LOCUS       c00233_gnlPro..         4486 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GEDPCNNE_233.
ACCESSION   c00233_gnlPro..
VERSION     c00233_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:05:24
            Original ID  :: gnl|Prokka|GEDPCNNE_233
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4486
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4486
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[559:4485]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      560..4485
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4486
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4486
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..560)
                     /locus_tag="ctg233_1"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILD"
     CDS             complement(560..1123)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg233_2"
                     /sec_met_domain="ALS_ss_C (E-value: 2.2e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             complement(1142..2839)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg233_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-48, bitscore:
                     152.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDLITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNT
                     LNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVAWAIARAFYIASSGRPGPVVLD
                     FAKNAQVEKTKYEPTKQEFIRSYVPVPDTDEESVKAAAELINNAERPLVLVGQGVELGS
                     AQEELRIFIEKADMPAGCTLLGLSALPTDHPLNKGMLGMHGNLGPNINTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDIAVLGDCKKTLAAVTGLLKKNR
                     HTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVRAVSEATRHEAILVTDVGQNQM
                     ISARYFKYTRERSIVTSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVF
                     SREELKAAIDEMLSTDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             complement(2887..4485)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg233_4"
                     /sec_met_domain="ILVD_EDD (E-value: 4.3e-204, bitscore:
                     666.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADSVEYMVNAHK
                     ADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLIDAMIKSADDS
                     VSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATHENRTKLFED
                     AAKLIVENAMKYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLHLLAVAHEAG
                     VDFKMDDIDMLSRKTPCLCKVAPNTQKYHIQDVNRAGGIIAILAELAKGGLIDTSVLRV
                     DGMSLAEAIDQYSITSPNVTEKAMSKYSSAAGNRFNLVLGSQGAYYQELDKDRANGCIR
                     DLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEAACEGILGGR
                     VVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHV
                     SPEAAAGGNIGKIVDGDIIEIDIPARTINVRLTDEELAARPMTPVTRDRYVPKSLKAYA
                     SMVSSADKGAVRLID"
ORIGIN
        1 aagtcaagta tgtgctcgat ataacgaata ctgtttacgt gtccgttaat atcgatatca
       61 ctgtattttg ccgtcagcgt cgcaacaggc tgattgcttg tcaccttgat acgcgaaggc
      121 ttttctatcg ggcagggttc atcgcatata taatcgacga tgcttcctcc atgcaatgcc
      181 aacagatcgg caggcttacg ggtattcaga ttgatcatcg cccatacgga acgggcatag
      241 ccgatcttct ttccatcctt gtcaatgacg gcaaagttac ggtcggtaaa gagacgatag
      301 acattctcca cccatgtctg aaccgagaac ttctcgtact ggtaaggcat ctcatccagc
      361 tcgatagcca ggcgggaaag cacccatgtg taattgtcct cgttcagcgt agcaatacca
      421 aatccacggt cgctggcatg aaaacctgcg caattcaaca gatgatttcc cagcacgccc
      481 atggtcaggc ggccgttaaa atctacgtga aacggctctg ccacaaactg ataagtccct
      541 attttatttt cttcactcat tactcctgtt cctttttact ttgcttatac ttcgcttcct
      601 gtccgtccag gaactcattc acacgttcga aacagctggt agtaatagcc acacgacccg
      661 aacggacaaa ttgcagcaca catttcaaag cccgaagttc ctcgtaaagg gaagtaatct
      721 cttcactcat gccgttcttc tcgacgatag agaataccgg attcacctct acaatgcggg
      781 cattatatct gcggatcact ttagatgctt ccggagtctc ctgaaaagca ggagtagata
      841 ccttatataa ggctatctca tggaaataaa tctcgtcttc agtaaaatag tgcgcctgaa
      901 tcacatcaat cttcttttcg atctgcttca ccaccttttc aatagtgtcc ttatcagtcc
      961 acgctgtgat cgtatattta tgtactcctt taatggaaga agcagaaacg ttcaaactct
     1021 cgatgtttat ttgccgacgg gtaaatacag cggtcacctg attcagcaat ccggctatat
