LOCUS       gnlProkkaBLFJPDAG_4    20270 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BLFJPDAG_4.
ACCESSION   gnlProkkaBLFJPDAG_4
VERSION     gnlProkkaBLFJPDAG_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:46:28
            Original ID  :: gnl|Prokka|BLFJPDAG_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 670185
            Orig. end    :: 690455
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20270
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10270]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10270
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20270
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20270
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="4"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(1398..3278)
                     /locus_tag="ctg4_660"
                     /transl_table=11
                     /translation="MAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFVPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKFIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEESKYKDLFEEMK
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     CDS             complement(3446..3697)
                     /locus_tag="ctg4_661"
                     /transl_table=11
                     /translation="MKVQHKKELKFYCIVTIPSAFVVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG"
     CDS             3814..4635
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 2.6e-09. Score:
                     29.1. Matches aSDomain: nrpspksdomains_ctg4_662_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     247.9; E-value: 1.8e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_662"
                     /sec_met_domain="adh_short (E-value: 2.6e-32, bitscore:
                     107.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.2e-36, bitscore:
                     122.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEE
                     TVDAIRKNGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTKAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEQFREANKWITPLGRLG
                     QPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIEEKWKEETK"
     aSDomain        3835..4293
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_662_PKS_KR.1"
                     /evalue="2.60E-09"
                     /label="ctg4_662_PKS_KR.1"
                     /locus_tag="ctg4_662"
                     /protein_end="160"
                     /protein_start="7"
                     /score="29.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRK
                     NGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       3841..3918
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_662_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg4_662"
                     /protein_end="35"
                     /protein_start="9"
                     /score="17.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARVII"
     CDS             complement(4664..5806)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 40.3; E-value: 7.3e-12)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_663"
                     /transl_table=11
                     /translation="MPESAEAQVKEALLALLKDRDIQHITMKEIAEKAKVSRGSLYLYY
                     EDKFSIIEDVIEDMKEGLGKALFDAFSHMDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFKDVFQQDVLLAPIHVNLTPIERDIYGHYRALYTYAIILYWLNEDAAASPE
                     AISQKVWELVSQKRFYWLFGKAVPGEREKEKQIDRRVVRTREALQKAFLDVLAEKQDYA
                     GITISDITRKSNIRRATFYDHYANKEELLQTMIQRSCAEIIDHLTIASSPNEFSLKEAE
                     KALAILLSALSNMPIVHFLNREWGVPHVIPDMFKALESFYLHQQTDIHAEKKLYAHYVS
                     AMIIGLLLYRLDEGKAHPPEVLAREFLQFLDVKKYKVVLL"
     CDS             5949..7286
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 299.5; E-value:
                     5.6e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_664"
                     /sec_met_domain="Aldedh (E-value: 4.9e-99, bitscore: 327.5,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQQVKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDH
                     TPDRSKFTQIVNDRNFNRVKDLFDDAIERGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFASILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQAAE"
     CDS             complement(7325..7804)
                     /locus_tag="ctg4_665"
                     /transl_table=11
                     /translation="MNIIPTCQIPKDLVSAFFQKHWGSPQMVISSGIYNCDELDGYGML
                     NDDNQIVGLITYIFEEDACEIISLDSVIENKGIGTALLEKAEEACRERNIKQIKLITTN
                     DNIHALAFYQKRGYRLDRLFVNAVETARKMKPEIPLLADNKIPIRDELLLVKELQ"
     CDS             complement(7884..8876)
                     /locus_tag="ctg4_666"
                     /transl_table=11
