LOCUS       c00002_gnlPro..        14884 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ELOIDCJJ_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 03:22:29
            Original ID  :: gnl|Prokka|ELOIDCJJ_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 247362
            Orig. end    :: 262246
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14884
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[257362:259761]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12399
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14884
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14884
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1108..2370)
                     /locus_tag="ctg2_276"
                     /transl_table=11
                     /translation="MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEI
                     VEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDD
                     VELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLI
                     QAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQ
                     GGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELL
                     SKVLPEDLLRFGLIPEFIGRLPVIASLEQLDETALVEILTKPKNALVKQYKKMLELDDV
                     ELEFEGEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVAD
                     GEAPRLVLKDGTVVGQDKTSA"
     CDS             complement(2642..3916)
                     /locus_tag="ctg2_277"
                     /transl_table=11
                     /translation="MSVKWEKQEGNEGVLTVEVDADTFKTALDDAFKKVVKQVSIPGFR
                     KGKVPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGESL
                     IFTAKVTVKPEVKLGDYKGLGIEKDDTAVTDEDVQNELKALQERQAELVVKEEGAVENG
                     DTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEEQLTGLEAGAEKDVEVTFPEE
                     YHAEELAGKPAVFKVKIHEIKAKELPELNDEFAKDIDEEVETLAELTEKTKKRLEEAKE
                     NEADAKLREELVLKASENAEADVPQAMIDTELDRMLKEFEQRLQMQGMNLELYTQFSGQ
                     DENALKEQMKEDAAKRVKSNLTLEAIAQAENLEVTDEEVEAELTKMAEAYNMPVENIKQ
                     AIGSTDAMKEDLKVRKAIDFLVENR"
     CDS             complement(4133..5137)
                     /locus_tag="ctg2_278"
                     /transl_table=11
                     /translation="MTHDKKKADIIPFPRLKERLVDKGMAAMKDKQYEEALELFSEAVS
                     HGDTESDVHLGMAICFLELGELEEAKQVCEKMLNEGYGHYFTVLQVYMTILIQLKQYEE
                     VKSTIEAVLEENQLPAESAEQFYRLLEFSRKMTDPDQQEEAWEEEYEDILDTEKVLNSP
                     AEQMNLIHSLKDRNISKYTGLLKTILQDPGAHPLIKTMILTLMAEHDYSKPVHITKFGD
                     SMTAIPSETVQPDAAPILHRVLRVLDETLGNENPTLYAAVEELWRRHLYVLHPFMPKFL
                     NADLWAAALHKVGYEMHGIDIEPEELHMMYEFDSRELEEACTMIKDIEEISYL"
     CDS             complement(5256..5855)
                     /locus_tag="ctg2_279"
                     /transl_table=11
                     /translation="MEPLKTHTGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFD
                     WRYLENGEPDPEFELNRKVYEGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPSFA
                     DIFHQNCFKNGMLPIRMPYDQWKKLAGQYENQSLNMTVDLENQLIHDSEGKEISFEVDP
                     HWKEMLINGYDEISLTLLLEDDIQQFESKRSSWLQA"
     CDS             complement(5871..7289)
                     /locus_tag="ctg2_280"
                     /transl_table=11
                     /translation="MMPRTIIEKIWDRHVVKSGEGKPDLLYIDLHLIHEVTSPQAFEGL
