LOCUS       c00135_gnlPro..        14376 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFNFGPLJ_183.
ACCESSION   c00135_gnlPro..
VERSION     c00135_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 03:29:41
            Original ID  :: gnl|Prokka|HFNFGPLJ_183
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14376
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14376
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1084:4376]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1085..4376
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14376
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14376
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1085..2809
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg135_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.9e-54, bitscore:
                     174.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTNVQVDSASAKCTQTMSGALMLIESLKKEKVEMIFGYPGGAVL
                     PIYDKLYNSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADILGITMPVTKHSYQVRQPEDLPRIIKEAFHIAT
                     TGRPGPVLIDIPKDVATIEGEFSYDHEMNLPGYQPTTEPNYLQIRKLVEAVSSAKKPVI
                     LAGAGVLHGKASEELKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMAL
                     HECDLLISIGARFDDRVTGNLKHFARNAKIAHIDIDPAEIGKIMKTQIPVVGDSKIVLQ
                     ELIKQDGKQSDSSEWKKQLAEWKEEYPLWYVDNEEEGFKPQKLIEYIHQFTKGEAIVAT
                     DVGQHQMWSAQFYPFQKADKWVTSGGLGTMGFGLPAAIGAQLAEKDATVVAVVGDGGFQ
                     MTLQELDVIRELNLPVKVVILNNACLGMVRQWQEIFYEERYSESKFASQPDFVKLSEAY
                     GIKGIRISSEAEAKVKLEEALTSREPVVIDVRVASEEKVFPMVAPGKGLHEMVGVKP"
     CDS             2806..3324
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg135_2"
                     /sec_met_domain="ALS_ss_C (E-value: 9e-32, bitscore: 101.0,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSR
                     ITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSTRTEING
                     IIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKA
                     SSNKTISIV"
     CDS             3348..4376
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg135_3"
                     /sec_met_domain="IlvN (E-value: 4.5e-78, bitscore: 252.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.6e-68, bitscore: 221.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIV
                     GVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKSLV
                     FAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEARDK
                     ALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDI
                     QNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVSVA
                     QN"
     CDS             4363..5919
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg135_4"
                     /sec_met_domain="HMGL-like (E-value: 5.2e-100, bitscore:
                     326.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRKINFFDTTLRDGEQSPGVNLNTQEKLAIAKQLERLGADIIEAG
                     FPASSRGDFLAVQEIARTIKNCSVTGLARCVKGDIDAAWEALKDGAYPRIHVFIATSDI
                     HLKHKLKMTREQVIERAVEMVTYAKERFPVVQWSAEDACRTELPFLAEIVEKVIDAGAS
                     VINLPDTVGYLAPAEYGNIFKYMKENVPNIHKAKLSAHCHDDLGMAVANSLAAIENGAD
