LOCUS       gnlProkkaJJMKIFCH_16   12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJMKIFCH_16.
ACCESSION   gnlProkkaJJMKIFCH_16
VERSION     gnlProkkaJJMKIFCH_16
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:49:20
            Original ID  :: gnl|Prokka|JJMKIFCH_16
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 57018
            Orig. end    :: 69169
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7151]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7151
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             62..1456
                     /locus_tag="ctg16_53"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLCLLVLVVGCMTIHQRRHFNKNVKIDNVAVGG
                     LTAKQALKKLQDNPQLPKIYVNNELVFKDKQSVAKFSSADKPKIKNALHSQYTFFPSSK
                     VKNIAVKPQSINQDEVSKIDQAVSQKVTELNNGRKAPVDAYAVYENGRVQIKPAVGGTQ
                     YSLDGLHDKVENEIAGGTVHLKPKYTTPLSANSKTVQNEKAKLEELSKRSVTYQVQNKK
                     YQLNCGEIITRATYQNGKYHFDTGTADSKIDEINNTQATLGKSFEFKTHSGSVIKTTAA
                     GSYGWKISKKQAGKTLTNALVANKQTVNAKNDIYGKGYNQQGTGYNTTSNNGIGDTYAE
                     VSLADQHAWFYKDGKCVLSTDIVSGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVQYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFHDLQKN
                     EPVIIY"
     CDS             1579..1734
                     /locus_tag="ctg16_54"
                     /transl_table=11
                     /translation="MDLEKKKNLVIINLFYVGLVLLYCILHAGPLNLMVFLIMLVAANI
                     TGLLTK"
     CDS             1753..1893
                     /locus_tag="ctg16_55"
                     /transl_table=11
                     /translation="MKTKKKFYKYEIISDIRLRSICGGQQKMILRGIERPWFAILKHRH
                     K"
     CDS             1893..3191
                     /locus_tag="ctg16_56"
                     /transl_table=11
                     /translation="MINLPVFQAFISEVVNLLGITVIYRILIDDFSKKVIIYDLLATLI
                     ITCIPFTIGTLYLVVLVIYLWLYDFIRKTSNIIIDNILAMFVVIIVSSLFDLMVHYIYG
                     WISNRNVAMYGWLIPIGKLSLSIILAILSFYFMRSKKQKLNMDAYYTFRLWKLISLLFI
                     LYICLTIIAEREGVANNYALLLLMVDFTIIIVIGSGVLNFVRSYISAQHQQRLIDNYKA
                     QIASAHKINKQYNEIRRERHDTRNMLLSVQGYIRDHKDKEAEKLLATFLQNDTVEKHYG
                     EIDNALDKIKISGLHNLVKEKAYKIVEKGIPFSFEINAEIDELPGSEIKTARIIGILMD
                     NAIEATFKQAKPYIQFALLKHSAEVYELVIANSIEQKLNINTALKFEHSTKEGHQGIGL
                     SNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             3199..3966
                     /locus_tag="ctg16_57"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEAYLAILDIELDNQLSGIDVAEQIRKKAEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGKQIESIADRLRIDIDEAYARYQNYMNSNQKHQEKFTYEPTHGVKRQVDF
                     ENLYYIESVKNTNRRLRIVGKDIRIEYHGELNQVDSNHLLKVNQSTLINPKAIQEFNRK
                     ERIVYFDTNREIKVTVSYRKIKSLVDFLEKENH"
     CDS             4195..4362
                     /locus_tag="ctg16_58"
                     /transl_table=11
                     /translation="MMKILTTAELEGINGGFKHNIWYYYGWGRASCIGTQRRNPSAFLN
                     HPNFIVLGGN"
     CDS             4364..4522
                     /locus_tag="ctg16_59"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVGDIINSIKKWTQSCYEG
                     YQDSPFH"
     CDS             4564..4725
