LOCUS       c00201_gnlPro..        12029 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPNDKLOK_203.
ACCESSION   c00201_gnlPro..
VERSION     c00201_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 18:06:58
            Original ID  :: gnl|Prokka|PPNDKLOK_203
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12029
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12029
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4650:11870]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4651..11870
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12029
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12029
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..1192
                     /locus_tag="ctg201_1"
                     /transl_table=11
                     /translation="SGIILYFCATTIQNSDMMTRFSFVLFALISLLLTACQDKQKVVSN
                     TENGTSVPLSYAQGFGITHSSGYTTITVYNPWKPGEIYDTYYLVKNEGQAVPTDGLKVV
                     IPLKSIMTNSATHLGFLELLGELDKVTGVCNSNYIYNPTILQGVKDGTIKDLGDAFNLD
                     IENLLLLHPQAVMTSAYNAEDENGRRMKQTGLPILYNIEWQEKSILGRAEWIKFIGAFF
                     DKEKLADSIFSQIAEQYNEIKKKAEKLSYSPSILSGQDYRGTWSMPSGRSYNAQLFRDA
                     GANYYYANDTTVSGSISSSIEEALIHFNQADIWVGVQANTLEDLGKMDPKYKLFKSYKN
                     GNVYHINKRTNITGGNDYWESGVARPDLLLNDMIKIVHPSLLPEYELTYMDKLKSK"
     CDS             1189..2193
                     /locus_tag="ctg201_2"
                     /transl_table=11
                     /translation="MKHYRLFLLLIGLLVLAFLADIAIGSVSLSIRDVWNTFIGSNDNL
                     IYREIILNHRLPKALTAILAGASLSVAGVLMQTLFHNPLAGPDVLGVTSGASLGVALLT
                     LGTSSLPLWLITGWGQVTAAIIGAIGVLLLVIIVSIKIPQTISLLIIGMMFGNFAGAIV
                     SILQSMSNPDTLKLFITWTFGSLSSVGWEQMSVMAPVIACGILTALLLQKQLNILLLGK
                     NYANGLGVSVPRLRLWIILATALLAGTSTAFTGPIAFIGITMPHVARGLFGSPNHRIIL
                     PASMLCGAITLLVCDLISQLPGMQGTLPINAVTALFGSPIIVWIILRNSYINK"
     CDS             complement(2268..2378)
                     /locus_tag="ctg201_3"
                     /transl_table=11
                     /translation="MEGPALLLVIYSNAKGMLTSIPFAFEYSRLMQKVSL"
     CDS             complement(2390..3181)
                     /locus_tag="ctg201_4"
                     /transl_table=11
                     /translation="MKKVLLSICMVSAVFAMSSCGSTKEAASLSSLNGEWNIIEVNGSA
                     IVPAENQELPFIGFDTATGKVYGNSGCNRMMGSIDLNSKPGTIDMSRLGSTRMACPDMT
                     TEQNVLNALGQVKSYKKLGKHNMALCNASNRPVVVLQKKASDVKLSALNGEWKIEEVNG
                     EAIPSGMEKQPFINFDVKKKSIHGNAGCNLINGGFETDKENPRSISFPNVISTMMACPD
                     MEVEGKVMKAINEVKSFDVLSGGGIGFYSADGTLVMVLVKK"
     CDS             3306..3890
                     /locus_tag="ctg201_5"
                     /transl_table=11
                     /translation="MKRRLRTLLLLLLIATRTLLAQNSHFASSSSPGSLSPDEETDFIT
                     THFPLKQLCKWTPGMKFMFIPDSSDEFVPILCKYEDGKEVDNDLLKSKTLEYTGSEETV
