LOCUS       gnlProkkaPICBCKBE_1    28501 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PICBCKBE_1.
ACCESSION   gnlProkkaPICBCKBE_1
VERSION     gnlProkkaPICBCKBE_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 03:02:23
            Original ID  :: gnl|Prokka|PICBCKBE_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 639209
            Orig. end    :: 667710
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..28501
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:18501]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18501
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..28501
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..28501
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="2"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             1278..2585
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 347.9; E-value: 1e-105)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_595"
                     /transl_table=11
                     /translation="MELRNAVPVKKARKKTKARYIILFVLFLSTALNYLDRTNISVAAP
                     LMKGDLHLNPVALGLVFSAFGWTYAIMQIPGGWLLDKFGPRRLYGVALGVWSAFTFFQA
                     FAKGFTSLFGLRLGLGLSEAPAFPTNNRLVSTWFPKQERAFATGFYTAGEYVGLAFLTP
                     VLAWIVSDFSWQAIFIVTGVLGFLFIPIWFKFVHEPKDSPYVNEEELDYIAKGDGITEN
                     TEEKKKLTWSQISILFKKRTLWGIYIGQFGVTTTLWFFLTWFPTYLVNEKHMTIIHAGF
                     YAMVPYIAAFCGVLFGGALSDWFIRRGFSTSFSRKTPVIIGLLLACTIVLANYTSSIGL
                     VITIMSVAFFAQGMSGISWTLIGDVAPKELMGLAGGIFNFAGNLSGIVTPIVIGMIIGE
                     SQHFGGALIFVSAVALIGALSYLFLIGKVERIEIES"
     CDS             2726..3388
                     /locus_tag="ctg1_596"
                     /transl_table=11
                     /translation="MEKSLEKASLTVEQVKKLFIYTGEKVQENKQLLTKIDGAIGDGDH
                     GIGMSLGFKKANEKLRETEFTTVNEIFKTIGVSMISSMGGASGVIFGTLFTGGLKGLDP
                     QETLDSNLLANILENALNAIKQRGKADLGDKTMIDALEPAVLALKQKAENDAGLLACLK
                     AAEEAAAQGVEKTKSYIAKFGRAKTLGERAIGHQDAGATTVWIIFKSMKEYIENLSV"
     CDS             3451..4368
                     /locus_tag="ctg1_597"
                     /transl_table=11
                     /translation="MVAKFHGIIPPVSIIFDKNGKFDQKGMAVVIDFLIDSGVNGLFFL
                     GSGGEFTQMSTEERMEVASFATEYVNGRVPVLIGTGSTNTRESILLSQHAEKVGADGVV
                     VINPYYWPLTEENLYRHYHDIAQSIEISVLLYNFPTLSGQDLNPEFVLKLVENHQNIVG
                     IKETVEEVSHIRDMISIVKKKHPDFAVFCGFDDHLLQTLTIGGDGAICASVNFAPELAI
                     GIYHAFQEKQYDKAIALHKKLAFLPAIYKLDSPFISVVKEAMKYKGLDISSYVLPPSRP
                     LDEKKKEALKQILSEAGLLEETLQ"
     CDS             4406..4810
                     /locus_tag="ctg1_598"
                     /transl_table=11
                     /translation="MSSLPVPFALRCRRIRIGEKSNDPASIAAGARIGTEQGADIIKMR
                     LTRKPEDIQVIQSAKKPVIALGGPKADDMLEYFMFIQHCIEVGAKGVAIGRNIVQNEDP
                     ADFVAGLNKIIHLNGTAEEAYQVYINHSLT"
     CDS             4900..5919
                     /locus_tag="ctg1_599"
                     /transl_table=11
                     /translation="MKKVINDPANVVEETIEGFLAAYKDQFRKVDDVNGVVRRDHKEKV
                     AVVTGGGSGHEPLFIGLLGEGLADGVTLGNVFAAPNPYNIQEVAKAADKGKGVLFVYGN
                     YSGDILNFDMATELLELEGIECRTVRVTDDVASAPADRKTDRRGIAGDVFVVKIAGAAS
                     ETGLSLEEVTRITQKANDHTFSIGVGLTPGSIPGAAEPPYTLGDDEMEVGLGIHGEPGV
                     KRTKLLPADELTDNLMDTLLKESGITAGDEVCVLVNGLGSTTLMELFIVNRRVTKILEE
                     KGIRAYDIDVNSYCTTQEMGGFSITLLKLDDELKAYYDAPAISPYYKKLEKKPVKATQ"
     CDS             5944..6729
                     /locus_tag="ctg1_600"
                     /transl_table=11
                     /translation="MKRIWIGTNWKMTKTIEEGISYTKELKRISEMISDNIELFIIPPY
                     TSLVTIKGVIRDSRIQLGAQNMHWEDSGAFTGEISPKMLDEIGINLIELGHSERRQYFN
                     EKDEDLNKKVHAALKYHFRPLICIGENRKQKDQGISKEVLASQIKVCLRNVPEEQALNV
                     MIAYEPVWAIGENGVPADAGYVREVHAFLRDTLNQLYPSVGKEIPILYGGSVNKDNFLQ
                     YIDVEHVNGLFIGRAAWDIESFEYILKSLDTHLFKKMTS"
     CDS             6992..7768
                     /locus_tag="ctg1_601"
                     /transl_table=11
                     /translation="MFADQRRKAIQDLLAEKGTVTVNELTGLLNTSAATIRSDLNHMEM
                     QGLLIRTHGGAIKKDSQEPDLGENNYEIREKKFRAEKQRIGKAALKFLQEGQCILLDAS
                     STCFEFARYLKDINMKLTVVTSGISTAVMLKENPHLTVIIVGGIVRNSSNSVEGLLGEE
                     LLRKINIDILFTSAYAFNMNDGLTDFSYYEVELKRKMVAASHKVIALLDHSKIDKSSFA
                     TFAQPEEIDILITDKEVTEEMNRFFNQHGILFEVAK"
     CDS             7937..9454
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 437.7; E-value:
                     9.3e-133)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_602"
                     /transl_table=11
                     /translation="MTIFLFTFFLFRLCRQHVYQLISTRGEDTIKIVTAFKNKSINFSM
                     EKGNGMISEKFLNTRLLDIVFGKTYSGTLIVDHEGYIRYISRNFCDFLKVERNEVIGEH
                     VTHTIENTRMHLVVKTGKAELAQLQFLRGEYVIANRIPIIEDGKILGAVGIIIFRDLYD
                     WQKLNTHIRHMLSQSRFLLEKQPRAAGVKYMLNDLIGSSRQMALLKEKIKKVARGDITV
                     LITGESGTGKELVAHSIHSSSDRSSGPFIKINCGAIPEHLMESELFGYEEGSFTGAKKG
                     GKPGKFQAAEGGTIFLDEIGDMPVMMQVKLLRVLQEKEIEPVGAVHPKPIDVRIIAATN
                     QPLKELVEQNRFRKDLYYRINAIQLDIPPLRTRAEDIPLLARHFLKKASSGLGKRVTGF
                     SPEALSALEGYNWPGNIRELENAVHAAVYMASSDAIGLEDLPEAIREHLNRKKESSLKE
                     RMEAAEKQMIEEALRAACFDKKRAAKALGIGHSTLYDKMKKLRIEVK"
     CDS             10001..11551
                     /NRPS_PKS="Domain: AMP-binding (19-419). E-value: 8.2e-94.
                     Score: 306.3. Matches aSDomain:
                     nrpspksdomains_ctg1_603_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     389.7; E-value: 2.7e-118)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_603"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-106, bitscore:
                     354.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVGWMIKNIAEDPDPLVSGKTAVQEEAGRAWTFKELHAISNAYA
                     NKLTQLGVRKGDRVGILLYNCLEYFGLYFAAAKIGAIAVRLNFRLSSPELVYCLNDSGT
                     KILCFHAGLAGRIEPIQHEVPVEQFICLQEEASVVPGWAQPFSVLGEGQQEDPAVSSIH
                     LNDPVMLMYTSGTTGRPKGAIWTHNTTFWFSAIQALKWGFQARETAMTTGPLYHVGAME
                     DIALPVLMRGGTVIITKSKNFEIQRVLSVMEKEKVTCCFLFPFMIYDMLHLPDLAQYRL
                     ETLKTIYTGGDPLMPWALESIRAHFPHIGVVQVYGLTEGQPIAASLDPQDAAGKGSTVG
                     KPMPLTAIQIADDAGNPLPAGEVGEILIKSPAVSEGYWKKPEATMETFADGWCKTGDLG
                     FFDSEGFLTIAGRKKDMIRSGGENIYPAEIEDVLYRHEAVKEVTVIGIPDPKYMETVCA
                     IIVKKDGARLTEKEVAEFCKRHLASYKKPRKVIFVKEIPRTPSGKVQKFKLREQFGAG"
     aSDomain        10058..11257
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_603_AMP-binding.1"
                     /evalue="8.20E-94"
                     /label="ctg1_603_AMP-binding.1"
                     /locus_tag="ctg1_603"
                     /protein_end="419"
                     /protein_start="19"
                     /score="306.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="GKTAVQEEAGRAWTFKELHAISNAYANKLTQLGVRKGDRVGILLY
                     NCLEYFGLYFAAAKIGAIAVRLNFRLSSPELVYCLNDSGTKILCFHAGLAGRIEPIQHE
                     VPVEQFICLQEEASVVPGWAQPFSVLGEGQQEDPAVSSIHLNDPVMLMYTSGTTGRPKG
                     AIWTHNTTFWFSAIQALKWGFQARETAMTTGPLYHVGAMEDIALPVLMRGGTVIITKSK
                     NFEIQRVLSVMEKEKVTCCFLFPFMIYDMLHLPDLAQYRLETLKTIYTGGDPLMPWALE
                     SIRAHFPHIGVVQVYGLTEGQPIAASLDPQDAAGKGSTVGKPMPLTAIQIADDAGNPLP
                     AGEVGEILIKSPAVSEGYWKKPEATMETFADGWCKTGDLGFFDSEGFLTIAGRKKDMIR
                     S"
     CDS_motif       10505..10561
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_603_0001"
                     /evalue="4.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_603"
                     /protein_end="187"
                     /protein_start="168"
                     /score="22.3"
                     /tool="antismash"
                     /translation="MLMYTSGTTGRPKGAIWTH"
     CDS_motif       11075..11164
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_603_0002"
                     /evalue="4.70E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_603"
                     /protein_end="388"
                     /protein_start="358"
                     /score="28.5"
                     /tool="antismash"
                     /translation="PAGEVGEILIKSPAVSEGYWKKPEATMETF"
     CDS_motif       11228..11290
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_603_0003"
                     /evalue="2.10E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg1_603"
                     /protein_end="430"
                     /protein_start="409"
                     /score="14.1"
                     /tool="antismash"
                     /translation="AGRKKDMIRSGGENIYPAEIE"
     CDS             12211..14166
                     /NRPS_PKS="Domain: AMP-binding (85-522). E-value: 1.3e-86.