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_60"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYRKLNFNELSEVSGGWGVTPWSVAWQTGKVAYSLVKHRRSYYA
                     GYQDSPFH"
     CDS             5001..7151
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 323.4; E-value:
                     4.6e-98)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_61"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.1e-38, bitscore:
                     124.9, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 2.1e-274, bitscore:
                     905.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYPHYVAQVDEADCGAAALAMILRNFGSVYPIAKLRDLVRTT
                     KQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFGRLWSGVSLLFSPAKGYTPQKEPLAGLMTMFRQLTNY
                     KKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLAILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLRLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAILVIQDRLSIGTVMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLN
                     EVLQIDTEKSDTNSQDQADLVGPINIQHVDYSYEYSRPILQDINLQIGCNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQSPQLFSGTIKDNL
                     LMGLDREVSIEEIDNACKLALIYNDIQEMPLKYETKLDEEATVLSGGQKQRLTLARALL
                     TSARVLIFDESTSSLDPITEKRIVENLLSIKDRTMIFIAHRLSIAKKVNRVVVMRDGKI
                     IEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7184..7369)
                     /locus_tag="ctg16_62"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYIYLLLLFLWIAPFSDGSLPLDEELLCIFF
                     IIFTISSMLAIMFNKD"
     CDS             complement(7647..8075)
                     /locus_tag="ctg16_63"
                     /transl_table=11
                     /translation="MSKYKVTAAKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             complement(8144..9139)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 299; E-value: 4.6e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_64"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 9.1e-54, bitscore:
                     174.2, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTANV
                     DGLVIQQRSKVPADIYEKLHTNGLKQITTRTAGFDMVDIKKANENGLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSTEIHTATIGIIGVGRIGGTLAKL
                     LHALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPTSKGLLTAKDFAM
                     MKPTAGLVNASRGPVVNTADLVTALKKGTIAAAALDTFEGEETVAATNRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMTILNGEKSPHEITL"
     CDS             complement(9141..10328)
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     6.9e-73. Score: 237.6. Matches aSDomain:
                     nrpspksdomains_ctg16_65_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 276.5; E-value:
                     6.1e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_65"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.2e-72, bitscore:
                     237.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.7e-07,
                     bitscore: 22.9, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATKKEILNRLNNNFAKLTPGGIREFDYQVNTIPGIIKLTLGEP
                     DFNVPAAMKQAAIDSINANDSHYAPGNGTLALRQAIAHFMQDRYQLDYDPENEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGTPIEVDTSGDDFVLTPARLQS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTIKSTNLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGFELINPQGAFYVFVKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIAAFINKED"
