LOCUS       gnlProkkaMLHCIMPN_5     1945 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MLHCIMPN_5.
ACCESSION   gnlProkkaMLHCIMPN_5
VERSION     gnlProkkaMLHCIMPN_5
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:50:41
            Original ID  :: gnl|Prokka|MLHCIMPN_5
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1945
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1945
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:1945]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..1945
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..1945
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1945
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(2..1945)
                     /NRPS_PKS="Domain: AMP-binding (1-375). E-value: 4e-99.
                     Score: 323.8. Matches aSDomain:
                     nrpspksdomains_ctg5_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (473-541). E-value: 8.9e-26. Score:
                     81.8. Matches aSDomain: nrpspksdomains_ctg5_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     340.6; E-value: 2.1e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-115, bitscore:
                     371.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.4e-18, bitscore:
                     51.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.9e-28, bitscore:
                     83.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLAVRLRQKGIRKESMVGVLAERSPEMVVSVLAVLKAGGAYVPL
                     DPEYPEDRLRYMLDDCGACLLLAQPGLSVSGFSGETLEVSLSALTGETETGAVSEEADS
                     ASLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFPLTEEDVIVLKSSFSFDASIWQ
                     LFWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPEETR
                     TRLGRTLTRVFAGGEALSPLTAARFADLLPETMLIHGYGPTEATVDAAFYVCDRKRDSG
                     RTRLPIGKPVPGARLYVLDSGGTIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDP
                     FYPGERMYQTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRRIDGIREAAV
                     TPRTEHGETALYAYIEGRESDDVRAELATRLPAYMMPAQFIKMSEWPVTPSGKLDRRAL
                     PAPGGAADTAPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEF
                     GVQVPLQDIFARPTVEELASVIQDLEESPYEAIQPAKKQDTYPVSSAQKRMYVLQQLED
                     GGVGYNMPAVLELTGPLDRSRLEETFRQLVERHESLRTSFETGPDGEPVQRIHDSVPFQ
                     LDEAESADAFVRP"
     CDS_motif       complement(98..205)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg5_1_0006"
                     /evalue="9.30E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg5_1"
                     /protein_end="616"
                     /protein_start="580"
                     /score="59.8"
                     /tool="antismash"
                     /translation="YNMPAVLELTGPLDRSRLEETFRQLVERHESLRTSF"
     aSDomain        complement(323..526)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg5_1_PCP.1"
                     /evalue="8.90E-26"
                     /label="ctg5_1_PCP.1"
                     /locus_tag="ctg5_1"
                     /protein_end="541"
                     /protein_start="473"
                     /score="81.8"
                     /tool="antismash"
                     /translation="EMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFG
                     VQVPLQDIFARPTVEELASVIQD"
     aSModule        complement(323..1942)
                     /complete
                     /domains="nrpspksdomains_ctg5_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg5_1_PCP.1"
                     /locus_tags="ctg5_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(791..856)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg5_1_0005"
                     /evalue="8.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg5_1"
                     /protein_end="385"
                     /protein_start="363"
                     /score="37.0"
                     /tool="antismash"
                     /translation="WLGRSDGQVKVRGYRIEPGEIE"
     aSDomain        complement(821..1942)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg5_1_AMP-binding.1"
                     /evalue="4.00E-99"
                     /label="ctg5_1_AMP-binding.1"
                     /locus_tag="ctg5_1"
                     /protein_end="375"
                     /protein_start="1"
                     /score="323.8"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="RLAVRLRQKGIRKESMVGVLAERSPEMVVSVLAVLKAGGAYVPLD
