LOCUS       gnlProkkaHFNFGPLJ_87   15261 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFNFGPLJ_87.
ACCESSION   gnlProkkaHFNFGPLJ_87
VERSION     gnlProkkaHFNFGPLJ_87
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:56:39
            Original ID  :: gnl|Prokka|HFNFGPLJ_87
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15261
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15261
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1:11221]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..11221
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     protocluster    1..15261
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:2254]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2..2254
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     cand_cluster    1..15261
                     /SMILES="NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="betalactone"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15261
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="betalactone"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             2..2254
                     /NRPS_PKS="Domain: Condensation_DCL (2-222). E-value:
                     4.7e-86. Score: 280.4. Matches aSDomain:
                     nrpspksdomains_ctg59_1_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (387-742). E-value: 5.8e-96.
                     Score: 313.4. Matches aSDomain:
                     nrpspksdomains_ctg59_1_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     243.6; E-value: 5.5e-74)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_1"
                     /sec_met_domain="Condensation (E-value: 1.9e-66, bitscore:
                     213.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.1e-89, bitscore:
                     287.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLYSEDISHLPTNDQNEYIERFKEKDKQKGFDLQKDMLMRISLF
                     KTVKDEHVCIWSHHHILMDGWCLGIVMQEFMQIYQSIHAGKPLSLDPVRPYSTYISWLT
                     NRDKEKAAAYWDTYLKNYSTPSPLPRVSDKETKEGYHREDLIFSLNKPLTDKLKETAKQ
                     HGVTLAILIQAVWGVMLQQYNRTDDVVFGAVVSGRPSEIPGVEQMIGLFINTIPIRIKT
                     HQDETFQELLIRCQKKMLEAEPFTCQPLFDIQANTALKQELIDHIIVFENYPLQQKIAD
                     SADQTDSPLQIDQVQVSEQSGYNFNLVVAPGEELVVKFSYNAFVYDAAWISCIKRQFTQ
                     ALSTAAQHPHMPIADFSFLDATEKEQIVTQFNNTKTEYPKNHTIIDLFREQAEKTPDHT
                     ALVYGNMSISYKELDKRSNALARELIQKGFRKNETAGILAAHSPEFMISVLAVLKAGGA
                     YLPLDEELPPERVSFMLEETQAKMLIVQKGLEQNAAFSGTCMIADAQALMGENHFPINT
                     ISSPDDLAYIMYTSGSTGRPKGVMITNRNVVSLVRNSNYTSASGDDRFILTGSISFDAV
                     TFEMFGSLLHGASLHIIDKSTMLTPDRFGAYLLENDITVLFLTTALFNQLAQVRSDMFR
                     GLHTLYVGGEALSPALMNAVRHACPDLALHNIYGPTENTTFSTFFEIKRDYAGPIPIGK
                     PISNSTAYILDTKGRLLPIGVPGELCVGGDGVAKGYLNRDDLTNTVFSPHIAKKLG"
     aSDomain        8..667
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg59_1_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="4.70E-86"
                     /label="ctg59_1_Condensation_DCL.1"
                     /locus_tag="ctg59_1"
                     /protein_end="222"
                     /protein_start="2"
                     /score="280.4"
                     /tool="antismash"
                     /translation="LYSEDISHLPTNDQNEYIERFKEKDKQKGFDLQKDMLMRISLFKT
                     VKDEHVCIWSHHHILMDGWCLGIVMQEFMQIYQSIHAGKPLSLDPVRPYSTYISWLTNR
                     DKEKAAAYWDTYLKNYSTPSPLPRVSDKETKEGYHREDLIFSLNKPLTDKLKETAKQHG
                     VTLAILIQAVWGVMLQQYNRTDDVVFGAVVSGRPSEIPGVEQMIGLFINTIPIRIKT"
     aSModule        8..3122
                     /complete
                     /domains="nrpspksdomains_ctg59_1_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg59_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg59_2_PCP.1"
                     /domains="nrpspksdomains_ctg59_2_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg59_1"
                     /locus_tags="ctg59_2"
                     /monomer_pairings="Ile -> Ile"
                     /monomer_pairings="Ile -> Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       173..238
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_1_0001"
                     /evalue="5.60E-13"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg59_1"
                     /protein_end="79"
                     /protein_start="57"
                     /score="41.2"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVMQEFMQIY"
     CDS_motif       563..658
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_1_0002"
                     /evalue="6.90E-22"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg59_1"
                     /protein_end="219"
                     /protein_start="187"
                     /score="69.9"
                     /tool="antismash"
                     /translation="DVVFGAVVSGRPSEIPGVEQMIGLFINTIPIR"
     CDS_motif       707..823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_1_0003"
                     /evalue="2.80E-16"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg59_1"
                     /protein_end="274"
                     /protein_start="235"
                     /score="51.9"
                     /tool="antismash"
                     /translation="QKKMLEAEPFTCQPLFDIQANTALKQELIDHIIVFENYP"
     aSDomain        1163..2227
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg59_1_AMP-binding.1"
                     /evalue="5.80E-96"
                     /label="ctg59_1_AMP-binding.1"
                     /locus_tag="ctg59_1"
                     /protein_end="742"
                     /protein_start="387"
                     /score="313.4"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FREQAEKTPDHTALVYGNMSISYKELDKRSNALARELIQKGFRKN
                     ETAGILAAHSPEFMISVLAVLKAGGAYLPLDEELPPERVSFMLEETQAKMLIVQKGLEQ
                     NAAFSGTCMIADAQALMGENHFPINTISSPDDLAYIMYTSGSTGRPKGVMITNRNVVSL
                     VRNSNYTSASGDDRFILTGSISFDAVTFEMFGSLLHGASLHIIDKSTMLTPDRFGAYLL
                     ENDITVLFLTTALFNQLAQVRSDMFRGLHTLYVGGEALSPALMNAVRHACPDLALHNIY
                     GPTENTTFSTFFEIKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGELCVGGDGVA
                     KGYLNRDDLTNTVFS"
     CDS_motif       1349..1390
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_1_0004"
                     /evalue="4.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg59_1"
                     /protein_end="463"
                     /protein_start="449"
                     /score="19.7"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       1574..1630
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_1_0005"
                     /evalue="2.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg59_1"
                     /protein_end="543"
                     /protein_start="524"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGRPKGVMIT"
     CDS_motif       2135..2224
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_1_0006"
                     /evalue="7.60E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg59_1"
                     /protein_end="741"
                     /protein_start="711"
                     /score="50.2"
                     /tool="antismash"
                     /translation="PIGVPGELCVGGDGVAKGYLNRDDLTNTVF"
     CDS             2247..3152
                     /NRPS_PKS="Domain: PCP (2-69). E-value: 4.3e-24. Score:
                     76.4. Matches aSDomain: nrpspksdomains_ctg59_2_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (89-292). E-value: 6e-42.