                     QIECAVNGIGERAGNAALEEIAVALHTRKDFYQVETGITLNEIKRTSDLVSKLTGMAVP
                     RNKAVVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRL
                     TALGFQFDSEEINKFFTMFKELTEKKKEITDEDLVSLILEEKVTDRKIGYEFLSLQVHY
                     GTSQVPTATLSLKNQENAELIQEAATGAGSVEAIYNTLERCIDKDVELLDYRIQSNRKG
                     EDAFAQVYVRVLVNGKESAGRGIAQDVLEASAKAYLNAVNRQLVFQSNMSGLKNHTAVG
                     S"
     CDS             5940..7037
                     /locus_tag="ctg135_5"
                     /transl_table=11
                     /translation="LKKRIALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIGG
                     AAIDEHHNPLPEETVAACKNADAILLGAVGGPKWDQNPSELRPEKGLLSIRKQLDLFAN
                     LRPVKVFESLSDASPLKKEYIDNVDFVIVRELTGGLYFGQPSKRYVNTEGEQEAVDTLF
                     YKRTEIERVIREGFKMAAARKGKVTSVDKANVLESSRLWREVAEDVAKEFPDVKLEHML
                     VDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLFEPVH
                     GSAPDIAGKGVANPFAAILSAAMLLRTSFGLEEEAKAVEDAVNKVLASGKRTKDLARGE
                     EFSSTQAITEEVKAAIMSENTISNV"
     CDS             7087..8505
                     /locus_tag="ctg135_6"
                     /transl_table=11
                     /translation="MMPRTIIEKIWDQHIVKHGEGKPDLLYIDLHLIHEVTSPQAFEGL
                     RQKGRKVRRPQNTFATMDHNIPTVNRFEIKDEVAKRQVTALERNCEEFGVRLADLHSVD
                     QGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRP
                     KTLEVRVDGTLQKGVTAKDVILAVIGKYGVKFGTGYVIEYTGEVFRNMTMDERMTVCNM
                     SIEAGARAGLIAPDEVTFEYCKNRKYTPKGEEFDKAVEEWKALRTDPGAVYDKSIVLDG
                     NKISPMVTWGINPGMVLPVDSEVPAPESFSAEDDKKEAIRAYEYMGLTPHQKIEDIKVE
                     HVFIGSCTNSRMTDLRQAADMIKGKKVADSVRAIVVPGSQSVKLQAEKEGLDQIFLEAG
                     FEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGH
                     FVDVRKFYQEKTVV"
     CDS             8518..9117
                     /locus_tag="ctg135_7"
                     /transl_table=11
                     /translation="MEPLKSHTGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFD
                     WRYDANGEPNPEFELNQPVYQGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPSFA
                     DIFHQNCFKNGMLPIRMPYDNWKQLVGQYENQSLQMTVDLEKQLIHDSEGNQISFEVDP
                     HWKEMLINGYDEISLTLLLEDEIKQFESQRSSWLQA"
     CDS             9237..10241
                     /locus_tag="ctg135_8"
                     /transl_table=11
                     /translation="MTHDKKNAKIIPFPHLKDRLVEKGMSSLKEKKYQEALELFSEAMK
                     YDDTESDLHLGMAICFLELGELEEAKSVCEKMLKEGYGHYFTVLQVYMTILIQLKKYEE
                     VKSTIEAVLEENQLPAESAEQFYKLLDFSRKMTDPDREDEAWAEEYEDTIDTEKVLASP
                     EEQMNLIHSLKDRNVAKYTGLLKTILQDPSAHPIIKTMIVMLLTEHEYSKPVHISKFGE
                     SLTIEPSEIVPPDAAPILHRVLRVLDETLGNENPTLYAAVEELWRRHLYVLYPFQPKLL
                     SADLWAAALHKVGYEMHGIEIESEELHMMYEFTDRELDEACTMLKDIEEISYL"
     CDS             10469..11743
                     /locus_tag="ctg135_9"
                     /transl_table=11
                     /translation="MSVKWEKQEGNEGVLTVEVDAETFKTALDDAFKKVVKQVSIPGFR
                     KGKIPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGESL
                     IFTAKVTVKPEVKLGDYKGLGIEKDDTTVTDEDVQNELKALQERQAELVVKEEGAVEEG
                     NTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEDQLVGLEAGAEKDVEVTFPEE
                     YHAEDLAGKPAVFKVKIHEIKAKELPELDDEFAKDIDEEVETLAELTEKTKKRLEEAKE
                     NEADAKLREELVLKASENAEIDVPQAMVDTELDRMLKEFEQRLQMQGMNLELYTQFSGQ
                     DEAALKEQMKEDAEKRVKSNLTLEAIAKAENLEVSDEEVDAELTKMAEAYNMPVENIKQ
                     AIGSTDAMKEDLKVRKAIDFLVENR"
     CDS             11919..13277
                     /locus_tag="ctg135_10"
                     /transl_table=11
                     /translation="MVKCNTYSFVSRIIFFCSAGKRKSETRLRGERMFKFNEEKGQLKC
                     SFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILN
                     EYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLAR
                     ILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKS
                     ENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFD
                     GIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASL
                     EKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLR
                     SIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQDKTSA"
ORIGIN
        1 atactgaacc cgccgctatg gccgctgaag ccagtgcctg aaaattgctg cccgaaaaaa
       61 tctgaagtgt atggataaga ggagtacata gcagagggag tggttaacgg gctatatgcc
      121 tggctgaacg gctgtccgta tccgtagcct ccaaatggct gatggctttg ctggtaaaag
      181 ggagggacag caggataata ctgctgcgga aagctcggga agcttggaaa gcctgcaggg
      241 aatccttgca tgtctgctaa tgatttattc atcgtatcac cttttctttg caagatacca
      301 ttaatgtatg ccggggaata atagtggtgc ctatccgaac ttgaaatgga ttgcaagttg
      361 atctgtcaga ctcaatccat atacgaacca tagcgtgtta taaaatctta catgtttata
      421 taaaattaaa taattctggt gtattcttga tagattaata aaaaaattat aaaaactttt
      481 aacatttgca attccttttg taccaataat gaaagcgtat acaatataga ttgattaatc
      541 aaaattgtct aataatttta aaaaatgctg ttgacactgc gtccaaagcg gcgtaatatg
      601 agttcaacaa aagataaacg caagcttcac aagcgaaaat catcgcagta tgattctaaa
      661 aaaatgaaaa acaaacgacc ttcttgaaca gctggaaagc cgttctgaag ggtgaatatg
      721 aaaagcgcag atgaggataa gtagccttga taaagctttc cacagagaac cgggttagct
      781 gagaaccggt gaagctttac aaggtgaact cgcctcagag tgccagtctg aaatgacagt
      841 aggacttggc cgggtgaact tgattcactc gttactaaag cggatagaaa tatccatgag
      901 acggccgact aaggccgtaa acaagggtgg taccgcggaa agaaaagcct tttcgcccct
      961 tttagctatc gcagttactg cgcggctgat tgtgggtgga agggcttttt ttattgaata
     1021 atcagctatc tagctaataa aaagatgatc tttaaaggat gaaaatccaa aaggaggaac
     1081 taaaatgagg actaatgtac aggtggattc agcatctgcc aaatgtacac agacgatgag
     1141 cggagcatta atgctgattg aatcattaaa aaaagagaaa gtagaaatga ttttcggtta
     1201 tccgggcggg gctgtgcttc cgatttacga taagctatac aattcagggt tggtacatat
     1261 ccttccccgt cacgaacaag gagcaattca tgcagcggag ggatacgcaa gggtctccgg
     1321 aaaaccgggt gtcgtcattg ccacgtcagg gccgggagcg acaaaccttg ttacaggcct
     1381 tgctgatgcc atgattgatt cattgccgtt agttgtcttt acagggcagg tagcaacctc
     1441 tgtaatcggg agcgatgcat ttcaggaagc agacatttta gggattacga tgccagtaac
     1501 aaaacacagc taccaggttc gccagccgga agatctgccg cgcatcatta aagaagcgtt