                     RQKGRKVRRPQNTFATMDHNIPTVNRFDIKDEVAKRQVTALERNCEEFGVRLADLHSAD
                     QGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRP
                     KTLEIRVDGTLQKGVTAKDVILSVIGKYGVKFGTGYVIEYTGEVFRNMSMDERMTVCNM
                     SIEAGARAGLIAPDDTTIEYCKNRKYAPKGEEFEKAAAEWKALKTDPGAVYDHSIVLDG
                     SEISPMVTWGVNPGMVLPVDAQIPAPETIDSEDGKKEAIRAYEYMGIAPNQKIEDIKVE
                     HVFIGSCTNSRMTDLRQAADMIKGRKVADSVRAIVVPGSQSVKQQAEEEGLHRVFLEAG
                     FEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGH
                     FVDVRKFYQEKTVV"
     CDS             complement(7340..8437)
                     /locus_tag="ctg2_281"
                     /transl_table=11
                     /translation="LKKRIALLPGDGIGPEVAESAADVLKSVAEQFGHEFEFENGLIGG
                     AAIDAHQNPLPEETVALCERSDAILLGAVGGPKWDQNPPELRPEKGLLGIRKKLGLFAN
                     LRPVTVFESLSEASPLKKEYISGVDFVIVRELTGGLYFGEPSRQYVNEAGEKEAVDTLF
                     YKKEEIARVVREAFKMAAGRKGKVTSVDKANVLSSSRLWRETADEIAKEFPDVTLEHML
                     VDNAAMQLIYAPSQFDVIVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLFEPVH
                     GSAPDIAGKGMANPFAAILSAAMLLRTSFGLENEAQAVEKAVAKVLADGSRTRDIARDG
                     QYAGTHDITEKVKAALAGSNTKSIV"
     CDS             complement(8458..10014)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_282"
                     /sec_met_domain="HMGL-like (E-value: 2.8e-97, bitscore:
                     319.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRKINVFDTTLRDGEQSPGVNLNSREKLAIAKQLERLGVDIIEAG
                     FPASSRGDFLAVQEIARTIKNCSVTGLARSVKGDIDAAWEALKDGVSPRIHIFIATSDI
                     HLKHKLKMTREEVKEKAVEMVKYAKERFPIVQWSAEDACRTELPFLAEIVEKVIDAGAS
                     VINLPDTVGYLTPAEYGNIFKYMKEHVPDISRVKLSAHCHDDLGMAVANSLSAIENGAD
                     QIECAINGIGERAGNAALEEIAVALHVRNDAHQADSSLNLHELKRTSDLVSKLTGMAVP
                     RNKAIVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRL
                     NALGFQFDSEEINKFFTMFKELTEKKKEITDDDLISLILEEKVTDKKIGYEFLSLQVHY
                     GTSQVPTATVSLKNQENEQLIQEAATGAGSVEAVYNTLGRCIDKNIELTDYRIQSNRKG
                     EDALAQVYVRVTVNGKETSGRGIAQDVLEASAKAYLNAVNRQLVLDCNLDGLKRRTAVG
                     S"
     CDS             complement(10001..11029)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_283"
                     /sec_met_domain="IlvN (E-value: 3.4e-78, bitscore: 255.1,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.9e-68, bitscore: 221.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIKENVLAGKKVAIIGYGSQGHAHALNLKESGIDVIV
                     GVRQGKSFTQAQEDGHKVFSVREAAAQADIIMVLLPDEQQQKVYEAEIKDELTAGKSLV
                     FAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVSGEAKDT
                     ALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLTALVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKQVLTDI
                     QNGTFAKEWIVENQVNRPRFNAINASENEHQIEKVGRQLREMMPFVKQGKKKEAVVSVA
                     QN"
     CDS             complement(11052..11570)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_284"
                     /sec_met_domain="ALS_ss_C (E-value: 8.6e-31, bitscore:
                     100.2, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETSGVSR
                     ITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSARTEING
                     IIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKA
                     SSNKTISIV"
