LOCUS       gnlProkkaPPNDKLOK_363  10485 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPNDKLOK_363.
ACCESSION   gnlProkkaPPNDKLOK_363
VERSION     gnlProkkaPPNDKLOK_363
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 00:45:27
            Original ID  :: gnl|Prokka|PPNDKLOK_363
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10485
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..324
                     /locus_tag="ctg358_1"
                     /transl_table=11
                     /translation="MVMNNACYAVWKKWQNAPEGYSPEIMVTLEKLDKRIVLSIRDNGE
                     GMGPEVKRKLFDSFFTTKPVGQGTGLGMAIVRDIIENKHHGKVLFDSVLHEYTCFRFII
                     PIA"
     protocluster    1..10485
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2699:5129]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2700..5129
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..10485
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10485
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             321..2687
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 167; E-value: 1.6e-50)"
                     /gene_kind="transport"
                     /locus_tag="ctg358_2"
                     /transl_table=11
                     /translation="MKRCLLYILCCFGVVQLSAQPADNIRNSFVKAETFYKSGDIDEAC
                     RILEENLSSFQGTMHTEACRLAALCCLALDRFPEAEKYVSLLLKDEPYYYISLQDPERF
                     ADMVRKHRETKVTLVTASQQVETPEEAPVPVTLITEEMIRAIHARCLRDVLIAYVPGIS
                     GLSSNEEMNLAMRGVYSPEQENILIMQDGQRLNSYITNAVSPDYGISLAKVKQIEVLRG
                     PASSLYGSVALTAVINIVTKDGVDVRNGSISVSAGNRGQLAADLLLGKHDMNMDFMAWF
                     SLYRATGESVFVPAEKQYALYPRDGFIRLDNYSGFPAMDGGIKLQRGNLLFSFSMNYAK
                     KRQPYSMWLFSSPYSYERFRTFDGSGPGYSRWSAREQAVYSRTWQRITFSTAFYTDWNK
                     NVHYETSGDTLQDYPIFPNYDYQPIIYPTRGAFQYIRWMDFNVGFNGRVNYAYDWGKLG
                     KGNMLGGVEWNRYTLYDSEYLEGMNFKEIVRTWIEKRLYTGHEMNTDAFFQIKHNLHKN
                     WIVNAGIRYDYKRRSNKRTLQAFSPRLSLIYLRNGLNIKASYSRAFVDAPYYYRNNEMD
                     TYSGGENLQAEYLSSYQVTCAYHHSPSHIDVECNLFYNRASHFLFTQPETRVYENAGSL
                     DMGGVEVVARYKADRLSLDGNLCFQKVLNYTNFFVTDGSVNNVPGFSMNLVANYFLLKK
                     KVQSWSAHLKLNCSSHCYTQVSVLEDGLNGDATNYTVRLPGYAVFSFTTRYKYKRIEGS
                     LGIENLFNNRYECGGATVPIRQKGRWISASILYNF"
     CDS             2700..5129
                     /NRPS_PKS="Domain: AMP-binding (12-401). E-value: 1.8e-83.