     aSDomain        complement(9168..10220)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg16_65_Aminotran_1_2.1"
                     /evalue="6.90E-73"
                     /label="ctg16_65_Aminotran_1_2.1"
                     /locus_tag="ctg16_65"
                     /protein_end="387"
                     /protein_start="36"
                     /score="237.6"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPAAMKQAAIDSINANDSHYAPGNGTLALRQAI
                     AHFMQDRYQLDYDPENEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGTPIEVDTSGDDFVLTPARLQSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTI
                     KSTNLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGF
                     ELINPQGAFYVFVKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             10835..11056
                     /locus_tag="ctg16_66"
                     /transl_table=11
                     /translation="MRIDIKHYLEVNHLTIYQVSKRSGYGYTTLHKSFNKPQSSSTSLN
                     LRDLDALARAQDKSMWEVLKELEEHYLE"
ORIGIN
        1 attaagtgat cattcattat agaaatatac ttaaaggttt ggatgttatt ggagtacttt
       61 tatgcaaaaa ctatctatta aacaactaat aataattacg ttgtgcttat tagtgctggt
      121 ggttggctgc atgactattc accagcgtcg tcattttaat aagaacgtta agatcgataa
      181 tgtggcagtt ggtggattga ctgctaagca agcattaaag aagttacaag ataatccaca
      241 attgccaaaa atttatgtta acaatgaatt agtatttaag gataagcaat cagtagcaaa
      301 gtttagtagt gctgataaac caaaaattaa aaatgcatta catagccaat acactttttt
      361 cccatcatct aaggtaaaga acattgcggt taagcctcaa agcattaatc aagatgaagt
      421 atcaaagatt gatcaagcag tcagtcaaaa ggtaacagaa ttaaataatg gtcgaaaagc
      481 tcccgttgat gcttacgcgg tatacgaaaa tggccgagtg cagataaaac cagcagttgg
      541 tgggactcaa tatagtttgg atggtttgca tgataaagtt gaaaatgaaa ttgctggggg
      601 aacagttcat ctgaagccaa aatatacgac tccactttct gcaaatagta aaactgttca
      661 gaatgaaaaa gcaaagctcg aagaattatc aaaacgatct gtaacatacc aagtacaaaa
      721 caaaaagtat caattaaatt gtggtgagat tattaccaga gcaacctatc aaaatggaaa
      781 ataccacttt gatactggga ctgctgattc aaagattgat gaaattaata atacccaagc
      841 aactcttggc aaatcatttg agttcaaaac tcacagtgga tcagtgatca aaacaacggc
      901 tgctggctcg tacggttgga agatcagtaa aaaacaagct ggaaagactc ttacgaatgc
      961 attggttgca aataagcaaa cagtaaacgc caaaaatgat atctatggta aaggttataa
     1021 tcaacaagga actgggtata atactacaag caacaatggt ataggggaca cttacgccga
     1081 agtttcactg gccgaccaac atgcctggtt ttataaagat ggtaagtgtg ttcttagtac
     1141 tgacattgtt agtgggacca ataacaaaga taatgaaact cctaagggtg tctggtatat
     1201 catgtaccag caaacaccgt ctgttcttcg aggacttaat gatgatggtt cgaaatatgc
     1261 aagtaaagtc cagtattggt ctcctttcac tgatagtgga tgtggatttc atgatgcaag
     1321 ctggcgtcat gactggtcga aacaagccta tctcgctaaa ggtggcggat cgcatggatg
     1381 tatcaacatg catccagatg ttgccggtca agcctttcac gacttacaga aaaatgagcc
     1441 tgtaattatc tactaaagga gaatttatta tgcgcccaag tgctgaacgc tcaataatga
     1501 ttgcggttgt ttgtttcata ttaacaatta ttatttcatt cgccttgtct gagggatgga
     1561 taaagtaggg atttaacgat ggacttagaa aagaagaaaa atttggtaat tattaatctg
     1621 ttttatgtag gattagtttt gttgtattgc attttgcacg caggaccact gaatttaatg
