LOCUS       gnlProkkaNJCBKDEP_77   10446 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NJCBKDEP_77.
ACCESSION   gnlProkkaNJCBKDEP_77
VERSION     gnlProkkaNJCBKDEP_77
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:55:01
            Original ID  :: gnl|Prokka|NJCBKDEP_77
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1436
            Orig. end    :: 11882
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..186)
                     /locus_tag="ctg59_5"
                     /transl_table=11
                     /translation="MSFRKMSSFIVGGGFLFAIVWVILSDLDLLPHISFIDRYYLIFLV
                     IFIVVCEKSQKNKPTN"
     protocluster    1..10446
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:5446]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5446
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10446
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10446
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(390..659)
                     /locus_tag="ctg59_6"
                     /transl_table=11
                     /translation="MTKSKKSQRMIMILALSAIQVIILSILYRIINPKEFVSMIYQVST
                     NNTMRFVIIAVILFTFIASMISSSLLVSVFDFLRSDLFKKGNSK"
     CDS             complement(770..1627)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_7"
                     /sec_met_domain="Abi (E-value: 2.9e-12, bitscore: 39.3,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKAGFVNLDEGDGMEKKRQRLFTLGLRVLYIFILDEFIEAFVF
                     TPFLSFLQLDFWADIVLYKVLSLVIILGLNLLLLRQKIIFRTSFGWPSWQKFVFWDIVG
                     CLVAWQIFTNRNFLDIFQASVIGTIAAVPEEYLYRGVIFGGLLRAFYLANRGGTRRNFI
                     YCMLLSSLAFSLAHLSNLPSQGAVATVGQMIQVSGMGMLLAALYVRYGTLLMPIFVHFM
                     IDFLVTLIHGPYPSKLNGVSDETTLIIVSLIWAGIYLAISMWTLWHCHDKEGFMARLAG
                     QAIK"
     CDS             complement(2145..2477)
                     /locus_tag="ctg59_8"
                     /transl_table=11
                     /translation="MNMIQRNKVYFIMTGLNESFQKTATVSVMNTDAQEVINDALHILE
                     KENVLQNRAIDYALARLYSRFVRLIGLQGMKLSPEADQWWQQLKDFMENDIHEELSQVG
                     GPHFIT"
     CDS             complement(2729..2920)
                     /locus_tag="ctg59_9"
                     /transl_table=11
                     /translation="MALTLNKAIHYILVTGISGVFLFTLAAAMGWVNQGDFALPLLLLA
                     AGLTLLRETDAGYEKARH"
     CDS             complement(3236..3571)
                     /locus_tag="ctg59_10"
                     /transl_table=11
                     /translation="MTDKRETLMSMLSKAYANPTIKAEPALRALIETNAKKVDEGDDDK
                     AYVTAVTQLSHDISKYYLIHHAVPEELVAVFNYIKKDVPAADIDAAHYRAQALAAGLIA
                     IPIVWGH"
     CDS             complement(3690..4286)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 109.3;
                     E-value: 3.3e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_11"
                     /sec_met_domain="Mac (E-value: 1.7e-10, bitscore: 33.4,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEEKFAFMATGKPYDDMDPLLLAVRDEATAKTDALNNEHDPAK
                     RNALFRELVGQTGVKPFVNPNFHCEFGRNIRVGDHFYANYDCTILDGAPVTIGDHVLFG
                     PKVGLYTSNHLFDPLERQLGGCIAKPIVVGDGCWLAANVTVLPGVTIGAGTIIGAGSVV