                     Score: 136.5. Matches aSDomain:
                     nrpspksdomains_ctg59_2_Thioesterase.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_2"
                     /sec_met_domain="PP-binding (E-value: 1.4e-18, bitscore:
                     57.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEEELANIWKQVLGVNTISIDDDFFAIGGHSLKALQVIHTLKHQ
                     QNIDIPIDFLFEHPTIAQLAEKLYSKQLTAADEQHVIKLNQHGAQNLFCFPPISGFGIY
                     FKDLALLLNEKAAVYGFHFIEQDTRIEQYVNCMTDIQPEGPYVLLGYSAGGNLAFEVAQ
                     AMERKGLEVSDFIIVDAYLKEQPLPIDTGNDESAAYLPEAVREKVMKKKRNYQEYWAQL
                     LNEGHIKASIHFIEAGIQIETSENTGLTKWEGACGNYSEYTGFGAHKDMLEGTYAEKNA
                     DIILDILEKITSNKAIPHKQ"
     aSDomain        2253..2453
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg59_2_PCP.1"
                     /evalue="4.30E-24"
                     /label="ctg59_2_PCP.1"
                     /locus_tag="ctg59_2"
                     /protein_end="69"
                     /protein_start="2"
                     /score="76.4"
                     /tool="antismash"
                     /translation="EEELANIWKQVLGVNTISIDDDFFAIGGHSLKALQVIHTLKHQQN
                     IDIPIDFLFEHPTIAQLAEKLY"
     aSDomain        2514..3122
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg59_2_Thioesterase.1"
                     /evalue="6.00E-42"
                     /label="ctg59_2_Thioesterase.1"
                     /locus_tag="ctg59_2"
                     /protein_end="292"
                     /protein_start="89"
                     /score="136.5"
                     /tool="antismash"
                     /translation="QNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTRIEQYV
                     NCMTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGN
                     DESAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIQIETSENTGLTKW
                     EGACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKIT"
     CDS_motif       2517..2546
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_2_0001"
                     /evalue="2.40E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="ctg59_2"
                     /protein_end="100"
                     /protein_start="90"
                     /score="10.9"
                     /tool="antismash"
                     /translation="NLFCFPPISG"
     CDS_motif       2667..2738
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_2_0002"
                     /evalue="5.60E-14"
                     /label="NRPS-te1"
                     /locus_tag="ctg59_2"
                     /protein_end="164"
                     /protein_start="140"
                     /score="44.3"
                     /tool="antismash"
                     /translation="QPEGPYVLLGYSAGGNLAFEVAQA"
     CDS             3261..3653
                     /locus_tag="ctg59_3"
                     /transl_table=11
                     /translation="MDHLSFLTFIMLILASYRLTHLIVFDKITEFIRKPFMKKKRIVDQ
                     NGHVDEKSVPASNFGYMLNCYWCAGVWCAILIGLGYLFLPRIAIPLIFILAIAGAQAIL
                     ETAVGVGVKLIDVLKSLQTMINDKKS"
     CDS             3789..5321
                     /locus_tag="ctg59_4"
                     /transl_table=11
                     /translation="MKVCQKSIVRFLVSLIIGTFVISVPFMANAQSDRELRAVWIASVL
                     NIDWPSKKGLSVKEQKQEYIKLLDDVQKMGMNAVIVQIKPTADAFYPSAYGPWSEYLTG
                     VQGKDPGYDPLAFMIEETHKRNLEFHAWFNPYRITMNHTDLNKLSESHPARKHPDWVAA
                     YGNQLYYHPGIPETRDFIVKGIEEVVKHYDIDAVHMDDYFYPYKIAGQEFPDQAQYEQY
                     GKGAFSNIDDWRRDNVNQLVKQINQTIKAEKPYVKFGISPFGVWRNAADDPTGSNTKAG
                     VRNYDDLYADTRHWIQEGDIDYIAPQIYWSIGFNAAAYDVLADWWSNEVKNRPVHLYIG
                     QAAYKINNNFDPPWSDPEEYVRQITLNRQLELVKGSMHFSLKDLNKNPLGIKDRLIADL
                     YSKPALVPQMPWLDNTAPKKPKLTKVTEDKNGNLLQIKDHPSNQKTKETAYYAIYRAEG
                     KKQNTLLATQRKTHEQQTFLDNTADPNKKYTYYVTSADRLHNESKASKRTTK"
     CDS             5892..7034
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 457.5; E-value:
                     6e-139)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_5"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9.8e-41, bitscore:
                     128.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.3e-29, bitscore:
                     91.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.5e-57, bitscore:
                     182.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQQMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFEKM
                     GELGLMGIPFPEEYGGSGGDTISYALAVEEVGKACGSTGLSYAAAVSLGASPLYYFGTE
                     EQKQTHLTPLASGTALGSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNASYA
                     RTVIVTAVTGKNKDGKNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDVRVPA
                     ANLLGDPTKGFKQFLYTLDGGRISIAALAVGIAQAALDASLAYAKERKQFGQPISSFQA
                     IQFKLADMAMEIDLARQMVLKAAWLKDHNHPFTKEAAYAKLFASEMATRACNQAIQIHG
                     GSGYMKEYGVERMLRDAKLMEIGEGTSEIQRLVIARQLLK"
     CDS             7078..8727
                     /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 9.8e-106.
