LOCUS       gnlProkkaPPHCJNEB_14   20332 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPHCJNEB_14.
ACCESSION   gnlProkkaPPHCJNEB_14
VERSION     gnlProkkaPPHCJNEB_14
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 02:58:17
            Original ID  :: gnl|Prokka|PPHCJNEB_14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 20332
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..174
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="MIXIFPNDLSVLRLMGALLIEQNEKWAAGPRYLNMTVYHGIEKDD
                     NSEEAGMLKLVK"
     protocluster    1..20332
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4012:10332]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4013..10332
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..20332
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20332
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(805..1749)
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MTRKVAVVGMGHVGATVAHYLVAGGFTDDLALYDTNEAKVRADAL
                     DLRDAMANLPFHTNLTVNDDSQLADCDVVISTLGKSKLVDTPDHDRFAEFKFTRTQVPL
                     VAKKLVDNGFHGKLVDVTNPCDVITSMYQKLTGLPKNHVMGTGTLLDSARMRACVGEAL
                     HVDSRSVVGFNLGEHGNSQFTAWSTVRVLGKRVLDLVDERHLDLTDMEERARQGGYMVY
                     KGKKYTNYGVATAAVRLTNALLSDARTEMPVSNYREEYGTYLSYPAVVGRDGVVEQLHL
                     DLTAAEKEKLATSAKYIKDRLSAEEQRAAQQDA"
     CDS             complement(2465..2689)
                     /locus_tag="ctg14_3"
                     /transl_table=11
                     /translation="MNSFCPAFFGHPNYFINIQVSIKRMFTSPDLVRLISSKAVRTILI
                     LLSINCDGFDSQLMTGANNPCSNFTTVSN"
     CDS             complement(2852..3415)
                     /locus_tag="ctg14_4"
                     /transl_table=11
                     /translation="MKIFTGRNPNLGLNNINPSNQLGNGVFNLHPGINLNEVKMIRGRQ
                     EFDRRRILVVNTLHQLDGQATNFDPPLRGQDNAKCKFNNLLVAALDRAVTFKEVHHMPV
                     LISNYLHFNMLRVLDVLFDIHLIRSKRLQRLILRLIKLVGELLVVIDDPHPPTATTISS
                     LNHDRVTILVSKILYLVNIFNIPR"
     CDS             4013..5887
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     94.1; E-value: 1.4e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_5"
                     /sec_met_domain="HMGL-like (E-value: 1.5e-36, bitscore:
                     118.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYVKDQPRVLLTDTTMRDAHQSLFATRMRTHDMLPAMKVYDRAM
                     PNLFSVESWGGATFDVCYRFLGEDPWTRLRLLKKYMPHTLQQMLLRASNAVGYQNYPDN
                     ELKRFIEHSAATGVDVFRIFDSLNWIDQMERSITYVRETGKIAEGTMCFTGDFLSPHEH
                     KYTLDYYMKLAQSLVDAGAQIIGIKDMAGLLKPKAAYELVGSLKAKFDVPVHLHTHDTT
                     GNGVPTYVAATNAGVDVVDVAMSSMAGTTSQPSLATFYYALEGDKRQPDLNMHNVAVLN
                     RYWSNVRPLYNDFSNGVNAPQPDLYQTEMPGGQYSNLKQQAQSLGINDFSLVEEKYREV
                     NQLLGDIIKVTPSSKVVGDMAIFMIQNHLDKDNILTKGQRVDFPESVVNFFAGDLGQPY
                     RGFPKDLQKVVLKDHPAITVRPGSLAKPVDFAAVKQELAAKINQEPSEDDLQGYIMYPK
                     VFTTYFRNHQRYGEVMDLDTTTYYQGMRPGEILHVKYGQGKEMIIKLDFVSAPDDDGDR
                     FLFFELDGRILKIKVKDNSMKDKVVSVSKADPDKSNEIGMPLNGNVVKVNVAEGDQVKV
                     GDVLVVTEAMKMESAVKAPFTGKVTKVYAKVGDALKSQDLLLTLTEDA"
     CDS             5902..6660
                     /locus_tag="ctg14_6"
                     /transl_table=11
                     /translation="MMYEFPRLTAHHIQTTDQPVVTSTNEMAKERLKVKDQPFLISARQ
                     QTAGHGKTSRKFYSPAGSGAYFTLALPFSYLAKSAGQVTVTAAVAAYEVLSKQFTVPIT
                     IKWVNDLYCERKKVVGILAEMEMTANNQPRGIVVGWGINLAAPTAPLPPALQLRAGWLG
                     TTSIDDHQRLQIVDAVAAHFLDLLANASWKHILQVYQAHQYLINKLLLVDTGAERVRGY
                     FDHITDDGWLCVQTDNGPRAFMTGTVRELV"
     CDS             complement(7659..8042)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144:thioesterase superfamily protein (Score: 100.2;
                     E-value: 1.1e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_7"
                     /transl_table=11
                     /translation="MNLLENLGIHQDLVTKDRVELSMPVQAKHLQPYGIVHGGINTVLA
                     ETAASLGANANVAPGRIAVGVNVTTQHIRAIREGEIFVVATPDHVGRTLQTWQARLLVN
                     DRLTATATITLMNVPAPTNNHKH"
     CDS             8077..8898
                     /NRPS_PKS="Domain: ECH (18-261). E-value: 4.2e-63. Score:
                     204.7. Matches aSDomain: nrpspksdomains_ctg14_8_ECH.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 197.1; E-value:
                     4.6e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_8"
                     /transl_table=11
                     /translation="MTSANWTPVKEYSEIIFERDDKIAKITMNRPEKHNAFTPVTVAEM
                     INAFNICRDDSTIGVIILTGAGDKAFSSGGDQSVRGNGGYVGPDHIARLNVLDLQHLIR
                     IIPKPVIAMVKGWSVGGGNVLQLVCDLTIAADNAMFGQTGPKVGSFDAGYGSGYLARVI
                     GHKRAKEVWFLNHFYTADEAYQMNWINKVAPLAEVESVTLDWCHEILKKSPTALRFIKA
                     AMNADTDGLAGLQQFAGDATMLYYTTDEGKEGRDAFNQKRDPDFDKFPKFP"
     aSDomain        8131..8859
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg14_8_ECH.1"
                     /evalue="4.20E-63"
                     /label="ctg14_8_ECH.1"
                     /locus_tag="ctg14_8"
                     /protein_end="261"
                     /protein_start="18"
                     /score="204.7"
                     /tool="antismash"
                     /translation="RDDKIAKITMNRPEKHNAFTPVTVAEMINAFNICRDDSTIGVIIL
                     TGAGDKAFSSGGDQSVRGNGGYVGPDHIARLNVLDLQHLIRIIPKPVIAMVKGWSVGGG
                     NVLQLVCDLTIAADNAMFGQTGPKVGSFDAGYGSGYLARVIGHKRAKEVWFLNHFYTAD
                     EAYQMNWINKVAPLAEVESVTLDWCHEILKKSPTALRFIKAAMNADTDGLAGLQQFAGD
                     ATMLYYTTDEGKEGRDAFNQK"
     CDS             8908..10332
                     /NRPS_PKS="Domain: AMP-binding (8-379). E-value: 2.4e-71.