                     Score: 272.2. Matches aSDomain:
                     nrpspksdomains_ctg358_3_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (509-568). E-value: 2.7e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_ctg358_3_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     260.1; E-value: 5.3e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg358_3"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-88, bitscore:
                     285.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.9e-11, bitscore:
                     32.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNIQENLSRSLSTWGDKPAVVAKDGTVSYQMLERYSANIAQSI
                     RQRLSVTDPSGLRNICIGVCMERNKTLVPAILAIFRLGATYLPIDPSLPDNRKRYMAEN
                     ADMVLLLTDSSNEVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPDDCAYIIYTSGTTGNP
                     KGVRISYRNLDTFTRNLVDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLIL
                     AGEDERRDISLLDELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNR
                     LKQQPYRLMNVYGPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGAT
                     GELCLGGPQVSLGYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVK
                     IRGFRIELTEIAERLNRDPDVERAHVVVVERNGRQLLGAYLQPSVSGNFHPEEVKERLR
                     AELPYYMIPNLWQVVDHFQRTINDKIDVRALPAFTSLELKYVPPVHPGEVILCGILKEM
                     LGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPINVSAVYTARNLRRLLLVPRQEP
                     IYWYRQQNLKKPVIILVCGSAYFNHLYFNLADRLYPKYDFLVVDAIYDHFNKVATDIPE
                     LLEYYVRTVQPMIRERTVYALTGFCMGAELAVGLAEMLHRSMGIMPKVFALDGQAWQNP
                     ALCQNYPLLVFPGDTDEMVRERNEIINIYFRTTPNLIYQGEVIVLLSGLFHQQAGLSPE
                     ESWTEENYRIFRTEYDNCERLWNKYYPNAPVLRLPADHWHFLEGESLEQLITVFLK"
     aSDomain        2736..3902
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg358_3_AMP-binding.1"
                     /evalue="1.80E-83"
                     /label="ctg358_3_AMP-binding.1"
                     /locus_tag="ctg358_3"
                     /protein_end="401"
                     /protein_start="12"
                     /score="272.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LSTWGDKPAVVAKDGTVSYQMLERYSANIAQSIRQRLSVTDPSGL
                     RNICIGVCMERNKTLVPAILAIFRLGATYLPIDPSLPDNRKRYMAENADMVLLLTDSSN
                     EVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPDDCAYIIYTSGTTGNPKGVRISYRNLDT
                     FTRNLVDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLILAGEDERRDISLL
                     DELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNRLKQQPYRLMNVY
                     GPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGATGELCLGGPQVSL
                     GYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVKIR"
     aSModule        2736..4403
                     /complete
                     /domains="nrpspksdomains_ctg358_3_AMP-binding.1"
                     /domains="nrpspksdomains_ctg358_3_PP-binding.1"
                     /locus_tags="ctg358_3"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2928..2969
