LOCUS       c00018_gnlPro..        15235 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DNJGOOFC_19.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 17:50:58
            Original ID  :: gnl|Prokka|DNJGOOFC_19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 14827
            Orig. end    :: 30062
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15235
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[24827:29685]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14858
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..15235
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15235
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(27..908)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MRIGKKDIMAFIVLFLATIVCVRYFYKNMSDEQFVATVDPYSLVI
                     PTPTAIFAINRPPVFEKMILPMENIRKAFSDHTPAIFLSLIQQNPDLSSFLIAYYPQGD
                     ILYAPMDSHTAERIFKQLDASFTFPAQQREEASVPVRYYPDVDKHFLGCYYHEGIFVVS
                     YNRKLLVETAKKQQTYPAQIIPELADLISKKGKSGAMNLFIQSASLDLQVQMNDSTEWK
                     MKNQWLAMDLFYNEGSLCCFNEQPYEETLENFYPNLCDTITTRINRLFPQIKTTAQVSH
                     DEAVVYFTVCGN"
     CDS             complement(905..1543)
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MRKEERYKGVLNWFKENVPVAETELHYDDPYQLLIAVILSAQCTD
                     KRVNMITPALFEAFPTPEVMAASTPEVVFEYIRSVSYPNNKAKHLVGMAKMLIEDFKGV
                     VPSDIDELQKLPGVGRKTANVIASVVYDKPAMAVDTHVFRVSNRIGLTNNSKTPLETEK
                     ELVKNIPEELIPIAHHWLILHGRYVCLARKPKCEECGLKPWCKYFLKQT"
     CDS             complement(1712..4225)
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="MKTLKYLLVTMLLLGVCSLTHSQKLSLGIFPEPQEVTISSQTYTP
                     PHGYTLRGINNPDADAVKLLKEALPFAKSGKSLPLEIKKLKDKTPEMQRSGAYTLAITK
                     KGITIGIVDDNSLFYAAQTLKQLAKYDEGKKILPLCSIKDYPDVLFRGTVEGFYGQPWS
                     HADRIEQIRFYGRIKLNTYLYGPKDDPYHSSPNWRNPYPAEEAEHIKELAKEAAHNKVN
                     FVWAIHPGQDIQWDQADSMNILSKFEKMYDLGVRSFAVFFDDISGEGARPEKQAGLLNY
                     IHKEFISKKNDVQPLIMCPTEYNRSWAKTDYLDILGTQLDPAIQIMWTGDRVVADITKE
                     GVEWVNNRIRRPAYIWWNFPVSDYCQDHLLMGAAYGLDTQAAGTMTGFVSNPMEYAEAS
                     KVAIFGVGMYTWNIKNYDPTQAWKDACDFIMPEASMAFRIFCEHNCDPGPNGHQYRREE
                     SANYVAPIQTFLTGYKKNTFPEQSANLLGTLFAQITASPSMIYSQSPNKRLIEQINPWL
                     IQFEFLGKAGTSALHMAHAWYEKDRSYTWQRYLETSALLDSMKLINRTLNQKAQPKGVK
                     VGSKVLHPFIVDLYRQTGRNLLSTDGIAPDEVKVSIPSIFTNIDQLKSQPCAEGDNTVG
                     YVPLFEVVKVQPNQYLGIGWEIQKEAESFCFNLPKSNQPGRVFEWSADGKSWSLIPHVS
                     TENAKDTICAIDPKARYIRMRNNSDQQMELYVLGFTATTKQDPQINEALMMYDMNLDTY
                     KNLNPGEIIHIKCDDINAVSFFLSGSNENLVSITGLSQDGEKNIVYQGNVGYIKLNKTM
                     FEDFSSLEITTIGKEPIHIHQIVRE"
     CDS             complement(4328..5926)
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MIKITYKLILLLGLLAMTVTSFAASEAEYGKVSKAWTLHADGSQE
                     YRSSMELTLFTHTAMNSTYGESFIVYNPDFQTLKIHSSYTRQKDGTIVKTPDNAFVEVL
                     PRFAADAPAYNQLKEMVVVHTGLELGATIYLDYSIITKPGYYPALDINERLQETSPVKE
                     CKVSISVPENSPLAWQLLGSDAKASQATRNGAKEVSWTLRNLPASSREAFLPQNQDGIP
                     RLIASSYSSNKEALSTLNKRFNTSGNYESKTFGSYITEKATSDEEKVNAIRNHVVNNMG
                     YCAIPLACTGYSIRDVDTALRSAYGTLAEKTQLLNVLLNAAGIQSEVVAVYPGNLDIDA
                     CGLSTIKNLAVKATVAGKDKYLSAVSLAPSALTARGELDQVLTLNGTSIALQAEPTIIK
                     ENKAVSVSKNEAQNGFAICTLPAITGGIDSWGMSALNSKRSNLFELPSLIKEEVTYTVT
                     PAEGMKLQTSTKEQVISKPFGKVTRTITPRGNTIEVVRTIELDKQQFTPAEYSDVRSLI
                     HEWTNPDNRVLLFSL"