                     Score: 282.6. Matches aSDomain:
                     nrpspksdomains_ctg1_604_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     281.3; E-value: 2.1e-85)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_604"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-95, bitscore:
                     316.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQSGIAKSKLVYPSDDKIRSTEIGSSEAFEELLRLSQTDPEAFW
                     GRVAKKLTWYEPWKETMTGSLPGFRFFEGGVSNPCVNLLDRHVENGAGNRTALIWEGEN
                     GDSKFFTYHMLLAEVNRFSNVLRGFGVKKGDCVAIFLPNLAEAVIAVLACFRIGAIYNT
                     IFSGYSEKSLKDRLVNFEPKVIVTADATERRGKKIFLKEKVDRVVPDIPSVKAVVVVDR
                     LGTDVNMQAGRDCWWHEETRKASIHCEPERLEANEYGIVFYTSGTTGKPKGVVHSGMAF
                     VVQNYIYAKYHMDHHDDDVLWCSADIGWLTMHIWGIAGALSNGVTTIFYEGAIDYPEKD
                     RFYQIIEKYRVNKLFTAPTALRMLKSMGERPLEKYDLSCLDVVSLVGEPFDAETWQWTY
                     EVLGRKKICVNNTWGQTETAGSPLAGAAWLTPMKPGSAGRPFLGAVIGVVDQEGNPVPR
                     GTLGNLVIQKPFPMLCRTLWKEPERYLGSYFSQVDGCYYASDLAMIDEDGYVWVTGRSD
                     DAFNVAGHRLSTMEMESAVLETPGVSETAVIGVPDEIKGEVPVCFVRLSDGTEESEELK
                     EAIKARIVDQIGKIAVPKTILFTDTLPKTVSGKIMRRLLKEIVVNGAATGDMTGLEDPA
                     TIARIEQLVASRRAER"
     aSDomain        12466..13776
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_604_AMP-binding.1"
                     /evalue="1.30E-86"
                     /label="ctg1_604_AMP-binding.1"
                     /locus_tag="ctg1_604"
                     /protein_end="522"
                     /protein_start="85"
                     /score="282.6"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="RHVENGAGNRTALIWEGENGDSKFFTYHMLLAEVNRFSNVLRGFG
                     VKKGDCVAIFLPNLAEAVIAVLACFRIGAIYNTIFSGYSEKSLKDRLVNFEPKVIVTAD
                     ATERRGKKIFLKEKVDRVVPDIPSVKAVVVVDRLGTDVNMQAGRDCWWHEETRKASIHC
                     EPERLEANEYGIVFYTSGTTGKPKGVVHSGMAFVVQNYIYAKYHMDHHDDDVLWCSADI
                     GWLTMHIWGIAGALSNGVTTIFYEGAIDYPEKDRFYQIIEKYRVNKLFTAPTALRMLKS
                     MGERPLEKYDLSCLDVVSLVGEPFDAETWQWTYEVLGRKKICVNNTWGQTETAGSPLAG
                     AAWLTPMKPGSAGRPFLGAVIGVVDQEGNPVPRGTLGNLVIQKPFPMLCRTLWKEPERY
                     LGSYFSQVDGCYYASDLAMIDEDGYVWVTGRSDDAFNV"
     CDS_motif       12991..13041
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_604_0001"
                     /evalue="8.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_604"
                     /protein_end="277"
                     /protein_start="260"
                     /score="21.6"
                     /tool="antismash"
                     /translation="VFYTSGTTGKPKGVVHS"
     CDS             14423..15565
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 442.4; E-value:
                     2.3e-134)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_605"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 8e-40, bitscore:
                     133.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1e-27, bitscore:
                     93.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5e-52, bitscore:
                     173.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFELSKEQIMLQEMVRDFAEKEIEPYAREVDETGKMRMETFQKL
                     GNLGLLGIPFPEKYGGAGGDTISYCIAVEEIGKACGGTGLSYAANTSLGASPIYYFGTE
                     EQKQKWLVPMAKGEALGAFGLTEPNAGSDAGGTRTKAVLDGDEWVINGEKCWITNAEYA
                     RQVIVTAVTGKRENGRNIISAIIVPTDAPGVTITSPYEKMGVRGSNTCQIVLENVRVPR
                     ENLLGDEKKGFSQFLYTLDGGRISIAALSVGIAQAAFEKALRYAKERMQFGQAISKFQA
                     IQFKLADMAMEIDLARNAVYKAAWLKDQGKPFSKEAAYAKLFASEMGFRVCNQAIQIHG
                     GSGYMREYDVERHLRDIKLMEIGEGTSEIQRLVIARKLGC"
     CDS             15787..17142
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     649.7; E-value: 9.5e-197)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_606"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.9e-11,
                     bitscore: 41.5, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4.3e-07, bitscore:
                     27.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKILIANRGEIARRVIRTCKKLGIKSVAVYSEADAGALFVREA
                     DEAYCIGKSPVNQSYLNADAIIRAAKESGAEAVHPGYGLLSENAPFARKCIEAGLIFIG
                     PSPAIIAAMGSKIEARRTMKAAGVPVIEGVDDPLEDEEAAVRAAEKIGYPAMLKASAGG
                     GGIGMQVVQTEKELRKAFAGNKKRAEMFFGDGAMFIEKYIEEPHHVEIQILADQYGNVV
                     PLMERECSIQRRHQKVVEEAPSPFISEATRQKMLDAAVKAATSIGYINAGTMEMIVDRG
                     QNFYFLEMNTRLQVEHPVTEEITGLDIVEEQLKIASGERLTITRETLKRNGHAIEVRIY
                     AEDPKTFLPSPGKITAFRLPEGEGIRNETAVEAGSEVTPFYDPMIAKLIAWGSSREEAC
                     KRIRNALLNYQVEGIKTNIPMLIDTVRHEQFLKGYTTTHFVNDFLKQAESRK"
     CDS             17357..17566
                     /locus_tag="ctg1_607"
                     /transl_table=11
                     /translation="MEITASMAGSVWKVLVKEGDQVKEGDDVVVLESMKMEIPIAAEED
                     GTVVKIHVQEGEFVNESDVLVELE"
     CDS             17593..18501
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 229.4;
                     E-value: 1.5e-69)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_608"
                     /sec_met_domain="HMGL-like (E-value: 1.1e-46, bitscore:
                     157.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPEKVTVKEVGPRDGLQNEKAVVATAEKVAWVNALSDTGLTYI
                     EAGSFVRPEWIPQLADTGAVLEKIRRKPGVTYAALVPNVRGLERALNAGVDEVSVFMSA
                     SEGHNLRNINKTIAETYPVLEKVVKEAKNAGKSVRGYISTVIACPYDGPVSPKQVKEVA
                     GRLFAMGVDEISLGDTIGAGVPTDVERLLGELLKDFHARQLAMHFHDTRGTALANVVKS
                     LEMGITVFDSAAGGLGGCPYAKGAAGNVATEDLLYLFAQMGIETGVDLGRIIQAAQQIE
                     KTIGRPLASHQMEIYRMAGGA"
     CDS             18632..19411
                     /NRPS_PKS="Domain: ECH (7-251). E-value: 5e-72. Score:
                     234.0. Matches aSDomain: nrpspksdomains_ctg1_609_ECH.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 263.3; E-value:
                     2.9e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_609"
                     /transl_table=11
                     /translation="MTGTVLLEKQDGITVMTLNRPEAANALSKEMLSDMHEALSEVKKD
                     QSTRVVILTGAGEKVFCAGADLKERKGMNEEEVLQAVRKIGAVVNETAALPQPVIAALN
                     GSAFGGGLELALACDLRIGAREAKYGLTETSLAIIPGAGGTQRLPRLIGVGKAKELIYT
                     ARRLTAEEAAAIGLLEYAVPRAAVIEKAFELAGEMQKNGPIALRQAKTAIDQGTETGLS
                     AGLKIEELAYNALIPTEDRLEGLRAFAEKRTPVYKGR"
     aSDomain        18653..19384
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_609_ECH.1"
                     /evalue="5.00E-72"
                     /label="ctg1_609_ECH.1"
                     /locus_tag="ctg1_609"
                     /protein_end="251"
                     /protein_start="7"
                     /score="234.0"