                     HETYIGKIYTSRFIFQCEDHKYYYEMKDVKLNDLCDQNPYASIPALVYLQDVNKAKELL
                     IGKTLYTRTTIAKTDDANSYSGYREVNIAKG"
     CDS             4011..4556
                     /locus_tag="ctg201_6"
                     /transl_table=11
                     /translation="MEPADFQAEKRINYFPNAFSFTNPDVKTRESIQSKYIGQSVYPQK
                     TIRVKQTELLRYTPLHIKDVQPEKAGTSATLLLTDIQGNTYQVKVDLKYDPILKNEDFI
                     EDLFGFSDIRKKYPNISESNWLMLAKGEVKPGMTTEECKLAIGEPIEIRVRTDTRFETW
                     LYRGKILEFENGILLRAK"
     CDS             4651..5844
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg201_7"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.9e-42, bitscore:
                     135.4, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.1e-41,
                     bitscore: 132.1, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRVLIIGAGGVGTVVAHKVAQNADVFTDIMIASRTKSKCDDIVK
                     AIGNPNIKTAQVDADNVDELVALFNDFKPEMVINVALPYQDLTIMEACLKAGVNYLDTA
                     NYEPKDEAHFEYSWQWAYHERFKEAGLTAILGCGFDPGVSGIYTAYAAKHYFDEIQYLD
                     IVDCNAGNHHKAFATNFNPEINIREITQNGRYYENGQWVTTGPLEIHKDLTYPNIGPRD
                     SYLLYHEELESLVKNFPTIKRARFWMTFGQEYLTHLRVIQNIGMARIDEIDYNGQKIVP
                     LQFLKAVLPNPQDLGENYEGETSIGCRIRGLKDGKERTYYVYNNCSHEEAYKETGMQGV
                     SYTTGVPAMIGAMMFFKGEWKRPGVNNVEEFNPDPFMEQLNKQGLPWHEVFDGNLEL"
     CDS             5914..6360
                     /locus_tag="ctg201_8"
                     /transl_table=11
                     /translation="MNVGDKAPELLGINEKGEEVRLNNYKGRKIVLYFYPKDNTSGCTA
                     QACSLRDNYAELRKAGYEVIGVSVDNEKSHQKFIEKNNLPFTLIADTDKKLVEQFGVWG
                     EKKLYGRAYMGTLRTTFLINEEGVIERIIGPKEVKTKEHASQIL"
     CDS             6371..7414
                     /locus_tag="ctg201_9"
                     /transl_table=11
                     /translation="MAKKEDELNFETDNNKMASSEKLKALQAAMDKIEKSFGKGSIMKM
                     GEEVVEQVEVIPTGSIALNAALGVGGYPRGRIIEIYGPESSGKTTLAIHAIAEAQKAGG
                     IAAFIDAEHAFDRFYAAKLGVDVDNLFISQPDNGEQALEIAEQLIRSSAIDIIVVDSVA
                     ALTPKAEIEGDMGDNKVGLQARLMSQALRKLTSAVSKTRTTCIFINQLREKIGVMFGNP
                     ETTTGGNALKFYASVRLDIRGSQQIKDGEEVIGKQTKVKVVKNKVAPPFRKAEFDIMFG
                     EGISHSGEIIDLGADLGIIKKSGSWYSYNDTKLGQGRDAAKQCIADNPELAEELEGLIF
                     EKLREHK"
     CDS             complement(7480..7761)
                     /locus_tag="ctg201_10"
                     /transl_table=11
                     /translation="MKIFGEKDVLLMTELKIDTMSQNETTKLDIIVEVLGEREPEIRRL
                     VILDDRLRMFAESNDENGPGIPIELVAEWAMLLNKYYPLALEKRNMMN"
     CDS             7846..8361
                     /locus_tag="ctg201_11"
                     /transl_table=11
                     /translation="MDTESFKREFLPYHRKLYCVAYRLLENAADAEDLVQEAYLKLWDK
                     REGLSVISNPEAFSVTLVKNMCFDLLRSGKYVLSRQSVELSAAQDVFQPDNLEAREGVR