     CDS             complement(5940..7901)
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MKRILTITAVSLLALSPMYGQDSCRYPQDPTLEKSQAYAGYDCVT
                     LLDSTAVTVQPTGSGGFAVCKAFKVQTSKGAVANRIIKYDYDPLTAHAEFRYATIYRAN
                     GDVINLDVTQACDYAAPARAIYWGARQIMLEVGRLQPGDIVEYEIAKKGFTYALLTASD
                     DDERFIPPMRGQFYDIVPFWATEPTVRKVYRVSMPIEKELQFQFYQGECTSSMRYEDGR
                     KVYTFASDDILPFAKEPNMVDLFDAAPKLMMSSTPRWEDKSLWFNKVNEDYGSFTAIPE
                     AQKKVDELIKGKKTEMEKIAVLTHWVADNIRYSGISMGKGEGFTLHNLKMNYTDRCGVC
                     KDIAGTLIAFLRMAGFEAYPAMTMAGSRVESIPADHFNHCVAVVKLASGTYMPLDPTWV
                     PFCRELWSSAEQQQNYLPGVPEGSDLRLTPVSAPENHYVRIHADNRLDEKGTLRGQFTI
                     TAEGQSDSNIRRIFTTGWQSDWQNTMEKQLLAVSPNAKLLRVDYGKDPKNYQAAPIKIT
                     FSYEIPDYAIIAGDQMLIKPLVMNNLYNQVKSFLRIDTKPENRAYGFKDACSRLVEQDE
                     TIRLPKGYTLLNAPKNDVLQSNAADFEGSLSQEGNQNIVLRQKLALKKRVYDAADWKGF
                     RSAVNAYKSYGDYLIIKK"
     CDS             complement(7904..8902)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 53.3; E-value:
                     5.7e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_17"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-17, bitscore:
                     53.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIQEDLQAFLAEWHDPSPFLEVQTSGSTGTPKRMRVRKDRMLNS
                     ARLTCDYLGLKKGDKALLCMPLRYIAGKMMVVRSLYAGLDLEVCEPSGHPLADWGDTPL
                     RFAAMIPLQVYNTLRVPEERKRLEQTDILIIGGGAIDAALEQEIRQMPNTVYSTYGMTE
                     TLSHVALRRLNGPEASPYYHPFPSVTLSLSPDNTLVIDAPLVCDERLVTNDVARLLPDG
                     SFAIIGRKDNIINSGGIKIQIEEVEERLRPYLDRPYAITATPDPRLGEAVVLLLASNLR
                     GEMLTEVLANLPKYLRPRHIIKVSEIPQTGSGKIDRAACRELARNIITKTL"
     CDS             complement(8906..9964)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_18"
                     /sec_met_domain="MR_MLE_C (E-value: 3.6e-30, bitscore:
                     95.7, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKERLYRIEVVPRCLTFKRPAGTSRGVYTTRKLWEVRIRKEDEP
                     SVIGIGECAPLPDLSCDYGVDYEITLSKACLDLEQKGYVDTESLRHYPSILFGLETAMR
                     HYEQGGWRHYDTPFSQGQAGIPINGLIWMGDYKYMLEQVEEKMKEGFRCVKLKIGAIDF
                     DRELSLLKHIRAHFSAKEIELRVDANGAFTPSEAMDKLKRLAEMDLHSIEQPIRAGQLE
                     EMARLAAESPLPIALDEELIGCNAPDEKRRLLETIHPQYIILKPSLHGGIAGCTEWVHL
                     AETILGSTPEQPKWWVTSALESQIGLNAIAQWCATLGNPLPQGLGTGEIFKDDKHKLIQ
                     RKGDTIWFTNDL"
     CDS             complement(10001..10825)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_19"
                     /sec_met_domain="ECH_1 (E-value: 6.1e-82, bitscore: 265.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTE
                     MSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNVKGRGGYVGKDGVPRLNVLDVQKQI
                     RSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP"
     CDS             complement(10829..12517)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_20"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-07, bitscore:
                     21.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLIEHGVSNIVLCPGSRNSPIVHTLANHSFFN
                     CHSVTDERSAGFFAVGLALHGGKPAAVCCTSGTALLNIHPAVAEAFYQKVPLVVISADR
                     PAAWIGQMDGQTLPQPGVFGSLVKKSVQLPEIHTDQDEWYCNRLINEALLELNHHGKGP
                     VHINVPISEPLFQFTTPELPKVRVITRYQGLNVYDRKYDDLIERLNKYSKRMMIAGQMS
                     LIYLFEKKICKLLYKHFTWLSEHIGNRIVPGLPIKNFDAILYATPEEEKEKLVPELVIT