                     /translation="MSAVTESVLESIISPVTMSEFLEEYWPVKPLVARGEVERFTSIPG
                     FEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTD
                     LFIPQVRRWIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWK
                     LAKNENVSNPMQHYDLSEAPYYPDDLQSYWKGDPPKEDLPDAEIVNLTPGTMLYLPRGL
                     WHSTKSDQATLALNITFGQPAWLDLMLAALRKKLISDNRFRELAVNHQSLHESSKSELN
                     GYLESLIQTLSENAETLTPEQIFQSQDSDFDPYQSTQLVFRQLLTSYKF"
     CDS             9267..10001
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 103.3; E-value:
                     2.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_667"
                     /transl_table=11
                     /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMGT
                     GPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYADQY
                     ADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVILDTFNPQGSHLEIMRKQIKEPEYF
                     RFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQNDQS
                     TDHEIESVTWMLTIEKEKEGAL"
     CDS             10001..10270
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_668"
                     /sec_met_domain="PqqD_RRE (E-value: 1.1e-08, bitscore:
                     30.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.1e-11, bitscore: 40.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.1e-08,
                     bitscore: 30.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDGK
                     VSIHDICSKIVNEYDVDYQTCLEDCMELFELLIDHEAIKVKQGA"
     CDS             10274..10756
                     /locus_tag="ctg4_669"
                     /transl_table=11
                     /translation="MEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDI
                     VSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHT
                     WYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ"
     CDS             10777..13020
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 407.1; E-value: 2.2e-123)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_670"
                     /sec_met_domain="GATase_7 (E-value: 6.4e-44, bitscore:
                     144.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.7e-94, bitscore:
                     312.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSK
                     VGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVI
                     VHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIK
                     SLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNER
                     KTASYWSLQDILLRQGYRENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSA
                     AVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPES
                     YKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAEN
                     PSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVL
                     TKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKS
                     LTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEH
                     IHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETPSVQLDITSHLESITIKDWHSQE
                     GDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFIQFIVSEEDVGAW
                     LHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR"
     CDS             13017..14216
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 97.4; E-value: 1.1e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_671"
                     /transl_table=11
                     /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEI
                     AKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLI
                     SGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYL
                     LLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFTATAY
                     DTISRYWQPFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRFEKKIEKNPYLALTSLDS
                     MGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFSLNSGVG
                     AIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQIEKSQQV
                     "
     CDS             complement(14280..15512)
                     /locus_tag="ctg4_672"
                     /transl_table=11
                     /translation="MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVLQPTAAYAAETV
                     FSQNNGASGFLPGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGAVI
                     DGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFI
                     DKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKLKTNG
                     VVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGNIYAGN
                     QDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGDMNWSFY
                     TDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQLAEDGTLYI
                     GSYTKLMAFGK"
     CDS             complement(15613..16038)
                     /locus_tag="ctg4_673"
                     /transl_table=11
                     /translation="MSKKNSVAIMTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAGM
                     WSAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLS
                     EVIFVLGVSLAAAAVNVIWFVAAFRSGAEKTSVNTLT"
     CDS             16295..16750
                     /locus_tag="ctg4_674"
                     /transl_table=11
                     /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFIINSVFVAGAVATNP
                     YMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGER
                     VSVGQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK"
     CDS             complement(16780..17988)
                     /locus_tag="ctg4_675"
                     /transl_table=11
                     /translation="MSSLQPTLTNERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSML
                     GKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVPLY
                     VRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLFSIP
                     FMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGMLTYNP
                     LNYFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYSVTDK
                     EICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYH
                     YGLGLYGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLSWQPIAKK
                     TKV"
     CDS             complement(18096..19109)
                     /locus_tag="ctg4_676"
                     /transl_table=11
                     /translation="MKTLCTHSLPKEKMPYLLRSGEGERYLFGRQVATVMANGRSTGDL
                     FEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPAGTPHS
                     YRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVSNERFAEAAAVADIVF
                     LDEAKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRIVAAQKNTDGQFIVVS
                     SEGPKGDRIVDHYHEYHTETFYCLEGQMTMWTDGQEIQLNPGDFLHVPANTVHSYRLDS
                     HYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALRFDRILQNIEALDLKVMKP"
     CDS             complement(19203..19778)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 63.1; E-value: 7.5e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_677"
                     /transl_table=11
                     /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYH
                     FFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPVEAIQLFIKKTASQFDNTESIKGI
                     PVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMIEGG
                     IMLSLTNKDKTPLLLIAEQIPVLVRKKG"
ORIGIN
        1 tactttttcg gcgctttagg gggactgcta tatggttacg atacaggtgt tatctccgga
       61 gcactcctgt ttatcaataa cgatattcct ttaacgacat tgacagaagg attggttgtc
      121 agcatgctgc tccttggcgc gattttcggt tctgccttga gcggcacatg ctcagaccgc
      181 tggggcagga gaaaggttgt atttgtcctt tccatcattt ttattatcgg tgcgctcgct
      241 tgcgcatttt ctcaaacaat cggcatgctg attgcatcta gggtgatact cgggttggcc
      301 gtcggcggtt caacggcact tgtgcccgtg tatctttccg aaatggcacc gacgaaaatt
      361 cgcgggacac tcggcacaat gaacaactta atgattgtca ccgggatttt gctcgcctat
      421 atcgttaact acctgttcac accgtttgaa gcgtggcgct ggatggtcgg tctggctgca
      481 gtgcctgccg tgcttctatt aatcggcatc gccttcatgc cggaatcgcc aagatggctc
      541 gtgaagcgcg gcagcgaaga agaagcgaga cgcatcatga acatcactca tgaccccaaa
      601 gacatcgaaa tggaattggc agagatgaag caaggggaag cggagaaaaa agaaacgaca
      661 cttggcgtgc tgaaagccaa gtggattcgc cctatgcttc tgattggcgt cggccttgcc
      721 attttccagc aggcagtcgg cattaacacg gtcatctact acgcgccaac catttttacg
      781 aaggccggtc ttggcacatc agcttcggcg ctcggcacaa tgggaatcgg catcctcaac
      841 gtcatcatgt gtatcactgc catgatctta attgaccgtg tcggccgcaa aaaacttctg
      901 atctggggaa gtgtcggcat cacactgagc cttgctgctt tatcaggcgt gctcctgaca
      961 ctggggcttt ccgcatcaac agcgtggatg acagtagtct ttctcggtgt ctatatcgtc
     1021 ttttaccagg cgacatgggg tccggtagtg tgggtgctca tgcctgagct cttcccgtcc
     1081 aaagcacgcg gagccgcgac agggttcacg actttggtgt tatcggcggc taacctgatc
     1141 gtgtcgcttg tcttcccgct gatgctaagc gcgatgggca tcgcatgggt ctttatggtt
     1201 ttctcagtca tttgtcttct ctcatttttc ttcgcgttct acatggtacc ggaaaccaaa
     1261 gggaaaagct tggaggaaat tgaagcaagc ctgaaaaaac ggtttaaaaa gaagaaaagc
     1321 acccaaaacc aagtgctgaa tgagcgtaca ttataaaaaa aggaatcgtc tccttatgag
     1381 acgattcctt tttctgttta caccatgacc ttgcaaatat tgttcgtaaa ttccacaggg