                     QIKDIIAHLPEQQQRIINMRDIKGCSYEEIEQVTGLNSINVRVLLSRARKKIREEFNKW
                     NNYESRRN"
     CDS             8342..8791
                     /locus_tag="ctg201_12"
                     /transl_table=11
                     /translation="MKVEEIERLLAEFYEGTTTESQEEVLRNYFRTTEVPGHLLKDKEI
                     FLNLCPDADQDIEVPAHLEDKLNLLIDEMAEKEQHFFRPNNSKNSWRWIGGVAATILLL
                     IGIGYGIDNLSKNVCPPTPQDTFSDPEEPESHGTKSSGSNHTPVF"
     CDS             complement(8681..10012)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg201_13"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.1e-08, bitscore:
                     22.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDIISGGEALMRSLEYHGVKTIFGYPGGSIMPVFDALYDHRET
                     LNHILVRHEQGAAHAAQGFARASGEVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTAFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVPWAVARAFYIAKSGRPGPVVLD
                     FAKNAQVEKAEYMPAKLDFIRSYVPVPETDPEAVKAAAELINGAERPLVLVGQGVELGN
                     AQQELRAFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNMNTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEINKNVHADVAVLGNCKETLSAVTALLQPNE
                     HKEWLDSFLPYEQVEEEKVIRPELHPMGDTLSMGEVVRAVSDATNHEAILVTDVGQNQM
                     MSARYFKYSKDRSMITSGGLGTMGFGFFRIGECILWGGWAHIFA"
     CDS             complement(10068..11870)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg201_14"
                     /sec_met_domain="ILVD_EDD (E-value: 2.8e-217, bitscore:
                     712.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKEQLGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKKEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGELDGQHLDLID
                     AMIKSADESVSDEEVSKIENRACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ANRTQLFKDAAKLIVENTYKYYRDGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAIAHEAEADFKMDDIDMLSRKSPCLCKVAPNTQKYHIQDVNRAGGIMGIMGQLAKAG
                     LIDTSVVRIDGMTLGEAIDKYDITSPNVCEEAIKKYKSAAAGKFNLVLGSQDVYYKELD
                     TDRAEGCIRDIEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACNGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIKDGDIIEINIPERTINVRLTDEELAARPMTPVTRERY
                     VPKSLKAYASMVSSADKGAVRLID"
ORIGIN
        1 atccggaata atcttgtatt tttgcgccac gactattcaa aattcagata tgatgacccg
       61 attttctttt gtccttttcg cattaatctc acttctgcta accgcttgcc aagataagca
      121 gaaagtagtt tccaacaccg aaaacgggac ttccgttcca ctttcatacg cccaaggatt
      181 tggtataaca cattcctccg gatacaccac aattacagta tacaatccct ggaaaccagg
      241 agaaatttat gatacctact atctggtgaa aaacgaaggt caggcagttc ctactgacgg
      301 actaaaagta gtaattcctc taaagagtat aatgaccaac tcagccactc atctgggatt
      361 cctcgaactt cttggagaac tggacaaagt cacgggagtc tgcaactcaa attacattta
      421 taaccctact atccttcaag gtgtaaaaga tggaacaata aaggatttag gtgacgcttt