     1681 gtgtttttga taatgctagt tgcagctaat ataacaggat tgttgactaa ataaaaaatg
     1741 ggagaaatag aaatgaaaac aaagaaaaaa ttttataaat atgaaattat ttcagacata
     1801 aggttaagat ctatttgtgg tgggcaacaa aaaatgatat taagaggaat tgagcgccct
     1861 tggtttgcga tattaaagca taggcataag taatgattaa cttacctgtt tttcaagcat
     1921 ttatttctga ggtagttaac ttactaggaa taacagtcat ttatcgtata ttgattgatg
     1981 atttttcaaa aaaagttatt atttatgatt tattagcaac tttaattatt acttgtattc
     2041 cttttacaat cggaaccctc tatttagtgg ttttagtaat atatctatgg ttatacgatt
     2101 ttataagaaa aacttctaac attattattg ataatatctt agcaatgttt gttgttatta
     2161 tagtttcttc attatttgat ttaatggtcc attatattta tggttggatt tcaaaccgta
     2221 atgtggcaat gtatggatgg ctaatcccta taggtaaact tagtttatct ataatattgg
     2281 ccatattatc attttatttt atgcgctcta aaaaacaaaa attaaacatg gatgcttatt
     2341 atacttttcg tttatggaaa ctaataagtt tactttttat attatatatt tgtttaacta
     2401 ttattgctga aagagaagga gttgctaata attatgcgct tttactttta atggtagatt
     2461 ttactattat tatagttatt ggtagtgggg tacttaattt tgttaggagc tatataagtg
     2521 ctcagcatca acaacgactt attgataact ataaggcaca aattgctagt gcccacaaaa
     2581 taaataaaca atacaatgaa attcggcgtg aacgtcacga tacacgtaat atgcttctca
     2641 gtgttcaagg atatattcgt gatcacaaag ataaggaagc ggagaaatta ctagcaacgt
     2701 ttcttcaaaa tgatacagtt gaaaagcatt atggtgaaat tgataatgca ttagataaga
     2761 ttaaaatctc tggcttgcat aatcttgtta aggaaaaggc ttataaaata gtagaaaagg
     2821 gtattccgtt ttcgtttgaa attaatgctg agatcgacga gttgccgggt tcagaaataa
     2881 aaactgctag aattatcgga attttaatgg ataatgcaat tgaagcaaca tttaagcaag
     2941 ctaaaccata tatccagttt gcattgctta agcatagtgc agaagtttat gaattggtaa
     3001 ttgctaattc aattgagcaa aaacttaata ttaatactgc actaaaattt gaacattcga
     3061 ctaaggaagg gcatcaagga attggccttt caaatgtgac acagttggta gaaaatgatg
     3121 accattattc tttttcagcg gaagttaaag ataaggtaat tatgatgact tgttttattc
     3181 agggaaagtg agaataaaat gttaaaagta attattttgg aaaatgatga ttatcaagct
     3241 gattatactg agcgtctagt ttctcagcga aagttgatta acgctactcc aaatagttat
     3301 gacatagaat tatatttgcg gacaaatgat ccgcaagaag tgattgatag catcaaagat
     3361 gaggcttatt tggcgatttt agacattgag ctagacaatc aacttagcgg gattgacgtt
     3421 gctgagcaga tccgcaaaaa agctgaattt gccgaaatta tctttgtaac tgcttatcaa
     3481 gaatatttac cttatactgt ttcgcgccga attgagccat ttgattatat atcaaagggt
     3541 aagcagattg agtcaattgc ggatcgtctc cggattgata ttgatgaagc gtatgctcgc
     3601 tatcagaatt acatgaatag taatcaaaaa catcaagaaa agtttactta tgaaccgact
     3661 catggagtaa aaaggcaagt tgattttgaa aatctctatt atattgaatc agtaaaaaac
     3721 acaaatcgac ggttacggat cgttggaaag gatattcgaa ttgagtacca tggtgaacta
     3781 aatcaagttg atagtaacca tctattgaaa gttaatcaga gtacgctgat taatcctaaa
     3841 gcaatccaag aatttaatcg taaagaacgt atagtttact ttgatacgaa tcgagaaatt
     3901 aaagtgactg ttagttatcg aaaaataaaa tcattagtcg attttctcga aaaggaaaac
     3961 cactaactac tttattttca aagaaactgt gacaaaaaaa gctgtcatag tttctttttt
     4021 attatcaagt aattttagta aacgttttca aaatttttac tacgaattat gcagaaaggt
     4081 ttacgaattt tacaaaatac tcccaaaatg cttttttgcc tatatactaa tagtgtaatc
     4141 aaggtaggga aaaacttgat ttattaaaat taataattac gaggaggagt aattatgatg
     4201 aaaattctta ctactgctga acttgaggga atcaatggtg gatttaagca taacatttgg
     4261 tactactatg gttggggaag agcatcatgc attggaacac aacgtcgcaa ccctagtgca