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg358_3_0001"
                     /evalue="3.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg358_3"
                     /protein_end="90"
                     /protein_start="76"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LAIFRLGATYLPID"
     CDS_motif       3150..3206
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg358_3_0002"
                     /evalue="1.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg358_3"
                     /protein_end="169"
                     /protein_start="150"
                     /score="26.8"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGNPKGVRIS"
     CDS_motif       3708..3794
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg358_3_0003"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg358_3"
                     /protein_end="365"
                     /protein_start="336"
                     /score="27.3"
                     /tool="antismash"
                     /translation="LGATGELCLGGPQVSLGYIGSVQLNEKSF"
     CDS_motif       3867..3929
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg358_3_0004"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg358_3"
                     /protein_end="410"
                     /protein_start="389"
                     /score="36.2"
                     /tool="antismash"
                     /translation="FIGRKDTQVKIRGFRIELTEI"
     aSDomain        4227..4403
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg358_3_PP-binding.1"
                     /evalue="2.70E-10"
                     /label="ctg358_3_PP-binding.1"
                     /locus_tag="ctg358_3"
                     /protein_end="568"
                     /protein_start="509"
                     /score="32.6"
                     /tool="antismash"
                     /translation="LCGILKEMLGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPI
                     NVSAVYTARNLRRL"
     CDS             5134..9033
                     /gene_functions="transport (smcogs)
                     SMCOG1049:AcrB/AcrD/AcrF family protein (Score: 973;
                     E-value: 2.8e-294)"
                     /gene_kind="transport"
                     /locus_tag="ctg358_4"
                     /transl_table=11
                     /translation="MQTENFTLGKKELLILLGLILVLPFPINWALIELNPLTLMAGADD
                     VPTWIGFGGSYIGGIIGGVISIMILNKTLQQTGVLHHDLKLLQLDTIIYTQQQDWFTGF
                     KQELAENLKSIDLYVLNTVVSSISMKNYAYAKEVLTEINKGLEYQMVAASFSFTSTHLS
                     SEEKKYMSLVRRVQTEYSSFIKDILYYIPLAETISSRKKLNYDQLMDYTLSQYDYLQGQ
                     EGESTASGAIIPRVMEIDPSDDIRKELERIMEERLTGRTYLYHLKSDLAEATHQLIMIG
                     ALLLIIAGTYTAVNMEVDVFPDLNAPTVVVMTEAKGMAPEEVERLVTFPVETAVNGATD
                     VRRVRSSSTTGFSIVWVEFNWGTDIYRARQIVSEKLAVLGDALPSNVGKPTLGPQSSIL
                     GELLIIGLTSDSVSLQDLRTMADWTIRPRLLSTGGVAQVTVLGGDIKEYQILLDPGKMK
                     HYGIGLNEVIDVVKDMNQNAAGGVLYEFGNEFIVRGVLSTNKVEALRKAVIKNVDEVPI
                     TLENIAEVKIGAKAPKMGLASERGKAGILLTVTKQPNTSTLDLTGKLDKSLEDLQKVLP