                     YGGHIVSKRLKEFLRKHPPKEHWHVSLDGEVADLFGSLTTVIEMDPFEFLEKIAYMLEN
                     RQIEYPKAWEYKSRNLPEPEFAYSEMAAIGGLIRSLPAESALHLGNSSTVRYAQLYTVP
                     ETVEVCCNRGTSGIEGSLSTAIGYASASQKLNFIVIGDLSFFYDMNALWNGNLHNNLRI
                     LLLNNGGGEIFQALPGFKMNERTHRYVTASHQTSAEGWATERGFSYSAVHNAEELAAAM
                     SAFTQTEQPSEHPLFMEVFTDKAEDVRLLKEYYHQLKNSSQAQNI"
     CDS             complement(12532..13629)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_21"
                     /sec_met_domain="Chorismate_bind (E-value: 1.5e-54,
                     bitscore: 175.8, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPRDSYEIIDTLIKQGRSFAIWRIPGEDRLYFRMQSTGSPCLLY
                     DIKDLNERSGFVIAPFQVTAERPIVLIQPDCFEIPSESDWDFSREKNEFPSNEIEIPSE
                     SEEKERYAYHFSLFTSPLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAEERYIRSYVY
                     LCHTPETGTWMGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQLVAS
                     YIRRQLSTLGITPEEKGPYSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPAVCGL
                     PKEEAYHFIIENEGYDRSYYSGFIGWLDPKGKTDLYVNLRCMNILPQTFTLYAGGGLLA
                     ASQLEDEWQETEDKLDTMRRIVGNL"
     CDS             complement(13626..14858)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_22"
                     /sec_met_domain="HBT (E-value: 3.3e-17, bitscore: 53.4,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDKKEITPRTHAALLKAQQMGVHVVLASGR
                     PTNGVQPLAEALELNHYGGFILSYNGGQIINAQTGELMFEKRIDPAMIPYLNRKAKENG
                     FAIFTYHKDYILTDSPENKHVQEEAELNKMRIIGVENFPEAVDFAPCKCILTSDDENNL
                     VGLENHWKKRLDGVLEAFRSEDYFLEVAPHFINKGNTLAVLMEMLNITTEEVVAIGDGV
                     ADVSMLQLAGTGVAMGNARDSVKACADFTTLPNNMEGVAAAIEKAILATIKPTEVPLDQ
                     LNARAKHALMGNLGIQYTYASEDRVEATMPVDERTRQPFGILHGGATLALAETVAGLGS
                     MILAKPDEMVVGMQVSGSHMSSAHEGDTVRAVGTIIHKGRSSHVWNVDIFTSTDKLVSS
                     VRVINSILKKK"
     CDS             15156..15233
                     /locus_tag="ctg18_23"
                     /transl_table=11
                     /translation="MARSTFKVLFYVNGSKEKDGIVPIMG"
ORIGIN
        1 gcattcaaga aagaagggac tgaagcttaa ttcccgcaaa ccgtaaaata gaccacggcc
       61 tcgtcatgac tgacttgtgc cgtggttttt atttgtggga atagccgatt gatccgagta
      121 gttatcgtat cgcataagtt ggggtaaaag ttctccaagg tttcctcata gggctgctca
      181 ttgaagcagc aaaggcttcc ttcattatag aataaatcca ttgccaacca ttgatttttc
      241 attttccact ccgtcgagtc attcatttga acctgtaaat ctaaagaggc gctttggatg
      301 aagagattca tcgcgccact cttgcctttt ttactaatta gatcagctaa ttccggaatg
      361 atctgtgcgg ggtacgtctg ttgctttttc gctgtctcta ccaataattt tcgattgtag
      421 gacaccacga atataccctc gtggtagtaa caacctagaa aatgcttatc aacatccgga
      481 tagtatctaa caggaacgga agcttcctct cgttgctggg caggaaaagt gaaagaagcg
      541 tccagttgct tgaaaatacg ctctgccgta tgactatcca taggggcgta caagatatcc
      601 ccttgtggat aataagcgat caagaaagac gataaatccg gattttgctg tattaaagag
      661 aggaaaatag cgggcgtatg atccgagaac gccttgcgta tattctccat gggtaatatc
      721 atcttctcga atacaggagg acgattgata gcaaaaattg ctgtgggggt cgggatgacc
      781 aagctatagg gatctaccgt ggcgacaaat tgctcgtcgc tcatattctt gtaaaagtac
      841 ctcacgcaaa cgatcgtagc caaaaacaag acaatgaatg ccattatgtc tttcttgccg
      901 atcctcatgt ttgctttagg aagtatttac accaaggctt taatccgcat tcctcacatt
      961 tcggtttccg ggcgaggcaa acatatcttc catgtaatat caaccagtga tgggcgatgg
     1021 ggatcagttc ttccggaatg ttcttcacta gctccttttc cgtttccaag ggtgtcttgc
     1081 tattattggt caagccgatc cggttggaga cacggaatac gtgcgtatct accgccatgg
