LOCUS       c00065_gnlPro..        10649 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KGFGMFNE_68.
ACCESSION   c00065_gnlPro..
VERSION     c00065_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 17:45:19
            Original ID  :: gnl|Prokka|KGFGMFNE_68
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10649
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10649
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1326:5883]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1327..5883
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..10649
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10649
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             153..1151
                     /locus_tag="ctg65_1"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNTFHSKELFLIYEATPGYTPLLIVA
                     TEDGRPVARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEVFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRM
                     RQIKKGLKNGARVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNDMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSGDDAYLWFSGGMRKTYALQYPGVLAVWKALEDAHQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRVNWSWLNKLLVKFYV"
     CDS             1327..1731
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_2"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.6e-24, bitscore:
                     75.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAEGKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             1760..3313
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_3"
                     /sec_met_domain="CT_Btheta (E-value: 1.6e-290, bitscore:
                     952.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             3345..4265
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_4"
                     /sec_met_domain="OAD_gamma (E-value: 5.5e-16, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQNNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWIGLFDSGRKLLDQIVVPAGVLGPNQSYARVSDGAAEW
                     EVKGGSGDKYVTPSTNNKTLDSNAKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             4290..4721
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.3e-22, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPA
                     AKPVTVRPMPNAPTAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             4723..5883
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_6"
                     /sec_met_domain="OAD_beta (E-value: 2.2e-153, bitscore:
                     499.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLGFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             6178..7518
                     /locus_tag="ctg65_7"
                     /transl_table=11
                     /translation="MKRIIILFFLCCTIPLIAQHTDPIQEAMANYDYETALSLIAQKKT
                     TPPLLLQKGKALRGLGLTTEALATYQEIICNDTTNTRAFIEAAECCRALAKYNQALKYY
