LOCUS       c00172_gnlPro..        13085 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GLPJFDAN_173.
ACCESSION   c00172_gnlPro..
VERSION     c00172_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 21:49:22
            Original ID  :: gnl|Prokka|GLPJFDAN_173
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13085
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13085
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3097:7955]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3098..7955
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..13085
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13085
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             119..2041
                     /locus_tag="ctg172_1"
                     /transl_table=11
                     /translation="MGISSPLVDLQHQYDLLQKEYEYEKETYRQQSERTGLRKRVAQGL
                     CWYPVTPGRSYHNSLNQLVIEIERTEDREIEHNFEYGRPVCFFTADISGKFKYLDFSAT
                     ISYVQEDRMVVVLPTPSALMDIQGKSNDLGVQLYFDETSYKTMFSALSDVMRAKNNQLS
                     HLRDVLLGQEKPGQRELFPIRFPWLNRSQEEAVNKVLGAKQVSIVHGPPGTGKTTTLVE
                     AIYETLHRENQVIVCAQSNIAVDCISEKLVDRGINVLRIGNPTRINDKMLSFTYERRFE
                     SHPDYPELWSIRKAIRDIQSNMRKKSREERDTIRNRLSRLKFRATELEVKIDTELFDEA
                     RVVACTLVGSANRVMMNRHFTTLFIDEAAQALEAACWIAIGKADRVILAGDHHQLPPTI
                     KCIEAEREGLGRTLMQKIAHTKPETVSLLKIQYRMHEDIMRFSSQWFYHNELESAPEVS
                     GRGILRLDTPIVWFDTSECDFTENTREETMSRVNRQEAELLVEQLRSYIQKISKERVLE
                     ENINFGLISPYKAQVQYIRKLIKQDAFFKPLRRLITVHTVDGFQGQERDVILISLVRAN
                     EDGKIGFLNDLRRMNVAITRARMKLMILGDASTLTRHAFYNELYNYISQRGKIITINTK
                     QEHEL"
     CDS             2031..2837
                     /locus_tag="ctg172_2"
                     /transl_table=11
                     /translation="MNYKLLVLDLDGTLTNSKKEITPFTRETLLQAQEKGLHLVLASGR
                     PTYGIVPLAEELNMKQYGGFILSFNGGKVIDFMTDKVLFEQALPPDIVPVLYNRSKEAG
                     LAILSYNGKYILSEHPENKYVQYESFLTKMKIKATDDFLRDLHQPADKCLVVGEPEMLV
                     SLEEKLRQELGKRINVYRSEAFYLELVPKGIDKAASLSRLLERTRIKQEEVIAIGDGFN
                     DVSMIRFAGLGVAMANAQPPVKANADRITQYTNDEDGVARFIQELL"
     CDS             3098..4330
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg172_3"
                     /sec_met_domain="HBT (E-value: 1.4e-17, bitscore: 53.4,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDKKEITPRTHAALLKAQQMGVHVVLASGR
                     PTNGVQPLAEALELNHYGGFILSYNGGQIINAQTGELMFEKRIDPAMIPYLNRKAKENG
                     FAIFTYHKDYILTDSPENKHVQEEAELNKMRIIGVENFPEAVDFAPCKCILTSDDENNL
                     VGLENHWKKRLDGVLEAFRSEDYFLEVAPHFINKGNTLAVLMEMLNITTEEVVAIGDGV
                     ADVSMLQLAGTGVAMGNARDSVKACADFTTLPNNMEGVAVAIEKAILATIKPTEVPLDQ
                     LNARAKHALIGNLGIQYTYASEDRVEATMPVDERTRQPFGILHGGATLALAETVAGLGS
                     MILAKPDEMVVGMQVSGSHMSSAHEGDTVRAVGTIIHKGRSSHVWNVDIFTSTDKLVSS
                     VRVINSILKKK"
     CDS             4327..5424
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg172_4"
                     /sec_met_domain="Chorismate_bind (E-value: 1.7e-55,