     1561 ccatattgca acaactggaa gacccggacc tgtattgatt gatattccga aagatgtagc
     1621 aacaattgaa ggagaattca gctacgatca tgagatgaat ctcccgggat accagccgac
     1681 aacagagccg aattatttgc agatccgcaa gcttgtggaa gccgtgagca gtgcgaaaaa
     1741 accggtgatc ctggcgggtg cgggcgtatt gcatggaaaa gcgtcagaag aattaaaaaa
     1801 ttatgctgaa cagcagcaaa tccctgtggc acacaccctt ttggggctcg gaggcttccc
     1861 ggctgaccat ccgcttttcc tagggatggc gggaatgcac ggtacttata cagccaatat
     1921 ggctcttcat gaatgtgatc tattaatcag tatcggcgcc cgttttgatg accgtgtcac
     1981 aggaaacctg aaacactttg ccagaaacgc aaagatagcc cacatcgata ttgatccagc
     2041 tgaaatcgga aaaatcatga aaacacagat tcctgtagtc ggagacagca aaattgtcct
     2101 gcaggagctg atcaaacaag acggcaaaca aagcgattca agcgaatgga aaaaacagct
     2161 cgccgaatgg aaagaagagt atccgctctg gtatgtagat aatgaagaag aaggttttaa
     2221 acctcagaaa ttgattgaat atattcatca atttacaaaa ggagaggcca ttgtcgcaac
     2281 agatgtaggc cagcatcaaa tgtggtcagc gcaattttat ccgttccaaa aagcagataa
     2341 atgggtcacg tcaggcggac ttggaacgat gggattcggt cttccggcgg cgatcggcgc
     2401 acagctggcc gaaaaagatg ctactgttgt cgcggttgtc ggagacggcg gattccaaat
     2461 gacgcttcaa gaactcgatg ttattcgcga attaaatctt ccggtcaagg tagtgatttt
     2521 aaataacgct tgtctcggaa tggtcagaca gtggcaggaa attttctatg aagaacgtta
     2581 ttcagaatct aaattcgctt ctcagcctga cttcgtcaaa ttgtccgaag catacggcat
     2641 taaaggcatc agaatttcat cagaagcgga agcaaaggta aagctggaag aggcattaac
     2701 atcaagagaa cctgttgtca ttgacgtgcg ggttgccagc gaagaaaaag tattcccgat
     2761 ggtggctccg gggaaagggc tgcatgaaat ggtgggggtg aaaccttgaa aagaattatc
     2821 acattgactg tggtgaaccg ctccggggtg ttaaaccgga tcaccggtct attcacaaaa
     2881 aggcattaca acattgaaag cattacagtt ggacacacag aaacagccgg cgtttccaga
     2941 atcaccttcg tcgttcatgt tgaaggagaa aatgatgttg aacagttaac gaaacagctc
     3001 aacaaacaga ttgatgtact gaaagtcaca gacatcacaa atcaatcgat tgtccagagg
     3061 gagctggcct taatcaaggt tgtctccgca ccttcaacga gaacagagat taatggaatc
     3121 atagaaccgt ttagagcctc tgtcgttgat gtcagcagag acagcatcgt tgttcaggtg
     3181 acaggcgaat ctaacaaaat tgaagcgctt attgaattgt tgaaacctta tggcattaaa
     3241 gaaatcgcga gaacaggtac aacggctttt gcgaggggta cccagcaaaa ggcgtcatcc
     3301 aataaaacaa tatctattgt ataaaacata acaagggaga gattgaaatg gtaaaagtat
     3361 attataacgg tgatatcaaa gagaacgtat tggcaggcaa aacagtagcg gttatcggat
     3421 acggttcgca aggccacgca catgccctga accttaaaga aagcggagta gacgtgatcg
     3481 tcggtgttag acaaggaaaa tctttcacgc aagcccaaga agacggacat aaagtttttt
     3541 cagtaaaaga agcggcagcc caagctgaaa tcatcatggt tctgcttcct gatgaacagc
     3601 agcaaaaagt atacgaagct gaaatcaaag atgaattgac agcaggaaaa tcattagtat
     3661 ttgctcacgg atttaacgtg catttccatc aaattgttcc tccggcggat gttgatgtat
     3721 tcttggtagc gcctaaaggt ccgggacact tggtcagaag aacatatgag caaggagccg
     3781 gcgtacctgc attgttcgca atctatcaag atgtgactgg agaagcaaga gacaaagctc
     3841 tcgcatatgc aaaaggaatc ggtggcgcaa gagcgggagt attagaaacg acatttaaag
     3901 aagaaacaga aacagatttg ttcggtgagc aagcggttct ttgcggcgga ttaagcgcgc
     3961 ttgtcaaagc aggatttgaa acattaactg aagcaggtta tcagcctgaa cttgcatact
     4021 tcgagtgtct gcatgagctg aaattaatcg tagaccttat gtacgaagaa ggacttgcag
     4081 gaatgagata ttcaatttct gacacagcac agtggggaga tttcgtatca ggccctcgcg