     1441 tcctgaatcg gcaggccttc gatgaggagc gcctgattgt acagaaggtt tgtgtacagg
     1501 ctcagcttct ctttatcttg ttcaaacgcg tcctgcagtg tttggaatac ctcgtgattt
     1561 gggttgattt ccagcacttt ttccgccttc acattttggc tgtcaggcat cgcatttaag
     1621 attttttcca tctcaattgt cacttcgccg tcagcagcaa ggcagactgg atgtgattta
     1681 agccgttttg agattctgac gtttttcact ttgtctgaca gaatgttttt catttcctca
     1741 aacagatcct tatacttgct ttcctcttcc tcggactgct tttgatcctc atccgtgtct
     1801 atgccaaggt ctccgcttga tacggacttg aattcttttt cctgataaga agccagcatt
     1861 ttaattgcaa actcatcgat gtcctcagta aagtagagga tttcatagcc tttgtccgcc
     1921 accatttccg tttgcggcag tttctcaatg cggtcgtaag aatcaccggt cgcgtaataa
     1981 atgaatttct gctcctctgg cattctggaa acatactcgt ctaagctgac cagttttttc
     2041 tcttttgaag agtagaataa gaggagatcc ttcaattgat ccttattcgc gccaaaatca
     2101 ttgtacacgc cgaatttcag ctgtctgccg aacgacttgt agaacgtctc gtatttctcg
     2161 cggtcttttt tcaacaggct ttgcagctcg cttttgattt tcttgctgat gtttttcgcg
     2221 atcagcttca gctggcggtc atgctgcagc atttctctgg aaatattcag cgacagatcc
     2281 tcagaatcga ccatgccctt cacaaagctg aagtggtccg gtagcaggtc tgcgcactta
     2341 ttcatgatca gcacgccatt ggaatacagc tccaagcctt tctcatattc cttggaatag
     2401 tagtcaaacg gcatgttttc agggacgaat agaatcgcgt tgtagcgaac cgctccatcc
     2461 acgctgatat gaacgtgtgt cagcggttta tcaaacccgt aatgcttttc agcatagaat
     2521 ttttcataat cctcatctgt cagctcgctt ttgttttttc tccagatcgg caccatgctg
     2581 ttgaccgtct gctcttcctg cacctcttca aattcatttt cgctgccttc cttcggctta
     2641 ttaatggttg tatccatttt gatcgggtag cgaatgaagt cggagtactt cttgatgatc
     2701 gcttttaaac gatattcctc taaaaactcg tcatagctgt catcttctgt gttctctttg
     2761 attttcagga taatgtctgt accgacagaa tccttttcac acggctcaat cgtatagccg
     2821 tctgcacccg cagactccca tttataagcc tcttcgctgc caagcgcttt actgatgact
     2881 gtcacgacat cggcaaccat aaatgccgcg taaaaaccga caccgaactg cccgataatg
     2941 tcatgtccgt ctttcagctc gttttccttt ttaaacgcga gggaaccgct ttttgcaatt
     3001 gttccaagat gctgttcaag ctcatccttt gtcattccga tccccgtatc agagatggtt
     3061 aatgttctcg catctttgtc agctgcgacc tttatgtagt aactgtcttt atcaaacgta
     3121 agcgcatcgt ccgtaagcgc tttgtaatag attttgtcaa tcgcatcact cgaattggag
     3181 attaactcgc gcaggaaaat ttctttttgg gtataaatgg agttaatcat catatccagc
     3241 aagcgtttag actctgcttt aaactctttt ttcgccactc ttgatcgctc ctttaccatt
     3301 atgtaaaccc ttttcagcat ctatttatca cataagatga caattgtcaa ttagattgat
     3361 agatgcatat atatgtaaat ttaacattag ttggatttgt tttcactctt tttctcactc
     3421 attctcataa aaaagagagg cttcatcatc ctctcttttt ttctgtgtca ttccaacggc
     3481 caaactcccg cttcatccat atatgcaccg ggtagaaaaa caaaccgaac ggtatcaaaa
     3541 acaaaagatt atgccatgaa gcattcagaa atgcgcttgc agtcaccggg aacgtaatct
     3601 cttgcaataa aaaagagatg acagtcagca caacaaatgc agatggaatg gtcacgatgc
     3661 aataaaactt gagctccttc ttatgctgta ccttcaaaca tacaaacctc ccaacaattt
     3721 ctaattcatc ttaacatatg ctggcctttc ttttctcgca tgtttatcac tgcacatagc
     3781 gggaagacaa atagaaaaag gaggtctcgt atcatgggaa gacttgaaaa caaaacagca
     3841 gttatcacag gcgccgcgac aggcattggt caagcgacgg cggaggtttt tgccaatgaa
     3901 ggcgcgcgtg tgatcatcgg agatatcaat aaagatcaaa tggaagaaac agttgacgca
     3961 atcagaaaaa acggaggaca ggccgaatcc tttcacctcg atgtgtcaga tgaaaacagt
     4021 gtgaaagcat ttgctgatca aatcaaggat gcatgcggaa cgattgatat tctgtttaat
     4081 aatgccggcg ttgatcagga aggcggaaag gtgcacgaat atccggttga cctgtttgac
     4141 cgcattatcg ccgtcgacct gcgcggcaca ttcctttgca gcaaatattt gattccgctc
     4201 atgctcgaaa atggaggctc catcatcaac acctcctcca tgtcaggccg tgccgcggac
     4261 cttgaccgct ccggctacaa cgccgcaaaa ggcggtatca ccaacctgac aaaggcaatg
     4321 gcaatcgact acgcacgaaa cggcatccgc gtcaattcca tttcaccggg cacgatcgaa
     4381 acaccgctga ttgacaaatt agcaggcaca aaagaacagg aaatgggcga acaattccgc
     4441 gaagccaaca aatggatcac gccgctcgga cgtcttggcc agcccaaaga aatggcaaca
     4501 gtggcactgt tcctcgcatc agacgacagc tcatacgtca caggagaaga catcaccgca
     4561 gacggcggca tcatggcgta cacatggcct gggaagatgc tgattgagga gaaatggaag
     4621 gaagaaacga aataagagag ggagccccct ctctttttgt cttttaaagc aatacaacct
     4681 tatatttctt cacatccaaa aactgcaaaa actccctcgc cagcacttca ggcggatgcg
     4741 cctttccttc atccagccga tacaaaagca acccgataat cattgcggat acataatggg
     4801 cataaagctt tttctctgcg tgaatatcag tttgctgatg cagataaaac gattccagcg
     4861 ctttgaacat atcaggtatc acatgaggaa caccccattc ccgattgaga aaatggacaa
     4921 tgggcatgtt tgacaaagca gaaagcagaa tggcgagcgc cttctccgct tcctttaagg
     4981 aaaattcatt cgggctggag gcaatcgtca ggtgatcaat gatctccgca catgatcgct
     5041 gtatcatggt ttggagcaat tcctccttat tggcatagtg atcataaaag gttgcacggc
     5101 ggatattgct tttacgcgta atatctgaaa tcgtgatgcc cgcgtagtct tgtttctccg
     5161 ccaatacatc cagaaatgcc ttctgcagcg cctctctcgt tcgaaccacc cgcctgtcga