                     THDIPARVIAAGNPCEVLREITAADKTGFAGHDMI"
     CDS             complement(4557..4865)
                     /locus_tag="ctg59_12"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNPYIVLTTLDGRLDFTFISMSNLKKLKSELMSLEIKSMD"
     CDS             complement(5001..5216)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_13"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3.9e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(5213..5446)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_14"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 8.7e-15,
                     bitscore: 47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(5718..6671)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.7; E-value: 5.1e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_15"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             6876..7610
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 3.9e-12. Score:
                     38.3. Matches aSDomain: nrpspksdomains_ctg59_16_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.9; E-value: 1.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_16"
                     /sec_met_domain="adh_short (E-value: 1.8e-34, bitscore:
                     111.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        6894..7382
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg59_16_PKS_KR.1"
                     /evalue="3.90E-12"
                     /label="ctg59_16_PKS_KR.1"
                     /locus_tag="ctg59_16"
                     /protein_end="169"
                     /protein_start="6"
                     /score="38.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     CDS_motif       6897..6977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg59_16_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg59_16"
                     /protein_end="34"
                     /protein_start="7"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             7636..8799
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     285.9; E-value: 6.7e-87)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_17"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQIYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGLKTPADAEKAADSFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSMTSSNVPQD"
     CDS             complement(9061..10437)
                     /locus_tag="ctg59_18"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITAAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAIKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIKSGDVTAAQFDKWVDPLKMTRV
                     "
ORIGIN
        1 ttaatttgtg ggcttgtttt tttgactctt ttcacacacc acaataaaaa taacgagaaa
       61 gatcaaataa tagcgatcaa taaatgaaat gtgaggtaac aaatctagat cacttaaaat
      121 cacccaaact atagcaaata aaaagccgcc accaacaata aagctgctca tttttctaaa
      181 actcataaac agacccactc tctatcattc ttcaatgttt atttttgcaa taatacaaac
      241 ggttcatttg ccaattgagg agattaaatg catatagaca tcatgatccg ctgacttgaa
      301 ttatctgttc aacagttgca ataacacctt agtctggcaa agtgtttaag tgtgcacgag
      361 aaaacgaaag tcatattcac agatgaaaat catttagagt ttcctttttt gaataaatca