     4141 ttgtggatgc taaagtaaaa gaatcgatga aagaagtatt aaaagatatc caaaacggta
     4201 cattcgcaaa agaatggatc gtcgaaaacc aagtaaaccg tcctcgtttc aacgctatca
     4261 atgcgagcga gaacgaacat caaatcgaag tagtgggaag aaagcttcgt gaaatgatgc
     4321 cgtttgtgaa acaaggcaag aagaaggaag cggtggtctc cgttgcgcaa aattaatttt
     4381 ttcgatacga cgcttcgtga tggtgaacag tcccctggag tgaacttgaa tacacaggag
     4441 aaacttgcca tagctaagca gctcgaaaga ctcggggcag atatcattga agcgggattt
     4501 cccgcttcgt cccgaggtga ctttttagct gttcaggaaa tcgctagaac cattaaaaat
     4561 tgttcagtga ctggtctggc ccgttgtgta aaaggtgata ttgatgctgc ttgggaagcg
     4621 ttaaaggatg gtgcttaccc gagaattcat gtttttatcg ccacatcgga cattcatttg
     4681 aaacacaagc tgaaaatgac acgtgagcaa gtcattgaaa gagcagttga aatggtgaca
     4741 tacgcaaaag aacgttttcc ggttgtgcaa tggtcagctg aagatgcctg ccgcactgag
     4801 ctgccgtttc tggcagaaat cgtcgagaaa gtgattgacg caggcgccag tgttatcaat
     4861 cttccagaca ctgtcggcta cctggctcca gcggaatacg gaaatatctt taaatatatg
     4921 aaggaaaacg ttccgaacat tcacaaagca aagctttcag cccactgtca tgatgattta
     4981 ggaatggcag ttgcaaactc tcttgctgcg attgaaaatg gcgctgatca aatcgaatgc
     5041 gctgtgaacg ggatcggtga aagagccgga aacgcggcat tagaggaaat tgccgtagcc
     5101 ctccatacca gaaaagattt ctaccaagtc gaaacaggca ttacactgaa cgagattaag
     5161 agaacaagtg atttagtaag caaactgaca ggcatggctg tcccacgcaa caaagcggtt
     5221 gttggagata atgcatttgc tcatgaatca ggcatccatc aggacggctt tttaaaggaa
     5281 aaatcgactt atgaaattat ttcaccggag cttgtcggcg taaccgcaga tgcgcttgtc
     5341 ctaggtaaac attccggacg ccacgcattt aaagaccggc tgactgcttt aggattccaa
     5401 tttgacagtg aagagattaa taaattcttt acgatgttca aagagttgac tgagaagaaa
     5461 aaagaaatca ctgatgagga tcttgtttct cttattttag aagaaaaagt aacagatcgc
     5521 aagattgggt atgaatttct ttctctgcaa gtacattacg gaacaagtca ggtccctacg
     5581 gctactcttt cgttgaaaaa tcaagaaaat gcagagctta ttcaggaagc tgcaactgga
     5641 gctggaagtg tggaagcaat ctacaatacg cttgagcgct gcatcgataa ggacgtggag
     5701 cttttagact accgcattca gtctaacaga aaaggcgaag atgcatttgc ccaggtgtat
     5761 gtaagagttt tggtgaacgg aaaagaatca gcaggtcggg gcatagcgca agacgtatta
     5821 gaagcatcag cgaaagccta tttgaacgca gtcaaccgtc aattggtttt ccagtcgaat
     5881 atgagcggat tgaaaaacca cacagctgtc ggatcataaa agaaaggaga acggttaact
     5941 tgaagaaacg tattgctcta ttgcccggag acgggatcgg ccctgaagta ttagaatcag
     6001 cgacagacgt actgaaaagt gttgccgaac gctttaacca tgaatttgaa tttgaatatg
     6061 gcctgattgg aggggcggct attgatgaac atcataaccc cctcccggag gaaaccgttg
     6121 ctgcttgtaa aaatgcagac gcgatattgc ttggtgctgt cggcggaccg aaatgggatc
     6181 aaaatccttc ggaactgaga ccggaaaaag ggctgctcag catcagaaaa cagcttgatt
     6241 tgtttgcgaa tttacggcct gtgaaggtat ttgaaagcct ttctgatgct tcgcctttga
     6301 aaaaagaata tatagataat gttgatttcg ttatcgttcg tgaactcaca ggcggcttgt
     6361 atttcggcca gccgagcaaa cgctatgtaa acactgaagg tgagcaggaa gcagtagata
     6421 cactgtttta taagcgaacg gaaattgaac gagtgatcag agagggcttc aaaatggcgg
     6481 cagccagaaa aggcaaagtg acctctgtag ataaagcgaa tgttcttgaa tcaagccggc
     6541 tgtggcgtga agtggctgag gacgttgcga aagaatttcc tgatgtgaag cttgagcaca
     6601 tgcttgtgga taacgcggcc atgcagctaa tctatgcacc gaatcaattt gatgtcgttg
     6661 tgactgaaaa tatgttcggt gatattttaa gcgatgaagc gtccatgctt acaggctcgc