     1141 ctggcttgtc atatacaacg gatgcgatta cgttcgcagt ttttcttcct acacccggaa
     1201 gtttctgtag ctcgtcaata tcggagggaa ccacgccttt gaagtcctct atcagcatct
     1261 tcgccatacc taccagatgt ttagccttat tgttcgggta agatacgctt cgtatgtatt
     1321 caaagacgac ttccggtgtg ctagctgcca ttacctcggg agtagggaaa gcctcgaaca
     1381 gggcaggagt gatcatattc actcgcttat ccgtgcattg tgcggatagg attaccgcta
     1441 tcaataattg atatggatcg tcataatgta gttcagtctc ggctaccggt acgttttcct
     1501 taaaccagtt taatacgcct ttatatcttt cttcttttcg cattgttttt tcggtttcta
     1561 tttttcgcat cctaaaggta taacttttaa aaggaatata caagcggaga tgtgccaaaa
     1621 ataagatact cccgaattgt acgaataaat aaaaaagtac cgatctcctt cttccatcta
     1681 agagagaaag aaatcggtac ttttttattt attattccct aacgatctgg tggatatgta
     1741 taggttcttt tcctattgtg gtgatttcta aagaagagaa atcctcgaac atggttttat
     1801 ttaatttgat gtagcctacg ttcccttgat agacgatgtt tttctcacca tcttgagaga
     1861 ggccggtgat agataccaaa ttctcgttac ttccggagag gaagaaagat acggcgttga
     1921 tatcatcgca ttttatgtga attatttctc ccggattcaa gttcttatac gtatctaggt
     1981 tcatatcgta catcataaga gcctcattga tttgcgggtc ttgtttggtt gtcgccgtga
     2041 atcctagtac atatagctcc atttgctgat ccgagttatt tcgcatacgg atataacggg
     2101 ctttcggatc gatggcgcag atcgtatcct tagcgttttc cgtggagaca tgggggatta
     2161 ggctccagct ctttccgtca gcagaccact cgaatacccg tccgggttgg ttgcttttcg
     2221 gaagattgaa acagaaggat tccgcttctt tctggatttc ccagccgata cccagatatt
     2281 ggttaggttg taccttgact acctcgaata ggggaacgta accgaccgta ttgtcaccct
     2341 cggcacaagg ctggctcttt aattggtcga tattcgtgaa tatggaaggg atgctaacct
     2401 tcacctcgtc cggggcgata ccgtccgtag atagcaggtt acgacctgtc tgacgatata
     2461 agtctacgat gaaagggtgt aagactttcg atccgacttt cacgccttta ggctgtgcct
     2521 tctggttcag cgtgcggttt atcagtttca tgctatctag caaggcagat gtttccagat
     2581 agcgttgcca tgtataagac cggtctttct cataccaagc gtgcgccata tgcagagcac
     2641 ttgtaccggc ttttcctaag aactcgaatt ggataagcca tggattgatt tgttcgatca
     2701 agcgtttatt gggactttgg ctgtagatca tgcttgggga agccgtgatt tgagcgaata
     2761 aggttcccag aagatttgcg ctttgctccg ggaacgtgtt tttcttatat ccggtaagga
     2821 atgtctggat aggagccaca tagttagcag actcttcccg gcggtattga tgtccgttcg
     2881 gacccggatc gcagttatgc tcgcagaaaa tgcggaaagc catggaggcc tccggcataa
     2941 taaagtcgca agcgtctttc catgcctgtg taggatcgta attcttgata ttccaagtgt
     3001 acattccaac gccgaatata gcgaccttgg aagcctcggc atattccata ggattggata
     3061 cgaatccggt catggtgccg gcggcttgcg tatctaggcc gtaggcggct cccatcaaca
     3121 aatgatcttg gcaataatcg cttacgggga agttccacca gatataggcg ggacgacgga
     3181 tacggttgtt tacccattcg acgccttctt tcgtgatatc ggctacgaca cggtctccgg
     3241 tccacatgat ttggatggcg ggatcgagtt gggtaccgag gatatccaga tagtcggtct
     3301 tagcccatga acggttgtat tcggtagggc acatgatcag gggttgcacg tcatttttct
     3361 tgctgataaa ttccttatgg atgtaattca ataagccggc ttgcttttcc gggcgggctc
     3421 cctctccgga tatatcatcg aagaaaacgg cgaaagagcg tacgcccaaa tcgtacattt
     3481 tctcgaattt ggaaaggatg ttcatgctgt ccgcctggtc ccattgaata tcttgtcccg
     3541 gatggatggc ccaaacgaag tttactttgt tatgggcggc ctctttcgct agttccttga
     3601 tatgctcggc ttcctcggcg ggataagggt tgcgccagtt gggagaacta tgataaggat
     3661 catctttcgg accatagaga taagtgttta gcttgatcct tccgtaaaag cggatttgct
     3721 cgatacggtc ggcgtggctc caaggctgtc cgtagaatcc ttccacggta ccccggaata
     3781 atacgtccgg atagtctttg atcgagcaga gaggcaggat ctttttaccc tcgtcatatt
     3841 tagctaattg cttgagggtt tgggcggcgt aaaacaagga attatcgtct acgatcccga
     3901 tcgtgatacc ttttttagtg attgctagtg tgtaggcccc cgatcgttgc atttctggag