                     KDVKVTTDIFRQSRFINNSIDNVQKSLYEGGIFVIIVLLLFLMNIRTTVISLITIPLSV
                     IVAILTLKTLGLTINTMSLGGIAIAIGSLVDDAIVDVENVFKRLRENRQKPKEEQKNVL
                     TVVFEASKEVRMPILNSTLIIVASFVPLFFLSGMEGRMLAPLGITFVISLFASTVVALT
                     LTPVLCSYLLNKPKNNGEEHDPYLVRKLKSGYGMALRWTLCHKKVVLGAIGAILIVSLV
                     MMASFGRSFLPPFNEGSFTVSISTLPGISLEESDKIGRMAEDILLSVPEVQTVGRKTGR
                     AELDEHALGVNTSEIEAPFILDKRSKDEVLTEIREKIKVIPGVNIEIGAPITHRINAML
                     SGSRANIAIKLFGTDLNRMYEIGNQIKNSIQDIEGVADLNVEQQVERPQLKIEPKREML
                     AKYGVTLPQFGDIVNVMLGGEAVSQVYEENRSFDLTLKVNDASRASAERIRKLIVDANG
                     RKVPLENIANVTSSMGPNTISRENVARKIVISANVAGRDLRGVVNDIQSKVDSEIQLPE
                     GYHIEYGGQFESEQAASRIITITSIFSILVIFLLLFKEFKSATQSLVILLNLPLALIGG
                     VFSIYFTSGILSIPAIIGFISLFGIATRNGMLLIDRYNSLRASGMSVNDSILHGSLDRL
                     NPILMTALSSGLALIPLALGGELPGNEIQSPMAKVILGGLLSSTILNGFIIPIIYLYIS
                     RKQEKKIETIELTED"
     CDS             9035..10210
                     /gene_functions="transport (smcogs) SMCOG1076:RND efflux
                     system, outer membrane lipoprotein, (Score: 54.6; E-value:
                     1.2e-16)"
                     /gene_kind="transport"
                     /locus_tag="ctg358_5"
                     /transl_table=11
                     /translation="MRTIILIMVLLASVSLVAQENIDSILFSIEENNSTLKALREETNA
                     QKLGNKTGIYLSDPDVEFGYLWGNPGKIGNRQDFSIKQTFDIPTLTGMRSRLAGNQNKL
                     VELQYASERINLLLEAKQYCIDLVYYNGLKKELKVRLRHAQAIADAYRQRLDRGDASIL
                     EYNKVQLNLSTVQGEMSRIEVERNALLSELKRLNGGMDVIFEASNYSPASLPANFEDWY
                     LSAQQKNPLLQYVKQQIEVSKEQVKLGKAMILPKFSAGYSLERTLGQKYQGISVGISIP
                     LWENKNRVKQAKAGVVAAQAREQDSKQQFYDRLRNLYMRASGLQQTAIAYRESLKALNN
                     TALLMKALDVGEISLLNYIVEIGLYYDTVNQTLAAERDFEKALADLSAVEL"
     CDS             10222..10458
                     /locus_tag="ctg358_6"
                     /transl_table=11
                     /translation="MRKLKKPYSQNWRGLSAKWLFILSTVLGIIAGTCFWIFISRCGNE
                     ECFLNYDPLPEMFIGGVIGAFLYVIIWGMTSDM"
ORIGIN
        1 aatgtgatga ataatgcctg ctatgcagta tggaaaaaat ggcagaatgc tcccgaagga
       61 tattcccccg agataatggt gaccttagaa aagttggata aaagaattgt actttctatt
      121 cgtgataacg gagagggcat gggtccggag gtcaaacgaa aactatttga ctcttttttc
      181 acaacaaaac cggtggggca ggggacaggc cttggtatgg caatcgttcg tgatattata
      241 gaaaacaaac accatggaaa agtattgttt gattcggtcc tgcatgaata tacttgtttc
      301 cggtttatca ttcctatcgc atgaaacgct gtctgctata tatcctttgc tgctttgggg
      361 ttgtgcaact gtcagctcag ccggcggata acatccgtaa ttcgtttgta aaggcggaaa
      421 cattttataa gagcggagat atcgatgaag cttgtcgtat cttggaggag aatctgtcgt
      481 cttttcaagg tacgatgcat accgaggcgt gccgtttggc tgcattatgc tgtttagctt
      541 tagaccgctt cccggaagcg gaaaagtatg tttcgctgtt attgaaagac gaaccttatt
      601 attatatctc gcttcaagat ccggaacgct ttgcggatat ggtaaggaaa cacagggaga
      661 ctaaagtaac tctggtcaca gcctcacaac aggtagagac cccggaagaa gctccggtgc