                     Score: 232.3. Matches aSDomain:
                     nrpspksdomains_ctg14_9_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     307.2; E-value: 2.9e-93)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_9"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-75, bitscore:
                     245.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIPNWLLKQASLNPNRVAVNDGTTAYTFAQLVPLVAHRAGQIQA
                     QTDQPRVGVMTHNNLAGYLAALGVLAADKTIVWLNWRLAPEELSRQIGDAGLDLVLVDD
                     QLADRYYGGHRVLCSELTAGTAPAAVLTPTVDLDAVASIMYTSGTTGQPKGVLQTYGNH
                     LASAISSSLNLGVLPNDLWLCVAPIFHISGFSILMRGLIYGMGVRLVNHFDAQVVNQIL
                     EDEPVTIISAVPYMLKKMLEDVQANDHCYSSAFRLVLLGGGTIDRATLNACEESGLPIV
                     QCYGMTETCSQFVALSAEEAPYHLGSVGKPLFTTQLRLVGEHHEIEIQTPALTPGYLNQ
                     PAKFAAKHDGDWYRTGDVGHFDEDGFLYVDGRLDEMIISGGENIFPAEVENVLRQYPGI
                     QEIAVVGRNDQQWGAVPVAVVVSKQPVDFQQLEAFGREHLAHYKVPKVYLQTDALPKNA
                     SGKVQKFRLQDLVANA"
     aSDomain        8932..10044
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg14_9_AMP-binding.1"
                     /evalue="2.40E-71"
                     /label="ctg14_9_AMP-binding.1"
                     /locus_tag="ctg14_9"
                     /protein_end="379"
                     /protein_start="8"
                     /score="232.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="KQASLNPNRVAVNDGTTAYTFAQLVPLVAHRAGQIQAQTDQPRVG
                     VMTHNNLAGYLAALGVLAADKTIVWLNWRLAPEELSRQIGDAGLDLVLVDDQLADRYYG
                     GHRVLCSELTAGTAPAAVLTPTVDLDAVASIMYTSGTTGQPKGVLQTYGNHLASAISSS
                     LNLGVLPNDLWLCVAPIFHISGFSILMRGLIYGMGVRLVNHFDAQVVNQILEDEPVTII
                     SAVPYMLKKMLEDVQANDHCYSSAFRLVLLGGGTIDRATLNACEESGLPIVQCYGMTET
                     CSQFVALSAEEAPYHLGSVGKPLFTTQLRLVGEHHEIEIQTPALTPGYLNQPAKFAAKH
                     DGDWYRTGDVGHFDEDGFLYVDGRLDEMIIS"
     CDS_motif       9328..9378
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_9_0001"
                     /evalue="4.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg14_9"
                     /protein_end="157"
                     /protein_start="140"
                     /score="22.4"
                     /tool="antismash"
                     /translation="ASIMYTSGTTGQPKGVL"
     CDS             10380..11573
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 231.4; E-value: 2.3e-70)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_10"
                     /transl_table=11
                     /translation="MMDAKPNRRALSLGSFVILYLGYMLLFADRTVLNLSLAAIGKDFS
                     VSPAALGATSSVFFLGYTIMQIPGGWLTDRFSSRKVIIATLAFWSVMTIFTGLAWSLAA
                     LLVIRFLFGIAEGPYPPAAMKQVAQDFPVNKRAQLTAALISSNYAGAALAPFIIVPIIA
                     ATGWRSAFFWLGGFGLLLMVSYLFFRGHGGGQTVTKQERQKINWKEIDPRVWAFVVIGL
                     ALNIITKGMETWMPVYFLNARHINLANLAWLVPLPTIAGGIAALISGYVMVHIFKNQER
                     LMIILASFLTVLTMFGLYKSTSLVWLVIFQMATYFVKSLAFTGIFSYAAQLFPQKTYGS
                     QIGTINFGGQLGGFFGPLLIGWIVQLSGSYDTAFFGLVISALVAGVASLFIGNLKAK"
     CDS             11804..11950
                     /locus_tag="ctg14_11"
                     /transl_table=11
                     /translation="MKGFAMLGPNKTGFIEKEDPKVGSRDALVRPLAVAPCTSDIHTVF
                     EDA"
     CDS             11965..12873
                     /NRPS_PKS="Domain: PKS_ER (2-209). E-value: 3.2e-12. Score:
                     38.0. Matches aSDomain: nrpspksdomains_ctg14_12_PKS_ER.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 198.5; E-value:
                     2.2e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_12"
                     /sec_met_domain="ADH_N (E-value: 2.4e-11, bitscore: 35.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.8e-22, bitscore:
                     69.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILGHEACGVVVEVGEDVKDFKPGDRVLVPAITPNWSDVYSQAGY
                     ATDSDGMLGGWKFSNIKDGVFATRFHVNDADGNLAHLPDEIDPAEACMLSDMIPTGLHA
                     SEMAGVTFGDDVAVIGIGPVGLMALRGAVLHGAGRVFAVGSREKTVEVAKKYGATDIID
                     YHNGRISDQILEATGGQGVDKVLIAGGNAKDTFEEAVRMLKPGGSIGNVNYLNGHDDVV
                     FNAGDWGVGMGHKTIHGGLMPGGRLRMEKLAVLVVNGRIDPSLMITHRFEGFEKIPDAI
                     ELMHHKSADLIKPVVICNDID"
     CDS_motif       11971..12009
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_12_0001"
                     /evalue="6.00E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="ctg14_12"
                     /protein_end="15"
                     /protein_start="2"
                     /score="9.7"
                     /tool="antismash"
                     /translation="LGHEACGVVVEVG"
     aSDomain        11971..12591
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg14_12_PKS_ER.1"
                     /evalue="3.20E-12"
                     /label="ctg14_12_PKS_ER.1"
                     /locus_tag="ctg14_12"
                     /protein_end="209"
                     /protein_start="2"
                     /score="38.0"
                     /tool="antismash"
                     /translation="LGHEACGVVVEVGEDVKDFKPGDRVLVPAITPNWSDVYSQAGYAT
                     DSDGMLGGWKFSNIKDGVFATRFHVNDADGNLAHLPDEIDPAEACMLSDMIPTGLHASE
                     MAGVTFGDDVAVIGIGPVGLMALRGAVLHGAGRVFAVGSREKTVEVAKKYGATDIIDYH
                     NGRISDQILEATGGQGVDKVLIAGGNAKDTFEEAVRMLKPGGSI"
     CDS_motif       12370..12396
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_12_0002"
                     /evalue="5.30E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="ctg14_12"
                     /protein_end="144"
                     /protein_start="135"
                     /score="0.9"
                     /tool="antismash"
                     /translation="GAGRVFAVG"
     CDS             complement(13179..14429)
                     /gene_functions="other (smcogs) SMCOG1192:transposase
                     (Score: 270.4; E-value: 4e-82)"
                     /gene_kind="other"
                     /locus_tag="ctg14_13"
                     /transl_table=11
                     /translation="MKSMAQMKYHYGLKVRIYPSDRQKKIIKINSDASRFIYNEMVAIN
                     KELWRLKQVKLPIDTIQNRIEQLELRQSAKQMSNHFQFLEDKRIDSLTKANAIQNYHKA
                     WNAFRKVHTAGVPKFHRKSYVWRYQTNCQYLKQKAAYLTNGTVHFEDSKHVIVPKLGRL
                     RVKGSHQRVLARSAETRIGTVTIVKDASGRFFLSMQLASDTPFVNWPQNTGKQIGIDLN
                     TENFLTTSNGDTVANPRYYRIIKGRLAKAQRILSRRARRAKQEHRPLRTSKNYQKQRLL
                     VAKLHAQVFERRRDFLHNVSTTLIKNHDFVAAEELRSKNMLKNHALAMSIADVGWRTFL
                     GMLAYKAELYHRQFLTVDPKNTTQACHECGFVMGTAGTEKLTLADREWTCPKCHAHHVR
                     DHNAAQNILTKGIIKLA"
     CDS             complement(14915..15130)
                     /locus_tag="ctg14_14"
                     /transl_table=11
                     /translation="MMGGCAMQRQEKIELLKSLIRIDSDDGNELAVAELLATVLINIGR
                     NPVTLVMGWIGFYLRPLGRFFISLYF"
     CDS             complement(15251..16423)
                     /NRPS_PKS="Domain: Aminotran_5 (4-370). E-value: 2.7e-80.
