LOCUS       gnlProkkaDHBAMGME_99    4083 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DHBAMGME_99.
ACCESSION   gnlProkkaDHBAMGME_99
VERSION     gnlProkkaDHBAMGME_99
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 00:14:27
            Original ID  :: gnl|Prokka|DHBAMGME_99
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4083
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..198
                     /locus_tag="ctg88_1"
                     /transl_table=11
                     /translation="MPSSLLKCQLLTYCYGEVFEEELAKEAHAIIDGWKDRELLEEERE
                     IVENLRILEEPPYLFSNKSC"
     protocluster    1..4083
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[200:3760]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      201..3760
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..4083
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4083
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             201..1502
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 200.2;
                     E-value: 7e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_2"
                     /sec_met_domain="CTP_transf_like (E-value: 8.4e-17,
                     bitscore: 50.2, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.4e-119, bitscore:
                     386.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 6.3e-65, bitscore:
                     207.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVYVGMSADIIHPGHLNIIHEAQKLGNVTVGVLTDAAIASYK
                     RLPYLTYEQRSLIVQNLKGVDEVIPQTTLDYIPNLELLKPDFVVHGDDWKEGVQKETRQ
                     RVIETLSKWGGQVIDIPYTQGISSTKLNSKLKEIGTTPEVRLKRLKRLIEAKSIVRICE
                     SHSGLTGLIIENTSVEVNGMKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDAL
                     ECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCDKISAGKRAQITDDFMIIARIESFIAGKGLDDAMKRALAYIEAGADGIMIHSKD
                     KSGEDIRLFCKALREVNQSIPIVVVPTTYNHITDEELSTWGINVVIYANHMLRSAYPAM
                     LNTAKSILLHARSYEANDLCMPVKDILELIPGTK"
     CDS             1510..2637
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 67.8;
                     E-value: 1.3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_3"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.4e-19, bitscore:
                     58.0, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.6e-22, bitscore:
                     67.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPELFINSLVQNELNFFTGVPDSLLKHICAYITDHIASNSHIV
                     AANEGAAIGLAVGYHLATNKIPVVYMQNSGIGNSINPLLSLVDKEVYNIPLLLLVGWRG
                     EPGVKDEPQHIKQGKVTIPLFDSMRIKNQILSKDKSDFLQQLNVALEYIRETNEPFVFI
                     IQKETFSDYKLQTPNNNALLLDRETAIKIIVSSISKNDIVVSTTGMISRELFEYRDNMG
                     ESHEKDFLTVGSMGHASQIALGIALQKKARTVYCFDGDGAVLMHMGGLTTIGSIKPSNY
                     IHVLFNNGAHDSVGGQPTVGFEVDFTKIALACGYKYALVVESASSLNEVLKTVNEMQGP
                     VFLEVKVKKGARKDLGRPTITPIQNKDSFMDFLKR"
     CDS             2639..3760
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_4"