                     Score: 345.6. Matches aSDomain:
                     nrpspksdomains_ctg59_6_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     459.7; E-value: 1.6e-139)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_6"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-116, bitscore:
                     379.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELIHSTIGRLLEQTADAYPDRDAVVYPDRNIRYTYAQFDSLCR
                     QTAKGLMRMGIGKGDHVAIWASNIPEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQ
                     SDAAALIIMDSYRGTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLAGMY
                     HWDETEILAKTVTDAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANI
                     AECMALTSQDRMCIPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCT
                     ALHGVPTMFIAELHHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQ
                     TEASPVITQTRANDSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVM
                     KGYYKDKEATRKAINHDGWLFTGDLAVMDEDGYCRITGRLKDMLIRGGENIYPREIEEF
                     LYRHPAVLDVQVVGVPDAKFGEEAAAWIKLKDGKSVSPDELKAYCKGKIARHKIPRYVI
                     FTDDYPMTASGKIQKYKLREKTIEMFNLSSSQ"
     aSDomain        7117..8412
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg59_6_AMP-binding.1"
                     /evalue="9.80E-106"
                     /label="ctg59_6_AMP-binding.1"
                     /locus_tag="ctg59_6"
                     /protein_end="445"
                     /protein_start="13"
                     /score="345.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EQTADAYPDRDAVVYPDRNIRYTYAQFDSLCRQTAKGLMRMGIGK
                     GDHVAIWASNIPEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQSDAAALIIMDSYR
                     GTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLAGMYHWDETEILAKTVT
                     DAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANIAECMALTSQDRMC
                     IPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCTALHGVPTMFIAEL
                     HHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQTEASPVITQTRAN
                     DSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVMKGYYKDKEATRKA
                     INHDGWLFTGDLAVMDEDGYCRITGRLKDMLIR"
     CDS_motif       7663..7713
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_6_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg59_6"
                     /protein_end="212"
                     /protein_start="195"
                     /score="23.3"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     CDS_motif       8233..8310
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_6_0002"
                     /evalue="2.50E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg59_6"
                     /protein_end="411"
                     /protein_start="385"
                     /score="13.5"
                     /tool="antismash"
                     /translation="GMQGELCTRGYHVMKGYYKDKEATRK"
     CDS             8737..10071
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     651.2; E-value: 3.5e-197)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_7"
                     /sec_met_domain="ATP-grasp (E-value: 1e-10, bitscore: 31.3,
                     seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.1e-17,
                     bitscore: 54.0, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTKVLIANRGEIAMRIIRTCSRLGIKTVAVYSEADKDALHTKAA
                     TEAYLIGESRVSESYLNIERIIKTAKKANADAIHPGYGLLSENSRFAERCKQENIVFIG
                     PSPDIIAKMGSKIEARKAMEAAGVPVVPGVSESLGDIEAACRTACQIGYPVMLKASAGG
                     GGIGMQRVENEEALKKAYEGNKKRAADFFGDGSMYIEKVIEHARHIEVQLLADQHGHTV
                     HLFERDCSVQRRHQKVIEEAPSPFVDDELRMKIGQTAVKAAKAIGYTNAGTIEFIVDQK
                     QNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLRIAAGHTLTFSQKDIQRNGHAIEVRIY
                     AEDPKTFFPSPGTITAFSLPDQKGVRHECAVAKDSTVTPFYDPMIAKMIVKGQTRTEAI
                     EKLETSLRDYRVEGIKTNLPLLIQAAATKAFKEGDVTTDFLKQHL"
     CDS             10086..10307
                     /locus_tag="ctg59_8"
                     /transl_table=11
                     /translation="MTVSIQMAGNLWKVHVKAGDQIEKGQEVAILESMKMEIPIVADRS
                     GIVKEVKKNEGDFVNEGDVLLELSNSTQ"
     CDS             10322..11221
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 265.7;
                     E-value: 1.4e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_9"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-51, bitscore:
                     165.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPKKVKIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSYI
                     EITSFVHPKWIPALRDAIDVAKGIDRLKGVTYAALVPNQRGLENALEGGINEACVFMSA
                     SETHNRKNINKSTSESLHILKQVNNDAQKANLTTRAYLSTVFGCPYEKDVPIEQVIRLS
                     EALFEFGISELSLGDTIGAANPAQVETVLEALLARFPANQIALHFHDTRGTALANMVTA
                     LQMGITVFDGSAGGLGGCPYAPGSSGNAATEDIVYMLEQMDIKTNVKLEKLLSAAKWIE
                     EKMGKPLPSRNLQVFKSS"
     CDS             11242..12024
                     /NRPS_PKS="Domain: ECH (10-252). E-value: 2.2e-70. Score:
                     228.6. Matches aSDomain: nrpspksdomains_ctg59_10_ECH.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 262.7; E-value:
                     4.2e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_10"
                     /transl_table=11
                     /translation="MGDSILFTVKNEHMALITFNRPQAANALSAEMLRNLQMILQEIEF
                     NSNIRCVILTGTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAI
                     NGSALGGGLELALACDLRIAAESAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIY
                     TGRRVTAHEAKEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDL
                     ATGLAIEQKAYEQTIPTKDRREGLQAFQEKRRAVYKGI"
     aSDomain        11272..11997
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg59_10_ECH.1"
                     /evalue="2.20E-70"
                     /label="ctg59_10_ECH.1"
                     /locus_tag="ctg59_10"
                     /protein_end="252"
                     /protein_start="10"
                     /score="228.6"
                     /tool="antismash"
                     /translation="NEHMALITFNRPQAANALSAEMLRNLQMILQEIEFNSNIRCVILT
                     GTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAINGSALGGGLE
                     LALACDLRIAAESAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEA
                     KEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDLATGLAIEQKA
                     YEQTIPTKDRREGLQAFQEK"
     CDS             12041..13570
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 545; E-value: 3.3e-165)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_11"
                     /transl_table=11
                     /translation="MDYEKERTERAERIRKGGAEKYHQGNREKGKLFVRERLSLLFDDD
                     IELEDAFFAECMSDGLPADGVVTGIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQ
                     ETAEKLNCPLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSA
                     AGGAYIPAFCDIVVMVDGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDIL
                     AETEEEAIQLARAYLSYFPANFQEKAPIHEKRPPKHFKTPLADVIPQNQNAPFDMHELI
                     ERVIDEDSFFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSADKAAKFIT
                     LCDAFHIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAG
                     LYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERAAFISSKREEYK
                     EDINIYRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV"
     CDS             13740..14939
                     /locus_tag="ctg59_12"
                     /transl_table=11
                     /translation="MYHLYSHNDLDGVGCGIVAKLAFGKDVEIRYNSVNGLNAQVQYFL
                     EKAKESNRQDALFITDLAVNEENEERLNEYVHAGGKVKLIDHHKTALHLNEHEWGFVQV
                     EYDDGRLTSATSLLYGYLVENGFMKPTNALDQFTELVRQYDTWEWERYDQKQAKRLNDL
                     FFLLSIDEFEAKMIQRLSAHDEFFFDDFEEKLLDLEDEKIERYLRRKKREMVQTFVHEH
                     CVGIVHAESYHSELGNRLGKDNPHLDYIAILSMGSKRVSLRTIHDHIDVSEIAGRYGGG
                     GHAKASGCSITDEVFELFVAEAFRIDPVRPDAFRNIYNLKGSANGSLYENRAQMRFFLF
                     PLDNEWNIQINGETQDETFAAFEEAEWFIKRNYAASLVRDEVFVAFLAENLKLANQHRK
                     "
     CDS             complement(14988..15260)
                     /gene_functions="other (smcogs) SMCOG1188:hypothetical
                     protein (Score: 75.5; E-value: 5.1e-23)"
                     /gene_kind="other"
                     /locus_tag="ctg59_13"
                     /transl_table=11
                     /translation="MSARFIPVVRHAISIPAGIARMPFLKFVVLTVLAIIPWSILFVYL
                     GIQLGSQWDDVENIAGTYTTPIMILAVVVIALYFVIKKRTAIFKR"
ORIGIN
        1 attccatttg tacagcgaag acatttctca tctgccaaca aacgaccaga atgagtatat
       61 tgaacgcttt aaagagaagg acaagcaaaa aggctttgat ctgcaaaaag acatgctgat
      121 gcggatttct ctattcaaaa cagttaaaga tgaacatgtc tgtatctgga gtcaccatca
      181 tattttaatg gacggatggt gcctaggtat tgttatgcag gaatttatgc aaatttatca
      241 atcgattcat gcaggaaaac cgctttcatt agaccctgtc cgtccgtaca gcacctatat
      301 ttcctggctg acaaaccgag acaaagaaaa agcagcagcc tactgggata cctatttaaa
      361 aaactacagc actccatcac ctctgcctcg tgtgtctgat aaagaaacaa aagaaggtta
      421 tcaccgtgaa gatttgatat tttcattaaa taaaccactg acagacaagc tgaaagagac