      481 caatctggac atagaaaacc tacttctact acatccacag gccgtaatga cttctgccta
      541 caatgccgag gatgaaaacg gccggcgtat gaaacaaaca ggattaccca ttttgtataa
      601 tatcgaatgg caggagaagt ccatcttggg acgtgcagag tggattaagt tcataggagc
      661 ttttttcgat aaagaaaagc ttgctgacag tatctttagt cagatagcag aacaatacaa
      721 tgaaatcaaa aagaaggctg aaaaattatc atactctcct tccattcttt ccggacaaga
      781 ttatagggga acttggtcca tgccaagtgg aagaagctac aatgcgcaac tctttcgcga
      841 tgcaggtgcc aactactatt atgccaatga caccacagtt tccggaagta tatccagtag
      901 tatcgaagaa gctttgatac acttcaacca agctgatatc tgggtaggtg tacaagccaa
      961 cacactcgaa gatttgggaa agatggatcc caaatacaaa ctatttaaat cctataaaaa
     1021 tggtaatgta tatcatataa acaaacggac aaacattacc ggaggaaacg attattggga
     1081 aagtggagta gcccgcccgg atctgttatt gaatgatatg attaaaatcg ttcatccgag
     1141 cctattaccg gagtacgaat tgacctacat ggataaatta aagagtaaat gaaacactac
     1201 cgactgtttt tactattaat aggattgtta gttttggcct ttctggcaga tatcgccatc
     1261 ggaagcgtta gcttgtctat acgtgacgta tggaatactt ttatcggtag caacgataac
     1321 cttatctacc gggaaatcat cttgaaccac cgactcccta aagcactgac agccattttg
     1381 gcaggagcct cactctccgt tgccggagtg ttaatgcaaa ctctgtttca caacccactg
     1441 gctggtcccg atgtgttggg agtaacttcc ggtgccagct taggagtagc cttactgact
     1501 ctcggcacct cttctcttcc gttgtggctc attacaggtt ggggacaagt gactgctgct
     1561 attattggag ctataggggt tttattattg gttattattg tctctatcaa aattcctcaa
     1621 accatctcgt tactgattat aggtatgatg tttggtaact ttgccggtgc catcgtgagt
     1681 atcctgcaaa gtatgagtaa tccggatacc ctgaagctat tcatcacctg gacttttgga
     1741 agtctttctt cagtaggctg ggaacagatg agcgtgatgg cacctgtcat tgcctgtgga
     1801 attctgactg cattactatt acaaaaacaa ctcaacatct tgctgctggg aaaaaactac
     1861 gccaacggat taggggtctc cgttcctcgg ctgcggcttt ggattatcct ggctacagca
     1921 ctcctggcag gaacctccac tgcttttacc ggtcccatag cctttatcgg catcacgatg
     1981 cctcacgtag cccgtggctt attcggcagc cccaaccacc gcatcattct tccagcctcc
     2041 atgctctgtg gtgccatcac actgttagtc tgcgatttaa tttcccaact acccggaatg
     2101 caaggtaccc tacctatcaa cgcggttact gccttgtttg gatcccctat tatcgtatgg
     2161 atcatactac ggaattcata tatcaataaa tagaagtaca cgaatagact attttcactg
     2221 gagtacaaga ctacttaatg aactaatgtg actgtctagt attccattta caaagatact
     2281 ttctgcatca gcctactata ttcaaacgca aaggggatgc ttgtaagcat cccctttgcg
     2341 tttgaatata tcactaataa gagagcaggt ccctccatca agcgtttttt tattttttca
     2401 caagtaccat taccagtgtt ccgtctgcac tataaaatcc gatacctcct ccggataaca
     2461 catcgaatga cttcacctcg ttgatagctt tcatcacttt gccttccact tccatatcag
     2521 gacaagccat catagtagaa ataacattag ggaaagaaat ggaacgggga ttctccttat
     2581 ctgtttcaaa tcctccatta atcaaattac atcccgcatt gccatgaatg gacttcttct
     2641 tcacgtcaaa attgataaac ggttgttttt ccatgcccga agggatagct tctccattca
     2701 cttcttcgat tttccattca ccattcaaag cagacaactt tacatccgaa gctttcttct
     2761 gaagaacgac taccggacga ttggaagcgt tgcaaagagc catattatgt ttacccagtt
