LOCUS       gnlProkkaMLHCIMPN_1     2357 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MLHCIMPN_1.
ACCESSION   gnlProkkaMLHCIMPN_1
VERSION     gnlProkkaMLHCIMPN_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:50:41
            Original ID  :: gnl|Prokka|MLHCIMPN_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2357
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2357
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:2357]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2357
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2357
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2357
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     aSDomain        complement(3..677)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.10E-74"
                     /label="ctg1_1_Condensation_LCL.1"
                     /locus_tag="ctg1_1"
                     /protein_end="785"
                     /protein_start="560"
                     /score="241.1"
                     /tool="antismash"
                     /translation="DTYPVSSAQKRMYVLQQLEDGGVGYNMPAVLELTGPLDRGRLEET
                     FRQLVERHESLRTSFETGPDGEPVQRIHDSVPFQLDEAESADAFVRPFCLEEAPLFRAA
                     LVKESDEHHLLLTDMHHIISDGVSVNTLIKEFGELYAGRSLAPMRLQYKDYAVWQRSFQ
                     EKEGYQKQEAYWLKRLEGELPVLELPADKPRPAVRSFAGGSVSCTLDAETASGLHRIAR
                     DHG"
     CDS             complement(3..2357)
                     /NRPS_PKS="Domain: AMP-binding (1-375). E-value: 6.6e-99.
                     Score: 323.1. Matches aSDomain:
                     nrpspksdomains_ctg1_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (477-545). E-value: 2.3e-25. Score:
                     80.5. Matches aSDomain: nrpspksdomains_ctg1_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (560-785). E-value:
                     4.1e-74. Score: 241.1. Matches aSDomain:
                     nrpspksdomains_ctg1_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     340.1; E-value: 3e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1"
                     /sec_met_domain="AMP-binding (E-value: 4e-115, bitscore:
                     370.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-17, bitscore:
                     50.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.4e-67, bitscore:
                     213.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLAVRLRQKGIRKESMVGVLAERSPEMVVSVLAVLKAGGAYVPL
                     DPEYPEDRLRYMLDDCGACLLLAQPGLSVSGFSGETLEVSLSALTGETETGAVSEEADS
                     ASLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFPLTEEDVIVLKSSFSFDASIWQ
                     LFWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPEETR
                     TRLGRTLTRVFAGGEALSPLTAARFADLLPETMLIHGYGPTEATVDAAFYVCDRKRDSG
                     RTRLPIGKPVPGARLYVLDSGGTIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDP
                     FYPGERMYQTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRRIDGIREAAV
                     TARTEHGETALYAYIEGRESDDVRAELATRLPAYMMPAQFIEMTEWPVTPSGKLDRRAL
                     PAPGGAADRRAYTAPRNVTEMKLCGLWEEVLKNGPVGIRDHFFERGGHSLKATALVSRI
                     AKEFGVQVPLQDIFARPTVEELASVIQDLEESPYEAIQPAQKQDTYPVSSAQKRMYVLQ
                     QLEDGGVGYNMPAVLELTGPLDRGRLEETFRQLVERHESLRTSFETGPDGEPVQRIHDS
                     VPFQLDEAESADAFVRPFCLEEAPLFRAALVKESDEHHLLLTDMHHIISDGVSVNTLIK
                     EFGELYAGRSLAPMRLQYKDYAVWQRSFQEKEGYQKQEAYWLKRLEGELPVLELPADKP
                     RPAVRSFAGGSVSCTLDAETASGLHRIARDHG"
     CDS_motif       complement(195..227)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0008"
                     /evalue="1.60E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg1_1"
                     /protein_end="721"
                     /protein_start="710"