                     /tool="antismash"
                     /translation="EKQDGITVMTLNRPEAANALSKEMLSDMHEALSEVKKDQSTRVVI
                     LTGAGEKVFCAGADLKERKGMNEEEVLQAVRKIGAVVNETAALPQPVIAALNGSAFGGG
                     LELALACDLRIGAREAKYGLTETSLAIIPGAGGTQRLPRLIGVGKAKELIYTARRLTAE
                     EAAAIGLLEYAVPRAAVIEKAFELAGEMQKNGPIALRQAKTAIDQGTETGLSAGLKIEE
                     LAYNALIPTEDRLEGLRAFAEK"
     CDS             19416..20933
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 510.3; E-value: 1.1e-154)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_610"
                     /transl_table=11
                     /translation="MDYESKKAEILKGGKEKYHQKNREQGKWFVRERLRMLLDDGLKAE
                     DGMFANVLAGDLPADGVVTGLGKIGGRTVCVMANDSTVKAGSWGWRTVEKIIRIQETAA
                     KLNCPILYLVDSAGARITDQIEMFPGRRGAGRIFYNEVHLSGKVPQICLLFGPSAAGGA
                     YIPAFCDIVVMVEGNASMYLGSPRMAEMVIGEKVTLEQMGGAKMHCTVSGCGDVLVKTE
                     EEAIRYVQKYLTYFPDNFSEKPARTEAKAPAAFEKTIEELIPKNENAPFDMYQLIERIV
                     DEDSICEIKKKFAPELITCLARIGGRPVGIIANQPRVKGGVLFHDSADKAAKFIHLCDA
                     FHIPLLFLADVPGFMIGTQVERAGIIRHGAKMIFAMSEATVPKLSVIVRKAYGAGLYAM
                     AGPAFEPDCCIALPSASIAVMGPEAAVNAVYANKIAALPEEERPAFFAEKRAEYVKDID
                     IYRLASELVVDDVVPGNELREELERRLEMYSGKQEEFSKPKHPVYPV"
     CDS             21081..21527
                     /locus_tag="ctg1_611"
                     /transl_table=11
                     /translation="MEFRKANLDDLHHLIELRKQQQVAQGIEPKTDIDADLEKFFQKKL
                     KEGSMVQWLAEDEGEIVACGAVIFYEFPPSYVNKSGKKAYITNVYTKEEYRGQGIAKEL
                     MEKLMDEVKKAGISNIWLGASEMGKPLYEKFGFQEVDEWMELHL"
     CDS             21630..21731
                     /locus_tag="ctg1_612"
                     /transl_table=11
                     /translation="MSDFVHDTNSNVYSDGSHEYLKVNSFILKISFS"
     CDS             21917..22087
                     /locus_tag="ctg1_613"
                     /transl_table=11
                     /translation="MIGDYNLSYETLGKYANVPCDVLKAFCEGNDHIDIDHLMNICVNL
                     LMLSFVLRPEL"
     CDS             22258..22821
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_614"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-11, bitscore:
                     41.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYEIAIIGAGPAGASAAIFTAKAGKSTVLFDGGTSATKRALLKNH
                     YGVTEITGPDLVETGKKQAAQFGAELVDEKVESIEKTENGFTIKTEQGSYESKYVILAT
                     GMIASLGEALGVKAKPATEPRVKTVFAVDAQGKTNVPNVWACGTVAGVSMHTIITAGDG
                     AKVAVNLISEIDGKRWVDHDVLGK"
     CDS             23143..23373
                     /locus_tag="ctg1_615"
                     /transl_table=11
                     /translation="MYRIFQCGFVMAFTGLCMMFLVHLVDGYSTVELGNSLISQILLIP
                     RFFLIFGILLLILSFIIWFRNWAKSKAKKIS"
     CDS             23644..23829
                     /locus_tag="ctg1_616"
                     /transl_table=11
                     /translation="MAKKSMIVKQKREPKFKVQAYTRCERCGRPHSVYRKFKLCRICFR
                     ELAYKGEIPGVKKSSW"
     CDS             24344..26515
                     /locus_tag="ctg1_617"
                     /transl_table=11
                     /translation="MNTNQDFFTRKKEESGIVVNAVQQEAVKQTEGPLLLLASPGSGKT
                     TTVIMRIGYLIEEKGVAPARIKAITFSRAAAADMKDRFQKLFPNLPPVDFSTIHSLAFE
                     LVRVFFRRTNVPFLLIEGEAGPYHKKKILRDVYKAINGERITEDQLEELQTYISYIKNK
                     MIPPAKWGKIATGVPEAARILKEYEAFKKQGTGQLLLDFDDMLTHANEIFRRDPNLLCM
                     YQGRYDYVLTDESQDTSMVQHAIVEKLVRRHRNLCVVADDDQSIYSWRGAEPSYLLNFK
                     KVYPDAKILFMEQNYRSSQEVVTAANLFIKRNKHRYDKNMFTENPPAGPIRFVRLPDYK
                     YQAKYLAQNIAASENFSEIAVLYRNNMSSIALINEFDREGIPFYIKDTDNRFFSHWVVQ
                     DILNVMRLTFTDKRADILAQVHSKLDGYITKQQMEAVKGIHNNQSVFDNLIQYAHLKDY
                     QVQKVREVKETLREMRGMPPLDAIHVIRGRLGYEKALENMCKRLGFRKDPLIGILNTLE
                     EIADTLSTMEEFAARLQHLAHILKTAKGNKGRHAVTLSTFHSSKGLEFEKVYMIDLVDG
                     IIPGNDEKEDDLLMEESVRLFYVAMTRAKKSLEMVSYEKRNGSRAMDSPFVAAVKGIVN
                     SVEKAGKTKPEIEVARIGKKTVSIPQNPNAIKDASAFVAGKKIQHRVFGHGEIVDIDGD
                     TLAIRFEKRTIKLSALTCIEKGLLEEADL"
     CDS             complement(26765..28060)
                     /locus_tag="ctg1_618"
                     /transl_table=11
                     /translation="MKTLISSLQWMAFMIAGSIAAPIAIADAFHFSAGETALFVQRTLF
                     VLGIGGLLQGIFGHRMPINEGPAGLWWSVFAIYAGLVGSLYSSSTESLQYLAGALIVTG
                     IFFFLLAFTGFVDQLNKLFTPVVTFIYLLLLVLQLSGSFMKGMLGITGAHQEVRPLVAV
                     LSLVTVLLTFYFGHVKKPWVKQYSIMLGLICGWILFALFGEAPAITFGESWFSLPAVFD
                     FGKPRFDSGAVTTGVFIGLLLTANMITSVRVMGNVTGVRQERVRSSLFISGINQLLAGI
                     FSAVGAVPIAAAAGYVAQTGIKVLKPFLYGACFVSIIALLPPLVHIMSAIPAPVGYAVT
                     FVVFTQLVGLALNDLEKSPDKEIAHTTAGISFLVGIGAMFLPAHATEHLPMMIATFLNN
                     GLILGSVVGILTEQLLIWRKKRNTQENSIREQ"
ORIGIN
        1 aaattcaaca acaaaattta tcgtttattt cccgtttacc tgatacattc ggtttaagca
       61 cagaactaaa gaaagaggca tggttgctca acaactggga aagggtaggc tcacttagca
      121 ataaaaaaga cgcagctatt taccaaattc aagcttttga aagacaaatt caaaaccttc
      181 cttaccggtt tcttgttgtc cactcaaaca atttagatca acgaaaagag aaaaccctaa
      241 atcgggcgat cgaaaaggaa gaaatacaat taaaaaaaga gatagaaaaa ctgagtaaag
      301 ttatctttca ttgtaaagag gacgcactag aagcaattca atcttttaag aaaaaacaaa
      361 aggcttcata tttctgttat aaactaaacg tccagatgag tgatcaacct atcaaacgaa
      421 aaaagagagg aagacctaaa aaggacgaac agacaaaaca agaacaaatc tatcaaatac
      481 aactggaatc gtttgaaaaa gatcatgatt ttatcgaaaa taagaaaaaa atgctcagca
      541 cttttgtttt aatcacaaat aaattagacg aggagacact atccaatcaa gaagttttga
      601 gggtttataa aggacagtcg gccgctgaga cccgtttccg attaatcaaa gattcacaaa
      661 tgattgatgc catttacttg aaaaccccag aaagggttga ggccttaggt attgtgtatg
      721 tgatggcttt attaatctat ggaattttag aatatcgagt tagaaaagaa ctgaaagaaa
      781 agaacctatc tctaatcttg aaaggaaaaa ggaaactcta tcaacccaca ggccaagcat
      841 tgttagagca attagaagat attaccgtga tccttataaa tcaaaatcaa caaaaaataa
      901 ggctcttacc cgataatatt gattcacaag ccaaaaaaat cattgaatta tgcgggtatg
      961 atgtatcaat atacgtgtca aaaaatgtcg aaaacaaagg cgaataacac acaataggag
     1021 gaattcatga aaagaatgtc gaattgaaaa gaattttatc gaaaattcct caaaaataag
     1081 aagatatcat cccaccaagc catttaaata tagttcattc aaaaattaga atgaactata
     1141 tttaagacgt gcgaaatgtg ggtttcaaca cccttgtatc caaatttttg ccaaagctag
     1201 gaattttggt tattcagcaa gctctatgtt aaggaagcat ggaaaaaaga cgttgtttct
     1261 ttacatagag gctgcctatg gaacttagaa atgcagtgcc tgtcaaaaaa gcaaggaaga
     1321 agacgaaggc aaggtatatt atattattcg ttttattttt aagtactgca ctaaactacc
     1381 tcgatagaac taatatttct gttgcagcac cactaatgaa aggtgatctt cacttaaatc
     1441 ctgtagcttt agggttggtt ttttccgctt ttggatggac ttatgccata atgcaaatac