     5221 tttgcttctc cttctctcgc tctcctggca cagcttttcc aaacagccaa taaaaccgct
     5281 tttgagaaac aagctcccat accttctggc tgatggcttc aggagacgcg gccgcatcct
     5341 cattcagcca atacaggata atcgcgtacg tgtacaaggc ccgataatgt ccataaatgt
     5401 cccgttcaat cggcgttaaa ttcacatgga tcggagccag cagcacatcc tgctgaaaca
     5461 catccttaaa aaaacgatga aaatgtcctc tgttcatcat cacagaaaaa aaggaacgat
     5521 gctcatgaac aaaggacagc gtcggatgca ccgtttgccg ttttttgttc aaatgaaggg
     5581 tatccatatg actgaaggcg tcaaaaagcg ctttgcccag tccttccttc atgtcttcga
     5641 tcacatcctc aatgattgaa aacttatcct cataataaag gtagagcgat ccgcggctca
     5701 ctttggcctt ctcagcgatt tctttcattg tgatgtgttg aatatctcta tctttcaata
     5761 aagccagcag cgcctctttc acttgagctt cggcagattc cggcacaaaa gacacctcca
     5821 atcattagac agatcttaga tatatgtacg gtaacgtata gatggttcac cgttgtcttt
     5881 cttacagaaa aggtaccacc ttataatagg tccgagaaaa gaagaaagca aatgaggggg
     5941 attttacaat ggaacagcaa gtaaaggacg acatccagcg tgtctttcag cttcagaaaa
     6001 aacagcaaaa agccttgcgc gcttcaacag cggaacagcg gagagaaaag cttcaacgct
     6061 ttttagattc cgtcatcgcc catgaagaag aaatcatcga agcgatccgc aaagacgtcc
     6121 gcaaaccata tcacgaagtc aaaaaagcgg aaatcgaagg aacaaaaaaa gcgattagag
     6181 ataatatgaa taacctggaa caatggatgg cgcctaaaga agtcggttca tcgttaagcc
     6241 ctgacgcaaa cggaattctt atgtacgagc ctaaaggcgt cacactcatc ctcggcccgt
     6301 ggaactatcc gtttatgctg acgatggcgc cgcttgccgc ttctctcgca gccggaaaca
     6361 gcgcgattgt gaagctgtcc gatttcacga tgaacacgag caacattgct gctaaagtaa
     6421 taagagacgc ttttgatgaa aaagaagtcg cgatttttga aggagaggtt gaggtggcaa
     6481 ccgaactact tgatcagccg ttcgaccata ttttcttcac tggaagcaca aatgtcggga
     6541 aaattgtcat gacagcggct gccaaacact tggcatctgt cacacttgag cttggcggca
     6601 agagcccgac gatcattgac agtgaatacg atctgatgga cgcagcgaaa aagatcgccg
     6661 tcgggaaatt cgtaaacgcc ggccaaacct gcatcgcacc tgattacctg ttcattaaaa
     6721 aagacgttca ggacaggttc gcggggattt tacaaacagt cgtcaacgct ggatttatgg
     6781 aggatgatca taccccagac cgcagcaaat ttacgcagat cgtcaatgac cgcaacttca
     6841 accgcgtcaa agatctgttc gacgatgcca tcgaaagagg ggcggaagtg gtgttcggcg
     6901 gcgtattcga tgccagcgac cgcacgatct cgccaaccgt tttgaaaaac gtcacgcctg
     6961 acatgaaaat catgcaggag gaaatcttcg catcgatcct gccaatgatg aactatgaag
     7021 acatcgacga ggtcatcgat tacgtaaatg accgcgataa accgcttgca ctttatgtgt
     7081 tcagcaaaaa ccaagatctg attgacaacg tccttcagca cacgacatca ggaaatgccg
     7141 ccatcaatga tgtcgtcgtc catttcagtg acgtcaacct gccattcggc ggcgtcaaca
     7201 caagcggaat cggctcctat catggggtat acggattcaa agagttttct catgagaagg
     7261 gtgtatttat tcaggccgct gaataatcgc atgatcaaaa ggcgcttcct tagaggagcg
     7321 ccttttattg taactccttg accaaaagca attcatcacg gataggtatt ttattatctg
     7381 ccagtaaagg aatttcgggc ttcatctttc tggccgtctc gactgcattc acaaatagtc
     7441 gatccaaccg gtaccctctc ttctgataaa acgctaatgc atgaatatta tcattggttg
     7501 tgatcagttt tatttgtttg atatttctct ctctgcatgc ttcctcggct ttctctagca
     7561 gagctgttcc gatcccttta ttctcaatga cactatccag cgaaatgatt tcacaggcat
     7621 cttcttcaaa tatgtatgta ataaggccaa caatctggtt atcatcgttg agcattccat
     7681 aaccatctaa ttcatcgcag ttataaatac cgctagaaat aaccatttgc ggactgcccc
     7741 agtgtttttg aaaaaacgcg gaaacaagat ctttaggtat ctggcatgtc ggaataatat
     7801 tcatattttc ctccttttag ctgaacaaaa ataagagaat taacaaccta ttttatgtca
     7861 ttaatcccct tatctagtat ttactagaac ttataacttg tcaaaagctg tctgaatacc
     7921 aattgcgtgg attgataagg atcaaaatct gaatcctgag attggaagat ttgctctggg
     7981 gtcaatgtct ctgcgttctc tgataacgtt tgaatcagac tttccaaata tccatttaac
     8041 tctgatttgg acgattcatg tagggattga tgatttacag cgagttctct aaatctgtta
     8101 tcactgatta atttttttcg aagagctgct agcatcaagt caagccatgc aggctggcca
     8161 aatgtaatat ttaaagctaa cgttgcttga tcagatttgg tggagtgcca taaacctctt
     8221 ggcaaataca gcatggttcc cggtgttaaa ttaacgattt ctgcatctgg cagatcctct
     8281 tttggcggat ctcctttcca atatgactgt aaatcatcag gatagtaagg agcctctgat
     8341 aaatcatagt gctgcattgg attgctcaca ttttcattct tggcaagctt ccatgttttc
     8401 tcaccttgaa tttgaaaaat caagttggtg taggcgtcaa aatgggcttt gaatcccccg
     8461 ccatttttcg ccgcgtaaac aatggctttg gaagaagtac ccgcaggcag tcttaattcc
     8521 gctttgagtt tttctatcca ccttctgact tggggaataa ataggtcggt gaaatcaaac
     8581 tctaatgcag cccctttttc ataccactct aaagcctctg caggtgacac aagaaatctg
     8641 tctgtgatcc cttcagattc ttcaatcaca gcatcaccaa cgaccatgac tggattattg
     8701 tagatagcca atacgttttc tagcgttcta accttttcaa accccggtat gcttgtaaat
     8761 ctctccactt ctcctctggc taccaaaggt tttacaggcc aatattcttc taaaaactca
     8821 ctcatcgtta caggactgat gatagactcc aaaaccgatt cggttacagc actcatatta
     8881 tccctcccaa aaaaagtaac ttcaccacaa agatataaca tttttttcta aaagtaaata
     8941 ttgacagaat tatcagagga ttataatatt tagttgtgcg tgatagccta tttttttaca