     CDS             complement(11614..12399)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_285"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.4e-46, bitscore:
                     150.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTGNLKHFAKSAKVAHIDIDPAEIGKIIETQIPVVGDSKIVLQEL
                     LKQNGKQGQTEEWKQQLSEWKEEYPLWYTDDREEGLKPQKLIEYIHQFTNGEAIVATDV
                     GQHQMWAAQFYPFRKADKWVTSGGLGTMGFGLPAAIGAQLADRNATVVAILGDGGFQMT
                     LQELDVIRQLNLPVKVVILNNECLGMVRQWQEIFYEERYSESKFSAQPDFVKLSEATAL
                     KASGFHRKKRRKKSLKRRFHQKNRPLLTSGSPKARKYSR"
     CDS             complement(12430..13290)
                     /locus_tag="ctg2_286"
                     /transl_table=11
                     /translation="MGTNVQADSLSADCTKTMNGALMLIESLKKENVEMIFGYPGGAVL
                     PIYDKLYQSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADILGITMPITKHSYQVRRPEDLPRVIKEAFHIAT
                     TGRPGPVLIDIPKDVAAFEGEFRYDHEISLPGYQPVKEPNYLQIRKLVEAVSSAKKPVI
                     LAGAGVLHGKASEDLKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMAL
                     YHCDF"
     CDS             complement(13966..14106)
                     /locus_tag="ctg2_287"
                     /transl_table=11
                     /translation="MPDNILFMTSLISYEIRTVYAYVCIKSLFNRTEYLTSMPEGQRKI
                     A"
     CDS             complement(14474..14659)
                     /locus_tag="ctg2_288"
                     /transl_table=11
                     /translation="LKYAFAYKNHNIETIFCGKDELFEELKQFLITQCGLIIVEVSRAD
                     YYTEQEMNQWNDRYTL"
     CDS             complement(14796..14882)
                     /locus_tag="ctg2_289"
                     /transl_table=11
                     /translation="GLEVFLYFILVVRNKSPVFDENCKVILM"
ORIGIN
        1 ctcagtcacc gccatgccgg cggcgatctg gatcatattg acggcttcac gtccgtttct
       61 cgtatatgcg gtcagcacgc tgagagcttc gtcagaaatc tctttctgaa ttttgtcggc
      121 tgcttttttc gcaacgattt taagttcatc cttttccagc tcgcggaaaa atacttcaag
      181 acagcgcgaa cggatggccg gaggaatttc agtcggcatt ctcgttgtcg caccgatcaa
      241 acggaaatcc gccggaagcc cattttgaaa aatatcatgg atatgattcg gtatttgcgt
      301 attttcttca ctgtaatacg cactgtctaa aaatactttt cggtcttcaa gcaccttcag
      361 cattttattc atctgaatcg ggtgaagctc gccgatttca tcaataaaca ataccccgcc
      421 gtgagcatgg gtcacagccc cctgtttcgg ctgcggaatg cctgcttggc ccatcgcacc
      481 cgctccctga taaatcggat catgcactga accgataagc ggatcggcaa tcccccgttc
      541 atcaaatcgc gcggtcgtcg catcaagttc aacaaaaaca gcctgctttt gaaacggtga
      601 ctgtttatgt tttttcgctt cttccaatac cagccgcgcc gcagccgttt taccgactcc
      661 cggaggaccg taaataatga cgtgctgcgg gttcggtccg caaagcgctg cttttaatgc
      721 tttaattccg tcttcctggc cgacaatgtc ctgaaagctt ttcggccgca ccttttctga
      781 taaaggttct gataaactga tggcgcgcat tttgcgcagc tgttccattt ccttttttga
      841 ttctttatct atcgtcactt tttgtgttcg ctggtttttg agcagattcc aaaaatatag
      901 tccgatgact atcccgaaaa acagctgtac aaataatgcg atccctgtcc aactcatgct
      961 ggtccctcct gaaaaaacga tttatgtatc caattcattc ctctgtccgc tagtatctcc
     1021 cagcaaagcc cggagtaaac attttcagaa gggtcaagac aagaaaaaaa acctcctgat
     1081 taattcgggt caggaggttt tgtcgtgtta tgctgatgtt ttatcttggc cgacaacagt
     1141 gccgtctttt aatacaagac gcggcgcttc accgtctgcg actgtcgctc cggtgatgac
     1201 acatttttca atatcatcgc gggacggcag atcaaacatg acgtcaagca tgatgccttc