                     Score: 261.8. Matches aSDomain:
                     nrpspksdomains_ctg14_15_Aminotran_5.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 296; E-value:
                     6.8e-90)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_15"
                     /sec_met_domain="Aminotran_5 (E-value: 7.2e-79, bitscore:
                     257.1, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.8e-09, bitscore:
                     28.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRIYIDNAGTTKTAPEVIETMTEALETTWGNASTTNYYGRQAK
                     QMLEDSRHLLARSINAQFDDEIVITSGGTESDNTVVKQVAKARQSEGRHIITTAFEHEA
                     ILRPLEDLEQEGFEVTYLPVDERGQISLADLKAALREDTILVTIMTVNNEVGSHLPIHE
                     IGQIVADSNAWFHTDAVQAYGTLPLDVQTDQIDLMSVSGHKLNGPKMVGFLYRRRGIVF
                     PSFVRGGDQELKRRAGTENVPAVVGFARAVELHQEKMAEHRATYVALKHQLVDGLKDAG
                     IDFEVNGSLDEGAAPQVLSLWFKGVPNDALLTNLDLEGIIGAAGSACTSGSLDPSHVLV
                     AMFGAESPRVWETLRFSFGIYNTPAEVDALVAALAKYVPLLKDKTDRGQR"
     aSDomain        complement(15314..16411)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg14_15_Aminotran_5.1"
                     /evalue="2.70E-80"
                     /label="ctg14_15_Aminotran_5.1"
                     /locus_tag="ctg14_15"
                     /protein_end="370"
                     /protein_start="4"
                     /score="261.8"
                     /tool="antismash"
                     /translation="IYIDNAGTTKTAPEVIETMTEALETTWGNASTTNYYGRQAKQMLE
                     DSRHLLARSINAQFDDEIVITSGGTESDNTVVKQVAKARQSEGRHIITTAFEHEAILRP
                     LEDLEQEGFEVTYLPVDERGQISLADLKAALREDTILVTIMTVNNEVGSHLPIHEIGQI
                     VADSNAWFHTDAVQAYGTLPLDVQTDQIDLMSVSGHKLNGPKMVGFLYRRRGIVFPSFV
                     RGGDQELKRRAGTENVPAVVGFARAVELHQEKMAEHRATYVALKHQLVDGLKDAGIDFE
                     VNGSLDEGAAPQVLSLWFKGVPNDALLTNLDLEGIIGAAGSACTSGSLDPSHVLVAMFG
                     AESPRVWETLRFSFGIYNTPAEVDAL"
     CDS             complement(16907..17347)
                     /locus_tag="ctg14_16"
                     /transl_table=11
                     /translation="MFYGMLVPALSAIFIIIVGNKLLAGQVDRGSMAYLLTAPVRRLTV
                     TLTQTLYFIGALVVTFGSMTVTSLLVNHYAEAGFAKKILVELNFGALAIAFAFAGIMFL
                     ASGVFNLSKLSLGTGGVLILAFILLAVIASFVNYGVSGLDDV"
     CDS             17367..17930
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 139.6; E-value: 1.8e-42)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg14_17"
                     /transl_table=11
                     /translation="MALYQGGVDPLIADVMMPTMDGFTMVKEMRAAGFEQPVLMLTAKT
                     TITDKTTGFTSGADDYLTKPVDLAELKLRVAALLRRAKINSARQITIGQTILNEENFTL
                     TINGHSTTLAKKEFLLLFTLLSYPNKIFTQAQLLDQIWGIDSASTEDTVKTHVSKVRKL
                     LKDSNDVKITTIRGLGYKGEICHD"
     CDS             17923..18957
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 190.3; E-value: 1.3e-57)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg14_18"
                     /transl_table=11
                     /translation="MTKNPFTRVLTWLVVLIAFLIVMGTLAFDFALMLTFPHLARNFDP
                     LNPVLALGPTVVILTVVLALTFSWLNKKITYLTKGIDQVAAGNFATHLDEQKGGPLSAS
                     YQNFNQMTDQLAKTATLRNDFINQFSHEFRTPIASIQGFADLMQERELPKKERQAYLAL
                     ISKEAHRLTNLSTNVLTLTTLESQTILNNQTSFDLTEQVRQTVILLWPQLEEHKLNVDL
                     TLAPATAFGNADLLNQVWVNLINNVIKFTPDGGHLTIKIERHDDQIAVSVNNDGPLISP
                     TDQDHLFEKFYQADNRSNVGRLGLGLAIASRIIALHQGRITVVSNPADHTTFTVYLAKG
                     QPSS"
     CDS             19014..19499
                     /locus_tag="ctg14_19"
                     /transl_table=11
                     /translation="MATTLVLYFSASGTTKRMAQTIANLTGADLHEIKAQDPYTQADLD
                     WHDPQSRTSIEQHEHQGHVACVNDFPALDQYDTIIIGHPIWWGIPPRLIANAIDQLPLD
                     GKTLATFATSGGSGYQRSQSYIQRVVDQTHHQVTIIPGTVLSNQRQAKQWLTKANLI"
ORIGIN
        1 gtaatccnga tattcccgaa tgatctaagc gtcttgcgac taatgggagc actactgatt
       61 gaacagaatg aaaaatgggc tgctggtcca cggtacttaa acatgaccgt ttaccacggg
      121 attgaaaaag atgacaattc agaagaagcc ggtatgctta agcttgtgaa atgataaatt
      181 cgcggaattt aatttacacc aacattttgg acttgaccta agtttatcta gcgggatgcc
      241 attaccatat gatatcgaat ccgttatatt gtatacgata caatcttttt caggtctcac
      301 atcattttct tggtattcat cgtcaacatc cagaaagaaa atcttcttgg acgttccgtc
      361 tttaaacgta atggtcacac aagtccgttc atattccctt aggaggtcat atatttcagt
      421 atgtgtgtcg atcaccatct ttattcactc cccagtacta cttaatattc tgtcacagaa
      481 tggttgattt ttaattgcct tccatgcatt cgtattggct gagatagcct gacgcattgc
      541 ctgcatggaa ttagccgcct ggacagtatc aacagtgatc cgggtcgcca tttcgttttg
      601 aactttagct atttttacct cctttctgca taataaaagc cagctattta agctggctcc
      661 gccgttgatt aattaactga aacttgaaag ctgataacct cgcctgtttg acatggttat
      721 cagctttcaa gtttcagtta tacagaataa ggttggtgct ttattaggga tatgtttgag