     9001 aggaaggagg gaaaaggatg aaaaaggctt ataagaaacc tcgtcttttt gaactgcgcc
     9061 gtgctgtagc agctggcggc cattaatctc atatagcatt tgacatctag tactctattt
     9121 taggagggat gctcaatgaa aaaagcttat aagaaacctc gcctttttga attgcgccgc
     9181 gctgtagcag ctggcggtca ttaatcttat ccaaaacgat taacgtttga ggctatcacg
     9241 ccaacttgat aaggaggatg ctgaagatga ttacggctga agaatgcaga acgtacaaag
     9301 aatttgttga tctttaccaa tcctatcttt accccttgct tggcgccaga ctgtcccgga
     9361 tgtattcccc caaaaacaaa gtcattatcg atatgggcac aggtccaggt tatttaagca
     9421 ttcagttggc taaaagaaca aatgcgcacg tgcatgctgt cgatattaac ccggccatgc
     9481 atgaaatcgc tcaagaagaa gctaaaaaaa gcggagtaag cagcctgatt tcatttgatt
     9541 tggaagatgt ccaccattta tcttacgctg accaatatgc tgacttcatc gtctcctact
     9601 cttgcctgca tcattgggaa gacgttgtta aaggacttaa agagtgctat agagttctgg
     9661 ctccgggcgg aaaaattgtc attttggata catttaatcc ccaaggaagc catttagaga
     9721 ttatgcgaaa acaaatcaaa gaaccggaat acttcaggtt tgtaagagag gcatttgaag
     9781 aaagttattc ctttgaagac attcaccagt ttgttcagga tgccggcatt cccaattatt
     9841 cattagaaac ctttcacttt ttaccggagg attttataga aagcttagat gagctggagg
     9901 atgctcccct gtgggaacaa aatgatcaaa gtactgatca tgaaattgag tctgtcacat
     9961 ggatgttaac gatagaaaaa gaaaaggaag gtgcattgta atgatcaatg aatcaactgt
    10021 tttatccaaa aatccagaaa tgccatcaag aaaatatttg aaaagcatta ttatagagcc
    10081 gggcatcact ttaaatgaaa tggcatcaga tatttataac catatcgacg gcaaggtcag
    10141 catacatgat atttgctcaa aaatcgtcaa tgaatatgat gttgattatc aaacctgctt
    10201 agaagattgt atggagctgt ttgagttgct tattgatcat gaagcaatca aagttaagca
    10261 gggggcatga gaattggaaa aacaaaaagt gcttgcttta ccagacgatg tacatgagct
    10321 gagtacacac cgttctaaat caatcgtaaa ttacatcatc actctgcttg cctttgccaa
    10381 aaaacaagga ttgactcatc aagatattgt aagctggatt cacgagcaat atgaggaaag
    10441 aggatattat gatgagtgga gacacattaa cagccaacaa ccagttggat catttgtgga
    10501 actctttata aaaggaagac gtttacttta tgacaaaatt gaattgtttg aaacagaaga
    10561 taaatatgtc gtaaataccc acacttggta tgaaaaagaa cctagtgagg ccttttttta
    10621 ttttgaaatt gatcccgaag aattttctgc gtacgcttcc attctcgcaa tcgaaaacgc
    10681 aaaacgtctc ggaattaaaa tcgatattgt aaaagaaaca gatgtagaga cagcttatat
    10741 ctataaacat caataacgct attgggaggg agacatatgt gcgggctcgc gggtattata
    10801 aatctggctg ctccccgttc tcaggaatgt acctttcata tattgaaagg catggcagat
    10861 gccatcagct ataggggacc ggatgatgaa caatatcata ttgattccaa agtcggcttt
    10921 gcatttcggc gattgtccat tcttgacctt gtaaatggac agcagccctt tttaaatgag
    10981 gatggatcaa tcgtcgttat ggtaaatgga gaaatttata actataaaga actgaaggct
    11041 tctttacaca atcatatgtt taaaacgaca tctgattgtg aagtaattgt tcatttatat
    11101 gaagaaaaag ggattggatt tgtagacgac atcatcggaa tgttttcaat agccatttgg
    11161 gacaaaaata aaaacaaagt atttttagtt cgtgaccgct ttgggattaa accgcttttt
    11221 tacacagagc taaaacacga gcttatattt gcctctgaaa taaaatccct attttctcat
    11281 cctcactgtc cccgccaatt taattggaaa gaagcactct cagacatttg gctaagcggg
    11341 gaagcagcca gtaatcataa agaaaccact tccttttttg taaacatcca aaatctcgat
    11401 gctggccatt atctcgaaat taatttgaca acaaatgaac gaaaaacagc aagctattgg
    11461 tctttacagg atattttgct caggcaaggc tatcgtgaga atctccatcc cgatgacctg
    11521 attgaaggat atagagaact gctggcagat tcagtccata gatgtttaca aagcgacgtt
    11581 gaagtcgggt tgtttcttag cggtggcatt gattcagctg cagtcgcaca ttttgctgca
    11641 gaaaaacagg atctccatac gtttacagta ttaagccaaa gtacatttac aaatgaagat
    11701 gcaaaatatg cccattggct ggctaaagat ttacaccttc caaatcatca ggttctctat
    11761 caattaggga acgatgagtt attacaacca gagtcatata aacatttgtt atggatctgt
    11821 gaaacaccgt tttgcggacc ggaacaatta tataagtttc atttacataa gtatgccaaa
    11881 gcgataaggc caaacctgaa agtcatgctg accggccagg gcagcgacga atttaacggc
    11941 ggttacagca cgacactttc accagccgag aacccaagtt gggaaggatt tattgaatcg
    12001 gtcaatacga tggagatgaa ccggctgcat cggctgcagg gaaatatctt tagagtgtgg
    12061 gaggagcatt ttggactttc tcctataaac ctttcttatt taaagagcaa tgattccagc
    12121 caagcagatc cttggcaatc gtatgtcctg acaaaatacc gtgatctgca aatgtataat
    12181 tgctggcatg aagatcggat cgccgcggct aatcatatcg aaaaccgtgt accgttcttg
    12241 gaccatcggc ttgttgaatg ggtttgcgga atacctgatg gactccgtaa agacttgtta
    12301 tgggataagt cggtattgcg aaaatcatta acaaatgagc tgcatacaag ctatacccac
    12361 cggccaaagg ttcctttttt ctatggtaag gacgtgagat atacacataa aatgatgttt
    12421 catcttctga agaaaaacaa ttatcagctt atagaggagg ccttctctca cagcgatgcc
    12481 tccagcataa tacaggttga acacattcat gccatcatga catatttgga ggatgatcct
    12541 gagtttacaa attttgaatt tttattaaga ctggtgaaca tgggactttt atcaaaaatg
    12601 actaaagaaa ccccttctgt tcaattagac ataaccagcc atttagaatc gataacaata
    12661 aaagactggc actcacagga aggtgatatt gccagtcgtt taaatatctc agccaataag
    12721 tgtgaaggac aagatatttt ggcgctaaac cctggcgtca ctctgttaag gccggaaagc