                     EHALDLNPENKYVRIQYISLLLSQQKFSEALGESSLMTEKDSSAIVLHLQAQSFEGMGE
                     LLPAAGCYYNIQAKYPDDYLAASKLGALNISGSYFDEAIEATEKYRQIDSTNISVNRQN
                     ALAYCLKQDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAAEKYYEAHDFLEVARKYDP
                     NNINLLYYLGRACSKTSWKKEGVDYLEKAIDLSIPKDSSMTRLYIGMTDCYKMAQMYKE
                     QIASIKERYQRYDKQNHKLLYDMAYIYFYDLKDKKNAERYLEAFLKTRPKDTKEEAEMN
                     ERGELVLGKSNYYNAAANWLKDIQSKQKIEDFFQNSSPQLPLPKKDK"
     CDS             complement(7603..8607)
                     /locus_tag="ctg65_8"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAQ"
     CDS             9030..9284
                     /locus_tag="ctg65_9"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             complement(9365..10579)
                     /locus_tag="ctg65_10"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIYLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRISRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
ORIGIN
        1 atacgtactc acttttcata ccatatttct cctataaaat atattttctc cattaaatac
       61 gcaactatat attatacttt acttcaagca gctccaacaa attctttatt ttgttgttga
      121 ataaagaata aaaagtgtaa atttgtacct agatgccact gaaactaaca acatattatc
      181 atgggaagga tattcctgaa ttgccgggaa aaaatacctt ccattccaaa gagttatttc
      241 tgatttatga agcaactcct gggtatactc ctttattaat agtggcaaca gaagacggca
      301 gaccggtggc acgcctgctt gctgccatcc gcaaagcaaa gaagtggctc ccttcttctt
      361 tagtgaaaca ttgtgtagta tatagtgaag gcgaatttct ggacgagtct ctttcgacca
      421 acaaagaaaa ggcagaagaa gtcttcggcg atatgctcga acatctcaca caagaagcat
      481 cgcgcagctg tgtcctgatc gaattccgga acctgaacaa ttcgatgttc ggctatcggg
      541 ttttccgtgc caatgattat ttccctgtca attggttgcg ggtacgcaat tcgctgcaca
      601 gtatgaaaaa gacggaagac cggttcagtc cgtcgcgtat gcgtcagata aaaaaaggac
      661 tcaagaatgg agccagagta gaggaagcac ataccgtgga agagatacac gatttctcac
      721 ggatgctgca caaggtttat tcctcccgca tacgcagata tttccctgcc aacgactttt
      781 tccgccacat gaacgatatg ttaatcaaag gacaacaggc aaaaatattc gttgtgaaat
      841 acaaagagaa aatcattggc ggttctgtct gtatctattc gggagacgac gcataccttt
      901 ggttttcggg aggaatgaga aagacatacg cacttcaata tccgggtgtg ctagctgttt
      961 ggaaagcatt ggaagacgca caccaacggg gattccgcca catggaattt atggatgtag
     1021 gacttccgtt ccgtaaacac ggttatcgtg atttcgttct tcgcttcgga ggaaaacaaa
     1081 gcagtacccg ccgttggttc cgcgtcaatt ggagttggct gaataaactc ttagtcaagt
     1141 tttatgtcta aatgtaatct caagattaca aaacaatgtt ttatgctcct ttcccaccat
     1201 tttttctgtt taataatcca ataattaaat gcagaaatat ttctttatta gataagaaat
     1261 gtctttcttt gtgctgtttt atgccttata agcacagatt taaaaccaaa taaaaaaagt
     1321 atagttatga agatttcaca cattgaacat ctgggcattg ctgtaaaaag catcgaagaa
     1381 gcccttcctt actacgaaaa tgtattaggt ctgaagtgtt acaacattga aacagtggaa
     1441 gatcagaaag taagaactgc ttttttaaaa gtgggcgaaa caaaaattga actgttggag