     1501 ctgggggttg gttattagat aagtttggcc cccgccgttt atatggagtt gcattgggtg
     1561 tttggtctgc atttactttc ttccaggctt ttgcaaaagg atttacctca ctttttggtt
     1621 taagactggg actggggctt tctgaagcac ctgcatttcc tacaaacaac cgattggttt
     1681 ccacctggtt tccaaaacaa gagcgggcct ttgctacagg tttctataca gctggagaat
     1741 atgttgggct agctttttta acaccggtcc ttgcttggat tgtttctgat tttagctggc
     1801 aggccatttt tattgtcaca ggggtacttg gtttcctatt tattccaatt tggtttaaat
     1861 ttgtacatga gcctaaagac agtccttatg taaacgaaga agaactcgat tatatcgcta
     1921 aaggtgacgg cattacagag aatacggaag aaaagaaaaa attaacgtgg tcacaaataa
     1981 gcatactttt taagaaacga acactttggg gaatttatat tggccaattt ggagtaacaa
     2041 caacgttatg gttcttttta acttggtttc ctacttatct agtaaatgaa aaacatatga
     2101 caattataca tgctggcttt tatgcaatgg ttccgtatat tgctgctttt tgtggtgtgt
     2161 tatttggtgg agcgctttcc gattggttca tccgccgtgg tttttctacc agttttagca
     2221 ggaaaacgcc agttattatt ggtctcctcc tagcatgtac aattgtattg gcaaactata
     2281 catcatccat tggtctagtt attacaatta tgtctgtggc tttttttgca caaggaatgt
     2341 cggggatttc atggacacta attggggacg ttgcaccaaa ggaactaatg ggactagctg
     2401 gtggaatatt taattttgca ggaaaccttt caggcattgt tacacctatt gtaattggta
     2461 tgattattgg tgaaagtcaa cattttggag gagctctcat ttttgtcagt gctgttgcat
     2521 tgatcggagc actatcatat ttattcttga taggtaaagt tgaaagaatt gagatagaat
     2581 cttaaaattt aattttcaac cttattcttc atttttacag tgaagttaca gttttacatg
     2641 ttaacatggg tattcacgga aaaccaagtg atccgcaacg gcttgaaatg ttgataaatc
     2701 aacatttata gagggaggaa tcagagtgga aaagagttta gaaaaagcca gtttaacagt
     2761 ggaacaagta aagaaacttt tcatttatac aggagaaaaa gtccaggaaa acaagcaact
     2821 actcacgaaa attgatggcg ctattggaga cggggatcac ggaattggca tgtctctagg
     2881 ttttaagaaa gcaaatgaaa aattaaggga aacagaattt acaaccgtta atgaaatatt
     2941 taaaacaata ggagtgtcca tgatctcctc tatgggcggc gcatccggcg tcattttcgg
     3001 aacgttgttt acaggcgggc tgaaaggtct tgaccctcaa gaaacattgg attcgaattt
     3061 attggcaaat attctggaga atgcattaaa cgctattaaa caacgcggaa aggcggactt
     3121 gggagataag acaatgatcg atgcccttga accagcagtt cttgctttaa aacaaaaagc
     3181 tgaaaatgat gctggtttgc ttgcctgtct gaaagcagca gaggaagcag ctgcccaagg
     3241 cgtagaaaaa acgaaatctt atatagcaaa atttggaagg gcaaagacgc tcggagaaag
     3301 agccattggc catcaggatg caggagctac aacggtatgg atcattttta aatcaatgaa
     3361 agaatacatt gaaaatttat ctgtataacc ccgaatataa ttttggtatt tcataagtag
     3421 caaaagcaaa agaagagagg aggaaaagat atggttgcaa aatttcatgg tattattccg
     3481 cccgtctcaa ttatttttga taaaaacggc aagtttgatc aaaaaggaat ggcagttgta
     3541 attgactttt taattgattc cggcgtgaac gggctttttt tccttggaag cggtggggaa
     3601 tttacacaga tgtcgacgga agagcgaatg gaagttgcat catttgcaac ggagtatgta
     3661 aatggtagag tgccggtact gattggtaca ggaagtacga acacgcgcga atccatttta
     3721 ttgagccagc atgcggaaaa agtcggtgct gatggagttg tcgtgattaa cccttactat
     3781 tggcctttaa ccgaagagaa tttatatcgg cattatcatg atattgcaca atccattgaa
     3841 atctctgtat tgctctacaa ttttccaaca ctatccggcc aggatttaaa tccggaattt
     3901 gtactgaaac tggtggaaaa ccatcaaaat attgtcggaa taaaagaaac ggtggaagag
     3961 gtttcccata ttcgggatat gatttcaatc gttaaaaaga aacatccgga ctttgcggtc
     4021 ttttgcggtt tcgatgatca cctgctacag acgcttacaa ttggcggaga cggagcgatt
     4081 tgtgcaagtg tcaattttgc gcctgagttg gcaattggga tttaccatgc ctttcaggaa
     4141 aagcaatatg acaaagccat tgcattgcat aaaaaactgg catttttgcc ggcgatatac
     4201 aaacttgatt ccccgtttat cagtgttgta aaagaagcaa tgaaatataa aggattagat
     4261 atttccagct atgttcttcc gccttcccgc ccgcttgatg agaagaaaaa agaggcgttg
     4321 aaacagattt tatcggaagc tggtttatta gaagaaacac ttcaataaca aaaatgcggc
     4381 acaggaaaaa tcgcttcagg ccgggatgtc cagccttcct gtgccctttg ctttgcgatg
     4441 tagaagaatc cggataggcg aaaaatcaaa tgatcctgct tccattgcag ctggcgcccg
     4501 tatcggtacg gaacagggag cagatattat taaaatgaga ttaaccagaa aaccggaaga
     4561 tatacaggtg attcaatcag ctaaaaagcc ggtaatcgca cttgggggtc caaaagcaga
     4621 cgatatgctg gagtatttta tgttcatcca acattgtata gaggttgggg ctaaaggtgt
     4681 tgcgattgga agaaatattg ttcaaaacga ggatccggct gacttcgttg cggggctaaa
     4741 caaaatcatc catctcaatg gaacagcaga ggaagcctat caagtttata tcaatcactc
     4801 tctgacttga caattttgac aaaaggtaaa caaatcctta taatcagaat aaaagaaaat
     4861 gaaataaaat gataataaaa gaaaatcgga ggcgtttata tgaaaaaagt aatcaacgat
     4921 cctgccaatg ttgttgaaga aacaatcgaa gggttccttg cagcatataa agatcaattc
     4981 cgaaaagttg atgatgtcaa tggtgttgta cggagggatc acaaggaaaa ggtagccgtt
     5041 gttactggag ggggaagcgg acatgaacca ttatttatcg gtttacttgg agaaggtctt
     5101 gctgacggcg taacattggg aaatgtgttt gctgctccga atccatataa cattcaggaa
     5161 gttgcaaaag ctgcagataa aggcaaaggc gttctttttg tatacggcaa ttactccgga
     5221 gatatcttga acttcgatat ggcaactgaa cttttggaat tggaagggat tgaatgccgg
     5281 acagtacggg ttacagatga tgtggcttcc gctcctgcag atagaaaaac ggatcgccgg
     5341 ggcattgcgg gtgacgtttt tgtggtaaaa attgccggcg ccgcttcaga aacaggttta
     5401 tctttggaag aagtaaccag gattacacaa aaagcaaatg accacacctt ttcaattggt
     5461 gtaggattga cgccgggatc cattccgggt gcagctgaac cgccatatac actcggagat
     5521 gacgaaatgg aagtgggtct tgggattcat ggagaaccag gcgtaaaaag aaccaaattg
     5581 ctgcctgctg atgaactgac ggacaactta atggatacac tgttgaaaga aagcggtatc
     5641 actgcaggag atgaagtttg tgtattggta aacggtttgg gttccaccac attaatggaa
     5701 ttattcattg tcaatcggag agtcaccaaa atccttgagg aaaaagggat tcgagcatat
     5761 gacatcgatg taaacagcta ctgtacaaca caggaaatgg gtggattttc cataactttg
     5821 ttgaaattag atgatgagtt aaaggcatat tacgatgcac cggctatctc accttattat
     5881 aaaaaattgg agaaaaaacc tgtaaaagcg acccaataat cagtgagcct ggggggacgg
     5941 aatttgaaaa gaatttggat tggtaccaat tggaaaatga caaagacaat agaagaaggc
     6001 atctcttata caaaagagct gaaacgtatc tctgaaatga tttctgacaa tattgagtta
     6061 tttattatcc ctccttacac gtctttggtt acaataaaag gcgtgataag ggattcccgc
     6121 atacaattgg gcgctcaaaa tatgcattgg gaagacagtg gtgcatttac cggtgaaatt
     6181 tccccgaaaa tgctggatga aatcggcatt aatctgattg agctgggaca ttctgaacgc
     6241 agacaatatt ttaatgaaaa agatgaggat ttaaacaaaa aagtacatgc cgcattaaaa
     6301 tatcattttc ggccgttaat ctgtatcgga gaaaatcgga aacaaaaaga tcagggtatc
     6361 tccaaagaag tgctggcctc acaaataaaa gtttgcttgc gaaacgttcc ggaagaacag
     6421 gcattaaatg taatgattgc atatgaaccg gtttgggcaa taggagagaa tggagtacca
     6481 gcggatgctg ggtatgttag agaagtgcat gcttttctga gagatacgtt aaatcaactt
     6541 tatccttctg taggaaaaga aattccaatt ttgtacggag gaagcgtcaa caaagataat
     6601 tttcttcaat atattgatgt agagcatgta aatggattat ttattggcag ggcagcttgg
     6661 gatatagaaa gtttcgagta catcctaaaa tctcttgata cacatttatt taaaaaaatg
     6721 acaagctgaa aatagaggat cgttatcatt ctttatgtac acccggtaaa taatcccatc
     6781 tgtaaacaga tgggattatt ccactttaca agaaaaagtg cagataaagc atatagcgaa
     6841 aatgagaaat ttcccttttt tatcgatttt tatcggttcc tatgataaag tctaataaga