                     /sec_met_domain="Fe-ADH (E-value: 1.2e-85, bitscore: 275.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQRIYIGEASLNNLDIILQEYSAKKVFLVRGKKSYELCGAQSRL
                     NSILKKVGVQIFEFHDFEENPKIEDLDRGLLQLRVYHPDLILAIGGGSVLDMAKLLRFF
                     YSYSGNKIGRVFEKIENLLPLIVIPTTAGTGSEATSFAVLYKNKVKYSVSHEDILPEIA
                     FIDPYFTYNISRYLTACTGFDALAQAIEAYWNLNATNESDVFAVKAIKLLWPNLPLAVN
                     NPTKEVRNSMSEGAYWAGCAINITKTTAPHAFSYPFTTYYGYPHGHAVALTFPFFMEYN
                     VGSILLKHGTVFDKMIRLMEILNITNVNECKSLLCDYIENIGLDLKLPANFDHRIILSN
                     INVQRLSNNPVRIDGAVAKTALNTLCIKDDDKD"
     CDS             3766..4083
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_5"
                     /sec_met_domain="Polysacc_synt (E-value: 2.9e-16, bitscore:
                     48.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKSLDSYKVIFQNTFYLSIIEAIRLIMPFIALPYIITTIGAT
                     NYGIIIFSQTIVSYFSIVINWGLDVTSVREVSLNRGSLKKMSLIVSTVFTIKFILFGLC
                     FS"
ORIGIN
        1 ctcccgtctt ctttgctcaa gtgtcagctt ttgacatatt gttatggaga agtttttgaa
       61 gaagagttgg caaaggaagc tcatgcaatt atagatggtt ggaaagatcg agaattgtta
      121 gaagaagaaa gagaaatagt tgaaaatttg aggattttgg aagaacctcc atatctgttt
      181 agtaataaat cttgttagaa atgaaaaaga aagtatatgt tgggatgagt gctgatatta
      241 ttcatccagg gcatttgaat attattcatg aagcacaaaa actagggaat gtgactgtag
      301 gtgttttaac agatgctgct atagccagtt ataaacgttt accttattta acttatgaac
      361 aacgttcctt aatagtacaa aatctaaaag gtgttgatga agttattcca caaactacct
      421 tagattatat tcctaatctt gaattgctaa aacctgattt tgttgttcat ggagatgatt
      481 ggaaagaagg cgttcagaag gaaacaagac aacgggttat tgaaactctt tctaaatggg
      541 gcggacaagt tattgatata ccttatacac aaggtatatc ctcaacaaaa ctcaattcaa
      601 agcttaaaga aatagggaca actcctgaag tgcgtttgaa aagattaaaa cgtttgattg
      661 aagctaagtc cattgttcgt atttgtgaat cacatagtgg attaacgggg ttaatcatag
      721 aaaatacgtc tgttgaggta aatggtatga agcgtgaatt tgatggaatg tggtctagta
      781 gtttaactga ttcaacatca aaggggaagc ctgatattga agctgtagat ttgacgaccc
      841 gtttacatga tttaaatgat gctttggaat gtacaacgaa acctgttatt tttgatggtg
      901 atacaggagg aaaaattgaa cattttgttt ttacagttcg tacgttagaa cgtttgggta
      961 tttctgctat aataattgaa gataaagttg gattgaaaaa gaattcttta tttggaactg
     1021 atgttattca gacacaagat acaattgagg gtttttgcga taaaatatca gcaggaaaac
     1081 gtgctcaaat aacggatgac tttatgatta ttgccagaat tgaaagtttt attgctggta
     1141 aaggtttaga tgatgctatg aaaagagcat tagcttatat tgaggcggga gctgatggta
     1201 taatgattca cagtaaagat aaatcaggtg aagatattag acttttttgt aaggcgttac
     1261 gagaggttaa tcaatcaatt cctatagtag tagttccgac aacttataat catataacag
     1321 atgaagagtt gtctacatgg ggtataaatg tggtcattta tgcaaaccat atgttacgta
     1381 gtgcttatcc tgctatgcta aatactgcga aatctatatt attacatgcc cgttcatatg
     1441 aggcaaatga tttatgtatg ccagtaaaag atatattaga attaatacca ggtacaaaat
     1501 agttttttta tgatttctcc agaacttttc attaactctc ttgtacaaaa tgaacttaat
     1561 ttttttacag gggtaccaga ctcattattg aaacatattt gtgcctatat aactgatcat