     3961 ttttgtcttt tagtttcttg atctctaaag ggagagattt gccggattta gcgaaaggta
     4021 gcgcttcttt aagtagtttg accgcatctg cgtccggatt atttataccc cgtagggtat
     4081 atccatgggg cggtgtgtat gtttggctgg aaatagtcac ctcttggggc tcggggaaga
     4141 ttcctaggga tagcttttgg ctatgcgtta ggctgcaaac gcctagaagg agcatggtga
     4201 cgagtaaata ctttagtgtt ttcatatgcg atatgattta atgttaacgt tcgtaaatgt
     4261 agggaataat tagacacgaa gcacacggag ggcacggatt tgttccgtgt gctccgtgtt
     4321 ttagatctta tagggagaat agcaataccc ggttatccgg atttgtccat tcatggatca
     4381 agctacgcac gtcgctatat tcggcgggag tgaactgttg cttgtccaac tcgatcgtac
     4441 gtactacctc gatcgtattt cctcttggtg tgatcgtgcg ggttacttta ccaaaaggct
     4501 tgcttatcac ttgctctttt gtggaggtct gcaacttcat gccctcggcg ggagtaaccg
     4561 tgtaggttac ctcttccttg atcagggagg ggagttcgaa taagttggaa cgcttgctgt
     4621 tcaaagcgct catgccccag ctatcgatac cgcctgttat agccggaagg gtacagatgg
     4681 cgaatccgtt ttgtgcttcg ttcttggaga cgctgacggc tttattctcc ttgatgatcg
     4741 taggctctgc ctgtagggcg atcgacgtgc cgttcaacgt gagtacctga tctaactcac
     4801 cccgggctgt taatgcggaa ggggcaaggc tgaccgccga aaggtatttg tctttccctg
     4861 cgacagtcgc ttttacggca agattcttga tcgtgcttaa tccacaagcg tctatatcca
     4921 gattccctgg atatacggcg actacttccg attgaatgcc ggcggcgttc aataagacgt
     4981 tcagaagctg ggtcttctcg gctaatgtac cgtaagcact gcgaagggcc gtatcgacat
     5041 cgcggatgga ataacccgta caagcgaggg ggatggcgca atatcccatg ttgttgacta
     5101 catggttccg gatggcgttc accttctctt cgtcgctagt agccttttcc gtgatataag
     5161 agccgaacgt tttgctctcg tagtttccgg aagtgttaaa acgcttattt agcgtagata
     5221 atgcctcctt gttggaacta tagcttgaag cgattaggcg gggaatcccg tcttggtttt
     5281 gaggaaggaa agcttcccgg gaagaggccg gcaggttacg taaagtccag cttacctctt
     5341 tagcgccgtt tcgggtggct tgggatgctt tcgcgtcgct acccaataat tgccaagcga
     5401 gcggactgtt ttccggtacg gagatagaga ccttgcattc cttcacggga gaagtctctt
     5461 gtagtcgctc gttgatatcc agagccggat agtagcccgg ttttgtgata atagagtaat
     5521 ccaagtaaat cgtggcccca agttctaggc cagtgtgtac cacgaccatt tccttgagtt
     5581 ggttataggc cggagcgtcg gcggcgaaac ggggtaggac ctctacaaag gcgttatcgg
     5641 gtgtctttac gatcgtaccg tctttctgcc ttgtatagga tgagtggatc ttcagtgttt
     5701 ggaaatcggg attgtagacg ataaaactct cgccatacgt gctattcatc gcagtgtgcg
     5761 tgaagagcgt caattccatg gaggatcggt attcttggct accgtcggca tgcaaggtcc
     5821 aagctttcga taccttcccg tactcagcct ccgatgcggc gaatgaagta accgtcatcg
     5881 ctaacaagcc taggagaaga atcagtttat aggttatctt aatcattgtc tttctgtttt
     5941 tatttcttga taatcaaata gtcaccataa ctcttataag cgttcacggc ggaacggaaa
     6001 cctttccagt cggctgcgtc gtagacacgc ttcttcaacg ctagcttctg gcgcaagacg
     6061 atgttctgat tgccttcctg cgaaagggaa ccttcgaaat cggccgcatt gctttgcagg
     6121 acgtcattct tcggggcgtt caagagggta tagcccttgg ggaggcggat ggtctcatct
     6181 tgttctacca aacgggagca agcatccttg aatccatacg cacggttttc cggtttcgta
     6241 tcgatacgca agaaactctt cacttgattg tagaggttat tcatgactag cggcttgata
     6301 agcatctggt ctccggcgat gatcgcgtaa tcggggatct cataagagaa cgtgatcttg
     6361 ataggggccg cttgatagtt cttcgggtcc ttaccgtaat ctacacgaag cagtttggcg
     6421 ttgggggata cggccagcaa ttgcttctcc atcgtgttct gccagtcgga ttgccatccg
     6481 gtggtgaaga tgcggcggat attgctgtcg gattgtccct cggcggtgat cgtgaattgt
     6541 ccgcggagcg tgcctttctc gtctaggcgg ttgtcggcgt ggatgcggac gtagtggttc
     6601 tccggggcgg agacaggggt taagcggagg tcggagcctt cgggcacacc cgggaggtag
     6661 ttctgctgtt gctcggcgct actccataat tcccggcaga aaggaaccca agtcgggtcg
     6721 agaggcatat acgtgccgct agccagtttt accaccgcca cgcaatggtt gaaatggtcg