    12781 gatagtgagc attgcatcta cattgcggaa gaaggattta ttcagtttat tgtttcggag
    12841 gaagacgtcg gagcttggct gcatattctc tgcgatatta atggaaaaga cacacttcat
    12901 acgattttag acagacatgg tgtcagcctt gaagaagtgg ccaaatatat tcaagaagcc
    12961 atcgaacaca atatcatttt gatcaaacaa aaaaatctgc cagaaggagc atatagatga
    13021 gcatctttta ttcgttttcc gcacttaggg gattagcaat ggggattttt tcgcctattt
    13081 ggattcttta tctgatatct aaagattatg atttccttca gattggatta atgggagcgg
    13141 tacttgaaat tgctaagctt atatttgaag ttccttccgg cgtttttgct gatcgttatg
    13201 gaattaaaat ttcaattgcc agttcattct ttttctccat ccttacatgg gccttcttcc
    13261 cttttatcga ttcagctgct atttgcatac tggctatgat catatgggct ttatcagatt
    13321 ccttaatttc cggttctttt gaaacttgga tgagccgtgt cgcaggggaa gatcgattcg
    13381 gcaaagaaat gatgaaaaac acacaattgc taatcacttt tttaattatt ggaagtattg
    13441 ccagcgggta tttgtattca ttaaatatct attttccttt cctgctcgtt atggtgatct
    13501 acttattact atttatttgg atgtctgtat ttattaaagt cccttctgtt tccgaaacaa
    13561 atcatgggga tcagaaccaa catgattcga taaagattat caaagaaagt ttaaaaatta
    13621 tctttaacaa aaaaagggtt cttttaatcg tcatagccgg tttctttaca gccacagcct
    13681 atgacacaat ttcccgttac tggcagcctt ttttgagtga tttaggcttt tcagaaaagt
    13741 cactgggata tatttttgcc ctaggagggt ttaccgctct cgttcttttg acattaacca
    13801 tcaggttcga aaagaagatc gaaaaaaatc catatctcgc tttaacctca ttggattcca
    13861 tgggcatggt catgactttt ctattgtcta gagcattcag gccgctgggc attccatgta
    13921 cagcgttttt gcttgcaatt gaagatattc atcatccgat cgtaacaagt tacttaaata
    13981 agtttttccc cgattcatac aagaacacac ttttctcgtt aaactcaggg gtaggagcaa
    14041 ttggagaaat tctttccggt gtcattttcg gcatcatttc cgcagccttt gggctctctg
    14101 ccatgtttgt tgttgtagct gtatttctat taatccctat tatcctttat acgatagtgc
    14161 ctaagattaa agacaatgat atgaaagttc agattgaaaa atcccagcaa gtgtaaatgt
    14221 tttgtatcac agtaagaaga ccttcttatt aaaagaaggt cttctgctat tctattcagt
    14281 tatttcccaa aagccatcag cttcgtataa cttccaatat aaagtgttcc gtcctcagcg
    14341 agctgaggag aagacacgac gttgctgtcg gtttgatagc tccataattc attgccgttt
    14401 gcgtctgccg cataaacctt catatcatct gacccgaaat aaaccgttcc cttcgcgtca
    14461 atcagcggcg ccgttctgac agggccgtct gtgtagaatg accagttcat atccccgttt
    14521 ttgctgatgg aaaacagctc gccgcttcct gagccgatgt agatattgcc attatgatca
    14581 atcgcaggag atgagctgga gaacccgttt agcgggaatg tccatttcaa actgcctgtt
    14641 gatgtataag catacagctg tccatcttgg ttgccggcat aaatgtttcc gtccttatca
    14701 atcaccggat atcctttaaa cgcatttgac gtcgttctgg accatttcac ctgtccggtt
    14761 ccggagttga tcgcataaaa cacgtaatta tatgtgccga catacacggt gccgtttttg
    14821 gcaagcaccg gcacagagct gacgacccca tttgttttca acttccagcg ctctgtccag
    14881 gttgattttg acgtcggttt gatcgcgtga acataattat caagtgttga gaaatacaac
    14941 gtcccgtctg aaccgatcac cgtttcagag cttggcccgc cgcttaacgg aaccgttgtt
    15001 aaaatttctc ccgtttcttt gtcaataaaa taaatctttt tgtcatagga tgccaaatag
    15061 ataacgccgt tggtcccaag tacaggagat tgcgtatatg tttttccaag attgcccgtc
    15121 acccatttga ctgagccgtc tggattaaag gctttcattt ccccgtctct ggaatgaaga
    15181 tatactgtgc cgtctccgtc aatcacagcc cccgctccat tttgcggagt cgttctgatg
    15241 tcgttttgcc atttcagcgt cccgtctgta tttccggcga accggctttc gcgtgaccag
    15301 ttaaacatgg caggcgccat cgcttgtaca tcatatcttc ctggcaaaaa gccagatgct
    15361 ccattatttt gagaaaacac cgtttccgcc gcataagcag ctgtcggctg aagcactttg
    15421 gcagcgggca catcagaaac agcgccggcc gaaacagccg ccgccaccgc agctcccgca
    15481 atcaaagctt tcatacgaaa tgacttgacc atcattgaga cccccattat atgtaacttc
    15541 taatttgtga ccatcataac atattcatcc attttataaa tctatttcac aaaaacatca
    15601 caaactagaa aactatgtaa gagtattcac ggacgttttt tcagcacccg atcgaaatgc
    15661 agccacaaac caaatgacgt tgacagcagc cgcagcgaga ctaactccca aaacaaagat
    15721 cacctcagaa agcagatggt cactaaagaa actaaacatc aagataaaac cggccgaaga
    15781 caaatgaatc aaaagcccga agccgcaaag caccgccatg acatacctca ttgcatcgac
    15841 tccgagcata taaacgagaa atggaatgaa atacaagaca aggatcatac cgacagctga
    15901 ccacatgcca gctgaattaa actgattggc cgccgctccc gttccggcca gcggcgaaag
    15961 tgaagccgcc acaatcacgg cgcaaaaaag aaacgcagaa atggttgtca tgatcgccac
    16021 gctatttttt tttgacatca aactcctcct ttaatagaaa tattaacctt ttttattata
    16081 agtaagttga atgttatatt cattatattt ttaaaaaatt ccagaataca tacacaaatg
    16141 ctatgcttct ttctagtata tttatatagt aaaaaacaaa ggataaaaga ctcatttttc
    16201 tgtaatatca ggattttatc accataccat attgcatgta catgtttttc aaagtatact
    16261 attccagatt aattcagagg agagagaaaa atacatggaa aaaccagcag gattttggat
    16321 tcgtttttta gcttatttta ttgacggcat tattgtatct gttcctagtt atattattct
    16381 atttattatc aattctgtgt ttgtagctgg ggctgtggca acaaaccctt acatgacgga
    16441 agaagagtat ttagtgaaat acatgacgct tgcatttttg cctactatgc tgatcatgat