      481 tgccaaacaa cacggcgtca cgctcgctat cctaattcag gcggtctggg gtgtgatgct
      541 gcagcaatat aatcgcacag acgacgttgt gtttggcgca gttgtatcag gaagaccgtc
      601 agaaatcccg ggcgtggagc aaatgatagg gttgtttatc aataccatac cgattcgaat
      661 taaaacacat caagacgaaa cgtttcaaga actgctcata cgatgccaga aaaaaatgct
      721 ggaagctgag ccgtttacct gccagccttt atttgatatt caggcaaaca ccgcattaaa
      781 acaggaactg attgatcaca ttatcgtctt tgaaaactat ccgttacagc agaaaatcgc
      841 cgattccgct gatcaaaccg attcaccgct gcaaatcgat caagttcaag tatccgagca
      901 atcaggatat aactttaatc ttgtcgttgc tcccggcgaa gagcttgtcg tcaagttcag
      961 ctataatgca ttcgtttacg atgctgcctg gatcagctgt atcaagaggc aatttacgca
     1021 agcgcttagc acagctgcac agcaccctca tatgccaatt gctgattttt cttttcttga
     1081 tgcaacagaa aaagagcaga ttgtcacaca gttcaacaat acaaaaacgg agtatccaaa
     1141 gaatcataca attatcgatt tatttcgcga acaagcagaa aagacgccag accataccgc
     1201 acttgtgtat ggcaatatgt ctatttcgta taaagagctt gataaacgct ctaatgcgct
     1261 cgccagagag ttaattcaaa agggatttcg gaaaaacgag acagccggaa tattggctgc
     1321 acattctccc gaattcatga tcagtgtgct tgccgtatta aaagcagggg gagcatacct
     1381 cccgcttgat gaggagcttc cgcctgaacg agtcagcttt atgcttgagg aaacgcaggc
     1441 aaaaatgctg attgttcaaa aggggctgga gcaaaatgct gcgttctcag gaacatgtat
     1501 gattgcagat gcgcaggcat tgatgggaga gaaccatttt cctatcaaca ccatctccag
     1561 tccagacgat cttgcatata tcatgtatac ctcaggatca acaggccggc cgaaaggggt
     1621 catgatcacg aatcgcaatg tcgtgtccct tgtcagaaac agcaattaca cgtctgcgtc
     1681 cggtgatgac cggtttattc tgactggatc tatcagcttt gacgccgtca cctttgaaat
     1741 gttcgggtca cttttacatg gcgcaagcct tcatatcatt gataaatcga caatgctgac
     1801 acctgatcgg tttggagcgt atttgcttga aaatgacatc acagtgctat ttttaacgac
     1861 agctcttttt aatcagctgg cacaggtacg atctgatatg tttcgcggac tccatacgtt
     1921 atatgtcgga ggagaagcac tttcgcctgc tctgatgaat gctgtcaggc acgcctgccc
     1981 agatctcgcg cttcataata tttacgggcc tacggaaaac acgacttttt caaccttttt
     2041 tgaaataaag agagactatg cggggccgat tccgattgga aaaccaatca gcaatagcac
     2101 cgcttacatc ttagatacaa aaggacgtct tttgccaata ggcgttcccg gcgagctttg
     2161 tgttggcggt gatggggtcg ctaaaggcta tttgaacaga gatgacctga caaatactgt
     2221 tttttctcct catattgcca agaaacttgg ttgaagaaga attggcgaac atttggaagc
     2281 aagtcctcgg tgttaacaca atcagtattg atgatgactt ctttgctatt ggcggacatt
     2341 cactaaaagc actgcaagtc atacatacac tcaaacatca gcagaacatt gacataccga
     2401 ttgatttctt gttcgaacat ccgacaatcg ctcagcttgc cgaaaaactt tattctaaac
     2461 agctgacagc ggcagatgaa cagcatgtga tcaaactgaa ccagcacggc gcgcaaaatc
     2521 ttttctgctt cccgccgata tcgggatttg gcatttattt caaagacctt gctttattac
     2581 tgaatgagaa ggcagccgta tacgggtttc actttattga acaagacacc cgcattgaac
     2641 aatatgttaa ttgcatgacg gacatacagc ctgagggccc atacgtttta ttaggctact
     2701 ctgcaggcgg aaacctggct tttgaagtgg cacaggctat ggagcgcaaa ggattagaag
     2761 tcagcgactt cattatcgtg gacgcttatc taaaagaaca gcctttgcct attgataccg
     2821 ggaatgacga atctgcagca tatctgcctg aagcagtcag agaaaaagtg atgaagaaaa
     2881 aaagaaacta tcaagaatat tgggcacaat tgctgaatga agggcacatc aaagcaagca
     2941 ttcatttcat cgaagctgga attcaaatcg aaaccagcga gaatacaggc ttaacgaaat
     3001 gggaaggcgc ctgcggaaac tacagcgagt acacgggttt tggcgctcat aaagacatgc
     3061 tggaaggaac atatgctgaa aagaatgctg acatcatcct cgacatttta gaaaagatca
     3121 cttcaaataa agcaatcccg cacaaacaat agagcggatt cgcggacaga ggcattctct
     3181 gtccgcttct tttttgtatc aaagaatgga tcgatgacac tagggaatga taacatcatc
     3241 ctttttcttg gaggcttgtc atggatcatt tatcttttct tacgtttatc atgctgattc
     3301 tagccagtta caggctgaca catttgattg tattcgacaa aatcacagaa tttatccgaa
     3361 aaccttttat gaaaaagaaa aggattgttg atcaaaacgg gcatgtagat gaaaaaagcg
     3421 tgccggcttc taactttgga tacatgctca attgctactg gtgtgccggt gtttggtgtg
     3481 ccattttgat cggacttggc tatctttttt tgcctcgtat tgcaataccg ctgatcttta
     3541 ttttagctat tgccggagca caagcgatcc ttgaaacggc tgtcggtgtc ggcgtaaaac
     3601 ttattgacgt gttaaaaagt ctgcaaacca tgattaatga taaaaagtcc taaaagcggt
     3661 tcacaacatg ctttaggact tttttcgttt atttagtgag atagacattc tgttaatcac
     3721 ccttttatag cccgggaata ccgtaatagc gaatagtgaa agtgatgtaa tgggggagaa
     3781 gaaacagaat gaaggtttgc caaaagtcga ttgtccgttt ccttgtcagc ttgatcatcg
     3841 gaacgtttgt catttccgtt ccgtttatgg ccaatgcgca gtctgacagg gagctgagag
     3901 ccgtatggat tgcttccgta ttaaatattg attggccgtc gaaaaaaggg ttatctgtga
     3961 aagagcaaaa acaggagtat atcaaactgc tggacgatgt gcaaaaaatg ggaatgaatg
     4021 ccgttatcgt tcagattaaa ccgacggctg atgcctttta tccgtcagct tacgggcctt
     4081 ggtcggaata cttaaccggt gtccaaggga aggacccggg ctatgatcct cttgcattta