     4321 ttcttaaatc atcctaactt catcgtatta ggaggtaatt aaaatgactt accgtaaatt
     4381 gaactttgat gaattaagca aagtttctgg tggatggagc ttatcttcgc aggttaatga
     4441 actagttgga gacattatta attctataaa gaaatggact caatcttgtt atgaaggtta
     4501 ccaagatagt ccgtttcatt aggaataata aaggatagtt attttgagat ggaggtaatt
     4561 aaaatgactt accgtaaatt gaactttaat gaattaagcg aagtttctgg tggatgggga
     4621 gttactcctt ggagtgttgc gtggcaaaca ggaaaagttg cttattcgct tgttaaacat
     4681 cggcgttcgt attatgcggg ctatcaggat agtccatttc actaatagtt tataacttaa
     4741 tgattatgaa atttaaccac gatttttaca ccaatcttga tttttatatc tatattatag
     4801 ttacattctt ctgggtctta gcaattccca aggcaagtaa catttatgaa acaattatat
     4861 gtatagcttg cacaatcatt ggtatttttg cagctctacg aattttattt aaaaataaat
     4921 agtatcttat aagaatataa agcccagaat cattattaat tttggacttt atttctttgt
     4981 ctgattagaa agcaaggtga atgaaaatca attatcctca ttatgtagct caagttgatg
     5041 aagcagattg tggagccgct gctttagcaa tgattttgcg caattttggg tctgtttatc
     5101 caatcgcaaa attacgtgac ctagtccgga cgactaagca aggaactact gccttaggac
     5161 ttgtaaaagc agcgaagcat cttggattag acgttatacc cattcaagca gatatatcat
     5221 tgtttgatga tcctgaaatt acttacccgt tgatcgcgca tgtgattaag gatgatttac
     5281 ttcattactg tgttgtcttt aaggctgatc aagattacat ctatgtagct gatccagatc
     5341 ctgctacgaa agtacaaaaa atgacgcggg atgaatttgg tcgtttatgg tcaggtgtaa
     5401 gtttactttt ttcgcctgct aagggatata cgccacaaaa agaaccttta gctggattaa
     5461 tgacgatgtt tcgacaatta actaattata aaaaagatat atcaggaatt gtcattgcgg
     5521 caatgttaat tactttcatc agcatcgtcg gttcatacta tctccaatta attattgatc
     5581 ggtttattcc ctcgaaaaat attaatggct tagcgatcct tgctggtagt ttattagtag
     5641 tttatgtgtt taattctctt tttaattatc tgcgagatgt tcttttgact aggctggatc
     5701 aaaaactgac atcacaaata agtctgcgat atattcacca tgtttatcgt ctaccgatgc
     5761 gatttttctc cacaagaaaa acgggagaaa ttacttcacg gtttaatgac attaataaga
     5821 ttattgatgc cttatcaagc actattattt caatgttctt agacgttggc gtgatggtga
     5881 ttataggaat tgttctttct ttatatgatc ggtcattatt tttaactaca attagtacca
     5941 ttccaattta tgtcattatc atttatgcct ttaataagcg ctttgctaaa cttgatcagg
     6001 aacagatgga aagtaatgct caattaagct ctgctattat tgaggattta aaaggcgtag
     6061 agacgttgaa agtactgcga cttgaaaata tccgttataa aaatgttgaa aaacaatttg
     6121 cggatttctt acgaaagaat ctaacatatg ttaaaactaa atcttttcag gatgcaatta
     6181 aaatgtggat tcaatacggc ttagtaacaa tcattctttt tcaaggggca attttggtaa
     6241 ttcaggaccg attaagtatt gggaccgtga tggcttttaa tgcgttatta gccttttttg
     6301 tcagtccatt gcaaaatatt attaatcttc aacctaaact ccaagaagct aaagtagcga
     6361 ataatcgatt gaatgaggtg ctgcaaattg acaccgaaaa gtcagatacg aattctcagg
     6421 atcaagcaga tttggtaggg ccgataaaca ttcaacatgt tgactattca tatgaatata
     6481 gtcgtccaat tttacaagat atcaatcttc aaattggttg taatgacaaa ttggcaattg
     6541 tagggttgag cggttctggt aaatcgacct tggcaaagtt gttagttggc ttttatttac
     6601 ctactcaagg gcagatagaa tttaatcagc ataaaacaac agagattaat ctttgcgata
     6661 ttagacaata tgtacattac ttaccccaat cgccacaatt attttcggga acaatcaaag
     6721 ataacttgct aatgggatta gaccgtgaag tatctattga agaaatcgat aatgcatgta
     6781 aattggcatt aatctataac gatattcaag agatgccctt aaaatatgaa acaaaactag
     6841 atgaagaagc aaccgtatta tctggtggtc aaaaacaacg cttgacgctt gcacgagcac