      781 gagagatcat ttaataccag caagttaggc gtcttgttga gctgcccgtt gttcttctgc
      841 agaaaggcga tccttgatgt atttggcaga ggtagcgagc ttttcttttt cagcagcggt
      901 aaggtccagg tgaagttgtt ccaccacccc gtcacgacca acgactgcgg ggtaggagag
      961 gtacgttccg tattcttcac ggtaatttga aactggcatt tcagtccggg catcacttag
     1021 tagggcattg gtaagccgga ctgcggcagt agcaacaccg tagttggtat acttctttcc
     1081 cttatagacc atgtagcctc cttgccgtgc gcgttcttcc atgtcggtaa ggtcgaggtg
     1141 ccgttcatcc accagatcta gtactcgttt gccgagaacc cggactgttg accaggcagt
     1201 aaattgggag ttaccgtgtt caccaagatt gaagccgacc acggatcgtg agtcaacatg
     1261 gagggcttcc ccaacacatg cgcgcattcg tgcggagtct agcagggtcc ccgtacccat
     1321 cacgtgattc tttggtagcc ccgtgagctt ctgatacatt gaagtgatga cgtcacaggg
     1381 attggtaacg tcgacaagtt tgccatgaaa accgttatca acgagtttct tagcgaccaa
     1441 tggaacctga gtccgggtaa atttaaattc tgcaaagcgg tcgtgatcgg gtgtgtccac
     1501 cagcttagac tttcccagag tagagattac aacgtcacag tcagctaatt gtgaatcatc
     1561 attaacggtt aagtttgtgt ggaacgggag attcgccatg gcgtcacgga ggtcaagcgc
     1621 atcggcacgg acctttgctt cgttagtatc atagagggct aaatcatcag tgaatccacc
     1681 agcaacgaga taatgggcga cagttgcgcc aacgtgcccc attccaacta ctgctacttt
     1741 ccttgtcata ataaaacttc ctttcgatta tcgtattgtt gcctttaatc ttactaatgt
     1801 cagaaatatc actgtctgcc atgatcacca ccacctttaa tatcaaaaca aaaagcgtcc
     1861 tttctagctc ttgataaatc taagaactaa aaaggacgct tgtgcgtggt accacctttc
     1921 tttacgacat aatgtcgcct caaccaaccg ccacaaataa tgtggtatta gccggcacgg
     1981 taatgggtgc taccaatacg ctctactagg gaatccgttc ggcgtacgac tcacgagtga
     2041 ttagtaggtg cggcctctca ctggttcaca ccacccacca gctctcttgc ttcggcctca
     2101 tcgctgtttc tcgctcaacg tctttaactt gtttcaattg attgttaagt actatatcac
     2161 taggcagata gggaagtcaa gataaaaatt aaaaaaagat gagaaaagat gggtgcaaag
     2221 gcagataatt tatagtataa attcgtttga tagcgggcat ttcttgagga aaaattattg
     2281 acacgttagc ttagattgat tatagtttgt tttaaaattt gattagaaaa atgaggaggt
     2341 gagtgcaatg gttggtaata ttaatatttc tacaaataca gccaccctca ccgccaatag
     2401 taatgacgtg atgggcgtga aggattaata aaaaggatgg tggataattg tgtttaaaaa
     2461 agttttagtt gctaaccgtg gtgaaattgc tacacggatt attcgcgcct gtcatgagct
     2521 gggaatcaaa gccgtcgcag tttatgctaa ggaggatgag tatagtgcgc accgctttgc
     2581 tgctgatgag gcgtaccaaa tcggggctgg tgaacatccg cttgatgctt acctggatat
     2641 tgatgaagta attcgggtgg ccaaagaaag cggggcagaa gctgttcacc ctggttatgg
     2701 cttcctggca gaaaacgctg accttgcgca ggcctgtatt gataatggat taaagtttat
     2761 tggacctaag ccggaacacc ttcgtatgtt tggggataag ttggttgcta aacgtgtggc
     2821 cgttgaggca gggctgcaac caattcccgg tttatcgggg gatgttaaaa atgttgacca
     2881 ggtaaaggat tttgctcacc aatatggtta cccgatcatg gttaaggctg ctaatggtgg
     2941 tggcggtcgg gggatgcgga tcatcaatga cgaccagcaa ctcaccgacg agtttgatca
     3001 ggcgaaggat gaggcgctga aggcgtttgg atcggatgag atgtatgtcg aaaaggacgt
     3061 ccaacacccg aagcatattg aagtgcaggt aattgctgat gagcacgggc atgtgatgca
     3121 cctctttgaa cgtgactgct ctgtccagcg ccgccaccag aaggttattg aatttgcact
     3181 tagcgttgtc ttgacccctg agcggcgggt cgaagtttgt ggcctggccg tcaagctgat
     3241 gaagagtgtt cactaccaga atgcggcgac gatcgaattc ttggcgaccc cggatcattt
     3301 ttacttcatt gaggttaatc cccgggtgca ggttgaacac accgttaccg agttgattac
     3361 tgggattgat attgttaaga cccagattcg ggttgcggcc ggtgaagatc ttcatcaaga
     3421 tattggcctt ccccagcaag acgatctcaa gttccacggg gcagccattc agtgccgggt
     3481 cacaacagaa gatcccgaga ataactttat gccagatacg ggacaggtta cgacctatga
     3541 tgcgccaggg ggaaccggtg tccggcttga cgggaacgtc tatcccggct ataaggtcac
     3601 tccttacttt gattccttgc tcgttaagtg ttgtacccgg ggtgaagact tcagtgatgc
     3661 ccggattaag atgctgcggg cgcttgaaga attcaagatt cggggagtca aaactaatat
     3721 tcccttcatg atcaacgtgt taaagcatcc cacgtttatt gccggaaaat gctcgacaac
     3781 gtttatcgac gagaatcccg acctctttag ctttgcgcac cggcccgata cgcctaacca
     3841 gttgctccaa tatattggca atgttaccgt caatggcttt gcaggggtaa ccaagcggac
     3901 caaacttgtt ttgcctgaca tgcaagaacc acaagcaggc caacttacac ctaaccagca
     3961 tacaacaaaa acagcaaagg acatcctgga taaacaggga gccgatgcgg cgatgcagta
     4021 tgttaaggac cagccgaggg tactactgac tgataccaca atgcgtgatg ctcaccaaag
     4081 cctttttgcc actcggatgc ggacgcacga tatgttgccc gcaatgaagg tttacgaccg
     4141 ggcgatgcct aacctctttt ctgttgaaag ctggggcggg gcaacctttg acgtgtgcta
     4201 ccggttcctt ggtgaagacc cgtggacccg attacgatta ttgaagaagt acatgccaca
     4261 tactctccag cagatgttgt tgcgggcgtc gaacgcggtc ggttaccaga attatccgga
     4321 taatgaactg aagcggttca ttgagcacag tgccgcaacc ggggtggatg ttttccggat
     4381 ctttgactcc ctcaactgga ttgaccagat ggaacgtagc attacatatg ttcgggaaac
     4441 cggcaaaatc gccgaaggaa caatgtgctt taccggcgac ttccttagtc ctcacgagca
     4501 caagtacacc ctagattatt acatgaagtt ggcacagtca ttagtcgacg cgggagcgca
     4561 gattattggt attaaggata tggccggcct cttgaaacca aaggccgctt acgaactagt
     4621 cggtagtttg aaggctaagt ttgatgttcc tgttcacctc cacactcatg acacaacggg
     4681 taatggagtt ccaacctacg ttgccgccac aaatgcgggt gttgacgtgg tggacgtggc