     4141 tgattgaaga aacccataaa cgaaatttgg aatttcatgc gtggtttaac ccttaccgta
     4201 ttacaatgaa tcatacagat cttaataaat tgtctgagag tcacccggca agaaaacatc
     4261 cagattgggt tgccgcctat ggaaaccagc tgtattatca tccaggcatt ccagaaacga
     4321 gagattttat cgtcaaaggc attgaagaag tcgtaaaaca ttatgatatc gatgctgttc
     4381 atatggatga ttatttttac ccttataaaa tagcaggaca ggaatttcct gatcaagcac
     4441 agtatgaaca atacggaaaa ggcgcttttt ctaatatcga tgactggcgg cgggacaatg
     4501 tgaaccagct tgtcaaacaa atcaaccaaa caattaaagc tgaaaaaccg tatgtcaaat
     4561 tcggcatcag tccctttgga gtatggagaa acgccgcaga tgacccgacc ggatcgaata
     4621 caaaagcagg cgtcagaaat tatgatgatc tatatgcaga cacaagacat tggatccaag
     4681 aaggcgacat cgattatatt gctccgcaaa tttattggag tatcggcttt aacgcagcgg
     4741 cttacgacgt gctggctgat tggtggagca atgaagtcaa aaataggcct gttcacttat
     4801 atattggcca ggcagcatat aaaatcaata acaattttga tccgccttgg tccgaccctg
     4861 aggaatatgt gcggcaaatc actttgaacc gccagcttga actggtgaaa ggaagcatgc
     4921 atttcagcct caaggacctc aacaaaaatc cgcttggcat caaagacagg cttatcgccg
     4981 atctttacag caagccggca ctggttccgc aaatgccttg gcttgacaat accgccccaa
     5041 aaaaaccgaa gcttacgaaa gtcaccgaag acaaaaacgg caatcttctg cagattaaag
     5101 atcacccatc aaatcaaaaa acgaaagaaa cagcctatta tgcgatatac agagccgaag
     5161 ggaaaaagca gaacacattg ctggcaacgc aaagaaaaac acatgagcag caaaccttct
     5221 tagataacac ggcagatcct aacaagaaat atacgtatta tgtcacttca gcagaccggc
     5281 ttcataacga aagcaaggct tccaaacgaa caacaaaata agaaatgaga aggacgactt
     5341 tctaagtcgt ctttttttaa aagtgatttt ggagacagga aacgatggtg aaccgctgta
     5401 ggcggtgttt ggacattttc cattattgga atctgagaag ctagtactaa gtaaattcga
     5461 agagaaacac gtacaggacg tgttttacgt tttcattgtt gactgatccg gctgaagaag
     5521 cctttttgcc gaactttctt ctcttgggag cggacaccgc tcttgtttta tgccttgtgt
     5581 tctttctcta tcaaaaactc gatcaatcac agttcgcggt gataaagcta ggtatatggg
     5641 gatcagcggt cggtttattg attgatacga tttccctttg gaatcatccc ctcatcctcc
     5701 cggctttatc aaagggccaa gttattgcgt ttgcgatatg gatggtatgc gcctactgca
     5761 tgtatttgct cattccgctg aaattatcac ataaaaaatg attcagtttt aattttcaga
     5821 cttttcttgt cagggaatga ttatagaact cgcctaatag gatgttacaa agatgtgaag
     5881 gaggaaacga tgtgaatttt gagctgacaa aagaacaaca aatggtgcgt gaaatggtaa
     5941 aagattttgc gaaaaaagaa attgctcctc acgctgaaca tgtagatcaa acaggcgagt
     6001 tcccgatgca aacatttgaa aaaatgggtg aactcggtct gatgggtatt ccatttccag
     6061 aagaatatgg cggatctggc ggtgatacga tttcatatgc cttagcggtt gaagaagtcg
     6121 gcaaagcctg cggcagtact ggattaagct atgctgcagc ggtctcgcta ggcgcaagcc
     6181 ctctttacta cttcggaaca gaagagcaaa aacagacgca tttgacgccg ctggcttcag
     6241 gcacagcact cggatcattc ggcctgacgg agccaaatgc cggctcagat gcaggaggca
     6301 ctcaaacaaa agcgatttca aatggtgacg agtatgtaat caacggcgaa aagtgctgga
     6361 tcactaatgc aagctacgca cgcacagtta ttgtaaccgc cgtaacaggc aaaaacaaag
     6421 acggaaaaaa catcatctcc gcattaatcg tgccaactga cacaccagga cttacgatta
     6481 cgagcccgta cgataaaatg ggcgtccgcg gttcgaatac agcggaaatt ttgcttgagg
     6541 atgtaagagt gcctgcggcc aacttacttg gcgatccaac aaaagggttt aaacagtttc
     6601 tatatacgct ggacggaggg cgaatctcca tcgctgctct tgcagtcggc attgcccaag
     6661 cggcccttga cgcatcattg gcatatgcga aagaacgaaa gcagtttgga cagccgattt
     6721 cttcctttca agcgattcaa tttaagcttg ctgacatggc gatggaaatt gatctggcac
     6781 ggcaaatggt gttaaaagcc gcctggctga aagaccataa ccacccgttc accaaagaag
     6841 cggcgtacgc caagctattc gcatctgaaa tggcgacaag agcttgcaat caagccattc
     6901 aaatccatgg aggttcaggc tatatgaaag agtatggggt ggaacggatg ctgcgggatg
     6961 caaaattaat ggaaatcggt gaaggcacat ctgaaattca gcgtctcgtg atcgccagac
     7021 agcttttaaa ataaaaatgt aaacgctttc ctatcattaa gaaaggagga acaatgaatg
     7081 gctgaactca tccattccac aatcggcagg ctgctggaac aaacagctga tgcgtatccc
     7141 gatcgagatg ctgttgtgta tccagaccga aatatccgct atacgtacgc tcaatttgac
     7201 agcctgtgcc gtcaaaccgc taaaggtctt atgcggatgg ggattggaaa aggagaccac
     7261 gtcgccatat gggcttctaa tatccctgaa tggcttgccg tccagttcgc aactgcgaag
     7321 atcggagccg tgctcgtaac cgtcaatacc aattatcaag cacacgagct ggactacttg
     7381 ttaaagcaat cggatgccgc cgcgcttatt atcatggatt catacagggg cacttcttat
     7441 ccagacatcg taaacagttt aattccagaa ctgcaagaag caaagcccgg ccaactgaaa
     7501 tctgaacgct atcccttttt aaaaacgctg atctatattg gcaataaacg gttggctggc
     7561 atgtatcatt gggacgagac agagatattg gcgaaaacag tgacagatgc tgagcttgaa
     7621 gagagaatga acagcctgga taaagacaat gtgattaata tgcaatacac atcaggaacg
     7681 acagggtttc caaaaggcgt gatgctgacc catttcaatg tcatcaataa cgctgctaat
     7741 atcgctgaat gtatggcttt aacctctcaa gaccgcatgt gcatcccggt tccgtttttt
     7801 cactgctttg gatgcgtcct tggggttttg gcatgtgtat ccgtcggggc agccatgata