     1501 cctacttgcc cggagagtac tattgccaaa ttcattgaaa acaaaggtgc aggcgttcac
     1561 cacgtcgcat ttgctgtaga agatggcgta gccaatgcgc tggcagaggc agaaggcaaa
     1621 gaaatccgcc ttatcgacaa agctccccgc aaaggtgctg aaggtttgaa tatcgctttc
     1681 cttcacccga aatcaacttt gggtgtgtta acagaactct gcgaacatta atcataaact
     1741 ctaaaaccaa caagaactca tgagtaatca acttgaaaaa attaaagagc ttattgaacg
     1801 ccgtgccgta gcacgtatcg gaggcggtga aaaagcaatt gcgaagcaac acgaaaaagg
     1861 gaaatacaca gcacgcgagc gtctggctat gctgcttgac gagggtagct tcgaagaaat
     1921 ggacatgttc gttgagcaca gatgcacgaa cttcggcatg gagaaaaaac attacccggg
     1981 agacggtgta gtaaccggct gcggtacgat cgaaggacgt ctggtatatg tgttcgcaca
     2041 agacttcact gtttctgccg gttcactgtc agaaacgatg tcattgaaaa tttgtaaaat
     2101 catggatcaa gccatgaaga tgggcgctcc ctgtatcggt atcaacgact cgggtggtgc
     2161 acgtattcag gaaggtatca acgctttggc aggttatgca gaaatcttcc aacgcaatat
     2221 ccttgcttcc ggtgttatcc cacagatttc aggtatcttc ggtccttgtg ccggcggtgc
     2281 tgtttattct ccggctctga ccgacttcac gctaatgatg gaaggtactt cttatatgtt
     2341 ccttaccgga ccaaaagttg tgaagaccgt aacaggtgaa gacgttagcc aggaaaacct
     2401 cggtggcgca agcgttcact ccactaaatc aggtgtgact catttcaccg ctaaaacaga
     2461 agaagaaggt ttcgaactga ttcgtaaact gttgagttat attcctcaaa acaaccttga
     2521 agaagctcct tatgtagatt gtacagaccc aatcgaccgt ctggaagatt ctttgaatga
     2581 tattatcccc gacagcccta ctaaaccgta tgacatgtac gaagttatcg gcgctattgt
     2641 ggacaacggt gagttccttg aaatccagaa agattatgca aagaatatca tcattggttt
     2701 cgcccgtttc aacggacaat cggtaggtat tgttgccaat cagcctaagt atctggctgg
     2761 tgtgctcgac agcaacgcat ctcgcaaggg tgcacgtttc gtgcgtttct gcgatgcatt
     2821 caatattcct atcgtatcgt tagtagacgt accgggattc cttccgggaa caggtcagga
     2881 atacaacggc gttatccttc atggtgctaa gctattgtat gcttacggtg aagctactgt
     2941 gcctaaggtt actatcacat tgcgtaaatc ttacggtggt tctcacatcg taatgagctg
     3001 taagcaactt cgcggtgaca tgaactacgc atggccgact gctgaaatcg cagtaatggg
     3061 tggagcagga gcagtagaag tattgtacgc acgcgaagcc aaagatcagg aaaatcccgc
     3121 tcaattcctt gctgaaaaag aagcagaata cacgaaactg tttgccaatc cttacaatgc
     3181 agccaaatac ggctacatcg atgatgtgat tgaaccacgc aacacacgtt tccgcgtaat
     3241 ccgtgctttg cagcagttgc agactaagaa attgagtaat ccggctaaga agcatggtaa
     3301 tattccgttg taatcctact tttcacatta aaacaagaac gattatgaac aaaaccaaaa
     3361 tcggaatatt cctttctttg ctgttgctga ttgggctgac ttcttgtgga gagcaaaagt
     3421 cgaacaacaa gctggtactg aacgaaatcc tgatagacaa tcagaataat tttcaagatg
     3481 actacggatt gcacagcgca tggattgaaa tattcaataa atcattcggt agcgccgacc
     3541 tggcagcttg cttgttgaaa gtaagcagcc aaccgggcga tacagttact tactttatcc
     3601 cgaaaggtga tatacttaca ttagtgaagc cacgtcaaca tgcactattc tgggcagatg
     3661 gcgaacctaa ccgcggtact ttccacacca gcttcaagct gaatccggaa acggccaact
     3721 ggatcggtct gtttgactcc ggtagaaagc tgctcgacca gattgtagtg cccgcaggtg