      721 ctgttacttt aattacggag gagatgatac gggctatcca tgcccggtgc ctgcgggatg
      781 tactgatagc ttatgtgccc ggtatatccg gtttgtcttc caatgaagag atgaatctgg
      841 ctatgcgcgg ggtatattct cccgaacagg agaacatatt gattatgcag gatggacaac
      901 gtctgaacag ttatattact aatgctgttt cgccggatta tggtattagt ctggcaaaag
      961 tcaaacaaat agaggtgctg cgcggaccgg cttcttcgct ttatggcagt gtggctttga
     1021 cagccgtgat taatatagtt actaaagacg gggtggatgt tcgtaatggt tccatatctg
     1081 tcagcgccgg taatcggggc cagttggctg ctgacctgct attgggaaag cacgacatga
     1141 acatggactt tatggcatgg ttctccttgt accgtgcaac gggagaatcg gtttttgtcc
     1201 cggccgaaaa acaatatgct ctttacccca gggacggatt catccgtctg gacaattatt
     1261 cgggatttcc tgccatggat ggaggaatta aattgcaacg tggaaatttg ctttttagtt
     1321 tcagtatgaa ttacgcgaag aaaaggcaac cttatagcat gtggctcttt tcttctccat
     1381 attcttatga gcggtttcgt acttttgacg gttccggccc gggatattcc aggtggtcgg
     1441 caagagaaca ggctgtttat agccgcacgt ggcagcggat cactttcagt accgcatttt
     1501 ataccgattg gaataaaaac gtacattatg aaacctcggg agatacttta caagactatc
     1561 ctatttttcc taactatgat tatcaaccta ttatttatcc gactcgcgga gcatttcaat
     1621 acatccgctg gatggatttt aacgtaggct ttaatgggcg tgtaaactat gcctatgatt
     1681 gggggaagct ggggaaaggc aatatgcttg gcggtgtgga atggaatcgg tatacgcttt
     1741 atgattccga gtatttggaa ggtatgaatt ttaaagagat cgtcaggacg tggatcgaaa
     1801 aacgacttta cacgggacac gagatgaaca cggatgcctt tttccagatt aaacacaacc
     1861 tgcataaaaa ttggattgtc aatgccggca tcaggtatga ctataaacgg cgaagtaata
     1921 agcggacatt acaggctttt tctccccgtc tgtcactaat ttatctcagg aacggattaa
     1981 atatcaaagc cagttattcc agagcatttg tcgatgcgcc ctattattac agaaacaatg
     2041 aaatggatac ctattcgggt ggcgaaaatc tgcaagctga atatctaagt tcatatcagg
     2101 taacttgtgc ttatcatcat tcaccttcac atatagatgt agagtgtaat ttattttata
     2161 atcgggcgtc ccatttcctg ttcacacagc cggaaacacg tgtttatgaa aatgccggtt
     2221 ctctggatat gggaggtgtc gaggttgttg ctcgttataa ggcagaccga ctgagcctgg
     2281 atggaaacct gtgttttcag aaagtattga attataccaa tttttttgtt accgatggat
     2341 ctgtgaataa cgtacccggc ttttctatga atcttgtagc aaactacttt ttacttaaaa
     2401 agaaagtaca gagctggtct gcccatttaa aattgaattg cagtagccac tgctacactc
     2461 aggtaagtgt attggaagat ggactcaatg gagatgcgac gaattacaca gtccgtttgc
     2521 ccggttatgc tgtcttttct ttcactacca gatataagta taaaaggata gaaggcagtc
     2581 tgggcattga gaatcttttc aataaccgat atgaatgcgg aggagcgact gttcctatcc
     2641 gccagaaagg aaggtggatt tccgccagta tattgtataa tttctaaatc aaactaataa
     2701 tgaaaacaaa cattcaagaa aatctttctc gatcactctc tacctggggt gacaaaccgg
     2761 cggtcgttgc aaaagacggt accgtctctt atcaaatgct ggaacgttac tctgccaata
     2821 tagcacaatc tatccgtcaa cgtttatcgg taactgatcc gtccggactt cggaatatct
     2881 gtatcggagt ttgtatggaa cgaaacaaaa ctttagtacc tgccattctg gctattttcc
     2941 ggttaggggc aacttattta ccgatagatc cctcgctgcc ggataatcgt aaacggtata
     3001 tggctgaaaa tgcggatatg gttttgttgt tgaccgattc atcgaatgaa gtaggtggaa
     3061 ttccgtccgt ccgccaactt tacctgaatg gggagcaact atccgaaccg gttgttggtg
     3121 actatactga agttcttccc gatgattgcg cctatattat atatacttcc ggaacaacag
