LOCUS       gnlProkkaGPBAHGLE_43    4173 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPBAHGLE_43.
ACCESSION   gnlProkkaGPBAHGLE_43
VERSION     gnlProkkaGPBAHGLE_43
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 19:53:53
            Original ID  :: gnl|Prokka|GPBAHGLE_43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4173
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4173
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[130:3690]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      131..3690
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..4173
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4173
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..128
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="MEAHAIIDGWKDRELLEEEREIVENLRILEEPPYLFSNKSC"
     CDS             131..1432
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 200.2;
                     E-value: 7e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_2"
                     /sec_met_domain="CTP_transf_like (E-value: 8.4e-17,
                     bitscore: 50.2, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.4e-119, bitscore:
                     386.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 6.3e-65, bitscore:
                     207.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVYVGMSADIIHPGHLNIIHEAQKLGNVTVGVLTDAAIASYK
                     RLPYLTYEQRSLIVQNLKGVDEVIPQTTLDYIPNLELLKPDFVVHGDDWKEGVQKETRQ
                     RVIETLSKWGGQVIDIPYTQGISSTKLNSKLKEIGTTPEVRLKRLKRLIEAKSIVRICE
                     SHSGLTGLIIENTSVEVNGMKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDAL
                     ECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCDKISAGKRAQITDDFMIIARIESFIAGKGLDDAMKRALAYIEAGADGIMIHSKD
                     KSGEDIRLFCKALREVNQSIPIVVVPTTYNHITDEELSTWGINVVIYANHMLRSAYPAM
                     LNTAKSILLHARSYEANDLCMPVKDILELIPGTK"
     CDS             1440..2567
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 67.8;
                     E-value: 1.3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.4e-19, bitscore:
                     58.0, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.6e-22, bitscore:
                     67.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPELFINSLVQNELNFFTGVPDSLLKHICAYITDHIASNSHIV
                     AANEGAAIGLAVGYHLATNKIPVVYMQNSGIGNSINPLLSLVDKEVYNIPLLLLVGWRG
                     EPGVKDEPQHIKQGKVTIPLFDSMRIKNQILSKDKSDFLQQLNVALEYIRETNEPFVFI
                     IQKETFSDYKLQTPNNNALLLDRETAIKIIVSSISKNDIVVSTTGMISRELFEYRDNMG
                     ESHEKDFLTVGSMGHASQIALGIALQKKARTVYCFDGDGAVLMHMGGLTTIGSIKPSNY
                     IHVLFNNGAHDSVGGQPTVGFEVDFTKIALACGYKYALVVESASSLNEVLKTVNEMQGP
                     VFLEVKVKKGARKDLGRPTITPIQNKDSFMDFLKR"
     CDS             2569..3690
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_4"
                     /sec_met_domain="Fe-ADH (E-value: 1.2e-85, bitscore: 275.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQRIYIGEASLNNLDIILQEYSAKKVFLVRGKKSYELCGAQSRL