     1261 aatgatagaa cgcaggccgc gtgcgcctgt tttacgctcg atcgcttttt tcgcaatttc
     1321 agataatgcc tcgccttcaa attcaagctc gacatcatca agttctaaca ttttcttgta
     1381 ttgtttgacg agtgcgtttt tcggtttagt cagaatttca accagtgccg tttcgtcaag
     1441 ctgctcaagg cttgcaatga caggaagacg gccgatgaat tcaggaatca gaccgaaacg
     1501 gagcaggtct tccggaagaa ctttagaaag cagttcttct ttttccaggt ctgccgcttt
     1561 attatcagag ccgaagccga tgactttttg tccgagacgg cgtttgatga tttgttcgat
     1621 gccgtcaaat gcaccgccgc aaatgaacag aatgttcgtc gtatcgatct ggatgaattc
     1681 ctgatgagga tgtttgcgtc ctccttgagg cggcacgctt gcaaccgttc cttcaagaat
     1741 tttcagcagc gcctgctgaa cgccttcgcc tgatacatcg cgtgtaatgg acgggttttc
     1801 agattttcgc gctactttat cgatttcatc gatatagata atgccttttt ctgctttttc
     1861 cacatcatag tctgctgcct gaatcagctt gaggaggatg ttttctacgt cctcaccgac
     1921 atatccggct tcagtcagag atgtagcgtc cgcgatcgca aacggaacgt tcagaatacg
     1981 cgcaagcgtc tgggcaagaa gtgttttccc gcttccagtc ggtccgatta aagaaatatt
     2041 acttttagaa agctcaacat catccacttt actgttggaa ttgatgcgtt tgtaatggtt
     2101 gtataccgca accgcaagtg atttcttcgc ctgatcctgt ccgatgacat attcattcag
     2161 aatctcacgg atttcctgcg gcttcggaac gtctttaaat tcgacttctt cttccgtacc
     2221 aagctcttcc tctacgattt ctgtacagag ctcaatacat tcgtcgcata tatatacacc
     2281 cggtcctgca accagcttac gaacctgatc ttgcgttttt ccgcagaacg agcatttcaa
     2341 ttgtcctttt tcctcgttga atttaaacat tctttcaccc cttaatcttg tctcactttt
     2401 tcttttacct gaagggcaaa agaaaacggt tcttgctacg atcgagtatg tattgcattt
     2461 taccatactt tccagtaaga cggtaacaat gtgtttcgca cttgcacatt ctatatgtat
     2521 gacgaaaaac agcccggcaa tgactatctt gccccaagaa aaagagttat atcataattg
     2581 tacaaaacaa ggcacgaatt aatcgcgccc tgttttatta tgtctattat tatgaaccat
     2641 attaacggtt ttctacaaga aaatcaattg cttttcgaac ttttaaatct tctttcatcg
     2701 cgtcagttga accgattgcc tgcttgatgt tttcaaccgg catgttgtaa gcttcagcca
     2761 ttttagtcag ctctgcttca acttcttcgt ccgttacttc aaggttttct gcttgagcga
     2821 tcgcttcaag agtcaggttt gattttacgc gttttgcggc atcttctttc atttgctctt
     2881 ttaacgcgtt ttcgtcttgg cctgagaatt gagtgtaaag ctcaaggttc atgccttgca
     2941 tttgcagacg ctgttcgaat tctttcagca tgcggtcaag ctcagtgtcg atcatcgctt
     3001 gaggaacatc agcttcagcg ttttcagatg ctttcagaac aagctcttca cgcaatttag
     3061 cgtcagcttc gttttctttt gcttcttcaa ggcgtttttt tgttttctca gttaattcag
     3121 caagcgtttc aacttcttcg tcaatgtctt ttgcgaattc gtcgttaagc tcaggaagct
     3181 ctttcgcttt gatttcatga attttcactt tgaaaacagc tggttttccg gcaagctctt
     3241 cagcgtggta ctcttcaggg aatgttactt caacatcctt ttcagcgcct gcttcaaggc
     3301 ctgttaactg ctcttcgaag cccgggatga atgaacctga tcctacttca agtgagtagt
     3361 tctcagcttt tccgccttca aacgcttcgc cgtcaacgaa accttcgaag tcaagaacga
     3421 ctgtatcgcc gttttcaaca gcgccttctt ctttcacgac aagctcagcc tgacgctctt
     3481 gaagcgcttt aagttcgttt tgtacatctt cgtcagtaac ggcagtgtca tctttttcga
     3541 ttcctaagcc tttgtaatcg ccaagtttca cttccggttt tacagtcact tttgcagtga
     3601 aaattaagct ttcgcctttt tcgatttttt caacatcgat ttcagggcgg tctacaggct
     3661 caatgccggc ttcttcaacc gctttagggt attctacagg aagtaaaata tctaaagcat
     3721 cctggtaaag agcttcaacg ccgaaacgct gttcgaataa accgcgggga actttccctt
     3781 tgcggaatcc aggaatagaa acctgtttta ctactttttt aaatgcatca tcaagagctg
     3841 ttttgaacgt atccgcatca acttcaaccg ttaatacgcc ttcgttgcct tcttgttttt
     3901 cccattttac agacatgtgt ttccctccaa aaatctattc aggttgtgtc ggtcttccat
     3961 tctaaagcaa tccgcggctt tgtcaaagaa aaaaccgctt tgaatcagaa tcattatgta