     3781 ttcttggccc caaccagtca tacgctcgtg tcagcgacgg agcagcggag tgggaggtaa
     3841 aaggtggaag tggtgacaaa tacgtgaccc cgagtacgaa caacaaaact cttgacagca
     3901 atgccaagat ggaaaaattc gaagagcatg atgctgacgg tgtcggcatg tccatctctg
     3961 ccatgagtgt agtattctgc ggattgattc ttctctttat tgccttcaag attgtaggaa
     4021 aagtagctgt aaatttgagc aagcgcaatg ctatgaaatc taaaggcatt gacaagcatg
     4081 aagctaagga actgtcacag gctccgggcg aagtttacgc tgcgatttct atggcattgc
     4141 acgaaatgca ggatgaagtg cacgacgtag aagaaacggt actgaccatc actcgcgtaa
     4201 aacgcagtta ctcaccatgg agttcgaaga tttacacttt gcgtgaaact cctcccagaa
     4261 agtaagtcac cttttaaaaa gttaaaacga tgaaagaata taaatataaa atcaacggta
     4321 actcatataa agtaaccatc ggagatattg aagataatat cgctcatgta gaagtgaacg
     4381 gtacacacta taaagtggaa atggagaaac agccgaagcc tgctgccaaa cctgtaacag
     4441 tacgtcctat gcctaatgct cctactgctc ctactcaggt agtgaaaccg actgctccgt
     4501 ctaccggaaa atcaggagtg aaatctccgc tgccgggtgt tatcctcgac atcaaagtga
     4561 atgtaggcga tactgtaaag aaaggacaga ccattatcat attggaagcc atgaagatgg
     4621 aaaacaatat caatgcggat aaggacggta agattactgc catcaacgtc aacaagggag
     4681 actctgttct tgaaggtaat gacctcgtaa ttattgaata atatgggaga ttttataaac
     4741 tttttaggaa ataacctcgc cgacttctgg acatacacgg gctttgcaaa tgctactgta
     4801 gggcatgtcg ttatgattct tgtgggtttg gggttcatct atctggcggt agccaaagag
     4861 ttcgaaccga tgctgctgat tcctatcggc ttcggtatgc tgatcggtaa tatacctttt
     4921 aatatggatg ccggactgaa agtcggtatt tatgaagaag gttccgtatt gaatatattg
     4981 tatcagggag taacttccgg ctggtatccg ccgctcatct ttttgggcat cggcgccatg
     5041 acggacttct cggcacttat ctctaatccg aaattgatgt tgatcggtgc tgctgcacaa
     5101 ttcggtatct tcggtgctta catgatcgca ttggaaatgg gcttcgaccc gatgcaagcc
     5161 ggcgctatcg gtatcattgg tggagcagat ggcccgacgg ccatcttcct ttcttccaag
     5221 ctagcaccta acctgatggg agccattgcg gtgtccgcct actcctatat ggcgttggtt
     5281 ccggtgatac agccgcctat catgcgtctg ctcaccacca agaacgaacg tgtcatccgc
     5341 atgaaaccgc cgcgtgccgt ttctcacacg gagaaggtta ttttcccgat tatcggcttg
     5401 ttgctgacct gcttcctggt tccttccggt ctacctttgt tgggtatgct gttcttcggt
     5461 aacctgttga aagaaagtgg tgtaacccgt cgtcttgcca atacagctag cggtccgttg
     5521 attgatacta tcactatcct gttgggtctg acagtaggtg cttctacgca agcttccgaa
     5581 ttcctgacgc tcgattctat caagattttc gccctcggtg cattgtcatt catcattgca
     5641 actgcatccg gtgtaatctt cgttaagata ttcaatatct tcttgaagaa gggcaacaag
     5701 atcaatccat tgatcggtaa tgcaggggtt tctgctgtcc ccgactctgc acgtatctca
     5761 caagtgattg gtttggaata cgattcgacc aactatttgt tgatgcacgc tatgggtccg
     5821 aacgttgccg gagtgatcgg ttcagctgtt gctgccggta tcctgctcgg attcttgatg
     5881 taagatataa ggaggctgtt tgaacagttc ttaaaataaa aaataagact atcctaaaag
     5941 ccttgaattt ataaaaatca cctttgctac attatagtag taaaggtgat ttttcattat
     6001 aaggacttgc tgtaaaaaag actgtagcta ccatgcccca tgtattgtat tgcgcactgt