                     bitscore: 177.7, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPRDFYEIIDTLIKQGRSFAIWRIPGEDRLHFRMQSAGSPCLLY
                     DIKDLNERSGFVIAPFQVTAERPIVLIQPDCFEIPSESDRDFSREKNEFPSNEIEIPSE
                     SEEKERYAYHFSLFTNPLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAVERYIRSYVY
                     LCHTPETGTWMGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQLVAS
                     YIRRQLSTLGITPEEKGPYSARAGEVSHLKSDFFFSLPDSEKLGDVLQLLHPTPAVCGL
                     PKEEAYHFIIEHEGYDRSYYSGFIGWLDPKGKTDLYVNLRCMNILPKTFTLYAGGGLLA
                     ASQLEDEWQETEDKLDTMRRIVGNL"
     CDS             5439..7127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg172_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.2e-08, bitscore:
                     21.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLIEHGVSNIVLCPGSRNSPIVHTLANHSFFN
                     CHSVTDERSAGFFAVGLALHGGKPAAVCCTSGTALLNIHPAVAEAFYQKVPLVVISADR
                     PAAWIGQMDGQTLPQPGVFGSLVKKSVQLPEIHTDQDEWYCNRLINEALLELNHHGKGP
                     VHINVPISEPLFQFTTPELPKVRVITRYQGLNVYDRKYDDLIERLNKYSKRMMIAGQMS
                     LIYLFEKKICKLLYKHFTWLSEHIGNRIVPGLPIKNFDAILYATPEEEKEKLVPELVIT
                     YGGHIVSKRLKEFLRKHPPKEHWHVSLDGEVADLFGSLTTVIEMDPFEFLEKIAYMLEN
                     RQIEYPKAWEYKSRNLPEPEFAYSEMAAIGGLIRSLPAESALHLGNSSTVRYAQLYTVP
                     ETVEVCCNRGTSGIEGSLSTAIGYASASQKLNFIVIGDLSFFYDMNALWNGNLHNNLRI
                     LLLNNGGGEIFQALPGFKMNERTHRYVTASHQTSAEGWATERGFSYSAVHNAEELAAAM
                     SAFTQTEQPSEHPLFMEVFTDKAEDVRLLKEYYHQLKNSSQAQNI"
     CDS             7131..7955
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg172_6"
                     /sec_met_domain="ECH_1 (E-value: 2.6e-82, bitscore: 265.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTE
                     MSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNVKGRGGYVGKDGVPRLNVLDVQKQI
                     RSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP"
     CDS             7993..9051
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg172_7"
                     /sec_met_domain="MR_MLE_C (E-value: 4.3e-30, bitscore:
                     94.3, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKERFYKTEVVPRCLTFKRPAGTSRGVYTTRKLWEVRIRKEDEP
                     SVIGIGECAPLPDLSCDYGVDYEITLSKACLDLEQKGYVDTESLRHYPSILFGLEMAMR
                     HYEQGGWRHYDTPFSRGQAGIPINGLIWMGDYKYMLEQVEEKMKEGFRCVKLKIGAIDF
                     DRELSLLKHIRAHFSAKEIELRVDANGAFTPSEAMDKLKRLAEMDLHSIEQPIRAGQLE
                     EMAHLAAESPLPIALDEELIGCNAPDEKRRLLETIHPQYIILKPSLHGGIAGCTEWVHL
                     AETILGSTPERPKWWVTSALESQIGLNAIAQWCATLGNPLPQGLGTGEIFKDDKHRLIQ
                     RKGDTIWFSNDL"
     CDS             9055..10128
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 51.4; E-value:
                     2.2e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg172_8"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-17, bitscore:
                     51.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIQDDLQAFLAEWHDPSPFLEVQTSGSTGTPKRMRVRKDRMLNS