     6721 tcggaatgct cccgtcagcc agcctatcaa gctctggtct tcatctgttt gaacctgttc
     6781 atggctccgc gcctgatatt gccggtaaag gggtggcaaa tccgttcgca gccatattgt
     6841 cagcggcaat gcttttgaga acatctttcg ggcttgaaga ggaagcgaaa gctgtagaag
     6901 atgcggtaaa caaagtcttg gcttctggga aaagaacaaa agatttggca cggggtgaag
     6961 agttcagcag cactcaggcc attacagagg aagttaaggc agcaatcatg agtgaaaata
     7021 caatttctaa tgtgtgacag cttacgttaa gcggtcttag ctctaggtag agggaggaaa
     7081 taaaagatga tgcctcgaac aatcatcgaa aagatttggg atcagcatat tgtaaaacat
     7141 ggtgagggaa agccggatct tctctatatt gatttgcacc tcattcatga ggtgacgtct
     7201 cctcaggcat ttgaaggctt gagacaaaag ggaagaaagg tcagaagacc ccaaaacaca
     7261 tttgcgacaa tggaccacaa catcccgact gtcaatcgtt ttgagataaa ggatgaagtt
     7321 gcgaaacgcc aggtaacggc gcttgaaaga aactgtgagg aatttggcgt gcgccttgcc
     7381 gatcttcaca gtgtggatca agggattgtc catgtcgtcg gacctgaact gggcttaacg
     7441 cttccaggga aaacgattgt gtgcggggac agtcatacat caacacatgg tgctttcggc
     7501 gctcttgcat ttgggatcgg gacgagtgaa gttgaacatg tcctttccac acagacactt
     7561 tggcagcagc gtccaaaaac acttgaagtg cgcgtagatg gaacgcttca aaaaggggta
     7621 acggcaaagg atgtcatcct tgctgtcatc ggcaaatacg gtgtgaaatt cggcacaggc
     7681 tacgtcattg aatacactgg ggaagtattc agaaatatga cgatggatga acgaatgact
     7741 gtttgtaaca tgtcaattga agcaggagca agagcaggtt tgattgcacc tgacgaggtg
     7801 acgtttgaat attgcaaaaa tcgcaagtac acgccaaaag gcgaagaatt tgacaaggcc
     7861 gtagaggaat ggaaggcgct gcgcacagac ccgggcgctg tttacgataa atctatcgtc
     7921 cttgacggca acaaaatttc ccctatggtg acatggggca ttaaccctgg aatggttctt
     7981 cctgtcgatt ctgaagttcc tgcgccggaa agcttttctg cagaagatga taaaaaagaa
     8041 gcgattcgcg cttatgaata tatgggactg actcctcatc agaaaattga agacattaaa
     8101 gtggagcacg tatttatcgg ttcctgcaca aattcccgca tgactgacct tcgacaggct
     8161 gctgacatga tcaaagggaa gaaggtagct gacagcgtaa gggccatcgt cgtgcccgga
     8221 tcccaaagcg tgaagcttca ggctgaaaaa gaagggcttg accagatttt cttggaagct
     8281 ggatttgaat ggagagagtc aggctgcagc atgtgtttga gtatgaataa tgatgttgtt
     8341 cctgagggag agcgctgtgc atcaacctct aaccgcaact tcgagggcag acaaggaaaa
     8401 ggtgcaagaa cacatctcgt cagcccggcg atggctgcga tggctgccat tcacggacac
     8461 ttcgttgatg tcagaaagtt ttatcaggaa aaaacagttg tgtaaggagt gcgcgagatg
     8521 gaacctttga aatcacatac ggggaaagca gccgtattaa atcggatcaa tgtggataca
     8581 gaccagatta ttcctaagca atttttgaag aggattgaaa gaacaggcta cgggcgtttt
     8641 gcattctttg actggagata tgatgcgaat ggtgaaccga accctgaatt tgaattaaac
     8701 cagcctgttt atcaaggagc ttccatttta atagcaggag aaaacttcgg ctgcgggtca
     8761 tcgcgtgaac acgctccgtg ggcacttgat gattatgggt ttaaaattat tattgcaccg
     8821 tcatttgctg atattttcca tcagaactgc tttaaaaacg gtatgcttcc gatccgcatg
     8881 ccatatgaca attggaaaca gcttgtcggc cagtatgaaa accagtcatt gcaaatgaca
     8941 gttgaccttg aaaagcagct gattcatgat agtgaaggca atcaaatttc atttgaagtt
     9001 gatccgcatt ggaaagagat gctgatcaac ggatatgatg aaatttcatt aacgctgctg
     9061 ctggaagatg aaatcaagca atttgaatca caaagaagct cttggcttca agcctgaaaa
     9121 agcggccggt atttgtccgg cggctttttt ttgcctgatg aaacctttca tttcttgttt
     9181 ttgttcacag gtgttgatac acttgaacaa aataaatgcc tgaaaggaat ataggtatga