     6061 tgtgttacct tctcttatca ttccgttaat ctatccaaaa taatctacga ataattcgta
     6121 aatataatat ttttagtaac ttgcagcaga taagtcaaac aactaaaata aaatattatg
     6181 aaacggatta tcattctgtt ctttctttgt tgtaccattc ctctaatagc gcaacacaca
     6241 gaccctattc aagaagctat ggcaaactac gattatgaga cggccctttc tcttatagct
     6301 caaaaaaaga ctacccctcc cctgctatta cagaaaggca aagcgttgcg tggactagga
     6361 ctcaccacag aggcacttgc tacctatcaa gaaattatct gtaatgatac tacaaatact
     6421 cgtgctttca ttgaagcggc cgaatgttgc cgagcactag ctaaatacaa tcaagcacta
     6481 aaatattatg aacatgcact tgatctgaat ccggaaaaca aatatgtacg tattcaatat
     6541 atcagcttgc ttctctccca acagaagttt agcgaggcgc ttggtgaaag tagtctgatg
     6601 acagaaaaag acagttccgc cattgtcctg catctacaag ctcaaagctt tgaaggaatg
     6661 ggcgaacttc ttcccgctgc aggttgctat tacaatatcc aggctaaata tcccgacgat
     6721 tatctggctg ccagcaaact aggcgctcta aatatatccg gttcctattt cgacgaagcc
     6781 atcgaagcta cagaaaaata ccggcaaatt gacagtacca acatttccgt caaccggcag
     6841 aacgctttag catactgctt gaaacaagac taccccactg ccatccaacg ttatgaatat
     6901 cttgtcagcc aaggagacag ttcttttcat acttgttatt atttaggcat cagttactat
     6961 gcagcagaga agtactacga agctcatgat tttttggaag tcgcccgtaa atatgatccc
     7021 aacaatatca atctccttta ttacctcggt cgcgcctgtt ccaaaacttc ctggaaaaaa
     7081 gagggcgtag actatctgga aaaagccatt gatctatcca ttcccaaaga tagcagtatg
     7141 actcgacttt acatcgggat gaccgactgt tacaagatgg cacaaatgta caaagaacag
     7201 attgcatcca tcaaagaacg ctaccagcgg tatgacaaac aaaaccacaa actattgtat
     7261 gacatggcct atatatactt ctatgacttg aaagataaga aaaatgcgga acgctatttg
     7321 gaagcattcc taaaaacacg tcctaaagac actaaagaag aagcggaaat gaacgagaga
     7381 ggcgaacttg ttttaggaaa atccaattat tataatgccg ccgccaactg gctgaaagat
     7441 attcaaagta aacaaaaaat agaagacttc tttcaaaatt cctctccaca acttcctctc
     7501 ccaaagaaag ataaatagat aagaactata aagcaactaa aaggctgcta ccggtttatc
     7561 ggtagcagcc tttcttttat ttatggaata atccggagat tattactgtg ccaatttgtt
     7621 gtcagaaccg agcacattca gaattttgtg cttgtacagt ttttccatat tgtcacgagc
     7681 cgggccaaga tacttacgtg ggtcgaattc agccggtttt tcagcgaata ccttacgtat
     7741 agcagcagtc atagccagac gagagtcaga gtcgatgttg attttgcaaa cagcagactt
     7801 agcagcttta cgcaattctt cttccggaat gccgatagca gctttcagtg caccaccata
     7861 tttgttgata gtttccactt cttcttccgg aactgaagat gatccgtgaa gaacgatagg
     7921 gaatcccgga agtttttcca ttacagcgtc caatacttcg aaagccaatg gaggaggaac
     7981 catacggcca gtcttcgggt cgatgtggca ttgttccgga gtaaatttgt aagcaccgtg
     8041 agaagtaccg attgagatag ccaaagagtc gcaaccagtg cgagtagcga agtcgattac
     8101 ttcttcaggg tcagtatatg tgtgatggtc ggaagaaact tcatcttcta ccccagccaa
     8161 tacgccaagt tcaccttcta cagttacgtc aaactggtga gcgtattcaa caactttctt
     8221 agtcaatgct acgttttctt cgtaaggaag atgagaaccg tcaatcatca ctgaagagaa
     8281 acctgaatcg atacaagatt tgcaagtttc gaatgtatct ccgtggtcaa gatgaagaac