     3181 gcaatcccaa aggtgtacgt attagttatc ggaatctgga tacatttacg aggaatctgg
     3241 tagataagaa attgtatcat ttgtctgatc cggcaaacag gtatctggcg tttgcgagta
     3301 tcagttttga tgcttccata ttagaactga tgatgtgtat tccggtcgga ggaacattga
     3361 tcctggccgg tgaggacgaa cgcagagata tttctttact agacgaactg atcaggcgcg
     3421 agaaggtgaa tattgctttt ttccctcctt cgttgctggg catgtttgcc gaccttgact
     3481 ttccatcctt taagactctg ctctttggtg cggaggctat tggtgaaaag ttatttaaca
     3541 ggctgaaaca gcagccttac cggttgatga atgtatatgg accgacagag aataccgtac
     3601 tcagtaccat acggattgta ggcaaagata cgtcgtatga cgatattggc tatccgctca
     3661 agggaactgt ctgttatgtt ttgtctgaaa acctccaaca gacaactctt ggggctacag
     3721 gagaactttg cttgggagga cctcaggttt cgctgggata tattgggagt gttcagctga
     3781 atgaaaaatc attcatctcg tacgatggag aacggttgta caggacaggt gacttggtac
     3841 agcagcaacc ggacggttca atacggttta tcgggcgaaa agatactcag gtcaaaatac
     3901 gtggctttcg tatcgaattg actgaaatag cagaacgatt gaatagagat ccggacgtgg
     3961 agagagccca cgtagtagtt gttgagcgga atgggcgtca attattggga gcctatttgc
     4021 aaccctcagt ctccggtaac tttcatccgg aagaggtcaa agagcgtttg cgtgcagaac
     4081 ttccttacta catgataccc aatttatggc aggtggtaga tcattttcag cgtactataa
     4141 atgataaaat tgatgtccgg gcgctcccgg cttttacttc gttggagttg aagtatgttc
     4201 ctcctgttca tccgggggag gttatcttat gtggaatttt gaaggaaatg ttaggtttgc
     4261 ctcaagtcag tgttgaggcc gatttgattg atgatctggg attaacttcg ctggatatgt
     4321 tgaggcttgt taccgaggcc aataaaaaag gatgtcccat caacgtatct gcagtttata
     4381 ctgcccgtaa tctgcgccga ttattgctcg ttccgcggca agaacctatc tattggtaca
     4441 ggcagcaaaa cctgaagaaa cccgtaatca ttctggtttg tggatctgcc tattttaatc
     4501 atttgtactt taatttggcc gaccgccttt atcccaaata tgactttcta gttgtagatg
     4561 ctatctacga tcattttaat aaagtggcca cggatattcc ggaactgttg gaatattatg
     4621 tccggacggt tcagccaatg atccgggagc gtaccgtcta tgcgcttacc ggcttttgta
     4681 tgggagctga actggctgtc ggcctggccg aaatgttaca tcgctccatg gggataatgc
     4741 caaaagtttt tgctctggat ggacaggctt ggcaaaatcc ggctctctgt caaaattatc
     4801 ctttgttggt atttcccgga gatacagatg aaatggtacg tgaacggaac gaaatcataa
     4861 atatttattt tcgaaccact cctaatctga tttatcaggg agaggttatt gttttgctgt
     4921 ccggattgtt ccatcaacag gcgggattgt ctcctgaaga gtcgtggacg gaggaaaact
     4981 atcgtatatt ccggacagaa tatgacaatt gcgaaagatt atggaataaa tattatccga
     5041 acgctcctgt tttgcgattg ccggcagatc attggcactt tttagaaggg gaatcattgg
     5101 aacaattaat aactgtgttt ttgaagtaga tttatgcaga ctgaaaactt cactttaggt
     5161 aagaaagagc ttcttatttt gcttggcttg attcttgtac tgccttttcc aatcaattgg
     5221 gcattaatcg aactgaatcc gttgactctg atggcgggtg cagacgatgt gcccacctgg
     5281 attggtttcg gcggcagtta tattggagga atcatcggag gggtcatctc gattatgatt
     5341 ctgaacaaga cacttcagca gacaggtgta cttcatcacg atttgaaact cctgcagtta
     5401 gataccataa tttatactca gcaacaagat tggtttaccg gtttcaaaca agaactggca
     5461 gagaacctca aatctattga tttgtatgtg ttgaatacgg ttgtttcgtc tatatccatg
     5521 aaaaactatg catatgccaa agaggtgttg acagaaatca ataaagggct cgaatatcag