     7861 cccgtgcaag aatttgatcc cgttaccgtc cttaaaacgg tagaaaaaga gaaatgcaca
     7921 gcgctccatg gtgtgcctac catgtttatc gctgagctgc atcatccgga ttttgatgca
     7981 tatgatctat cgacgctccg aacaggaatc atggccggct ctccctgtcc aagtgaagtg
     8041 atgaaagctg tgattgaaag gatgggcatg aaagacatta cgatcgccta tggacaaacc
     8101 gaagcctcgc cagtcattac gcaaacgaga gcaaatgatt ccttcataag aagagtcgaa
     8161 acaaccggcc gcgccctgcc acatactgag gtgaaaattg tagaacctgg gacatgtcaa
     8221 gaagttcaaa gaggcatgca gggagagctg tgcacccgtg gctatcacgt catgaaaggc
     8281 tattataaag acaaagaagc gaccagaaaa gcaatcaatc atgacggatg gctgtttacc
     8341 ggagatcttg ctgtcatgga tgaagacgga tactgccgca tcaccggaag attaaaagat
     8401 atgctcatca gaggcggcga gaacatttat ccgcgggaaa ttgaagaatt tttataccgg
     8461 catcccgctg ttttagatgt acaggtcgtt ggtgtgcctg acgccaaatt cggggaggaa
     8521 gctgcagcct ggattaaact gaaagacggt aaaagcgttt cacctgatga gcttaaagcc
     8581 tattgcaaag ggaaaatcgc ccgccacaaa attccgcgtt atgttatttt tacggatgac
     8641 tatccgatga cggcctcagg caaaattcaa aaatataaac tgcgagaaaa aacgattgaa
     8701 atgttcaacc tatcatcaag tcaatgaggt gaaatcatgt ttacaaaagt actgatcgcc
     8761 aaccgcggag aaattgcaat gagaattatc cgaacatgca gccgtctcgg cattaaaacg
     8821 gttgcggttt attcagaagc cgacaaggac gcgctccata caaaagccgc tacagaggct
     8881 tatttgatcg gagaatcgag agtcagtgaa agttatttaa atatagagag aatcataaag
     8941 acggcgaaaa aagcaaatgc cgacgcgatc cacccgggat atggattgtt atcagaaaac
     9001 agtcggttcg ctgaacgctg caagcaagaa aacatcgtgt ttatcggacc ttcccctgat
     9061 atcatcgcaa agatgggcag caaaattgaa gcgcgaaaag caatggaggc tgcaggtgtc
     9121 cctgtggtac cgggcgtttc tgaatccctc ggagatatag aggcagcctg ccgcaccgca
     9181 tgtcaaatcg gctatcctgt catgctgaaa gcttcagcgg gcggaggggg catcggaatg
     9241 cagcgtgttg aaaatgaaga agcattaaaa aaagcgtacg agggaaacaa aaagcgcgca
     9301 gcagattttt tcggtgacgg gtcgatgtat atagaaaaag ttattgaaca tgcgcgtcac
     9361 atcgaggttc agcttttggc tgatcaacac ggccatacag tacatctgtt tgaacgtgat
     9421 tgctctgttc agaggcgcca ccaaaaagtc attgaagaag caccgtctcc atttgtagac
     9481 gatgaactaa gaatgaagat tgggcaaaca gcggtaaaag cagcaaaggc aatcggctat
     9541 acgaacgcag gcaccatcga attcatagtt gaccagaagc aaaattttta tttcctcgaa
     9601 atgaatacga gactgcaagt tgaacacccc gtgactgaag aaataacagg cctggactta
     9661 gttgagcagc agctgcggat tgctgcgggc catacactca cattctccca aaaagacatc
     9721 caacggaacg ggcatgcgat agaggttcga atatacgcgg aagatcccaa gaccttcttc
     9781 ccgtcaccag gtacgatcac tgcgttttca cttcctgacc aaaaaggagt cagacacgaa
     9841 tgtgcggtag caaaagacag caccgttacc cctttttatg acccgatgat cgctaagatg
     9901 attgtcaaag gccaaaccag aacagaagca attgaaaaac tagagacatc gcttcgcgac
     9961 tatcgtgtag agggaatcaa aacaaatctt ccgcttctca tacaggctgc ggcaacaaag
    10021 gcatttaaag aaggggatgt cacgactgac tttttgaaac aacacctata aaggaggcag
    10081 ttgtcatgac ggttagcata caaatggcag gaaacctgtg gaaagtccac gtcaaagccg
    10141 gcgaccaaat cgaaaagggc caggaggtag ccattttgga atcgatgaaa atggaaatcc
    10201 cgatcgttgc agatagaagc ggaatcgtaa aagaagtcaa aaaaaatgaa ggagactttg
    10261 taaatgaagg agacgtactg ctcgaactga gcaattccac tcaataattt ggaggaagac
    10321 catgtcatat cctaaaaaag tgaaaatcaa agaagtcggc ccgcgtgacg gcttacaaaa
    10381 cgagcccgta tggatcgcaa cagaggataa aataacctgg atcaaccagc tttcccggac
    10441 agggctttcg tatattgaaa tcacatcctt cgttcacccg aaatggattc cggcgcttcg
    10501 agatgctatc gacgtagcaa aaggcatcga ccgtttaaaa ggggtaacgt acgcggcact
    10561 tgtcccgaat caaagaggat tggagaatgc gcttgaagga ggcattaacg aggcttgcgt
    10621 ttttatgtcc gccagcgaga cgcacaacag aaaaaacatc aataaatcca cttctgaatc
    10681 ccttcatata ctcaaacaag taaacaacga cgcacaaaaa gcaaacctca caacaagagc
    10741 ctacctctcg actgttttcg gctgtccgta cgaaaaagat gtccccattg aacaagtcat
    10801 tcgcctttca gaagctctat ttgaatttgg gatttctgaa ctttcgcttg gagatacgat
    10861 tggagcggct aatcccgccc aagtggaaac tgtacttgaa gctcttttgg cacgattccc
    10921 ggctaatcaa attgccttgc attttcatga tacgagagga accgctctgg ccaacatggt
    10981 cacagcactc caaatgggca tcacggtgtt tgacggctcg gcaggcgggc ttgggggatg
    11041 cccatatgcg ccaggttcat caggaaacgc cgcaactgag gatatcgtgt acatgcttga
    11101 acagatggat atcaaaacaa atgtaaagct agaaaaactg ctatctgcgg ccaaatggat
    11161 agaagaaaaa atgggcaaac cgctgccgag cagaaattta caggtgttta aatcatcttg
    11221 ataaaaggga ggacgcatac aatgggagac tctattcttt ttactgttaa aaatgaacat
    11281 atggcgttga tcacctttaa caggcctcag gcagcaaatg ctctttcagc ggaaatgctt
    11341 agaaacctgc aaatgattct tcaggaaatt gaattcaact caaacatccg ctgcgtcatc
    11401 ctcacaggca ccggtgaaaa agcgttttgt gcaggggcag acctaaagga acggataaaa
    11461 ctgaaagaag atcaggttct ggaaagtgta tctctcattc aaagaacggc ggctttactt
    11521 gatgccttgc cgcagccggt catagctgcg ataaatggaa gcgcattagg cggcggacta