                     /score="17.4"
                     /tool="antismash"
                     /translation="QYKDYAVWQRS"
     CDS_motif       complement(258..323)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0007"
                     /evalue="6.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg1_1"
                     /protein_end="700"
                     /protein_start="678"
                     /score="28.3"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNTLIKEFGELY"
     CDS_motif       complement(498..605)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0006"
                     /evalue="1.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg1_1"
                     /protein_end="620"
                     /protein_start="584"
                     /score="59.3"
                     /tool="antismash"
                     /translation="YNMPAVLELTGPLDRGRLEETFRQLVERHESLRTSF"
     aSDomain        complement(723..926)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1_PCP.1"
                     /evalue="2.30E-25"
                     /label="ctg1_1_PCP.1"
                     /locus_tag="ctg1_1"
                     /protein_end="545"
                     /protein_start="477"
                     /score="80.5"
                     /tool="antismash"
                     /translation="EMKLCGLWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFG
                     VQVPLQDIFARPTVEELASVIQD"
     aSModule        complement(723..2354)
                     /complete
                     /domains="nrpspksdomains_ctg1_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg1_1_PCP.1"
                     /locus_tags="ctg1_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1203..1268)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0005"
                     /evalue="1.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg1_1"
                     /protein_end="385"
                     /protein_start="363"
                     /score="36.7"
                     /tool="antismash"
                     /translation="WLGRSDGQVKVRGYRIEPGEIE"
     aSDomain        complement(1233..2354)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1_AMP-binding.1"
                     /evalue="6.60E-99"
                     /label="ctg1_1_AMP-binding.1"
                     /locus_tag="ctg1_1"
                     /protein_end="375"
                     /protein_start="1"
                     /score="323.1"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="RLAVRLRQKGIRKESMVGVLAERSPEMVVSVLAVLKAGGAYVPLD
                     PEYPEDRLRYMLDDCGACLLLAQPGLSVSGFSGETLEVSLSALTGETETGAVSEEADSA
                     SLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFPLTEEDVIVLKSSFSFDASIWQL
                     FWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPEETRT
                     RLGRTLTRVFAGGEALSPLTAARFADLLPETMLIHGYGPTEATVDAAFYVCDRKRDSGR
                     TRLPIGKPVPGARLYVLDSGGTIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDPF
                     YPGERMYQTGDIARWTEDGLVEWLGRSDGQVKVR"
     CDS_motif       complement(1350..1439)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0004"
                     /evalue="3.00E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_1"
                     /protein_end="336"
                     /protein_start="306"
                     /score="57.8"
                     /tool="antismash"
                     /translation="PAGVAGELYIAGTGVARGYLNRPELTEERF"
     CDS_motif       complement(1425..1466)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0003"
                     /evalue="3.40E+00"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_1"
                     /protein_end="311"
                     /protein_start="297"
                     /score="1.5"