     5581 atggttgccg catccttttc tttcacttct acgcatttat catccgaaga aaaaaagtat
     5641 atgagtctgg tacgccgcgt acagactgaa tatagctctt ttatcaagga tattctttac
     5701 tatattcctt tggcagaaac gatatcttcc aggaaaaaac taaactatga tcagctgatg
     5761 gactatactt tgtcccaata tgattatttg caaggtcagg aaggggagtc tacagcttcg
     5821 ggagccatca taccgcgtgt tatggaaatc gatccatctg atgatatacg gaaagaacta
     5881 gaacggataa tggaagaaag attaaccggg cgtacctatt tgtatcacct gaagtcagat
     5941 cttgcagagg ctacgcatca attaattatg ataggggctc tattgttgat tattgcggga
     6001 acttatactg ctgtgaatat ggaagtggat gttttcccgg atctgaatgc ccctactgtt
     6061 gttgtgatga cggaggctaa agggatggct cctgaagagg tggagcgtct ggtgactttt
     6121 ccggtagaaa ccgctgtaaa tggtgccact gacgtacgtc gtgtgcgttc ttcttctact
     6181 acaggttttt ctattgtatg ggtcgaattt aattggggta cggatattta tcgtgcccgt
     6241 cagatagtct ccgagaagtt ggctgtgttg ggtgacgcct tgccttccaa tgtgggtaag
     6301 ccaaccttag gtccacagtc ctccattctg ggagagttgc ttattatcgg tttgacctcc
     6361 gatagtgtat ccctacagga tttgcgaacg atggcagact ggactatccg tccccgtttg
     6421 ttgtctactg gcggtgtagc ccaggtaaca gttttagggg gtgatattaa agagtaccag
     6481 atattacttg atccgggtaa gatgaaacat tatggaatcg gcttgaacga ggtcatagac
     6541 gtagtgaaag atatgaatca gaatgccgcc ggtggtgttt tgtatgaatt tggaaatgaa
     6601 tttattgttc gtggcgtatt atccactaat aaggtggagg cccttcgtaa ggctgtaatt
     6661 aagaatgttg atgaagtacc cattacactg gagaatattg ctgaggttaa aatcggtgct
     6721 aaggctccca agatgggact ggcttccgaa cgcggtaaag ccggtatatt gttgactgtc
     6781 accaagcaac ccaacacaag tacccttgat ctgaccggta agttggataa gtctttggag
     6841 gatttgcaaa aggtattacc taaagatgtg aaggttacta ccgatatttt ccgtcaatcc
     6901 cgttttatta ataattcgat tgataatgtt cagaagtctt tatatgaagg cggtatcttt
     6961 gtaattattg tactgctctt attcctgatg aatatacgta ctaccgttat ttcattgatt
     7021 accataccgc tttcggttat tgtagctatt cttactttga agactttggg gcttaccatc
     7081 aatacgatga gtttgggagg tattgccata gctatcggtt ctttagtgga tgatgcaatt
     7141 gtggatgtgg agaatgtatt caaacgcttg cgggagaaca ggcaaaaacc taaagaggaa
     7201 caaaaaaatg ttctgacagt tgtctttgag gcctccaagg aagtacgtat gcctatctta
     7261 aactccactc tgattattgt agccagtttt gttcctcttt tcttcctttc cggaatggaa
     7321 ggcaggatgt tggcaccatt gggcattact ttcgttattt cactttttgc ttccactgtg
     7381 gttgctctga cccttacacc ggttttatgc agttacctgc tgaataaacc aaagaacaat
     7441 ggtgaggaac atgaccctta tttggttcgt aagttgaaat ccggttatgg gatggctttg
     7501 cggtggacgt tatgccataa gaaagtggtt ttgggagcta tcggagccat tttgattgtt
     7561 tcgttggtga tgatggcttc ctttggacgt agttttcttc cacctttcaa tgaaggctcg
     7621 ttcaccgtga gcatcagtac tttgcccggt atttctctgg aagagtctga taagataggc
     7681 cggatggccg aagatatact tctctcggta ccggaggtac agactgtagg acgaaagacc
     7741 ggacgtgctg aactggatga gcatgccttg ggtgtgaaca cttccgaaat agaggcgccg
     7801 tttatactcg acaagcgttc aaaggatgaa gttctgacag aaatccggga gaaaataaag
     7861 gttattccgg gtgtgaatat tgaaattggt gcacctatta cacaccgtat caatgctatg
     7921 ttatccggat cgagagctaa tatcgccata aagttgtttg gtacggactt gaacaggatg
     7981 tatgaaatcg gaaaccagat aaaaaattcg attcaggata ttgaaggtgt agccgacctg