                     ARLTCDYLGLKKGDKALLCMPLRYIAGKMMVVRSLYAGLDLEVREPSGHPLADWGDTPL
                     RFAAMIPLQVYNTLRVPEERKRLEQTDILIIGGGAIDAALEQEIRQMPNTVYSTYGMTE
                     TLSHVALRRLNGPEASPYYHPFSSVTLSLSPDNTLVIDAPLVCDERLVTNDVARLLPDG
                     SFAIIGRKDNIINSGGIKIQIEEVEERLRPYIMGDFAITSVPDEKLGEAVTLLTEVTNA
                     TGSLLPTQPEACCQGNRKPAVKRTDSLLSRELMGCLPKYQRPRFVLKVEAIPKTGSGKI
                     DRAACRELARNIITKTL"
     CDS             10131..12047
                     /locus_tag="ctg172_9"
                     /transl_table=11
                     /translation="MKRILTITAVSLLALSPMYGQEAYAGYDCVTLLDSTAVTVQPTGS
                     GAFAVCKAFKVQTPKGAVANRIIKYDYDPLTAHAEFRYATIYRANGDVINLDVTGACDY
                     AAPARAIYWGARQIMLEVGRLQPGDVVEYEIAKKGFTYALLTAGDDERFIPPMRGQFYD
                     IVPFWATEPTVRKVYRISMPMEKELQFQFYQGECTSSMRYEDGRKVYTFASDDILPFAK
                     EPNMVDLFDAAPKLMMSSTPRWEDKSVWFNKVNEDYGSFTAIPEAQRKVDELIKGKKTE
                     MEKIAVLTHWVADNIRYSGISMGKGEGFTLHNLKMNYTDRCGVCKDIAGTLIAFLRMAG
                     FEAYPAMTMAGSRVESIPADHFNHCVAVVKLASGTYMPLDPTWVPFCRELWSSAEQQQN
                     YLPGVPEGSDLCLTPVSAPENHYVRIHADNRLDEKGTLRGQFTITAEGQSDSNIRRIFT
                     TGWQSDWQNTMEKQLLAVSPNAKLLRVDYGKDPKNYQAAPIKITFSYEIPDYAIIAGDQ
                     MLIKPLVMNNLYNQVKSFLRIDTKPENRAYGFKDACSRLVEQDETIRLPKGYTLLNAPK
                     NDALRSNAADFEGSLSQEGDRNIVLRQKLALKKRVYDAADWKGFRSAVNAYKSYGDYLI
                     IKK"
     CDS             12061..13083
                     /locus_tag="ctg172_10"
                     /transl_table=11
                     /translation="MIKITYKLILLLSLLAMTVTSFAASEAEYGKVSKAWTLHADGSQE
                     YRSSMELTLFTHTAMNSTYGESFIVYNPDFQTLKIHSSYTRQKDGTIVKTPDNAFVEVL
                     PRFAADAPAYNQLKEMVVVHTGLELGATIYLDYSIITKPGYYPALDINERLQETSPVKE
                     CKVSISVPEGTPLACGLYGSPVKAVEESHDGIKEVHWTLRNIPASSREAFQPKNREASP
                     HLVASTYPSGKAALATLDKRLKESQGYESKTFAQFLTDKSGNEQEKVNIIRDHILNNLS
                     TCPIPMAMTGYTVRDIDTVLRSAYGTPLEIAQLLNVMLNAAGIPSEVLAVYPGHLDTDA
                     C"
ORIGIN
        1 ctttttcttt acttaccgca acttgggtac ggaacgataa ttttagtact tttgtcgcct
       61 acttcgggac ctagaacgcc cgggctgtat ttatccgatt aattgaattg ataaaggaat
      121 gggaatttca tcgccgcttg tagatttgca acatcaatat gatctcctgc agaaagaata
      181 tgaatatgag aaggaaacat accgacagca atccgagcgt acgggtttgc gaaaacgagt
      241 ggcgcagggc ctctgttggt atccggtcac tccgggacgc agttatcata actccttaaa
      301 ccaattggtg atcgagatcg aaaggacaga agaccgggag atcgagcata attttgagta
      361 cgggcgcccg gtttgcttct ttacggcaga tatcagtggt aaatttaagt atctggattt
      421 ctccgccacg atcagctacg tgcaagagga ccggatggtg gtagttctcc ccactccttc
      481 cgccttgatg gatatacaag gaaaaagcaa tgatctcggc gtgcaactct acttcgacga
      541 gaccagctat aaaacgatgt tttccgctct ctcggacgtg atgcgggcaa aaaacaacca
      601 actctctcat ctaagggatg tattgctggg acaggaaaaa ccgggacagc gggaattatt
      661 cccgatccgc ttcccttggt tgaaccgttc tcaggaagaa gccgtaaata aggtattggg
      721 agcgaaacaa gtatctatcg tacacggccc tcccggaact gggaaaacaa ccaccttggt