     2821 ttttataact cttcacctgt cccaatgcat tcagcacatt ttgttctgtt gtcatatccg
     2881 gacaagccat acgggtactc cccaatcggc tcatatcgat agtaccgggt tttgaattga
     2941 gatctataga tcccatcata cggttacaac cactattacc atatacttta cccgtagctg
     3001 tatcaaaacc aataaacggc aattcctgat tttctgccgg cacaatggcc gagccattca
     3061 cttcaataat attccattca ccatttaaag atgataaaga agcggcttct tttgtcgaac
     3121 cgcaagatga catagcgaat actgcactca ccatacaaat tgaaagtaat acttttttca
     3181 ttgtcatact gtttaagtta aatatcggcg caaatatata aaaaaataac ataaagttga
     3241 tacatttgcc gaattaagat aaacagaaca aacaaacgaa tagttcaatt taacaaaata
     3301 taatcatgaa aagacgcctc agaaccttat tactccttct tttgatagcc accagaacat
     3361 tacttgcaca aaacagccat tttgcaagtt cctcctcccc cggctcccta tcacccgatg
     3421 aagaaacgga tttcataaca acacatttcc ccttaaagca gttatgtaaa tggacacccg
     3481 gaatgaagtt tatgttcatc cccgatagta gtgatgaatt cgtccccata ttatgcaaat
     3541 atgaagatgg gaaagaagtc gacaacgatt tgctcaaaag taaaacgctg gaatataccg
     3601 gttcggaaga aactgtacat gaaacgtata tcggcaagat ttatacttcc cgattcatat
     3661 tccagtgtga agatcataaa tactattatg agatgaaaga tgtcaaactg aacgatttgt
     3721 gtgatcaaaa tccgtatgcc agcatccctg ccctcgtcta tctgcaagat gtaaacaagg
     3781 ccaaggaatt attaattggg aaaacgctct atacgcgtac taccatagca aaaacagacg
     3841 atgccaacag ctattcagga tatagagaag tcaatatcgc gaaaggttaa cctgtcaaaa
     3901 ttacaacaat agatgtcggt aacaagtcct tcccggtaaa aatcactttt attgaccgca
     3961 agggagtttc ttattatatt gatgtagcca tgtccagaac caactccggt atggaacctg
     4021 cagattttca agcggagaaa agaataaact attttccaaa tgcattttct ttcaccaatc
     4081 cggatgtcaa aaccagagag tctatccagt ccaaatacat cggacagtct gtttatcctc
     4141 aaaagacaat tcgggtcaag caaacagagt tattacgtta taccccatta catatcaaag
     4201 atgtacaacc tgaaaaggca ggaacatcag ctacactcct tctcacagat attcaaggaa
     4261 acacatatca agtcaaagta gatttgaaat atgatccgat ccttaaaaat gaagatttca
     4321 tagaggacct tttcggattc tccgacatac gaaagaaata tccaaacatt agtgaatcca
     4381 actggcttat gcttgccaaa ggagaagtaa aaccgggcat gacaaccgaa gaatgcaaat
     4441 tagcaatagg agaaccgata gaaatcagag ttcggacaga cacccgcttt gaaacctggt
     4501 tatatagagg aaagatattg gaatttgaaa atggcatctt gctccgggct aaataaagaa
     4561 acttaaatcg tcgaatattc tgaaataatg ccgtatattt gttccatcaa caattcttaa
     4621 attcttaatt taaaattcgt aattaaagaa atgggtagag ttcttattat cggtgcaggc
     4681 ggtgtaggta ccgttgtagc acacaaagtg gcacaaaatg ccgatgtatt tactgatatc
     4741 atgatcgcca gccgcacgaa gtcaaaatgt gacgacatcg tgaaagccat cggcaatccc
     4801 aacataaaaa cagcccaagt ggatgctgat aatgtggacg aactggtagc actcttcaac
     4861 gattttaaac cggaaatggt cattaacgtt gcattgcctt atcaggacct gaccatcatg
     4921 gaagcctgcc tgaaagcagg agtcaactac ctggataccg ctaattatga gcctaaagat
     4981 gaagctcact ttgagtacag ttggcaatgg gcctatcatg aacgtttcaa agaagccggc
     5041 ctcaccgcca ttttaggttg tggattcgat ccgggagtaa gtggtattta tacggcatat