     4021 atgaactggc agcctgtcca accgtaattc tcatttcagt taaaccgcta tacataaata
     4081 caaccactat attataacat aacgcctact gctttcaact atatggtgtg atttacaaat
     4141 aagaaatttc ttcaatatcc ttaatcatcg tgcaggcttc ttcgagttcg cggctgtcaa
     4201 actcgtacat catatgaagt tcctccggct caatgtcaat gccgtgcatc tcgtaaccga
     4261 ccttatgaag cgccgccgcc cataaatccg cgttcaaaaa cttcggcata aaagggtgca
     4321 ggacgtacag atgtcttctc cacagctcct cgacggcagc atataatgta gggttttcat
     4381 tgcccagcgt ttcatcaagc acccggagaa cgcgatgcaa aatcggagcc gcatcaggct
     4441 ggaccgtttc actcggtatc gcggtcattg aatcgccgaa ttttgtaata tggaccggtt
     4501 tactgtagtc gtgctcggcc atcagcgtca aaatcattgt cttaataaga ggatgcgcgc
     4561 ccggatcttg aagaatcgtt tttaagagac ccgtgtattt tgaaatattg cggtctttaa
     4621 gagaatgaat cagattcatt tgttcagcgg ggctgttcag cactttttcc gtatcaagaa
     4681 tgtcctcgta ttcctcctcc cacgcctcct cctgctgatc gggatcggtc attttgcggc
     4741 tgaattcgag cagccggtag aattgctccg cactttctgc gggcagctgg ttttcttcca
     4801 gcacagcttc aattgtgctt ttgacttctt catattgttt cagctgaatt aaaatggtca
     4861 tgtacacctg caatacggtg aaataatggc cgtacccttc attcagcatt ttctcgcaaa
     4921 cttgttttgc ttcttccaat tccccgagtt ccagaaaaca aatcgccatg cctaaatgta
     4981 cgtcggactc ggtatcgccg tggcttaccg cctctgaaaa cagttcgagg gcctcctcat
     5041 actgtttatc cttcatggcg gccatccctt tatcaaccaa gcgttctttc agacggggga
     5101 aaggaatgat atcagctttt ttcttgtcat gcgtcatact ttatttcctt tcaggcgctt
     5161 attttgttca agtgtatcaa cacgcgtcat gaaacacaag aaaggatgat gcacacggta
     5221 aaaaaagccg ccggacagat gccgggcggc ttttttcagg cttgaagcca tgaacttctt
     5281 ttcgattcaa actgctgaat gtcgtcctcc agcagaagcg ttaatgaaat ttcatcataa
     5341 ccgttaatca gcatttcctt ccagtgcgga tcgacttcaa atgaaatctc ttttccttca
     5401 ctgtcgtgaa tgagctggtt ttccaaatca accgtcatat ttagagactg attttcatat
     5461 tgaccggcga gttttttcca ctgatcatac ggcatacgga tgggaagcat accgttttta
     5521 aaacagttct gatgaaaaat atcggcaaat gacggagcaa tgatgatttt gaagccgtaa
     5581 tcatccagcg cccaaggagc gtgctcacgg gatgatccgc agccgaaatt ctctccggca
     5641 attaatatgg acgcgccttc atagactttg cggtttaatt caaattcagg atcaggctca
     5701 ccgttctcaa ggtatctcca atcaaaaaac gcgaatctgc cgtatccggt tctttcaatt
     5761 cttttcaaaa actgtttcgg aataatctgg tccgtatcga cgttgatccg gtttaagacg
     5821 gccgcttttc ccgtatgcgt ttttaaaggt tccatctttt cgcgcactcc ttacacaact
     5881 gttttttctt gataaaactt tcttacatcg acgaaatgcc cgtgaatggc cgccattgcc
     5941 gccatcgccg gactgacaag gtgtgttctc gcgccttttc cctgtctgcc ttcgaagttg
     6001 cggttggaag tggaagcgca tcgttcccct tcaggcacga catcattgtt catactgagg
     6061 cacatgctgc agcctgattc cctccattca aagccggcct cgagaaacac gcggtgcagc
     6121 ccttcttctt cggcctgctg tttcacgctt tgagaacccg gcaccacaat ggctctgacg
     6181 ctgtcggcga cttttcggcc tttgatcata tccgcagcct ggcgaagatc ggtcatccgt
     6241 gaatttgtac aggagccgat aaacacatgc tctactttaa tatcttcaat tttttgattc
     6301 ggcgcgatcc ccatgtattc gtaagcgcgg atggcttctt ttttaccgtc ttcagaatca
     6361 atcgtttccg gcgcaggtat ttgggcatcg accggaagaa ccatgccggg attgacaccc
     6421 catgttacca ttggagaaat ctcgctgccg tctaacacga tggaatgatc gtatacggcg
     6481 cccggatcgg tttttaacgc tttccattct gcggcggctt tttcaaattc ctcgcctttt
     6541 ggcgcgtatt tacggttttt acagtattca atcgtcgtgt catcaggagc gatcagtccc
     6601 gcacgggctc ccgcttctat tgacatattg cagacagtca tgcgttcgtc catagacatg
     6661 tttctgaata cttccccggt gtattcaatg acatatccgg taccgaattt caccccgtat