     6781 gcggggatgc tttctacacg gcttcccgcc atggtcatcg ccgggtaagc ctcgaagccg
     6841 gccatgcgga ggaaggcgat caacgtaccg gcgatatcct tgcagacacc gcaacgatcg
     6901 gtataattca ttttcaggtt gtgaagcgtg aaaccctcgc ctttacccat cgagattccg
     6961 gagtaacgga tgttatcggc cacccagtgg gtcagcacgg ctatcttctc catttccgtt
     7021 ttcttgcctt tgatcagctc gtctaccttt ttctgggctt ccgggatcgc agtaaagctt
     7081 ccgtaatcct cgttaacctt attgaaccaa agggatttat cctcccagcg gggagtactg
     7141 gacatcatga gcttcggggc agcgtcgaat aggtctacca tgttcggttc cttggcgaaa
     7201 ggaaggatat cgtcggaggc gaaggtatat actttccgtc cgtcctcgta tcgcatcgaa
     7261 gaggtacatt cgccttggta gaactggaat tgcaactctt tctctatcgg catggatacc
     7321 cggtacacct tgcgcacggt aggctcggta gcccagaagg ggacgatatc gtaaaattgt
     7381 cctcgcatag gagggatgaa acgctcgtcg tcgtcactcg ccgtcagcaa ggcgtaggtg
     7441 aaaccttttt tggcgatctc gtactccacg atatctcccg gttgcaagcg gcccacttcc
     7501 agcatgatct gccgggcgcc ccagtagatg gcacgtgcgg gggcggcgta gtcgcaagct
     7561 tgggtcacgt cgagattgat cacgtcgcca ttcgcacggt agatcgtggc gtaacgaaac
     7621 tcggcgtgcg ccgtcagcgg gtcgtaatcg tatttgatga tacggttggc gacggctcct
     7681 ttggaagtct gtaccttaaa agccttgcat acggcgaaac ccccggagcc ggtaggttgt
     7741 accgtaacgg cggtgctatc cagcaaggtg acgcagtcgt atcctgcata ggcttgcgat
     7801 ttctccaagg taggatcttg cgggtatcgg caagaatcct gcccgtacat aggcgataag
     7861 gccaataggg agaccgcagt gattgttaga attcttttca tgtttatagt gtttttgtaa
     7921 tgatatttct cgctagctcc cggcaggcgg cacggtcgat cttgccgctt ccggtttggg
     7981 ggatctcgct tacctttatg atgtgcctcg gacggaggta cttgggcagg ttggcgagaa
     8041 cctctgttag catctcacct cgtaggtttg aggcaagcag tagcacgacc gcctctccca
     8101 accgagggtc gggggtggcg gtgatggcat aggggcggtc gaggtagggc cgtagccgct
     8161 cttccacctc ctcgatctgg atcttgatac ctccgctatt gatgatatta tctttccttc
     8221 cgataatggc gaaactcccg tccggcagca ggcgggcgac atcgttcgtc accagccgct
     8281 cgtcgcaaac caatggggcg tctattacca aggtattgtc cggtgacaag gataacgtca
     8341 ccgaggggaa gggatggtaa tagggcgagg cttccggccc gttcaaccgg cgcagggcga
     8401 cgtgagacag cgtctccgtc attccgtagg tggaataaac cgtgtttggc atctgccgta
     8461 tctcctgttc caaggccgcg tcgatcgccc cgccgccgat gatcaagata tccgtttgct
     8521 ccagccgttt acgttcctcg ggtactcgca acgtattgta aacctgcaaa ggaatcatgg
     8581 cggcaaagcg caggggcgta tccccccaat ccgccaacgg gtgtccggag ggttcgcaca
     8641 cctccagatc cagtccggcg tatagggagc ggaccaccat catctttccg gctatatagc
     8701 gtaggggcat acataacaag gccttgtcgc ccttcttaag ccccagataa tcgcaggtaa
     8761 gccgggcgct gttcagcatc cggtccttgc gtactcgcat ccgcttgggc gtaccggtgg
     8821 agccagaggt ctggacttcc agaaaagggg agggatcgtg ccattcagct aagaatgcct
     8881 gtaaatcttc ttgtatcggc ataggtcaaa ggtcgttggt gaaccagatg gtgtctcctt
     8941 ttcgttggat caacttatgt ttatcgtcct tgaaaatctc gccggttccc agaccttgcg
     9001 gtagcgggtt acctagcgtg gcgcaccatt gggcgatagc gttcagtccg atttgcgatt
     9061 ccagagcgga ggtgacccac catttaggtt gttcaggggt actccctaag atagtttccg
     9121 ctaagtgaac ccattccgtg catccggcga tacctccgtg gagggaaggc tttaatataa
     9181 tgtattgggg atggatcgtt tccaacaacc gccgtttctc gtccggggcg ttacagccga
     9241 tcagttcctc gtcgagagcg atgggaaggg gtgactctgc cgcaaggcgt gccatctctt
     9301 ccaactgccc ggcacggata ggctgctcga tggaatgcaa gtccatctcg gcgagccgct
     9361 tcagtttgtc catcgcctcc gagggtgtga aagcgccgtt ggcatctacc cgaagctcta
     9421 tttccttggc agagaaatgc gcacggatgt gtttcaataa agagagttcc cggtcgaaat
     9481 cgatagcgcc gatcttcagc ttgacgcagc ggaagccctc cttcatcttt tcctctacct
     9541 gttccagcat gtacttataa tcgcccatcc agatcagtcc gttgatgggg atgcccgcct