      781 ggaagccatt tacgagaccc ttcaccggga gaatcaagtg atcgtttgcg cccaaagtaa
      841 tatcgccgta gactgcatct cggagaaact ggtagataga ggcattaacg tcctgcgcat
      901 cgggaacccc actcgtatca atgacaagat gctctctttc acatatgaac gccgtttcga
      961 atcgcatccg gattatcccg aattatggag catccggaaa gcgatacggg atatacaatc
     1021 caatatgcga aagaaaagcc gggaggaacg ggatacgatc cgaaaccgcc tctcccgttt
     1081 gaaattccgg gcgaccgaac tggaagtcaa gatcgataca gagctgttcg acgaggctcg
     1141 tgttgtcgct tgcaccttgg ttggctccgc aaaccgggtc atgatgaacc ggcacttcac
     1201 gaccttgttt atcgatgagg ccgcccaagc cttggaagct gcttgctgga tagcgatcgg
     1261 caaggcggac cgggtcatac tagcgggcga tcatcaccaa ttgcccccta ctattaaatg
     1321 tatagaagcg gaacgagaag gcttaggacg taccttgatg caaaagatag cccacacgaa
     1381 accggaaacg gtctctctcc tgaagatcca ataccgtatg cacgaggata tcatgcgctt
     1441 ctcctcccaa tggttctatc ataacgaact cgaatccgct cccgaggtaa gtgggcgagg
     1501 aatcttgcga ttagacactc ccatcgtatg gttcgatacg tccgagtgcg atttcacgga
     1561 aaatacgaga gaggagacca tgagccgtgt caacaggcaa gaggcggaat tgctcgtgga
     1621 acaattacgc tcctatatac agaaaatatc caaggagaga gtgctggagg agaatatcaa
     1681 cttcggattg atctcccctt ataaggcgca ggtacaatac atccgtaaat taatcaaaca
     1741 ggacgctttc ttcaagcctt tacgcagact gattaccgta cataccgtag acggtttcca
     1801 agggcaagaa cgcgatgtca tcttgatcag tttggtaagg gccaacgagg atggaaagat
     1861 cggcttcttg aacgacttac ggcgcatgaa cgttgcgatc acccgtgccc gtatgaaact
     1921 gatgatcttg ggagacgctt ccacccttac ccggcacgca ttttataacg aactctataa
     1981 ttatatctcc caaagaggta aaataatcac gatcaatacg aaacaagagc atgaactata
     2041 aattattggt actggattta gacggtacac tgacaaacag taaaaaagag atcaccccgt
     2101 ttacgaggga aacccttctg caagcgcagg aaaaaggatt gcatctggtc ttagcctccg
     2161 gccggcccac ctacggtatc gtgcctttag ccgaggaact gaacatgaag caatatggtg
     2221 gttttatcct ttccttcaac ggcggtaagg tgatcgactt tatgacagac aaggtacttt
     2281 tcgaacaggc tttgccacca gatatcgtac ctgttttata caaccgctcc aaagaagcgg
     2341 gactggctat cctttcctac aacggtaaat atatcttaag cgagcacccg gaaaataaat
     2401 acgtacaata cgaatcattc ctaacaaaga tgaagatcaa ggctaccgac gattttctgc
     2461 gggatttgca tcagccagcc gataaatgct tggtggtagg cgaaccggag atgttggtat
     2521 cgttggaaga gaagctccgc caagaattag ggaaacgtat caacgtatat cgttccgagg
     2581 cattctatct ggagcttgtc cccaaaggca tcgataaggc agcctcgtta tcccgcttac
     2641 tagagcgaac ccggataaaa caggaggaag tgatcgctat cggcgatggt ttcaacgatg
     2701 tatccatgat ccgtttcgcc ggattgggag tcgctatggc caacgcccag ccccctgtca
     2761 aggccaatgc cgaccgcatc acccaataca cgaacgatga ggatggagtg gctcgtttca
     2821 tccaagaatt gctttgaaaa aaaacacgta cgtattttcc gaaaaacatg tacatgtttt
     2881 cgcgagaaca cgtacgtgtt ttttcagaga catttacacc agtatcgaca caggccaatg
     2941 cctataccgg catacgccta taccagtagt gccgtagggc tacgccagta taggcgtgag
     3001 cttgcgccga tatacgtaaa ttcctttcat ggaaatgtct tctaactatc aactatttta
     3061 tgtatatttg tattctaaac cataaaaata agacgccatg aagtacaaat tattagtctt
     3121 agacgtagat gggacgttgc ttaacgacaa gaaagagata actccccgga cccatgccgc
     3181 cttgttaaag gctcagcaga tgggagttca tgttgtattg gcatccggcc gacccaccaa