     6721 tttccgatga ccgacaagat gacatccttc gctgtcactc ctttttggag cgttccgtca
     6781 acgcggattt caagcgtttt cggccgctgc tgccataatg tctgtgtgga aagaacatgt
     6841 tccacctcac ttgtgccgat accgaaggca agcgctccga acgcgccgtg agtcgatgta
     6901 tggctgtctc cgcaaacgat cgtttttccc ggaagtgtca gaccaagctc aggcccgacc
     6961 acgtgaacga ttccctggtc tgcgctgtga agatccgcaa gacggacgcc gaactcctcg
     7021 caatttcgtt caagcgcggt tacttggcgc tttgcgactt catctttaat gtcaaaacgg
     7081 ttgacggtcg gaatattgtg gtccatcgtc gcgaatgtgt tctgcggccg tctgaccttt
     7141 cttcccttct gccttaaccc ttcaaacgcc tgaggagacg tcacctcatg aatgaggtgc
     7201 agatcaatat agagaaggtc gggttttcct tcaccgcttt ttacaacatg ccgatcccaa
     7261 atcttttcga tgattgttcg aggcatcatc tttgtttcct ccctctacct attgaactaa
     7321 gaccgctttc tttaaagcgt catactatag attttgtatt cgagccggct aatgcggctt
     7381 ttactttttc agtaatgtca tgcgttccgg catattggcc gtcccgggcg atatcacgtg
     7441 tacggctgcc gtctgcaagc acctttgcga ccgccttttc caccgcctgc gcttcgtttt
     7501 caagtccgaa agatgttctc aaaagcatcg ccgctgataa aatcgccgca aacggattgg
     7561 ccatcccttt accggcgatg tcaggcgcag atccatgcac gggttcaaac aagtgaagac
     7621 ctgaacttga taaactggct gacggcagca tgccgagcga gcctgtcagc atggaggctt
     7681 catcgcttaa aatatcgccg aacatatttt cagttacgat gacgtcaaac tggctcggag
     7741 cgtagatgag ctgcatcgcg gcattatcga caagcatatg ttcaagcgtc acatcaggaa
     7801 attcttttgc gatttcatct gccgtttcac gccacagtct gcttgaagaa agcacattcg
     7861 ccttatcaac ggacgtcact tttccttttc tgccggcagc catcttaaag gcttctctga
     7921 caacgcgtgc gatttcttct ttcttataaa aaagggtatc gaccgcttcc ttttctcccg
     7981 cttcattgac atactgtctg ctcggttctc cgaagtagag gccgcccgtc agttccctga
     8041 cgattacaaa gtcgacgccg ctgatatatt cttttttcag cggagacgcc tcagacaggc
     8101 tttcaaatac ggtcacagga cgcagattgg caaacaggcc gagctttttt ctgatgccga
     8161 gcaggccttt ttccggtctg agctccggag ggttttggtc ccatttcggt ccgccgactg
     8221 ccccgagcag gatggcgtcg gatctttcac aaagagccac cgtctcctca ggaagggggt
     8281 tttgatgggc gtcaatcgct gctcccccga tcagcccgtt ttcaaattca aattcatgtc
     8341 cgaattgttc agcaacgctt ttcaatacat ctgccgctga ttccgccact tccggtccga
     8401 ttccgtcacc tggaagcaaa gcaatgcgtt ttttcaaatc aaacgttctc ctttctatta
     8461 cgagccgacc gcagtccgtc tctttaatcc gtctaaattg caatccagca ccaactgccg
     8521 gttcacggcg ttcagataag ctttagcaga agcttccaga acatcctgcg cgattccccg
     8581 ccctgatgtt tcttttccgt tcacggtcac tctgacataa acttgagcca gcgcgtcttc
     8641 gcctttccgg ttggattgga tgcggtagtc tgtcagttca atatttttat cgatgcagcg
     8701 cccgagcgta ttataaacgg cttctacgct gcccgccccc gttgccgcct cttgaatcag
     8761 ctgttcgttt tcctgatttt tcaaagagac tgttgcagtc ggcacctgag acgttccgta
     8821 atgcacttgc agagacagaa attcatagcc gatttttttg tccgtcactt tttcttctaa
     8881 aataagagaa atcaagtcat catcggtgat ttcttttttc ttttcggtca gttctttaaa
     8941 catcgtaaaa aatttattga tttcctcact atcaaactgg aatccaagcg cattcaggcg
     9001 gtctttgaac gcatggcgtc cggaatgctt tccgagtacg agcgcatcag cagtcacgcc
     9061 gacaagttcc ggtgaaatga tttcatatgt tgatttttct ttcaggaaac cgtcttggtg
     9121 aatgccggat tcatgtgcga aagcgttatc tccgacgatt gctttgttgc ggggaacggc
     9181 catgcccgtc agtttgctga caagatcact cgtccgcttc aattcatgaa gattgagaga
     9241 tgaatcggct tgatgcgcgt catttctgac atgaagcgca acggcgattt cctctagcgc
     9301 ggcgttcccg gctctttctc ctatgccgtt aatggcgcat tcaatttgat cagcgccgtt
     9361 ctcaattgcc gaaagtgagt tggcaaccgc cattccgaga tcatcgtggc aatgggcaga
     9421 gagctttacc cggctgatat ccggaacgtg ttccttcata tatttaaaga tgtttccgta