     9601 gcccctgcga gaagggcgtg tcgtaatgcc gccaaccgcc ctgttcataa tggcgcatgg
     9661 ccgtctccag cccgaaaagg atggatgggt aatggcgcaa agattcggtg tcaacatatc
     9721 ccttctgttc cagatcgagg caagccttgg ataacgtgat ctcgtaatcc actccataat
     9781 cgcaactgag atccggcagg ggggcacatt ctccgatacc aataaccgag ggttcgtctt
     9841 ccttacggat tcggacctcc cacaatttcc gggtcgtgta aacaccccgt gaggttcctg
     9901 ccggtcgctt gaaagtcaag caccggggaa ccacctcaat cctatataac ctctccttta
     9961 ccattcattc ttaattattc attattcatt ctcaatcccc ctacgggaat ttcgggtaat
    10021 cctcgaagcg gggacggcgt ttctccaaga atgccttacc gccttcctgc gcctcgtccg
    10081 tcatatagta aagcatggta gcgtctccgg ccaactcctg tataccggcc tgtccgtcca
    10141 actcggcgtt taagcccgcc ttgatcatgc gcaaagccaa cgggctaagc aacatcatct
    10201 cctcggccca ttgaacgtac tcgtcctcta atttatccaa ggggactacc ttatttacca
    10261 gacccatatc caaagcctcc tgcgcattgt acttgcggca taggaaccag atctcacggg
    10321 cctttttctg tccgaccaca cgggcgaggt aagaagagcc gaacccggcg tcgaagctac
    10381 ccacacgagg accagtctgt ccgaagatag cgttctcgga agcgatcgta aggtcgcaaa
    10441 ccacgtgcaa tacgtgtccg ccgccgatag cgaaaccatt cacggccgcg atgacgggtt
    10501 tcgggagaga gcggatctgc ttttgtacgt ccaatacgtt caagcgaggt acgccgtctt
    10561 tacccacgta gccgccacgt cctttcacgt tcatatcgcc tcccgcgcaa aaggccgtat
    10621 ctccggctcc tgtcagaacg actacgttaa tgtccgggcg ttcccggcag atgtaaaagg
    10681 cgtcgctcat ctccgtggtc gtagtcgggg taaaagcgtt gcgataccgt tcccggttga
    10741 tcgtaatgcg ggcgatgccg ttgtagaaat caaataagat ctcctcatat tccttgatgg
    10801 ttgtccattc tcttttcgtt tccatatatt atatgttttg tgcttgggat gaatttttta
    10861 gttgatgata atattccttg agcaatcgta cgtcttccgc tttgtccgtg aaaacctcca
    10921 tgaatagggg atgttcgctc ggttgctccg tttgggtaaa ggcgctcatc gccgctgcca
    10981 actcctcggc attatggaca gcggagtagg agaatcccct ttccgtggcc catccctccg
    11041 ctgaggtctg gtgggaggcg gtaacgtaac ggtgcgtacg ctcgttcatc ttgaatcccg
    11101 gcaaggcttg gaagatctcg ccacctccgt tgttcaagag caggatgcga aggttattgt
    11161 gcaagttacc gttccacaac gcattcatat catagaagaa actaagatcg cctataacga
    11221 taaagtttag tttttgcgag gccgaggcgt atccgatggc cgtagacaag gagccttcga
    11281 tcccgctcgt acctcggtta caacaaacct caaccgtctc gggtacggtg tacaattgcg
    11341 cgtaacgtac ggtggagcta ttccccagat gcaaggccga ttcagccgga agcgagcgta
    11401 tcaaaccacc gatcgccgcc atttcggagt aagcgaactc cggctccggc aggttccggg
    11461 atttgtattc ccaagccttc ggatattcaa tctgcctatt ctccagcata taagcgattt
    11521 tctccagaaa ctcgaaaggg tccatctcga tcaccgtggt caggctaccg aataaatccg
    11581 ctacctctcc atccaatgag acatgccaat gctccttagg cgggtgtttc cgcaaaaact
    11641 ctttcagccg cttggagaca atatggccgc cgtaggtgat tacgagctcg ggaactagct
    11701 tctctttttc ctcctccggg gtagcgtaca ggatagcgtc gaaattcttg atcggcaatc
    11761 ccggtacgat ccggttgccg atgtgctcgg agagccaagt gaaatgcttg tatagtaact
    11821 tgcatatttt cttctcgaag agatagatca agctcatttg tcccgctatc atcatccgct
    11881 tgctatattt gttcaagcgc tcgatcaggt catcatattt ccggtcgtac acgttcaagc
    11941 cttgataacg ggtgattacc cgtaccttcg gcaattcggg tgtcgtgaac tgaaataaag
    12001 gctcggagat cggaacgttg atatgcaccg gtcctttgcc gtgatggttc agttccaaca
    12061 aagcctcgtt gatcaatcga ttacaatacc attcatcttg atccgtatgt atttccggta
    12121 actgcaccga tttctttacc agcgagccga acaccccggg ttgcggcaag gtctgtccgt
    12181 ccatttgccc gatccatgcg gcggggcggt cggcggatat cacgacaagc ggaactttct
    12241 gatagaaagc ctccgctacc gccggatgta tattcagcaa ggccgtgccc gaggtacagc
    12301 aaacagccgc cggcttacct ccgtgcaacg ctagccctac ggcaaagaat cctgcgcttc
    12361 gttcatccgt tacggaatgg caattgaaga acgaatggtt tgccaatgtg tgcacaatcg