     5101 gccgccaaac attattttga tgagattcaa tatctggata tagtagactg caatgccgga
     5161 aatcatcata aagcttttgc aacaaacttc aatccagaaa tcaatatccg cgagatcacc
     5221 cagaacggac gttattatga aaatggccaa tgggtgacca caggtccact ggaaattcat
     5281 aaagatctga catatccaaa catcggtccc cgtgattcat atctgttgta tcacgaagaa
     5341 ttggaatcat tagtcaaaaa cttcccgacc atcaaacggg cacgtttctg gatgacattc
     5401 ggtcaggaat atctgactca tttgcgtgtg attcagaata tcggaatggc gcgtattgac
     5461 gaaatagatt acaatggaca aaagatcgtt ccgctgcaat tcctgaaagc cgtgttacct
     5521 aatcctcagg atttgggtga aaattacgaa ggtgaaactt ctatcggttg ccgcattcgt
     5581 ggtctgaaag atggcaaaga acgcacttac tatgtatata ataactgtag tcacgaagag
     5641 gcatataaag aaacaggtat gcaaggagta agttatacca caggcgtacc ggctatgatc
     5701 ggtgccatga tgttctttaa aggcgaatgg aaacgtccgg gtgtaaacaa cgtggaagag
     5761 tttaatccgg atccgtttat ggaacaattg aataaacaag gcttgccttg gcacgaagta
     5821 ttcgatggaa atttggaact gtaatcaaca taacaatatg cctaacccta agtaagtcaa
     5881 tcggcatatt tattattgga agaatcatca aaaatgaatg taggagataa agccccagaa
     5941 ctgctgggta tcaatgaaaa gggtgaagag gtgcgcctca acaactataa aggaagaaaa
     6001 atcgtccttt atttctaccc taaagataac acttccggct gtacggccca agcttgtagc
     6061 cttcgggata attacgcaga gctacgtaaa gccggatatg aagtgatcgg tgtaagtgta
     6121 gacaatgaaa agtcacacca gaaatttatt gagaaaaaca atctgccatt caccctgatt
     6181 gccgatactg ataaaaaatt ggtagagcaa tttggagtat ggggagaaaa aaagctatat
     6241 ggccgtgctt atatgggtac tttacgtaca actttcctta tcaatgaaga gggagttatc
     6301 gaacggatca tcggacccaa agaagtaaag accaaagaac acgcttcaca aattttataa
     6361 atcgatcatt atggcaaaga aagaagacga attaaacttt gaaacagata ataataaaat
     6421 ggcatcaagc gaaaaattaa aagccttaca ggctgccatg gacaagatag agaaaagctt
     6481 cggtaaaggt tctatcatga aaatgggtga agaagtggta gaacaagtag aagtaattcc
     6541 aacaggttcg atagcactga atgctgcatt aggcgtaggc ggttatcccc gtggaagaat
     6601 cattgaaatt tatggtccgg aatcatccgg taaaacgaca ctggccatcc acgccattgc
     6661 agaagcacaa aaagccggtg gaattgccgc tttcattgat gcggaacatg cttttgaccg
     6721 cttctatgcg gctaaactgg gagtagatgt ggataacctg ttcatctcgc aacccgataa
     6781 cggagaacag gcgttggaaa ttgcagagca attgatacgc tcttcagcta ttgacatcat
     6841 cgtagtggac tctgtagccg ccttgactcc gaaagctgaa attgaagggg atatgggtga
     6901 caacaaagtg ggcttgcaag cccgcctaat gtcacaggca ttacgtaagt taacatcagc
     6961 tgtaagcaag actcgtacaa cctgtatctt catcaaccag ttgcgtgaga aaatcggtgt
     7021 aatgttcggt aatccggaga caacaaccgg tggtaatgca ttaaaattct atgcttccgt
     7081 acgtttggat atccgcggtt cacagcagat caaagacggt gaagaagtga ttggtaagca
     7141 gacgaaagtc aaagttgtga aaaataaggt agctcctcct ttccgcaagg cagaattcga
     7201 tattatgttt ggtgaaggca tatcacattc gggagaaatc attgacctgg gagcggattt
     7261 gggaattatc aagaaaagcg gttcatggta tagctacaac gacacaaaat tgggccaagg
     7321 tcgcgatgca gcaaaacaat gtatcgccga caatccagaa cttgccgaag aactggaagg
     7381 actgatcttt gaaaagttga gagagcacaa gtaagtgtaa tcaataaaca acgatcggca