     6901 aaaataaata aaagcatgta aaacaccccg atttatatat ctatattgtc tcaactttta
     6961 tgtcactgaa gctagaggag aggatgcctt tatgtttgct gatcaacgta gaaaagctat
     7021 tcaagattta ttagcggaga aaggaacagt aactgttaat gagttgacag ggttattaaa
     7081 cacctctgca gcaaccatcc gttctgacct taaccatatg gagatgcaag gcctgttgat
     7141 ccgtacgcat ggcggggcaa taaaaaaaga cagccaggaa cctgacttgg gtgaaaataa
     7201 ttatgagatt cgcgaaaaaa aattccgtgc agaaaaacaa agaattggaa aagctgcgct
     7261 caaatttttg caagaaggcc aatgtattct tcttgacgca agttccactt gttttgagtt
     7321 tgcccgttat ttaaaagata tcaacatgaa actaacggtc gttacaagcg gtatctcgac
     7381 tgctgtcatg ttaaaagaaa acccccactt aaccgttatt attgttggtg gaattgtgag
     7441 aaattcctct aactccgttg aaggactatt gggtgaagaa ctattgcgca agattaatat
     7501 cgacattttg tttacgtctg cctatgcttt taatatgaat gacggactaa cagattttag
     7561 ctattatgaa gtggaattga aaaggaagat ggttgcagca tcacataagg tcattgcact
     7621 gctcgatcac agtaaaatag acaagagttc ttttgctaca tttgctcagc cggaggaaat
     7681 cgatatattg attactgaca aagaagtaac tgaagaaatg aaccgctttt ttaatcagca
     7741 cggcatatta tttgaagttg caaaataatc ccatgtatac tgcatcccat atttatttca
     7801 gtatttttat ttaccactac aggcatggaa gtaaaaatgc tccttttaca tatggcccgg
     7861 aagccactgt ggatatgtcg tgttgtgatg acgctttttg gatggcatta ggaaagtgga
     7921 aggaggggat aatgaattga ctattttctt atttaccttt ttcctcttcc gtttgtgccg
     7981 gcagcatgtt tatcagttga tctcaactcg tggggaagat acaattaaaa ttgtaaccgc
     8041 tttcaaaaat aagtccataa acttcagcat ggaaaagggg aatggcatga tcagcgaaaa
     8101 gtttctcaat accaggttgt tggacatcgt gtttggaaaa acatactccg gcacattgat
     8161 cgtggatcac gaaggatata ttcgttacat aagccgcaat ttttgcgatt ttttgaaagt
     8221 ggaacgaaac gaagtgattg gcgaacacgt gacccataca attgaaaata caagaatgca
     8281 tcttgtggtg aaaacgggaa aagccgaact tgcccagctg cagtttttaa gaggcgaata
     8341 tgtcatcgca aaccgcattc cgatcataga agatggaaaa attctcgggg ctgtcgggat
     8401 tatcattttc agagatctat atgattggca aaagctgaac acccatatcc ggcatatgct
     8461 gtcgcaaagc cggtttttac ttgagaagca gccccgtgca gccggcgtaa aatatatgct
     8521 caacgatctg attggtagtt ctcggcaaat ggcgctcctg aaagaaaaaa tcaaaaaggt
     8581 ggcgcgcgga gatatcaccg ttttgattac cggagagagc ggaaccggaa aggagctggt
     8641 tgctcatagc attcacagct ctagcgaccg gagcagtggt ccgtttatca aaatcaactg
     8701 cggcgcgatt cccgaacatc tcatggaatc cgagctgttc ggatatgaag aaggatcgtt
     8761 caccggtgcg aaaaaaggcg gcaagcccgg caagttccag gcggcggaag gggggacgat
     8821 ttttctcgat gagatcggcg acatgccagt gatgatgcag gtaaaactat tgcgcgtgct
     8881 gcaggaaaaa gaaatcgaac cggttggcgc ggtccatcca aaaccgatcg atgtccgtat
     8941 catcgcggca acaaaccaac cgcttaaaga actggtcgaa caaaaccgtt tcagaaaaga
     9001 cttgtactat cgcatcaatg ccatccagct ggatatccct ccgctccgca ccagggcgga
     9061 agatatccca cttttggcgc ggcatttcct aaagaaagca tcatccggtc tcggcaaaag
     9121 ggtcaccggt ttcagccctg aagccctctc cgcgctcgaa gggtacaatt ggccgggaaa
     9181 catccgcgaa ctggaaaatg ctgttcacgc agcggtctac atggcctctt cggatgcgat
     9241 cgggttagag gacctgcctg aagcaatccg tgaacactta aacagaaaaa aagaaagcag
     9301 tttgaaagaa agaatggagg cagcggaaaa acaaatgatt gaggaagcgc tgcgggctgc
     9361 ctgttttgat aaaaaacgtg cggcaaaagc cctcgggatt ggccactcca cgctttacga
     9421 caaaatgaaa aagcttcgta ttgaggtaaa atgaacgcag tttttcacgt caaacgatca
     9481 ggatagatat tgcttctata tagggcttgc tgaataagcg aaattcctgg atttggaaag
     9541 gatgctgaca gctttggcaa ccatttaaac aaatccaggg aaatgcttgc actcgaaagc
     9601 cgattcaatg tatggagaag atcaaatccc cccttttcgc aaaagaattc ttctatattt
     9661 tgagacagag cttgcagata aattgggcac aaactcagaa tcggattcgt tcagcaagcc
     9721 ctatgtaaaa tgaacttaag ttttgacatc aagcccaaac atccacttgc atgagcacta
     9781 ttttttaatc atccggaaat ccagattggc cttctgaaat tccgaatctg tttttctgcc
     9841 ataaagccgc tgtttgcatc atagattggt aaagaacgtt acggaaaacg ggaaacgaag
     9901 ccgccttttc caacacgcac atgctgtttt tcgcctcttt caagctggca tacttcttgc
     9961 tttttatagg gcatcaaagt gttggaaagg gggaacatgg ttgcacgttg gctggatgat
    10021 caagaacatt gcagaggatc cggacccgct tgtttccgga aaaactgcgg tgcaggaaga
    10081 agccggaaga gcatggactt tcaaggaatt gcacgcgatt tccaatgctt atgcaaacaa
    10141 gcttacacag cttggcgttc ggaaaggaga ccgggtcggc attctgctct ataactgcct
    10201 tgagtatttc ggcctttatt ttgcggcggc gaaaatcggg gcaattgcag tccgtttgaa
    10261 tttccgcttg tcaagccccg aactggtcta ttgcttaaac gactccggca caaaaatatt
    10321 atgttttcac gcaggtcttg ccgggcggat tgagccgatt caacacgagg tgccagttga
    10381 acaatttatc tgccttcagg aggaagcatc agtcgttccg ggatgggcgc aaccgttttc
    10441 cgtgctcggg gaagggcagc aggaagaccc cgctgtgtca tccatccact taaatgaccc
    10501 ggtgatgctg atgtatacgt ccgggacgac gggaaggcca aaaggtgcga tttggacgca
    10561 taatacgaca ttctggtttt cagccattca agctttgaaa tggggatttc aagcccggga
    10621 aacggccatg acaacggggc cgctctacca tgtcggcgca atggaagaca ttgctttgcc
    10681 ggttctcatg cggggcggaa ctgtcatcat tacaaaaagt aaaaacttcg agattcaaag
    10741 agtcctgtct gtcatggaaa aggaaaaggt aacatgctgt tttttatttc cttttatgat
    10801 ttatgacatg ctgcacttac cggatctggc acagtaccgg ctggaaacgc tgaagacgat
    10861 ttacaccggc ggggatccgc tcatgccgtg ggctttggaa agcatccggg cgcattttcc
    10921 gcacattggc gtcgtccagg tgtacggttt gacagaaggg cagccgattg ccgcttcact
    10981 cgacccgcag gatgccgcag gaaaaggcag tacagtcgga aaaccgatgc ctttgactgc
    11041 gattcaaatt gcagatgatg ccggaaaccc gcttcctgca ggagaagtgg gcgaaattct
    11101 cattaagagc cctgctgttt cagaagggta ttggaaaaaa ccggaggcga ccatggagac
    11161 gtttgcggat ggctggtgca aaacagggga tcttggcttt tttgattcgg aagggttttt
    11221 aaccattgcc ggcaggaaga aagatatgat ccggagcggc ggagaaaata tttatcctgc
    11281 tgaaatagaa gatgtgcttt accgccacga agcggtaaaa gaagtcactg tgatcggtat
    11341 ccccgatccg aagtacatgg aaacggtttg cgccattatt gtaaaaaaag atggcgcgcg
    11401 gctgacagaa aaagaagtgg ccgaattttg caaacgccat cttgcaagct ataaaaaacc
    11461 gcgcaaggtc attttcgtga aagaaattcc gcgcacgcct tccggaaaag tgcagaagtt
    11521 caaacttcgc gaacagtttg gcgcgggatg aagaagagga atattttccc actgctataa
    11581 accgtttgca gagaccgggg gagaaaatac caaccttttg attgcccgga taaaaacgcc
    11641 cgggaattca ccacggaatg acaggtcgcg cccgtcagtc tggcagaaaa agcggccata
    11701 caaacgccgt tataaggttg gtgcaacgtc aggcgtttgt atccccaaaa acacggataa
    11761 aaacgcccgg gaattcacca cgggattgac aggtcgcgcc cgtcagtctg gcagaaaaag
    11821 tggccataca aacgccgtta taaggttggt gcaacgtcag gcgtttgtat ccccaaaaac
    11881 acggataaaa acgcccggga attcaccacg gaatgacagg tcgtgcccgt aagtctggca
    11941 aaaaaacagt caaccaacgc tgttctcagg ttggtgcagc atcaggcgtt tgtatcccaa
    12001 aagcacggat aaaaacgccc gggaattcaa tgttggataa aagaaggtgt tcgccactgt
    12061 gccgggaaga gtcgcattca aacgctgtaa atcttttagt ggacagaata ggagaatggc
    12121 tttgataaaa gcgagtgaat cgcgtatgca ggaattttct taaaaaggga acttcgtttt
    12181 cccgaccgat caccggaaag gagcatgtcc atggaacaaa gcggcattgc caaaagcaaa
    12241 ctcgtttatc caagtgatga taaaatccgt tcaaccgaaa tcggttcaag cgaagcattt