                     /tool="antismash"
                     /translation="VLDSGGTIQPAGVA"
     CDS_motif       complement(1977..2036)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0002"
                     /evalue="3.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_1"
                     /protein_end="127"
                     /protein_start="107"
                     /score="34.6"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGTPKGVAVEH"
     CDS_motif       complement(2220..2261)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1_0001"
                     /evalue="1.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg1_1"
                     /protein_end="46"
                     /protein_start="32"
                     /score="21.2"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLD"
ORIGIN
        1 gagccgtgat cccgggcgat gcggtgaagg ccggatgccg tttcagcgtc aagcgtgcac
       61 gatacgctgc cgcccgcaaa gcttctgaca gccggacggg gcttgtcagc cgggagctca
      121 agcaccggga gctctccttc tagccgcttc agccaatacg cttcctgttt ctggtaccct
      181 tctttctcct gaaacgaccg ctgccagacg gcatagtctt tatattgaag gcgcatcggc
      241 gcaagcgaac ggcctgcgta cagctcgccg aattctttta tcaaggtgtt gacggacaca
      301 ccgtcagaaa taatatgatg catatccgtt aataaaagat ggtgttcgtc ggattctttc
      361 acgagggccg cacggaagag cggcgcttcc tccagacaaa acggccggac gaatgcgtca
      421 gctgactcgg cctcatcgag ctgaaacggt acgctgtcat ggatgcgctg caccggttcg
      481 ccgtcaggcc ccgtttcaaa ggacgttctg agcgactcgt gccgctccac aagctgccgg
      541 aacgtctcct ccagccggcc gcggtcaagc gggcccgtca gttccagcac agccggcata
      601 ttgtagccga caccgccgtc ttcaagctgt tggagcacat acatccgttt ctgcgccgaa
      661 gacaccgggt aggtgtcctg tttttgcgca ggctgaattg cttcatacgg gctctcttcc
      721 aagtcctgaa taaccgaagc gagttcttcc accgtcggcc gggcgaagat gtcttgtaac
      781 ggcacctgaa caccgaactc tttggcaatg cgggagacga gagccgtcgc ttttaacgaa
      841 tggccgcccc gctcaaaaaa gtgatctcgg atgccgacgg ggccgttttt cagcacctct
      901 tcccaaagac cgcaaagctt catttccgtg acgttccgcg gggcggtgta cgcccgtctg
      961 tctgccgctc cgccgggagc cggcagcgcg cggcggtcaa gctttccgct cggcgtgacc
     1021 ggccactcgg tcatctctat aaactgagcc ggcatcatgt aagccggaag gcgtgtcgca
     1081 agctccgccc gcacgtcatc gctttcccgt ccttcgatat aggcgtaaag cgcggtttcg
     1141 ccgtgttcgg tccgggcggt gaccgccgcc tcacgaatgc cgtcgatgcg ccggatcgcc
     1201 gcttcgattt cccccggttc aatccggtag ccgcggactt tcacctgtcc gtctgaacgg
     1261 ccgagccatt cgacaaggcc gtcttctgtc cagcgtgcga tatcgcctgt ctgatacatg
     1321 cgttctcccg gataaaacgg atcatcgaga aaacgctcct ccgtcagctc aggtcggttc
     1381 agatagccgc gggccacccc tgtcccagcg atgtacagct ctcctgccac gcccgcaggc
     1441 tggatggttc ctccgctatc taatacatac agacgggcac ccggaacggg ttttccgatc
     1501 ggaagccttg tccgtccgct gtcccgtttt cggtcacaga cgtaaaacgc cgcatcaacc
     1561 gtcgcttccg tcggtccata gccgtgaata agcatcgtct ccggcaacag atctgcaaac
     1621 cgggcagccg taagcgggga aagagcttcg cctccggcaa acacgcgtgt cagtgttctg
     1681 ccgaggcgtg ttcttgtttc ctcaggctcc gtttccagcg cgtctaaaaa gctgttgacc
     1741 attgccggaa taaaatgcgc ggtcgtcacc ttttctgagg caaacgcttc aatcatccgc
     1801 acaggatctt tctcccagcc ggcaggaagc agatacacgg aggcgcctga catcgtccac
     1861 caaaacaatt gccagataga ggcgtcgaat gaaaaggatg atttcagcac gataacatcc
     1921 tcttccgtta acggaaactg cccttgcatc cctgataaaa aggcggcggc ctgacggtgt
     1981 tcaacagcca ctcccttcgg tgttcccgtc gaaccggacg tataaatgat ataagcgagc
     2041 gaagcgctat ccgcttcttc agagacagcc cctgtctccg tctcgcctgt cagagcagaa
     2101 agagacactt ctagcgtttc tccggaaaaa ccggaaacgg ataatcccgg ctgtgcaagc
     2161 agaagacaag cgccgcagtc atcgagcata tagcgcagcc tgtcctcagg atactccggg
     2221 tcaagcggca cgtaggcgcc gcccgctttt aacacggcaa gcactgaaac caccatctcc
     2281 ggcgagcgtt cagcgagtac gccgaccatg ctttctttgc ggatgccttt ttggcggagc
     2341 cgaacggcga gcctgtc
//