     7441 gtgttctatc gaacaaccgc cgatcgttta ttatatatct taattcatca tattccgttt
     7501 ttccaatgcc aacggataat atttattcag cagcatagcc cactccgcta ccaactcgat
     7561 aggtatgccc ggaccatttt catcgttaga ttcggcaaac atccttaacc ggtcgtccaa
     7621 gataaccaaa cgtcgtatct ccggctctct ctcacctaat acttctacaa taatgtccaa
     7681 ttttgttgtt tcattttgac tcatagtatc tatttttaat tcagtcatta aaagtacatc
     7741 tttttcgcca aagatcttca tcttacttat tcttttttcg ctttctttgt aacaaaattc
     7801 ctcccgttac gtcttaagga tataaacatt gacaagaacg aacacatgga taccgaaagt
     7861 tttaaaagag agtttctacc ctatcatcgc aagctgtact gcgtggccta tcggctattg
     7921 gagaatgctg ctgatgcgga agacttagtg caagaagcct atctgaagtt gtgggataaa
     7981 cgggaaggac tgtcggttat cagcaatcct gaagcattca gtgtcacttt agtaaaaaat
     8041 atgtgttttg atttgcttcg ttcaggaaag tatgttctgt cccgacaaag cgtggagcta
     8101 tcagccgccc aagatgtttt tcaaccggac aatctggaag cacgtgaagg ggtacgacaa
     8161 ataaaagata ttattgccca cttacccgaa caacagcaac gaatcataaa tatgcgcgat
     8221 attaaaggtt gttcatacga agagatagaa caagtcactg gattaaactc tataaacgtc
     8281 cgtgtgctac tgtcacgggc aagaaaaaag atacgtgaag aatttaataa atggaataat
     8341 tatgaaagtc gaagaaattg aaaggctgct cgccgaattt tatgagggga ccactaccga
     8401 gagccaagaa gaggtgctga gaaattattt cagaacaacg gaagtgcccg gacatctgct
     8461 gaaggacaaa gaaatttttc tcaatctttg cccagatgcc gaccaagata tagaagttcc
     8521 tgcacatctg gaagacaaac taaatctgct gattgacgaa atggccgaga aagaacaaca
     8581 ctttttccgc cccaataact ccaaaaacag ctggcgctgg attggagggg ttgcagctac
     8641 catattattg cttataggca ttggatacgg gattgacaat ttaagcaaaa atgtgtgccc
     8701 acccacccca caagatacat tctccgatcc ggaagaaccc gaatcccatg gtaccaagtc
     8761 ctccggaagt aatcatactc cggtcttttg aatatttaaa gtaccgggca gacatcatct
     8821 ggttttgacc gacatcggtc accaatatcg cttcatgatt ggtcgcatcg cttaccgcac
     8881 gcaccacttc ccccatcgaa agcgtatctc ccatcggatg caattccgga cggattacct
     8941 tttcttcttc cacctgttca taaggcagga aactatccag ccattcttta tgctcgttgg
     9001 gctgcagcaa tgccgtaaca gcagagagcg tctctttaca gttacccaga accgctacat
     9061 ccgcatgtac attcttatta atttcagccg gatcgatatc aaaatgaatc actttcgcct
     9121 gcttggcgta cgtagccagg tttccggtca cacggtcgtc aaaacgcatc ccgacagcaa
     9181 tcaggacatc acatttatta gtgttcatat tcggtccgag attaccgtgc attcccagca
     9241 tacctttgtt caaaggatgc tcggtcggca aagccgacag tcccaacaac gtacatccgg
     9301 cgggcatatc tgccttttcg atgaaagcac gcaattcctg ttgtgcgttg cccagttcca
     9361 caccttgccc caccaatacc aacgggcgct ctgcaccgtt aattaattcg gcagccgctt
     9421 tcacggcctc cgggtcagtc tcgggtacag gcacgtaact gcgtatgaaa tcgagtttcg
     9481 caggcatata ttcggctttc tccacctggg cattttttgc aaagtcgagc actaccggtc
     9541 ccgggcgtcc gcttttcgct atataaaagg cgcgggccac cgcccatggc acatcttcgg
     9601 cacgacggat ctgataactc cattttgtaa ttggctgcgt gatgcctacc aagtcgacct
     9661 cctgaaaagc atctgtcccc aaaaaagctg ttcccacctg tccggcaatg actacaatcg