     3241 cggggttcaa cccttggcgg aggcccttga attgaatcat tacggtggtt tcatattatc
     3301 ttataacgga ggtcagatca tcaatgccca gaccggagaa ttgatgttcg agaaacgaat
     3361 cgatccggcc atgattcctt atttgaaccg gaaggcgaag gaaaacggtt tcgcgatctt
     3421 cacatatcac aaggactata tcctaaccga tagcccggaa aacaagcatg tccaagagga
     3481 ggccgaactc aataagatgc gcatcatcgg tgtggagaat ttcccggaag cggtggattt
     3541 cgcaccctgt aagtgtattc ttaccagcga tgacgagaac aatctagtgg gtctcgaaaa
     3601 tcattggaag aaacgtctgg acggggtatt ggaagctttc cgctccgagg actatttctt
     3661 ggaggtagct cctcatttca tcaataaggg aaatacgttg gcggtattga tggagatgct
     3721 gaatatcacg accgaagagg ttgtcgctat cggtgatggc gtggccgacg tatccatgct
     3781 tcaattagcc ggtaccggcg tggcgatggg taacgcacgc gattccgtaa aggcttgtgc
     3841 cgatttcacg accttaccca ataatatgga aggtgtggcg gtagcgatcg agaaagcgat
     3901 ccttgccacg atcaaaccca cagaggttcc gttagatcaa ctaaacgcac gggccaaaca
     3961 tgctttaata ggtaatctag gcattcaata tacctatgcg tcagaggatc gtgtggaagc
     4021 gaccatgcct gtagacgaac ggacccgcca gcctttcggt atcttgcacg gaggcgctac
     4081 gctggctttg gcagagaccg tggccggact aggttccatg attctggcga aaccggacga
     4141 gatggtagtc ggcatgcaag ttagcggcag ccatatgtcg tccgcccacg agggagacac
     4201 ggtacgtgcc gtcgggacga ttatccacaa aggccgttca tcccatgtgt ggaacgtaga
     4261 catattcacc tctaccgaca aactggtttc ctcggtacgg gtaatcaata gcatactaaa
     4321 gaagaaatga ttccaagaga tttttacgaa ataatagaca cgttgatcaa gcaaggccgg
     4381 agtttcgcta tttggcgtat tcccggtgag gataggctcc atttcaggat gcaaagcgcc
     4441 ggctctcctt gcctattata cgacataaaa gacttaaatg aacggagcgg ttttgtaatc
     4501 gctccgtttc aggtgacagc ggaacgacct atcgttttaa tccaaccgga ttgctttgaa
     4561 atcccctccg aatccgatag ggatttctct cgagagaaaa acgaattccc ttcgaatgaa
     4621 atcgaaatcc cgtccgaatc cgaggagaag gaacgatacg cttaccattt ctccctgttt
     4681 accaaccctt tgctaaaagg aagccaagat aaactagtcc tatcccgtag caaaacgatc
     4741 cggaaagatc cctctttctc acccggcaag gcattcttcg ccgcagtaga acgatatatc
     4801 cgctcctatg tctacctttg ccataccccg gaaaccggaa cttggatggg tgggacaccg
     4861 gaaatcttgt tatccggcga gaaaggcgac tggcagacgg tagccttggc cggaacccaa
     4921 tccttacgag acgggaaatt accgaaaagc tgggaccata agaattggag agaacagcaa
     4981 ttagtcgcct cctatatacg ccgccagctg tctaccttgg ggattactcc cgaggagaag
     5041 gggccttatt cagcccgggc cggagaggtt tcccatttga aaagcgattt cttcttctcc
     5101 ttgccggatt ccgagaagtt gggtgacgtg cttcaactat tgcaccctac tcccgccgtt
     5161 tgcggtcttc ccaaggagga agcttatcac ttcatcatcg agcatgaggg gtacgatcgt
     5221 agctattact ccggtttcat cggttggctg gatcccaaag gcaaaacaga tctgtacgta
     5281 aatctccgtt gcatgaatat cctccccaaa acctttacgc tgtatgccgg aggcggtctg
     5341 ttggcggcct cgcagctaga ggatgagtgg caggagacag aggataaatt agatacgatg
     5401 cggagaatag tgggtaattt ataattttat atcatataat gtatagcgat aaaaagaaca
     5461 tccttcaatt ggtagccttg ctgatagagc acggcgtaag taatatcgtg ctatgtccgg
     5521 ggagccggaa ctctccgatt gtgcacacat tggcaaacca ttcgttcttc aattgccatt
     5581 ccgtgacgga tgagcgaagc gcgggattct tcgccgtagg gctagcgttg cacggtggta
     5641 agccggcggc tgtttgctgt acctcgggca cggccttgct gaatatacat ccggcggtag