     4741 gatgtcttca atggcgggga caaccagtca gcctagttta gccacctttt actacgcgct
     4801 agaaggagat aaacgccaac cggaccttaa tatgcataac gtggcggtct taaaccggta
     4861 ctggtccaat gtccggccgc tttacaacga cttcagcaac ggggtcaacg caccgcaacc
     4921 agacctatac cagacggaaa tgccaggtgg ccagtactcg aacctgaagc aacaggccca
     4981 gtcactagga atcaatgatt ttagcctggt ggaagaaaaa taccgggagg tcaatcagtt
     5041 gctcggtgac atcatcaagg tgacgccaag ctcgaaggtg gttggcgaca tggcaatctt
     5101 catgatccaa aaccaccttg ataaagacaa tatcctgaca aaggggcaac gagtcgactt
     5161 tccagaatca gtggttaact tctttgctgg cgaccttggt caaccatata ggggcttccc
     5221 caaggaccta cagaaggttg tcttgaagga ccatcctgca atcacggttc ggcccgggag
     5281 ccttgctaaa ccggttgatt ttgccgccgt taagcaggaa ctggccgcaa agatcaacca
     5341 ggaaccgagc gaggacgacc tgcagggtta catcatgtat ccgaaagtct ttaccactta
     5401 cttccgcaac catcagcggt acggtgaagt gatggacctt gataccacga cctactatca
     5461 aggtatgcgt cctggtgaaa ttttgcatgt taagtatggt cagggaaaag aaatgattat
     5521 aaaactcgac tttgtttcag caccagatga tgacggtgat cgcttcctct tctttgaact
     5581 ggacgggcgg atccttaaaa taaaagttaa ggacaatagc atgaaggaca aggttgtcag
     5641 tgtttcaaag gctgatcccg ataagagtaa tgagatcggg atgccgttga acgggaacgt
     5701 ggtcaaggtt aacgtagcag aaggtgacca ggtcaaggtt ggtgacgttc tggttgttac
     5761 tgaggcgatg aagatggaat cagcagttaa agcgccattt actggtaagg tgacgaaagt
     5821 atacgctaag gttggcgatg cgttaaagag tcaggacctc ttactaacat tgactgagga
     5881 tgcttgataa ggagagtagc aatgatgtac gaatttccta gactgacagc acatcatatc
     5941 cagacaaccg atcagccagt ggtcacttcg actaacgaaa tggcaaagga acggttaaag
     6001 gtgaaagatc agccctttct catctccgcc cggcagcaaa cggcaggcca cggaaagacc
     6061 agccggaagt tttattcacc cgcgggaagt ggggcctact tcacccttgc cttacccttt
     6121 agctacctgg caaaaagtgc tggtcaggta acggtgactg ccgcggtcgc tgcttatgaa
     6181 gtcctcagca agcaattcac tgttcccatt actattaaat gggtgaacga cctgtactgt
     6241 gagcgaaaga aggtggtggg gattcttgct gaaatggaaa tgaccgcgaa taatcagccg
     6301 cggggaatag tggtcggctg ggggattaac ctggcggcac caactgctcc cttgccgcca
     6361 gcacttcagt tacgtgcggg atggctcggc accacctcaa ttgatgacca tcaacggcta
     6421 caaatcgttg atgcagtcgc tgcgcacttc cttgacctgt tagcaaacgc gtcctggaaa
     6481 cacatcctgc aggtttacca ggctcatcaa taccttatta acaagctgct cctcgttgat
     6541 acaggagcgg aacgtgttag gggatacttt gaccatatta cggatgatgg ctggttatgt
     6601 gtgcagacag ataacgggcc ccgcgcattc atgacgggga cggttcggga actggtttag
     6661 taattaaaaa agcagtcctt cttggacaaa cgcggacgtg ttttgaccgc agttatcctt
     6721 gaaggttcta tgatattcgg taaggataag atgatttctt gtctttaccg ttttttgtta
     6781 cttgctgtac cattgattta aaaataaaaa aagacaactg tcttaagtta tccccataac
     6841 cactcagttg tcttagaaag gatatattcc tcatgactaa tgatatcaat ttttggactg
     6901 gaatcaagga tccttactta aaacctgaca aaccattttt aactgaagat aaagaactaa
     6961 agattatcca tttaattcag tcttatccca tgcactgtcc gctttgcggc cagttgatgc
     7021 gtcgtaatgg cttccgtaag cggcccgtaa cgatcaaaat ccttacaccg gctggaaaac
     7081 cagctgtctt aaaaatcaag aaacaacagt atctctgtcc accatcgccc caatgcccca
     7141 agcgagttac caaggttgcc gagattcaag gagttaattt tgcctgtcga attgcgaatg
     7201 tcgttaaata ccatattgtt caggaactca gtgagagcgt acgtaattaa gtcttgaaca
     7261 tctgtattgt catcctcgga gggcctttga ggcttcttta atcatcaaac gatatcttta
     7321 cataatgtaa atttacagaa gtaagtctaa ttagcgccgt tagagtaatt acctgaaaag
     7381 agcggcgatg caaaagacga ccagtttcaa ttccacccac catttcctca tatctggtcc
     7441 tcccctcgat aaattatgtg tgcttttgcg tactggttgc aacactaata caaaatcggg
     7501 gccaacttaa atcgactgcg tagtggcgcc cctttcataa cagttagccg acgacttctc
     7561 gattgattta cataatataa aattaaaaaa tgtgatttag gtaatccccc aatggtcacc
     7621 cggcaacttt ctaagcataa tagtagccaa tttgtgaatt aatgtttatg attgttggtt
     7681 ggtgctggga cgttcatcag ggtgatggtt gcggtagccg ttaatcggtc gttaaccagt
     7741 agccgggctt gccaggtctg aagtgtgcga ccaacgtgat caggggttgc aaccacaaaa
     7801 atctcccctt cccgtatcgc acggatatgt tgtgtggtaa cattgacccc gaccgcgatt
     7861 cgccccggcg ctacgttggc gttagcccct agggaggccg cggtttccgc cagcacggtg
     7921 ttaattccgc cgtgaacgat cccgtacggt tgcaagtgct ttgcttggac cggcatggag
     7981 agttcaacgc ggtctttggt caccaagtcc tggtgaatgc ctaagttttc aagtaaattc
     8041 atttttgtac ctctggattt tgtaaaggag tttgttatga cgagtgctaa ctggaccccc
     8101 gttaaggagt attccgaaat tatttttgaa cgcgacgata agattgccaa gattacaatg
     8161 aaccggccgg aaaagcacaa tgccttcacc ccggtaacgg tcgccgaaat gatcaacgcg
     8221 tttaacatct gtcgtgatga tagcacaatt ggcgtgatta ttcttaccgg agccggcgat
     8281 aaggcctttt cttccggtgg tgaccaatcc gtgcggggta acgggggtta cgtgggcccc
     8341 gaccacatcg cccggctcaa cgttttggac ctccaacact tgattcggat catccccaag
     8401 ccggtgattg ccatggtcaa gggctggtca gtcgggggcg ggaacgtctt acaactggtt
     8461 tgtgacctga cgatcgccgc cgataacgcc atgtttgggc aaacggggcc gaaggtgggt
     8521 tcctttgacg ccggttatgg ctcgggttac ctagcccggg tgatcggcca caagcgggcc
     8581 aaggaagttt ggttcttaaa ccacttctac acggctgacg aagcttacca aatgaactgg