     1081 tttcagaatg aactataatc gtatataatg tcttatcact cataactttc taaattaagg
     1141 attaacattc cagcaacatc tgattgactg aaccgcctgg aggggtcatc gggaggacat
     1201 tgccttcttc taccacacag gcttcgagca ggaacggccc gtctgtcgag agcatttcgt
     1261 cgatagccgc tttcaattct tcccgtgaaa agacacgttt ggaaggaata tcgtaggcgg
     1321 aagcgatttt catgtaatcc ggattcagca tcggagtaaa tgaataacgg cgattaaaga
     1381 acatagcctg ccattggcgc acgttgccga gataattgtt gttcaggcag ataatcttca
     1441 ccggagcttt ctgttccatg atcgtaccca gctcctgaat gttcatttgc agtccgccgt
     1501 cacccataaa tacacataca gtgcggtcgg gacggccgaa agtagctccg atagctgccg
     1561 gaaggccaaa acccattgtg ccgagtccac ccgaagtaac gatactacgt tccctggtat
     1621 atttaaagta gcgggcagag atcatctgat tctgacctac atctgtcacc aatatggctt
     1681 cgtgacgggt cgcttcgctt accgcacgca ccacttcgcc catactcagt gaatccgttg
     1741 caggatgaag ttcaggacga atgacttttt cttcctctac cgcttcatat tccttgaaac
     1801 tatcgaccca ctcggtgtgc cggttctttt tcagcagtcc ggtcacagca gccagcgtct
     1861 ttttgcagtc gcccaaaacg gcaatgtcta cctttacatt cttatttact tccgccggat
     1921 caatatcaaa atggatcact ttcgcttgtt tggcgtaagt agccagatta ccggtcacac
     1981 ggtcgtcgaa acgcataccg acagcaatca gtacatcaca tttgttagta ttgatattcg
     2041 gtcccagatt tccgtgcata cccagcattc ctttattcaa cggatgatcg gtaggcaatg
     2101 cggaaagtcc gagcaaggta caacctgcgg gcatatccgc cttttcgata aagatacgca
     2161 gttcttcctg agcgcttccc agttccactc cctgtcctac caagacaagc gggcgttcgg
     2221 cgttattgat cagttcggcg gcagccttta ccgattcttc gtctgtatcg ggaaccggaa
     2281 catagctgcg gataaactcc tgctttgtcg gctcgtattt cgttttttca acctgcgcat
     2341 tcttggcaaa gtcgagtacc accggaccgg gacgaccact actggcaatg tagaaagcac
     2401 gtgctatcgc ccaggctacg tcttcggcac ggcgaatctg atagctccat ttagcgattg
     2461 gctgagtgat acctacgaga tcgacttcct gaaaagcgtc tgttccaagg aagcctgttc
     2521 ccacctgtcc tgcaatgaca acgataggcg tactgtctat catcgcatct gcaatacctg
     2581 tgatcgtatt ggttgctccg gggccgcttg tcaccaagca aacaccgact ttacccgata
     2641 cacgggcgta gccttgtgcc gcatgggcag ctccctgttc atggcgaacc aagatatggt
     2701 tcaatgtatt ttgatggtcg tacagggcat cgaacgtagg catgatggaa ccgccgggat
     2761 aaccgaaaat ggtagtcact ccctgatgtt ccagagagcg catcattgcc tctgcgcctg
     2821 ttattaagtc cttactcata gttctttaat ggataatgga tgattcataa tggataatga
     2881 agtggatcag tctattaatc tcactgctcc cttatcggca gagcttacca tgctggcgta
     2941 tgctttcagg ctcttcggca cgtaacggtc acgggtcacg ggagtcatcg ggcgggcagc
     3001 cagttcttca tctgttagtc gcacgttaat cgttcgggcg ggaatgtcga tttcgatgat
     3061 atctccatct actatttttc ctatattacc tccggcggcg gcttcgggag aaacgtgtcc
     3121 gatactcaat ccggaagttc caccactgaa acgtccatcg gtaatcaagg cacattcttt
     3181 gccgaggtga cgggatttga tataagaagt cgggtaaagc atttcctgca taccgggacc
     3241 gcccttcgga ccttcgtgcg tgatgacgac aacgtcgccg ctgacgactc ggcctccgag
     3301 gatgccttca caggctgctt cttgtgagtc gaatactttg gcaggtccgg taaacttcca
     3361 gatgctttcg tctacacccg ccgtttttac tacgcaaccg tcctgagcga tatttccttt
     3421 cagtaccgcc aggcctccgt ccttgctata ggcgtgctcc agatcacgga tacatccgtt
     3481 cgcgcgatct ttatctaatt cctgataata agctccctga gaaccaagta cgagattgaa
     3541 tctgtttcct gccgcacttg aatatttgct cattgctttt tccgtaacgt tcgggctggt
     3601 aattgaatat tgatcgatcg cttccgccag cgacatgcca tccacacgga gaacggaagt
     3661 atcaatcaga ccgccttttg ccaactctgc caggatagca atgatgccac ccgcacggtt
     3721 aacgtcctga atatgatatt tttgagtatt cggagcgact ttacacaggc agggtgtctt
     3781 gcgtgacagc atatcgatgt cgtccatctt gaaatcgact cctgcctcat gtgccacggc
     3841 caataggtga agcaccgtat tggtagaacc gcccatcgca atatccagcg tcatggcatt
     3901 gaggaatgcc tgacgggtag ctatgctgcg gggaagtaca ctttcgtcac cttcttcata
     3961 atatttcatt gcattttcca caatcagttt ggcagcatct tcaaacagtt tcgtacgatt
     4021 ttcgtgcgta gccacgattg tgccgtttcc cggaagagcc aagccgatag cttcattcag
     4081 acagttcatc gagtttgccg taaacattcc ggaacaacat ccgcaggtag gacaagcatt
     4141 ctgttcgata ttcgctactt cctgatcgct tacactgtcg tccgccgatt taatcatggc
     4201 atcgatcaag tccagatgct gaccgttcca ctctccggct tccatcggtc caccggatac
     4261 aaatacggta gggatattca ggcgcatggc agccatcagc atccctgggg taatcttatc
     4321 gcagttgctg atacatacca ttgcatccgc cttgtgcgca ttgaccatat attctacgct
     4381 gtccgctatg atatcacggg aaggaagcga gtaaagcatt ccgtcatgtc ccatagcgat
     4441 accgtcatca atagcaatcg tattaaattc cgcagcgaag catccc
//