     8341 gatttccgga tgtgcgcagc ctaattcttt agcatattct acagcaccct gtgccatgta
     8401 acgcaacaaa gtagcgttag catactgacg agcaccttta gaaacctgaa gaatcacagg
     8461 agatttagtt tcaacagcag ccttgatgat agcctgcatt tgttccatat tgttgaagtt
     8521 gaatgctggg atagcatatc cacctttgat agccttagca aacatttctc ttgtgtttac
     8581 caatcctaaa tctttgtaat ttaccatttt gtttaaagtt tattgttagt gaataaaaat
     8641 tctacgcaaa agtaagcatt atccatcgaa taacgaacat cggaaagaaa aatatagtag
     8701 aaaaaggttt aaatcagact gcaaaattta gcaggaatac gagtgtgaca ttagattgta
     8761 atgtccacct tgcaaacttt gggatttatg atttctgaat tctgattgat gccttcggat
     8821 ttatatctcc ttatttatac cttatttttc attcatttga tcaccaaaat ctgcatagcc
     8881 aatcagaaat cagaaattat aaatcagaaa ttttagaaaa cctttttcta tttcacagaa
     8941 aagcattatc tttgcgctct gaaaatgacc attacactat ttcttaccaa aatagtaaca
     9001 gaatataaat taaaaaaaca gatactgaaa tgaaaaaagg ccttcatcca gaatcatacc
     9061 gtccggtagt atttaaagat atgtcaaatg gtgacatgtt tttgtctaga tcaactgtag
     9121 caactaaaga aaccatcgaa ttcgaaggtg aaacttatcc gttgctgaag attgaaatct
     9181 caaacacttc tcacccgttc tatacaggta aatctacatt ggtagatact gcaggtcgtg
     9241 ttgacaagtt catgagccgt tacggtgacc gtaagaagaa ataattcgat ctttcgtgaa
     9301 agatgaaaaa agaggagatt ctcgcagaga atttcctctt tttcgttttc tatattcctt
     9361 aacgtcaagc atcatccaac aagaaatcgg ctatatgacg atgcctgacc ccctccacat
     9421 tatcctgcca caagctgtcc atgctaacta catatttagg ataatggtcg ttaatggcga
     9481 gcaaaggagc aaactccctc tcaacagttg cctgtgaagc taactgatac gttacttgca
     9541 cataaatctt ttcttcccga cggatggcta caaaatccac ttctttatca tcctgtttgc
     9601 ctacatacac ttcataaccc cttcttttca actccagaca gaccagattc tccaacatac
     9661 ctgcaatcaa ccggtcacga tagcccatca cggaataaat caaagaaagg tcgcttacaa
     9721 aatacttctc attcgtctgc agaatttcct ttcctttaat atcataccgg gaaatacgtt
     9781 gaatgataaa agcactttcc aatgcattca gataattata gatggtattc atatccacct
     9841 tccgttgctg acttttgaag taatcggcta tatttttagc gttcagctta ttgcctatat
     9901 tatcgaaaac aaacttcact acccgttcga gcagttccac attccggata ttgtgacgct
     9961 gcaccgtgtc acgaagaatg acagaagaat agatgtcgta gacaatttta tagatagcct
    10021 catatccata atcggcagta tgtatggccg gaaatcctcc catacggaga tatttctgaa
    10081 attcctcctt ccggttgagc gtcggatcat tggcctgcaa gtcatggaaa gtcagatatt
    10141 ctctaaaaga caaggtcatg acatggaaag cgacataccg tcccgttaaa taagttgcca
    10201 gttcggacga taacatacgt gagttggagc cggtcacata aatatccgta tccaaatcta
    10261 ccagaagtga gttgaccact ttttcccaac cgtccacttc ctgaatttca tccaagagaa
    10321 tataatattt acccgcatct cctgcctgcc cccgaatata agcatacaaa gccttcgcct
    10381 ctttcagatc tatccactga aaactttcaa aattcagata gatgatacgt tcttcacgaa
    10441 ctcctctcct caacagttcg tcacgaatca gacgcagcac taccgacttt ccactgcgac
    10501 gaatacccgt tatcactttt acaaacggct tatctataaa aggaacaatt tgttccatat
    10561 actgttcacg attaatcata ttcaaaagtt tttagggtta taagcacaaa gatatactat
    10621 tttcggaaag tttttagggt tataagcat
//