     5701 cggaggcttt ctatcagaaa gttccgcttg tcgtgatatc cgccgaccgc cccgccgcat
     5761 ggatcgggca aatggacgga cagaccttgc cgcaacccgg ggtgttcggc tcgctggtaa
     5821 agaagtcggt gcagctaccg gaaatacata cggatcaaga tgaatggtat tgcaatcgat
     5881 tgatcaacga ggcgttgttg gaactgaacc atcacggcaa aggaccggtg catatcaacg
     5941 ttccgatctc cgagccttta tttcagttca cgacacccga attgccgaag gtacgggtaa
     6001 tcacccgtta tcaaggcttg aacgtgtacg accggaaata tgatgacctg atcgagcgct
     6061 tgaacaaata tagcaagcgg atgatgatag cgggacaaat gagcttgatc tatctcttcg
     6121 agaagaaaat atgcaagtta ctatacaagc atttcacttg gctctccgag cacatcggca
     6181 accgtatcgt accgggatta ccgatcaaga atttcgacgc tatcctgtac gctaccccgg
     6241 aggaggaaaa agagaagcta gttcccgagc tcgtaatcac ctacggcggc catattgtct
     6301 ccaagcggct gaaagagttt ttgcggaaac acccgcctaa ggagcattgg catgtctcac
     6361 tggatggaga ggtagcggat ttattcggta gcctgaccac ggtgatcgag atggaccctt
     6421 tcgagtttct ggagaaaatc gcttatatgc tggagaatag gcagattgaa tatccgaagg
     6481 cttgggaata taaatcccgg aatctgccgg agccggagtt cgcttactcc gaaatggcgg
     6541 cgatcggtgg tttgatacgt tcgcttccgg ctgaatcggc cttgcatctg gggaatagct
     6601 ccaccgtacg ttacgcacaa ttgtacaccg tacccgagac ggttgaggtt tgttgtaacc
     6661 gaggtacgag cgggatcgaa ggctccttgt ctacggctat cggatacgcc tcggcctcgc
     6721 aaaaactaaa ctttatcgtt ataggcgatc ttagtttctt ctatgatatg aatgcgttgt
     6781 ggaacggaaa cttgcacaat aaccttcgta tcctgctctt gaacaacgga ggtggtgaga
     6841 tcttccaagc cttgccagga ttcaagatga acgagcgtac gcaccgttac gtcaccgcct
     6901 cccaccagac ctcagcggag ggatgggcca cggaaagggg attctcctac tccgccgttc
     6961 ataacgccga ggagttggca gctgcgatga gcgcctttac ccaaacggag caaccgagcg
     7021 aacatcccct attcatggag gttttcacgg acaaagcgga agacgtacga ttgctcaagg
     7081 aatattatca tcaactaaaa aattcatccc aagcacaaaa catataatat atggaaacga
     7141 aaagagaatg gacaaccatc aaggaatacg aggagatctt atttgatttc tacaacggca
     7201 tcgcccgcat tacgataaac cgggaacggt atcgcaacgc ttttaccccg actacgacca
     7261 cggagatgag cgacgccttt tacatctgcc gggaacgtcc ggacattaac gtagtcgttc
     7321 tgacaggagc cggagatacg gcgttttgcg cgggaggcga tatgaacgtg aaaggacgtg
     7381 gcggctacgt gggtaaagac ggcgtacctc gcttgaacgt attggacgta caaaagcaga
     7441 tccgctctct cccgaaaccc gtcatcgcgg ccgtgaacgg tttcgctatc ggcggcggac
     7501 acgtattgca cgtggtttgc gaccttacga tcgcttccga gaacgctatc ttcggacaga
     7561 caggccctcg tgtgggtagc ttcgacgccg ggttcggctc ttcttacctc gcccgtgtgg
     7621 tcggacagaa aaaggcccgt gagatctggt tcctatgccg caagtacaat gcacaggagg
     7681 ctttggatat gggtctggta aataaggtag tccccttgga taaattagag gacgagtacg
     7741 ttcaatgggc cgaggagatg atgttgctta gcccgttggc cttgcgcatg atcaaggcgg
     7801 gcttgaacgc cgagttggac ggacaggccg gtatacaaga gttggccgga gacgctacca
     7861 tgctttacta tatgacggac gaggcgcagg aaggcggcaa ggcattcttg gagaaacgcc
     7921 gtccacgctt cgaggattac ccgaagttcc cgtaaaggga attgagaatt gagaattgaa
     7981 aattgagaat gaatggtgaa ggagaggttt tataaaacag aggtggttcc ccggtgcttg
     8041 actttcaagc gaccggcagg aacctcacgg ggtgtttaca cgacccggaa attgtgggag
     8101 gtccgaatcc gcaaggaaga cgaaccctcg gttattggta tcggagaatg tgcccccctg