      421 ctcctcaaaa aatcgaatac agacaccaaa agagacgagc ttatcatgct cgctatgaag
      481 gtaaacaata tcacggctat gataacgaat ctcattgtat tgttagtgct aacttgataa
      541 atcatagaaa cgaattcttt tggatttata atcctgtaca gaatactgag tattattacc
      601 tgtattgctg acaaagcaag gatcataatc attctttgac tttttttaga tttggtcact
      661 tgattcagct cctctttttt ggatcttcct ataattaaat aagcgattag catatccagt
      721 aataaagttt tccgcaattg cgagtgaagg tgtccaagat actataaact tatttgattg
      781 cttggcctgc taaccttgcc atgaaccctt ctttgtcatg acagtgccat agggtccaca
      841 tggaaatggc caagtaaatg ccagcccaga tcaacgaaac gattatgagc gtcgtttcgt
      901 cacttacccc atttaatttg ctaggataag ggccgtgaat cagcgttacc aagaagtcga
      961 tcatgaaatg aacaaaaatc ggcatcagca atgtgccata acgaacgtag agagcagcca
     1021 gcagcatgcc catcccgctg acttgaatca tctgacccac agttgcaaca gcaccttggc
     1081 ttggcagatt actcaagtgt gcaagcgaaa acgccagact gcttagtaac atgcaataga
     1141 taaagttgcg cctggtacca ccacggttag caaggtaaaa ggcgcggagc aatccaccga
     1201 aaataacccc gcgatatagg tactcttcag gaacagcggc gatggtacca atgacacttg
     1261 cttggaaaat atctaagaag tttcgattgg taaagatttg ccaagccaca aggcagccca
     1321 caatatccca gaacacaaat ttctgccagc ttggccagcc aaatgacgtc ctaaagataa
     1381 tcttttgtct taacagcaac agattgagcc ccagaatgat aactaaacta agtactttat
     1441 agagcacaat gtctgcccaa aaatccagct gtagaaaact taaaaatggg gtgaacacaa
     1501 atgcttctat aaattcatcc aagataaaaa tgtataaaac ccgtaatcca agcgtgaaca
     1561 accgttgccg tttcttttcc attccgtcac cttcatccaa gttgacaaag ccggcttttt
     1621 ccgacattgc tatgaacaat ataccggtta atgaatggct tttagtcaac taattttaaa
     1681 cgtcgtgttt tcgccattta acgttgacga tcatccgtca aaaattcgct agcggtcatt
     1741 tattgacaaa aaaagccact tcactcggca aacgactcta ctctacgcta agccaagaag
     1801 aagtgacgct gcagtgttga aaaagtcgcg gagcttgcaa ttggcgcaat tcttcaccgg
     1861 tcacaaacac ctacatgccc tgccatccct ttaaaaaccc cgcaataatt tggtcagtgt
     1921 gtgaccaagc atctatcgca atcaatccta aaatcagcat tgtcaggaat ttacgtcagg
     1981 tcatcccgtc aatcatttgt tgcaaatcat cattctttat tcgatgcatc tcatcgtgct
     2041 ccttccccaa ccagtctaaa tcaagtggta agtcacagta taaacagcgt aacactcgac
     2101 ttccgacttc gcatttgcat gtgctaatat tgggaacaaa ccgatcaagt aatgaagtgc
     2161 ggtccgccaa cctgactcag ctcttcatga atatcattct ccatgaaatc tttcagttgt
     2221 tgccaccatt gatcagcttc cggcgataat ttcatcccct gcaacccaat taagcgaaca
     2281 aagcgagaat acaggcgagc taatgcgtag tcaatggctc tattttgaag cacattttct
     2341 ttttccaaaa tgtggagcgc atcattgatg acttcttgtg catcggtatt catgacactg
     2401 acggttgcag ttttttgaaa gctttcgttg agccctgtca taataaaata gactttattt
     2461 cgctgaatca tgttcatgat atgtcaccat ttcctttgat gtcgtgacaa tttttctata
     2521 gaaatgtttg aaaagtatcg atgctatggt ttttaggcaa agcaccggaa aacaatggct
     2581 ttatagcccg actgatggat cttgataccg tcttgtatct gaactctttt agatatgagt
     2641 catcgtaacc gattacattt taaaatcagt ttgtccttgt gtacagaaat tcggcttcac
     2701 gtttttctgc cttctaagca gacccaattc aatgcctcgc tttttcatat ccggcatcag
     2761 tttcccgcaa caacgtgagt cctgccgcca aaagaagtag tggcagcgcg aagtcgcctt
     2821 ggttgaccca gcccatggcg gcagccagcg taaaaaggaa gacaccactg atgcctgtca
     2881 ctaaaatata atgaattgct ttattcaacg tcagcgccat cttgtacccc ctccgtccag