    12421 gagagttccg gcttcccgga catagcacga tattacttac gccgtgctct atcagcaagg
    12481 ctaccaattg aaggatgttc tttttatcgc tatacattat atgatataaa attataaatt
    12541 acccactatt ctccgcattg tatctaattt atcctctgtc tcctgccact catcctctag
    12601 ctgcgaggcc gccaacagac cgcctccggc atacagcgta aaggtttggg ggaggatatt
    12661 catgcaacgg aggtttacgt acagatctgt tttgcctttg ggatccagcc aaccgatgaa
    12721 accggagtaa tagctacgat cgtacccctc attttcgatg atgaaatgat aagcctcctc
    12781 cttgggaaga ccgcagacgg ctggagtagg gtgtaatagt tgaaggacat cacccagctt
    12841 ctcgggattc ggcaaggaga agaagaaatc acttttcaaa tgagaaacct ctccggcccg
    12901 ggctgaataa ggccccttct cctcgggagt aatacccaag gtggacagct ggcggcgtat
    12961 ataggaggcg actaattgct gttctctcca attcttatgg tcccagcttt tcggtaattt
    13021 cccgtctcgt aaggattggg ttccggccaa agctaccgtt tgccagtcac ctttctcgcc
    13081 ggataacaag atttccggtg tcccacccat ccaagttccg gtttccgggg tatggcaaag
    13141 gtagacatag gagcggatat atcgttcttc cgcggcgaag aatgccttgc cgggtgagaa
    13201 agagggatct ttccggatcg ttttgctacg ggataggact agtttatctt ggcttccttt
    13261 tagcaaaggg ctggtaaaca gggagaaatg gtaagcgtat cgttccttct cctcggattc
    13321 ggacgggatt tcgatttcat tcgaagggaa ttcgtttttc tctcgagaga aatcccaatc
    13381 ggattcggag gggatttcaa agcaatccgg ttggattaaa acgataggtc gttccgctgt
    13441 cacctgaaac ggagcgatta caaaaccgct ccgttcattt aagtctttta tgtcgtataa
    13501 taggcaagga gagccggtgc tttgcatcct gaaatagagc ctatcctcac cgggaatacg
    13561 ccaaatagcg aaactccggc cttgcttgat caacgtgtct attatttcgt aagaatctct
    13621 tggaatcatt ttttctttag tatgctattg attacccgta ccgaggaaac cagtttgtcg
    13681 gtagaggtga atatgtctac gttccacaca tgggatgaac ggcctttgtg gataatcgtc
    13741 ccgacggcac gtaccgtgtc tccctcgtgg gcggacgaca tatggctgcc gctaacttgc
    13801 atgccgacta ccatctcgtc cggtttcgcc agaatcatgg aacctagtcc ggccacggtc
    13861 tccgccaaag ccagcgtagc gcctccgtgc aagataccga aaggctggcg ggtccgttcg
    13921 tctacaggca tggtcgcttc cacacgatcc tctgacgcat aggtatattg aatgcctaga
    13981 ttacccatta aggcatgttt ggcccgtgcg tttagttgat ctaacggaac ctctgtgggt
    14041 ttgatcgtgg caaggatcgc tttctcgatc gctgccgcca caccttccat attattgggt
    14101 aaggtcgtga aatcggcaca agcctttacg gaatcgcgtg cgttacccat cgccacgccg
    14161 gtaccggcta attgaagcat ggatacgtcg gctacgccat caccgatagc gacaacctct
    14221 tcggtcgtga tattcagcat ctccatcaat accgccaacg tatttccctt attgatgaaa
    14281 tgaggagcta cctccaagaa atagtcctcg gagcggaaag cttccaacac cccgtccaga
    14341 cgtttcttcc aatgattttc gagacccacc agattgttct cgtcatcgct ggtaagaata
    14401 cacttacagg gtgcgaaatc caccgcttcc gggaaattct ccacaccgat gatgcgcatc
    14461 ttattgagtt cggcctcctc ttggacatgc ttgttttccg ggctatcggt caggatatag
    14521 tccttgtgat acgtgaagat cgcgaaaccg ttttccttcg ccttccggtt caaataagga
    14581 atcatggccg gatcgattcg tttctcgaac atcaattctc cggtctgggc attgatgatc
    14641 tgacctccgt tataagataa tatgaaacca ccgtaatgat tcaattcaag agcctccgcc
    14701 aagggttgaa ccccgttggt gggtcggccg gatgccaata caacatgaac tcccatctgc
    14761 tgagccttta acaaggcggc atgggtccgg ggagttatct ctttcttgtc gttaagcaac
    14821 gtcccatcta cgtctaagac taataatttg tacttcatgg cgtcttattt ttatggttta
    14881 gaatacaaat atacataaaa tctctggaat aacctcgaaa atcgggagaa atggcactaa
    14941 atgacttaat gtcaataccg ttagggtgtc agatgctgcc aagccgaaaa tgctgaaaaa
    15001 gcaaagaaaa gcagagctaa gcaggagaac ggtttgcaaa tcattacccg ctgaaaggtg
    15061 atttttaaca catggcactg atatttactt cgtatggctt tgattggctt acaaggtcta
    15121 actcgttgat atttaacttt gcaaaaaaaa cgagtatggc aagaagtaca ttcaaagtgc
    15181 tgttctacgt gaacggcagc aaggagaaag acggcattgt ccccatcatg ggacg
//