    12301 gaggaactgc tgcgcctgtc gcaaacggat ccggaagcat tttgggggcg cgttgccaaa
    12361 aagctcacct ggtatgaacc gtggaaggaa acaatgacag gcagcctccc cgggttccgc
    12421 ttttttgaag gcggtgtgag caacccatgt gtgaacctgc ttgaccgcca tgtcgaaaac
    12481 ggtgccggca accggacggc gctcatatgg gaaggggaaa acggcgattc gaagtttttc
    12541 acttatcata tgctgcttgc agaagtaaac cggttcagca atgtgttgcg cgggttcggc
    12601 gtaaaaaaag gcgactgcgt ggcgattttc ctgccaaact tagcggaagc ggtgattgct
    12661 gtgctcgcat gcttccggat tggcgcgatt tacaatacga ttttttccgg atactcggaa
    12721 aaatcgctga aagaccggct tgtgaatttt gaaccgaaag tcatcgtgac ggccgatgca
    12781 accgaacgaa gagggaaaaa gatttttctt aaggaaaaag tcgaccgtgt tgttccggac
    12841 attccgtctg tcaaagcggt cgttgttgtg gaccggcttg ggacggatgt caatatgcag
    12901 gcgggccgcg actgttggtg gcatgaagaa acaaggaagg caagcatcca ttgtgaaccg
    12961 gagcggctgg aagcgaacga gtatggcatt gtgttttaca caagcggcac gaccgggaaa
    13021 ccaaaaggcg ttgtccattc cggcatggcg tttgtcgtac aaaattacat ttacgcaaag
    13081 taccatatgg accatcacga tgacgatgtg ctctggtgct cggcggatat cggctggctc
    13141 acgatgcata tttggggcat tgccggcgcg ctttcaaacg gtgttacaac catcttttac
    13201 gaaggggcga ttgattatcc ggaaaaagac cggttttacc agatcattga aaagtaccgg
    13261 gtgaataaat tgttcaccgc tccaactgca ttgaggatgt tgaaaagcat gggggagcgt
    13321 ccgcttgaaa aatacgattt gtcatgcctt gatgtcgtct cccttgtcgg cgagccgttt
    13381 gatgcggaaa catggcagtg gacatatgaa gtgctcggca gaaaaaagat ttgcgtgaac
    13441 aacacatggg ggcagacgga aacagccgga tcgccgcttg ccggtgccgc ctggctgacg
    13501 ccgatgaagc cgggttctgc gggcaggcca tttttaggcg ctgtaatcgg tgtcgtcgat
    13561 caggaaggaa atccggtacc acgggggacg ctcggaaacc ttgtcattca aaagccgttt
    13621 ccgatgctgt gccgcacgct ttggaaagag ccggaacgct atcttggctc gtatttcagc
    13681 caggtagacg gctgctacta tgcaagcgac ctggcgatga tcgatgagga tggctacgta
    13741 tgggtcaccg gccgttcgga tgatgcgttc aatgttgcag ggcacaggct gagcacgatg
    13801 gaaatggaaa gtgcggtgct cgaaaccccg ggtgtatctg aaaccgctgt cattggcgtg
    13861 ccggatgaaa tcaagggcga ggtgccggtc tgctttgtgc gtttgagcga cgggacggag
    13921 gaaagtgaag aactgaaaga agcgatcaag gcccggattg tcgatcaaat cgggaaaatt
    13981 gccgtgccga aaacgatttt gtttacggac acgttgccca aaacagtgag cgggaaaatt
    14041 atgcgccggt tgttaaagga aattgtcgta aacggggcgg ctacagggga tatgaccggt
    14101 ctcgaggacc ccgcaaccat tgcgcgcatt gaacagctgg tggccagtcg cagggcggaa
    14161 agataaaaag gaaggttcgc ccacaggttt gcgaaatcaa tgtttttgac agggaaccgg
    14221 ccgggccgcc agtaaaaaga agggcgttac tgtttgcccg ccggtccctt gcagcgtttt
    14281 acagggaatc ggaagcgaac tggaaaaagg agcatgcggc ggttgatttt ttcgcaatcc
    14341 cggcggctgc acctgaaaag tcagcaagaa tgcaaaaaaa ccggcgcacc ggattatcct
    14401 gcgccgcaaa aggaggaagc ctatggattt cgaattgtct aaagaacaga ttatgctgca
    14461 ggagatggtt cgggactttg ctgagaagga gatcgaaccg tatgcaagag aagtagacga
    14521 aaccgggaaa atgcggatgg agacgtttca aaagctcggc aatctcggcc ttttaggcat
    14581 cccttttccg gaaaaatacg gcggagcagg cggggatacc atctcttatt gcatcgcggt
    14641 cgaagaaatc ggcaaggcat gcgggggaac agggctcagc tatgccgcaa atacaagcct
    14701 cggcgcaagc ccgatctact atttcggcac cgaagaacag aagcagaagt ggctcgttcc
    14761 gatggcaaaa ggcgaagcgc tcggcgcatt cgggcttacg gaaccaaacg ccggatccga
    14821 tgccggcgga acaaggacaa aagcggtgct tgacggcgat gaatgggtga tcaacggcga
    14881 aaaatgctgg attacaaacg ccgaatacgc ccgccaagtg atcgtgacag ccgtaaccgg
    14941 caaaagggaa aacggtcgta acatcatttc cgccatcatc gtgccgaccg atgcaccggg
    15001 cgtgacgatt acaagcccgt atgaaaaaat gggcgttcgc ggatccaaca cgtgccagat
    15061 cgtgctcgaa aacgtccgtg tcccgcgtga aaacttgctt ggcgacgaaa agaaaggatt
    15121 cagccagttt ttgtacacgc tggacggtgg acgcatctcc atcgccgcat tatcggtcgg
    15181 gattgcccaa gctgcattcg aaaaagcact tcgatatgcg aaagaacgga tgcagttcgg
    15241 ccaagcgatt tcaaaattcc aggcgatcca gttcaaactt gccgatatgg cgatggaaat
    15301 cgatcttgct cgcaatgccg tgtacaaagc ggcatggcta aaagatcagg gaaaaccgtt
    15361 tagcaaagaa gccgcttatg caaaactgtt tgcgtcggag atgggattcc gcgtctgcaa
    15421 ccaggcgatc cagatccacg gcgggtccgg ttatatgcgc gagtacgacg tggagcgtca
    15481 tcttcgcgac atcaaactga tggaaatcgg cgaaggcaca tccgaaatcc agcggctggt
    15541 tattgcccga aagcttggct gctaggcgaa aagatagaaa accatccatg cgttccacaa
    15601 attaaactgc ttttgcatga tacacggatc cgtttcaaag atttcaagct gtctttgcat
    15661 tttttaacat cgagaatcag cgatgagatg aaaatggctg tcggaatctc aaatgcgagt
    15721 gaaatatgag aggccgggaa atcacaaaat ttttgaagca aattgagcag aaaggagcgt
    15781 tgccatttgt tcaaaaaaat tctgattgcc aacaggggag agattgcgcg gcgggtgatc
    15841 cggacgtgta aaaagctcgg tattaagtcc gtagcggtgt attccgaggc ggatgcgggg
    15901 gccctttttg tccgcgaggc ggatgaagca tattgcatcg gcaaatcgcc tgtcaatcaa
    15961 agctatttaa atgccgacgc gatcatccgg gcggccaaag aaagcggggc ggaagcggtc
    16021 catccgggtt acgggctttt gtccgagaat gcgccttttg cccggaaatg cattgaggcg
    16081 gggctcattt ttatcgggcc ttctcctgca atcattgctg cgatgggcag caaaattgaa
    16141 gcgcgccgta ccatgaaagc agcaggcgtg ccggtgattg aaggggtgga tgatccgctt
    16201 gaagatgaag aagcggcggt ccgggcggct gaaaaaatcg gttatcccgc aatgctgaag
    16261 gcttcggcag gcggcggcgg aatcgggatg caggtggtcc aaaccgaaaa agagctgcgc
    16321 aaagcgtttg ccggcaacaa aaaacgggcg gaaatgtttt tcggggacgg cgcgatgttc
    16381 attgaaaaat atattgaaga accgcatcat gtagaaatcc agattctggc agaccaatat
    16441 ggaaacgttg tgccgcttat ggagagggaa tgttcgatcc agcgccgcca ccagaaagtt
    16501 gtcgaagaag cgccatcgcc ttttatcagc gaagcgaccc ggcaaaagat gctggatgcg
    16561 gcagtaaaag cagcaacatc catcggctat ataaatgccg gcacgatgga aatgatcgtg
    16621 gaccggggcc agaatttcta ttttcttgag atgaatacaa gattgcaagt ggaacatccg
    16681 gtgacggaag aaattaccgg gctggacatt gtggaagagc agttgaaaat cgcttcaggc
    16741 gaacgcctca cgatcacgcg ggagacgctc aagcggaacg gccacgcgat tgaagtgcgt
    16801 atttatgctg aagatccgaa gacgtttctg ccatcgccgg gcaaaattac agctttccgg
    16861 ctgccggaag gggaaggcat ccgcaacgag acggccgtgg aagcgggttc tgaagtgacc
    16921 cctttttacg acccgatgat cgcaaaactg attgcctggg gcagctcgcg cgaagaagct
    16981 tgcaaaagga tcagaaatgc gcttttaaac tatcaagtgg aagggattaa aacgaatatt
    17041 ccgatgctga ttgataccgt gcgccacgaa caatttttaa aagggtacac aaccacgcat
    17101 tttgtcaatg actttttaaa acaagcggag tcccgcaagt aggcgcaccg gccggttaaa
    17161 aggcgccagg ggcccgaaaa ggggggaatc cgaaagaaag agggctgcca tccctttcaa
    17221 tgatatgccg gctttttaaa ccaggcagag cccccgtatg aagatggccg gatgagggga
    17281 ggcagggaga acatgcaaaa aggtcccggc cattacccga tttgacagtg actttctaaa
    17341 acaggaggaa aagcagatgg aaattacagc aagtatggca ggaagtgtct ggaaagtgct
    17401 cgtaaaggaa ggcgaccagg tgaaggaagg cgacgatgtg gtcgtccttg aatccatgaa
    17461 aatggaaatc ccgattgctg ccgaggaaga cggcacagtg gtaaaaatcc atgtccagga
    17521 aggcgaattt gtcaacgaat ccgatgtgct ggtggaactg gagtagcgca atttgctgaa
    17581 ggaggcgggg atgtgaagct gcctgaaaaa gtgaccgtga aagaagtcgg gccgcgcgac
    17641 gggctacaaa atgaaaaagc ggtcgtggcg acagcagaaa aagttgcatg ggtgaacgca