     1621 atagcttcaa atagtcatat agttgctgcc aatgagggag cagcgattgg tttggctgtt
     1681 ggttatcatt tggcaactaa taaaattccg gttgtatata tgcaaaattc cggtattggt
     1741 aattctatta atcctttatt atctttagta gacaaggagg tgtataatat tcctttatta
     1801 ttattagtcg gttggagagg tgagcctggt gtaaaggatg aacctcaaca tataaaacaa
     1861 ggtaaggtaa ctattccttt gtttgattct atgcgaataa agaaccagat actttccaaa
     1921 gataaatctg atttcttaca acaactaaac gtagcattag aatatataag agagacaaat
     1981 gagccttttg tttttataat tcagaaagaa acattcagtg attataaact gcaaactcca
     2041 aataataatg ctttgttatt ggatagagaa actgctatta agattattgt ttcttctatt
     2101 tctaagaatg atatagtcgt ttctactaca ggaatgatat ctcgtgagct atttgaatat
     2161 agggataaca tgggcgaatc tcatgaaaag gactttttaa cagtcggttc tatggggcat
     2221 gcctctcaaa tagctttggg tattgcatta caaaaaaagg ctagaactgt gtattgtttt
     2281 gatggtgatg gtgctgtttt aatgcatatg ggaggactaa caaccattgg atcaataaaa
     2341 ccgtctaatt acatccatgt attatttaat aatggagcgc atgattctgt aggtgggcaa
     2401 cctacggttg gttttgaggt agactttaca aagatagctt tggcgtgcgg ttataaatat
     2461 gctttggttg tggagagtgc ttcatcttta aacgaagttc ttaaaacggt gaatgaaatg
     2521 caaggacctg tttttttgga ggttaaggta aagaaaggtg ctcgaaaaga tttaggtcgt
     2581 cctacaataa ctccaataca aaataaagac tcttttatgg actttttaaa gcgataatat
     2641 gaaacaacgc atatatattg gagaggcctc attgaataat ttagatatta ttttgcagga
     2701 atattctgca aagaaggttt ttttggtgag agggaagaaa tcatatgagc tttgtggagc
     2761 acaatcaaga ttaaactcta tattgaagaa agtaggagtt cagatctttg aattccatga
     2821 ttttgaggaa aatcctaaaa tagaagattt agatagagga cttttgcaat taagagttta
     2881 tcatccagat ttgatacttg caataggagg aggcagtgta ttggatatgg ctaaattgct
     2941 tcgttttttt tattcttatt ctggaaataa aataggaaga gtttttgaaa aaatagaaaa
     3001 tctattacct ttaattgtta tacctacaac tgcgggaact ggcagtgagg ctacgagttt
     3061 tgctgtgtta tataagaata aagttaagta ttctgtttcg catgaagata tattacctga
     3121 aatagctttt attgatccat attttacata taatatttct cgatatttga cagcttgcac
     3181 ggggtttgat gcattggccc aggctattga agcttattgg aatttaaatg ctacaaatga
     3241 atctgatgtt tttgcagtaa aagcaataaa attactttgg cctaatttac cattagcggt
     3301 aaataatcca acaaaagagg ttagaaacag tatgtctgaa ggggcctatt gggctggatg
     3361 tgcaataaat ataacgaaga ctacagcacc tcatgctttt tcttatccat ttactactta
     3421 ttatggctat ccacatggac atgcggtggc attaactttc ccatttttta tggaatataa
     3481 tgtaggaagt atattattaa agcatggtac agttttcgat aaaatgattc gattgatgga
     3541 aatactcaat ataaccaatg taaatgaatg caaatcttta ctatgtgatt atatagaaaa
     3601 tatcggactt gatttaaagt tgcctgccaa ttttgatcat cgaattattc tttcaaatat
     3661 aaatgtgcaa aggttgagta ataaccctgt acgaatagat ggggctgtgg ctaaaacagc
     3721 tttaaatact ttatgtatca aggatgatga taaagattga tagtgatgaa aattaaaaag
     3781 tctttagatt cctataaagt aatttttcaa aatacatttt atttgtcgat aattgaagct
     3841 atacgcttaa taatgccctt tatcgctctt ccatatatta ttactactat tggcgcaact
     3901 aattatggga ttatcatttt ttctcaaacg attgtttcat atttttcaat tgttattaat
     3961 tggggattag atgtaacttc agtccgagaa gtgtctttaa atagaggtag tttaaaaaaa
     4021 atgagtttaa tcgtttctac tgtatttact attaaattta ttttgtttgg actttgcttt
     4081 tct
//