    16501 cgtcatcagc gtgttatatt acgggctgct cacagcttct aaaatgcaag gcacacttgg
    16561 caaaaaaatt cttggcctga aagtggtcaa tgaacaaggt gaacgggttt ctgtcggaca
    16621 gggaattggc cgttactttg cctatatctt atctggaatc atcttttata tcgggtttat
    16681 catgatcgcc tttggagaga aaaaaggcct gcatgacatc atttgcaaaa cacgtgtcgt
    16741 gtataaataa tagaaaaaag tctagacgcc aataggcatc tagacttttg ttttctttgc
    16801 aataggctgc cacgacagat acgtagcgct tctccacaac cactcaaacg gccccatccg
    16861 aaagacacga agccaaaggt ggctgaagac catttgaacg gcacaaacag caattgtaat
    16921 gagcacaccg gcagcagggt acacttttcc atacaggccc aagccgtaat gataaaaaat
    16981 ccaagtacac acaatagact gcatcaaata attggtaaat gccatcctcc caacagcgga
    17041 gaatgattgc agcactgttc tcactcttgt tttatgataa agatagacaa ccgttgtaac
    17101 atagaaaaac atgaggaaag gcgcgccaat cagcaaacat atttctttat ccgttacact
    17161 gtacagcacc tgggcgccga tgccgatgac aagcccagcc atccataatc gttttaatcc
    17221 tttgcgatgc ttttccggtt catgcaaata ccgtgatttt gctgccgcag ctcccagcaa
    17281 aaacatgctg aaatatggaa tggatgcaaa gaagtagttg agcggattat acgtaagcat
    17341 gccattcgaa gacatgtaaa caagacggtc gtggatccgc tgttctgcaa tatccttcag
    17401 gctgccgctt ccataaacat gaatcgcttg ttttgcctgc tgtgttaccg cttgtaccca
    17461 ttcctgtccg tttgattgat caaaacttgt caacatgaac ggaatggaaa acagaagata
    17521 caaagagacc gcccatatca gcagtgtttt cggctttgct tttcgaaaca agagcaggac
    17581 aaatccgagc agggcatatt ctgttaaaat atccccgtcc catatcaaaa aggcatgaat
    17641 cgttccaaac aagagaagcg ccattaacct tctcacatat aacggaacaa accgtttccc
    17701 tttgttttct gctctctcca tcatgacaac catgccaaat ccaaataaaa aggaaaacaa
    17761 taaaatacat tttgtttgaa tgaagaattt cagtatgtct gcggcggcaa aatcagcttc
    17821 agaccactta tccatgaaaa aattctcttt tccaagcata gacaaataca tatccggata
    17881 actgaaatgt gccagattga caaataagat gccgaaaatc gccattcctc tcagcacatc
    17941 aagcacaccg atccgctcat ttgttaaagt cggctgtaat gaagacatag ccatcacgct
    18001 ccttttttct gtaccttaag ggtaggaaaa aatgaagcgc ggtaacatcg atttaggtgt
    18061 caggccggca tgaaaacctt acaatcttgt catctttatg gtttcatcac ctttaaatct
    18121 aatgcttcga tattctgcaa aatgcgatca aagcgcaaag cctgaggctc acatgggaag
    18181 atgtggcctt catacgggtc gcctaacgtc cggaaaaacg gttcaaataa accaggaacc
    18241 aatacgccca ccatctttgt atagtgagaa tcaaggcgat aggagtgaac ggtatttgca
    18301 gggacatgca ggaaatctcc cggattcagc tgaatttcct ggccatctgt ccacatcgtc
    18361 atctggcctt caaggcaata aaatgtttct gtatgatatt catggtagtg atcaacgatt
    18421 cggtcacctt tagggccttc agatgatacg acgataaact ggccatctgt atttttttgt
    18481 gcagccacaa tgcggtgaag ctgatctcca gtcaacagac gatctccttc tccagattca
    18541 agaacgtatg gaaccgctcc atctggcagc tctgtaagtt ccgctaattt ggccgaacat
    18601 gcaggctttg cttcatctag aaatacaatg tccgctacag cggctgcttc tgcaaatcgc
    18661 tcgtttgaga cttcttcgct tgcgtacggc ggatgttcag cgtgatcata cggattccca
    18721 ataacggaat acaagtgcgc tacgtttcct ttcatcgtgt aagacaccag tcttgttctg
    18781 tggctctgca tccggtagct gtgcggtgtt cccgccggaa tgttggcata atcacctgat
    18841 attaataaat agcgttcacc atcaagtgtc agttccagtt tcccgtccaa aacgagaatt
    18901 ccttcatgtg tgtccttgtg gacgtgaagc ggaaaggcat ctccttttcc cccggaaaga
    18961 agcacgatct caaacaaatc acctgtgctc ctcccattcg ccatcaccgt ggcaacctgt
    19021 ctgccgaaca gatagcgctc gccttctccg ctccggagca aataaggcat tttttcttta
    19081 ggcaatgaat gtgtacataa tgttttcata ttatcgcttc ctccaattta gaccagtcta
    19141 tatattatca ttcatttgtc tagaccgttc tatataattg taggagaaag gataacaaaa
    19201 tgctaccctt tttttctcac cagcactggt atttgttcgg caatgagaag aagaggcgtt
    19261 ttgtctttat tcgttaacga aagcatgatg ccgccctcaa tcatcgaatt aatcagcgtt
    19321 ccaagctgat ttgcttcttc ttctgcaaat ccgttttcca ttaattttct ggcaaaaacc
    19381 gcttcccagc ttttaaacac cttcatgcaa accgtccgca gcggttcact gattaacgct
    19441 gtctcactcg ccagcaaacc gactggaata cctttaatgc tttctgtgtt gtcaaattgg
    19501 ctggctgttt ttttgataaa aagctgaatc gcttcaacag gatcagagga ttcatccatg
    19561 ctttgctgta tcagatgttc aacgatctta cctgtatatg taaccgcttc aattgctagt
    19621 tcttctttgc cattcggaaa aaagtgataa agcgatcctt ttggagcacc gctttctttt
    19681 acaatctggt tcaaacctgt cgcgtgatat ccttgcagct ggaacagacg tgacgccgtg
    19741 tgaaggattt tttcacgtga atctcctctg ctagtcatta aaacattccc tcctaggtat
    19801 ggtagagcga cttatataat ataaaaaaga accctgtgat tgtcaaaagg ggtaagaccc
    19861 ttccggatgg ggtaatgtac aaaaacagcg tctaggaggg atctctcaat gacaatcgat
    19921 cattcagtca caaatacaga gcagcttgaa caacagaacc ccgccataaa aacaaagctc
    19981 aaactgaaaa agcttaagga tcaggtgatc gtcattaccg gcgcttcaag cggtatcgga
    20041 cttgtcacgg cgagaatggc agctgaaaaa ggcgcaaagg tcgtggcagc agcgcgaaat
    20101 gaagaggcgc tgaaggagct cactgatgaa cttaaggaaa aagggcacga cgccatatgg
    20161 gtaaaggcgg atgtcggaaa agaagaggac gtcaaccgca tcgcagaaac cgcgatcagc
    20221 acattcggcc gctttgatac atgggtcaac aatgcggccg tctcgacttt
//