     6901 tcctaacttc tgcgcgtgtt ttaatttttg atgaatcaac aagtagctta gatccaatta
     6961 ctgaaaaaag aatcgttgaa aatttgctta gtattaaaga ccgcacaatg atttttattg
     7021 cccaccgcct ttcaattgcc aaaaaggtca atagagtggt agtaatgcgc gacggaaaaa
     7081 tcattgagca gggtactcac caggaacttt tgaatcatca tcaagaatac tataatttgt
     7141 ggaatgcata aaaggctccg aacattgctg ttggagcctt ttttcagtct ttattaaaca
     7201 taattgcgag catggaactg atagtaaaaa ttataaagaa gatacatagt agctcctcat
     7261 ctaatggaag cgaaccatct gaaaatggag caatccagag aaacaaaagt aataagtata
     7321 tataaaagaa accatcccgc caaaagtcct tattgaaatg aattttcatt agttctcccc
     7381 ctaagacagt atgtgtacct tattataatg aaagatctaa tttaaaggac attttgcaaa
     7441 attcgttaag tttcttgcag aattcgtata ggttaactat ttagaaaggg actgtgacat
     7501 aagcgaagtt actttcataa aaaaacaaat ggcgcagtac accaatggcc tccaacgccc
     7561 ggtaaaaccg aatgttggag gcctattgtt gcttgcgggg ctcgaaaacg aagtcacgag
     7621 tgacttctgt ctcgctccct tttcaactaa tcaactttta caaatccatc ttgaacaaat
     7681 tttgttccgt aggtcagagt gttttccacg ggacactttg cggcaacgtc agcgaggaac
     7741 ttcttaatgt cttcatcaga ctcgctgctg cgaagatgtg gttggtaacg gatctcagta
     7801 aacttacgaa cattcttacc atcagcaaca tcttcacgac caagatcacc ctcgattgtt
     7861 acccaaaaag ctcgtaaatc aaagttacgc tttttagcta atgcttgggc agtgattgcc
     7921 tgacaggcac caaatgatgc aaggagaatt tctactggat tcatccccgt atttgtactt
     7981 tctggttcat caaatgtaat ttcaaaacca cgggtacctg ctgaaacttg catccccgtt
     8041 gttgtcttag ctgctgttac tttatattta ctcatagccg ttccctcctt ttaataccca
     8101 tagtgtaatc gagacgatac ttttggtcaa tgagggtgct caattataag gtaatttcat
     8161 gtggtgattt ttcgccatta aggattgtca tcacatcatc aagtgaaata tccaccatgt
     8221 ttttgactgc taaattagta aagaaggcaa tgtggggagt aagaatgaca ttatccattt
     8281 cgtgtaattc tttaacaagc ggctgatcgt caagtccttt ttctcggcga tttgtggccg
     8341 ccaccgtttc ttcaccttca aaagtgtcaa gagctgctgc tgcaattgtt ccttttttaa
     8401 gggctgtaac taaatcagct gtattaacga ctggaccacg gctagcattg accaaaccag
     8461 cagttggttt catcattgca aagtctttag cagtcaacaa tcctttggaa gttgggttta
     8521 aatcgacgtg gagactaaca acatcggctt gctttagtaa ttcttcttta gaaacgaact
     8581 ggacaattcc atcgaggtca gtgcgcggat tcgtgtcata accaagaaca gtggcgccta
     8641 atgcatgaag aagctttgcc agggttccgc caatgcgtcc aacaccaata atcccaatcg
     8701 tggcagtatg aatttccgtt gattgttcat cgctaaacca gcggaaatca ttttcagcga
     8761 cttggtggtc aaagcggtaa gttttccgaa gcaaccggaa aatctgcatt aatgcaaact
     8821 cggcgacact ccgcggtgaa tatgctggta cattggtcac gactaagcca ttttcgttag
     8881 cctttttgat gtcgaccatg tcaaatcccg cggtccgcgt tgtaatctgt ttgagcccat
     8941 tggtatgtag cttttcataa atatcagccg gaactttact acgttgctga atcacgagtc
     9001 catcaacatt ggccgttaat tcaacagcat cgtcaatcaa tttcggcgtt gtgatgattt
     9061 cgatattatg ttctttcgcg tattcgttaa tggcggtttg ttcatcgtcc cgcacactag
     9121 tcatcaagat tttcgtcatg ttaatcctcc ttattaatga aggccgcaat gttatcaaga
     9181 gctccggtta gattttccat actggtggcg taactaattc gaacatatcc ttggccgcca
     9241 gctccaaaga aggaaccagg aatcacagca acttttcctt cattagcaag atctgtcgca
     9301 aatttaagat catcattacc atattgttca ggaatcttaa caaaaacgta gaaggctcct
     9361 tgaggattaa tcagctcgaa ccctaatttt tggaggttat taacaacaaa gtctcgtcgt
     9421 tgctcataag catctttcat ttcttgagta gctgtttttc cttcgtcagt accaaatgcg
     9481 gcgactgcag cggccattgc tggattagaa gcagcggtca ctaacatcgc gtgaatggca