     2941 atgaacttcg actttttctc gtggatgctt tcacgcacac tatactggat aattcacaca
     3001 acggcgcaaa ctttttttaa acgtagggtt ttgcccgatt aacgtcgctt ttttgtcaaa
     3061 tatcaaccaa attttctctt tatcgatctg ctactcggtt tttcttaact ggtgtcaaca
     3121 agcttcatgg caaaaaaata gccgcagatc ttagtctgcg acgttttttg gcaaatgata
     3181 actgattgat catcaacttt agcctcaccg tttaaaattc acagccccac ctcggctagt
     3241 gtccccaaac aataggaatg gcgattaagc cggctgccag tgcttgtgca cgataatgtg
     3301 ctgcatcaat atcggcagca ggtacatctt ttttgatgta attgaagacg gccaccagct
     3361 cttctggtac ggcgtgatga atcagatagt atttggaaat gtcgtgggac aactgagtga
     3421 cagccgtcac ataagcctta tcgtcatcac cttcatcaac ctttttggcg ttggtttcga
     3481 taagcgcccg taatgccggc tctgctttga tcgttgggtt agcgtatgcc ttgcttagca
     3541 tcgacattaa agtttcacgt ttgtctgtca tcctgcactt cctttcgatg attaacttgg
     3601 caattcatgc tcactcggag caccttagtc tttgtgaata ttgttaggat gcgcttgtcg
     3661 attgttaatt tcaagtatcg atttggcgtt tagatcatgt catgccctgc aaaccctgtt
     3721 ttatcagcag ccgtgatctc gcgcagcact tcgcaaggat tacccgccgc aatcacgcgc
     3781 gctgggatgt cgtgggtgac aacactacct gccccgataa tcgtccccgc accaatcgtg
     3841 acgccgggta gcaccgtcac attggcagcg agccaacagc catccccgac tacaatcggt
     3901 ttagcaatgc agccaccaag ttgtcgttca agtggatcaa aaaggtggtt gctggtgtac
     3961 aaaccgactt tcgggccaaa caaaacgtga tcgccaatgg tcaccggcgc cccgtccaaa
     4021 atggtacagt cataattggc ataaaaatga tcacctacgc ggatattccg gccaaactca
     4081 caatgaaagt ttggattcac aaacggtttg acgccagttt ggcctaccaa ttccctaaac
     4141 aaggcattgc gtttggctgg atcgtgttca ttgttaagcg catcagtttt ggcagttgct
     4201 tcatcccgca cagccagtaa caaagggtcc atgtcgtcgt atggcttacc agttgccatg
     4261 aaagcaaatt tttcttctag attcattgcg ccacccctct ttcttggctc aagtttacca
     4321 gacatttgcg cactgcgttg ataattgcca atatgttaag gtgtgcttat cggtacgcat
     4381 gaagtctaca aaaagccacc acttcttgaa gaaatggtgg cttgaaaaca atgacatcgc
     4441 ttctgcacac agaaccacgc ctgttttgtt acaaacagaa acatacagtt acagtcttca
     4501 tcgtcacaaa attctggcgt taggaaattt cagctacttc ctcggacttt atcagcttaa
     4561 tccatagact taatctcaag tgacattaac tcagatttta gcttttttaa atttgacata
     4621 gagataaatg taaagtcaag tcttccatct agagtagtga gaactatata agggttctgg
     4681 ggattgatta acctactcag ccccttacta gatagtttca aatcccgatt taacaaaagt
     4741 atcttggcaa tgactttgct tcttgctgcc ccttgccaaa gtcctccaac aaatggtgct
     4801 agataaaaag cgatcgtcgc cagtaaaatc aagataacta tgatgatact tattatctta
     4861 tccatttgta tttcctcttc cttttgcaca aatagactaa tttgaaatcg atctttgact
     4921 aagacaagaa aaagtgagca ctaccaaggt gttagttata ttgaacagtt gcgataggag
     4981 ctaaccgtct ttgtccaata ttaggctggg tgaatgtaat tagtgctgag acacaaggat
     5041 aatcctattg cagcgcctgc aacagttgta aatggattta atccagctgc ccctgctacc
     5101 gctcccccga tcgtggacac aatacaccca ctaggtttat tgcgtcgctt ggctcctcct
     5161 tggattaaga ccaaatcatg ctgttttaaa gtaatgccca cttctttact tatcattgca
     5221 tcccatctcc taagcattta atagctgacc caaccgctcc taagtttcca ccaactacgg
     5281 cgccgccgat tatcccaaaa ggaccaccag ctaggccagt aatcgttcct gatccaatac
     5341 cagccgtgat gccagtaaca aatgtagcag cacaatcaaa tttctttttc ccacctgaaa
     5401 cccctgacaa ctgaaaatcg tcgagctggc gataattata agacataatt ttcctttttt