     8161 ccggatctca gttgcgatta tggagtggat tacgagatca cgttatccaa ggcttgcctc
     8221 gatctggaac agaagggata tgttgacacc gaatctttgc gccattaccc atccatcctt
     8281 ttcggattgg aaatggccat gcgtcattat gaacagggtg gttggcggca ttacgacacg
     8341 cccttctcgc gggggcaagc gggcatcccc attaacggac tgatctggat gggcgattat
     8401 aagtacatgc tggaacaggt agaggaaaag atgaaggagg gcttccgctg cgtcaagctg
     8461 aagatcggcg ctatcgattt cgaccgggaa ctctctttat tgaaacacat ccgtgcgcat
     8521 ttctctgcca aggaaataga gcttcgggta gacgccaacg gcgctttcac accctcggag
     8581 gcgatggaca aactgaagcg gctcgccgag atggacttgc attccatcga gcagcctatc
     8641 cgtgccgggc agttggaaga aatggcacac cttgcggcag agtcacccct tcccatcgct
     8701 ctcgacgagg aactgatcgg ctgtaacgcc ccggacgaga aacggcggtt gttggaaacg
     8761 atccatcccc aatacattat attaaagcct tccctccacg gaggcatcgc cggatgtacg
     8821 gaatgggttc acttagcgga aactatctta gggagtaccc ccgagcgacc caaatggtgg
     8881 gtcacctccg ctctggaatc gcaaatcgga ctgaacgcta tcgcccaatg gtgcgccacg
     8941 ttaggtaacc cgctaccgca aggtctggga accggcgaga ttttcaagga tgataaacat
     9001 cggttaatcc aacgaaaagg agacaccatc tggttctcca acgacctttg acctatgccg
     9061 atacaagatg atttacaagc attcttagct gaatggcacg atccctcccc ttttctggaa
     9121 gtccagacct ccggctccac cggtacgccc aagcggatga gagtgcgcaa ggaccggatg
     9181 ctgaacagcg cccggcttac ctgcgattat ctgggtctta agaagggcga caaggccctg
     9241 ttatgtatgc ccctgcgcta tatagccgga aagatgatgg tggtccgctc cctatacgcc
     9301 ggactggatc tggaggtgcg tgagccctcc ggacacccgt tggcggattg gggggatacg
     9361 cccctgcgct ttgccgccat gatccccttg caggtttaca atacgttgcg agtacccgag
     9421 gaacgtaaac ggctggagca aacggatatc ctgattatcg gcggcggggc gatcgacgcg
     9481 gccttggaac aggagatacg gcagatgcca aacacggttt attccaccta cggaatgacg
     9541 gagacgctgt ctcacgtcgc cctgcgccgg ctgaacgggc cggaagcctc gccctattac
     9601 catcccttct cctcggtgac gttatccttg tcgccggaca ataccttggt gatagacgcc
     9661 ccattggttt gcgacgagcg gctggtgacg aacgatgtcg cccgcctgct gccggacggg
     9721 agtttcgcca ttatcggaag gaaagataat atcatcaata gcggaggtat caagatacag
     9781 atcgaggagg tggaagagcg gctacggccc tacataatgg gcgatttcgc catcacctcc
     9841 gtaccggacg agaagttggg cgaggcagta acgttgctca ccgaagttac caacgcaacc
     9901 ggaagcctgc tgccaacgca accggaagcc tgctgtcaag gcaatcggaa gcctgctgtc
     9961 aagagaactg acagcctgct gtcaagagag ctgatgggat gcctccccaa ataccaacgc
    10021 ccgagattcg tcttgaaggt agaggccatc cccaaaaccg gaagcggcaa gatcgatcgt
    10081 gccgcctgcc gggagctagc gagaaatatc atcacaaaaa cactataaac atgaaaagga
    10141 ttctaacaat caccgcggtc tccctattgg ccttatcgcc tatgtacggg caggaagcct
    10201 acgcgggata cgactgcgtc accttgctgg acagcaccgc cgtcacggta caacctaccg
    10261 gctcgggggc tttcgccgta tgcaaggctt ttaaggtaca gactcccaag ggagccgtcg
    10321 ccaaccgtat catcaaatac gattacgacc cgctgacggc gcatgccgag tttcgttacg
    10381 ccacgatcta ccgtgcgaat ggcgacgtga tcaatctcga cgtgactggg gcttgcgact
    10441 atgccgcccc cgcacgtgcc atctactggg gcgcccggca gatcatgctg gaagtgggcc
    10501 gcctgcaacc gggagatgtc gtggagtacg agatcgccaa gaaaggtttc acctacgcct
    10561 tgctgacggc gggcgacgac gagcgtttca tccctcctat gcggggacag ttttacgata