     8641 attaacaagg tggcgcccct agctgaggtc gaatcagtta ctttagactg gtgtcatgaa
     8701 atcttaaaga agtcaccgac cgcccttcgc ttcattaagg cggccatgaa cgccgataca
     8761 gatggtttag cggggcttca acaatttgcc ggtgacgcca cgatgcttta ctacacgact
     8821 gacgaaggaa aggaagggcg cgacgccttt aaccaaaagc gcgaccccga cttcgataag
     8881 ttcccgaagt tcccgtagga ggccgtcatg gagattccaa attggctcct caaacaggct
     8941 tcgctaaacc ctaaccgggt ggcggttaac gacggtacca ccgcctacac ctttgcccag
     9001 ctggttcccc tggtcgccca ccgtgctggc cagattcaag cgcagacgga ccagccccgg
     9061 gttggggtga tgacccacaa taacctggct ggttacttag ccgccctggg ggtcttagcc
     9121 gccgacaaga ccatcgtttg gctaaattgg cgccttgccc ctgaagaact gagccgccaa
     9181 atcggcgacg cggggctcga cctagtctta gtcgatgacc aactagccga ccgctattac
     9241 ggtgggcacc gggtcctctg ttcggaattg acagccggca ctgccccggc ggcagtgttg
     9301 acgccgacgg ttgacctaga cgccgtggcc tcgatcatgt acacctcggg aaccaccggt
     9361 cagccaaagg gcgtcttgca aacctacggc aaccacttgg cctccgccat ttcgtcatct
     9421 ttgaacctcg gggtgttgcc aaacgacctc tggttgtgcg tcgcccccat cttccacatt
     9481 tcgggctttt caattctaat gcggggcctg atttacggga tgggcgttcg cctagtcaac
     9541 catttcgatg cgcaagtggt caaccaaatc ctggaggacg aaccggttac gatcatttcg
     9601 gccgttccct acatgctaaa gaagatgctc gaagacgtcc aagcaaatga ccactgttac
     9661 tcatcggcct ttcgcctggt gctactcggc ggtgggacga ttgaccgggc gacccttaac
     9721 gcctgcgaag aaagtgggct gccgattgtc cagtgttacg ggatgaccga aacttgctcg
     9781 cagttcgttg ccctctcggc tgaagaggcg ccttaccacc ttggttcggt cggtaagccc
     9841 ctgtttacca cccagctgcg tttggtgggt gagcatcacg aaatcgagat ccagaccccg
     9901 gccttaaccc cgggttactt aaaccaaccg gccaagtttg cggctaagca cgatggcgac
     9961 tggtaccgaa ccggcgacgt cggccacttt gatgaagacg gtttcttgta cgtcgacgga
    10021 cggttagatg aaatgatcat ctccgggggc gaaaacattt tccccgccga ggtggaaaac
    10081 gtcttgcgcc agtacccagg catccaagaa attgccgtgg tcggccgtaa tgatcaacag
    10141 tggggcgccg ttcccgtggc cgtggtcgtc agcaaacaac ccgtcgactt tcagcagttg
    10201 gaggccttcg ggcgtgaaca cctggcccac tataaggtac ccaaggtcta cttgcaaaca
    10261 gacgccctac cgaaaaacgc cagcggcaag gtccaaaagt ttcgcttaca agacctggtc
    10321 gctaacgctt agtcatgcca caacagaata atcaattgag aaaagaaaga tacaaataaa
    10381 tgatggatgc aaaacccaac cgccgggcgc tgtcgctcgg ttcctttgtg attttatacc
    10441 ttggttacat gctcttattc gccgaccgga ccgtgcttaa cttatcgttg gccgcgatcg
    10501 gcaaggattt ctccgttagc ccggccgcac tgggggcgac tagttccgtc ttcttcttgg
    10561 gctacacgat catgcaaatc ccggggggct ggctgaccga ccgcttctct tcccgtaagg
    10621 tgatcatcgc caccctcgcc ttttggtcgg tgatgacgat ctttaccggg ctggcctggt
    10681 ccttagccgc cctcttggta attcggttcc tgtttgggat cgccgagggc ccttacccac
    10741 cggccgccat gaagcaagtc gcccaggact tcccggtcaa caagcgtgcc caactgaccg
    10801 ccgccttaat ttcctctaac tacgccggcg cggccctggc ccctttcatc atcgtgccaa
    10861 tcatcgccgc taccggttgg cgctcggcct tcttctggtt ggggggcttt ggcctactct
    10921 tgatggtcag ctacctcttc ttccgcggtc acggcggtgg acaaacggta acgaaacaag
    10981 aacggcaaaa gataaactgg aaggaaatcg acccgcgggt ctgggccttc gtggtgatcg
    11041 ggctggcctt aaacattatc accaagggga tggaaacctg gatgccggtt tacttcttaa
    11101 acgcccgcca catcaactta gccaacttgg cttggttagt tcccctaccg acgattgccg
    11161 gggggattgc ggccttgatt tccggttacg taatggtgca catctttaaa aatcaagaac
    11221 gcctgatgat tatcctggcc tcctttttaa cggtcctgac catgtttgga ctctacaagt
    11281 ccaccagcct ggtttggtta gtgatcttcc aaatggccac ctacttcgtc aagtcgctag
    11341 ccttcaccgg gatcttctcc tacgcggccc aactcttccc gcaaaagact tatggctccc
    11401 agatcgggac gattaacttt ggtggccaac tcgggggctt cttcggtccc ctcttaatcg
    11461 gctggatcgt tcagttgagc ggttcatacg acacggcctt cttcggcctg gtcatctccg
    11521 ccttggtggc cggggtggcg tccctcttca ttgggaattt aaaagctaaa taatccgcta
    11581 attatagaat gattaatgac tgtggtgacc tcgtacggga ttatcacagt cattttattt
    11641 atttcaaatc aatttcttaa ctatcataat ccctgttatt ttaacccttt cagagaatgt
    11701 ggacgctttc tttaaaatta attaaactca catatgaaga cttggttata acatgattta
    11761 tgttagaatg acggcaacta atcaagaaag gtggtagtta tgaatgaaag gttttgcaat
    11821 gctgggcccc aacaagacgg gctttattga aaaagaagat cccaaggtgg gcagccgtga
    11881 cgccctggta cgtcccctag ccgttgcccc gtgtacttct gacatccaca ccgtgtttga
    11941 agatgcctag ggccacggga gaatatgatt ctcggccacg aagcctgcgg ggtggttgtg
    12001 gaagtcggtg aagacgtcaa ggactttaaa ccgggtgacc gggtactcgt tccggcgatc
    12061 acgccaaact ggtctgacgt ttactcccaa gctggctacg ccactgattc cgacgggatg
    12121 ctgggcggct ggaagttctc taatatcaag gacggggtct tcgccactcg tttccacgtt
    12181 aacgacgccg acgggaacct ggctcaccta ccggatgaaa ttgacccggc cgaggcctgc
    12241 atgctttccg acatgatccc aactggcctc cacgcttccg aaatggcggg cgtgaccttt
    12301 ggggatgacg tcgccgtgat tgggatcggc ccggttggct tgatggccct gcgcggggcg
    12361 gtgctccacg gggctggccg cgtctttgcg gttggttcac gggaaaagac ggtcgaagtg
    12421 gctaaaaagt acggcgcaac cgacatcatt gactaccaca acggccggat ttccgaccaa
    12481 atcctggaag ccactggtgg ccaaggggtc gacaaggtcc tgatcgccgg tgggaacgcc