     5461 cttcaaaaag caacaagtta ttttgtgtaa ggtcgacttt actgtcttta acatacatta
     5521 attatttgtg taaaatgcca aaatttttta aacgtaggaa atttccagtt taacgtcgtc
     5581 tttacactct tattgttcag ttgcgcttta aaagtcaaaa attcttaacg tttaaatctc
     5641 cttgcttggt aaaaacttca attttttgca aaaaaaatcg tctcagcaat ttgagacaat
     5701 tttttcatat catcaactta cggcaaatca ttccccgccg caaagtaaat gtcataccat
     5761 tcttgtcggg tcaacgtgat gtccgcgcct tccgcacttt ccttgatatg ttcaggattc
     5821 atagagccga gaatcacctg cacaccaact ggatggcgta atagccaagc gactgcgatt
     5881 gcatttttat tggtatggta gtggtcagcg actttctgca gttcatcatt caacgcctta
     5941 aacttcgggc tatcgatgaa ggtaccttca aacatgccgt attggaatgg cgaccaggct
     6001 tgtaaggtca tgtgtttgcg ttgcaagtat ggtaataggc tgccatcatg atcgacagag
     6061 gcagcgtcgg ccatgttggt gtgcatcccc gcattgacca tgccagtatg ggcaacggag
     6121 aattgaactt ggtcaatcag caaaggctgc cgaatgccgc tttcaagcaa cgcaatttgt
     6181 tcagggttaa agttggagac gccaaaatgc cgaaccttgc cactttgttc caatgcatca
     6241 aaggccgccg caacgtcatc gacttccatt aacggatctg gccgatgcag caagaccgaa
     6301 tcaaggtaat caacctgcaa ccgtttcaaa atgtgatcaa ccgctgacag taagtgatct
     6361 tttgaaaagt cgtaccgttt gccgaatacc aaactgccat gagagcgttt tggatcaacg
     6421 acgatcccga ctttcgattg aatgaataac tgatcgcggg aaacgctggc ttgcttcaag
     6481 gcttcaccaa aaacttcttc ggatttgcct tggccataaa tgtcggccga gtcgataaag
     6541 ttgatgccgt cattgtacgc actatccagc acattggccg ctttgtcggg ggccagcaca
     6601 ttcatccgca tgatgcccaa ggccacactt gacgcctgcc aattggatcc gcctaatcga
     6661 acttgtttca taaacacaaa actcccttcg atacgtcatt tcaaattatg ttactgacga
     6721 caagttaagt gtagccccta aagtccactt gaggtcaagc caatattaga atttcaataa
     6781 aacagcttgc atggtgctga gctgcgcggt aggttaagct gtgtctgtta cttatttttt
     6841 cttagcagga taagcccata aaggaggccg tgattttgac agttaaagat aaagtggttg
     6901 taatcacagg tgcatcgagc gggattggcg cggcaacggt acaagtgttg gccgaggctg
     6961 gtgcaaaact agtcatcggt gcgcggcgca cagaacggtt ggctgaattg gcggccagct
     7021 ttacggacgg tcaggtgctg tatcaacaaa ccgatgtgac cgaccagcag caagtgaaag
     7081 cgctgattga tttggcgttg gataagtttg gtcatgtgga tgttttgtat aacaacgctg
     7141 gcctgatgcc actttctgaa atggccgaac tcaaagtcaa cgaatgggaa cgtatgattg
     7201 acgtcaacat taaaggcgtc ttgtatggga tcgccgcggt tttaccgcct atgattgccc
     7261 aacacagtgg ccaaattatc acaacagact cagttgccgg tcacattgtt caccctggaa
     7321 ccgccgttta ctccggtacc aagtgggcta ttcaggcgat catggacggc ctgcgacaag
     7381 aacaagcggc taatcatatt aaaacgacca tgatctcgcc cggtgccgtg aatactgagc
     7441 ttttcagcac aattaccgat cctaagcgcc gtgaagctgt tgaagccgat gaaaaaaaca
     7501 atggcctcag cgcctcggat gttgccaagg cagttttgta tgccattgat caaccggcca
     7561 atgttgccat caatgaagtg ctcttacggc cagtcacgca agaacgttaa ttttcgtcta
     7621 aaggagtgtg attgcatgtc gggttatcat tttttaaaac cgttcacctt caagcaccaa
     7681 accatcacgt tgaaaaatcg cattgtcatt ccgccgatga caacgcgcct gtcgtttgaa
     7741 gacggcactg tgacgcggga cgaaatcagg tattaccagc aacgggccgg tggcgtcggc
     7801 atgtttatta ccggtaccgc caacgtcaat gcgcttggca aaggattcga aggtgagcta
     7861 agtgtcgctg atgatcgatt catccccggt ttgagcaaac tcgccgctgc gatgaaaaca