    17701 ttgtcggata cgggcctgac gtacatcgaa gcaggatcat tcgtccggcc ggaatggatc
    17761 ccgcagcttg ccgataccgg agcggtgctg gaaaaaatca gacggaagcc gggcgtgaca
    17821 tatgccgcgc tggtcccgaa cgtgaggggg cttgaacggg cattaaatgc aggtgtggat
    17881 gaagtgagcg tcttcatgtc ggcaagcgaa ggacataacc tccgcaacat taataaaacg
    17941 attgcggaaa cctatccggt cttggaaaaa gtggtgaagg aagcgaaaaa cgccgggaaa
    18001 tcggtaaggg gatatatttc gacggtgatt gcctgcccgt atgacggacc ggtttcccca
    18061 aagcaagtaa aagaagtggc cggccgcttg tttgcgatgg gcgtggatga aatttctctc
    18121 ggggatacga tcggtgccgg cgtgccgacg gatgttgagc ggttgctcgg cgaactgctg
    18181 aaggattttc atgcaaggca actggcgatg catttccacg atacaagagg gacggcactt
    18241 gcgaatgttg tcaagtcgct cgaaatgggg attactgttt ttgacagcgc agcaggtggc
    18301 ctgggcggct gcccgtatgc gaaaggggca gccggtaatg tcgccacgga agatttgctg
    18361 tacctattcg cgcagatggg cattgagacc ggcgttgatc ttggccgcat catccaggcc
    18421 gcacagcaga ttgaaaaaac gatcggaagg ccgcttgcaa gccaccagat ggaaatttac
    18481 aggatggcag gaggagcata acgggaacgt tttgccggaa aaagcaaaag gcactggcgt
    18541 ggtgatccag aacagcccgg aaccgcaaaa cagattgcaa agccgatcgg aagggcgctt
    18601 gcaggcaaac aggcaggagg ggaaaaagaa catgacagga acagttttat tggaaaaaca
    18661 agatggcatc accgtgatga cgttgaaccg gccggaagct gcaaatgcat tatccaaaga
    18721 aatgctttcg gatatgcatg aagctttatc ggaagtaaaa aaagaccaga gcacgcgcgt
    18781 tgtgatcctg accggcgccg gggaaaaagt gttttgcgcc ggagcggatt taaaagagcg
    18841 gaaaggcatg aacgaggaag aggtgctgca ggccgtacgg aagatcggtg cggttgtaaa
    18901 tgaaacggcc gcgctgcccc agccggtaat tgcggcgcta aacgggtcgg cattcggcgg
    18961 tgggctggag ctggcgctgg catgtgatct tcgcattggc gcccgcgaag caaaatacgg
    19021 gcttaccgaa acgtcgctcg cgatcatccc gggggcgggt ggcacacagc ggctgccaag
    19081 actcattggg gttggtaaag cgaaagaact gatctatacg gcgcgacggc tgactgctga
    19141 agaagcagcg gcaatcggcc tgctcgaata cgctgtgccg cgtgcagcag taatcgaaaa
    19201 agcgtttgaa ctggcggggg aaatgcaaaa aaacggcccc attgcactta gacaggcaaa
    19261 aacggctatc gatcaaggga cagagaccgg cctttcagca gggctgaaaa tcgaagaact
    19321 cgcctacaac gcgctcattc cgaccgaaga caggctcgag ggcttgcggg cattcgcgga
    19381 aaagcgcacc ccggtgtata aagggaggta atgcaatgga ctacgaaagc aaaaaagcag
    19441 aaattttaaa gggcggaaag gaaaaatacc accaaaaaaa ccgcgaacag ggcaaatggt
    19501 ttgtccgcga acgcttgcga atgctgttgg atgacgggct caaggctgaa gacgggatgt
    19561 ttgccaatgt ccttgcgggg gacctgccgg cagacggggt cgtcaccggg ctcggaaaaa
    19621 tcggcggccg caccgtttgc gttatggcca atgattcgac cgtaaaagcc ggttcgtggg
    19681 gctggcggac ggtcgaaaaa atcatccgta tccaggagac agccgcgaaa ctcaactgcc
    19741 cgattttgta tctcgtcgat tccgcaggcg cacggattac cgatcagatc gagatgttcc
    19801 cgggcagaag aggagcaggg cggatttttt acaacgaggt gcatttgtcc gggaaagtac
    19861 cgcaaatttg cctcttgttc gggccgtctg ctgccggcgg ggcgtatatt cctgcatttt
    19921 gcgatattgt cgtaatggtc gagggcaatg cgtccatgta cttaggctcg ccgcggatgg
    19981 ccgagatggt gatcggtgaa aaagtgacgc tcgagcagat gggcggcgca aaaatgcact
    20041 gcaccgtttc gggttgcggc gatgtgctag tgaaaacgga agaagaagca atccgttatg
    20101 tgcaaaaata cttaacctat tttccggaca atttttccga aaaaccggca agaacagaag
    20161 caaaggcgcc ggctgcgttt gaaaaaacga ttgaggaact gatcccgaaa aatgaaaatg
    20221 ccccgtttga catgtaccag ctgatcgagc ggattgtgga tgaagattcg atctgcgaga
    20281 ttaaaaagaa gtttgcgccc gaactgatta catgtctcgc ccggattggc ggccggcctg
    20341 tcggaatcat tgcgaatcag ccgcgggtga aaggcggcgt gcttttccac gacagcgccg
    20401 ataaagcggc aaagtttatc catctttgtg atgcgttcca tattccgctt ttgtttctcg
    20461 cggatgtccc cggcttcatg atcgggacgc aagtggagcg ggccggcatt atccgccacg
    20521 gggcaaaaat gatttttgcg atgagcgaag caaccgttcc gaaactgtcc gtcattgtcc
    20581 ggaaagcgta cggtgccggt ttatacgcaa tggcaggccc ggcgtttgaa ccggactgct
    20641 gcattgccct tccgtctgca tcgattgcgg tcatgggccc tgaagccgcg gtcaatgccg
    20701 tatacgccaa taaaatcgcc gcactcccgg aagaggaacg gccggcattt ttcgcggaaa
    20761 agcgggcgga gtacgtgaaa gacattgaca tttaccggct tgcttccgaa ctggttgtgg
    20821 atgacgtcgt accgggcaat gaactgcggg aagaactcga acgtcggctt gaaatgtaca
    20881 gcgggaagca ggaagaattt tcaaaaccaa agcacccggt atacccggtt taacattgaa
    20941 aagcagctgc aggggcgcag ctgcttttca atacggctcc cggaaaacaa aaatggcaac
    21001 ggaaaaagac caatggtgcg cttttcttcc ttaaaacggg gtatgaatgt attatcaaat
    21061 gccaacgagg aggcgcatct atggaatttc ggaaagccaa tctggatgat cttcatcatt
    21121 taatagagct tagaaagcag cagcaagttg cccaaggcat cgaaccgaag acggacattg
    21181 atgccgattt ggaaaagttt tttcaaaaga aattaaaaga aggctccatg gtccaatggc
    21241 ttgcggaaga cgaaggagaa atcgttgcct gcggggctgt cattttttac gaatttccgc
    21301 cgagctatgt gaataaaagc gggaagaaag cctatattac aaatgtttat acaaaagaag
    21361 aataccgcgg ccaggggatc gcgaaagaat tgatggaaaa actgatggat gaggtgaaaa
    21421 aggctggcat ctccaacatc tggctcggcg cttcggaaat gggcaagcca ttgtatgaaa
    21481 aattcggttt ccaggaagtg gatgaatgga tggaactaca tttatgatga aaggagagaa
    21541 tgagaaaaac cggtaatccg attccaaatt ctattttcct tttcatttta ttatgaaaat
    21601 tatataatgt tttaaaggag tcggaaaaaa tgtctgattt tgttcacgat acaaattcca
    21661 atgtctattc agatggaagt catgaatatt taaaagtcaa ttccttcata ttaaaaataa
    21721 gtttcagtta aaagatcagc agttagctac actatttggg atttccgatg agaaaactac
    21781 aaaaattctc tctggaaagc catgctactt tgatgaaggg gagttaaaaa gaatccatta
    21841 tcgtttaccg tttttaagta caggattctc ttttatagac tcaaaagaga gaatgagagc
    21901 gataatagag gctaatttga taggagatta taatctttcc tatgaaacat taggtaagta
    21961 tgccaatgtg ccttgcgatg tgcttaaagc tttttgtgaa ggaaatgatc atattgatat
    22021 tgatcatttg atgaatattt gcgtaaattt gttaatgcta tcttttgtat taagacctga
    22081 actttaattc attgtttacc gatcaaattc catccacggt ttcttttgag tgctactttg
    22141 atttgtccaa agaaacactt agaaaataag gccttacatt tctgtgcctt ccaaagtgta
    22201 tattttgaac ttccccatct gccggtctat acttaaaata gtaaggagga atgtacgatg
    22261 tatgaaattg ccattattgg agctggtccg gccggggcaa gtgccgccat ttttacggcc
    22321 aaagccggga aaagcacagt gctttttgat ggtggcacga gcgctaccaa gcgggctttg
    22381 ctgaaaaatc actacggcgt aacagaaata accggaccag acctggtcga aaccggtaaa
    22441 aaacaggcag cgcaattcgg ggccgaactg gtcgacgaaa aagtcgaatc aattgaaaaa
    22501 acggaaaatg gttttaccat taaaacagaa caagggtcgt acgaaagcaa atacgttatt
    22561 cttgcaaccg gcatgattgc aagcctcggg gaagcccttg gcgtcaaagc caaaccggca
    22621 acagaaccac gcgtaaaaac cgtttttgca gtggatgcgc aaggaaaaac gaatgtcccg
    22681 aatgtatggg catgcggcac ggttgccggc gtctccatgc acaccattat cacagcaggc
    22741 gacggcgcta aagtggctgt caacctcatc agtgaaatcg acggcaaacg ctgggtcgac
    22801 cacgatgttt taggaaaata agccgttgta aacgaaccgg gcaaaattcc gcccggtttt
    22861 cgtttgcttt ttttcaatgc gggctggaac tgaaaagaat tcgtcgcaga tcaagcattc
    22921 tgacatgctt attgtttttc caaaatcaaa ccacccactg caaagccggg cactggggat
    22981 gcagccggta cacgcgggat tcaggcaatc atcaaacctt ttttgcgtaa agccgtcttt
    23041 cctattccat gggaggattg ttaaaaatgg aatttatgat tacaatagat aaaaatatcc