     9481 ttcagcaggc gtcaggtaac ctacagtgtc cggcaggttg atgacgctcg cgccggcatc
     9541 aatcactttt tctacgattt cagccagaaa cggaagttcg gtgcggcatg cgtcttctgc
     9601 cgaccattga acgatcggaa agcgttcttt tgcatacttc accatttcaa ccgctttttc
     9661 cttaacctct tcccgcgtca ttttcagctt atgcttcaga tgaatgtcag aggtggcgat
     9721 aaagatgtga atgcgcgggc tgaccccgtc tttcagcgct tcccaggctg cgtcaatgtc
     9781 acctttgaca gatcgggcaa gccctgttac cgaacaattt ttaatcgttc ttgcgatttc
     9841 ctgcacggct aaaaaatcac ctcgggatga agcgggaaat cccgcttcaa taatgtccac
     9901 cccgagtctt tcaagctgct tggctatcgc cagtttctcc cgggaattga ggttgacccc
     9961 gggagattgt tcaccgtcac gaagggtcgt gtcgaaaaca ttaattttgc gcaacggaga
    10021 ccaccgcttc cttctttttg ccttgtttga caaacggcat catttcacga agctgtctgc
    10081 cgaccttttc aatctgatgc tcgttttcgc ttgcattgat cgcattgaaa cgaggacggt
    10141 tcacttggtt ttccacgatc cattcttttg cgaatgtacc gttttgaata tccgttaata
    10201 cttgtttcat cgattctttt accttcgcat cgactacgcg cggtcctgat acaaagtctc
    10261 cccattgagc cgtatcggaa atagagtatc tcatgcccgc caatccttct tcatacatca
    10321 agtctacgat cagcttcagt tcgtgcagac actcgaagta tgcgagttca ggctggtagc
    10381 cggcttctgt cagcgtttca aaacccgctt tgacaagcgc cgttaaacct ccgcacagaa
    10441 cagcctgctc accgaacaaa tccgtttccg tttcttcctt aaatgttgtt tcaagaaccc
    10501 ccgcacgcgc tccgccgatt ccttttgcat aagcaagagc cgtatctttc gcttcgcctg
    10561 atacatcctg gtagatggca aacaatgccg gtacgcccgc gccttgttca tatgttcttc
    10621 tgacaaggtg tccaggtcct ttaggggcga caaggaatac atccacatca gcaggaggca
    10681 cgatctgatg gaaatggacg ttaaatccgt gtgcgaatac caatgacttg cccgccgtca
    10741 attcatcttt gatttcagct tcatatactt tttgctgctg ctcatccgga agaagaacca
    10801 taatgatatc agcctgggca gccgcttctc ttaccgaaaa gactttatga ccgtcttctt
    10861 gggcctgtgt aaatgattta ccttgtctga cgccgacaat gacatcaatt ccgctttctt
    10921 ttaagttcag cgcgtgtgca tgaccttgtg aaccgtaacc gataatcgct acttttttac
    10981 ctgccaatac gttctctttg atatcaccgt tataatatac ttttaccatt ttaatctctc
    11041 ccttttttgt gttatacaat tgaaattgtt ttattggatg acgccttctg ctgggttccc
    11101 ctcgcaaaag ccgttgtgcc cgttctcgcg atttctttaa ttccgtaagg tttgagaagc
    11161 tctatgagcg cttcgatttt attagattcg ccggtaacct gaacgacgat gctgtctctt
    11221 gagacatcaa cgacggaagc tctgaacggc tcaatgattc cattgatttc cgttctggcc
    11281 gacggtgcgg aaacaacttt gattaatgcc agctcacgct gtacaatcga ttgatttgta
    11341 atatccgtca ctttcaggac gtcaatttgt ttgttaagct gctttgtcag ctgctctacg
    11401 tcattttcgc cttccacatg gacgacaaat gtaatccttg aaacaccgct tgtttcggtg
    11461 tggcctacag tgatgctttc gatattatag tgtcttttgg taaacaggcc ggtgatccgg
    11521 tttaataccc ccgagcggtt gaccaccgtt aatgtgataa tgcgtttcaa ggtttcaccc
    11581 ccaccatttc atgaagtcct ttacccggcg caatcatcgg gaatactttc tcgcttttgg
    11641 cgacccggac gtcaataacg gccggttctt ttgatgaaag cgccttttta agctcttctt
    11701 ccgcctcttc ttccgatgaa atccggacgc ctttaatgcc gtagcttctg acaatttgac
    11761 aaagtcaggc tgcgccgaga atttggattc agaatagcgt tcttcataga agatttcctg
    11821 ccactgtctg accatgccca gacattcgtt gttcaagata accactttga caggaaggtt
    11881 cagctgccgg atgacatcta attcctgaag ggtcatctga aaaccgccgt ctccgaggat
    11941 ggcaacgacc gtggcgttac gatcggccag ctgcgctccg atggccgccg gaaggccgaa
    12001 gcccattgtg ccgagccccc ccgaggtcac ccacttatca gcctttcgga aaggataaaa
    12061 ctgagccgcc cacatctggt gctggccgac atccgtcgcc acaatcgcct caccgtttgt
    12121 gaattggtga atatactcaa tcagcttttg gggtttcaag ccctcttctc tgtcgtctgt