                     NSILKKVGVQIFEFHDFEENPKIEDLDRGLLQLRVYHPDLILAIGGGSVLDMAKLLRFF
                     YSYSGNKIGRVFEKIENLLPLIVIPTTAGTGSEATSFAVLYKNKVKYSVSHEDILPEIA
                     FIDPYFTYNISRYLTACTGFDALAQAIEAYWNLNATNESDVFAVKAIKLLWPNLPLAVN
                     NPTKEVRNSMSEGAYWAGCAINITKTTAPHAFSYPFTTYYGYPHGHAVALTFPFFMEYN
                     VGSILLKHGTVFDKMIRLMEILNITNVNECKSLLCDYIENIGLDLKLPANFDHRIILSN
                     INVQRLSNNPVRIDGAVAKTALNTLCIKDDDKD"
     CDS             3696..4172
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_5"
                     /sec_met_domain="Polysacc_synt (E-value: 1.8e-22, bitscore:
                     68.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKSLDSYKVIFQNTFYLSIIEAIRLIMPFIALPYIITTIGAT
                     NYGIIIFSQTIVSYFSIVINWGLDVTSVREVSLNRGSLKKMSLIVSTVFTIKFILFGLC
                     FSIFMICLFFIPFFQQYRIIYLYAFLSCFSEVIIPVWFFQGIEKMKYLTYIRTTS"
ORIGIN
        1 caaaggaagc tcatgcaatt atagatggtt ggaaagatcg agaattgtta gaagaagaaa
       61 gagaaatagt tgaaaatttg aggattttgg aagaacctcc atatctgttt agtaataaat
      121 cttgttagaa atgaaaaaga aagtatatgt tgggatgagt gctgatatta ttcatccagg
      181 gcatttgaat attattcatg aagcacaaaa actagggaat gtgactgtag gtgttttaac
      241 agatgctgct atagccagtt ataaacgttt accttattta acttatgaac aacgttcctt
      301 aatagtacaa aatctaaaag gtgttgatga agttattcca caaactacct tagattatat
      361 tcctaatctt gaattgctaa aacctgattt tgttgttcat ggagatgatt ggaaagaagg
      421 cgttcagaag gaaacaagac aacgggttat tgaaactctt tctaaatggg gcggacaagt
      481 tattgatata ccttatacac aaggtatatc ctcaacaaaa ctcaattcaa agcttaaaga
      541 aatagggaca actcctgaag tgcgtttgaa aagattaaaa cgtttgattg aagctaagtc
      601 cattgttcgt atttgtgaat cacatagtgg attaacgggg ttaatcatag aaaatacgtc
      661 tgttgaggta aatggtatga agcgtgaatt tgatggaatg tggtctagta gtttaactga
      721 ttcaacatca aaggggaagc ctgatattga agctgtagat ttgacgaccc gtttacatga
      781 tttaaatgat gctttggaat gtacaacgaa acctgttatt tttgatggtg atacaggagg
      841 aaaaattgaa cattttgttt ttacagttcg tacgttagaa cgtttgggta tttctgctat
      901 aataattgaa gataaagttg gattgaaaaa gaattcttta tttggaactg atgttattca
      961 gacacaagat acaattgagg gtttttgcga taaaatatca gcaggaaaac gtgctcaaat
     1021 aacggatgac tttatgatta ttgccagaat tgaaagtttt attgctggta aaggtttaga
     1081 tgatgctatg aaaagagcat tagcttatat tgaggcggga gctgatggta taatgattca
     1141 cagtaaagat aaatcaggtg aagatattag acttttttgt aaggcgttac gagaggttaa
     1201 tcaatcaatt cctatagtag tagttccgac aacttataat catataacag atgaagagtt
     1261 gtctacatgg ggtataaatg tggtcattta tgcaaaccat atgttacgta gtgcttatcc
     1321 tgctatgcta aatactgcga aatctatatt attacatgcc cgttcatatg aggcaaatga
     1381 tttatgtatg ccagtaaaag atatattaga attaatacca ggtacaaaat agttttttta
     1441 tgatttctcc agaacttttc attaactctc ttgtacaaaa tgaacttaat ttttttacag
     1501 gggtaccaga ctcattattg aaacatattt gtgcctatat aactgatcat atagcttcaa
     1561 atagtcatat agttgctgcc aatgagggag cagcgattgg tttggctgtt ggttatcatt
     1621 tggcaactaa taaaattccg gttgtatata tgcaaaattc cggtattggt aattctatta
     1681 atcctttatt atctttagta gacaaggagg tgtataatat tcctttatta ttattagtcg