    23101 aaaaaataaa ccgaattttt aaaaaacggg gagttgaggt tcatgtatcg aatttttcaa
    23161 tgtggatttg tgatggcgtt tacaggacta tgtatgatgt ttttggttca tcttgttgat
    23221 ggttattcaa ctgtagagct cggaaactcg ctgattagtc aaatattatt gattccaaga
    23281 ttttttttga tttttggtat attattattg attctctctt tcattatttg gtttagaaat
    23341 tgggcgaaat ctaaggcaaa aaaaatttca tgagttttaa agtagagtag gcttagttgg
    23401 gcctgctttt tttgcggcga gcatctgtat tctgaataag tgaggatgtt attgcgataa
    23461 acacggctcc cgaaaccagg aaaacaatcg ggtcaaatta taattccaaa aaacggtatt
    23521 agccaacaat aggtatgtta tttgtaaaat gatttagaaa gaatctgcca aaatatacca
    23581 ctatcttttc tattgaattt atagtaaaat aaactgttag cacatagaaa ggaggcgaac
    23641 gtcatggcaa agaaatctat gattgtcaaa caaaaacgtg agccgaaatt taaagttcag
    23701 gcttacacac gctgcgagcg gtgcgggcgt cctcattcgg tataccggaa attcaaactt
    23761 tgccgcatct gtttccggga acttgcgtat aaaggcgaga ttccgggcgt aaagaaatcc
    23821 agctggtaag ccttccccgc tccccttttt tcggggcacg ggatacatat ccccgttctt
    23881 tccgcatctt tgtaaattct ttaatccctc ttcatcataa tttaacaaat cggtggtacg
    23941 ctaaaatcag cggggatggc aagcgtggcc atcatcggta caccgcgtag gcggagcggg
    24001 taccttgatt tccagtacag ccggcatgtt tacttggaaa tccaaaacct ttcccttctg
    24061 atttttttaa aaggaatttc ggcatgcatg cagaaatttt tcttttatag aaaatgaaaa
    24121 aaggggagga tattcgaaaa cgccgtcata ggcaaaactt tttatgacga gagatgtgtc
    24181 aagtttttct cgattgtgag atgttgaagg caggcttcca atgcgatcga gaaaattttt
    24241 atacatagga gaccgttgtc aaaactgaat aggtagattt tatgccaaca ctccactcaa
    24301 tatgctacta ttaaatcaaa gcatttggaa cggagcaatg gcaatgaaca cgaaccaaga
    24361 cttttttacc cgtaaaaaag aggagtccgg aattgtggtg aatgcagtgc agcaagaggc
    24421 cgtaaagcaa acggaaggtc cgcttttgct tttggcttcc cctggctccg gaaaaacgac
    24481 aaccgtcatc atgcggatcg gctatttaat tgaagaaaaa ggggtggcgc ctgcacggat
    24541 taaagccatt acgttcagcc gtgccgctgc cgctgacatg aaagaccggt tccaaaagct
    24601 ttttccgaat cttccgcccg ttgatttttc aacgatccac agccttgctt ttgaactcgt
    24661 tcgcgttttt ttcagacgga ccaatgtccc tttcttgctg attgaaggcg aggcggggcc
    24721 gtaccataag aaaaaaattt tgcgggatgt atacaaggcc attaacgggg agaggatcac
    24781 ggaagaccag ctggaggaac tgcagacgta tatcagctac atcaaaaaca agatgatccc
    24841 gcctgcaaaa tgggggaaga ttgcgacagg tgtgccggaa gctgcccgga ttttaaaaga
    24901 gtatgaggcg tttaaaaagc agggtaccgg tcagctgctt cttgattttg atgatatgct
    24961 gacgcatgcg aatgaaatat tcaggcgtga tccgaatctt ctctgtatgt atcaggggcg
    25021 ttatgactat gtgctgacgg atgagagcca ggatacctcc atggtgcagc atgccattgt
    25081 tgaaaaactt gtgcggcggc accggaattt gtgcgtcgtc gccgatgatg accagtcgat
    25141 atacagctgg cggggtgcgg agccgtccta cctgttgaat tttaaaaagg tgtatccgga
    25201 tgcgaaaatt ttatttatgg aacaaaatta ccggtcatct caagaggttg tcacggctgc
    25261 caacctgttt atcaagcgca acaagcaccg ctatgataaa aacatgttca cggaaaaccc
    25321 gcctgccggg ccgatccggt ttgtgcgcct gccggattat aaataccagg caaaatattt
    25381 ggcccaaaac attgccgcat ccgaaaattt ctcggaaatt gccgtgctgt accgcaacaa
    25441 tatgtcttcg attgccctga tcaacgaatt tgaccgggaa gggattccgt tttatatcaa
    25501 agataccgac aaccgctttt tctcccactg ggtcgtccag gatattttga atgtgatgcg
    25561 gctcacgttt accgataaac gggcggatat cctcgcgcag gtccattcga aactggacgg
    25621 ttatattacg aaacagcaga tggaagcggt aaaggggatc cataataacc aatctgtttt
    25681 tgacaattta atccaatacg cgcatttgaa ggactaccag gtccaaaaag tgcgtgaagt
    25741 aaaggagacg ctccgggaaa tgcggggcat gccgccgctg gatgcgattc atgtcattcg
    25801 cggcaggctc ggctatgaaa aagcgctcga aaacatgtgt aaaagattag gatttcgaaa
    25861 ggatcccctg attggcattt taaacacact cgaagaaatt gcggacacgc tttccaccat
    25921 ggaggaattt gccgcccgcc ttcagcactt ggcgcacatt ttaaaaacgg cgaaagggaa
    25981 caaaggccgg catgctgtga cgctttcgac gttccacagt tcaaaaggtt tggagtttga
    26041 aaaggtgtat atgattgact tggttgatgg gatcattccg ggtaacgatg aaaaagaaga
    26101 tgatttactg atggaagaat cggtccgtct tttttatgtg gcaatgacgc gcgcgaaaaa
    26161 gtcactggaa atggtcagct atgaaaaacg caacggaagc cgggcaatgg actcaccgtt
    26221 tgtggcagcg gtgaagggaa ttgtcaacag tgttgaaaag gccggaaaaa caaagccaga
    26281 aatagaagtt gcccgaatcg gcaaaaagac ggtctccatc ccgcagaacc cgaatgccat
    26341 taaggacgca tccgcttttg tggccggtaa aaaaatccag caccgtgtgt ttggtcatgg
    26401 tgaaattgtt gatattgatg gtgacaccct tgccatccgg tttgaaaaac ggacgataaa
    26461 actgtctgcc ctcacctgca tcgaaaaagg gctgctcgag gaagccgatc tgtaatcgtg
    26521 tgtggaaaaa cggaagcgga tataaaaaat gccgggaatt tcccggcatt ttttatatcc
    26581 ctgaccgccg caacaggctc acgttgtacg gaggcaaggg attcggcgat caagtcctgt
    26641 gccccttttt attgaattgg aacgccccag gccatttgga tgactgcaac aaaggtgcca
    26701 tccggttggt gccccgtgcg aatgggagca gagcctcctt gctgtttggc agcattcccg
    26761 agatttactg ctcgcggatg ctgttttcct gcgtatttct ttttttcctc caaatcagca
    26821 gctgttctgt caaaatgccg accacagatc caaggattaa gccgttgttt aaaaaagtag
    26881 cgatcatcat tggcaaatgt tcggtcgcat gagccggcaa aaacatcgcc ccgattccga
    26941 ccaggaagga gatgcctgct gttgtgtggg caatctcttt gtccgggctt ttttcaagat
    27001 catttaaggc aaggccaacc aattgtgtga agaccacaaa ggtaacggca taaccaaccg
    27061 gcgcgggaat cgcagacatg atatgcacga gcggtggcag cagagcaatg atggaaacga
    27121 aacaagcacc atacaaaaat ggtttcagca cttttatacc ggtttgtgca acatagcctg
    27181 ccgctgctgc aatcggaacc gcaccgacag cggaaaagat gccggcaagc agctggttga
    27241 tgccggatat gaacagactg ctccgcaccc gctcttggcg gactcccgtc acatttccca
    27301 tgacgcgcac agacgtaatc atattcgcag ttaacaaaag cccgatgaat acaccggttg
    27361 tgacggcacc ggaatcaaaa cgcggttttc caaaatcaaa cacagcggga agagagaacc
    27421 agctttcccc aaatgtaata gccggtgctt caccgaaaag cgcgaacaaa atccagccac
    27481 aaatcaagcc gagcatgatc gaatattgct tgacccacgg tttctttaca tggccaaaat
    27541 agaatgtaag caatacggtg acaaggctca aaacggcaac aagcggccgg acttcctgat
    27601 gggcacccgt aatgccgagc atccctttca taaaagagcc gctcaactgc agcaccaaaa
    27661 gcagcaaata gataaatgtt actaccggcg taaacagttt atttaattgg tccacaaagc
    27721 cggtaaaagc gagtagaaag aaaaagatgc cggttacaat cagtgcgcct gccaaatatt
    27781 gcagagattc agtgcttgaa ctgtacaagc tgccgacaag ccctgcataa atggcaaaca
    27841 cgctccacca cagcccggcc ggcccttcat tgatgggcat tctgtggccg aaaattcctt
    27901 gcaaaaggcc gccgatcccg agtacaaaaa gcgtccgctg cacaaacagg gcagtctcac
    27961 ctgcactgaa atggaaagca tccgcaatgg caatcggggc cgcgatcgac ccggcgatca
    28021 taaatgccat ccattgcagc gacgaaatca atgttttcat agacacaccg ttctttccgt
    28081 tcaaaaaatg gaaaatacca gtaaatataa ttatagcaaa acaggtttta cattttaaac
    28141 ataatacact ttgcggacga gggagggata gcgggcatgg cggatagcgg cataaacagg
    28201 ggttgcaaac cggacggggc gcgggttaag ccatgttttt tgcctctatt taaatgatat
    28261 atatgtggca ggggctaagc tatgtttgga tccgcaaaaa atttctgggc gatcttcatg
    28321 cagaacgctt tttgtttgtc actaaaagag ttgcggctgc ctttacttag gcatgctatc
    28381 tcgaaaaaaa ttatgatgga taatttttgc tggtgctacg tggtagcggc atggccggtt
    28441 atgttgagga agcgaggtca aaaggtgttg tttcttaaca tagagcgcgt ctacgttaag
    28501 a
//