     9241 cgcatgacaa gaagaacgca aaaattattc cttttcctca tctgaaagac cgccttgtgg
     9301 aaaaggggat gtcatcacta aaggaaaaaa agtatcaaga agcgcttgaa ctgttttcag
     9361 aagcgatgaa atatgatgat actgaatccg atcttcactt agggatggcc atctgctttt
     9421 tagagctggg cgagctggaa gaggcaaaaa gcgtgtgcga gaagatgctc aaagaaggtt
     9481 atggccatta ttttacggtt ttgcaggtgt acatgaccat cttaattcag ctcaaaaaat
     9541 acgaggaagt caaaagcacc attgaagccg ttttggaaga aaatcagctg ccggcagaaa
     9601 gcgccgagca attttataag ctgctggatt tcagccggaa aatgaccgat ccggatcgtg
     9661 aggacgaggc ttgggccgaa gaatatgagg atacaattga caccgagaaa gtgctggcaa
     9721 gccctgagga gcaaatgaat ctcattcatt ccttaaaaga ccgtaacgta gcaaagtata
     9781 caggattgct caaaacaatc ctccaagacc cctcagccca cccgattatc aaaacgatga
     9841 ttgtcatgct gttgactgag catgagtaca gtaagcctgt acacattagt aaatttggcg
     9901 agtcgttgac aattgaaccg tctgagattg ttccgcctga tgccgcgccg attctgcacc
     9961 gtgttctcag ggtgctggat gagacacttg gaaatgaaaa tccaacctta tatgcagcag
    10021 tagaggaatt gtggagaaga catttgtacg ttttatatcc gttccagccg aaattgctgt
    10081 cggctgacct ttgggcggct gcccttcata aagtcggtta cgagatgcac gggattgaaa
    10141 ttgaaagcga agaacttcat atgatgtatg aatttaccga cagagaactc gatgaagctt
    10201 gcacaatgtt aaaagatatt gaagaaattt cttatttgta aatcgcgcca tatagttgaa
    10261 agcgctatgt gttatgttat aatatagtgg ttgtatttgt gtataacggg ttataagaaa
    10321 tacggttgga caggctttgc agttcattat taacatctat acataatgat tctgatcttt
    10381 ggcagctttg tttttgttgg acgaagccgt atgattgctt tagaatggaa gaccgacaca
    10441 acctgaatag atttttggag ggaaacacat gtctgtaaaa tgggaaaaac aagaaggcaa
    10501 cgaaggcgtt ttaacggttg aagttgatgc tgaaacgttt aaaacagcac ttgatgatgc
    10561 atttaaaaaa gtagtaaaac aagtttcaat tcctggattc cgtaaaggta aaattcctcg
    10621 cggattattc gaacagcgct ttggcgtaga agctctttac caagatgctt tggatattct
    10681 tcttcctgta gaatacccta aagcggttga agaagctgga atcgagcctg tagaccgtcc
    10741 tgaaatcgat gttgaaaaaa tcgaaaaagg cgaaagctta atcttcactg cgaaagtaac
    10801 agtaaaacct gaagtgaagc ttggcgacta caaaggctta ggcattgaaa aagacgacac
    10861 aactgtaact gacgaagatg ttcaaaacga actaaaagcg cttcaagagc gtcaagctga
    10921 gcttgttgta aaagaagaag gcgccgttga agaaggaaac acagttgttc ttgatttcga
    10981 aggattcgtt gacggcgaag ctttcgaagg cggaaaagct gaaaactact ctctagaagt
    11041 aggttctggt tcattcatcc ctggcttcga agatcaatta gttggccttg aagcaggtgc
    11101 tgagaaggat gttgaagtga cattccctga ggagtaccac gctgaagatc ttgcaggcaa
    11161 accagctgtg tttaaagtga aaattcacga aatcaaagcg aaagagcttc ctgagcttga
    11221 cgatgaattc gcaaaagata tcgatgaaga agtggaaaca cttgctgaat taactgaaaa
    11281 aacaaagaaa cgtttagaag aagcaaaaga aaacgaagct gacgctaaat tgcgtgaaga
    11341 gcttgttctg aaagcttctg aaaatgctga aattgatgtg cctcaagcaa tggtcgacac
    11401 tgagcttgac cgcatgctga aagaattcga acagcgtctg caaatgcaag gcatgaacct
    11461 tgagctttac actcaattct caggccaaga tgaagctgcg cttaaagagc aaatgaaaga
    11521 agatgctgaa aaacgcgtaa aatctaacct gactcttgag gcgattgcga aagcggaaaa
    11581 ccttgaagta tcagatgagg aagttgatgc tgagcttaca aaaatggctg aagcatacaa
    11641 catgcctgtt gaaaatatta aacaagccat cggttctact gacgcgatga aagaagattt
    11701 aaaagttcgc aaagcaattg attttcttgt agaaaaccgt taatatggtg cataataata
    11761 gtactaataa aacagggcgc gaatcattcg tgccttgttt tgtacaatta tgagttatct