    10621 tcgtcccctt ctgggctacc gagcctaccg tgcgtaaggt ataccggata tccatgccga
    10681 tggagaaaga gttgcaattc cagttctacc aaggcgaatg tacctcttcc atgcgatatg
    10741 aggatggacg gaaagtatat accttcgcct ccgacgatat ccttcctttc gccaaggaac
    10801 cgaatatggt agacctattc gacgcagccc cgaagctcat gatgtccagc acgccccgct
    10861 gggaagataa atccgtatgg ttcaataagg ttaacgagga ttacggaagc tttaccgcga
    10921 tcccggaagc ccaaaggaag gtagacgagc tgatcaaagg caagaagacg gaaatggaga
    10981 agatagccgt gctgacccac tgggtggccg ataacatccg ttactccggg atctcgatgg
    11041 gtaaaggcga gggtttcacg cttcacaacc taaagatgaa ttataccgat cgttgcggtg
    11101 tctgcaagga tatcgccggt acgttgatcg ccttcctccg catggccgga ttcgaggctt
    11161 acccggcgat gaccatggcg ggaagccgtg tagaaagcat ccccgccgac catttcaacc
    11221 attgcgtggc ggtggtaaaa ctggctagcg gcacgtatat gcctctcgac ccgacttggg
    11281 ttcctttctg ccgggaatta tggagtagcg ccgagcaaca gcagaactac ctcccgggtg
    11341 tgcccgaagg ctccgacctc tgcctgaccc ctgtctccgc cccagaaaac cactacgtcc
    11401 gcatccacgc tgacaaccgc ctagacgaga aaggcacgct ccgcggacaa ttcacgatca
    11461 ccgccgaggg acagtccgac agcaatatcc gccgcatctt caccaccgga tggcaatccg
    11521 actggcagaa cacgatggag aagcaattgc tggccgtatc ccccaacgcc aaactgcttc
    11581 gtgtagatta cggtaaggac ccgaagaact atcaagcggc ccctatcaag atcacgttct
    11641 cttatgagat ccccgattat gcgatcatcg ccggagacca gatgcttatc aagccgctag
    11701 tcatgaataa cctctacaat caagtgaaga gtttcttgcg tatcgatacg aaaccggaaa
    11761 accgtgcgta tggattcaag gacgcttgct cccgtttggt agaacaagat gagaccatcc
    11821 gtctccccaa aggctatacc ctcctgaacg ccccgaagaa tgacgccctg cgaagcaatg
    11881 cggccgattt cgaaggttcc ctttcacagg aaggcgaccg gaacatcgtc ttgcgccaga
    11941 agctagcgtt gaagaagcgt gtctacgacg cggctgactg gaaaggcttc cgttccgccg
    12001 tgaacgccta taagagttat ggtgactatt tgattatcaa gaaataaaaa aagaaagaca
    12061 atgattaaga taacctataa actgattctt ctcctaagct tgttagcgat gacggttact
    12121 tcattcgccg catcggaggc tgagtacggg aaagtatcga aagcttggac cttgcatgcc
    12181 gacggcagcc aagaatatcg atcctccatg gagttgacgc tcttcacgca taccgcgatg
    12241 aatagcacgt atggcgagag ttttatcgtc tacaatcccg atttccaaac actgaagatt
    12301 cactcatcct atacgaggca gaaagacggt acgatcgtaa agacacccga taacgccttc
    12361 gtggaggtcc tgccccgttt cgccgccgac gctccggcct ataaccaact caaggaaatg
    12421 gtcgtggtac acactggcct agaacttggg gccacgattt acttggatta ctctattatc
    12481 acaaaaccgg gctactatcc ggctctggat atcaacgagc gactacaaga gacctctccc
    12541 gtgaaggaat gcaaggtctc tatttccgta ccggaaggga cccccttggc ttgcggtcta
    12601 tacggctccc ccgtaaaagc cgtggaagag agccatgacg gtataaagga ggtacactgg
    12661 acactacgga acattcccgc ttcctcccgt gaggctttcc aaccaaagaa ccgtgaggct
    12721 tcaccccact tggtagcctc tacctatcct tcaggtaaag cggccttagc cactttggat
    12781 aagcgcttaa aggaatcgca gggatacgag agcaaaacct tcgcccaatt cctcaccgat
    12841 aaaagcggta acgaacaaga gaaggtgaac atcatccgag accatatact caacaatctc
    12901 agtacctgtc ctatccccat ggcgatgacc ggctataccg tccgtgacat cgataccgtt
    12961 ctccgcagtg cttacggtac gccgctagag atcgcacagc tcttgaacgt gatgttgaat
    13021 gccgccggaa tcccgtcgga agtcctcgcc gtctatcccg gccatctcga tacggacgct
    13081 tgcgg
//