    12541 aaggacacct ttgaagaagc cgtccggatg ctcaagccgg gtggctcaat cgggaacgtt
    12601 aactacttaa acggtcacga cgacgtggtc ttcaacgccg gtgactgggg tgttgggatg
    12661 ggtcacaaga ccatccacgg tggcctgatg cctggtggcc gcctgcggat ggaaaagctg
    12721 gccgtcctcg tggtgaacgg ccggatcgat ccatcactaa tgatcaccca tcgcttcgaa
    12781 ggcttcgaga agattccgga cgccatcgaa ctgatgcacc acaagtcggc ggacttaatc
    12841 aagccggtcg taatttgcaa cgatatcgac taattaaaag ggagtggcaa ataacttgct
    12901 tggcaggtcg tatgactaag ctaggggcgg aacgcatcgt tcttcggccg gcttagacac
    12961 taggcctgtg gttattgacc acgttttcta tctaacatac gcaaagtcaa ccaccactga
    13021 ctaaagtcag tggcttgtga gcaagcaccc ttctgatgag tgtttgaatc acaatttgca
    13081 tagatacacc actgcgaaca gttctacgaa ccgtttcgtc ttacacggca attaccaatg
    13141 cctttagcgt ccccaggttg ccatagggac gagccaaatt aggctaattt aataattcct
    13201 ttagttagaa tattctgcgc agcgttatgg tcacgaacgt ggtgagcatg gcactttggg
    13261 catgtccatt ctcggtctgc aagtgtgagt ttttcggtcc ctgctgtgcc catcacaaaa
    13321 ccacattcat ggcaagcctg cgtagtgttc ttaggatcca ccgtaaggaa ttggcgatgg
    13381 tagagttctg ctttataagc caacattcct aagaaagtcc gccaacctac gtccgcaata
    13441 ctcatcgcta aagcatgatt cttcagcata tttttactcc gcaattcctc tgcggctacg
    13501 aaatcgtggt tcttgattag tgtagtcgag acattgtgga gaaagtcacg tcgacgttca
    13561 aagacttggg cgtgtaattt agccaccaac aagcgttgct tttggtagtt cttactagtc
    13621 cgtaatggcc gatgttcttg tttggcccga cgagcccgtc gcgataagat gcgctgtgct
    13681 ttggctaagc gacccttaat tatgcggtaa tagcgtggat tagccacagt atcgccatta
    13741 ctagtagtta agaagttttc agtattaaga tcaatcccaa tctgcttgcc tgtattttgc
    13801 ggccaattga caaagggagt atccgacgct aactgcattg agagaaagaa acgaccgcta
    13861 gcgtccttta cgatggttac cgttccaata cgggtttcag cactgcgagc taagactcgt
    13921 tgatgggaac ctttaacacg gagccgacct aatttaggca ctataacatg cttactatct
    13981 tcaaaatgta cagttccgtt agttaagtat gctgccttct gtttcaaata ctggcagtta
    14041 gtttgataac gccagacgta acttttccgg tgaaacttag gcacacctgc agtatgaact
    14101 ttgcgaaaag cattccaagc tttatggtag ttttgaatgg cattggcttt agtcaagcta
    14161 tcgatccttt tatcttctaa gaactggaaa tgattagaca tttgtttagc gctttggcga
    14221 agctccagtt gctcaatccg gttctgaatg gtatcaatcg ggagtttaac ctgttttagc
    14281 cgccaaagtt ccttgttaat agcgaccatt tcgttataga tgaatcgact agcatcacta
    14341 ttgatcttga taattttctt ttgcctgtcg cttggataaa tccgcacctt gagtccgtaa
    14401 tgatatttca tctgcgccat tgacttcatt tattttcacc tccttcactg atatagtgtt
    14461 attataccac atgtcaatga caataataat taaggagcgt ggcaatcatg tcgaaggaca
    14521 aaatcgaaga tgccatttat acacggcgtt atatttataa ctttcactac catttgattt
    14581 gggtaaccaa gtatcgtaat ccaactttta ctagtgaagc gttagtgaat gaaatgaaag
    14641 aaatncttac aacggttgcg gcagataacg aaatcgtgat tgagcacatg gaagtaatgc
    14701 ctgaccacgt ccatgtgttg attagttttc cacctagtaa agcaccaact agcgctatca
    14761 aagccctcaa aggacgcagt gccttcattt tcctcaagcg acacccggaa atccgccagt
    14821 cgcagtattg gggtggccac ctctggtccc ctagctatta catgagtact ttagggaata
    14881 tgagcaagga ggtcgttgag caatatatca ataatcaaaa gtacaatgaa ataaaaaaac
    14941 gccctaaagg acgtaagtag aagcctatcc atcccatgac taaagtcacg ggattccggc
    15001 caatatttat taaaacagtg gccagtaatt cggcgacggc caattcgttg ccgtcgtccg
    15061 aatcaatccg gatcagactt tttagtagtt caatcttttc ttgtcgttgc atggcgcatc
    15121 cccccatcat aaaaccccgg tgccagaacg aatctgccca ccggggtgaa agcttgcgtc
    15181 ctcatctcgt aaacctaggt tagcaaaccc aaatgagaaa aaacaagcgc gtctttaatt
    15241 tatttttaat ttaacgttga ccgcgatcgg tcttgtcctt taataggggg acatacttgg
    15301 ccaaggcggc caccaaggcg tcgacttctg ccggcgtgtt gtaaatgcca aaggagaagc
    15361 ggagggtttc ccaaacccgc ggactctcgg cgccaaacat cgccactaac acgtgggaag
    15421 gatccaggga cccggacgtg caagccgacc cggcggcccc gatgatccct tccaagtcga
    15481 ggttggttaa gagggcgtcg ttaggcaccc ccttaaacca cagcgataaa acttggggcg
    15541 ctgcgccttc atccaaactc ccgttgactt caaagtcgat cccagcgtct tttaacccat
    15601 ccaccagctg gtgctttagg gccacgtagg ttgcgcggtg ctcggccatc ttctcttggt
    15661 gcagttcgac agcccgggca aagccgacca ccgctggtac gttttcggtc ccggcccggc
    15721 gctttaactc ctggtcgccg ccgcgcacaa aggacgggaa gacgatcccg cggcgccggt
    15781 acaagaaacc aaccatcttt gggccgttga gcttgtggcc ggataccgac atcaagtcga
    15841 tctggtccgt ttggacgtcc aacggcaagg tcccgtatgc ttgaacggcg tcggtgtgga
    15901 accaggcgtt ggaatcggcg acaatttggc caatttcgtg gattggcaag tggctgccga
    15961 cctcattgtt gacggtcatg atcgtgacta gaatcgtgtc ctcgcgcaag gcggccttca
    16021 agtcggctaa gctaatctgg ccccgctcgt cgacgggcag gtaggtcacc tcaaagccct
    16081 cttgttccaa gtcttctagg ggccgcaaga tcgcctcgtg ttcaaaggcg gtcgtaataa
    16141 tgtggcgccc ctcactttga cgggccttgg ccacctgctt gacgaccgtg ttatcacttt
    16201 cggtgccgcc actggtgatc acaatttcat cgtcgaactg ggcgttaatc gaccgggcca
    16261 ggaggtggcg tgaatcttcc agcatctgtt tagcctgacg cccgtagtag ttggtcgtcg
    16321 aggcgttccc ccaagtcgtc tccagcgctt cggtcatcgt ttcaatgacc tccggggccg
    16381 tcttggtggt gccggcgtta tcaatgtaaa tccgcttatc caaaaaaatc gctcctcatt