    11821 ctttttcttg gggcaatata gttaatgcag ggctgttttt tgtcatacat atagaatgtg
    11881 caagtcagaa acacattgtt accgtctttt tggaaagtat ggtaaaatgc aatacatact
    11941 cgttcgtttc aagaatcatt ttcttttgct ctgccggtaa aagaaaaagt gagacaagat
    12001 taaggggtga aagaatgttt aaatttaacg aggaaaaagg acaattaaaa tgctcgttct
    12061 gtggaaaaac acaagatcag gttcgtaagc ttgtagctgg acctggtgta tatatatgtg
    12121 acgaatgtat cgaactctgc actgaaattg tagaggaaga actcggaaca gaagaagaag
    12181 tagaatttaa agacgtacca aagcctcagg aaattcgcga aattttgaat gaatatgtca
    12241 tcggccaaga tcaagcgaag aaatcacttg ctgttgctgt gtataaccac tataagcgca
    12301 ttaactccaa cagcaaagtt gatgatgttg agctttcaaa aagtaatatt tcattaatcg
    12361 gccctacggg aagcggtaaa acccttctgg cgcaaacatt ggctcgcatt ttaaatgtgc
    12421 cgtttgcgat tgcggacgct acatctttga ctgaagctgg atacgtgggt gaagatgtag
    12481 agaatattct cttgaagctc atccaagctg ctgattatga tgtggaaaaa gccgaaaaag
    12541 gcattatcta tattgatgaa atcgataaag tggctagaaa atctgaaaac ccgtctatca
    12601 cacgtgatgt gtcaggtgag ggtgtacagc aggcattgct taaaattctt gagggtacag
    12661 tggcaagcgt accgcctcaa ggtggacgta agcatcctca tcaagaattc attcaaattg
    12721 acacaacaaa tattttgttc atttgcggcg gagctttcga tggtatcgaa caaatcatca
    12781 aacgccgttt aggccaaaaa gtgattggat tcggtgccga caataaagct gctgatcttg
    12841 agaaagaaga tcttctttca aaagtgcttc cagaagattt gctccgtttc gggttaattc
    12901 ctgaatttat cggacgtctt ccggttattg caagccttga aaagcttgac gaagaagcat
    12961 tggttgcgat cttaacaaaa ccgaaaaacg ctcttgttaa gcaattcaag aaaatgcttg
    13021 agcttgacaa cgttgagctt gagtttgaag aagaagcgct ttctgaaatt gctaaaaaag
    13081 caattgaacg caagactgga gcacgcggac tccgttctat cattgaaggc atcatgcttg
    13141 atgtgatgtt tgagctgcct tctcgtgatg acattgaaaa atgtgtaatc accggggcaa
    13201 ctgtgacaca cggagagcct cctcgcctct tattaaaaga cggcactgag gtaagccaag
    13261 ataaaacatc tgcataaaga taagcacaaa cctcctgagt ggtaacactc aggaggtttt
    13321 tttgcatgca actcttccgg aaaaacgttt attcccgtct tctatgggag atactagcaa
    13381 tcagagagga atgaattgga tacataaatt gtttttcagg agggaccacc atgagttgga
    13441 cagggatcgc gttatttatt cagctgtttt ttgggatcat catcggtttg tatttttgga
    13501 atttgcttaa aaatcaaagg acacaaaagg tcacgataga taaagaatca aagaaggaaa
    13561 tggagcagct tcggaaaatg cgtgctatca gcttgtccga gccattatct gagaaggtcc
    13621 gccccaaaag ctttaaagat atcgtcggac aggaagacgg cattaaagca ttaaaggcgg
    13681 ctttatgcgg gccaaatcct cagcatgtga ttgtctatgg gccaccggga gttgggaaaa
    13741 cggctgctgc gcggcttgtg ttggaagaag caaaaaaaca taaacaatca ccgtttaaag
    13801 agcaggctgt ctttgtggaa ctcgatgcga caacagcccg ttttgatgaa agaggaattg
    13861 ccgatccgct catcggctct gtccatgacc cgatatatca aggggccgga gcgatgggac
    13921 aggctgggat tccgcagccg aagcagggag ctgtcaccca tgcccatggc ggtgtgctgt
    13981 ttattgatga aataggggag ctgcatccta ttcaaatgaa taaaatgctg aaggtgcttg
    14041 aggacagaaa agtcttttta gacagtgcgt attacagtga ggaaaataca caaattccga
    14101 atcatattca tgatattttt caaaatgggc tgccggctga ttttcgcttg attggcgcga
    14161 ccacgagaat gccaaacgaa attccgccag ctatcaggtc ccgctgtctg gaggtttttt
    14221 tccgcgagct tgaaaaggac gagctgaaaa ctgttgccaa aacagcagcg gataaaattg
    14281 aaaaaaatat ctccgaagaa ggcctagatc ttttgaccag ctacacacgg aacgggcggg
    14341 aagccgtcaa tatgattcaa atcgcagcgg ggatgg
//