     7921 ggcggcacca aggctatttt gcaaatcttc agcgctggcc gcatgagcaa tagcaagatt
     7981 ctgcgcggtg agcagccagt cagtgccagt gcggttgctg cgccacgggc gggttacgaa
     8041 acaccgcgcg cattgacatc ggcagaaatc gaggccacta ttcacgattt tggtcaggct
     8101 gtgcgccgcg ccatccttgc tggttttgat ggcatcgaac tgcatggtgc caacacctat
     8161 ctgatacagc aaatctattc gccaaactct aatcgccgaa ccgatgaatg gggcggtgac
     8221 cgcgataagc ggatgcgttt tccgttggca gtcgttcatg aagcagaaaa agtgattgcc
     8281 acaattgctg accggccatt tttgttaggc taccgcattt cgccggaaga gttggaacag
     8341 cctggcatta ccttggatga taccttggcc ttaatcgacg ctttgaaaca aaccaagatt
     8401 gattacctgc acgtctccca aagtgacgtt tggcgaacct cattgcgcaa ccctgaggac
     8461 acagccatca tgaatgaaca aattcgtgac catgtcgccg gtgcttttcc agtgattgtg
     8521 gttggtggtc tgaaaacgcc agccgatgct gagaaagcgg cagattcctt tgacttggtc
     8581 gcgattggtc acgaaatgat tcgcgagccg cactgggttc agaaggtctt agaccatgac
     8641 gaaaaggcga tccgttacca gatcgcccct gctgatcttg aagaacttgg cattgcgccg
     8701 accttcctcg attttatcga aagtatttcc ggtggggcaa aaggtgtccc gttaacaact
     8761 gcgcagtcta tgacatcaag caacgtgcct caagattaat ctagcatttc aaatcatcgt
     8821 gcgagtcgag ctgtaaaaag ctcggctttt ttcttgccgt cttcaactta cgcgatggtg
     8881 cctggagcta ccagtgattt ataagtttta aatcaaggtg tgatcatcac ctgctcacgc
     8941 tcttatttaa acgcgttcac cagcgcagaa acctacacat aaggacctga aacctaaatg
     9001 gtcaaagccc gaccatttag gtttcaggcc acttatgttc cggtttctaa ccgcgccagc
     9061 tcacactctt gtcattttta acgggtcaac ccatttatca aactgcgctg ctgtgacgtc
     9121 gccgcttttg atggcggctg cttttaaatc gagattttct tgctcagcca attgcgcgat
     9181 ggcggcactt ttttcgtagc cgatgtgggg tgcgagggcg gtgaccagca tgagcgaatg
     9241 atcaacgagt gctctcatat gcggtgcgtg gatggtcaag ccggcagcta atttttcagt
     9301 gaaactcgtg actgttttgg ttagtagatc agccgactct aaaaaggtac tgatgataac
     9361 cggcttgtag acgttcaatt caaaattgcc ttgtgacgcg gccaccgtga tcgtcgtatc
     9421 gttgcccatg actcgaacag cggccatggt tagcgcttcg gcctgtgtgg gattcacttt
     9481 gcccggcatg atggaactac caggctcatt ggccggaatg cgcaactcgc cgtatccagc
     9541 acgtggacca ctggcaagga agcgaatgtc attggcgatt ttaagcagat cagccgctag
     9601 cgttttaatg gcaccatgaa caacgctaat ttctgagtga gccgctaaag cagcaaactt
     9661 attggttttc gctgaaagtg gtaattgata aacatcgctc aatcggcccg ccacaatctt
     9721 gccaaaatta gggtcagcgt taagccccgt tccgacagct gttccgccaa tggctaagta
     9781 aaaaagattg ggctgaagct gctttaaagc aatctgatca tgctccatca tggccaccca
     9841 tccgctgatt tcttggccaa acgttagcgg cgttgcatcc tgtaaatgag ttcgaccgat
     9901 tttaacaaca cgagcgtaag tgacggcttt tgaatataaa acactgcaca gttggttgac
     9961 agcgtgcagc aactgattca ctgcaatagc cgccgtaata ttcatcacag ttggaaaagt
    10021 atcattggag ctttgactgt gattcacatc atcattcggt aagatcggca agtcggggtt
    10081 gagttttgca gcttggtggc taatgacttc gttcacattc atatttgttt gtgtgccaga
    10141 cccggtttga taaacatgca gtggaaaatc tttttgcagt ttttcgtctg gcaaggccaa
    10201 caaggcatcg actgctcgcg tgattaattg gccttttggt gccggtaaaa catcagcggc
    10261 cacatttgct cgcgctgccg cttttttgag ttgcagcaag gccctaatca ctggcatcgg
    10321 catcaatgga ccagcctgaa aattatgccg gctgcgctct gtttgcggtc cccacaaagc
    10381 gtttgccgga atttcaactg gtcctaatgt gtccgtttct gttcgatatt tgctcatgtt
    10441 tacctc
//
