcgcga acaggttttt gaggtgatga acgcccaggg gggcaaggta atcgagatcc
     4681 cttatacccg gggcatcaac tcctcctcgc tcgacaagga tatcaaggcg atcgggacta
     4741 cccctgacgt acgtcttaag tccctccgcc gcctgatcca ggccaagcct gtggtccgta
     4801 tcctggaggc tcacgacggg ctttgcggtc tgattattga gaatcttgaa gtccagaagg
     4861 gtgataagcg cgaggtcttt gacggcatgt ggtccagcag cctgaccgac tccacgagta
     4921 agggtaaacc ggatattgaa gcggtcgacc ttaccacccg tttacaggac ctgaacaata
     4981 tccttgaatg caccaccaag cctattattt ttgatggaga cacgggtggc aagatcgaac
     5041 actttgtctt tactgtgcgc actttggaac gtcacggcat ttctgcggta atcattgaag
     5101 ataaagttgg tctgaagaag aattcccttt ttggtactga cgctatccag actcaggata
     5161 gtatcgaggg tttctgcgat aagatcagag cagggaagaa tgcccaggtc accggtgact
     5221 ttatgatcat tgcgcgtatc gaaagcctta ttgccggcaa acccatgagt gacgccctcg
     5281 aacgtgctta tgcctatgta caggcgggtg cggacggcat catgatccac agcaaggata
     5341 agtcgggtga ggatatccgt gagttctgcc ggactttccg caaagaatac gcccatgttc
     5401 ccattgtcgt tgttccgacg acttatgacc atgtgcacga atccgaactt cacgaatggg
     5461 gtgccaacgt agtcatttac gccaaccacc ttctccgtgc cgcttatccg gccatgatga
     5521 acgtggccag gaccatcctt gaaaacgagc gcgccgagga ggtccgtccg ctttgtatgc
     5581 ctatcaagga aattctggaa ttgattccgg gcactaaata aatcagacgg ttatggtaag
     5641 tgtagaaaag atatacgata cgttccttca tcacggtgtt gacttcttta cgggtgttcc
     5701 cgattccctt ttgaagaata tttgcgccta tatcacggat catgctccgc gtggtaagca
     5761 tatcatcgcc gccaatgaag gttccgcggt gggcattgcc tgcggttatt atatggcttc
     5821 tggcaacgtt cctttggttt atatgcagaa ctccggtctg ggaaatacgg tgaatcccct
     5881 cttgtccctt gcggacgaga aagtgtacag ccttcctctt cttttgctgg tcggttggcg
     5941 cggtgagccc ggcacgaaag acgaacccca gcataagaag cagggcgagg ttacccttga
     6001 tcttctgaaa gccatgaaaa ttccttttat aattctggat acggatgaag acgaggccct
     6061 ggcgcagatc catgacgcgg ttgtctcggc gaagagccgg tcgattcccc atgcgattgt
     6121 catccgtaaa gatacgtttg gaaaatataa attgcgtcag gaagccttga atgactatcc
     6181 tctgtcccgc gaggaggcgc taatgcaggt tgtcgaccac ctcggggaca atgacattgt
     6241 ggtttccacc acgggcaagc tctcccgtga gcttttcgag taccgtgaat cgaaagggca
     6301 ggggcacgca agggatttcc taactgtggg ttccatgggt cacagttctt ccattgccct
     6361 ggggattgcc cttgagaagc ctgaccgccg tgtctactgt cttgacggtg acggtgcctt
     6421 tatcatgcac atgggtgctg tcagcaatat cggcgatctt tctcccaaga attacaggca
     6481 cgtccttttc aataacggtg cccatgaatc tgtcggcggt caacccacgc tcggtttccg
     6541 tctggatatc gcctcgatag cgaaaggttg cggttatgcg catgtactga ctgcctccga
     6601 caaggaaggg ctttcgtgtg cgcttgagaa gctgtccggc ctgtccggcc cggttcttct
     6661 tgaaattaag gtccggatcg attcacgtga tgatctgggt cgccctacga ctactccggt
     6721 agagaataaa gagcatttta tggcattttt aaaagatacg cattcatgaa tatcgaaaga
     6781 aagatccttt tgaatccggg tcccgccacc acgacggata cggtgaagct ggcgcaggtt
     6841 gttcccgata tctgtccgcg tgagaaagag tttgcgggta tgatgaaaca gttacgtgac
     6901 gacctggtcc gcgttgcgca tggagacctc tccaaacata cggccgtcct gttttgcggc
     6961 tcggggacga tcaatatcga tatctgcctg aactctcttc ttcctgcgga taagaaagtt
     7021 ctggttgtca ataacggtgc ctacagcacc cgtgcggtgg aagtctgcga atattacggt
     7081 cttccccata tcgatttgaa gttttccgtt tacgaacttc ccgacctgtc ggtaatcgaa
     7141 aagacgcttt ccgacaatcc ggacatcgct ttggtctata ccacgcacca tgaaacgggt
     7201 acgggtatct tgaaccccat ccgtgagatc ggaaaaatag cccattcgca cggtgccgtt
     7261 tttgttgtcg acaccacttc ctccctgggt atgattcctt ttgatatcgg gaaggataat
     7321 gttgactttt gtatggcttc ggctcagaaa ggccttcagg ccatgacggg gctttccttt
     7381 atcataggtg atgaatccct gatacgtgct tcaagggatt atccgaaacg ttcctactat
     7441 tgtaacctct atttacaata cgattacttt gagaagacgg gcgagatgca ttttactcct
     7501 cctgttcaaa ccgtttacgc tgcccgtcag gctcttgatg aatattttgc agtaggtgaa
     7561 gaggctaaat tcgcccgtca caagagggtc tttgaagcca tccataaagg tttgcaagag
     7621 cttggtcttc agtatgcgat caaacgtgaa tggcagtcgg gtcttgttgt ttctgtattg
     7681 tatcctgatg atcccctctg ggattttgat aaggttcatg attactgcta tgaacgtggc
     7741 tttacgatct acccgggtaa gatttccaca acgaatacat tccggctttg tgcgttggga
     7801 gagattgatg tggaggatat tgagaggttc tttgaggtga tgagagaagc tgtgaaattt
     7861 gttaaataaa tttgtattaa tggaagactt aaatagatat aataaagagg gttcagattt
     7921 aagaaagctt caataccgta tgctggaatt attggaagtt ttagataaga tatgtaaaaa
     7981 gcataacctt ccatattggc tagagggagg gaccttatta ggtgcagtaa ggcatggagg
     8041 atttattcct tgggacgatg atttagatgt tcaaatgctt cgttctgatt ataaaaaatt
     8101 attaaaaata ctgcccaaag aattacctgg taacattgct cttcagacat ttaaaacgga
     8161 taaaggatat tatcgttatg tagctaaact aagagattta aattctaaat tgatttctac
     8221 atcggtagat tataaggatt gtaaatt
//