     8041 aatgtggagc agcaggtaga acgtccacag ttaaagatcg agcccaaacg ggagatgttg
     8101 gctaaatatg gcgttacact tcctcagttt ggtgatattg taaatgtcat gctgggaggt
     8161 gaggcagtgt ctcaggtata cgaggaaaat aggtcttttg atttgacgct gaaggtgaat
     8221 gatgccagtc gtgctagtgc cgagagaata cgcaagctga tcgtggacgc caatggtcgt
     8281 aaagtgccgt tggaaaatat tgccaatgtg acatcatcga tggggcctaa tacgattagc
     8341 cgtgagaatg tggctcgtaa gattgttatt tcagccaatg ttgccggtcg tgatttacgg
     8401 ggagtagtaa atgatattca gtcgaaagtt gacagtgaga tacaattacc cgaaggatat
     8461 catattgaat atggcggaca gtttgaaagt gagcaggctg cttcgcgtat tatcactatc
     8521 acttccattt tctctatcct ggttattttc ctgctcttgt tcaaagagtt caagagtgcg
     8581 actcagtcat tggtaatcct gctgaatctg ccacttgcac tgattggagg tgtgttcagt
     8641 atctatttca catccggtat attgagtatc ccggccatta tcgggtttat ttctcttttt
     8701 ggtattgcaa cccgtaacgg tatgctgttg atagacaggt ataacagcct gagagcttcc
     8761 ggaatgtctg tgaatgacag tatcctgcac ggttctctgg accgtctgaa tccgattctg
     8821 atgacagctt tgtcttccgg attggcattg ataccgctgg cattgggagg tgaactgccc
     8881 ggtaatgaaa ttcaaagtcc tatggccaaa gttatcttgg gaggactttt gagttcaact
     8941 atcctcaatg gatttattat tcctattata tacctgtata tcagtcgtaa acaagaaaag
     9001 aaaattgaaa caattgaact aactgaagac taaaatgaga acaattatat taataatggt
     9061 gttgctggca agtgtgtcac ttgtcgccca agaaaacata gacagcatac ttttctccat
     9121 tgaggagaat aattcaaccc tgaaagcatt gagagaagaa acaaacgctc agaaattggg
     9181 gaataagaca ggtatatact tgtccgaccc tgatgtagag tttggttatc tttggggaaa
     9241 tcccggaaag atcggtaatc gccaggattt cagtatcaaa cagacttttg acattccgac
     9301 ccttaccggg atgcgaagtc gcttggccgg caaccagaat aagctggtag aacttcagta
     9361 tgcttctgaa agaattaacc tgcttttgga ggcgaagcaa tattgcattg atctggttta
     9421 ttataacggt ttgaaaaaag aacttaaagt ccggttacga catgcacaag ccatagccga
     9481 tgcttatcga caacgactgg atcgtggaga cgccagtatt ctggagtaca ataaggttca
     9541 gttgaatctt tccaccgtgc aaggggagat gtcaagaata gaagtggaga ggaacgctct
     9601 tctttccgaa ctcaaacgat tgaatggtgg tatggatgtg atttttgagg cgagcaacta
     9661 ttctccggct tcgctgcctg ctaattttga agactggtat ctgtcggctc aacaaaagaa
     9721 tccgctactg caatatgtaa agcaacagat agaggtcagt aaggagcagg taaagctcgg
     9781 taaggccatg atacttccga aattttcagc cggttattcg ctggaaagga cccttggaca
     9841 aaaatatcag ggaataagtg tggggatttc catcccttta tgggagaata agaatcgggt
     9901 gaagcaggct aaagccggtg ttgtggcggc acaggccaga gagcaggata gcaaacagca
     9961 gttctatgac aggctccgga atttatatat gcgtgccagt ggtctccagc agacagccat
    10021 tgcctatcgt gagtccctca aggcactcaa taataccgcg ttactgatga aagcactgga
    10081 tgtgggtgag atatccttgt taaactatat cgttgagata ggcctgtatt atgacacagt
    10141 taatcagacg ttggctgccg agcgtgattt tgaaaaggct ttggcagatt tgtctgctgt
    10201 tgaactctaa aaaaacgacc tatgagaaaa ctaaaaaagc catattctca aaattggaga
    10261 ggtctgtctg ccaaatggct gtttattttg tctactgttt tagggattat agcagggact
    10321 tgtttttgga tttttatttc tcgctgtgga aatgaggagt gttttttaaa ttatgatcca
    10381 ttgccggaaa tgtttattgg tggcgtaata ggagcgtttt tatatgttat catatggggt
    10441 atgacgtctg atatgtgata tggtttagga agtcctgcat gaacg
//