     9541 ctgaccgatt tcatcaattc ttgcggccca gcgataaaac caatgcggta accagtcatt
     9601 gcatgtgact ttgaggcacc atttaaaatt agcgtttgtt cggggatgta attagcgatt
     9661 gaagtatgag tagctccgta aaccagttca gagtaaattt catctgcaat tacaatcagg
     9721 ttagttgatt taatcgtatc ggctagtgct ttaatttgat cttgggtgta agtaacacca
     9781 gttgggttgg agggatagtt aagaactagt ccctttgcat taggatgttc ttctagtacg
     9841 ctttggagtc ttgcgggtgt gagaacaaaa tcatcgccgc ttgtatcaac ttcaatcggg
     9901 gtcccaccaa gaatctttgt gacagccatg tagaagggga aagttggggt tggaatgata
     9961 atttcatcgc caggattaat aatagtcgaa agagaagcga aaattccttc tgttgcgcca
    10021 actgtaacag caatttcgtt ttctggatcg tagtcaagct ggtaacgatc ttgcatgaag
    10081 tgagcgattg cttgacgaag tgctaaggtc ccgtttcccg gagcatagtg tgaatcattg
    10141 gcattgatgc tatcgattgc ggcctgcttc atcgcggctg gcacattaaa gtctggttca
    10201 cctaatgtta gtttaatgat gccagggatt gtgttgactt gatagtcaaa ttcgcggatc
    10261 ccgccaggag ttagtttagc gaaattattg ttaagacgat taaggatttc ttttttagta
    10321 gctggcatga taaattcctc ctatataata tgtagattta gaaataaaag aagccctgaa
    10381 tgctatagga ataacatcca gggcttcttg atcagattgg aatgagtata aaagaggctc
    10441 tcggatgttt gggggtcatc cgggaacatc acaatgataa aatcactgct ggttagcgga
    10501 cggtaatcgc gctaaaccag aagacatacg cttgattcaa gtgaattgtc gcagtgctca
    10561 tcattgtgtc ctccttttga ttaactgatt attaattatt ctaattattt tttaatcttt
    10621 gtcaagggtt gattgagaaa aattattaat tacaaaatta tttattgatg acaaatgtaa
    10681 atataatgaa atacaaaaat atttgtgatt attagttcgc ctttaattta atattaaaat
    10741 tatattctac aatttttttt attttttcgt gtcttttttg ttgtcttact ccacaaatgt
    10801 gatataatat taatcgtaaa ggaagtgggt agcaatgcgg atcgacatca aacattattt
    10861 ggaagttaac cacttgacca tttatcaagt ttccaagcgt tccggttacg gctacacgac
    10921 tttacacaaa tcgtttaaca aaccacagtc tagttcgacc tcgcttaacc tgcgtgacct
    10981 tgatgccttg gctcgcgctc aagacaagag catgtgggag gtccttaaag aactagaaga
    11041 gcattacctc gaatgagatt gtggcattgc tgtagccaca ggaggtcaaa tgcattaact
    11101 tttgacttct agaatactta gactacgaaa cttagaaaac aaaatattat atttaattga
    11161 ggagggattg catatggctc aaaacccaat taatccattt gacaacgaca tgaatgacat
    11221 ctttaatcaa ttaatgggtg gcatgaatgg tttcaattct gataatcggc gttacctaat
    11281 caatggtcgt gaagtaacac cagaagaatt tgctgaatat cgtagaactg gtcaattgcc
    11341 tggcggtgca aatcctcaac aaggtcaacc aggccctcaa cctaatgaag gtaaggacag
    11401 tatcttacac aaattaggtc gtaatttaac agaagaagct cggcaacatg aacttgatcc
    11461 agttatcggg cggaacaaag aaattcaaga aactgctgaa atcttaagcc gtcgtactaa
    11521 gaataaccct gtattagtcg gggatgctgg tgttggtaag acagctgttg ttgaaggatt
    11581 agcccaagca attgtttccg gtgatgtacc agctgcaatc aaggacaagg aaattattag
    11641 cattgatatt tctggccttg aagcaggtac tcaataccgt ggtagctttg aagaaaatat
    11701 gcaaaagttg gttgatgaag tcaagaaagc tgggaatatc atcctcttct tcgacgaaat
    11761 tcaccaaatt atcggtgccg gttcaactgg tgattctagt ggttccaagg gtatgtctga
    11821 cattattaag ccagcattat cccgtggtga actaacagtt atcggtgcaa ctactcaaga
    11881 tgaataccgg aatactatta tgaaggatgc tgcattagca cggcggttca attctgttac
    11941 tgttaatgct ccaagcaagg ctgatacagt ggccatcctt aaaggtattc gtgacttgta
    12001 cgaacgtcac cacaatgtaa agttaccaga tgacgttctc caagctgctg ttgattactc
    12061 tgttcaatac atgccacaac gtgcattacc tgacaaggct atcgacttaa tcgatatgac
    12121 cgctgctcac ttagcagcaa agcacccagc a
//