                     PEYPEDRLRYMLDDCGACLLLAQPGLSVSGFSGETLEVSLSALTGETETGAVSEEADSA
                     SLAYIIYTSGSTGTPKGVAVEHRQAAAFLSGMQGQFPLTEEDVIVLKSSFSFDASIWQL
                     FWWTMSGASVYLLPAGWEKDPVRMIEAFASEKVTTAHFIPAMVNSFLDALETEPEETRT
                     RLGRTLTRVFAGGEALSPLTAARFADLLPETMLIHGYGPTEATVDAAFYVCDRKRDSGR
                     TRLPIGKPVPGARLYVLDSGGTIQPAGVAGELYIAGTGVARGYLNRPELTEERFLDDPF
                     YPGERMYQTGDIARWTEDGLVEWLGRSDGQVKVR"
     CDS_motif       complement(938..1027)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg5_1_0004"
                     /evalue="2.40E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg5_1"
                     /protein_end="336"
                     /protein_start="306"
                     /score="58.2"
                     /tool="antismash"
                     /translation="PAGVAGELYIAGTGVARGYLNRPELTEERF"
     CDS_motif       complement(1013..1054)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg5_1_0003"
                     /evalue="2.80E+00"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg5_1"
                     /protein_end="311"
                     /protein_start="297"
                     /score="1.8"
                     /tool="antismash"
                     /translation="VLDSGGTIQPAGVA"
     CDS_motif       complement(1565..1624)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg5_1_0002"
                     /evalue="3.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg5_1"
                     /protein_end="127"
                     /protein_start="107"
                     /score="34.9"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGTPKGVAVEH"
     CDS_motif       complement(1808..1849)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg5_1_0001"
                     /evalue="1.10E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg5_1"
                     /protein_end="46"
                     /protein_start="32"
                     /score="21.5"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLD"
ORIGIN
        1 acggccggac gaatgcgtca gctgactcgg cctcatccag ctgaaacggt acgctgtcat
       61 ggatgcgctg caccggttcg ccgtcaggcc ccgtttcaaa ggacgttctg agcgactcat
      121 gccgctccac aagctgccgg aacgtctcct ccagccggct gcggtcaagc gggcccgtca
      181 gttccagcac agccggcata ttgtagccga caccgccatc ttcaagctgc tggagcacat
      241 acatccgttt ctgcgccgaa gacaccggat aggtgtcctg ttttttcgca ggctgaatcg
      301 cttcatacgg gctctcttcc aagtcctgaa taaccgaagc aagctcttcc accgtcggcc
      361 gggcgaagat gtcctgtaac ggcacctgaa caccgaactc tttggcgatg cgggagacga
      421 gagccgtcgc ttttaacgaa tggccgcccc gctcaaaaaa gtgatcccgg atgccgacgg
      481 ggccgttttt tagcacctct tcccaaagag cgcaaagctt catttccgtg acgttccgcg
      541 gggcggtgtc tgccgctccg ccgggagccg gcagcgcgcg gcggtcaagc tttccgctcg
      601 gcgtgaccgg ccattcgctc atctttatga actgagccgg catcatgtag gccggaaggc
      661 gtgtcgcaag ctctgcccgc acgtcatcgc tttcccgtcc ttcgatatag gcgtaaagcg
      721 cggtttcgcc gtgttcggtc cggggggtga ccgccgcctc acgaatgccg tcgatgcgcc
      781 ggatcgccgc ttcgatttct cccggttcaa tccggtagcc gcggactttc acctgtccgt
      841 ctgaacggcc gagccattca acaaggccgt cttctgtcca gcgtgcgata tcacccgtct
      901 gatacatgcg ttctcccggg taaaacggat catcgagaaa acgctcctct gtcagctcag
      961 gccggttcag atagccccgg gccacgccgg tccccgcgat gtacagctct cctgccacgc
     1021 ccgcaggctg gatggttccc ccgctatcta atacatacag acgggcaccc ggaacgggtt
     1081 ttccgatcgg aagccttgtc cgtccgctgt cccgttttcg gtcacagacg taaaacgccg
     1141 catcaaccgt cgcttccgtc ggtccatagc cgtgaataag catcgtctcc ggcaacagat
     1201 ctgcaaaccg ggcagccgta agcggggaaa gagcttcgcc tccggcaaac acgcgtgtca
     1261 gtgttctgcc gaggcgtgtt cttgtttcct caggctccgt ttccagcgcg tctaaaaagc
     1321 tgttgaccat tgccggaata aaatgcgcgg tcgtcacctt ttctgaggca aacgcttcaa
     1381 tcatccgcac aggatctttc tcccagccgg caggaagcag atacacggag gcgcctgaca
     1441 tcgtccacca aaacaattgc cagatagagg cgtcgaatga aaaggatgat ttcagcacga
     1501 taacatcctc ttccgttaac ggaaactgcc cttgcatccc tgataaaaag gcggcggcct
     1561 gacggtgttc aacagccact cccttcggtg ttcccgtcga accggacgta taaatgatat
     1621 aagcgagcga agcgctatcc gcttcttcag agacagcccc tgtctccgtc tcgcctgtca
     1681 gagcagaaag agacacttct agcgtttctc cggaaaaacc ggaaacggat aatcccggct
     1741 gtgcaagcag aagacaagcg ccgcagtcat cgagcatata gcgcagcctg tcctcaggat
     1801 actccgggtc aagcggcacg taggcgccgc ccgcttttaa cacggcaagc actgaaacca
     1861 ccatctccgg cgagcgttca gcgagtacgc cgaccatgct ttctttgcgg atgccttttt
     1921 ggcggagccg aacggcgagc ctgtc
//