     9721 gtgtactgtc gatcattgca tccgcaatac cggttatggt attggtagca ccggggccgc
     9781 tcgtcaccag gcaaactccg acctcacccg aagcacgggc aaatccctga gccgcatgtg
     9841 ccgccccttg ttcgtggcga accaaaatat gattcaaagt ctctctatga tcgtataagg
     9901 catcgaatac gggcatgata gatcctccgg gataaccaaa gatcgtcttt acaccatgat
     9961 attccaaaga acgcattaat gcttcaccgc ctgaaattat atctttactc atgtactaaa
    10021 atttacgatt ttacgattta caatttacga ttgaaacaac tctgtggtta atcaatcagt
    10081 ctcaccgctc ctttatcggc agagcttacc atgctggcat acgctttaag acttttaggc
    10141 acatagcgtt cacgagtgac cggagtcatc ggacgtgcag ccagttcttc atcggtcagt
    10201 cgcacgttga tagtccgttc ggggatattg atttcgatga tatcaccatc cttaatcttt
    10261 ccgatattac ctccggctgc tgcttcggga gagatatgcc cgatgctgag tcccgatgta
    10321 cctccgctga aacggccgtc ggttatcagc gcacactcct tgcccaagtg gcgcgatttg
    10381 atataagagg taggataaag catttcctgc ataccgggac ctcccttcgg accctcgtgc
    10441 gtgatgacga ctacatctcc gctgacaact tttcctccga gtatcccatt gcaggctgct
    10501 tcctgtgaat cgaacacctt tgccggaccg gtaaacttcc agatgctctc gtccactccg
    10561 gccgttttca ccacacaacc atcctgggca atatttcctt tcagtacggc cagtcctccg
    10621 tctttgctat atgcgtgctc tatgtcgcga atacaccctt cggcacggtc cgtatccagc
    10681 tctttataat agacgtcctg agagccgagc accagattga actttccggc agccgcactc
    10741 ttatactttt taatagcctc ttcacatacg ttcgggctag ttatatcata tttatctatc
    10801 gcctcaccca atgtcatccc gtcgatacgc actacagacg tatcgatcaa tccggctttg
    10861 gcaagttgtc ccataatccc catgatacct ccggcacggt ttacatcctg aatatgatac
    10921 ttctgtgtat tcggcgccac cttacacaag catgggctct tgcgtgaaag catatcaata
    10981 tcgtccattt taaagtccgc ctccgcttca tgggctatcg ccagcaggtg aagtaccgta
    11041 ttggtagatc ctcccatcgc gatgtccagc gtcatggcat tcaggaatgc ctcacgggtg
    11101 gcaatgctcc ggggaagtac gctttcatca ccgtcccgat aatatttata ggtattttct
    11161 acaatcagtt tcgcagcatc tttgaacaat tgggtacggt tggcatgagt cgccacaatc
    11221 gttccgtttc cggggagagc cagaccgatc gcttcgttca ggcagttcat cgaattggcg
    11281 gtaaacattc ccgaacaaca tccgcaagtg ggacaggccc gattctcgat cttggagact
    11341 tcttcatcac tcacactttc gtcggccgac ttaatcatcg catcaatcag gtccaaatgc
    11401 tgtccatcca gttcaccggc ttccatcgga cctccggata caaatacagt aggaatattc
    11461 agtctcatag ccgccatcaa catccccgga gtgattttgt cacaattgct gatacatacc
    11521 atggcatccg ctttatgggc attcaccata tattccacac tatcggcaat gatatcccgg
    11581 gaaggaaggg aataaagcat tccgtcatgt cccatggcaa taccatcatc aatggcaatc
    11641 gtattgaatt ccgcagcaaa gcatcccagc ttctcaattt cttttttcac cagctgacct
    11701 atttcatgta gatgtacatg tcccggcaca aactgagtaa acgaattgac gatggcaatg
    11761 ataggtttgc ctaattgctc ttttttcata ccattggctg cccaaagtgc ccgggcgcct
    11821 gccatgcggc gaccctgtgt gctgaacgaa ctgcgtaact gctttttcat ttcaatattc
    11881 cttttaagta aagagccttc cccactgtag tgagaaaggc tctaaatcat atcttctatc
    11941 tgtacgaata catacataac ctttctcacg ctcttgatgg aatcaccacg acgcgaataa
    12001 tatgcaggac tgccaggtta attgatgta
//