    12181 ataccaaagc ggatactctt ctttccattc tgaaagctgc tgtttccatt cctctgtctg
    12241 tccctgtttt ccgttttgct tcaataattc ctgaaggacg attttactgt cgccgaccac
    12301 cggaatctgc gtttcaataa tttttccgat ttcagcagga tcaatatcga tatgcgctac
    12361 tttggccgat tttgcaaaat gcttcagatt tccggtcacg cgatcatcga accgcgctcc
    12421 gaatgctgat cagaagtcac agtggtaaag cgccatattc gctgtgtatg tgccgtgcat
    12481 ccccgccatt cccagaaaaa gaggatggtc tgccgggaaa ccgcccagac cgagaagcgt
    12541 gtgcgctacc ggaatttgct gctgttcggc ataatttttt aaatcttctg aagctttacc
    12601 gtgcaaaaca cccgctccgg ctaaaataac cggctttttc gcactgctga cagcttccac
    12661 gagctttcgg atctgcagat agttaggctc ttttaccggc tgataacccg gaaggctgat
    12721 ctcgtgatca tatctgaatt ctccttcaaa tgctgcgaca tccttcggta tatcaattaa
    12781 taccgggccc ggtcttcccg tcgtggcgat atggaacgcc tctttaatca cacgggggag
    12841 atcttccgga cggcggactt ggtagctgtg tttcgtaatc ggcatcgtaa ttcctaaaat
    12901 gtcggcttcc tggaaagcgt cgctgccgat gaccgaagtg gcgacctgac cggtaaacac
    12961 tacgagcggc agtgaatcaa tcatcgcatc cgcaagaccg gtaactaaat ttgtcgctcc
    13021 gggtccggag gtagcaatca caacccccgg ctttccggag actctcgcat acccttctgc
    13081 cgcatgaatc gcgccttgct cgtggcgggg caggatgtga accaatcctg attgataaag
    13141 tttatcgtaa atcggaagga cggctccccc cggatagccg aagatcatct cgacattttc
    13201 tttctttaat gattcaatca gcatcagagc cccgttcatt gtttttgtac aatcggcaga
    13261 caaagaatcc gcctgtacat ttgtgcccat tttcagttcc tccttttcaa tgttcccttc
    13321 taaaatccaa ttcataaaac gcagcgccgg ctgacgcaaa taaaaaagcc ttcccaccca
    13381 cattcagcca agcatttcat gcgatagcca aaaggggcga aaaggctttg ctctccgcgg
    13441 taccaccctt gtttacggtc atatgcagac cgtctcatgg ataatgatta tccgttttga
    13501 taacgagtaa acattgcgtt cactcggccg agtcctactc tttacatttc agaccggcac
    13561 tctgagggga gttcactttg atttgtttta ccggctctca gcgttaccgg ctctctgtga
    13621 aaaacttcag caaagctact tatcctcttc tgcgcttttt attatggcag ctcttttatt
    13681 aaaaaagaac cttcatttgt ttgttttttc agtgttttat gatttttctt tttagcgtga
    13741 atcatttatt tatttttgtt tgaactcata ttacgcccgt ttgcagacag tgtcaacagc
    13801 atttttataa ttattagaca atttagatta atcaatctat tttgtatacg ctttcattac
    13861 tgatataaaa ggatcggcaa atgttaaaag tttttatatt ttttttatta atctctcaag
    13921 attacatgaa atttttccgt tcatatacga atatgtcaca ttttattacg cgatttttct
    13981 ctgtccttcc ggcatgcttg tcagatattc cgttcgattg aacaggctct ttatacagac
    14041 atacgcatac actgttctta tctcgtaaga aatgagtgat gtcatgaata agatgttatc
    14101 aggcatgcag ggcctgcctc ctggatttcc gcctttaccg gtcttaccgc cgcagtctta
    14161 ctatcctccg gccccgatgc atacagcacc atatcaaggc ggcccttctt ttcagcaggg
    14221 atttccgcca tccggatacg gacagcagac cccgcaaagc acactgtcat tcgccggaca
    14281 gcaattcgtt ccgtaccctt atacatccgg gtactacggc caaaccttca gtgacgtcgg
    14341 cggaagcctc ggcgccgggg cacatcccgg cgcgctcggg ggcggtttca gcggccatgc
    14401 cgggggcttc agcgctccga gcggattcag atgatacaaa aaccggtctc acacggccgg
    14461 tttcttttct tattcacaga gtataacggt cattccactg attcatttcc tgctccgtat
    14521 agtaatcagc ccttgaaacc tcaacaatga ttaaaccgca ttgagtgatt aaaaattgtt
    14581 tcagttcctc aaacagctcg tcttttccgc aaaagatcgt ttctatattg tgatttttat
    14641 atgcaaatgc gtacttcaaa agctaattcc tcctgctgtc tttctatcaa tcatcaacaa
    14701 aacgtatgat agaaatcaga taatttatca ctcaagggcg ccttaagtat ctttatacat
    14761 atatttatta cggtaaatat tacattaagt ttcatttaca ttaaaattac tttacaattt
    14821 tcatcaaata cgggactttt gtttcgtaca actaaaataa aatacaaaaa aacctcaagc
    14881 ccat
//