    11581 gaattggcat tggcatgcga ccttcgaatc gcagctgaat cagctgtgct gggacttccg
    11641 gaaacagggt tagctattat cccgggcgct ggagggaccc aaaggctgcc ccggctgatt
    11701 ggcagaggaa aagcaaaaga attcatttat acaggcagac gcgtgaccgc acacgaagca
    11761 aaagaaatcg gccttgtaga gcatgtcacg gctccttgtg accttatgcc aaaagcagag
    11821 gaactggccg cagccatttc tgccaacggg ccgatcgctg tccgtcaggc taaatttgca
    11881 atcaataaag gattggagac agatctcgct acaggccttg cgattgaaca aaaagcgtat
    11941 gaacaaacca tcccgacaaa agacaggaga gaagggcttc aggcctttca agaaaaaaga
    12001 cgggccgtat acaagggaat ataaaaggga ggcaatgctc atggattatg aaaaggaacg
    12061 aacagaacgg gctgaacgga ttcgaaaagg cggagcggaa aagtatcatc aaggcaatcg
    12121 ggaaaaaggc aagctctttg tcagagagcg gctttccctt ctctttgacg atgacattga
    12181 gctagaagac gctttttttg cggaatgtat gtcagacggg cttcccgctg acggagttgt
    12241 aaccggtatc ggcaaaatcg gcggccaaac tgtttgcgtc atggcgaatg attcaacagt
    12301 gaaagcgggg tcatggggag ctaaaacagt tgaaaaaatc atcagaattc aagaaaccgc
    12361 ggaaaaatta aactgtccgc tcatttattt agtcgattcg gcaggcgccc gaattaccga
    12421 ccaaatcaat gtctttccag ggagacgcgg tgcaggaaga attttttaca atcaagtcaa
    12481 attatcggga cgcattccgc aaatctgtct gcttttcgga ccatctgcgg caggtggcgc
    12541 ttatattccg gccttctgtg atatcgtcgt tatggtagac ggtaacgcct ccatgtattt
    12601 aggctcgcca aggatggcgg aaatggttat tggagaaaaa gtgtctcttg aagaaatggg
    12661 tggcgcccgt atgcattgct caatctccgg ctgcggagat attcttgcag aaactgaaga
    12721 agaagccata cagctggcgc gggcttattt gtcttacttt ccggcaaatt ttcaagaaaa
    12781 agcgcccatt catgagaaac gcccgccaaa acacttcaaa actccgcttg ccgacgtcat
    12841 tccgcaaaat caaaacgcac cttttgatat gcatgagctg attgagcggg tcatagatga
    12901 agactcattt tttgagatca aagccttatt tgcaccggaa ttattgacgg gcctcgcacg
    12961 aatccacgga cagcctgtcg gcattgttgc aaaccagccg aaggtaaaag gaggcgtctt
    13021 attccacgat tcagcagaca aagcggctaa gtttattacc ttatgtgacg cttttcatat
    13081 cccattgctg ttcttagccg atatccccgg ttttatgatt ggcacaaaag tagaacaggc
    13141 tgggattatc agacacggag cgaaaatgat ttctgcgatg tcagaggcaa ctgttccaaa
    13201 actctctgtc attgtccgaa aagcttacgg ggcggggttg tatgcaatgg cagggccggc
    13261 atttgaaccg gattgctgtc tagcgctccc aaccgcccaa atcgccgtca tgggccctga
    13321 ggcagctgta aacgctgtct acgctaaaaa aatcgccgag ctgccagaag aagagagagc
    13381 cgcatttatc agcagcaaac gggaggaata caaagaggac atcaatatct accgtctggc
    13441 ttcagaaatg atcattgatg ctgttatccc agccaattcg ctgcgtgatg agctggccaa
    13501 acggctcaag gcatacatga caaaggaaat gacatttacc aatcgaaagc atccggttta
    13561 tccggtgtaa aagcaagaac ttaggagcgc aaaaaaagcg ctcctttata tatttacaat
    13621 aacaacatta tgtcaactaa ttaccattgc ataaaacgct tggtttttta gaatagtaaa
    13681 taaaggctgc cgcacctcta gcggcaattg tcagtttatc ataaaaaggg gcctacatta
    13741 tgtatcattt atattcacat aacgacttgg acggagtagg atgcggaatc gtagcaaaat
    13801 tggcgttcgg aaaagacgta gagatccggt ataactctgt caacggctta aacgcacagg
    13861 tgcagtactt tttagaaaaa gcgaaggaga gcaacagaca ggacgcgtta ttcatcaccg
    13921 atctcgccgt caatgaagaa aacgaagaga gattgaatga gtatgttcat gcagggggca
    13981 aagtgaagct cattgaccat cataaaacag cccttcattt gaatgagcat gaatggggat
    14041 ttgtccaggt ggaatacgat gatggaaggc tcacatccgc gacatcgctt ttatatggct
    14101 atctcgttga aaatggcttc atgaaaccga caaacgcctt agatcaattc acagagctcg
    14161 tccgccaata cgatacatgg gagtgggagc ggtacgatca aaaacaggca aagcggctta
    14221 atgatctttt ctttttgctg tcaatcgatg aatttgaagc aaaaatgatc cagcgccttt
    14281 ccgcgcatga cgaatttttc ttcgatgatt ttgaagaaaa actgcttgat ttagaagacg
    14341 aaaaaatcga gcgctacctc cgcagaaaga aaagggaaat ggtacaaacc tttgttcacg
    14401 aacactgtgt aggcatcgtt cacgctgaat cgtaccattc agagctgggg aacaggctag
    14461 gtaaagataa cccgcacctc gattacattg cgattttgag tatggggtca aaacgagtca
    14521 gtctccgcac cattcatgat cacatcgatg tgtcagaaat cgccggccga tatggcggcg
    14581 gagggcatgc aaaagcgtcc ggctgttcaa taaccgatga agtattcgag ttgtttgtag
    14641 ctgaagcttt ccgcattgat cctgtacggc cggatgcttt ccgtaacatc tataatctaa
    14701 agggatctgc gaatggatca ttatatgaaa atcgagcaca aatgagattt tttcttttcc
    14761 ctttagacaa cgaatggaat attcaaatta acggagaaac ccaagacgaa acattcgcag
    14821 cgtttgaaga ggcagaatgg tttattaaga gaaattatgc cgcatcgctc gtgcgggatg
    14881 aagtgtttgt cgcattttta gcggagaatc tgaagctggc aaatcaacat cggaagtaaa
    14941 aaaatatgca taggggagcg tcagtcaccc ctatgcatat ctgctagcta tcgtttaaat
    15001 atggctgtac gtttcttaat cacaaaataa agggctatca cgacaacagc caatatcata
    15061 atcggtgttg tataagtgcc tgctatattc tcaacatcat cccactggct tcctagctgt
    15121 atgcctaaat aaacaaacag aatagaccat ggaatgatag caagcacagt cagtaccaca
    15181 aatttgagaa aaggcattct ggcaatacct gccggaatgg atatggcatg tctgacaacc
    15241 ggtataaaac gagccgagaa g
//