     1741 gttggagagg tgagcctggt gtaaaggatg aacctcaaca tataaaacaa ggtaaggtaa
     1801 ctattccttt gtttgattct atgcgaataa agaaccagat actttccaaa gataaatctg
     1861 atttcttaca acaactaaac gtagcattag aatatataag agagacaaat gagccttttg
     1921 tttttataat tcagaaagaa acattcagtg attataaact gcaaactcca aataataatg
     1981 ctttgttatt ggatagagaa actgctatta agattattgt ttcttctatt tctaagaatg
     2041 atatagtcgt ttctactaca ggaatgatat ctcgtgagct atttgaatat agggataaca
     2101 tgggcgaatc tcatgaaaag gactttttaa cagtcggttc tatggggcat gcctctcaaa
     2161 tagctttggg tattgcatta caaaaaaagg ctagaactgt gtattgtttt gatggtgatg
     2221 gtgctgtttt aatgcatatg ggaggactaa caaccattgg atcaataaaa ccgtctaatt
     2281 acatccatgt attatttaat aatggagcgc atgattctgt aggtgggcaa cctacggttg
     2341 gttttgaggt agactttaca aagatagctt tggcgtgcgg ttataaatat gctttggttg
     2401 tggagagtgc ttcatcttta aacgaagttc ttaaaacggt gaatgaaatg caaggacctg
     2461 tttttttgga ggttaaggta aagaaaggtg ctcgaaaaga tttaggtcgt cctacaataa
     2521 ctccaataca aaataaagac tcttttatgg actttttaaa gcgataatat gaaacaacgc
     2581 atatatattg gagaggcctc attgaataat ttagatatta ttttgcagga atattctgca
     2641 aagaaggttt ttttggtgag agggaagaaa tcatatgagc tttgtggagc acaatcaaga
     2701 ttaaactcta tattgaagaa agtaggagtt cagatctttg aattccatga ttttgaggaa
     2761 aatcctaaaa tagaagattt agatagagga cttttgcaat taagagttta tcatccagat
     2821 ttgatacttg caataggagg aggcagtgta ttggatatgg ctaaattgct tcgttttttt
     2881 tattcttatt ctggaaataa aataggaaga gtttttgaaa aaatagaaaa tctattacct
     2941 ttaattgtta tacctacaac tgcgggaact ggcagtgagg ctacgagttt tgctgtgtta
     3001 tataagaata aagttaagta ttctgtttcg catgaagata tattacctga aatagctttt
     3061 attgatccat attttacata taatatttct cgatatttga cagcttgcac ggggtttgat
     3121 gcattggccc aggctattga agcttattgg aatttaaatg ctacaaatga atctgatgtt
     3181 tttgcagtaa aagcaataaa attactttgg cctaatttac cattagcggt aaataatcca
     3241 acaaaagagg ttagaaacag tatgtctgaa ggggcctatt gggctggatg tgcaataaat
     3301 ataacgaaga ctacagcacc tcatgctttt tcttatccat ttactactta ttatggctat
     3361 ccacatggac atgcggtggc attaactttc ccatttttta tggaatataa tgtaggaagt
     3421 atattattaa agcatggtac agttttcgat aaaatgattc gattgatgga aatactcaat
     3481 ataaccaatg taaatgaatg caaatcttta ctatgtgatt atatagaaaa tatcggactt
     3541 gatttaaagt tgcctgccaa ttttgatcat cgaattattc tttcaaatat aaatgtgcaa
     3601 aggttgagta ataaccctgt acgaatagat ggggctgtgg ctaaaacagc tttaaatact
     3661 ttatgtatca aggatgatga taaagattga tagtgatgaa aattaaaaag tctttagatt
     3721 cctataaagt aatttttcaa aatacatttt atttgtcgat aattgaagct atacgcttaa
     3781 taatgccctt tatcgctctt ccatatatta ttactactat tggcgcaact aattatggga
     3841 ttatcatttt ttctcaaacg attgtttcat atttttcaat tgttattaat tggggattag
     3901 atgtaacttc agtccgagaa gtgtctttaa atagaggtag tttaaaaaaa atgagtttaa
     3961 tcgtttctac tgtatttact attaaattta ttttgtttgg actttgcttt tctattttca
     4021 tgatatgttt gttttttatc cctttctttc aacaatatag aattatatat ctgtatgctt
     4081 ttttgtcatg cttttctgag gttattatac ctgtgtggtt ttttcaaggt attgagaaga
     4141 tgaagtattt gacttatata aggacaacaa gta
//