    16441 ttaaatattg ctggccgaat tctcaaccgt tctagtatac tacttatttt tagatagaga
    16501 aggggaaagc ctttataaag cggtacaata cgaggacagt acaaacacac cgtgtgcagt
    16561 tggtgctttt ctagccaacg aaccggttcg ggtgccttta aggtaccctt tttttgtacc
    16621 cacaaagcta aaaatcctgt caataaatta ccatcatggt agcccatcaa caggatttag
    16681 tgtagagcca gttttttgga atttcctgat cacaaaacgg ccgccggacc aacagtccag
    16741 cagccgttct taatctttat aacggtaaat cctttttgtt aaaggcgagg ttgccccccg
    16801 caaagcaaac ggcgcctagc ccgcctaaaa tcgccagttt tccttgccaa gcatctcctt
    16861 gggccataac gtctttgtaa tcaaacagcg atacaatcgt caggtgttaa acgtcatcca
    16921 acccactgac cccgtagttg acaaaagaag caatcacggc taacaagatg aaagctaaaa
    16981 ttaagacccc cccggtcccc agggatagct tagagaggtt aaacaccccc gaggctaaaa
    17041 acatgattcc cgcaaaggca aaggcaattg ccagggcgcc gaagtttaat tcaaccaaaa
    17101 ttttctttgc aaaccccgct tctgcgtaat ggttgaccaa caaactggtc accgtcatcg
    17161 agccaaaggt caccaccaac gcgccaataa agtacagcgt ttgggtcagc gtgaccgtta
    17221 gccggcgaac cggcgccgtc aacaggtagg ccatcgagcc ccggtcaacc tggccggcca
    17281 gcagcttgtt gccgacaatg ataatgaaaa tggcgctcaa ggctggtacc agcatcccgt
    17341 aaaacatcgg tcctagcagg gccctagtgg cgctttacca agggggtgtc gaccccttaa
    17401 ttgccgacgt gatgatgccc accatggacg gcttcacaat ggttaaggaa atgcgggccg
    17461 ccgggtttga acaacccgtt ttgatgctga cggccaaaac cacaatcacc gataaaacca
    17521 ccggcttcac tagtggggcc gacgattacc tcaccaaacc cgttgaccta gccgaactca
    17581 agctccgggt ggccgccctt ttgcgccggg ctaagattaa cagtgcccgc cagattacaa
    17641 tcggtcagac cattcttaac gaagagaatt ttactttgac catcaatggc cactccacca
    17701 ccctagccaa aaaggagttt ttgcttctct tcaccttgct ttcctacccc aataaaattt
    17761 tcacccaggc ccagttactc gaccagatct ggggaattga ttcggcctca acggaagaca
    17821 ccgtcaaaac ccacgtctca aaggttcgca agttacttaa ggatagtaac gacgtgaaaa
    17881 tcaccaccat ccgtggcctc ggctacaagg gagaaatttg tcatgactaa aaatcccttt
    17941 acccgggtcc tcacctggct agttgttttg atcgcttttt tgatcgtgat gggaaccctg
    18001 gcctttgact ttgctttaat gctgaccttt ccccacctgg cccgcaattt cgacccgctt
    18061 aacccagtgc tggccctggg ccccaccgtg gttatcttaa cggtggtctt agccctaacc
    18121 ttttcttggc tcaacaaaaa aatcacctac ttaacaaagg gtattgacca agtggccgcc
    18181 ggaaattttg ctacccacct cgatgagcaa aagggtggtc ccctatcagc cagctaccag
    18241 aacttcaacc aaatgactga ccaactcgct aaaaccgcta ctttgcgcaa cgactttatc
    18301 aaccagttct cccacgaatt tcgcaccccg atcgcctcaa tccaggggtt tgccgaccta
    18361 atgcaagaac gggagctacc aaaaaaagag cggcaagcct acctggcttt gattagtaag
    18421 gaggcccatc gtttaacgaa cctgtctacc aacgtactga ccctaaccac gttagagagt
    18481 caaaccattt taaacaacca gacttcgttt gacctaactg agcaagttcg tcagactgtc
    18541 atcctcctgt ggccccaatt agaagaacac aagcttaacg ttgacctaac gcttgctccg
    18601 gcaaccgcat ttgggaacgc tgacctgttg aaccaggtct gggtcaacct aatcaataat
    18661 gtcatcaaat tcacaccaga cggggggcac ctaacgatta aaatcgagcg ccacgacgat
    18721 cagatagccg tgtccgttaa caacgacggt cccctgatct cacccactga ccaggaccat
    18781 ctgtttgaaa aattttacca agccgataat cgttccaacg tcggcaggct tgggcttggc
    18841 ctcgccattg ccagccgaat tattgctctc catcagggac gcatcaccgt ggtttcgaat
    18901 cctgctgacc ataccacctt caccgtctac ctagcaaagg gtcagccaag tagttagaag
    18961 aaccttttta attgtaatat aattaaaata gttaaatatt atgagggatt ttaatggcaa
    19021 ctacgctcgt cttgtacttt tcagcatccg gcaccaccaa acggatggcc caaacgattg
    19081 ccaacttaac cggggccgac cttcacgaaa tcaaggccca agacccatac acccaagcgg
    19141 acctggactg gcatgaccct cagtcacgga cctcaattga gcaacacgaa caccaggggc
    19201 acgtcgcctg cgtcaacgac tttccggccc ttgatcaata cgacacgatc atcatcggcc
    19261 acccaatttg gtggggaatt ccgccccgtt tgattgctaa cgccattgac caacttcctt
    19321 tagatggcaa aacgctggcc acctttgcca cctcgggggg ctccggttat cagcgcagtc
    19381 aaagctatat ccaacgcgtc gttgatcaaa cccaccacca ggtgacgatc atccccggca
    19441 ctgtgttgag caaccagcgc caggcgaagc agtggctgac caaggcgaac ttaatttagt
    19501 tggtagccgg agcggttatt tctaagggcg ccgctcattt tcagaaaagc ccttaccaaa
    19561 aaatccttta caagtgatcc gtttcccagc ataatgtagt caattaaata aataatttct
    19621 tcggggcagg gtgaaaatcc cgaccgacgg tgacaagcaa tgcttgaagt ccgtgacccg
    19681 caaatttgcg gctgaaccag tgcgattctg gtaccgacag tgaaagtctg gatgggagaa
    19741 gaaaaggcag ggggaagtcc cctgccacct ttttgaacac gctttcaacc aggggtcccg
    19801 gaatttttcc ggggcccctt ttaaatttcc cggggaaatg ggaatggcaa cctcctcggc
    19861 gggccgagga ggttggttcc cactcaccta tgaaaggaag tcattacctt gagttcagac
    19921 gaacagttca tgcaactggc gctcgctgaa gcggccaagg gcgggagcgc cacctggaag
    19981 aacccccagg tcggcgccgt gatagtcaaa gacggccagc tgctggcgac gggctaccac
    20041 caccagtatg gtcaggccca cgccgagcgc gacgccatca gtaagctttc taacgaacag
    20101 ctggccgggg ccacgattta cgtcaccctg gagccctgct ttcactacgg caagcagcct
    20161 ccgtgtagcc agttgttaat tgacagccac tttgcccggg tggtcgtcgc cacgattgac
    20221 ccccaccaag tcgttggtgg caagggaatc gcccagctaa aggcggccgg aattgatgtg
    20281 gaggtcgggc tcttaaagga ccaagccgag gccctcaacc gccactactt ct
//
